imipramine and procaine

imipramine has been researched along with procaine in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199023 (63.89)18.7374
1990's0 (0.00)18.2507
2000's6 (16.67)29.6817
2010's5 (13.89)24.3611
2020's2 (5.56)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Duffy, EM; Jorgensen, WL1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Caron, G; Ermondi, G1
Ahman, M; Holmén, AG; Wan, H1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Gozalbes, R; Pineda-Lucena, A1
Bellman, K; Knegtel, RM; Settimo, L1
Bajusz, D; Balogh, GT; Dargó, G; Müller, J; Simon, K1
Bach, A; Brambilla, R; Carmona, RMC; Desu, HL; Gajhede, M; Garcia, AD; Høj, LJ; Johansen, TN; Marseglia, G; Munafò, F; Narayanan, D; Pallesen, JS; Popowicz, GM; Sattler, M; Solbak, SMØ; Sørensen, LME; Tran, KT1
Meltzer, HY1
Allan, D; Michell, RH1
Gianturco, D; Pfieffer, E; Zung, WW1
Meltzer, HY; Stahl, SM1
Enyeart, JJ; Hinkle, PM; Phillips, WJ1
Luly, P; Pacini, L; Spinedi, A1
White, JM1
Bianchine, JR; Gerber, MC; Gerber, N; Tejwani, GA1
Kaniike, K; Kurogochi, Y1
Chang, CC; Chuang, ST1
Auclair, MC; Gulda, O; Lechat, P1
Oldendorf, WH1
Chau-Wong, M; Chen, SS; Seeman, P; Staiman, A1
Allikmets, L; Delgado, JM1
Allikmets, L; Delgado, JM; Richards, SA1
Baden, MM; Valanju, NN; Valanju, SN; Verma, SK1
Elliott, KA; Gottesfeld, Z1
Gorosito, M; Sabelli, HC1
Bartelheimer, HK; Bauditz, W1
Nott, MW1
Eandi, M; Ricci Gamalero, S1
Eastwood, AB; Suarez-Kurtz, G1
Bente, P; Berger, TA; Crocket, I; Farrell, W; Fogleman, K; Osonubi, M; Staats, T1
Goh, CH; Tam, KC; Tan, JP1
Akhlaghi, SP; Berry, RM; Tam, KC; Tiong, D1

Reviews

1 review(s) available for imipramine and procaine

ArticleYear
Drug interactions with cimetidine: an update.
    Pharmacology & therapeutics, 1985, Volume: 27, Issue:3

    Topics: Absorption; Acetaminophen; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Anti-Bacterial Agents; Anticoagulants; Anticonvulsants; Aspirin; Aziridines; Benzodiazepines; Benzoquinones; Cimetidine; Drug Interactions; Humans; Ibuprofen; Imipramine; Kinetics; Lidocaine; Liver Circulation; Pituitary Gland; Procaine; Xanthines

1985

Trials

1 trial(s) available for imipramine and procaine

ArticleYear
Treatment of depression in the aged with gerovital H3: clinical efficacy and neurophysiological effects.
    Psychopharmacology bulletin, 1976, Volume: 12, Issue:2

    Topics: Aged; Clinical Trials as Topic; Depression; Humans; Imipramine; Middle Aged; Placebos; Procaine; Psychiatric Status Rating Scales

1976

Other Studies

34 other study(ies) available for imipramine and procaine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design.
    Journal of medicinal chemistry, 2020, 02-27, Volume: 63, Issue:4

    Topics: Binding Sites; Chemistry, Pharmaceutical; Drug Design; Humans; Hydrogen-Ion Concentration; Molecular Docking Simulation; Pharmaceutical Preparations; Protein Binding; Serum Albumin, Human; Spectrophotometry, Ultraviolet; Titrimetry

2020
Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds.
    Journal of medicinal chemistry, 2021, 04-22, Volume: 64, Issue:8

    Topics: Binding Sites; Crystallography, X-Ray; Drug Stability; Humans; Kelch-Like ECH-Associated Protein 1; Ligands; Magnetic Resonance Spectroscopy; Microsomes; Molecular Dynamics Simulation; NF-E2-Related Factor 2; Protein Binding; Protein Interaction Maps; Small Molecule Libraries; Structure-Activity Relationship; Surface Plasmon Resonance

2021
Skeletal muscle necrosis following membrane-active drugs plus serotonin.
    Journal of the neurological sciences, 1976, Volume: 28, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Disease Models, Animal; Drug Synergism; Histamine H1 Antagonists; Imipramine; Male; Muscular Dystrophies; Procaine; Rats; Serotonin; Trihexyphenidyl

1976
Enhanced synthesis de novo of phosphatidylinositol in lymphocytes treated with cationic amphiphilic drugs.
    The Biochemical journal, 1975, Volume: 148, Issue:3

    Topics: Amphetamine; Animals; Cetrimonium Compounds; Chlorpromazine; Cocaine; Dibucaine; Dose-Response Relationship, Drug; Fenfluramine; Imipramine; Lectins; Lymphocytes; Phenethylamines; Phosphatidylinositols; Procaine; Promethazine; Swine; Time Factors; Trifluoperazine

1975
Serotonin accumulation by skeletal muscle.
    Experimental neurology, 1977, Volume: 54, Issue:1

    Topics: Animals; Biological Transport; Chlorpheniramine; Chlorpromazine; Clomipramine; Dose-Response Relationship, Drug; Imipramine; Iprindole; Male; Muscles; Muscular Dystrophies; Procaine; Rats; Serotonin; Temperature; Urea

1977
Pituitary thyrotropin-releasing hormone receptors: local anesthetic effects on binding and responses.
    Molecular endocrinology (Baltimore, Md.), 1989, Volume: 3, Issue:9

    Topics: Anesthetics, Local; Animals; Benzocaine; Chlordiazepoxide; Chlorpromazine; Dibucaine; Hydrogen-Ion Concentration; Imipramine; Lidocaine; Pituitary Gland; Procaine; Prolactin; Propranolol; Rats; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Tetracaine; Thyrotropin-Releasing Hormone; Trifluoperazine; Verapamil

1989
A study of the mechanism by which some amphiphilic drugs affect human erythrocyte acetylcholinesterase activity.
    The Biochemical journal, 1989, Jul-15, Volume: 261, Issue:2

    Topics: Acetylcholinesterase; Anesthetics, Local; Cholinesterase Inhibitors; Erythrocyte Membrane; Erythrocytes; Humans; Imipramine; Kinetics; Lidocaine; Membrane Fluidity; Procaine; Tetracaine

1989
The discriminative stimulus properties of mepyramine.
    Life sciences, 1985, Sep-23, Volume: 37, Issue:12

    Topics: Aminopyridines; Animals; Chlorpheniramine; Discrimination, Psychological; Histamine H1 Antagonists; Imipramine; Male; Procaine; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Scopolamine

1985
[Effect of psychotropic drugs on the K + -dependent phosphatase activity in guinea pig brain microsomes].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Chlordiazepoxide; Chlorpromazine; Desipramine; Diazepam; Guinea Pigs; Histamine; Hydroxyzine; Imipramine; Meprobamate; Microsomes; Morphine; Nialamide; Phenelzine; Phenobarbital; Phenoxybenzamine; Phosphoric Monoester Hydrolases; Pilocarpine; Potassium; Procaine; Reserpine; Tranquilizing Agents

1972
Effects of desipramine and imipramine on the nerve, muscle and synaptic transmission of rat diaphragms.
    Neuropharmacology, 1972, Volume: 11, Issue:6

    Topics: Acetylcholine; Action Potentials; Animals; Axons; Chlorpromazine; Desipramine; Diaphragm; Electric Stimulation; Imipramine; In Vitro Techniques; Membrane Potentials; Microelectrodes; Muscle Contraction; Neuromuscular Junction; Neurons; Phrenic Nerve; Procaine; Rats; Stimulation, Chemical; Synaptic Transmission

1972
[Electrophysiological analysis of the effects of imipramine on heart ventricle fibre].
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 181, Issue:1

    Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Bicarbonates; Calcium Chloride; Cell Membrane Permeability; Electrodes; Guinea Pigs; Heart; Heart Ventricles; Imipramine; Lactates; Membrane Potentials; Potassium Chloride; Procaine; Quinidine; Rats; Sodium; Tetrodotoxin; Time Factors

1969
Brain uptake of metabolites and drugs following carotid arterial injections.
    Transactions of the American Neurological Association, 1971, Volume: 96

    Topics: Acetates; Amino Acids; Animals; Antipyrine; Ascorbic Acid; Aspirin; Barbiturates; Blood-Brain Barrier; Brain; Caffeine; Chloroquine; Cyanides; Ethanol; Imipramine; Lactates; Mescaline; Morphine; Neurotransmitter Agents; Nicotine; Penicillin G; Pharmaceutical Preparations; Phenytoin; Procaine; Pyruvates; Rats

1971
Calcium reversal of nerve blockade by alcohols, anesthetics, tranquilizers, and barbiturates.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:3

    Topics: Action Potentials; Alcohols; Anesthetics; Animals; Barbiturates; Benzyl Compounds; Buffers; Calcium; Carbon Radioisotopes; Chlorpromazine; Imipramine; In Vitro Techniques; Lidocaine; Membranes; Nerve Block; Neural Conduction; Pentobarbital; Phrenic Nerve; Procaine; Promethazine; Rats; Sulfur Radioisotopes; Tetrodotoxin; Thymol; Time Factors; Tranquilizing Agents

1974
Injection of antidepressants in the amygdala of awake monkeys.
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 175, Issue:1

    Topics: Amitriptyline; Amygdala; Animals; Antidepressive Agents; Chlorprothixene; Electric Stimulation; Electroencephalography; Haplorhini; Imipramine; Injections; Procaine; Promazine

1968
Intra-mesencephalic injection of imipramine, promazine and chlorprothixene in awake monkeys.
    International journal of neuropharmacology, 1968, Volume: 7, Issue:3

    Topics: Animals; Attention; Chlorprothixene; Electric Stimulation; Haplorhini; Imipramine; Injections; Mesencephalon; Motor Activity; Procaine; Promazine; Social Behavior; Tectum Mesencephali

1968
Confirmed identification of biotransformed drugs of abuse in urine.
    American journal of clinical pathology, 1972, Volume: 57, Issue:1

    Topics: Amphetamine; Analgesics; Barbiturates; Biotransformation; Caffeine; Cannabis; Chromatography, Gas; Chromatography, Thin Layer; Codeine; Humans; Hydrogen-Ion Concentration; Imipramine; Indicators and Reagents; Methadone; Morphine; Nicotine; Pharmaceutical Preparations; Procaine; Skin; Spectrum Analysis; Substance-Related Disorders; Tranquilizing Agents

1972
Factors that affect the binding and uptake of gaba by brain tissue.
    Journal of neurochemistry, 1971, Volume: 18, Issue:5

    Topics: Acetylcholine; Aminobutyrates; Animals; Brain; Bromides; Cerebral Cortex; Cevanes; Chloral Hydrate; Chlorides; Chlorpromazine; Dopamine; Glutamates; Imipramine; Iodides; Lidocaine; Neostigmine; Norepinephrine; Ouabain; Phosphates; Picrotoxin; Procaine; Rats; Sodium Chloride; Tetrodotoxin

1971
Evidence for biogenic amine receptors in toad sciatic nerves.
    International journal of neuropharmacology, 1969, Volume: 8, Issue:6

    Topics: Animals; Anura; Axons; Chlorpromazine; Chlorzoxazone; Cocaine; Drug Antagonism; Epinephrine; Histamine; Imipramine; Lysergic Acid Diethylamide; Membranes; Neural Conduction; Nicotine; Nicotinic Acids; Pentolinium Tartrate; Potassium Chloride; Procaine; Sciatic Nerve; Sensory Receptor Cells; Serotonin; Sodium; Time Factors

1969
[Treatment of imipramine poisoning at childhood].
    Monatsschrift fur Kinderheilkunde, 1970, Volume: 118, Issue:11

    Topics: Arrhythmias, Cardiac; Carbon; Child, Preschool; Chloral Hydrate; Coma; Gastric Lavage; Humans; Hypotension; Imipramine; Magnesium Sulfate; Male; Norepinephrine; Oxygen Inhalation Therapy; Paraldehyde; Procaine; Propranolol; Renal Dialysis; Respiration, Artificial; Respiratory Insufficiency; Seizures

1970
Potentiation of morphine analgesia by cocaine in mice.
    European journal of pharmacology, 1968, Volume: 5, Issue:1

    Topics: Amphetamine; Analgesia; Animals; Cocaine; Dibucaine; Drug Synergism; Female; Imipramine; Lidocaine; Male; Mice; Morphine; Norepinephrine; Phentolamine; Procaine; Rats; Reserpine

1968
[Evaluation in vitro of the local anesthetic effect by means of the dose/stabilization effect curve].
    Bollettino della Societa italiana di biologia sperimentale, 1980, Jan-15, Volume: 56, Issue:1

    Topics: Anesthetics, Local; Animals; Dose-Response Relationship, Drug; Imipramine; In Vitro Techniques; Lidocaine; Nerve Block; Procaine; Promazine; Rana pipiens; Sciatic Nerve

1980
Release of creatine kinase and lactate dehydrogenase from frog skeletal muscles treated with imipramine.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 221, Issue:2

    Topics: Animals; Anura; Chlorides; Creatine Kinase; Hypertonic Solutions; Imipramine; In Vitro Techniques; L-Lactate Dehydrogenase; Lidocaine; Muscles; Procaine; Rana pipiens

1982
The development of a semi-preparatory scale supercritical-fluid chromatograph for high-throughput purification of 'combi-chem' libraries.
    Journal of biochemical and biophysical methods, 2000, Jul-05, Volume: 43, Issue:1-3

    Topics: 4-Aminobenzoic Acid; Antipyrine; Benzamides; Butylamines; Carbon Dioxide; Chromatography; Combinatorial Chemistry Techniques; Imipramine; Methanol; para-Aminobenzoates; Peptide Library; Procaine; Propylamines; Time Factors

2000
Comparative drug release studies of two cationic drugs from pH-responsive nanogels.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2007, Volume: 32, Issue:4-5

    Topics: Acrylates; Calorimetry; Cations; Drug Delivery Systems; Electrodes; Hydrogen Bonding; Hydrogen-Ion Concentration; Imipramine; Methacrylates; Molecular Structure; Nanogels; Phthalic Acids; Polyethylene Glycols; Polyethyleneimine; Polymers; Procaine; Solubility; Time Factors

2007
Comparative release studies of two cationic model drugs from different cellulose nanocrystal derivatives.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2014, Volume: 88, Issue:1

    Topics: Calibration; Calorimetry; Cations; Cellulose; Drug Carriers; Drug Delivery Systems; Electrodes; Hot Temperature; Hydrogen-Ion Concentration; Imipramine; Nanoparticles; Nanotechnology; Oligosaccharides; Polymers; Procaine; Protein Binding; Static Electricity

2014