imipramine and promazine

imipramine has been researched along with promazine in 112 studies

Research

Studies (112)

TimeframeStudies, this research(%)All Research%
pre-199073 (65.18)18.7374
1990's4 (3.57)18.2507
2000's14 (12.50)29.6817
2010's20 (17.86)24.3611
2020's1 (0.89)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Chiang, GH; Unger, SH1
Pajeva, I; Wiese, M1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Duffy, EM; Jorgensen, WL1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Elshorst, B; Fiebig, K; Griesinger, C; Grimme, S; Jacobs, DM; Vogtherr, M; Zahn, R1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Kolaczkowska, A; Kolaczkowski, M; Michalak, K; Motohashi, N1
Andrisano, V; Barril, X; Bartolini, M; Carreiras, Mdo C; de los Ríos, C; García, AG; Huertas, O; León, R; López, B; López, MG; Luque, FJ; Marco-Contelles, J; Rodríguez-Franco, MI; Samadi, A; Villarroya, M1
Andrisano, V; Arce, MP; Badia, A; Bartolini, M; Camps, P; Clos, MV; Dafni, T; Formosa, X; Galdeano, C; Gómez, E; Huertas, O; Isambert, N; Lavilla, R; Luque, FJ; Mancini, F; Muñoz-Torrero, D; Ramírez, L; Rodríguez-Franco, MI1
Arce, MP; Conde, S; García, AG; González-Muñoz, GC; López, B; López, MG; Pérez, C; Rodríguez-Franco, MI; Villarroya, M1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Arce, MP; Conde, S; del Barrio, L; Egea, J; García, AG; González-Muñoz, GC; León, R; López, B; López, MG; Martín-de-Saavedra, MD; Pérez, C; Rodríguez-Franco, MI; Romero, A; Villarroya, M1
Chen, ZF; Huang, SL; Huang, ZS; Liang, H; Qin, JK; Tang, H; Zhao, HT; Zhao, LZ; Zhong, SM1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T1
Chen, ZF; Liang, H; Tang, H; Wang, ZY; Zhao, HT; Zhong, SM1
Bellman, K; Knegtel, RM; Settimo, L1
Andrisano, V; Bartolini, M; Clos, MV; Di Pietro, O; Juárez-Jiménez, J; Lavilla, R; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Ramón, R; Viayna, E; Vicente-García, E1
Clos, MV; Di Pietro, O; Espargaró, A; Juárez-Jiménez, J; Lavilla, R; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Sabaté, R1
Clos, MV; Di Pietro, O; Espargaró, A; Galdeano, C; Guillou, C; Lamuela-Raventós, RM; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Ragusa, IM; Sabaté, R; Vallverdú-Queralt, A; Viayna, E1
Artigas, A; Clos, MV; Gbedema, SY; Kelly, JM; Muñoz-Torrero, D; Pérez, B; Sola, I; Taylor, MC; Wright, CW1
Berenguer, D; Clos, MV; Di Pietro, O; Fisa, R; Kelly, JM; Lanzoni, A; Lavilla, R; Muñoz-Torrero, D; Pérez, B; Riera, C; Sayago, H; Sola, I; Taylor, MC; Viayna, E; Vicente-García, E1
Alencar, N; Di Pietro, O; Esteban, G; Juárez-Jiménez, J; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Sola, I; Solé, M; Szałaj, N; Unzeta, M; Vázquez, J; Viayna, E1
Artigas, A; Clos, MV; Kelly, JM; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Sola, I; Taylor, MC; Viayna, E; Wright, CW1
Chen, W; Huangli, Y; Qin, J; Shen, Y; Tang, H; Wang, L; Wei, S1
Arce, MP; Conde, S; Egea, J; Gil, C; León, R; López, MG; Monjas, L; Pérez, C; Rodríguez-Franco, MI; Villarroya, M1
Dolezal, R; Hepnarova, V; Hrabinova, M; Jost, P; Jun, D; Kaping, D; Kerhartova, M; Korabecny, J; Kuca, K; Kucera, T; Matouskova, L; Mezeiova, E; Muckova, L; Nepovimova, E; Pham, NL; Soukup, O; Spilovska, K; Staud, F; Vykoukalova, N1
Alcaro, S; Bagetta, D; Borges, F; Cagide, F; Oliveira, PJ; Ortuso, F; Pérez, C; Reis, J; Rodríguez-Franco, MI; Teixeira, J; Uriarte, E; Valencia, ME1
Andrisano, V; Barniol-Xicota, M; Bartolini, M; De Simone, A; Espargaró, A; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Pivetta, D; Pont, C; Sabate, R; Sureda, FX; Turcu, AL; Vázquez, S1
Brea, JM; Companys-Alemany, J; Griñán-Ferré, C; Johnson, JW; Kurnikova, MG; Loza, MI; Pallàs, M; Patel, DS; Pérez, B; Phillips, MB; Soto, D; Sureda, FX; Turcu, AL; Vázquez, S1
Gescher, A; Li Wan Po, A1
Løvstad, RA1
Kocher, R1
Keatinge, AM; Love, WC; Sinanan, K1
Horn, AS; Kennard, O; Post, ML1
Fletcher, HP; Schnell, RC; Wannarka, GL1
Förster, W; Jänicke, U1
Claeys, M; Maenhaut, W; Markey, SP1
Belvedere, G; Burti, L; Frigerio, A; Pantarotto, C1
Ferrari, C; Marmiroli, N; Puglisi, PP; Sabatini, MA; Tedeschi, F; Truzzi, G1
Bianchetti, L1
Frisk-Holmberg, M; van der Kleijn, E1
De Leenheer, A; Heyndrickx, A1
Dybing, E1
Tuomisto, J1
Baggiolini, M; Bickel, MH; Flückiger, M1
Glasser, H; Krieglstein, J1
Hackenberg, H; Krieglstein, J1
Krieglstein, J; Rieger, H; Stock, R1
Gabay, S; Huang, PC1
Gyermek, L; Hill, RT; Sigg, EB1
Brody, TM; Davis, PW1
Gabay, S; Harris, SR1
Colson, SH; Tolson, WW; Umberger, EJ1
Clark, B; Thompson, JW; Widdrington, G1
Horn, AS; Trace, RC1
Krieglstein, J; Rieger, H1
Turkington, RW1
Mainard, F; Stephan, Y; Welin, L2
Belvedere, G; De Nadai, F; Fanelli, R; Frigerio, A; Morselli, PL; Pantarotto, C; Riva, E1
Baker, GF; Rogers, HJ1
Chau-Wong, M; Seeman, P; Staiman, A1
Ahtee, L; Paasonen, MK1
Allikmets, L; Delgado, JM1
Allikmets, L; Delgado, JM; Richards, SA1
Ruutu, T1
Maickel, RP; Sokol, GH1
Trautmann, A1
Baum, T; Eckfeld, DK; Rowles, G; Shropshire, AT; Varner, LL1
Oates, JA; Shand, DG1
Ahonen, A; Pentilä, A1
Gross, R; Linker, H; Reuter, H1
Allikmets, LH; Lapin, IP; Vahing, VA1
Anton-Tay, F; Axelrod, J; Wurtman, RJ1
Ibrahim, I; Sulman, FG; Weller, CP1
Lippmann, W; Wishnick, M1
Beierle, FA; Hubbard, RW1
Dahlbom, R; Holmberg, B; Lindborg, B; Ross, SB1
Eandi, M; Ricci Gamalero, S1
Dumon-Radermecker, M; Van Sweden, B1
Daniel, WA; Wójcikowski, J2
Ballesta, J; de la Torre, R; González, S; Ortuño, J; Pascual, JA1
FRIED, E; IZQUIERDO, JA; VILALLONGA, F1
MARIANI, L1
BICKEL, MH; BRODIE, BB; SULSER, F1
HIMWICH, HE; STEINER, WG1
BEGHI, Q1
BIALY, HS; SEEMAN, PM1
GYERMEK, L; SIGG, EB; SOFFER, L1
DAUBY, J; GIURGEA, C; GIURGEA, M; LEVIS, S1
LEAU, O1
BOHACEK, N; HAJNSEK, F; SARTORIUS, N1
HELE, P1
BOFF, E; SCHECKEL, CL1
GITTELMAN, RK; KLEIN, DF; POLLACK, M1
MCCANCE, I1
LUDDEN, CT; PORTER, CC; STAVORSKI, JM; STONE, CA; TOTARO, JA1
DEITCHMAN, GL; FORREST, IS; QUESADA, F1
POLLACK, B2
HALLIWELL, G; QUINTON, RM; WILLIAMS, FE1
VAILLANT, GE1
Anjum, K; Khan, IA; Koya, PA1

Reviews

1 review(s) available for imipramine and promazine

ArticleYear
EFFECTS OF PSYCHOTROPIC DRUGS ON LONG-TERM ADJUSTMENT. A REVIEW.
    Psychopharmacologia, 1964, Apr-03, Volume: 5

    Topics: Chlorpromazine; Electroconvulsive Therapy; Hospitals, Psychiatric; Imipramine; Mental Disorders; Phenothiazines; Placebos; Promazine; Psychopharmacology; Psychotropic Drugs; Rehabilitation; Schizophrenia; Social Conditions

1964

Trials

1 trial(s) available for imipramine and promazine

ArticleYear
Prolactin secretion in patients treated with various drugs: phenothiazines, tricyclic antidepressants, reserpine, and methyldopa.
    Archives of internal medicine, 1972, Volume: 130, Issue:3

    Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Clinical Trials as Topic; Fluphenazine; Humans; Hypertension; Imipramine; Injections, Intramuscular; Methyldopa; Phenothiazines; Prolactin; Promazine; Reserpine; Stimulation, Chemical; Time Factors; Tranquilizing Agents

1972

Other Studies

110 other study(ies) available for imipramine and promazine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship

1981
Molecular modeling of phenothiazines and related drugs as multidrug resistance modifiers: a comparative molecular field analysis study.
    Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11

    Topics: Antineoplastic Agents; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Conformation; Phenothiazines; Thioxanthenes; Tumor Cells, Cultured

1998
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Antimalarial drug quinacrine binds to C-terminal helix of cellular prion protein.
    Journal of medicinal chemistry, 2003, Aug-14, Volume: 46, Issue:17

    Topics: Antimalarials; Binding Sites; Chloroquine; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Peptide Fragments; Phenothiazines; Prions; Protein Structure, Secondary; Quinacrine; Recombinant Proteins; Structure-Activity Relationship

2003
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
New high-throughput screening assay to reveal similarities and differences in inhibitory sensitivities of multidrug ATP-binding cassette transporters.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4

    Topics: Antifungal Agents; ATP-Binding Cassette Transporters; Fluphenazine; Fungal Proteins; Ketoconazole; Membrane Transport Proteins; Rhodamines; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2009
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.
    Journal of medicinal chemistry, 2009, May-14, Volume: 52, Issue:9

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Butyrylcholinesterase; Calcium; Calcium Channel Blockers; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytosol; Dihydropyridines; Humans; Hydrogen Peroxide; Kinetics; Ligands; Models, Molecular; Peptide Fragments; Permeability; Tacrine

2009
Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds.
    Journal of medicinal chemistry, 2009, Sep-10, Volume: 52, Issue:17

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Drug Design; Humans; Isomerism; Membranes, Artificial; Mice; Models, Molecular; Molecular Conformation; Permeability; Protein Binding; Tacrine

2009
Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease.
    Journal of medicinal chemistry, 2009, Nov-26, Volume: 52, Issue:22

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Catalytic Domain; Cattle; Cell Death; Cell Line, Tumor; Cell Survival; Cholinergic Agents; Cholinesterase Inhibitors; Esters; Glutamic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Neuroprotective Agents; Permeability; Piperidines; Protein Binding

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Agents; Butyrylcholinesterase; Calcium; Cell Death; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Okadaic Acid; Peptide Fragments; Phenothiazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured

2011
Hybrids of oxoisoaporphine-tacrine congeners: novel acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation inhibitors.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:10

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Aporphines; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Electrophorus; Horses; Humans; Models, Biological; Tacrine

2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics

2012
Novel oxoisoaporphine-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.
    Bioorganic & medicinal chemistry letters, 2012, Mar-15, Volume: 22, Issue:6

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Aporphines; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Humans; Membranes, Artificial; Models, Molecular; Molecular Structure; Permeability; Protein Binding

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
1,2,3,4-Tetrahydrobenzo[h][1,6]naphthyridines as a new family of potent peripheral-to-midgorge-site inhibitors of acetylcholinesterase: synthesis, pharmacological evaluation and mechanistic studies.
    European journal of medicinal chemistry, 2014, Feb-12, Volume: 73

    Topics: Acetylcholinesterase; Animals; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Electrophorus; Humans; Membranes, Artificial; Models, Biological; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Naphthyridines; Permeability; Protein Binding

2014
Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies.
    European journal of medicinal chemistry, 2014, Sep-12, Volume: 84

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Cholinesterase Inhibitors; Cholinesterases; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Naphthyridines; Structure-Activity Relationship; Tacrine; tau Proteins; Tauopathies

2014
Shogaol-huprine hybrids: dual antioxidant and anticholinesterase agents with β-amyloid and tau anti-aggregating properties.
    Bioorganic & medicinal chemistry, 2014, Oct-01, Volume: 22, Issue:19

    Topics: Acetylcholinesterase; Aminoquinolines; Amyloid beta-Peptides; Antioxidants; Catechols; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Heterocyclic Compounds, 4 or More Rings; Humans; Molecular Structure; Protein Aggregates; Protein Aggregation, Pathological; Structure-Activity Relationship; tau Proteins

2014
Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprines.
    Bioorganic & medicinal chemistry letters, 2014, Dec-01, Volume: 24, Issue:23

    Topics: Antimalarials; Antiprotozoal Agents; Humans; Molecular Structure; Structure-Activity Relationship

2014
Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity.
    European journal of medicinal chemistry, 2015, Nov-13, Volume: 105

    Topics: Acetylcholinesterase; Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electrophorus; Leishmania infantum; Molecular Structure; Parasitic Sensitivity Tests; Quinolines; Rats; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosoma cruzi

2015
Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors.
    Bioorganic & medicinal chemistry, 2016, 10-15, Volume: 24, Issue:20

    Topics: Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Structure-Activity Relationship

2016
Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents.
    Bioorganic & medicinal chemistry, 2016, 11-01, Volume: 24, Issue:21

    Topics: Aminoquinolines; Brain; Dose-Response Relationship, Drug; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei

2016
Multitarget-directed oxoisoaporphine derivatives: Anti-acetylcholinesterase, anti-β-amyloid aggregation and enhanced autophagy activity against Alzheimer's disease.
    Bioorganic & medicinal chemistry, 2016, 11-15, Volume: 24, Issue:22

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Aporphines; Autophagy; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Protein Aggregates; Structure-Activity Relationship; Tumor Cells, Cultured

2016
Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.
    European journal of medicinal chemistry, 2017, Apr-21, Volume: 130

    Topics: Alzheimer Disease; Animals; Brain Ischemia; Calcium Channel Blockers; Cholinesterase Inhibitors; Donepezil; Glutamates; Hippocampus; Humans; Indans; Neuroprotective Agents; Piperidines; Rats; Solid-Phase Synthesis Techniques

2017
The concept of hybrid molecules of tacrine and benzyl quinolone carboxylic acid (BQCA) as multifunctional agents for Alzheimer's disease.
    European journal of medicinal chemistry, 2018, Apr-25, Volume: 150

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cell Line; Cholinesterase Inhibitors; Cricetulus; Dose-Response Relationship, Drug; Humans; Molecular Structure; Quinolines; Structure-Activity Relationship; Tacrine

2018
Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors.
    European journal of medicinal chemistry, 2018, Oct-05, Volume: 158

    Topics: Alzheimer Disease; Blood-Brain Barrier; Cholinesterase Inhibitors; Cholinesterases; Chromones; Drug Design; Hep G2 Cells; Humans; Ligands; Molecular Docking Simulation; Molecular Targeted Therapy; Monoamine Oxidase; Monoamine Oxidase Inhibitors

2018
A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors.
    European journal of medicinal chemistry, 2019, Oct-15, Volume: 180

    Topics: Acetylcholinesterase; Adamantane; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Neuroprotective Agents; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Tacrine

2019
Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease.
    European journal of medicinal chemistry, 2022, Jun-05, Volume: 236

    Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Disease Models, Animal; Memantine; Mice; Receptors, N-Methyl-D-Aspartate

2022
Correlation of physicochemical properties with absorption and metabolism of some tricyclic drugs.
    The Journal of pharmacy and pharmacology, 1978, Volume: 30, Issue:6

    Topics: Absorption; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chlorpromazine; Doxepin; Imipramine; In Vitro Techniques; Male; Methylation; Phenothiazines; Promazine; Promethazine; Rats; Surface Tension

1978
Effect of centrally active drugs on dopamine oxidation by rat brain catecholamine oxidase.
    Experientia, 1979, Dec-15, Volume: 35, Issue:12

    Topics: Animals; Antipsychotic Agents; Brain; Chlorpromazine; Desipramine; Dopamine; Dopamine beta-Hydroxylase; Female; Haloperidol; Imipramine; Kinetics; Promazine; Rats; Thioridazine; Trifluoperazine; Trifluperidol

1979
[The treatment of chronic pain symptoms with psychotropic drugs (author's transl)].
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1976, Volume: 9, Issue:6

    Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bone Diseases; Clomipramine; Drug Therapy, Combination; Haloperidol; Humans; Imipramine; Neoplasms; Neuralgia; Pain; Palliative Care; Promazine; Trimipramine

1976
Effects of reserpine, chlorpromazine, imipramine and amitriptyline on urinary excretion of adenosine 3' 5' cyclic monophosphate in rats.
    Irish journal of medical science, 1975, Volume: 144, Issue:7

    Topics: Amitriptyline; Animals; Cyclic AMP; Imipramine; Male; Promazine; Rats; Reserpine

1975
Dopamine receptor blockade and the neuroleptics, a crystallographic study.
    The Journal of pharmacy and pharmacology, 1975, Volume: 27, Issue:8

    Topics: Chlorpromazine; Chlorprothixene; Crystallography; Dopamine Antagonists; Flupenthixol; Imipramine; Molecular Conformation; Phenothiazines; Promazine; Promethazine; Receptors, Drug; Structure-Activity Relationship; Thiethylperazine; Tranquilizing Agents; Triflupromazine

1975
Variations of chlorpromazine-related isosteres on the glycemic response in mice.
    General pharmacology, 1979, Volume: 10, Issue:3

    Topics: Adrenalectomy; Animals; Blood Glucose; Carbamazepine; Chlorpromazine; Clomipramine; Cyproheptadine; Hyperglycemia; Imipramine; Insulin; Islets of Langerhans; Male; Mice; Promazine

1979
Effects of imipramine, chlorpromazine and promazine pretreatment on the in vitro prostaglandin biosynthesis of rabbit brain and renal medulla.
    Pharmacological research communications, 1977, Volume: 9, Issue:5

    Topics: Animals; Brain; Chlorpromazine; Female; Hypnotics and Sedatives; Imipramine; In Vitro Techniques; Kidney; Kidney Medulla; Male; Promazine; Prostaglandins; Prostaglandins E; Prostaglandins F; Rabbits; Time Factors

1977
Variance analysis of error in selected ion monitoring assays using various internal standards. A practical study case.
    Biomedical mass spectrometry, 1977, Volume: 4, Issue:2

    Topics: Analysis of Variance; Chromatography, Gas; Desipramine; Imipramine; Maprotiline; Mass Spectrometry; Methods; Promazine; Regression Analysis; Time Factors

1977
Gas chromatographic-mass fragmentographic determation of "steady-state" plasma levels of imipramine and desipramine in chronically treated patients.
    Journal of chromatography, 1975, Sep-03, Volume: 111, Issue:2

    Topics: Chromatography, Gas; Depression; Desipramine; Dose-Response Relationship, Drug; Female; Gas Chromatography-Mass Spectrometry; Humans; Imipramine; Middle Aged; Promazine

1975
Relationship between growth inhibition and mitochondrial function in petite-negative yeasts. II. Effects of central nervous system drugs upon pathogenic and non-pathogenic Candida species.
    Biology of the cell, 1985, Volume: 53, Issue:1

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Candida; Cell Division; Chlorpheniramine; Chlorpromazine; Clomipramine; Cytochromes; Electrophoresis, Polyacrylamide Gel; Imipramine; Mitochondria; Oxygen Consumption; Promazine

1985
[Drug therapy of so-called postherpetic neuralgia, the only valid alternative. Clinical experience in 43 treated cases].
    Minerva medica, 1986, Jan-14, Volume: 77, Issue:1-2

    Topics: Administration, Oral; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Drug Therapy, Combination; Electric Stimulation Therapy; Herpes Zoster; Humans; Imipramine; Middle Aged; Neuralgia; Promazine

1986
The relationship between the lipophilic nature of tricyclic neuroleptics and antidepressants, and histamine release.
    European journal of pharmacology, 1972, Volume: 18, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Chlorpromazine; Chlorprothixene; Clopenthixol; Desipramine; Fluphenazine; Histamine Release; Imipramine; Kinetics; Male; Mast Cells; Methotrimeprazine; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Rats; Solvents; Structure-Activity Relationship; Thioridazine; Tranquilizing Agents; Trifluoperazine

1972
Identification of phenothiazine derivatives and analogs by x-ray diffraction. II. Active substances in pharmaceutical formulations.
    Journal - Association of Official Analytical Chemists, 1971, Volume: 54, Issue:3

    Topics: Amitriptyline; Chlorprothixene; Crystallization; Dibenzazepines; Fluphenazine; Imipramine; Methods; Methotrimeprazine; Nortriptyline; Opipramol; Perphenazine; Phenothiazines; Picrates; Prochlorperazine; Promazine; Promethazine; Quaternary Ammonium Compounds; Thioridazine; Triflupromazine; X-Ray Diffraction

1971
Effects of membrane stabilizers on glucuronidation and amino acid transport in cultures of rat hepatoma cells.
    Acta pharmacologica et toxicologica, 1973, Volume: 32, Issue:6

    Topics: Alanine; Aminoisobutyric Acids; Animals; Antipsychotic Agents; Biological Transport; Carcinoma, Hepatocellular; Cell Membrane; Cells, Cultured; Depression, Chemical; Glucuronates; Imipramine; Liver Neoplasms; Promazine; Propranolol; Protein Binding; Rats; Thioridazine

1973
A new modification for studying 5-HT uptake by blood platelets: a re-evaluation of tricyclic antidepressants as uptake inhibitors.
    The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:2

    Topics: Amitriptyline; Animals; Blood Platelets; Carbon Radioisotopes; Chlorpromazine; Desipramine; Dibenzazepines; Doxepin; Imipramine; In Vitro Techniques; Kinetics; Models, Biological; Nortriptyline; Promazine; Rabbits; Serotonin; Synaptosomes; Temperature; Trifluoperazine; Triflupromazine

1974
[Comparative demethylation of tricyclic psychotropic drugs by rat liver microsomes].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1967, Volume: 256, Issue:3

    Topics: Animals; Antidepressive Agents; Chlorprothixene; Imipramine; Liver; Male; Microsomes; Promazine; Rats; Thioridazine; Trifluoperazine

1967
[Protein binding of some psychoactive drugs with a tricyclic ring system, as a function of their chemical constitution].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 265, Issue:4

    Topics: Acepromazine; Alcohols; Amitriptyline; Chemical Phenomena; Chemistry, Physical; Chlorpromazine; Chromatography, Gel; Desipramine; Dialysis; Dibenzazepines; Dibenzocycloheptenes; Imipramine; Phenothiazines; Promazine; Protein Binding; Serum Albumin, Bovine; Thiazines; Triflupromazine

1970
Comparative study on the inhibition of Na + , K + -activated ATPase activity by chlorpromazine, promazine, imipramine, and their monodesmethyl metabolites.
    Naunyn-Schmiedeberg's archives of pharmacology, 1972, Volume: 274, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Brain; Chlorpromazine; Enzyme Activation; Female; Imipramine; Methylation; Microsomes; Potassium; Promazine; Protein Binding; Rats; Receptors, Drug; Sodium

1972
Influence of therapeutic and toxic doses of neuroleptics and antidepressants on energy metabolism of the isolated perfused rat brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 279, Issue:3

    Topics: Acetone; Ammonia; Animals; Antidepressive Agents; Brain; Creatine; Desipramine; Dose-Response Relationship, Drug; Electroencephalography; Energy Metabolism; Fructosephosphates; Glucose; Glucosephosphates; Glycolysis; Imipramine; Ketoglutaric Acids; Lactates; Male; Organophosphorus Compounds; Perfusion; Phosphocreatine; Promazine; Pyruvates; Rats; Ribonucleotides; Tranquilizing Agents; Trioses

1973
Isolation and characterization of phenothiazine-copper complexes.
    Advances in biochemical psychopharmacology, 1974, Volume: 9, Issue:0

    Topics: Chemical Phenomena; Chemistry; Chlorpromazine; Copper; Electron Spin Resonance Spectroscopy; Fluphenazine; Free Radicals; Hydrogen-Ion Concentration; Imipramine; Kinetics; Mass Spectrometry; Methods; Phenothiazines; Potassium Chloride; Promazine; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Sulfoxides

1974
Antagonism to reserpine induced depression by imipramine, related psychoactive drugs, and some autonomic agents.
    Psychopharmacologia, 1965, Feb-15, Volume: 7, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Behavior, Animal; Cyproheptadine; Desipramine; Diphenhydramine; Hallucinogens; Histamine H1 Antagonists; Imipramine; Lysergic Acid Diethylamide; Mice; Promazine; Psychopharmacology; Reserpine; Serotonin

1965
Inhibition of Na+K+-activated adenosine triphosphatase activity in rat brain by substituted phenothiazines.
    Biochemical pharmacology, 1966, Volume: 15, Issue:6

    Topics: Adenosine Triphosphatases; Aminobutyrates; Animals; Brain; Chlorpromazine; Dextroamphetamine; Fluphenazine; Imipramine; In Vitro Techniques; Microsomes; Pentobarbital; Pentylenetetrazole; Perphenazine; Phenothiazines; Potassium; Prochlorperazine; Promazine; Promethazine; Rats; Sodium; Strychnine; Thiethylperazine; Thioridazine; Trifluoperazine; Triflupromazine

1966
Studies of flavin-adenine dinucleotide-requiring enzymes and phenothiazines. 3. Inhibition kinetics with highly purified D-amino acid oxidase.
    Biochemical pharmacology, 1967, Volume: 16, Issue:5

    Topics: Animals; Chlorpromazine; Chlorprothixene; D-Amino-Acid Oxidase; Fluphenazine; Imipramine; Kinetics; Perphenazine; Phenothiazines; Promazine; Promethazine; Swine; Thioridazine; Trifluoperazine; Triflupromazine; Trimeprazine; Ultracentrifugation

1967
The effects of some centrally acting drugs on the glucocorticoid induction of hepatic tyrosine transaminase.
    Life sciences, 1969, Nov-15, Volume: 8, Issue:22

    Topics: Adrenalectomy; Amitriptyline; Animals; Chlorpheniramine; Chlorpromazine; Desipramine; Diphenhydramine; Enzyme Induction; Female; Fluocinolone Acetonide; Fluorometholone; Glucocorticoids; Hydrocortisone; Imipramine; Liver; Male; Prednisone; Proadifen; Promazine; Promethazine; Rats; Reserpine; Sex Factors; Triflupromazine; Tyrosine Transaminase

1969
Analysis of the inhibition of pethidine N-demethylation by monoamine oxidase inhibitors and some other drugs with special reference to drug interactions in man.
    British journal of pharmacology, 1972, Volume: 44, Issue:1

    Topics: Amphetamine; Animals; Chlorpromazine; Desipramine; Drug Interactions; Histamine; Hydrazines; Hydrocortisone; Imipramine; Iproniazid; Male; Meperidine; Methylation; Microsomes, Liver; Monoamine Oxidase Inhibitors; Nialamide; Opipramol; Phenothiazines; Phenylhydrazines; Prednisolone; Proadifen; Promazine; Rats; Transferases

1972
Structure-activity relations for the inhibition of 5-hydroxytryptamine uptake by tricyclic antidepressants into synaptosomes from serotoninergic neurones in rat brain homogenates.
    British journal of pharmacology, 1974, Volume: 51, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Brain Chemistry; Chlorpromazine; Hypothalamus; Imipramine; In Vitro Techniques; Iprindole; Methylation; Neurons; Nortriptyline; Promazine; Rats; Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Synaptosomes

1974
Quantitative analysis of the EEG effects produced by imipramine, desipramine promazine, and monodesmethyl promazine in the isolated perfused rat brain.
    Psychopharmacologia, 1974, Volume: 39, Issue:2

    Topics: Analysis of Variance; Animals; Brain; Desipramine; Electroencephalography; Imipramine; In Vitro Techniques; Male; Perfusion; Promazine; Rats

1974
[Cerebral and hepatic fixation of phenothiazine and iminodibenzyl derivatives in rats].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1972, Sep-04, Volume: 275, Issue:10

    Topics: Animals; Blood Proteins; Blood-Brain Barrier; Brain Chemistry; Chlorpromazine; Imipramine; Injections, Intraperitoneal; Liver; Prochlorperazine; Promazine; Protein Binding; Rats

1972
A method for the determination of imipramine in human plasma by gas-liquid chromatography-mass fragmentography.
    Journal of chromatography, 1972, Dec-20, Volume: 74, Issue:2

    Topics: Chromatography, Gas; Humans; Imipramine; Mass Spectrometry; Methods; Microchemistry; Promazine

1972
Effects of psychotropic drugs on the erythrocyte permeability to glucose and ethylidene glucose.
    Biochemical pharmacology, 1972, Jul-01, Volume: 21, Issue:13

    Topics: Barbiturates; Cell Membrane Permeability; Chlorpromazine; Erythrocytes; Ethylenes; Fluorine; Glucose; Haloperidol; Humans; Imipramine; Mathematics; Nitrobenzenes; Prochlorperazine; Promazine; Promethazine; Temperature; Thiopental; Trifluoperazine

1972
The nerve impulse-blocking actions of tranquilizers and the binding of neuroleptics to synaptosome membranes.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 190, Issue:1

    Topics: Animals; Axons; Brain; Calcium; Chlorpromazine; Haloperidol; Imipramine; In Vitro Techniques; Nerve Block; Neural Conduction; Phrenic Nerve; Promazine; Promethazine; Rats; Reserpine; Sciatic Nerve; Sulfur Radioisotopes; Synaptosomes; Thioridazine; Time Factors; Tranquilizing Agents; Trifluperidol; Tritium

1974
The haemolytic effect of some phenothiazine derivatives.
    Annales medicinae experimentalis et biologiae Fenniae, 1965, Volume: 43, Issue:2

    Topics: Animals; Anticoagulants; Blood Platelets; Cell Membrane Permeability; Chlorpromazine; Citrates; Colorimetry; Edetic Acid; Erythrocytes; Hemolysis; Imipramine; In Vitro Techniques; Phenothiazines; Promazine; Promethazine; Rabbits; Reserpine; Serotonin; Sodium Chloride; Surface-Active Agents; Tetrabenazine

1965
Injection of antidepressants in the amygdala of awake monkeys.
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 175, Issue:1

    Topics: Amitriptyline; Amygdala; Animals; Antidepressive Agents; Chlorprothixene; Electric Stimulation; Electroencephalography; Haplorhini; Imipramine; Injections; Procaine; Promazine

1968
Intra-mesencephalic injection of imipramine, promazine and chlorprothixene in awake monkeys.
    International journal of neuropharmacology, 1968, Volume: 7, Issue:3

    Topics: Animals; Attention; Chlorprothixene; Electric Stimulation; Haplorhini; Imipramine; Injections; Mesencephalon; Motor Activity; Procaine; Promazine; Social Behavior; Tectum Mesencephali

1968
[Binding to human serum proteins of drugs belonging to phenothiazine series, iminodibenzyle, thioxanthene and thiophenylpyridylamine].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1971, Mar-08, Volume: 272, Issue:10

    Topics: Antidepressive Agents; Blood Proteins; Chemical Phenomena; Chemistry; Chlorpromazine; Chlorprothixene; Chromatography, Gel; Desipramine; Dibenzazepines; Humans; Imipramine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Protein Binding; Spectrophotometry; Thiazines; Trimeprazine

1971
Effect of phenothiazines and related compounds on phagocytosis and bacterial killing by human neutrophilic leukocytes.
    Annales medicinae experimentalis et biologiae Fenniae, 1972, Volume: 50, Issue:1

    Topics: Amitriptyline; Antidepressive Agents; Blood Bactericidal Activity; Cell Membrane Permeability; Cell Survival; Chlorpromazine; Culture Media; Humans; Imipramine; Methods; Neutrophils; Phagocytosis; Phenothiazines; Promazine; Promethazine; Staphylococcus; Stimulation, Chemical; Structure-Activity Relationship; Sulfoxides

1972
Toxic interactions of d-amphetamine and tricyclic antidepressants in mice.
    Research communications in chemical pathology and pharmacology, 1972, Volume: 3, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Dextroamphetamine; Drug Antagonism; Drug Interactions; Drug Synergism; Imipramine; Injections, Intraperitoneal; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Nortriptyline; Promazine; Time Factors

1972
[Dialysis of drugs and poisons. 2].
    Medizinische Klinik, 1972, Nov-03, Volume: 67, Issue:44

    Topics: Acetaminophen; Aminopyrine; Amitriptyline; Aspirin; Carbamazepine; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Heroin; Humans; Imipramine; Lithium; Pargyline; Pentazocine; Phenacetin; Phenelzine; Phenytoin; Poisoning; Primidone; Promazine; Renal Dialysis; Salicylates; Tranylcypromine; Trifluoperazine

1972
Observations on models used for the evaluation of antiarrhythmic drugs.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 193, Issue:1

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atropine; Benzazepines; Bretylium Compounds; Chlorpheniramine; Diazepam; Disease Models, Animal; Dogs; Drug Antagonism; Guinea Pigs; Imipramine; Ketones; Lidocaine; Male; Meperidine; Mephentermine; Ouabain; Phentolamine; Phenytoin; Procainamide; Promazine; Promethazine; Propranolol; Quinidine

1971
Metabolism of propranolol by rat liver microsomes and its inhibition by phenothiazine and tricyclic antidepressant drugs.
    Biochemical pharmacology, 1971, Volume: 20, Issue:7

    Topics: Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Desipramine; Imipramine; Kinetics; Liver; Male; Metabolism; Microsomes, Liver; NAD; NADP; Nitrogen; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Propranolol; Rats; Subcellular Fractions; Trifluoperazine; Triflupromazine

1971
Effect of some drugs on the uptake of monoamines and their precursors in the mouse Paneth cells.
    Acta physiologica Scandinavica, 1971, Volume: 82, Issue:1

    Topics: 5-Hydroxytryptophan; Amines; Amitriptyline; Amphetamine; Animals; Binding Sites; Catecholamines; Chlorpromazine; Cocaine; Colon; Cytoplasmic Granules; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Duodenum; Female; Guanethidine; Ileum; Imipramine; Jejunum; Male; Methyltyrosines; Mice; Microscopy, Fluorescence; Nortriptyline; Pargyline; Peptide Biosynthesis; Promazine; Reserpine; Serotonin; Tyrosine

1971
[A possible mechanism of disaggregation of ADP-induced aggregates by imipramin and structurally related compouds].
    Thrombosis et diathesis haemorrhagica, 1969, Nov-15, Volume: 22, Issue:2

    Topics: Adenine Nucleotides; Amitriptyline; Blood Platelets; Chlorpromazine; Desipramine; Diphenhydramine; Humans; Imipramine; Nortriptyline; Optical Rotatory Dispersion; Platelet Adhesiveness; Promazine; Promethazine

1969
Dissimilar influences of imipramine, benactyzine and promazine on effects of micro-injections of noradrenaline, acetylcholine and serotonin into the amygdala in the cat.
    Psychopharmacologia, 1969, Volume: 15, Issue:5

    Topics: Acetylcholine; Aggression; Amygdala; Animals; Attention; Behavior, Animal; Benactyzine; Cats; Electroencephalography; Exploratory Behavior; Female; Humans; Imipramine; Injections; Male; Norepinephrine; Promazine; Salivation; Seizures; Serotonin; Sleep; Vomiting

1969
Inhibition of the metabolism of H3-melatonin by phenothiazines.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 161, Issue:2

    Topics: Amphetamine; Animals; Antimetabolites; Body Temperature; Brain; Chlorpromazine; Depression, Chemical; Desipramine; Female; Imipramine; Liver; Melatonin; Phenobarbital; Phenothiazines; Promazine; Promethazine; Rats; Tritium

1968
Analgesic profile of tranquillizers in multiple screening tests in mice.
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 176, Issue:1

    Topics: Acetaminophen; Aminopyrine; Analgesics; Animals; Aspirin; Chlorpromazine; Codeine; Diazepam; Diphenhydramine; Electric Stimulation; Haloperidol; Hot Temperature; Hydroxyzine; Imipramine; Isocarboxazid; Male; Meprobamate; Mice; Morphine; Perphenazine; Phenobarbital; Phenothiazines; Promazine; Promethazine; Reserpine; Tetrabenazine; Thiopental; Time Factors; Tranquilizing Agents

1968
Effects of methotrimeprazine, other phenothiazines and related compounds on the levels of norepinephrine in the mouse heart.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 157, Issue:2

    Topics: Amitriptyline; Animals; Catechols; Chlorpromazine; Hypnotics and Sedatives; Imipramine; In Vitro Techniques; Iproniazid; Male; Mice; Myocardium; Norepinephrine; Perphenazine; Phenothiazines; Proadifen; Prochlorperazine; Promazine; Trifluoperazine; Trimeprazine; Tritium

1967
Liquid chromatographic separation of antidepressant drugs: I. Tricyclics.
    Therapeutic drug monitoring, 1983, Volume: 5, Issue:3

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Promazine; Protriptyline

1983
Cyclizing compounds. V. Tertiary haloalkylamine derivatives related to the tricyclic psychopharmacological agents promazine, imipramine and amitriptyline.
    Acta pharmaceutica Suecica, 1984, Volume: 21, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain Chemistry; Chemical Phenomena; Chemistry; Imipramine; Male; Mice; Promazine

1984
[Evaluation in vitro of the local anesthetic effect by means of the dose/stabilization effect curve].
    Bollettino della Societa italiana di biologia sperimentale, 1980, Jan-15, Volume: 56, Issue:1

    Topics: Anesthetics, Local; Animals; Dose-Response Relationship, Drug; Imipramine; In Vitro Techniques; Lidocaine; Nerve Block; Procaine; Promazine; Rana pipiens; Sciatic Nerve

1980
The EEG in chronic psychotropic drug intoxications.
    Clinical EEG (electroencephalography), 1982, Volume: 13, Issue:4

    Topics: Adult; Aged; Amitriptyline; Chlorpromazine; Chlorprothixene; Chronic Disease; Drug Therapy, Combination; Electroencephalography; Evoked Potentials; Female; Humans; Imipramine; Lithium; Male; Perazine; Promazine; Promethazine; Psychoses, Substance-Induced; Psychotic Disorders; Psychotropic Drugs; Tropanes

1982
Contribution of lysosomal trapping to the total tissue uptake of psychotropic drugs.
    Pharmacology & toxicology, 1997, Volume: 80, Issue:2

    Topics: 1-Naphthylamine; Amitriptyline; Ammonium Chloride; Animals; Antidepressive Agents, Tricyclic; Carbamazepine; Drug Interactions; Fluoxetine; Imipramine; Lysosomes; Male; Monensin; Phospholipids; Promazine; Psychotropic Drugs; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Sertraline; Tissue Distribution

1997
Interactions between promazine and antidepressants at the level of cellular distribution.
    Pharmacology & toxicology, 1997, Volume: 81, Issue:6

    Topics: 1-Naphthylamine; Amitriptyline; Ammonium Chloride; Animals; Antidepressive Agents; Antipsychotic Agents; Carbamazepine; Drug Interactions; Fluoxetine; Hydrogen-Ion Concentration; Imipramine; Lysosomes; Male; Promazine; Rats; Rats, Wistar; Sertraline

1997
Quantitative determination of tricyclic antidepressants and their metabolites in plasma by solid-phase extraction (Bond-Elut TCA) and separation by capillary gas chromatography with nitrogen-phosphorous detection.
    Therapeutic drug monitoring, 1998, Volume: 20, Issue:3

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Desipramine; Drug Monitoring; Humans; Imipramine; Linear Models; Nortriptyline; Promazine; Sensitivity and Specificity

1998
Promazine, promethazine, diethazine and imipramine at the air- 0.1 M HCl interface.
    Archives internationales de pharmacodynamie et de therapie, 1961, Mar-01, Volume: 130

    Topics: Imipramine; Parasympatholytics; Phenothiazines; Promazine; Promethazine; Psychopharmacology

1961
[Drugs antagonistic to bradykinin].
    Bollettino della Societa italiana di biologia sperimentale, 1961, Dec-31, Volume: 37

    Topics: Anti-Allergic Agents; Atropine; Bradykinin; Chlorpromazine; Ergotamine; Histamine H1 Antagonists; Imipramine; Lysergic Acid Diethylamide; Papaverine; Phenylbutazone; Promazine; Promethazine

1961
Conversion of transquilizers to antidepressants by removal of one N-methyl group.
    Life sciences (1962), 1963, Volume: 4

    Topics: Antidepressive Agents; Imipramine; Promazine; Tranquilizing Agents

1963
EFFECTS OF ANTIDEPRESSANT DRUGS ON LIMBIC STRUCTURES OF RABBIT.
    The Journal of nervous and mental disease, 1963, Volume: 137

    Topics: Amitriptyline; Animals; Antidepressive Agents; Central Nervous System; Chlorpromazine; Chlorprothixene; Electroencephalography; Humans; Imipramine; Limbic System; Nervous System; Phenothiazines; Promazine; Rabbits; Research; Tranquilizing Agents; Trifluoperazine

1963
[PSYCHIATRIC USE OF SOME PSYCHOPHARMACOLOGICAL DRUGS IN PREGNANCY].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1963, Jun-30, Volume: 87

    Topics: Chlordiazepoxide; Chlorpromazine; Fetus; Haloperidol; Imipramine; Isocarboxazid; Meprobamate; Nialamide; Orphenadrine; Perphenazine; Pharmacology; Pregnancy; Prochlorperazine; Promazine; Psychopharmacology; Reserpine; Thalidomide; Thioridazine

1963
THE SURFACE ACTIVITY OF TRANQUILIZERS.
    Biochemical pharmacology, 1963, Volume: 12

    Topics: Antipsychotic Agents; Chlordiazepoxide; Chlorpromazine; Fluphenazine; Imipramine; Pharmacology; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Research; Reserpine; Surface Tension; Thioridazine; Tranquilizing Agents; Trifluoperazine; Triflupromazine; Trimeprazine

1963
INFLUENCE OF IMIPRAMINE AND RELATED PSYCHOACTIVE AGENTS ON THE EFFECT OF 5-HYDROXYTRYPTAMINE AND CATECHOLAMINES ON THE CAT NICTITATING MEMBRANE.
    The Journal of pharmacology and experimental therapeutics, 1963, Volume: 142

    Topics: Amitriptyline; Animals; Antidepressive Agents; Catecholamines; Cats; Chlorpromazine; Chlorprothixene; Desipramine; Epinephrine; Imipramine; Nictitating Membrane; Norepinephrine; Pharmacology; Promazine; Psychotropic Drugs; Research; Serotonin; Tranquilizing Agents

1963
[A MODIFIED ANTI-TETRABENAZINE TEST FOR SCREENING ANTIDETRESSIVE DRUGS].
    Medicina experimentalis : International journal of experimental medicine, 1963, Volume: 9

    Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Dextroamphetamine; Imipramine; Iproniazid; Mice; Nialamide; Pharmacology; Promazine; Rats; Research; Tetrabenazine

1963
[RELATION BETWEEN BLOOD CONCENTRATION AND THERAPEUTIC ACTION].
    La Presse medicale, 1963, Oct-12, Volume: 71

    Topics: Amidines; Anti-Bacterial Agents; Blood Chemical Analysis; Chlorpromazine; Chlorprothixene; Drug Therapy; Erythromycin; Imipramine; Oleandomycin; Penicillins; Promazine; Promethazine; Quinolines; Spiramycin; Stilbamidines; Suramin; Tetracycline; Tranquilizing Agents

1963
[EXTRAPYRAMIDAL SYMPTOMS DUE TO THE USE OF PSYCHOPHARMACA].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1963, Volume: 31

    Topics: Chlorpromazine; Chlorprothixene; Extrapyramidal Tracts; Fluphenazine; Imipramine; Methotrimeprazine; Monoamine Oxidase Inhibitors; Parkinsonian Disorders; Phenothiazines; Prochlorperazine; Promazine; Psychopharmacology; Rauwolfia; Sympathomimetics; Thioridazine; Toxicology; Tranquilizing Agents; Trifluoperazine

1963
THE INTERACTION OF PHENOTHIAZINE DERIVATIVES AND IMIPRAMINE WITH POLYPHOSPHATES OF BIOLOGICAL INTEREST.
    Biochimica et biophysica acta, 1963, Dec-20, Volume: 76

    Topics: Antipsychotic Agents; Chlorpromazine; Imipramine; Lithium; Pharmacology; Phenothiazines; Phosphates; Polyphosphates; Potassium; Promazine; Promethazine; Research; Sodium Chloride; Trifluoperazine

1963
BEHAVIORAL EFFECTS OF INTERACTING IMIPRAMINE AND OTHER DRUGS WITH D-AMPHETAMINE, COCAINE, AND TETRABENAZINE.
    Psychopharmacologia, 1964, Feb-12, Volume: 5

    Topics: Amitriptyline; Atropine; Avoidance Learning; Chlorpromazine; Cocaine; Desipramine; Dextroamphetamine; Guanethidine; Imipramine; Iproniazid; Isocarboxazid; Methylphenidate; Parasympatholytics; Pharmacology; Piperidines; Promazine; Promethazine; Rats; Research; Scopolamine; Tetrabenazine; Trihexyphenidyl; Tyramine

1964
STUDIES OF POTENTIATION OF HEXOBARBITONE INFUSED INTRAVENOUSLY.
    Archives internationales de pharmacodynamie et de therapie, 1964, Mar-01, Volume: 148

    Topics: Anesthesia; Anesthesia, Intravenous; Anti-Anxiety Agents; Anticonvulsants; Atropine; Benactyzine; Carbamates; Carisoprodol; Chlorpromazine; Chlorprothixene; Hexobarbital; Hydroxyzine; Hypnotics and Sedatives; Imipramine; Infusions, Parenteral; Meprobamate; Mice; Pharmacology; Phenothiazines; Promazine; Research; Serotonin; Thalidomide; Tranquilizing Agents

1964
ANTAGONISM OF CERTAIN EFFECTS OF CATECHOLAMINE-DEPLETING AGENTS BY ANTIDEPRESSANT AND RELATED DRUGS.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 144

    Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Catecholamines; Chlorpromazine; Cocaine; Desipramine; Dogs; Dopamine; Electric Stimulation; Electrophysiology; Guanethidine; Imipramine; Metaraminol; Methylphenidate; Mice; Myocardium; Nictitating Membrane; Norepinephrine; Pharmacology; Piperidines; Promazine; Research; Reserpine; Tripelennamine; Tyrosine

1964
UNICELLULAR ORGANISMS AS MODEL SYSTEMS FOR THE MODE OF ACTION OF PHENOTHIAZINE AND RELATED DRUGS.
    Proceedings of the Western Pharmacology Society, 1964, Volume: 7

    Topics: Cell Division; Cell Membrane Permeability; Chlordiazepoxide; Chlorpromazine; Chlorprothixene; Cysteine; Imipramine; Metabolism; Pharmacology; Phenothiazines; Promazine; Promethazine; Research; Saccharomyces; Tetrahymena; Thioridazine; Triflupromazine

1964
REPORT OF AN UNUSUALLY LARGE DOSAGE OF METHYLPHENIDATE HYDROCHLORIDE.
    The American journal of psychiatry, 1964, Volume: 121

    Topics: Alcoholic Beverages; Benactyzine; Depression; Depressive Disorder; Imipramine; Meprobamate; Methylphenidate; Pharmacology; Promazine; Toxicology

1964
A COMPARISON OF IMIPRAMINE, CHLORPROMAZINE AND RELATED DRUGS IN VARIOUS TESTS INVOLVING AUTONOMIC FUNCTIONS AND ANTAGONISM OF RESERPINE.
    British journal of pharmacology and chemotherapy, 1964, Volume: 23

    Topics: Alcoholic Intoxication; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Autonomic Nervous System; Bradycardia; Central Nervous System Stimulants; Chlorpromazine; Chlorprothixene; Desipramine; Dogs; Epinephrine; Imipramine; Mice; Norepinephrine; Pharmacology; Promazine; Rats; Research; Reserpine; Sleep; Toxicology; Tranquilizing Agents; Vasomotor System; Yohimbine

1964
A COMPARISON OF CHLORPROMAZINE AND IMIPRAMINE ON BEHAVIOR OF THE PIGEON.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 146

    Topics: Animals; Behavior, Animal; Birds; Chlorpromazine; Columbidae; Discrimination Learning; Imipramine; Methamphetamine; Pentobarbital; Promazine; Psychopharmacology; Research; Scopolamine

1964
Imipramine-promazine therapy for depression.
    The American journal of psychiatry, 1962, Volume: 118

    Topics: Depression; Depressive Disorder; Imipramine; Promazine

1962
Effect of inorganic salts on the clouding behavior of hydroxypropyl methyl cellulose in presence of amphiphilic drugs.
    Colloids and surfaces. B, Biointerfaces, 2013, Mar-01, Volume: 103

    Topics: Anions; Hypromellose Derivatives; Ibuprofen; Imipramine; Methylcellulose; Micelles; Models, Molecular; Pharmaceutical Preparations; Promazine; Salts; Solutions; Surface-Active Agents; Thermodynamics

2013