imipramine and propylthiouracil

imipramine has been researched along with propylthiouracil in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (35.00)	18.7374
1990's	1 (5.00)	18.2507
2000's	5 (25.00)	29.6817
2010's	7 (35.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bertolini, A; Marrama, D; Sandrini, M; Vergoni, AV	1
Biassoni, R; Vaccari, A	1
Belon, JP; Gaudel, G; Martin, P; Massol, J; Soubrié, P	1
Avni, J; Edelstein, EL; Khazan, N; Sulman, FG	1
Swartz, CM	1
FISCHER, R; GRIFFIN, F	1
FISCHETTI, B	1
LIPTON, MA; LOVE, GN; PRANGE, AJ	1
Amstislavskaya, TG; Kulikov, AV; Tikhonova, MA	1

Reviews

1 review(s) available for imipramine and propylthiouracil

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

19 other study(ies) available for imipramine and propylthiouracil

Article	Year
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Effects of thyroid status on the characteristics of alpha 1-, alpha 2-, beta, imipramine and GABA receptors in the rat brain. Life sciences, 1991, Volume: 48, Issue:7 Topics: Animals; Brain; Dihydroalprenolol; Hyperthyroidism; Hypothyroidism; Imipramine; Kinetics; Male; Muscimol; Organ Specificity; Prazosin; Propylthiouracil; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, GABA-A; Reference Values; Thyroid Gland; Triiodothyronine; Yohimbine	1991
Selective effects of thiol reagents on the binding sites for imipramine and neurotransmitter amines in the rat brain. British journal of pharmacology, 1985, Volume: 85, Issue:2 Topics: Animals; Brain; Carrier Proteins; Dithionitrobenzoic Acid; Dithiothreitol; Ethylmaleimide; Hydroxymercuribenzoates; Imipramine; Male; Mercaptoethanol; Methimazole; Propylthiouracil; Rats; Receptors, Dopamine; Receptors, Drug; Receptors, Neurotransmitter; Serotonin; Spiperone; Sulfhydryl Reagents	1985
Thyroid function and reversal by antidepressant drugs of depressive-like behavior (escape deficits) in rats. Neuropsychobiology, 1987, Volume: 18, Issue:1 Topics: Animals; Antidepressive Agents; Brain; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Escape Reaction; Hypothyroidism; Imipramine; Male; Nialamide; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroid Gland; Triiodothyronine	1987
Comparative study of imipramine, amitriptyline and their desmethyl analogues in the hypothyroid rat. Psychopharmacologia, 1967, Volume: 10, Issue:5 Topics: Amitriptyline; Animals; Blepharoptosis; Desipramine; Exploratory Behavior; Female; Hypothyroidism; Imipramine; Motor Activity; Nortriptyline; Posture; Propylthiouracil; Psychopharmacology; Rats; Sympathomimetics; Tetrabenazine	1967
Dependency of tricyclic antidepressant efficacy on thyroid hormone potentiation: case studies. The Journal of nervous and mental disease, 1982, Volume: 170, Issue:1 Topics: Adult; Depressive Disorder; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hyperthyroidism; Imipramine; Middle Aged; Propylthiouracil; Triiodothyronine	1982
QUININE DIMORPHISM: A CARDINAL DETERMINANT OF TASTE SENSITIVITY. Nature, 1963, Oct-26, Volume: 200 Topics: Acetates; Adolescent; Amides; Amphetamine; Amphetamines; Antithyroid Agents; Child; Chlorpromazine; Dextroamphetamine; Ergothioneine; Genetics, Medical; Humans; Imipramine; Methylene Blue; Pharmacology; Phenylalanine; Physiology; Propylthiouracil; Quinine; Sex; Sodium Chloride; Sucrose; Taste; Thioridazine; Triflupromazine; Urea	1963
[EXPERIMENTAL CONTRIBUTION TO THE STUDY OF THE MECHANISM OF THYROID ACTION OF VARIOUS PSYCHOACTIVE DRUGS. RESEARCH CONDUCTED ON THYROID IODINE UPTAKE IN VITRO]. Archivio italiano di scienze farmacologiche, 1963, Volume: 13 Topics: Animals; Chlorpromazine; Imipramine; In Vitro Techniques; Iodine; Iodine Isotopes; Perphenazine; Pharmacology; Propylthiouracil; Psychotropic Drugs; Research; Swine; Thyroid Function Tests; Thyroid Gland; Triflupromazine	1963
EFFECT OF ALTERED THYROID STATUS ON DESMETHYLIMIPRAMINE MORTALITY IN MICE. Nature, 1964, Dec-19, Volume: 204 Topics: Desipramine; Hyperthyroidism; Imipramine; Mice; Propylthiouracil; Research; Toxicology	1964
Chronic administration of imipramine normalizes decreased sexual motivation and increased predisposition to catalepsy induced by propylthiouracil in rats. Neuroscience and behavioral physiology, 2009, Volume: 39, Issue:4 Topics: Animals; Antidepressive Agents, Tricyclic; Antithyroid Agents; Catalepsy; Cerebral Cortex; Imipramine; Male; Propylthiouracil; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Sexual Behavior, Animal; Sexual Dysfunction, Physiological	2009