imipramine and pimozide

imipramine has been researched along with pimozide in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19907 (25.93)18.7374
1990's2 (7.41)18.2507
2000's12 (44.44)29.6817
2010's6 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Butler, DE; Marriott, JG; Poschel, BP1
Topliss, JG; Yoshida, F1
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M1
Keserü, GM1
Li, J; Rajamani, R; Reynolds, CH; Tounge, BA1
Nagashima, R; Nishikawa, T; Tobita, M1
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Jia, L; Sun, H1
Caron, G; Ermondi, G; Visentin, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Sen, S; Sinha, N1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Francès, H; Puech, AJ; Simon, P1
Brown, GL; Jimerson, DC; Post, RM; Smith, CC; Tallman, JF; van Kammen, DP1
Klimek, V; Maj, J; Rawlów, A; Sarnek, J1
Muscat, R; Sampson, D; Willner, P1
Fujita, M; Horikomi, K1
Maj, J; Smiałowski, A1
Castro, JA; de Fenos, OM; de Ferreyra, EC1
Blakely, RD; Jansen, K; Richelson, E; Tatsumi, M1
Erdinc, E; Esel, E; Gonul, AS; Karaaslan, F; Oguz, A1
Ghaffari-Nejad, A; Toofani, K1
Kenchaiah, BK; Kumar, S; Tharyan, P1

Reviews

1 review(s) available for imipramine and pimozide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

26 other study(ies) available for imipramine and pimozide

ArticleYear
Cognition-activating properties of 3-(Aryloxy)pyridines.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Animals; Cognition; Dose-Response Relationship, Drug; Male; Mice; Psychotropic Drugs; Pyridines; Structure-Activity Relationship

1981
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
    Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18

    Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2002
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
A two-state homology model of the hERG K+ channel: application to ligand binding.
    Bioorganic & medicinal chemistry letters, 2005, Mar-15, Volume: 15, Issue:6

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation

2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
    Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18

    Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride

2005
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:5

    Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
    Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection

2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Imipramine antagonism of apomorphine-induced hypothermia: a non-dopaminergic interaction.
    European journal of pharmacology, 1978, Jan-01, Volume: 47, Issue:1

    Topics: Animals; Apomorphine; Body Temperature; Dopamine; Imipramine; Male; Mice; Pimozide; Sulpiride

1978
An examination of baseline and drug-induced levels of cyclic nucleotides in the cerebrospinal fluid of control and psychiatric patients.
    Life sciences, 1976, Jul-01, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Amitriptyline; Bipolar Disorder; Depression; Humans; Imipramine; Lithium; Middle Aged; Nucleotides, Cyclic; Pimozide; Piribedil; Probenecid; Schizophrenia

1976
On the anticataleptic action of cyproheptadine.
    Pharmacology, biochemistry, and behavior, 1976, Volume: 5, Issue:2

    Topics: Animals; Atropine; Catalepsy; Clomipramine; Cyproheptadine; Desipramine; Female; Fluphenazine; Humans; Imipramine; Male; Methyltyrosines; Pilocarpine; Pimozide; Promethazine; Rats; Reserpine; Spiperone

1976
Dopaminergic mechanism of imipramine action in an animal model of depression.
    Biological psychiatry, 1990, Aug-01, Volume: 28, Issue:3

    Topics: Animals; Appetitive Behavior; Arousal; Depressive Disorder; Drinking; Imipramine; Male; Metergoline; Pimozide; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Salicylamides; Taste

1990
[Comparative study of the pharmacological properties of sultopride sulpiride and other antipsychotic drugs: influence of sultopride, sulpiride and other antipsychotic drugs on spontaneous locomotor activity and changes in locomotor activity induced by apo
    Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1986, Volume: 6, Issue:3

    Topics: Amisulpride; Animals; Antipsychotic Agents; Apomorphine; Chlorpromazine; Clonidine; Drug Interactions; Haloperidol; Imipramine; Male; Mice; Motor Activity; Pimozide; Sulpiride; Yohimbine

1986
Repeated treatment with imipramine potentiates the locomotor effect of apomorphine administered into the hippocampus in rats.
    Psychopharmacology, 1985, Volume: 86, Issue:4

    Topics: Animals; Apomorphine; Dose-Response Relationship, Drug; Drug Synergism; Hippocampus; Imipramine; Male; Motor Activity; Pimozide; Rats; Rats, Inbred Strains; Receptors, Dopamine

1985
Late preventive effects of several anticalmodulin drugs on galactosamine-induced liver necrosis.
    Research communications in chemical pathology and pharmacology, 1985, Volume: 47, Issue:2

    Topics: Animals; Calmodulin; Galactosamine; Imipramine; Liver; Male; Necrosis; Pimozide; Rats; Thioridazine; Trifluoperazine

1985
Pharmacological profile of neuroleptics at human monoamine transporters.
    European journal of pharmacology, 1999, Mar-05, Volume: 368, Issue:2-3

    Topics: Antipsychotic Agents; Carrier Proteins; Cell Line; Chlorpromazine; Cocaine; Dibenzazepines; Dibenzothiepins; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Humans; Imipramine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Pimozide; Piperazines; Protein Binding; Radioligand Assay; Recombinant Fusion Proteins; Serotonin Plasma Membrane Transport Proteins; Symporters; Thiazoles; Triflupromazine; Tritium

1999
P300 changes in major depressive disorders with and without psychotic features.
    Journal of affective disorders, 2003, Volume: 73, Issue:3

    Topics: Adult; Affective Disorders, Psychotic; Antidepressive Agents; Antipsychotic Agents; Cerebral Cortex; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Drug Therapy, Combination; Electroencephalography; Event-Related Potentials, P300; Female; Follow-Up Studies; Humans; Imipramine; Male; Middle Aged; Personality Inventory; Pimozide; Reaction Time; Reference Values; Selective Serotonin Reuptake Inhibitors

2003
Delusion of oral parasitosis in a patient with major depressive disorder.
    Archives of Iranian medicine, 2006, Volume: 9, Issue:1

    Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Delusions; Depressive Disorder, Major; Female; Humans; Imipramine; Mouth; Parasitic Diseases; Pimozide

2006
Atypical anti-psychotics in delusional parasitosis: a retrospective case series of 20 patients.
    International journal of dermatology, 2010, Volume: 49, Issue:1

    Topics: Antipsychotic Agents; Benzodiazepines; Ectoparasitic Infestations; Female; Fluoxetine; Haloperidol; Humans; Imipramine; Male; Middle Aged; Olanzapine; Pimozide; Retrospective Studies; Risperidone; Schizophrenia, Paranoid; Sertraline

2010