imipramine and pindolol

imipramine has been researched along with pindolol in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19905 (15.63)18.7374
1990's5 (15.63)18.2507
2000's12 (37.50)29.6817
2010's10 (31.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Caron, G; Ermondi, G1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Abraham, MH; Acree, WE; Ibrahim, A1
Lombardo, F; Obach, RS; Waters, NJ1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Campillo, NE; Guerra, A; Páez, JA1
Gozalbes, R; Pineda-Lucena, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Akamatsu, M1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Baba, S; Horisawa, T; Kato, T; Kinomura, N; Kodo, T; Koyama, K; Masumoto, S; Matsumoto, K; Matsumoto, Y; Oki, H; Yabuuchi, K; Yoshinaga, H1
Artymyshyn, R; Bird, ED; Cassanova, MF; Joyce, JN; Kim, SJ; Kleinman, JE; Lawrence, D; Lexow, N; Senzon, S; Winokur, A1
Ishikawa, K; Kameyama, T; Nabeshima, T; Yamaguchi, K; Yoshida, S1
Breese, GR; Duncan, GE; Fassberg, JB; Paul, IA; Powell, KR; Stumpf, WE1
Cooke, R; Ellis, PM; McIntosh, CJ; Stowell, LI1
Chiu, A; Li, PP; Sibony, D; Warsh, JJ1
Lange, F; Lange, J; Morin, D; Tillement, JP; Zini, R1
McNaughton, N; Zhu, XO1
Hietala, J; Kuoppamäki, M; Laakso, A; Pälvimäki, EP; Syvälahti, E1
Breese, GR; Duncan, GE; Knapp, DJ; Little, KY1
Berrino, L; Leyva, J; Maione, S; Palazzo, E; Pallotta, M; Rossi, F1

Reviews

1 review(s) available for imipramine and pindolol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

31 other study(ies) available for imipramine and pindolol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Discovery of SMP-304, a novel benzylpiperidine derivative with serotonin transporter inhibitory activity and 5-HT
    Bioorganic & medicinal chemistry, 2017, 01-01, Volume: 25, Issue:1

    Topics: Animals; Antidepressive Agents; Cytochrome P-450 CYP2D6 Inhibitors; Dioxanes; Drug Partial Agonism; Humans; Male; Piperidines; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Serotonin Plasma Membrane Transport Proteins

2017
Distribution of beta-adrenergic receptor subtypes in human post-mortem brain: alterations in limbic regions of schizophrenics.
    Synapse (New York, N.Y.), 1992, Volume: 10, Issue:3

    Topics: Adult; Autopsy; Autoradiography; Brain; Cell Membrane; Female; Humans; Imipramine; Iodine Radioisotopes; Limbic System; Male; Middle Aged; N-Methylscopolamine; Organ Specificity; Pindolol; Pirenzepine; Receptors, Adrenergic, beta; Schizophrenia; Scopolamine Derivatives; Serotonin Antagonists; Suicide; Tritium

1992
Phencyclidine-induced head-weaving and head-twitch through interaction with 5-HT1 and 5-HT2 receptors in reserpinized rats.
    Neuropharmacology, 1987, Volume: 26, Issue:10

    Topics: Animals; Brain; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Male; Methoxydimethyltryptamines; p-Chloroamphetamine; Phencyclidine; Pindolol; Piperidines; Rats; Rats, Inbred F344; Receptors, Serotonin; Reserpine; Ritanserin; Serotonin; Serotonin Antagonists; Stereotyped Behavior

1987
Neuroanatomically selective down-regulation of beta adrenergic receptors by chronic imipramine treatment: relationships to the topography of [3H]imipramine and [3H] desipramine binding sites.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:1

    Topics: Animals; Autoradiography; Brain Chemistry; Carrier Proteins; Imipramine; Male; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Drug; Receptors, Neurotransmitter

1989
Adrenoceptor and imipramine receptor binding during the menstrual cycle.
    Acta psychiatrica Scandinavica, 1988, Volume: 78, Issue:3

    Topics: Adult; Blood Platelets; Carrier Proteins; Dihydroergotoxine; Female; Humans; Imipramine; Lymphocytes; Menstrual Cycle; Pindolol; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Drug; Receptors, Neurotransmitter

1988
Assessment of rat brain alpha 1-adrenoceptor binding and activation of inositol phospholipid turnover following chronic imipramine treatment.
    Neurochemical research, 1988, Volume: 13, Issue:12

    Topics: Animals; Cerebral Cortex; Desipramine; Imipramine; In Vitro Techniques; Inositol Phosphates; Iodocyanopindolol; Norepinephrine; Pindolol; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic, alpha; Sugar Phosphates

1988
Alterations of beta-adrenergic, muscarinic cholinergic receptors and imipramine binding sites in human lung tumors.
    International journal of clinical pharmacology, therapy, and toxicology, 1987, Volume: 25, Issue:11

    Topics: Adenocarcinoma; Adrenergic beta-Antagonists; Carcinoma, Squamous Cell; Humans; Imipramine; In Vitro Techniques; Lung Neoplasms; Pindolol; Quinuclidinyl Benzilate; Receptors, Adrenergic, beta; Receptors, Cholinergic; Receptors, Muscarinic

1987
The interaction of serotonin depletion with anxiolytics and antidepressants on reticular-elicited hippocampal RSA.
    Neuropharmacology, 1994, Volume: 33, Issue:12

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Buspirone; Cytidine Diphosphate; Drug Interactions; Electric Stimulation; Electroencephalography; Hippocampus; Imipramine; Male; Pindolol; Rats; Rats, Sprague-Dawley; Reticular Formation; Serotonin; Theta Rhythm

1994
Up-regulation of beta 1-adrenergic receptors in rat brain after chronic citalopram and fluoxetine treatments.
    Psychopharmacology, 1994, Volume: 115, Issue:4

    Topics: Adrenergic beta-1 Receptor Agonists; Animals; Autoradiography; Brain Chemistry; Citalopram; Fluoxetine; Image Processing, Computer-Assisted; Imipramine; Iodocyanopindolol; Male; Pindolol; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Up-Regulation

1994
Neuroanatomical specificity and dose dependence in the time course of imipramine-induced beta adrenergic receptor down-regulation in rat brain.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:3

    Topics: Animals; Brain Chemistry; Dose-Response Relationship, Drug; Down-Regulation; Imipramine; Male; Pindolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta

1994
Effects of imipramine on raphe nuclei and prefrontal cortex extracellular serotonin levels in the rat.
    Psychopharmacology, 1997, Volume: 134, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Antidepressive Agents, Tricyclic; Extracellular Space; Imipramine; Male; Microdialysis; Pindolol; Prefrontal Cortex; Raphe Nuclei; Rats; Rats, Wistar; Serotonin

1997