imipramine has been researched along with probenecid in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (42.86) | 18.7374 |
| 1990's | 1 (3.57) | 18.2507 |
| 2000's | 8 (28.57) | 29.6817 |
| 2010's | 7 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Cramer, H; Goodwin, FK; Post, RM | 1 |
| Korf, J; Meisch, JJ; van Wijk, M | 1 |
| Brown, GL; Jimerson, DC; Post, RM; Smith, CC; Tallman, JF; van Kammen, DP | 1 |
| Argenta, G; Casati, C; Dolfini, E; Jori, A | 1 |
| Frazer, A; Mendels, J | 1 |
| Goodwin, FK; Post, RM | 3 |
| Miyamoto, JK; Terashima, S; Uezu, E; Yusa, T | 1 |
| Korf, J; van Praag, HM | 1 |
| Chase, TN | 1 |
| Bruinvels, J | 1 |
| Sharman, DF | 1 |
4 review(s) available for imipramine and probenecid
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Serotonergic mechanisms and extrapyramidal function in man.
Topics: 5-Hydroxytryptophan; Carbidopa; Cerebellar Diseases; Creutzfeldt-Jakob Syndrome; Down Syndrome; Extrapyramidal Tracts; Fenclonine; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Imipramine; Levodopa; Muscular Diseases; Paralysis; Parkinson Disease; Parkinson Disease, Secondary; Probenecid; Reserpine; Serotonin; Spinal Cord Diseases; Tetrabenazine; Time Factors | 1974 |
1 trial(s) available for imipramine and probenecid
| Article | Year |
|---|---|
Effect of ECT and imipramine treatment on the concentration of 5-hydroxyindoleacetic acid (5HIAA) and homovanillic acid (HVA) in the cerebrospinal fluid of depressed patients.
Topics: Adult; Clinical Trials as Topic; Depression; Electroconvulsive Therapy; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Imipramine; Male; Middle Aged; Phenylacetates; Probenecid | 1975 |
23 other study(ies) available for imipramine and probenecid
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Cyclic AMP in cerebrospinal fluid of manic and depressive patients.
Topics: Administration, Oral; Amitriptyline; Bipolar Disorder; Cyclic AMP; Depression; Humans; Imipramine; Lithium; Methadone; Methyltyrosines; Physical Exertion; Probenecid; Tryptophan | 1977 |
Metabolism of 5-hydroxytryptamine and levels of tricyclic antidepressant drugs in rat brain after acute and chronic treatment.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Desipramine; Drug Administration Schedule; Imipramine; Male; Probenecid; Protriptyline; Rats; Serotonin | 1977 |
An examination of baseline and drug-induced levels of cyclic nucleotides in the cerebrospinal fluid of control and psychiatric patients.
Topics: Adolescent; Adult; Aged; Amitriptyline; Bipolar Disorder; Depression; Humans; Imipramine; Lithium; Middle Aged; Nucleotides, Cyclic; Pimozide; Piribedil; Probenecid; Schizophrenia | 1976 |
Reduced central serotonergic activity in mania: implications for the relationship between depression and mania.
Topics: Bipolar Disorder; Brain; Depression; Disease Models, Animal; Humans; Hydroxyindoleacetic Acid; Hypnotics and Sedatives; Imipramine; Lithium; Methysergide; Monoamine Oxidase Inhibitors; Phenylalanine; Probenecid; Serotonin; Tryptophan | 1975 |
Cerebrospinal fluid amine metabolites in affective illness and schizophrenia: clinical and pharmacological studies.
Topics: Affective Symptoms; Amines; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Imipramine; Probenecid; Schizophrenia | 1975 |
Efflux of 5-HIAA from 5-HT neurons: a membrane potential-dependent process.
Topics: Animals; Brain; Brain Mapping; Cats; Hydroxyindoleacetic Acid; Imipramine; Membrane Potentials; Potassium Channels; Probenecid; Receptors, Serotonin; Serotonin; Synaptic Membranes; Synaptic Transmission | 1990 |
Action of p-chloroamphetamine on cerebral serotonin metabolism: an hypothesis.
Topics: Adrenergic Agents; Amphetamine; Animals; Brain; Chlorine; Depression, Chemical; Hydroxyindoleacetic Acid; Imipramine; Male; Mice; Probenecid; Serotonin | 1972 |
Brain serotonin, affective illness, and antidepressant drugs: cerebrospinal fluid studies with probenecid.
Topics: Affective Symptoms; Amitriptyline; Antidepressive Agents; Brain; Brain Chemistry; Depression; Fenclonine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Imipramine; Probenecid; Serotonin; Spinal Puncture; Time Factors; Tryptophan | 1974 |
Inhibition of the biosynthesis of 5-hydroxytryptamine in rat brain by imipramine.
Topics: Animals; Brain; Brain Chemistry; Carbon Isotopes; Fluorometry; Hydroxyindoleacetic Acid; Imipramine; Kinetics; Male; Probenecid; Rats; Serotonin; Serotonin Antagonists; Spectrometry, Fluorescence; Synaptosomes; Time Factors; Tryptophan | 1972 |
Changes in the metabolism of 3,4-dihydroxyphenylethylamine (dopamine) in the striatum of the mouse induced by drugs.
Topics: Anesthetics; Animals; Behavior, Animal; Brain; Dopamine; Drug Antagonism; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Methylphenidate; Methyltyrosines; Mice; Mixed Function Oxygenases; Monoamine Oxidase; Morphine; Parasympatholytics; Parasympathomimetics; Pargyline; Phencyclidine; Phenylacetates; Pilocarpine; Probenecid; Reserpine; Tolazoline; Tranquilizing Agents; Tyrosine; Zoxazolamine | 1966 |
5-hydroxytryptamine and depression: a model for the interaction of normal variance with pathology.
Topics: Aggression; Animals; Autopsy; Biogenic Amines; Depressive Disorder; Humans; Hydroxyindoleacetic Acid; Imipramine; Models, Biological; Mood Disorders; Probenecid; Serotonin; Suicide | 1983 |