imipramine has been researched along with protriptyline in 47 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 29 (61.70) | 18.7374 |
1990's | 2 (4.26) | 18.2507 |
2000's | 7 (14.89) | 29.6817 |
2010's | 8 (17.02) | 24.3611 |
2020's | 1 (2.13) | 2.80 |
Authors | Studies |
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Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
Dudley, MW; Kane, JM; Miller, FP; Sorensen, SM | 1 |
Topliss, JG; Yoshida, F | 1 |
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
Bartoccini, F; Carminati, P; Castorina, M; Di Cesare, MA; Di Serio, S; Gallo, G; Ghirardi, O; Giorgi, F; Giorgi, L; Minetti, P; Piersanti, G; Tarzia, G; Tinti, MO | 1 |
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K | 1 |
Colau, D; Dolusić, E; Frédérick, R; Larrieu, P; Masereel, B; Moineaux, L; Pilotte, L; Pochet, L; Stroobant, V; Van den Eynde, B; Wouters, J | 1 |
Anzini, M; Brogi, S; Butini, S; Campiani, G; Cappelli, A; Caselli, G; Castriconi, F; Gemma, S; Giordani, A; Giorgi, G; Giuliani, G; Lanza, M; Letari, O; Makovec, F; Manini, M; Mennuni, L; Valenti, S | 1 |
Belyakov, S; Dambrova, M; Kazoka, H; Kuznecovs, J; Lebedev, A; Liepinsh, E; Mishnev, A; Orlova, N; Ponomaryov, Y; Vavers, E; Veinberg, G; Vikainis, S; Vilskersts, R; Vorona, M; Zvejniece, L | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E | 1 |
Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E | 1 |
Cardoso, FC; Duggan, PJ; Kuiper, MJ; Lewis, RJ; Schmit, M; Tuck, KL | 1 |
Hollister, LE | 1 |
Richelson, E | 1 |
Levine, RM; Maickel, RP; Spaulding, JH; Zabik, JE | 1 |
Hollander, CS; Tai, HH | 1 |
Roth, JA | 1 |
Hullin, RP | 1 |
Korf, J; Meisch, JJ; van Wijk, M | 1 |
Binks, SM; Greenwood, DT; Murchie, JK | 1 |
Huey, LY; Janowsky, DS; Risch, SC | 1 |
Stewart, MJ; Watson, ID | 1 |
Detaevernier, MR; Dryon, L; Massart, DL | 1 |
Tyber, MA | 1 |
Schildkraut, JJ | 1 |
Lagerström, PO; Theodorsen, A | 1 |
Graf, U; van Schaik, N | 1 |
Cunha, UV | 1 |
Alroy, GG; Lavie, P; Peled, R; Rubin, AH | 1 |
Audus, KL; Gordon, MA | 1 |
Beierle, FA; Hubbard, RW | 1 |
Harrison-Read, PE; Steinberg, H | 1 |
Amsterdam, J; Brunswick, D; Mendels, J | 1 |
Forker, AD; Marshall, JB | 1 |
Lyskowksi, J; Nasrallah, HA; Schroeder, D | 1 |
Friedel, RO | 1 |
Bannister, SJ; Dolan, JW; Snyder, LR; van der Wal, S | 1 |
Evans, DL; Golden, RN | 1 |
Robins, E; Welner, A; Welner, Z | 1 |
Creasey, DE; Mirin, SM; Schatzberg, AF | 1 |
Hanson, WL; Kinnamon, KE; Poon, BT; Waits, VB | 1 |
Azar, N; Korobkova, EA; Ng, W; Nizamova, M; Venkatratnam, A; Williams, AK | 1 |
5 review(s) available for imipramine and protriptyline
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Tricyclic antidepressants (first of two parts).
Topics: Aged; Amines; Amitriptyline; Antidepressive Agents, Tricyclic; Chemical Phenomena; Chemistry; Child; Depression; Desipramine; Doxepin; Humans; Imipramine; Kinetics; Neurotransmitter Agents; Nortriptyline; Protriptyline | 1978 |
Blood levels of tricyclic antidepressant drugs: assay procedures, reproducibility and relationship to therapeutic outcome and side effects.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Interactions; Female; Humans; Imipramine; Kinetics; Nortriptyline; Protein Binding; Protriptyline | 1977 |
The clinical application of tricyclic antidepressant pharmacokinetics and plasma levels.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Desipramine; Doxepin; Heart; Humans; Imipramine; Nortriptyline; Protriptyline | 1980 |
Cardiovascular effects of tricyclic antidepressant drugs: therapeutic usage, overdose, and management of complications.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovascular System; Child; Depression; Desipramine; Doxepin; Electrocardiography; Hemodynamics; Humans; Hypotension; Imipramine; Kinetics; Middle Aged; Myocardium; Norepinephrine; Parasympatholytics; Protriptyline | 1982 |
2 trial(s) available for imipramine and protriptyline
Article | Year |
---|---|
Blood levels of tricyclic antidepressant drugs: assay procedures, reproducibility and relationship to therapeutic outcome and side effects.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Interactions; Female; Humans; Imipramine; Kinetics; Nortriptyline; Protein Binding; Protriptyline | 1977 |
Effect of tricyclic antidepressants on individual symptoms.
Topics: Affective Disorders, Psychotic; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Humans; Imipramine; Protriptyline; Psychotropic Drugs; Trimipramine | 1980 |
41 other study(ies) available for imipramine and protriptyline
Article | Year |
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[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
2,4-Dihydro-3H-1,2,4-triazole-3-thiones as potential antidepressant agents.
Topics: Animals; Antidepressive Agents; Desipramine; gamma-Aminobutyric Acid; Male; Mice; Monoamine Oxidase Inhibitors; Norepinephrine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Triazoles | 1988 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.
Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cricetinae; Cricetulus; Drug Design; Humans; Imidazoles; Male; Models, Molecular; Motor Activity; Purines; Radioligand Assay; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triazoles | 2005 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship | 2008 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship | 2010 |
Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.
Topics: Animals; Antineoplastic Agents; Biological Availability; Cell Line; Drug Design; Enzyme Inhibitors; Humans; Immunologic Factors; Indoles; Kinetics; Mice; Neoplasms; Structure-Activity Relationship; Tryptophan Oxygenase | 2011 |
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
Topics: Animals; Area Under Curve; Humans; Intestinal Absorption; Ligands; Male; Metabolic Clearance Rate; Models, Chemical; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Pyrrolidinones; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship | 2013 |
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.
Topics: Acetamides; Allosteric Regulation; Animals; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism; Structure-Activity Relationship | 2013 |
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Drug Design; Epilepsy; Male; Mice; Microsomes, Liver; Molecular Structure; Pilocarpine | 2016 |
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship | 2017 |
Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain.
Topics: | 2022 |
Tricyclic antidepressants and histamine H1 receptors.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Atropine; Benztropine; Cells, Cultured; Clozapine; Cyproheptadine; Desipramine; Doxepin; Haloperidol; Histamine H1 Antagonists; Hydroxyzine; Imipramine; Mice; Neoplasms, Experimental; Neuroblastoma; Nortriptyline; Protriptyline; Receptors, Histamine; Receptors, Histamine H1; Receptors, Muscarinic | 1979 |
Interactions of tricyclic antidepressant drugs with deprivation-induced fluid consumption by rats.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Doxepin; Drinking Behavior; Fenclonine; Imipramine; Male; Methyltyrosines; Nortriptyline; Protriptyline; Rats; Water Deprivation | 1977 |
Regulation of prostaglandin metabolism: activation of 15-hydroxyprostaglandin dehydrogenase by chlorpromazine and imipramine related drugs.
Topics: Alcohol Oxidoreductases; Amitriptyline; Animals; Chlorpromazine; Desipramine; Dibenzocycloheptenes; Enzyme Activation; Hydroxyprostaglandin Dehydrogenases; Imipramine; Kidney; Kinetics; NAD; Protriptyline; Swine | 1976 |
Inhibition of rabbit monoamine oxidase by doxepin and related drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Blood Platelets; Chlorprothixene; Deamination; Depression, Chemical; Dibenzocycloheptenes; Doxepin; Humans; Hydrogen-Ion Concentration; Imipramine; Lung; Mitochondria; Monoamine Oxidase Inhibitors; Phenethylamines; Propylamines; Protriptyline; Rabbits; Serotonin | 1975 |
Metabolism of 5-hydroxytryptamine and levels of tricyclic antidepressant drugs in rat brain after acute and chronic treatment.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Desipramine; Drug Administration Schedule; Imipramine; Male; Probenecid; Protriptyline; Rats; Serotonin | 1977 |
A reward-reduction model of depression using self stimulating rats: an appraisal.
Topics: Amphetamine; Animals; Depression; Disease Models, Animal; Humans; Imipramine; Male; Protriptyline; Rats; Reward; Self Stimulation | 1979 |
Plasma levels of tricyclic antidepressants and clinical efficacy: review of the literature -- part II.
Topics: Antidepressive Agents, Tricyclic; Biotransformation; Clomipramine; Depression; Desipramine; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Doxepin; Drug Interactions; Humans; Imipramine; Maprotiline; Protriptyline | 1979 |
Assay of tricyclic structured drugs and their metabolites in urine by high-performance liquid chromatography.
Topics: Amitriptyline; Chlorpromazine; Chromatography, High Pressure Liquid; Dibenzocycloheptenes; Humans; Imipramine; Nortriptyline; Protriptyline | 1977 |
The separation of some tricyclic antidepressants by high-performance liquid chromatography.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Desipramine; Imipramine; Microchemistry; Nortriptyline; Protriptyline; Trimipramine | 1976 |
The relationship between hiatus hernia and tricyclic antidepressants: a report of five cases.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Esophagogastric Junction; Female; Gastroesophageal Reflux; Hernia, Diaphragmatic; Hernia, Hiatal; Humans; Imipramine; Male; Middle Aged; Muscle Tonus; Muscle, Smooth; Parasympatholytics; Protriptyline | 1975 |
Norepinephrine metabolism after short- and long-term administration of tricyclic antidepressant drugs and electroconvulsive shock.
Topics: Animals; Antidepressive Agents, Tricyclic; Depression, Chemical; Desipramine; Electroshock; Imipramine; Norepinephrine; Protriptyline; Rats; Time Factors | 1975 |
Ion pair chromatography of carboxylic acids. II. Use of N-methylimipramine as stationary phase.
Topics: Benzilates; Carboxylic Acids; Chromatography, Ion Exchange; Imipramine; Phenylbutyrates; Protriptyline; Salicylates | 1975 |
Genotoxicity evaluation of five tricyclic antidepressants in the wing somatic mutation and recombination test in Drosophila melanogaster.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; DNA; Dose-Response Relationship, Drug; Drosophila melanogaster; Imipramine; Mutagenicity Tests; Nortriptyline; Protriptyline; Recombination, Genetic | 1991 |
Antidepressants: their uses in nonpsychiatric disorders of aging.
Topics: Affective Symptoms; Aged; Antidepressive Agents; Chronic Disease; Colonic Diseases, Functional; Depression; Doxepin; Female; Humans; Imipramine; Male; Narcolepsy; Nomifensine; Pain; Peptic Ulcer; Protriptyline; Sleep Apnea Syndromes; Syndrome; Trimipramine; Urinary Incontinence | 1986 |
Preliminary clinical experience with imipramine HCl in the treatment of sleep apnea syndrome.
Topics: Adult; Body Weight; Female; Follow-Up Studies; Humans; Imipramine; Male; Middle Aged; Protriptyline; Sleep Apnea Syndromes | 1986 |
Effect of tricyclic antidepressant drugs on lymphocyte membrane structure.
Topics: Animals; Antidepressive Agents, Tricyclic; Cell Membrane; Cells, Cultured; Desipramine; Dose-Response Relationship, Drug; Fluorescent Dyes; Imipramine; Lymphocytes; Male; Mice; Nortriptyline; Protriptyline; Spleen; Temperature; Time Factors | 1984 |
Liquid chromatographic separation of antidepressant drugs: I. Tricyclics.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Promazine; Protriptyline | 1983 |
Tricyclic antidepressant drugs and individual differences in the exploratory activity of rats: contrasting effects of tertiary and secondary amine compounds.
Topics: Amines; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Exploratory Behavior; Female; Imipramine; Protriptyline; Rats; Structure-Activity Relationship | 1980 |
TCA-induced mania: differences between switchers and nonswitchers.
Topics: Adult; Affective Disorders, Psychotic; Age Factors; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Desipramine; Doxepin; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Protriptyline | 1982 |
The relationship of therapeutic response to antidepressant plasma levels: an update.
Topics: Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents; Biological Availability; Depressive Disorder; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Patient Compliance; Protriptyline | 1982 |
Liquid-chromatographic analysis for common tricyclic antidepressant drugs and their metabolites in serum or plasma with the technicon "FAST-LC" system.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Autoanalysis; Chromatography, High Pressure Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Protriptyline | 1981 |
Protriptyline and tinnitus.
Topics: Dibenzocycloheptenes; Female; Humans; Imipramine; Middle Aged; Protriptyline; Tinnitus | 1981 |
Hypomania and mania after withdrawal of tricyclic antidepressants.
Topics: Adult; Affective Disorders, Psychotic; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Female; Humans; Imipramine; Male; Protriptyline; Substance Withdrawal Syndrome | 1981 |
In pursuit of drugs for American trypanosomiasis: evaluation of some "standards" in a mouse model.
Topics: Animals; Antiprotozoal Agents; Chagas Disease; Disease Models, Animal; Female; Imipramine; Ketoconazole; Mice; Mice, Inbred Strains; Nifurtimox; Nigericin; Niridazole; Protriptyline; Trypanosoma cruzi | 1997 |
In vitro studies of DNA damage caused by tricyclic antidepressants: a role of peroxidase in the side effects of the drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cattle; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Horseradish Peroxidase; Hydrogen Peroxide; Hydrogen-Ion Concentration; Imipramine; Opipramol; Oxidation-Reduction; Protriptyline; Spectrophotometry, Ultraviolet | 2010 |