imipramine and quinacrine

imipramine has been researched along with quinacrine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199010 (38.46)18.7374
1990's2 (7.69)18.2507
2000's8 (30.77)29.6817
2010's6 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Chiang, GH; Unger, SH1
Pajeva, I; Wiese, M1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Elshorst, B; Fiebig, K; Griesinger, C; Grimme, S; Jacobs, DM; Vogtherr, M; Zahn, R1
Dollinger, S; Gmeiner, P; Klingenstein, R; Korth, C; Löber, S1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Drenckhahn, D; Lüllmann-Rauch, R1
Benveniste, J; Cazenave, JP; Mustard, JF1
Da Prada, M; Picotti, GB; Pletscher, A1
Greengard, P; Quinn, GP; Reid, MB1
Hadwiger, LA1
Szustkiewicz, C; Van Dyke, K1
Grudev, FI1
Andersson, A; Olsson, S; Tjälve, H1
Harty, DW; Thakur, A; Webb, BC; Willcox, MD1
Arnone, MR; Snyder, RD1
Ai Tran, HN; Chanana, M; Krol, S; Legname, G; Mandal, S; Moda, F; Morbin, M; Sousa, F; Tagliavini, F; Vimercati, C1

Other Studies

26 other study(ies) available for imipramine and quinacrine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship

1981
Molecular modeling of phenothiazines and related drugs as multidrug resistance modifiers: a comparative molecular field analysis study.
    Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11

    Topics: Antineoplastic Agents; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Conformation; Phenothiazines; Thioxanthenes; Tumor Cells, Cultured

1998
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Antimalarial drug quinacrine binds to C-terminal helix of cellular prion protein.
    Journal of medicinal chemistry, 2003, Aug-14, Volume: 46, Issue:17

    Topics: Antimalarials; Binding Sites; Chloroquine; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Peptide Fragments; Phenothiazines; Prions; Protein Structure, Secondary; Quinacrine; Recombinant Proteins; Structure-Activity Relationship

2003
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
A chimeric ligand approach leading to potent antiprion active acridine derivatives: design, synthesis, and biological investigations.
    Journal of medicinal chemistry, 2006, Nov-02, Volume: 49, Issue:22

    Topics: Acridines; Animals; Blotting, Western; Cell Line, Tumor; Densitometry; Drug Design; Imipramine; Indicators and Reagents; Ligands; Mice; Prions; PrPSc Proteins; Quinacrine; Structure-Activity Relationship

2006
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics

2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Experimental myopathy induced by amphiphilic cationic compounds including several psychotropic drugs.
    Neuroscience, 1979, Volume: 4, Issue:4

    Topics: Amitriptyline; Animals; Chloroquine; Chlorphentermine; Chlorpromazine; Female; Imipramine; Iprindole; Male; Microscopy, Electron; Muscles; Muscular Diseases; Phentermine; Piperazines; Psychotropic Drugs; Quinacrine; Rats; Triparanol

1979
Aggregation of rabbit platelets by platelet-activating factor is independent of the release reaction and the arachidonate pathway and inhibited by membrane-active drugs.
    Laboratory investigation; a journal of technical methods and pathology, 1979, Volume: 41, Issue:3

    Topics: Animals; Arachidonic Acids; Blood Platelets; Cell Membrane; Chlorpromazine; Edetic Acid; Egtazic Acid; Fibrinogen; Humans; Imipramine; Lidocaine; Methylprednisolone; Platelet Aggregation; Prostaglandins; Quinacrine; Rabbits; Reserpine; Serotonin

1979
Uptake and liberation of mepacrine in blood platelets.
    Naunyn-Schmiedeberg's archives of pharmacology, 1976, Volume: 292, Issue:2

    Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Animals; Blood Platelets; Cell Membrane; Chlorpromazine; Cocaine; Cyanides; Female; Fluorides; Guinea Pigs; Imipramine; In Vitro Techniques; Male; Ouabain; Quinacrine; Reserpine; Serotonin; Temperature; Thrombin

1976
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
    Molecular pharmacology, 1966, Volume: 2, Issue:4

    Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine

1966
Increased levels of pisatin and phenylalanine ammonia lyase activity in Pisum sativum treated with antihistaminic, antiviral, antimalarial, tranquilizing, or other drugs.
    Biochemical and biophysical research communications, 1972, Jan-14, Volume: 46, Issue:1

    Topics: Antidepressive Agents; Antitussive Agents; Antiviral Agents; Chloroquine; Deamination; Ethylamines; Fluorenes; Histamine H1 Antagonists; Imipramine; Ketones; Lectins; Leucine; Lyases; Parasympatholytics; Phenothiazines; Phenylalanine; Piperidines; Plant Lectins; Plant Proteins; Plants, Edible; Propantheline; Quinacrine; Stimulation, Chemical; Tranquilizing Agents; Trimeprazine

1972
Apparent new modes of antimalarial action detected by inhibited incorporation of adenosine-8-3H into nucleic acids of Plasmodium berghei.
    Military medicine, 1969, Volume: 134, Issue:10

    Topics: Antimalarials; Culture Techniques; Imipramine; Malaria; Microbial Sensitivity Tests; Nucleic Acids; Nucleosides; Plasmodium; Quinacrine; Radioisotopes

1969
[Experience with the use of acrichine in patients in depressive states and catatonis(preliminary report)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1966, Volume: 66, Issue:10

    Topics: Adjustment Disorders; Adolescent; Adult; Antidepressive Agents; Bipolar Disorder; Catatonia; Chlorpromazine; Depression; Female; Hallucinations; Humans; Imipramine; Male; Middle Aged; Quinacrine

1966
The uptake of 14C-chloroquine by mouse pancreatic islets in vitro.
    Acta pharmacologica et toxicologica, 1980, Volume: 47, Issue:1

    Topics: Absorption; Animals; Chloroquine; Chlorpromazine; Desipramine; Glucose; Hydrogen-Ion Concentration; Imipramine; Islets of Langerhans; Lidocaine; Mice; Nicotine; Nitrogen; Ouabain; Quinacrine; Temperature

1980
Interactions between Candida species and platelets.
    Journal of medical microbiology, 1998, Volume: 47, Issue:2

    Topics: Anticoagulants; Apyrase; Blood Platelets; Candida; Cells, Cultured; Complement Activation; Complement System Proteins; Edetic Acid; Humans; Imipramine; Interleukin-1; Interleukin-8; Neutrophils; Platelet Aggregation; Platelet Aggregation Inhibitors; Quinacrine

1998
Putative identification of functional interactions between DNA intercalating agents and topoisomerase II using the V79 in vitro micronucleus assay.
    Mutation research, 2002, Jun-19, Volume: 503, Issue:1-2

    Topics: Animals; Anthracenes; Catalysis; Cell Line; Cricetinae; Cricetulus; Imipramine; Intercalating Agents; Micronucleus Tests; Mutagens; Quinacrine; Topoisomerase II Inhibitors

2002
A novel class of potential prion drugs: preliminary in vitro and in vivo data for multilayer coated gold nanoparticles.
    Nanoscale, 2010, Volume: 2, Issue:12

    Topics: Animals; Brain; Cell Line; Gold; Imipramine; Metal Nanoparticles; Mice; Polyamines; Polystyrenes; PrPSc Proteins; Quinacrine; Survival Analysis

2010