imipramine and phencyclidine

imipramine has been researched along with phencyclidine in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199017 (58.62)18.7374
1990's3 (10.34)18.2507
2000's8 (27.59)29.6817
2010's1 (3.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM1
Abraham, MH; Acree, WE; Ibrahim, A1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Henriksson, BG; Järbe, TU; Johansson, JO1
Rayport, S; Sulzer, D1
Ishikawa, K; Kameyama, T; Nabeshima, T; Yamaguchi, K; Yoshida, S1
Ohno, Y; Warnick, JE1
Furukawa, H; Kameyama, T; Nabeshima, T; Yamaguchi, K; Yoshida, S1
Tonge, SR2
Goode, DJ; Meltzer, HY1
Lees, H2
Leonard, BE; Tonge, SR2
Domino, EF; Wilson, AE1
Lees, H; Loncharich, K1
Sharman, DF1
Nakajima, H; Thuillier, J1
Aronstam, RS1
Abbassy, MA; Ei-Fakahany, EF; Eldefrawi, AT; Eldefrawi, ME; Miller, ER1
Attali, G; Gil-Ad, I; Rehavi, M; Weizman, A1
De La Garza, R; Jentsch, JD; Roth, RH; Verrico, CD1
Arias, HR; Bouzat, C; Gumilar, F; Spitzmaul, G1
Barnouin, MC; Chabot, C; Depoortere, R; Griebel, G; Perrault, G; Scatton, B; Terranova, JP1

Reviews

1 review(s) available for imipramine and phencyclidine

ArticleYear
The role of receptor binding in drug discovery.
    Journal of natural products, 1993, Volume: 56, Issue:4

    Topics: Animals; Drug Design; Humans; Receptors, Drug

1993

Other Studies

28 other study(ies) available for imipramine and phencyclidine

ArticleYear
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Drug discrimination in rats: the effects of phencyclidine and ditran.
    Psychopharmacologia, 1975, Apr-30, Volume: 42, Issue:1

    Topics: Animals; Cues; Cyclohexylamines; Discrimination Learning; Drug Combinations; Fenclonine; Glycolates; Imipramine; Ketamine; Male; Neostigmine; Phencyclidine; Physostigmine; Piperidines; Pyrrolidines; Rats; Tacrine; Tetrabenazine; Yohimbine

1975
Amphetamine and other psychostimulants reduce pH gradients in midbrain dopaminergic neurons and chromaffin granules: a mechanism of action.
    Neuron, 1990, Volume: 5, Issue:6

    Topics: Amphetamine; Animals; Cells, Cultured; Chromaffin Granules; Cocaine; Dopamine; Fenfluramine; Hydrogen-Ion Concentration; Imipramine; Immunoenzyme Techniques; Mesencephalon; Microscopy, Electron; Neurons; Phencyclidine; Psychotropic Drugs; Rats; Serotonin; Tyramine

1990
Phencyclidine-induced head-weaving and head-twitch through interaction with 5-HT1 and 5-HT2 receptors in reserpinized rats.
    Neuropharmacology, 1987, Volume: 26, Issue:10

    Topics: Animals; Brain; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Male; Methoxydimethyltryptamines; p-Chloroamphetamine; Phencyclidine; Pindolol; Piperidines; Rats; Rats, Inbred F344; Receptors, Serotonin; Reserpine; Ritanserin; Serotonin; Serotonin Antagonists; Stereotyped Behavior

1987
Presynaptic activation of the spinal serotonergic system in the rat by phencyclidine in vitro.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:1

    Topics: 5,7-Dihydroxytryptamine; Animals; Animals, Newborn; Imipramine; Male; p-Chloroamphetamine; Phencyclidine; Rats; Rats, Inbred Strains; Reflex; Serotonin; Spinal Cord; Synapses

1989
Phencyclidine-induced wet-dog shakes observed in rats after withdrawal from reserpine treatment.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:5

    Topics: Animals; Behavior, Animal; Imipramine; Male; Mianserin; p-Chloroamphetamine; Phencyclidine; Rats; Rats, Inbred F344; Reserpine; Serotonin; Substance Withdrawal Syndrome

1986
Permanent changes in brain monoamine metabolism induced by the administration of psychotropic drugs during the pre- and neonatal periods in rats.
    The Journal of pharmacy and pharmacology, 1972, Volume: 24

    Topics: Animals; Ascorbic Acid; Brain; Brain Chemistry; Chlorpromazine; Female; Hydroxyindoleacetic Acid; Imipramine; Male; Methamphetamine; Norepinephrine; Phencyclidine; Pregnancy; Rats; Serotonin

1972
Catecholamine concentrations in discrete areas of the rat brain after the pre- and neonatal administration of phencyclidine and imipramine.
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:2

    Topics: Amygdala; Animals; Animals, Newborn; Ascorbic Acid; Brain Chemistry; Catecholamines; Cerebellar Cortex; Dopamine; Female; Hippocampus; Hypothalamus; Imipramine; Male; Norepinephrine; Phencyclidine; Pons; Pregnancy; Rats; Tectum Mesencephali

1973
Cytotoxic effects of imipramine on platelets.
    Biochemical pharmacology, 1974, Sep-15, Volume: 23, Issue:18

    Topics: Animals; Blood Cell Count; Blood Platelets; Calcium Chloride; Chlorpromazine; Creatine Kinase; Edetic Acid; Humans; Imipramine; L-Lactate Dehydrogenase; Magnesium; Male; Ouabain; Phencyclidine; Phenytoin; Rats; Temperature; Thrombin

1974
Alteration of liver glutamic dehydrogenase by chlorpromazine.
    Biochemical pharmacology, 1971, Volume: 20, Issue:1

    Topics: Amination; Amines; Animals; Cattle; Chemical Phenomena; Chemistry; Chlorpromazine; Glutamate Dehydrogenase; Glutamates; Hydrogen-Ion Concentration; Imipramine; Ketoglutaric Acids; Kinetics; Liver; Mitochondria, Liver; NAD; Oxidative Phosphorylation; Oxygen Consumption; Phencyclidine; Pyruvates; Rats; Spectrophotometry; Ultraviolet Rays; Uncoupling Agents

1971
Some persistent effects of the pre- and neonatal administration of psychotropic drugs on noradrenaline metabolism in discrete areas of rat brain.
    British journal of pharmacology, 1973, Volume: 48, Issue:2

    Topics: Amygdala; Animals; Animals, Newborn; Antidepressive Agents; Brain; Cerebral Cortex; Chlorpromazine; Corpus Striatum; Female; Fetus; Hippocampus; Hypothalamus; Imipramine; Medulla Oblongata; Mesencephalon; Methamphetamine; Norepinephrine; Phencyclidine; Pons; Pregnancy; Rats; Thalamus; Tranquilizing Agents

1973
Partial antagonism of the behavioural and neurochemical effects of phencyclidine by drugs affecting monoamine metabolism.
    Psychopharmacologia, 1972, Volume: 24, Issue:4

    Topics: Anesthetics; Animals; Brain; Drug Antagonism; Hallucinogens; Hydroxyindoleacetic Acid; Imipramine; Injections, Intraperitoneal; Phencyclidine; Piperidines; Rats; Serotonin; Tetrabenazine

1972
Psychotropic drug influences on brain acetylcholine utilization.
    Psychopharmacologia, 1972, Volume: 25, Issue:4

    Topics: Acetylcholine; Animals; Antidepressive Agents; Brain; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Hemicholinium 3; Imipramine; Lysergic Acid Diethylamide; Male; Methotrimeprazine; Morphine; Pentobarbital; Phencyclidine; Rats; Rats, Inbred Strains; Scopolamine; Tranquilizing Agents

1972
The influence of pH on the effects in vitro of some organic cations and anions on oxidative phosphorylation.
    Biochimica et biophysica acta, 1965, Jul-29, Volume: 105, Issue:1

    Topics: Anesthetics; Animals; Chlorides; Dinitrophenols; Hydrogen-Ion Concentration; Imipramine; In Vitro Techniques; Ions; Liver; Mitochondria; Oxidative Phosphorylation; Phencyclidine; Rats; Surface-Active Agents

1965
The influence of pH on the effects in vitro of some organic cations and anions on mitochondrial respiration.
    Biochimica et biophysica acta, 1966, Jan-11, Volume: 113, Issue:1

    Topics: Anesthetics; Animals; Chlorpromazine; Hydrogen-Ion Concentration; Imipramine; In Vitro Techniques; Ions; Liver; Mitochondria; Phencyclidine; Rats; Surface-Active Agents

1966
Changes in the metabolism of 3,4-dihydroxyphenylethylamine (dopamine) in the striatum of the mouse induced by drugs.
    British journal of pharmacology and chemotherapy, 1966, Volume: 28, Issue:2

    Topics: Anesthetics; Animals; Behavior, Animal; Brain; Dopamine; Drug Antagonism; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Methylphenidate; Methyltyrosines; Mice; Mixed Function Oxygenases; Monoamine Oxidase; Morphine; Parasympatholytics; Parasympathomimetics; Pargyline; Phencyclidine; Phenylacetates; Pilocarpine; Probenecid; Reserpine; Tolazoline; Tranquilizing Agents; Tyrosine; Zoxazolamine

1966
[Neuropharmacologic similarities and differences between the hallucinogens and the antidepressants].
    Arzneimittel-Forschung, 1966, Volume: 16, Issue:2

    Topics: Animals; Antidepressive Agents; Electrocardiography; Electroencephalography; Electromyography; Hallucinogens; Imipramine; Lysergic Acid Diethylamide; Phencyclidine; Psilocybin; Rabbits; Serotonin

1966
Interactions of tricyclic antidepressants with a synaptic ion channel.
    Life sciences, 1981, Jan-05, Volume: 28, Issue:1

    Topics: Acetylcholine; Amitriptyline; Amphibian Venoms; Animals; Antidepressive Agents, Tricyclic; Binding Sites; Desipramine; Electric Organ; Fishes; Imipramine; Ion Channels; Nortriptyline; Phencyclidine; Receptors, Nicotinic

1981
Alcohol modulation of drug binding to the channel sites of the nicotinic acetylcholine receptor.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 224, Issue:2

    Topics: Alcohols; Amphibian Venoms; Animals; Carbachol; Drug Interactions; Imipramine; Ion Channels; Membranes; Naphthols; Phencyclidine; Receptors, Cholinergic; Torpedo

1983
Opposite modulatory effects of ovarian hormones on rat brain dopamine and serotonin transporters.
    Brain research, 1997, May-09, Volume: 756, Issue:1-2

    Topics: Animals; Brain; Carrier Proteins; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Estradiol; Female; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Ovariectomy; Phencyclidine; Progesterone; Rats; Rats, Inbred Strains; Serotonin Plasma Membrane Transport Proteins

1997
Adaptation of monoaminergic responses to phencyclidine in nucleus accumbens and prefrontal cortex following repeated treatment with fluoxetine or imipramine.
    Brain research, 2002, Dec-20, Volume: 958, Issue:1

    Topics: Adaptation, Physiological; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Biogenic Monoamines; Depressive Disorder; Dopamine; Excitatory Amino Acid Antagonists; Fluoxetine; Imipramine; Male; Neostriatum; Nucleus Accumbens; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Selective Serotonin Reuptake Inhibitors; Serotonin

2002
Molecular mechanisms of inhibition of nicotinic acetylcholine receptors by tricyclic antidepressants.
    Neuropharmacology, 2003, Volume: 45, Issue:7

    Topics: Acetylcholine; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cell Membrane; Doxepin; Excitatory Amino Acid Antagonists; Humans; Imipramine; In Vitro Techniques; Kidney; Kinetics; Membrane Potentials; Mice; Nicotinic Antagonists; Patch-Clamp Techniques; Phencyclidine; Receptors, Nicotinic; Torpedo

2003
SSR181507, a dopamine D(2) receptor antagonist and 5-HT(1A) receptor agonist, alleviates disturbances of novelty discrimination in a social context in rats, a putative model of selective attention deficit.
    Psychopharmacology, 2005, Volume: 181, Issue:1

    Topics: Age Factors; Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Clozapine; Dextroamphetamine; Dioxanes; Discrimination, Psychological; Disease Models, Animal; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; Imipramine; Injections, Intraperitoneal; Male; Phencyclidine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D2; Recognition, Psychology; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Social Behavior; Tacrine; Tropanes

2005