imipramine and phenytoin

imipramine has been researched along with phenytoin in 89 studies

Research

Studies (89)

Timeframe	Studies, this research(%)	All Research%
pre-1990	60 (67.42)	18.7374
1990's	3 (3.37)	18.2507
2000's	11 (12.36)	29.6817
2010's	15 (16.85)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Beard, CC; Dvorak, C; Marx, M; Patterson, J; Roszkowski, A; Schuler, M; Unger, SH; Wagner, PJ; Wallach, MB; Weinhardt, K	1
Duffy, EM; Jorgensen, WL	1
Topliss, JG; Yoshida, F	1
Faller, B; Wohnsland, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Caron, G; Ermondi, G	1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R	1
Abraham, MH; Acree, WE; Ibrahim, A	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Gozalbes, R; Pineda-Lucena, A	1
Akamatsu, M	1
Sen, S; Sinha, N	1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bissada, NK; Finkbeiner, AE; Welch, LT	1
Elvidge, JA; Jones, JR; Saljoughian, M	1
Buchanan, N	1
d'Athis, P; Lecomte, M; Tillement, JP; Zini, R	1
Kaneyuki, T; Kohsaka, M; Shohmori, T	2
Davis, CM; Fenimore, DC; Meyer, CJ	1
Perucca, E; Richens, A	1
Bellak, L	1
Beaubien, AR; Carpenter, DC; Hrdina, PD; MacConaill, M; Mathieu, LF	1
Danielson, MG; Fowler, GW; Julien, RM	1
Beaubien, AR; Carpenter, DC; Hrdina, PD; Mathieu, LF	1
Gigon, PL	2
Zbinden, G	1
McIlwain, H; Pull, I	1
Kitteringham, NR; Park, BK; Riley, RJ; Roberts, P	1
Martinez, C; Montini, C; Oliva, J; Ramirez, H	1
Roden, DM; Siddoway, LA; Woosley, RL	1
Dailey, JW; Jobe, PC	1
Abernethy, DR; Greenblatt, DJ; Morse, DS	1
Andrews, PR; Lloyd, EJ	1
Goode, DJ; Meltzer, HY	1
Greengard, P; Quinn, GP; Reid, MB	1
Barron, DI; Hall, GH; Natoff, IL; Vallance, DK	1
Brittain, RT	1
Baxter, BL	1
Oldendorf, WH	1
Kamei, C; Shimomura, K; Ueki, S	1
Grinberg, KN; Shapiro, IuL; Vaĭntrub, MIa; Zhurkov, VS	1
Kanarek, KS; Levin, SE; Thomson, PD	1
Postlethwaite, RJ; Price, DA	1
Remmer, H	1
Greenberg, IM; Klein, DF	1
Casaccia, M; Halter, J; Lichtlen, P; Moccetti, T; Mohr, P	1
Trautmann, A	1
Baum, T; Eckfeld, DK; Rowles, G; Shropshire, AT; Varner, LL	1
Dayton, PG; Pruitt, AW	1
Bhalla, TN; Bhargava, KP; Kohli, RP; Sinha, JN	1
Azarnoff, DL; Borgå, O; Forshell, GP; Sjöqvist, F	1
Hata, T; Kita, T; Murakami, T	1
Coeugniet, E; Dobrescu, D	1
Calhoun, FJ; Schrogie, JJ; Tolson, WW	1
Nissen, G	1
Daughaday, WH; Kipnis, DM; Takahashi, Y	1
Jenny, E; Solberg, R	1
Baldwin, RL; Peters, JE	1
Olesen, OV	1
Fromm, GH; Killian, JM	1
Snyder, S	1
Horiuchi, M; Ibii, N; Yamamoto, K	1
Conner, CS	1
Müller-Oerlinghausen, B; Schley, J	1
Greer, NL; Schechter, MD	1
Olczak, S	1
Bittar, EE; Nwoga, J	1
Campbell, M; Cueva, JE	1
Anraku, T; Iwashita, Y; Nakamura, J; Nakazawa, Y; Shirouzu, M	1

Reviews

7 review(s) available for imipramine and phenytoin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Uropharmacology: X. Central nervous system stimulants and depressants. Urology, 1979, Volume: 13, Issue:4 Topics: Amphetamines; Anesthetics; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Baclofen; Benzodiazepines; Central Nervous System Agents; Chloral Hydrate; Humans; Imipramine; Levodopa; Meperidine; Meprobamate; Morphine; Nortriptyline; Paraldehyde; Phenothiazines; Phenytoin; Picrotoxin; Reserpine; Strychnine; Urinary Tract	1979
Protein binding of drugs--the clinical significance. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1978, Jun-03, Volume: 53, Issue:22 Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Anticoagulants; Humans; Imipramine; Kidney; Kidney Diseases; Liver; Liver Diseases; Pharmaceutical Preparations; Phenytoin; Protein Binding; Serum Albumin	1978
Clinical pharmacology of old and new antiarrhythmic drugs. Cardiovascular clinics, 1985, Volume: 15, Issue:3 Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Biological Availability; Bretylium Compounds; Disopyramide; Encainide; Flecainide; Humans; Imipramine; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Tocainide	1985
[Teratogenic and mutagenic effects of anticonvulsive and psychotropic drugs (review of the literature)]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1972, Volume: 72, Issue:6 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Antidepressive Agents; Arm; Barbiturates; Chlorpromazine; Chromosome Aberrations; Chromosome Disorders; Cricetinae; Drosophila; Female; Heart Defects, Congenital; Humans; Imipramine; Infant, Newborn; Jaundice, Neonatal; Mutagens; Perphenazine; Phenothiazines; Phenytoin; Pregnancy; Primidone; Rabbits; Thalidomide; Tranquilizing Agents; Trifluoperazine	1972
The interaction of psychopharmacology and psychoanalysis in the borderline patient. The Psychiatric quarterly, 1980,Winter, Volume: 52, Issue:4 Topics: Affect; Anger; Antipsychotic Agents; Borderline Personality Disorder; Chlorpromazine; Clinical Trials as Topic; Depression; Double-Blind Method; Ego; Female; Humans; Imipramine; Lithium; Male; Methods; Personality Disorders; Phenytoin; Procyclidine; Psychoanalytic Interpretation; Tranylcypromine; Trifluoperazine	1980
Psychopharmacology in child and adolescent psychiatry: a review of the past seven years. Part II. Journal of the American Academy of Child and Adolescent Psychiatry, 1995, Volume: 34, Issue:10 Topics: Adolescent; Alprazolam; Anticonvulsants; Antipsychotic Agents; Anxiety, Separation; Bipolar Disorder; Carbamazepine; Child; Child Behavior Disorders; Child, Preschool; Clonidine; Clozapine; Depressive Disorder; Dose-Response Relationship, Drug; Feeding and Eating Disorders; Fluoxetine; Humans; Imipramine; Lithium; Mutism; Obsessive-Compulsive Disorder; Phenobarbital; Phenytoin; Phobic Disorders; Schizophrenia; Sleep Wake Disorders; Tranquilizing Agents	1995

Trials

2 trial(s) available for imipramine and phenytoin

Article	Year
Behavioral effects of diphenylhydantoin in severe psychiatric disorders. The American journal of psychiatry, 1967, Volume: 124, Issue:6 Topics: Adolescent; Adult; Character; Child; Clinical Trials as Topic; Electroencephalography; Epilepsy; Female; Humans; Imipramine; Male; Mental Disorders; Middle Aged; Phenothiazines; Phenytoin; Schizophrenia	1967
The interaction of psychopharmacology and psychoanalysis in the borderline patient. The Psychiatric quarterly, 1980,Winter, Volume: 52, Issue:4 Topics: Affect; Anger; Antipsychotic Agents; Borderline Personality Disorder; Chlorpromazine; Clinical Trials as Topic; Depression; Double-Blind Method; Ego; Female; Humans; Imipramine; Lithium; Male; Methods; Personality Disorders; Phenytoin; Procyclidine; Psychoanalytic Interpretation; Tranylcypromine; Trifluoperazine	1980

Article

Year

Behavioral effects of diphenylhydantoin in severe psychiatric disorders.

The American journal of psychiatry, 1967, Volume: 124, Issue:6

Topics: Adolescent; Adult; Character; Child; Clinical Trials as Topic; Electroencephalography; Epilepsy; Female; Humans; Imipramine; Male; Mental Disorders; Middle Aged; Phenothiazines; Phenytoin; Schizophrenia

1967

The interaction of psychopharmacology and psychoanalysis in the borderline patient.

The Psychiatric quarterly, 1980,Winter, Volume: 52, Issue:4

Topics: Affect; Anger; Antipsychotic Agents; Borderline Personality Disorder; Chlorpromazine; Clinical Trials as Topic; Depression; Double-Blind Method; Ego; Female; Humans; Imipramine; Lithium; Male; Methods; Personality Disorders; Phenytoin; Procyclidine; Psychoanalytic Interpretation; Tranylcypromine; Trifluoperazine

1980

Other Studies

81 other study(ies) available for imipramine and phenytoin

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Synthesis and central nervous system properties of 2-[(alkoxycarbonyl)amino]-4(5)-phenyl-2-imidazolines. Journal of medicinal chemistry, 1984, Volume: 27, Issue:5 Topics: Animals; Anticonvulsants; Antidepressive Agents; Behavior, Animal; Body Temperature Regulation; Central Nervous System; Central Nervous System Agents; Imidazoles; Indicators and Reagents; Male; Mice; Mice, Inbred ICR; Motor Activity; Muscle Relaxants, Central; Myocardium; Norepinephrine; Posture; Reserpine; Structure-Activity Relationship	1984
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes. Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6 Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water	2001
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
QSAR study on permeability of hydrophobic compounds with artificial membranes. Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11 Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship	2007
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
Importance of physicochemical properties for the design of new pesticides. Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7 Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic	2011
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Glutathione; Pharmacology; Sulfur Radioisotopes	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2 Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Catalytic tritiation of drugs and analysis of the tritium distribution by 3H n.m.r. spectroscopy. The Journal of pharmacy and pharmacology, 1979, Volume: 31, Issue:8 Topics: Amphetamine; Catalysis; Dextropropoxyphene; Imipramine; Isotope Labeling; Magnetic Resonance Spectroscopy; Phenobarbital; Phenytoin; Propranolol; Tritium	1979
Phenytoin binding to human albumin. European journal of drug metabolism and pharmacokinetics, 1979, Volume: 4, Issue:1 Topics: Anilino Naphthalenesulfonates; Fatty Acids, Nonesterified; Humans; Imipramine; Palmitic Acids; Phenylbutazone; Phenytoin; Protein Binding; Serum Albumin; Warfarin	1979
Influences of central acting drugs on delta4-3-ketosteroid 5alpha-oxidoreductase activity in rat diencephalon. Folia psychiatrica et neurologica japonica, 1977, Volume: 31, Issue:4 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Chlorpromazine; Chromatography, Thin Layer; Diencephalon; Imipramine; Male; Oxidoreductases; Phenytoin; Rats	1977
Determination of drugs in plasma by high-performance thin-layer chromatography. Clinical chemistry, 1978, Volume: 24, Issue:8 Topics: Amitriptyline; Chlorpromazine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Desipramine; Humans; Imipramine; Nortriptyline; Phenobarbital; Phenytoin; Psychotropic Drugs; Spectrophotometry, Ultraviolet	1978
Methylphenidate (ritalin) and other drugs for treatment of hyperactive children. The Medical letter on drugs and therapeutics, 1977, Jul-01, Volume: 19, Issue:13 Topics: Child; Deanol; Dextroamphetamine; Drug Interactions; Humans; Hyperkinesis; Imipramine; Methylphenidate; Pemoline; Phenytoin	1977
Interaction between phenytoin and imipramine. British journal of clinical pharmacology, 1977, Volume: 4, Issue:4 Topics: Adult; Depression; Drug Interactions; Epilepsy; Humans; Imipramine; Phenytoin; Time Factors	1977
A possible subgroup of the schizophrenic syndrome and implications for treatment. American journal of psychotherapy, 1976, Volume: 30, Issue:2 Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Diazepam; Dominance, Cerebral; Dyslexia; Female; Haloperidol; Humans; Imipramine; Impulsive Behavior; Learning Disabilities; Male; Methylphenidate; Middle Aged; Phenytoin; Psychoanalytic Therapy; Schizophrenia; Self Concept; Space Perception	1976
Antagonism of imipramine poisoning by anticonvulsants in the rat. Toxicology and applied pharmacology, 1976, Volume: 38, Issue:1 Topics: Animals; Anticonvulsants; Diazepam; Imipramine; Lethal Dose 50; Male; Phenobarbital; Phenytoin; Rats	1976
The metabolism of testosterone in the brain: the occurrence of delta4-3-ketosteroid 5 alpha-oxidoreductase and 3alpha-hydroxysteroid dehydrogenase and the effects of central acting drugs on these enzyme activities. Nihon Naibunpi Gakkai zasshi, 1976, Nov-20, Volume: 52, Issue:11 Topics: 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Brain; Chlorpromazine; Diencephalon; Imipramine; Male; Microsomes; Oxidoreductases; Phenytoin; Progesterone; Rats	1976
The effects of antiepileptic drugs on estrogen-induced electrographic spike-wave discharge. The Journal of pharmacology and experimental therapeutics, 1975, Volume: 193, Issue:2 Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Clonazepam; Clorazepate Dipotassium; Diazepam; Electroencephalography; Estrogens; Ethosuximide; Female; Imipramine; Lidocaine; Male; Motor Cortex; Phenytoin; Stereotaxic Techniques; Trimethadione	1975
Letter: Amitriptyline and imipramine poisoning in children. British medical journal, 1975, Mar-01, Volume: 1, Issue:5956 Topics: Amitriptyline; Animals; Antidotes; Humans; Imipramine; Phenytoin; Poisoning; Rats; Seizures	1975
Biotransformation and biliary excretion of imipramine in rats under various experimental conditions. Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 216, Issue:2 Topics: Animals; Bile; Biliary Fistula; Biotransformation; Brain; Female; Imipramine; Injections, Intraperitoneal; Liver; Lung; Male; Pentobarbital; Phenytoin; Rats; Sex Factors; Subcellular Fractions; Time Factors	1975
Effect of diphenylhydantoin on the biotransformation and biliary excretion of imipramine in rats. Xenobiotica; the fate of foreign compounds in biological systems, 1975, Volume: 5, Issue:10 Topics: Animals; Bile; Bile Ducts; Biotransformation; Cytochrome P-450 Enzyme System; Imipramine; Liver; Male; Organ Specificity; Phenytoin; Rats	1975
[Dangers of drug combinations (author's transl)]. Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1976, Mar-23, Volume: 65, Issue:11 Topics: Anticoagulants; Barbiturates; Contraceptives, Oral, Hormonal; Drug Antagonism; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Humans; Imipramine; Intestinal Absorption; Monoamine Oxidase Inhibitors; Phenobarbital; Phenytoin; Psychoses, Substance-Induced; Rifampin	1976
Centrally-acting drugs and related compounds examined for action on output of adenine derivatives from superfused tissues of the brain. Biochemical pharmacology, 1976, Feb-01, Volume: 25, Issue:3 Topics: Adenine; Adenine Nucleotides; Amobarbital; Animals; Brain; Chlorpromazine; Desipramine; Guinea Pigs; Imipramine; In Vitro Techniques; Lactates; Phenytoin; Psychotropic Drugs	1976
Formation of cytotoxic metabolites from phenytoin, imipramine, desipramine, amitriptyline and mianserin by mouse and human hepatic microsomes. Biochemical pharmacology, 1990, Jun-15, Volume: 39, Issue:12 Topics: 7-Alkoxycoumarin O-Dealkylase; Amitriptyline; Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Desipramine; Dibenzoxazepines; Enzyme Induction; Humans; Imipramine; Injections, Intraperitoneal; Male; Mianserin; Mice; Mice, Inbred CBA; Microsomes, Liver; Phenobarbital; Phenytoin	1990
[Pharmacotherapy of trigeminal neuralgia]. Odontologia chilena, 1989, Volume: 37, Issue:2 Topics: Amphetamines; Baclofen; Carbamazepine; Female; Humans; Imipramine; Male; Phenytoin; Trigeminal Neuralgia	1989
Anticonvulsant drugs and the genetically epilepsy-prone rat. Federation proceedings, 1985, Volume: 44, Issue:10 Topics: Acoustic Stimulation; Amitriptyline; Animals; Anticonvulsants; Carbamazepine; Desipramine; Disease Models, Animal; Epilepsy; Ethosuximide; Imipramine; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Valproic Acid	1985
Methodologic factors influencing plasma binding of alpha-1-acid glycoprotein-bound and albumin-bound drugs. International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23, Issue:10 Topics: Dialysis; Diazepam; Drug Stability; Freezing; Humans; Imipramine; Immunodiffusion; Lidocaine; Male; Orosomucoid; Phenytoin; Protein Binding; Serum Albumin	1985
A common structural model for central nervous system drugs and their receptors. Journal of medicinal chemistry, 1986, Volume: 29, Issue:4 Topics: Amphetamine; Central Nervous System Agents; Chlorpromazine; Imipramine; Models, Molecular; Molecular Conformation; Phenytoin; Procyclidine; Receptors, Drug; Structure-Activity Relationship	1986
Letter: Amitriptyline and imipramine poisoning in children. British medical journal, 1974, Mar-23, Volume: 1, Issue:5907 Topics: Amitriptyline; Cardiac Complexes, Premature; Child; Humans; Imipramine; Phenytoin; Tachycardia	1974
Cytotoxic effects of imipramine on platelets. Biochemical pharmacology, 1974, Sep-15, Volume: 23, Issue:18 Topics: Animals; Blood Cell Count; Blood Platelets; Calcium Chloride; Chlorpromazine; Creatine Kinase; Edetic Acid; Humans; Imipramine; L-Lactate Dehydrogenase; Magnesium; Male; Ouabain; Phencyclidine; Phenytoin; Rats; Temperature; Thrombin	1974
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism. Molecular pharmacology, 1966, Volume: 2, Issue:4 Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine	1966
Pharmacological properties of 3-dimethylamino-2-methyl-1-phenyl-1-o-tolylpropanol (SK&F 70463-A). The Journal of pharmacy and pharmacology, 1965, Volume: 17, Issue:8 Topics: Amphetamine; Animals; Anticonvulsants; Cats; Chlorpromazine; Diuretics; Dogs; Haplorhini; Imipramine; Phenytoin; Rats	1965
The intracerebral effects of noradrenaline and its modification by drugs in the mouse. The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:9 Topics: Amitriptyline; Animals; Antidepressive Agents; Ataxia; Atropine; Body Temperature; Brain; Central Nervous System; Chlordiazepoxide; Chlorpheniramine; Chlorpromazine; Diazepam; Drug Antagonism; Haloperidol; Histamine H1 Antagonists; Imipramine; Male; Mice; Norepinephrine; Nortriptyline; Pentobarbital; Phenytoin; Piperazines; Trihexyphenidyl	1966
The effect of selected drugs on the "emotional" behavior elicited via hypothalamic stimulation. International journal of neuropharmacology, 1968, Volume: 7, Issue:1 Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Cats; Chlorpromazine; Depression, Chemical; Electric Stimulation; Emotions; Hypothalamus; Imipramine; Meprobamate; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Pregnanediones; Reserpine; Scopolamine; Stimulation, Chemical; Strychnine; Tremorine	1968
Brain uptake of metabolites and drugs following carotid arterial injections. Transactions of the American Neurological Association, 1971, Volume: 96 Topics: Acetates; Amino Acids; Animals; Antipyrine; Ascorbic Acid; Aspirin; Barbiturates; Blood-Brain Barrier; Brain; Caffeine; Chloroquine; Cyanides; Ethanol; Imipramine; Lactates; Mescaline; Morphine; Neurotransmitter Agents; Nicotine; Penicillin G; Pharmaceutical Preparations; Phenytoin; Procaine; Pyruvates; Rats	1971
Significance of withdrawal jumping response in predicting physical dependence in mice. Japanese journal of pharmacology, 1973, Volume: 23, Issue:3 Topics: Amitriptyline; Animals; Atropine; Cannabis; Chlordiazepoxide; Chlorpromazine; Diazepam; Humans; Imipramine; Male; Mephenesin; Methamphetamine; Mice; Morphine Dependence; Naloxone; Pentobarbital; Perphenazine; Phenytoin; Reserpine; Substance Withdrawal Syndrome	1973
The management of imipramine (Tofranil) intoxication in children. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, May-19, Volume: 47, Issue:19 Topics: Adult; Anticonvulsants; Arrhythmias, Cardiac; Electrocardiography; Emergencies; Female; Gastric Lavage; Heart Arrest; Humans; Imipramine; Infant; Infusions, Parenteral; Intensive Care Units; Male; Neostigmine; Oxygen Inhalation Therapy; Phenytoin; Pyridostigmine Bromide; Respiration, Artificial; Resuscitation	1973
Letter: Amitriptyline and imipramine poisoning in children. British medical journal, 1974, Apr-20, Volume: 2, Issue:5911 Topics: Amitriptyline; Antidotes; Child; Enuresis; Humans; Imipramine; Phenytoin; Physostigmine	1974
Letter: Amitriptyline and imipramine poisoning in children. British medical journal, 1974, Jun-01, Volume: 2, Issue:5917 Topics: Amitriptyline; Child; Enuresis; Heart Diseases; Humans; Imipramine; Phenytoin; Poisoning	1974
[Changes in the effect of drugs due to reciprocal interference with their protein binding and catabolism]. Deutsche medizinische Wochenschrift (1946), 1974, Mar-01, Volume: 99, Issue:9 Topics: Adult; Animals; Anticoagulants; Barbiturates; Cytochrome P-450 Enzyme System; Dogs; Dose-Response Relationship, Drug; Drug Antagonism; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Endoplasmic Reticulum; Enzyme Induction; Female; Gluconates; Humans; Imipramine; Kidney; Liver; Metabolic Clearance Rate; Pharmaceutical Preparations; Phenytoin; Protein Binding; Rabbits; Rats; Time Factors	1974
[Cardiac toxicity of tricyclic antidepressants]. Giornale italiano di cardiologia, 1972, Volume: 2, Issue:3 Topics: Adult; Antidepressive Agents; Arrhythmias, Cardiac; Coronary Disease; Electrocardiography; Female; Heart Conduction System; Humans; Hypotension; Imipramine; Mental Disorders; Middle Aged; Phenothiazines; Phenytoin; Time Factors	1972
[Dialysis of drugs and poisons. 2]. Medizinische Klinik, 1972, Nov-03, Volume: 67, Issue:44 Topics: Acetaminophen; Aminopyrine; Amitriptyline; Aspirin; Carbamazepine; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Heroin; Humans; Imipramine; Lithium; Pargyline; Pentazocine; Phenacetin; Phenelzine; Phenytoin; Poisoning; Primidone; Promazine; Renal Dialysis; Salicylates; Tranylcypromine; Trifluoperazine	1972
Observations on models used for the evaluation of antiarrhythmic drugs. Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 193, Issue:1 Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atropine; Benzazepines; Bretylium Compounds; Chlorpheniramine; Diazepam; Disease Models, Animal; Dogs; Drug Antagonism; Guinea Pigs; Imipramine; Ketones; Lidocaine; Male; Meperidine; Mephentermine; Ouabain; Phentolamine; Phenytoin; Procainamide; Promazine; Promethazine; Propranolol; Quinidine	1971
A comparison of the binding of drugs to adult and cord plasma. European journal of clinical pharmacology, 1971, Volume: 4, Issue:1 Topics: Blood; Blood Proteins; Carbon Isotopes; Cephaloglycin; Cephalothin; Chromatography, Thin Layer; Dialysis; Diazoxide; Female; Freezing; Humans; Imipramine; Infant, Newborn; Pharmaceutical Preparations; Phenytoin; Pregnancy; Protein Binding; Umbilical Cord	1971
Aconitine-induced writhing: a method for assessment of analgesic activity. Japanese journal of pharmacology, 1969, Volume: 19, Issue:1 Topics: Aconitum; Analgesics; Animals; Aspirin; Behavior, Animal; Chlorpromazine; Imipramine; Mephenesin; Methaqualone; Methods; Mice; Morphine; Phenoxybenzamine; Phenylbutazone; Phenytoin; Sodium Salicylate	1969
Plasma protein binding of tricyclic anti-depressants in man. Biochemical pharmacology, 1969, Volume: 18, Issue:9 Topics: Amitriptyline; Antidepressive Agents; Blood Proteins; Carbon Isotopes; Desipramine; Humans; Imipramine; Nortriptyline; Phenytoin; Protein Binding; Temperature; Tritium	1969
[Introduction of mass psychology of animals to pharmacology. 2. New screening method of drugs acting on the central nervous system]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1969, Jul-20, Volume: 65, Issue:4 Topics: Aminobutyrates; Amphetamine; Animals; Anticonvulsants; Behavior, Animal; Carbamates; Chlordiazepoxide; Chlorpromazine; Diphenhydramine; Imidazoles; Imipramine; Male; Mice; Phenobarbital; Phenytoin; Reserpine; Tranquilizing Agents	1969
[Anticonvulsant action of imipramine and imitriptyline associated with phenobarbital, phenytoin and diazepam]. Revue neurologique, 1970, Volume: 123, Issue:2 Topics: Amitriptyline; Animals; Anticonvulsants; Diazepam; Electroshock; Imipramine; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures	1970
Effects of various drugs on the uterotropic response to mestranol and norethynodrel in the rat. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 136, Issue:1 Topics: Aminosalicylic Acids; Animals; Chlorpromazine; Drug Synergism; Female; Imipramine; Mestranol; Norethynodrel; Organ Size; Phenobarbital; Phenylbutazone; Phenytoin; Proadifen; Rats; Scopolamine; Tolbutamide; Uterus	1971
[Depressive syndromes in childhood and adolescence. Symptomatology, etiology and prognosis]. Monographien aus dem Gesamtgebiete der Psychiatrie, 1971, Volume: 4 Topics: Adolescent; Age Factors; Child; Child Development; Child Psychiatry; Child, Hospitalized; Child, Preschool; Convulsive Therapy; Depression; Dibenzazepines; Family; Female; Follow-Up Studies; Humans; Imipramine; Infant; Intelligence; Male; Mother-Child Relations; Phenytoin; Psychosexual Development; Psychotherapy; Psychotherapy, Group; Schizophrenia, Childhood; Sex Factors; Sibling Relations; Suicide; Tranquilizing Agents	1971
Growth hormone secretion during sleep. The Journal of clinical investigation, 1968, Volume: 47, Issue:9 Topics: Adult; Blood Glucose; Chlordiazepoxide; Chlorpromazine; Electroencephalography; Eye Movements; Female; Growth Hormone; Humans; Hydrocortisone; Imipramine; Insulin; Isocarboxazid; Male; Phenobarbital; Phenytoin; Secretory Rate; Sleep	1968
[Pharmacologic properties of partially purified glutamic acid decarboxylase (L-glutamate-1-carboxylyase, E.C. 4.1.1.15) from calf cerebral cortex]. Helvetica physiologica et pharmacologica acta, 1968, Volume: 26, Issue:3 Topics: Animals; Antidepressive Agents; Barbiturates; Carboxy-Lyases; Cattle; Cerebral Cortex; Chemical Phenomena; Chemistry; Chlorpromazine; Codeine; Glutamates; Hydantoins; Imipramine; Lysergic Acid Diethylamide; Phenethylamines; Phenytoin; Primidone; Psilocybin; Pyrrolidines; Spectrophotometry	1968
Hematologic complications from tranquilizers in children. Southern medical journal, 1968, Volume: 61, Issue:10 Topics: Adolescent; Age Factors; Agranulocytosis; Bone Marrow Examination; Brain Damage, Chronic; Brain Diseases; Child; Dextroamphetamine; Eosinophilia; Female; Fluphenazine; Humans; Imipramine; Leukocyte Count; Leukocytosis; Leukopenia; Male; Methylphenidate; Phenobarbital; Phenytoin; Sex Factors; Thioridazine; Tranquilizing Agents	1968
The influence of disulfiram and calcium carbimide on the serum diphenylhydantoin. Excretion of HPPH in the urine. Archives of neurology, 1967, Volume: 16, Issue:6 Topics: Acetazolamide; Adult; Aged; Alcoholism; Amitriptyline; Chlordiazepoxide; Chlorpromazine; Chromatography, Thin Layer; Cyanates; Disulfiram; Drug Synergism; Epilepsy; Humans; Hydroflumethiazide; Imipramine; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone	1967
Effect of some anticonvulsant drugs on the spinal trigeminal nucleus. Neurology, 1967, Volume: 17, Issue:3 Topics: Animals; Anticonvulsants; Blood Pressure; Body Temperature; Cats; Chloralose; Electric Stimulation; Electrophysiology; Imipramine; Maxillary Nerve; Neurons; Pentobarbital; Phenobarbital; Phenytoin; Spinal Cord; Trigeminal Nerve	1967
[Pharmacology of a 1H-1, 2, 4-triazolyl benzophenone derivative (450191-S), a new sleep-inducer (III). Behavioral study on interactions of 450191-S and other drugs in mice]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1984, Volume: 84, Issue:2 Topics: Aminopyrine; Animals; Anti-Anxiety Agents; Apomorphine; Behavior, Animal; Benzodiazepines; Central Nervous System; Central Nervous System Agents; Haloperidol; Hypnotics and Sedatives; Imipramine; Male; Mice; Pentylenetetrazole; Phenytoin; Reserpine; Triazoles	1984
Treatment of bulimia. Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:11 Topics: Adolescent; Adult; Combined Modality Therapy; Feeding and Eating Disorders; Female; Humans; Hyperphagia; Imipramine; Phenytoin; Psychotherapy	1983
The binding of chemically different psychotropic drugs to alpha 1-acid glycoprotein. Pharmacopsychiatria, 1983, Volume: 16, Issue:3 Topics: Diazepam; Haloperidol; Humans; Imipramine; Kinetics; Orosomucoid; Perazine; Phenobarbital; Phenytoin; Protein Binding; Psychotropic Drugs; Structure-Activity Relationship	1983
Phenytoin: similarity to tricyclic antidepressants. Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:3 Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chlordiazepoxide; Conditioning, Operant; Cues; Desipramine; Discrimination Learning; Imipramine; Male; Pentobarbital; Phenytoin; Rats; Rats, Inbred Strains	1983
Tricyclic antidepressant poisoning and prolonged external cardiac massage during asystole. British medical journal (Clinical research ed.), 1981, Dec-05, Volume: 283, Issue:6305 Topics: Humans; Imipramine; Phenytoin; Seizures	1981
Some further observations on the stimulation by high external potassium of the sodium efflux in barnacle muscle fibers. Pflugers Archiv : European journal of physiology, 1982, Volume: 395, Issue:4 Topics: Animals; Chelating Agents; Fluorides; Imipramine; Muscles; Phenothiazines; Phenytoin; Potassium; Purine Nucleotides; Sodium; Stimulation, Chemical; Thoracica; Verapamil	1982
Effects of indeloxazine HCl on kindled amygdaloid seizures in rats: comparison with the effects of phenytoin, diazepam, ethanol, and imipramine. Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:2 Topics: Animals; Anticonvulsants; Diazepam; Ethanol; Imipramine; Kindling, Neurologic; Male; Morpholines; Phenytoin; Rats; Rats, Wistar	1993