imipramine has been researched along with paroxetine in 201 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (14.43) | 18.7374 |
| 1990's | 96 (47.76) | 18.2507 |
| 2000's | 40 (19.90) | 29.6817 |
| 2010's | 33 (16.42) | 24.3611 |
| 2020's | 3 (1.49) | 2.80 |
| Authors | Studies |
|---|---|
| Costanzo, MJ; Maryanoff, BE; McComsey, DF; Nortey, SO; Shank, RP; Vaught, JL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Buck, LB; Petrascheck, M; Ye, X | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Buckley, DB; Funk, RS; Hensley, T; Kazmi, F; Loewen, GJ; Parkinson, A; Pope, C | 1 |
| Dalvie, D; Loi, CM; Smith, DA | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Artursson, P; Mateus, A; Matsson, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Baba, S; Horisawa, T; Kato, T; Kinomura, N; Kodo, T; Koyama, K; Masumoto, S; Matsumoto, K; Matsumoto, Y; Oki, H; Yabuuchi, K; Yoshinaga, H | 1 |
| Alonso, C; Campillo, NE; Cuesta-Geijo, MÁ; Delgado, R; Gil, C; Ginex, T; Morales-Tenorio, M; Muñoz-Fontela, C | 1 |
| Chen, W; Han, S; Hu, Y; Li, H; Tong, X; Yang, L; Zuo, J | 1 |
| Bach, FW; Gram, LF; Sindrup, SH | 1 |
| Block, P; Fieve, RR; Peselow, ED; Robins, CJ; Sanfilipo, MP | 1 |
| Difiglia, C; Fieve, RR; Peselow, ED; Sanfilipo, MP | 1 |
| Feighner, JP | 1 |
| Bahr, B; Borup, A; Calberg, H; Christiansen, PE; Larsen, SB; Loldrup, D; Nilakantan, B; Ohrberg, S; Severin, B; Søgaard, J | 1 |
| Fabre, LF | 1 |
| Boyer, WF; Feighner, JP | 2 |
| Blumhardt, CL; Overweg, N; Shrivastava, RK; Shrivastava, SH | 1 |
| Cohn, JB; Wilcox, CS | 1 |
| Karnovsky, ML; Polanski, M | 1 |
| Ben-Zeev, A; Lerer, B; Newman, ME | 1 |
| Clissold, SP; Dechant, KL | 1 |
| Mellerup, ET; Plenge, P | 6 |
| Laursen, H; Mellerup, ET; Plenge, P | 2 |
| Egashira, T; Goto, S; Yamanaka, Y | 1 |
| Larsen, T; Manniche, PM; Morsing, I; Møller, SE; Nielsen, OA; Petersen, JS; Skausig, OB | 1 |
| Cohn, JB; Dunbar, GC; Fabre, LF; Feighner, JP; Fieve, RR; Mendels, J; Shrivastava, RK | 2 |
| Briley, M; Moret, C | 2 |
| Dam, H; Lauritzen, L; Mellerup, ET; Plenge, P | 1 |
| Blier, P; Chaput, Y; de Montigny, C | 1 |
| Foy, B; Hepner, A; Hrdina, PD; Summers, RJ | 1 |
| Koe, BK; Lebel, LA; Welch, WM | 1 |
| Cohn, JB; Crowder, JE; Ryan, PJ; Wilcox, CS | 1 |
| Brøsen, K; Eshøj, O; Gram, LF; Mogensen, EF; Sindrup, SH | 1 |
| Westwick, F | 1 |
| Egashira, T; Goto, S; Murayama, F; Yamanaka, Y | 1 |
| Brunello, N; Galimberti, R; Racagni, G; Riva, M; Rovescalli, AC | 1 |
| De Oliveira, AM; Langer, SZ; Schoemaker, H; Segonzac, A | 1 |
| Galzin, AM; Langer, SZ; Rocca, P | 1 |
| Esnaud, H; Graham, D; Habert, E; Langer, SZ | 1 |
| Barouche, F; Fieve, RR; Filippi, AM; Goodnick, P; Peselow, ED | 2 |
| Barouche, F; Fieve, RR; Filippi, AM; Goodnick, P; Peselow, ED; Stanley, M | 1 |
| Galzin, AM; Langer, SZ; Moret, C; Verzier, B | 1 |
| Honoré, PL; Honoré, T; Mellerup, ET; Plenge, P | 1 |
| Asberg, M; Eriksson, B; Mårtensson, B; Träskman-Bendz, L; Wägner, A | 1 |
| Agid, Y; Cash, R; Raisman, R | 1 |
| Langer, SZ; Schoemaker, H; Segonzac, A | 1 |
| Mellerup, ET; Plenge, P; Rafaelsen, OJ | 1 |
| Ishikura, Y; Ono, H; Yokota, S | 1 |
| Galzin, AM; Langer, SZ | 1 |
| Bergström, M; Eriksson, K; Marcusson, JO; Ross, SB | 1 |
| Eriksson, K; Marcusson, J | 1 |
| Cortés, R; Palacios, JM; Pazos, A; Probst, A; Soriano, E | 1 |
| Gleiter, CH; Nutt, DJ | 1 |
| Galzin, AM; Langer, SZ; Lee, CR; Taranger, MA | 1 |
| Galzin, AM; Langer, SZ; Loo, H; Poirier, MF; Sechter, D; Zarifian, E | 1 |
| Mellerup, ET; Nielsen, M; Plenge, P | 1 |
| Engelstoft, M; Mellerup, ET; Plenge, P | 1 |
| Erreboe, I; Mellerup, ET; Plenge, P | 1 |
| Owens, DW | 1 |
| Dunbar, GC; Dunner, DL; Montgomery, SA | 1 |
| Preskorn, SH | 1 |
| Helmeste, DM; Reist, C; Tang, SW; Vu, R | 1 |
| Iny, L; Luthe, L; Pecknold, JC; Ramdoyal, D | 1 |
| Freemantle, N; House, A; Mason, J; Sheldon, T; Song, F | 1 |
| Hirschfeld, RM | 1 |
| Asou, T; Hayashida, M; Minami, H; Nakane, Y; Tateishi, T; Togita, M; Tsujimura, T | 1 |
| O'Brien, JT | 1 |
| Falkowski, J; Horton, RW; Jacobson, RR; Lawrence, KM | 1 |
| Cassano, GB; Giannaccini, G; Lucacchini, A; Marazziti, D; Martini, C; Quattrone, C; Rotondo, A | 1 |
| Bebbington, PE; Jönsson, B | 1 |
| Craighead, WE; Franks, J; Knight, DL; Krishnan, KR; Nemeroff, CB | 1 |
| Alpert, JE; Fava, M; Maddocks, A; Rosenbaum, JF | 1 |
| Härtter, S; Hermes, B; Hiemke, C; Szegedi, A | 1 |
| Asai, K; Mori, H; Nankai, M; Toru, M; Watanabe, A; Yamada, S; Yoshimoto, S | 1 |
| Farthing, MJ; Gorard, DA; Libby, GW | 1 |
| Arminen, SL; Ikonen, U; Koponen, H; Korpela, V; Kourula, K; Lehtonen, ML; Leinonen, E; Mahlanen, A; Pulkkinen, P; Ryyppö, J | 1 |
| Claghorn, JL; Feighner, JP | 1 |
| Faludi, G; Tekes, K; Tóthfalusi, L | 1 |
| Chudzik, J; Strijewski, A; Tang, SW | 1 |
| McEwen, BS; Mendelson, S; Sakai, RR; Watanabe, Y | 1 |
| Kupfer, DJ | 1 |
| Arora, RC; Crayton, J; Gulati, A | 1 |
| Arora, RC; Crayton, JW; Gulati, A | 1 |
| Dewar, KM; Grondin, L; Nénonéné, EK; Ohayon, M; Reader, TA | 1 |
| Bentkover, J; Lapierre, Y; Manners, S; Schainbaum, S | 1 |
| Bolwig, TG; Dam, H; Mellerup, ET; Plenge, P | 1 |
| Bertholon, F; el Allali, A; Krajewski, Y | 1 |
| Gurevich, EV; Joyce, JN | 1 |
| Chan, CH; Chiu, HJ; Hong, CJ | 1 |
| Betti, L; Cassano, GB; Chiellini, G; Giannaccini, G; Lucacchini, A; Marazziti, D; Martin, C; Rotondo, A | 1 |
| Bijak, M; Dziedzicka-Wasylewska, M; Maj, J; Rogoz, R; Rogóz, Z; Skuza, G; Tokarski, T | 1 |
| McCook, EC; Ritchie, JC; Seidler, FJ; Slotkin, TA | 1 |
| Cooper, TB; Costa, E; Guidotti, A; Uzunov, DP | 1 |
| Bech, P; Black, C; Clemmesen, L; Lauritzen, L; Lunde, M; Odgaard, K; Ohrström, J | 1 |
| Albers, LJ; Helmeste, D; Reist, C; Tang, SW; Vu, R | 1 |
| Bourin, M; Pinot, P; Redrobe, JP | 1 |
| Carroll, BJ; McCook, EC; Ritchie, JC; Seidler, FJ; Slotkin, TA | 1 |
| Hayashi-Kuwabara, Y; Ikeda, Y; Izumi, J; Kiuchi, Y; Oguchi, K; Tanaka, Y; Washizuka, M; Yoshinaga, K | 1 |
| Alvarez, P; Arranz, B; Cortadellas, T; Menchon, JM; Navarro, MA; Oros, M; Rosel, P; Vallejo, J | 1 |
| Brink, DD; Carroll, NV; Farrar, TW; Kirkwood, CK; Melton, ST | 1 |
| Alvarez, P; Arranz, B; Lirón, F; Menchón, JM; Navarro, MA; Rosel, P; Vallejo, J | 1 |
| Fonzo, V; Ravizza, L; Rocca, P; Scotta, M; Zanalda, E | 1 |
| Ahern, D; Ball, SE; Kao, J; Scatina, J | 1 |
| Rizzo, JA; Woods, SW | 1 |
| Boyer, W | 1 |
| Flint, A | 1 |
| McKay, CA; Tilden, FF; Weiner, AL | 1 |
| Becker, A; Franke, C; Grecksch, G; Huether, G; Sabel, B; Schröder, U; Zhou, D | 1 |
| Alvarez, P; Arranz, B; Menchón, JM; Navarro, MA; Oros, M; Rosel, P; Vallejo, J | 1 |
| Costentin, J; Passera, G; Vaugeois, JM; Zuccaro, F | 1 |
| Falkowski, J; Horton, RW; Jacobson, RR; Lawrence, KM; Lowther, S | 1 |
| Bergam, K; Claypoole, K; Elliott, AJ; Roy-Byrne, PP; Russo, J; Uldall, KK | 1 |
| Bray, J; Hunter, BN; Katona, CL | 1 |
| Bovier, P; Karege, F; Malafosse, A; Stepanian, R | 1 |
| Arranz, B; Crespo, JM; Menchon, JM; Navarro, MA; Oros, M; Rosel, P; Vallejo, J | 1 |
| Vermeulen, T | 1 |
| Aguilera, J; Gil, C; Inserte, J; Najib, A; Pelliccioni, P | 1 |
| Kellermann, O; Launay, JM; Loric, S; Mutel, V | 1 |
| Cohen, LJ | 1 |
| Bentkover, JD; Feighner, JP | 1 |
| Kristensen, AS; Mortensen, OV; Rudnick, G; Wiborg, O | 1 |
| Blier, P; de Montigny, C; Haddjeri, N; Szabo, ST | 1 |
| Arancio, C; Bellodi, L; Bertani, A; Caldirola, D; Perna, G | 1 |
| Akiskal, HS; Frare, F; Mata, B; Mengali, F; Perugi, G; Recchia, M; Serra, G; Toni, C; Vitale, B | 1 |
| Bourin, M; David, DJ; Hascoët, M; Jolliet, P; Nic Dhonnchadha, BA | 1 |
| Borsini, F; Brambilla, A; Cesana, R; Grippa, N | 1 |
| Bowden, CL; Evans, DL; Gergel, IP; Gyulai, L; Nemeroff, CB; Oakes, R; Pitts, CD; Sachs, GS | 1 |
| Emslie, GJ; Mayes, TL | 1 |
| Birmaher, B; Carlson, GA; Clarke, GN; Emslie, GJ; Feinberg, D; Geller, B; Hagino, OR; Keller, MB; Klein, RG; Koplewicz, H; Kusumakar, V; Kutcher, SP; McCafferty, JP; Oakes, R; Papatheodorou, G; Ryan, ND; Sack, WH; Strober, M; Sweeney, M; Wagner, KD; Weller, EB; Winters, NC | 1 |
| Misane, I; Ogren, SO | 1 |
| Barbagli, B; Boissard, R; Fort, P; Gervasoni, D; Henninot, V; Luppi, PH; Panconi, E | 1 |
| Arranz, B; Navarro, MA; Oros, M; Rosel, P; San, L; Urretavizcaya, M; Vallejo, J | 1 |
| Correll, CU; Pleak, RR | 1 |
| Jainer, AK; Silveira, R; Singh, R | 1 |
| De Baets, M; Kenis, G; Maes, M; Steinbusch, H | 1 |
| Harvey, BH; Rosenberg, R; Volke, V; Wegener, G | 1 |
| Gorman, JM | 1 |
| Gaisler-Salomon, I; Green, A; Joel, D; Schiller, D; Weiner, I | 1 |
| Bourin, M; Dailly, E; David, DJ; Hascoët, M; Ripoll, N | 1 |
| Callebert, J; Chabane, N; Delorme, R; Falissard, B; Launay, JM; Leboyer, M; Mouren-Siméoni, MC; Rouillon, F | 1 |
| Bateman, DN; Chick, J; Good, AM; Kelly, CA; Masterton, G | 1 |
| Andrews, G; Carter, R; Donnelly, M; Haby, MM; Heuzenroeder, L; Mihalopoulos, C; Rossell, R; Vos, T | 1 |
| Doljansky, J; Joel, D; Rehavi, M; Roz, N | 1 |
| Calviño, MA; Iscla, IR; Szczupak, L | 1 |
| Cunha, A; Gazalle, FK; Kapczinski, F; Lima, MS; Schmitt, R; Souza, J | 1 |
| Betancur, C; Callebert, J; Chabane, N; Delorme, R; Laplanche, JL; Launay, JM; Leboyer, M; Mouren-Simeoni, MC | 1 |
| Hasegawa, H; Hirose, S; Lin, QS; Nakamura, K; Nishimura, H; Ohashi, A; Ohtsuji, M; Sawabe, K; Sugawara, Y; Tsurui, H; Xiu, Y | 1 |
| Bourin, M; Chenu, F; Dailly, E | 1 |
| Hotte, M; Jay, TM; Naudon, L | 1 |
| Heerdink, ER; van Dijk, L; Volkers, AC | 1 |
| Barlow, DH; Gorman, JM; McHugh, RK; Otto, MW; Shear, MK; Woods, SW | 1 |
| Ikenouchi-Sugita, A; Nakamura, J; Yoshimura, R | 1 |
| Malviya, M; Nadgir, SM | 1 |
| Pinhasov, A; Rehavi, M; Reichenstein, M | 1 |
| Aburakawa, Y; Aizawa, H; Hasebe, N; Kwak, S; Sawada, J; Yamashita, T | 1 |
| Aboukhatwa, MA; Undieh, AS | 1 |
| Arias, HR; Feuerbach, D; Jozwiak, K; Russell, M; Targowska-Duda, KM | 1 |
| Holsboer, F; Perisic, T; Rein, T; Yu, S; Zimmermann, N; Zschocke, J | 1 |
| Amsterdam, JD; McHenry, LB | 1 |
| Araki, H; Hato-Yamada, N; Su, J; Yoshimura, H | 1 |
| Cho, HY; Kim, JE; Kim, YH; Lee, BJ; Lee, CH; Lee, JG; Park, SW; Seo, MK; Seol, W | 1 |
| Araki, H; Miyawaki, K; Yoshimura, H | 1 |
| Ahmed, HI; El-Denshary, EE; Nadeem, RI | 1 |
| Abi-Jaoude, E; Healy, D; Jureidini, J; Le Noury, J; Nardo, JM; Raven, M; Tufanaru, C | 3 |
| Linden, DE | 1 |
| Sasich, LD | 1 |
| Birkenhager, TK | 1 |
| Bagmetova, VV; Chernysheva, YV; Ozerov, AA; Tyurenkov, IN | 1 |
| Harada, S; Matsuura, W; Tokuyama, S | 1 |
| Freitas, RM; Moreno, LCGEAI; Rolim, HML; Santos-Magalhães, NS | 1 |
| Cipriani, A; Coghill, D; Cohen, D; Cuijpers, P; Del Giovane, C; Hazell, P; Hetrick, SE; Leucht, S; Liu, L; Liu, Y; Michael, KD; Pu, J; Qin, B; Ravindran, AV; Whittington, C; Xie, P; Yang, L; Zhang, Y; Zhou, X | 1 |
| Mulder, R; Rucklidge, JJ; Toop, L | 1 |
| Barbui, C; Bighelli, I; Breilmann, J; Castellazzi, M; Cipriani, A; Davies, SJ; Furukawa, TA; Girlanda, F; Guaiana, G; Koesters, M | 1 |
| Cao, Q; Rao, Y; Yang, R; Zhao, J | 1 |
17 review(s) available for imipramine and paroxetine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Potential pharmacological strategies targeting the Niemann-Pick C1 receptor and Ebola virus glycoprotein interaction.
Topics: Antibodies; Ebolavirus; Glycoproteins; Hemorrhagic Fever, Ebola; Humans; Molecular Docking Simulation; Niemann-Pick C1 Protein; Protein Binding; Small Molecule Libraries; Virus Internalization | 2021 |
Melancholic/endogenous depression and response to somatic treatment and placebo.
Topics: Antidepressive Agents; Depressive Disorder; Double-Blind Method; Fluoxetine; Humans; Imipramine; Oximes; Paroxetine; Piperidines; Placebos; Prospective Studies; Psychiatric Status Rating Scales; Treatment Outcome | 1992 |
Paroxetine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in depressive illness.
Topics: Amitriptyline; Animals; Antidepressive Agents; Clomipramine; Depressive Disorder; Drug Evaluation; Drug Tolerance; Humans; Imipramine; Paroxetine; Piperidines; Serotonin Antagonists | 1991 |
Depression and selective serotonin reuptake inhibitors.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depression; Fluoxetine; Humans; Imipramine; Meta-Analysis as Topic; Middle Aged; Multicenter Studies as Topic; Paroxetine; Piperidines; Serotonin Antagonists | 1990 |
Therapeutic effects of serotonin uptake inhibitors in depression.
Topics: 5-Hydroxytryptophan; Alanine; Citalopram; Depressive Disorder; Fluoxetine; Fluvoxamine; Humans; Imipramine; Oximes; Paroxetine; Piperidines; Propylamines; Serotonin; Serotonin Antagonists; Trazodone; Zimeldine | 1986 |
Studies on the serotonin transporter in platelets.
Topics: Animals; Antidepressive Agents, Tricyclic; Binding Sites; Blood Platelets; Carrier Proteins; Humans; Imipramine; Paroxetine; Piperidines; Serotonin Antagonists | 1988 |
Comparison of the tolerability of bupropion, fluoxetine, imipramine, nefazodone, paroxetine, sertraline, and venlafaxine.
Topics: 1-Naphthylamine; Antidepressive Agents; Bupropion; Clinical Trials as Topic; Cyclohexanols; Depressive Disorder; Drug Design; Drug Tolerance; Drugs, Investigational; Fluoxetine; Humans; Imipramine; Paroxetine; Piperazines; Selective Serotonin Reuptake Inhibitors; Sertraline; Triazoles; Venlafaxine Hydrochloride | 1995 |
Guidelines for the long-term treatment of depression.
Topics: Adult; Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Combined Modality Therapy; Depressive Disorder; Drug Administration Schedule; Female; Fluoxetine; Follow-Up Studies; Humans; Imipramine; Middle Aged; Paroxetine; Placebos; Psychotherapy; Recurrence; Time Factors; Treatment Outcome | 1994 |
Management of recurrent depression.
Topics: 1-Naphthylamine; Antidepressive Agents; Chronic Disease; Combined Modality Therapy; Depressive Disorder; Drug Administration Schedule; Fluoxetine; Humans; Imipramine; Paroxetine; Psychotherapy; Recurrence; Sertraline | 1993 |
Treating generalized anxiety disorder.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Anxiety Disorders; Benzodiazepines; Buspirone; Clinical Trials as Topic; Cognitive Behavioral Therapy; Cyclohexanols; Humans; Imipramine; Paroxetine; Psychotherapy; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; United States; Venlafaxine Hydrochloride | 2003 |
Cost-effectiveness of psychological and pharmacological interventions for generalized anxiety disorder and panic disorder.
Topics: Antidepressive Agents, Tricyclic; Anxiety Disorders; Australia; Cost-Benefit Analysis; Cyclohexanols; Disability Evaluation; Humans; Imipramine; Mental Health Services; Panic Disorder; Paroxetine; Psychotherapy; Selective Serotonin Reuptake Inhibitors; Time Factors; Venlafaxine Hydrochloride | 2004 |
The efficacy of antidepressants for generalized anxiety disorder: a systematic review and meta-analysis.
Topics: Antidepressive Agents; Anxiety Disorders; Cyclohexanols; Female; Humans; Imipramine; Male; Paroxetine; Randomized Controlled Trials as Topic; Treatment Outcome; Venlafaxine Hydrochloride | 2005 |
[Review of pharmacological efficacies and side effects of antidepressants].
Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Fluvoxamine; Humans; Imipramine; Maprotiline; Paroxetine; Sulpiride; Trazodone | 2007 |
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.
Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Confounding Factors, Epidemiologic; Depressive Disorder, Major; Desipramine; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Evidence-Based Medicine; Fluoxetine; Humans; Imipramine; Mianserin; Mirtazapine; Nortriptyline; Paroxetine; Piperazines; Randomized Controlled Trials as Topic; Research Design; Sertraline; Treatment Outcome; Triazoles; Venlafaxine Hydrochloride | 2016 |
Benzodiazepines versus placebo for panic disorder in adults.
Topics: Adult; Aged; Agoraphobia; Benzodiazepines; Buspirone; Humans; Imipramine; Middle Aged; Numbers Needed To Treat; Panic Disorder; Paroxetine; Patient Dropouts; Placebos; Propranolol; Randomized Controlled Trials as Topic; Remission Induction; Young Adult | 2019 |
Efficacy and tolerability of antidepressant drugs in treatment of depression in children and adolescents: a network meta-analysis.
Topics: Adolescent; Amitriptyline; Antidepressive Agents; Child; Depression; Depressive Disorder, Major; Duloxetine Hydrochloride; Escitalopram; Fluoxetine; Humans; Imipramine; Network Meta-Analysis; Paroxetine; Sertraline; Venlafaxine Hydrochloride | 2022 |
43 trial(s) available for imipramine and paroxetine
| Article | Year |
|---|---|
Plasma beta-endorphin is not affected by treatment with imipramine or paroxetine in patients with diabetic neuropathy symptoms.
Topics: Adult; Aged; Antidepressive Agents; beta-Endorphin; Diabetic Neuropathies; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Paroxetine; Piperidines | 1992 |
Sociotropy and autonomy: relationship to antidepressant drug treatment response and endogenous-nonendogenous dichotomy.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Imipramine; Individuality; Internal-External Control; Interpersonal Relations; Male; Oximes; Paroxetine; Piperidines; Serotonin Antagonists | 1992 |
Melancholic/endogenous depression and response to somatic treatment and placebo.
Topics: Antidepressive Agents; Depressive Disorder; Double-Blind Method; Fluoxetine; Humans; Imipramine; Oximes; Paroxetine; Piperidines; Placebos; Prospective Studies; Psychiatric Status Rating Scales; Treatment Outcome | 1992 |
A double-blind comparison of paroxetine, imipramine and placebo in depressed outpatients.
Topics: Adult; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Paroxetine; Psychiatric Status Rating Scales | 1992 |
Paroxetine and imipramine in the treatment of depressive patients in psychiatric practice.
Topics: Adolescent; Aged; Ambulatory Care; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Imipramine; Long-Term Care; Male; Middle Aged; Paroxetine; Personality Inventory | 1992 |
A 6-week, double-blind trial of paroxetine, imipramine, and placebo in depressed outpatients.
Topics: Adult; Ambulatory Care; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Neurotransmitter Uptake Inhibitors; Paroxetine; Patient Dropouts; Piperidines; Placebos; Psychiatric Status Rating Scales | 1992 |
Paroxetine in the treatment of depression: a comparison with imipramine and placebo.
Topics: Adolescent; Adult; Ambulatory Care; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Neurotransmitter Uptake Inhibitors; Paroxetine; Patient Dropouts; Piperidines; Placebos; Psychiatric Status Rating Scales | 1992 |
A double-blind comparison of paroxetine, imipramine, and placebo in major depression.
Topics: Adult; Ambulatory Care; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Neurotransmitter Uptake Inhibitors; Paroxetine; Patient Dropouts; Piperidines; Placebos; Prospective Studies; Psychiatric Status Rating Scales | 1992 |
Paroxetine in major depression: a double-blind trial with imipramine and placebo.
Topics: Adult; Antidepressive Agents; Anxiety Disorders; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Neurotransmitter Uptake Inhibitors; Paroxetine; Piperidines; Placebos; Prospective Studies | 1992 |
Novel selective serotonin reuptake inhibitors, Part II.
Topics: Adult; Aged; Ambulatory Care; Depressive Disorder; Humans; Imipramine; Neurotransmitter Uptake Inhibitors; Paroxetine; Piperidines; Placebos; Recurrence; Serotonin; Serotonin Antagonists | 1992 |
Paroxetine and imipramine treatment of depressive patients in a controlled multicentre study with plasma amino acid measurements.
Topics: Amino Acids; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Imipramine; Male; Paroxetine; Piperidines; Psychiatric Status Rating Scales; Serotonin Antagonists | 1991 |
A comparison of paroxetine, imipramine and placebo in depressed out-patients.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Paroxetine; Personality Tests; Piperidines; Serotonin Antagonists | 1991 |
A placebo- and imipramine-controlled study of paroxetine.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Paroxetine; Piperidines; Psychiatric Status Rating Scales | 1990 |
The selective serotonin reuptake inhibitor paroxetine is effective in the treatment of diabetic neuropathy symptoms.
Topics: Depression; Desipramine; Diabetic Neuropathies; Humans; Imipramine; Nervous System; Osmolar Concentration; Paroxetine; Piperidines; Serotonin Antagonists; Time Factors | 1990 |
Paroxetine in the treatment of depression: a comparison with imipramine and placebo.
Topics: Antidepressive Agents; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Imipramine; Paroxetine; Piperidines; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Serotonin Antagonists | 1989 |
The short- and long-term efficacy of paroxetine HCl: A. Data from a 6-week double-blind parallel design trial vs. imipramine and placebo.
Topics: Antidepressive Agents; Depressive Disorder; Double-Blind Method; Humans; Imipramine; Paroxetine; Piperidines; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic | 1989 |
The short- and long-term efficacy of paroxetine HCl: B. Data from a double-blind crossover study and from a year-long term trial vs. imipramine and placebo.
Topics: Antidepressive Agents; Depressive Disorder; Double-Blind Method; Humans; Imipramine; Paroxetine; Piperidines; Randomized Controlled Trials as Topic | 1989 |
The predictive value of the dexamethasone suppression test. A placebo-controlled study.
Topics: Adult; Ambulatory Care; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Dexamethasone; Double-Blind Method; Female; Humans; Hydrocortisone; Imipramine; Male; Middle Aged; Paroxetine; Piperidines; Placebos; Predictive Value of Tests; Psychiatric Status Rating Scales | 1989 |
Fluoxetine in panic disorder: pharmacologic and tritiated platelet imipramine and paroxetine binding study.
Topics: Adolescent; Adult; Agoraphobia; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Panic Disorder; Paroxetine; Patient Dropouts; Prospective Studies; Psychiatric Status Rating Scales | 1995 |
Childhood psychopathology retrospectively assessed among adults with early onset major depression.
Topics: 1-Naphthylamine; Adolescent; Adult; Anxiety Disorders; Child; Child Behavior Disorders; Comorbidity; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Imipramine; Male; Mental Disorders; Middle Aged; Paroxetine; Personality Development; Phobic Disorders; Recurrence; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Sertraline | 1994 |
A 12-week double-blind multi-centre study of paroxetine and imipramine in hospitalized depressed patients.
Topics: Adult; Aged; Depressive Disorder; Double-Blind Method; Female; Hospitalization; Humans; Imipramine; Male; Middle Aged; Paroxetine; Psychiatric Status Rating Scales | 1994 |
A double-blind comparison of paroxetine with imipramine in the long-term treatment of depression.
Topics: Adult; Aged; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Imipramine; Long-Term Care; Male; Middle Aged; Paroxetine; Personality Inventory | 1993 |
A study comparing paroxetine placebo and imipramine in depressed patients.
Topics: Adolescent; Adult; Aged; Anxiety Disorders; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Paroxetine; Personality Inventory | 1993 |
Direct cost of depression: analysis of treatment costs of paroxetine versus Imipramine in Canada.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Canada; Computer Simulation; Cost-Benefit Analysis; Decision Trees; Depressive Disorder; Direct Service Costs; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Imipramine; Male; Middle Aged; Paroxetine; Patient Readmission; Treatment Outcome | 1995 |
Paroxetine in the treatment of Chinese patients with depressive episode: a double-blind randomized comparison with imipramine.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depression; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Paroxetine; Selective Serotonin Reuptake Inhibitors | 1996 |
Relapse prevention by means of paroxetine in ECT-treated patients with major depression: a comparison with imipramine and placebo in medium-term continuation therapy.
Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Denmark; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electroconvulsive Therapy; Female; Follow-Up Studies; Humans; Imipramine; Male; Middle Aged; Paroxetine; Personality Inventory; Recurrence; Treatment Outcome | 1996 |
Economic evaluation of paroxetine and imipramine in depressed outpatients.
Topics: Adolescent; Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Child; Depressive Disorder; Female; Humans; Imipramine; Male; Middle Aged; Outpatients; Paroxetine; Retrospective Studies; Treatment Outcome | 1997 |
Paroxetine efficacy in the treatment of generalized anxiety disorder.
Topics: Adolescent; Adult; Analysis of Variance; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Benzodiazepines; Chi-Square Distribution; Female; Humans; Imipramine; Male; Middle Aged; Nordazepam; Paroxetine; Treatment Outcome | 1997 |
Antidepressant response follows an exponential decay curve: replication and extension.
Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depressive Disorder; Fluoxetine; Humans; Imipramine; Models, Statistical; Paroxetine; Personality Inventory; Psychometrics; Pyridazines; Treatment Outcome | 1997 |
The impact of treatment resistance on depressive relapse following electroconvulsive therapy.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Combined Modality Therapy; Depressive Disorder; Electroconvulsive Therapy; Humans; Imipramine; Paroxetine; Recurrence; Treatment Outcome | 1997 |
Randomized, placebo-controlled trial of paroxetine versus imipramine in depressed HIV-positive outpatients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Ambulatory Care; Comorbidity; Depressive Disorder; Female; HIV Infections; Humans; Imipramine; Male; Paroxetine; Patient Dropouts; Placebos; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 1998 |
A double-blind comparison of the efficacy and safely of paroxetine and imipramine in the treatment of depression with dementia.
Topics: Aged; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Dementia; Depressive Disorder; Double-Blind Method; Drug Tolerance; Female; Humans; Imipramine; Male; Paroxetine; Prospective Studies; Time Factors; Treatment Outcome | 1998 |
The effect of clinical outcome on platelet G proteins of major depressed patients.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Blood Platelets; Blotting, Western; Clomipramine; Depressive Disorder; Female; GTP-Binding Proteins; Humans; Imipramine; Male; Middle Aged; Paroxetine; Psychiatric Status Rating Scales; Signal Transduction; Treatment Outcome | 1998 |
Pharmacologic effect of imipramine, paroxetine, and sertraline on 35% carbon dioxide hypersensitivity in panic patients: a double-blind, random, placebo-controlled study.
Topics: Adult; Antidepressive Agents, Tricyclic; Anxiety; Carbon Dioxide; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Multivariate Analysis; Panic Disorder; Paroxetine; Placebos; Selective Serotonin Reuptake Inhibitors; Sertraline | 1997 |
A prospective naturalistic study of 326 panic-agoraphobic patients treated with antidepressants.
Topics: Adult; Aged; Agoraphobia; Antidepressive Agents; Clomipramine; Demography; Female; Humans; Imipramine; Italy; Longitudinal Studies; Male; Middle Aged; Panic Disorder; Paroxetine; Patient Dropouts; Probability; Prospective Studies; Time Factors; Treatment Outcome | 2000 |
Double-blind, placebo-controlled comparison of imipramine and paroxetine in the treatment of bipolar depression.
Topics: Adult; Aged; Ambulatory Care; Anticonvulsants; Antidepressive Agents, Tricyclic; Bipolar Disorder; Carbamazepine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Imipramine; Lithium; Male; Middle Aged; Paroxetine; Placebos; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Valproic Acid | 2001 |
Efficacy of paroxetine in the treatment of adolescent major depression: a randomized, controlled trial.
Topics: Adolescent; Analysis of Variance; Antidepressive Agents, Tricyclic; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Imipramine; Least-Squares Analysis; Male; Paroxetine; Selective Serotonin Reuptake Inhibitors | 2001 |
Platelet serotonergic predictors of clinical improvement in obsessive compulsive disorder.
Topics: Adolescent; Adult; Binding Sites; Biomarkers; Blood Platelets; Carrier Proteins; Cell Membrane; Child; Diet; Female; France; Humans; Imipramine; Inositol Phosphates; Iodine Isotopes; Lysergic Acid Diethylamide; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Obsessive-Compulsive Disorder; Paroxetine; Psychiatric Status Rating Scales; Radiochemistry; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Treatment Outcome; Tritium; Tryptophan | 2004 |
Cost-efficacy of individual and combined treatments for panic disorder.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cognitive Behavioral Therapy; Combined Modality Therapy; Cost-Benefit Analysis; Health Care Costs; Humans; Imipramine; Panic Disorder; Paroxetine; Treatment Outcome | 2007 |
The paroxetine 352 bipolar trial: A study in medical ghostwriting.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bipolar Disorder; Conflict of Interest; Double-Blind Method; Humans; Imipramine; Paroxetine; Scientific Misconduct; Treatment Outcome | 2012 |
Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Antidepressive Agents, Second-Generation; Data Interpretation, Statistical; Depressive Disorder, Major; Double-Blind Method; Evidence-Based Medicine; Humans; Imipramine; Paroxetine; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Treatment Outcome | 2015 |
Restoring Study 329: Paroxetine neither effective nor safe for adolescents.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Imipramine; Male; Outcome Assessment, Health Care; Paroxetine; Selective Serotonin Reuptake Inhibitors; Treatment Failure | 2016 |
Study 329 continuation phase: Safety and efficacy of paroxetine and imipramine in extended treatment of adolescent major depression.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Child; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Imipramine; Male; Paroxetine; Psychiatric Status Rating Scales; Recurrence | 2016 |
142 other study(ies) available for imipramine and paroxetine
| Article | Year |
|---|---|
Pyrroloisoquinoline antidepressants. 3. A focus on serotonin.
Topics: Animals; Antidepressive Agents; Biological Assay; Biological Transport; Dose-Response Relationship, Drug; Isoquinolines; Mice; Pyrroles; Rats; Serotonin; Structure-Activity Relationship | 1990 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
An antidepressant that extends lifespan in adult Caenorhabditis elegans.
Topics: Aging; Animals; Antidepressive Agents; Caenorhabditis elegans; Caloric Restriction; Humans; Longevity; Methiothepin; Mianserin; Octopamine; Receptors, Biogenic Amine; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Starvation | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells).
Topics: Adrenergic beta-Antagonists; Amines; Ammonium Chloride; Antidepressive Agents, Tricyclic; Atorvastatin; Cell Line, Transformed; Diuretics; Hepatocytes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imipramine; Lysosomes; Monensin; Nigericin; Propranolol; Pyrroles | 2013 |
Which metabolites circulate?
Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Discovery of SMP-304, a novel benzylpiperidine derivative with serotonin transporter inhibitory activity and 5-HT
Topics: Animals; Antidepressive Agents; Cytochrome P-450 CYP2D6 Inhibitors; Dioxanes; Drug Partial Agonism; Humans; Male; Piperidines; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Serotonin Plasma Membrane Transport Proteins | 2017 |
Discovery of potent ebola entry inhibitors with (3S,4aS,8aS)-2-(3-amino-2-hydroxypropyl) decahydroisoquinoline-3-carboxamide scaffold.
Topics: Antiviral Agents; Ebolavirus; Hemorrhagic Fever, Ebola; HIV Fusion Inhibitors; Humans; Molecular Docking Simulation; Virus Internalization | 2022 |
Serotonergic aspects of the response of human platelets to immune-adjuvant muramyl dipeptide.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adenosine Diphosphate; Adjuvants, Immunologic; Blood Platelets; Carrier Proteins; Humans; Imipramine; Ketanserin; Lysergic Acid Diethylamide; Paroxetine; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1992 |
Chloroamphetamine did not prevent the effects of chronic antidepressants on 5-hydroxytryptamine inhibition of forskolin-stimulated adenylate cyclase in rat hippocampus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Antidepressive Agents; Binding Sites; Cerebral Cortex; Chlorides; Colforsin; Hippocampus; Imipramine; Lithium; Lithium Chloride; Male; p-Chloroamphetamine; Paroxetine; Piperidines; Rats; Serotonin; Synapses; Tetrahydronaphthalenes | 1991 |
[3H]citalopram binding to brain and platelet membranes of human and rat.
Topics: Animals; Binding Sites; Blood Platelets; Brain; Carrier Proteins; Cell Membrane; Citalopram; Humans; Imipramine; Kinetics; Neurons; Paroxetine; Piperidines; Rats; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Temperature; Thermodynamics | 1991 |
Affinity modulation of [3H]imipramine, [3H]paroxetine and [3H]citalopram binding to the 5-HT transporter from brain and platelets.
Topics: Animals; Blood Platelets; Brain; Carrier Proteins; Cell Membrane; Citalopram; Half-Life; Humans; Imipramine; In Vitro Techniques; Membrane Proteins; Paroxetine; Piperidines; Rats; Serotonin Plasma Membrane Transport Proteins | 1991 |
Evidence for the existence of serotonin uptake inhibitor-like substances in human cerebrospinal fluid.
Topics: Animals; Binding Sites; Brain; Haplorhini; Humans; Imipramine; Paroxetine; Piperidines; Serotonin; Serotonin Antagonists; Synaptosomes | 1991 |
Platelet 3H-paroxetine binding to the serotonin transporter is insensitive to changes in central serotonergic innervation in the rat.
Topics: 5,7-Dihydroxytryptamine; Animals; Brain; Depressive Disorder; Imipramine; Male; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists | 1991 |
Platelet 3H-imipramine and 3H-paroxetine binding during treatment with psychoactive drugs.
Topics: Adult; Aged; Aged, 80 and over; Blood Platelets; Female; Humans; Imipramine; Male; Mental Disorders; Middle Aged; Paroxetine; Piperidines; Psychotropic Drugs; Radioligand Assay; Serotonin Antagonists | 1991 |
Presynaptic and postsynaptic modifications of the serotonin system by long-term administration of antidepressant treatments. An in vivo electrophysiologic study in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Electric Stimulation; Electrophysiology; Hippocampus; Imipramine; Male; Neurons; Paroxetine; Piperidines; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synapses; Tetrahydronaphthalenes | 1991 |
Antidepressant binding sites in brain: autoradiographic comparison of [3H]paroxetine and [3H]imipramine localization and relationship to serotonin transporter.
Topics: Animals; Antidepressive Agents; Autoradiography; Binding Sites; Brain; Imipramine; In Vitro Techniques; Kinetics; Male; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin | 1990 |
Regional distribution of the serotonin transport complex in human brain, identified with 3H-paroxetine, 3H-citalopram and 3H-imipramine.
Topics: Adolescent; Adult; Aged; Binding, Competitive; Biological Transport; Brain; Citalopram; Female; Humans; Imipramine; Kinetics; Male; Membranes; Middle Aged; Organ Specificity; Paroxetine; Piperidines; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1990 |
[3H] sertraline binding to rat brain membranes.
Topics: 1-Naphthylamine; Animals; Brain; Fenclonine; Fluoxetine; Imipramine; In Vitro Techniques; Male; Membranes; Naphthalenes; Paroxetine; Piperidines; Rats; Receptors, Serotonin; Serotonin Antagonists; Sertraline | 1990 |
Inhibition of MAO activity, 3H-imipramine binding, 3H-paroxetine binding and 3H-5-HT uptake by human cerebrospinal fluid.
Topics: Animals; Binding, Competitive; Brain; Cerebral Cortex; Cerebrospinal Fluid; Humans; Imipramine; Kinetics; Macaca mulatta; Membranes; Mitochondria; Monoamine Oxidase Inhibitors; Paroxetine; Piperidines; Receptors, Drug; Serotonin | 1990 |
Why some depressed patients may have low platelet 3H-imipramine binding.
Topics: Antidepressive Agents; Blood Platelets; Carrier Proteins; Cell Membrane; Clomipramine; Depressive Disorder; Humans; Imipramine; Paroxetine; Piperidines; Receptors, Drug; Receptors, Neurotransmitter; Serotonin Antagonists | 1990 |
Age-related changes in rat serotonergic and adrenergic systems and in receptor responsiveness to subchronic desipramine treatment.
Topics: Aging; Animals; Brain; Clonidine; Desipramine; Dihydroalprenolol; Hydroxyindoleacetic Acid; Imipramine; Ketanserin; Kinetics; Male; Paroxetine; Piperidines; Prazosin; Proteins; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Serotonin; Serotonin; Time Factors | 1988 |
Differences in the temperature dependence of drug interaction with the noradrenaline and serotonin transporters.
Topics: Animals; Biogenic Monoamines; Blood Platelets; Humans; Imipramine; In Vitro Techniques; Male; Mazindol; Norepinephrine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Salivary Glands; Serotonin; Serotonin Antagonists; Temperature | 1989 |
Light-dark differences in [3H]-paroxetine binding to rabbit platelet membranes.
Topics: Animals; Blood Platelets; Cell Membrane; Circadian Rhythm; Darkness; Imipramine; In Vitro Techniques; Light; Male; Paroxetine; Piperidines; Rabbits; Serotonin Antagonists | 1989 |
A common binding site for tricyclic and nontricyclic 5-hydroxytryptamine uptake inhibitors at the substrate recognition site of the neuronal sodium-dependent 5-hydroxytryptamine transporter.
Topics: Animals; Antidepressive Agents, Tricyclic; Binding Sites; Binding, Competitive; Biological Transport; Cerebral Cortex; Citalopram; Dose-Response Relationship, Drug; Ethylmaleimide; Fluoxetine; Imipramine; Male; Neurons; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sodium | 1989 |
Interaction between tricyclic and nontricyclic 5-hydroxytryptamine uptake inhibitors and the presynaptic 5-hydroxytryptamine inhibitory autoreceptors in the rat hypothalamus.
Topics: 5-Methoxytryptamine; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Citalopram; Electric Stimulation; Fenclonine; Hypothalamus; Imipramine; Lysergic Acid Diethylamide; Male; Methiothepin; Neurotransmitter Agents; Pargyline; Paroxetine; Piperidines; Propylamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin | 1985 |
The activity of 25 paroxetine/femoxetine structure variants in various reactions, assumed to be important for the effect of antidepressants.
Topics: Animals; Blood Platelets; Humans; Imipramine; In Vitro Techniques; Neurons; Paroxetine; Piperidines; Rats; Serotonin; Structure-Activity Relationship; Synaptosomes | 1987 |
Antidepressive drugs can change the affinity of [3H]imipramine and [3H]paroxetine binding to platelet and neuronal membranes.
Topics: Animals; Antidepressive Agents; Binding Sites; Binding, Competitive; Blood Platelets; Brain; Cell Membrane; Citalopram; Imipramine; In Vitro Techniques; Kinetics; Paroxetine; Piperidines; Propylamines; Rats; Serotonin; Serotonin Antagonists; Synaptic Membranes | 1985 |
Parkinson's disease: decreased density of 3H-imipramine and 3H-paroxetine binding sites in putamen.
Topics: Aged; Binding Sites; Humans; Imipramine; Middle Aged; Parkinson Disease; Paroxetine; Piperidines; Putamen; Tritium | 1986 |
High affinity binding of 3H-paroxetine and 3H-imipramine to rat neuronal membranes.
Topics: Animals; Binding Sites; Blood Platelets; Brain; Female; Imipramine; In Vitro Techniques; Membranes; Paroxetine; Piperidines; Rats; Rats, Inbred Strains | 1986 |
High- and low-affinity binding of [3H]imipramine in rat hypothalamus.
Topics: Amitriptyline; Animals; Citalopram; Clomipramine; Cyclopropanes; Hypothalamus; Imipramine; Kinetics; Male; Milnacipran; Paroxetine; Piperidines; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Sodium | 1986 |
Temperature dependence of drug interaction with the platelet 5-hydroxytryptamine transporter: a clue to the imipramine selectivity paradox.
Topics: Biological Transport, Active; Blood Platelets; Humans; Imipramine; Kinetics; Paroxetine; Piperidines; Receptors, Serotonin; Temperature | 1987 |
Chlorimipramine--but not imipramine--rapidly reduces imipramine--but not paroxetine--binding in human platelets.
Topics: Blood Platelets; Clomipramine; Humans; Imipramine; Iodine; Paroxetine; Piperidines; Serotonin; Tritium | 1986 |
Cardiovascular effects of paroxetine, a newly developed antidepressant, in anesthetized dogs in comparison with those of imipramine, amitriptyline and clomipramine.
Topics: Amitriptyline; Anesthesia; Animals; Antidepressive Agents; Atrioventricular Node; Blood Pressure; Clomipramine; Dogs; Electrocardiography; Female; Heart Conduction System; Heart Rate; Hemodynamics; Imipramine; Male; Paroxetine; Piperidines; Respiration | 1987 |
Characterization of [3H]paroxetine binding in rat brain.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Cerebral Cortex; Citalopram; Fluoxetine; Imipramine; Male; Paroxetine; Peptide Hydrolases; Piperidines; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tritium | 1988 |
Dissociation kinetics of [3H]paroxetine binding to rat brain consistent with a single-site model of the antidepressant binding/5-hydroxytryptamine uptake site.
Topics: Animals; Brain; Cell Membrane; Citalopram; Clomipramine; Imipramine; Kinetics; Male; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Zimeldine | 1988 |
Autoradiography of antidepressant binding sites in the human brain: localization using [3H]imipramine and [3H]paroxetine.
Topics: Aged; Aged, 80 and over; Antidepressive Agents; Autoradiography; Brain; Child; Female; Humans; Imipramine; Male; Middle Aged; Paroxetine; Piperidines; Receptors, Serotonin; Spinal Cord | 1988 |
Measuring the serotonin uptake site using [3H]paroxetine--a new serotonin uptake inhibitor.
Topics: Animals; Cerebral Cortex; Electroconvulsive Therapy; Imipramine; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Obese; Paroxetine; Piperidines; Receptors, Serotonin; Tritium | 1988 |
Specific binding sites for cyclic antidepressants.
Topics: Animals; Binding Sites; Carrier Proteins; Humans; Imipramine; Paroxetine; Piperidines; Receptors, Drug; Receptors, Neurotransmitter; Serotonin; Temperature | 1985 |
Pitfalls in demonstrating an endogenous ligand of imipramine recognition sites.
Topics: Animals; Binding Sites; Brain Chemistry; Chromatography, High Pressure Liquid; Imipramine; Ligands; Osmolar Concentration; Paroxetine; Piperidines; Rats; Receptors, Cell Surface; Serotonin; Serotonin Antagonists | 1987 |
Association of [3H]-imipramine and [3H]-paroxetine binding with the 5HT transporter in brain and platelets: relevance to studies in depression.
Topics: Animals; Antidepressive Agents; Blood Platelets; Brain Chemistry; Carrier Proteins; Depressive Disorder; Female; Humans; Imipramine; Male; Paroxetine; Piperidines; Rabbits; Rats; Receptors, Drug; Receptors, Neurotransmitter; Receptors, Serotonin; Serotonin | 1987 |
Size determination of binding polymers for [3H]imipramine and [3H]paroxetine in human platelet membranes.
Topics: Blood Platelets; Carrier Proteins; Cell Membrane; Electrons; Humans; Imipramine; In Vitro Techniques; Membrane Proteins; Molecular Weight; Paroxetine; Piperidines; Protein Binding; Receptors, Drug; Receptors, Neurotransmitter; Serotonin Antagonists | 1984 |
Imipramine binding site. Temperature dependence of the binding of 3H-labeled imipramine and 3H-labeled paroxetine to human platelet membrane.
Topics: Binding Sites; Blood Platelets; Cell Membrane; Humans; Imipramine; Kinetics; Mathematics; Paroxetine; Piperidines; Temperature | 1984 |
High affinity binding of [3H]paroxetine and [3H]imipramine to human platelet membranes.
Topics: Antidepressive Agents, Tricyclic; Blood Platelets; Cell Membrane; Humans; Imipramine; Kinetics; Paroxetine; Piperidines; Receptors, Serotonin; Serotonin Antagonists | 1983 |
Differences in brain 5-HT transporter dissociation rates among animal species.
Topics: Adrenergic Uptake Inhibitors; Animals; Biological Transport, Active; Brain Chemistry; Citalopram; Humans; Imipramine; Mice; Paroxetine; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Swine | 1995 |
Economics of treatment of depression.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cost-Benefit Analysis; Depressive Disorder; Humans; Imipramine; Paroxetine | 1995 |
Reduction of suicidal thoughts with paroxetine in comparison with reference antidepressants and placebo.
Topics: Antidepressive Agents; Female; Humans; Imipramine; Male; Paroxetine; Psychiatric Status Rating Scales; Suicide; Suicide, Attempted; Time Factors | 1995 |
Serotonin uptake inhibitors modulate intracellular Ca2+ mobilization in platelets.
Topics: 1-Naphthylamine; Blood Platelets; Calcium; Calmodulin; Cells, Cultured; Fluoxetine; Humans; Imipramine; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline | 1995 |
Economics of treatment of depression.
Topics: Bias; Cost-Benefit Analysis; Depressive Disorder; Humans; Imipramine; Paroxetine; Patient Dropouts | 1995 |
Different effects of antidepressants on dissociation of 3H-imipramine from solubilized binding sites of rat brain.
Topics: Animals; Antidepressive Agents; Binding Sites; Brain; Carrier Proteins; Citalopram; Dose-Response Relationship, Drug; Imipramine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Wistar; Serotonin; Serotonin Plasma Membrane Transport Proteins | 1994 |
Cost-effectiveness of antidepressants.
Topics: Ambulatory Care; Cost-Benefit Analysis; Depressive Disorder; Humans; Imipramine; Paroxetine; Patient Dropouts; Recurrence | 1994 |
Platelet 5-HT uptake sites in depression: three concurrent measures using [3H] imipramine and [3H] paroxetine.
Topics: Adult; Biomarkers; Blood Platelets; Cell Membrane; Citalopram; Depressive Disorder; Desipramine; Female; Humans; Imipramine; In Vitro Techniques; Male; Middle Aged; Paroxetine; Receptors, Serotonin; Sodium | 1993 |
Solubilization and characterization of [3H]imipramine and [3H]paroxetine binding sites from calf striatum.
Topics: Animals; Carrier Proteins; Cattle; Corpus Striatum; Imipramine; Membrane Glycoproteins; Membrane Transport Proteins; Membranes; Nerve Tissue Proteins; Paroxetine; Receptors, Drug; Serotonin; Serotonin Plasma Membrane Transport Proteins; Solubility; Tritium | 1994 |
What price depression? The cost of depression and the cost-effectiveness of pharmacological treatment.
Topics: Antidepressive Agents; Cost of Illness; Cost-Benefit Analysis; Depressive Disorder; Humans; Imipramine; Models, Economic; Paroxetine; Randomized Controlled Trials as Topic; Treatment Outcome; United Kingdom | 1994 |
Further studies on platelet serotonin transporter binding in depression.
Topics: Antidepressive Agents; Blood Proteins; Carrier Proteins; Depressive Disorder; Female; Glycoproteins; Humans; Imipramine; Ligands; Male; Middle Aged; Paroxetine; Radioligand Assay; Receptors, Drug; Serotonin; Serotonin Plasma Membrane Transport Proteins | 1994 |
Automated determination of paroxetine and its main metabolite by column switching and on-line high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Humans; Imipramine; Mixed Function Oxygenases; Paroxetine; Piperidines; Sensitivity and Specificity | 1994 |
Platelet 3H-paroxetine binding in control subjects and depressed patients: relationship to serotonin uptake and age.
Topics: Adult; Age Factors; Binding Sites; Blood Platelets; Depressive Disorder; Desipramine; Female; Fluoxetine; Humans; Imipramine; Infant; Male; Paroxetine; Serotonin | 1994 |
Influence of antidepressants on whole gut and orocaecal transit times in health and irritable bowel syndrome.
Topics: Adult; Colonic Diseases, Functional; Female; Gastrointestinal Transit; Humans; Imipramine; Male; Middle Aged; Paroxetine | 1994 |
Comparative study of platelet 3H-paroxetine and 3H-imipramine binding in panic disorder patients and healthy controls.
Topics: Adult; Binding Sites; Biological Transport; Blood Platelets; Female; Humans; Imipramine; Male; Panic Disorder; Paroxetine; Serotonin | 1994 |
Further evidence for the existence of endogenous serotonin uptake inhibitors and their purification by calmodulin affinity chromatography.
Topics: Adult; Antibodies; Biological Factors; Brain; Calmodulin; Chromatography, Agarose; Chromatography, Gel; Depressive Disorder; Female; Humans; Imipramine; Male; Paroxetine; Radioimmunoassay; Selective Serotonin Reuptake Inhibitors; Serotonin; Structure-Activity Relationship | 1993 |
Stress and antidepressant effects on hippocampal and cortical 5-HT1A and 5-HT2 receptors and transport sites for serotonin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Autoradiography; Carrier Proteins; Cerebral Cortex; Corticosterone; Hippocampus; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Restraint, Physical; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stress, Psychological; Thiazepines | 1993 |
Central serotonergic uptake mechanisms in hypertensive rats: effects of clonidine and centhaquin.
Topics: Animals; Binding, Competitive; Blood Pressure; Brain Chemistry; Brain Stem; Cell Membrane; Cerebral Cortex; Clonidine; Heart Rate; Hypertension; Imipramine; Neurons; Paroxetine; Piperazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Serotonin; Serotonin | 1993 |
Aging and 3H-paroxetine binding in rat brain: effect of imipramine and tetrahydroacridine.
Topics: Aging; Animals; Brain; Imipramine; Male; Paroxetine; Rats; Rats, Inbred F344; Tacrine; Tritium | 1993 |
[3H]paroxetine binding and serotonin content of rat brain: absence of changes following antidepressant treatments.
Topics: Animals; Antidepressive Agents; Brain; Chromatography, High Pressure Liquid; Fluoxetine; Imipramine; Male; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Trimipramine | 1993 |
The serotonin transporter in depressed patients: a qualitative study based on dissociation kinetics.
Topics: Adult; Aged; Blood Platelets; Carrier Proteins; Citalopram; Female; Half-Life; Humans; Imipramine; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Paroxetine; Protein Binding; Serotonin; Serotonin Plasma Membrane Transport Proteins; Statistics, Nonparametric | 1995 |
[Adverse effects: priapism caused by paroxetine].
Topics: Adult; Antidepressive Agents; Cyproheptadine; Depressive Disorder; Humans; Imipramine; Male; Paroxetine; Priapism; Serotonin Antagonists | 1996 |
Comparison of [3H]paroxetine and [3H]cyanoimipramine for quantitative measurement of serotonin transporter sites in human brain.
Topics: Aged; Autoradiography; Binding Sites; Brain; Carrier Proteins; Female; Humans; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Paroxetine; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins | 1996 |
The serotonin transporter from human brain: purification and partial characterization.
Topics: Antidepressive Agents, Tricyclic; Brain Chemistry; Carrier Proteins; Chromatography, Affinity; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Female; Humans; Imipramine; In Vitro Techniques; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Membranes; Middle Aged; Neostriatum; Nerve Tissue Proteins; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins | 1996 |
The effects of paroxetine given repeatedly on the 5-HT receptor subpopulations in the rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain Chemistry; Electrophysiology; Hippocampus; Imipramine; Male; Motor Activity; Paroxetine; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists | 1996 |
Do glucocorticoids contribute to the abnormalities in serotonin transporter expression and function seen in depression? An animal model.
Topics: Animals; Blood Platelets; Brain; Carrier Proteins; Depressive Disorder; Dexamethasone; Disease Models, Animal; Gene Expression; Glucocorticoids; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins | 1996 |
Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography.
Topics: 20-alpha-Dihydroprogesterone; Adrenalectomy; Animals; Brain; Castration; Fluoxetine; GABA Modulators; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Imipramine; Male; Paroxetine; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley | 1996 |
Paroxetine shifts imipramine metabolism.
Topics: Adult; Antidepressive Agents, Tricyclic; Cytochrome P-450 Enzyme System; Depressive Disorder; Desipramine; Drug Synergism; Humans; Imipramine; Male; Middle Aged; Paroxetine; Selective Serotonin Reuptake Inhibitors | 1996 |
The effect of the potassium channel activator, cromakalim, on antidepressant drugs in the forced swimming test in mice.
Topics: Amitriptyline; Animals; Antidepressive Agents; Benzopyrans; Cromakalim; Desipramine; Drug Interactions; Imipramine; Locomotion; Male; Mianserin; Mice; Minoxidil; Paroxetine; Physical Exertion; Potassium Channels; Pyrroles; Swimming | 1996 |
Serotonin transporter expression in rat brain regions and blood platelets: aging and glucocorticoid effects.
Topics: Aging; Animals; Antidepressive Agents, Tricyclic; Blood Platelets; Brain Mapping; Carrier Proteins; Cerebral Cortex; Dexamethasone; Glucocorticoids; Hippocampus; Hypothalamo-Hypophyseal System; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptosomes | 1997 |
Protective effect of citalopram against the attenuation of the alpha 1-potentiation of cAMP formation in Fischer 344 strain rats.
Topics: Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Body Weight; Brain Chemistry; Citalopram; Cyclic AMP; Depression; Imipramine; Male; Motor Activity; Nerve Tissue Proteins; Paroxetine; Radioligand Assay; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha-1; Selective Serotonin Reuptake Inhibitors; Stress, Psychological | 1997 |
Regional distribution of specific high affinity binding sites for 3H-imipramine and 3H-paroxetine in human brain.
Topics: Adult; Aged; Brain; Humans; Imipramine; Male; Membrane Proteins; Middle Aged; Paroxetine; Protein Binding; Radioligand Assay; Tissue Distribution | 1997 |
Platelet [3H]imipramine and [3H]paroxetine binding in depressed patients.
Topics: Adult; Age Factors; Aged; Antidepressive Agents; Binding Sites; Blood Platelets; Depressive Disorder; Female; Humans; Imipramine; Male; Middle Aged; Paroxetine | 1997 |
Venlafaxine: in vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs, and effects on human hepatic CYP3A4, CYP2C9 and CYP1A2.
Topics: 1-Naphthylamine; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cyclohexanols; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desipramine; Fluoxetine; Fluvoxamine; Frozen Sections; Humans; Hydroxylation; Imipramine; In Vitro Techniques; Lethal Dose 50; Microsomes, Liver; Mixed Function Oxygenases; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Venlafaxine Hydrochloride | 1997 |
Cost-effectiveness of antidepressant treatment reassessed.
Topics: Antidepressive Agents, Tricyclic; Cost-Benefit Analysis; Humans; Imipramine; Paroxetine; Patient Satisfaction; Selective Serotonin Reuptake Inhibitors; Time Factors; Treatment Outcome | 1997 |
Serotonin syndrome: case report and review of the literature.
Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Drug Synergism; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Imipramine; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin; Syndrome | 1997 |
Influence of olfactory bulbectomy and subsequent imipramine treatment on 5-hydroxytryptaminergic presynapses in the rat frontal cortex: behavioural correlates.
Topics: Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Frontal Lobe; Imipramine; Male; Olfactory Bulb; Paroxetine; Presynaptic Terminals; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Tryptophan Hydroxylase | 1997 |
High affinity [3H]imipramine and [3H]paroxetine binding sites in suicide brains.
Topics: Adolescent; Adult; Aged; Binding Sites; Brain; Depression; Female; Humans; Imipramine; Male; Middle Aged; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin; Suicide | 1997 |
Individual differences in response to imipramine in the mouse tail suspension test.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Behavior, Animal; Depression; Desipramine; Disease Models, Animal; Imipramine; Individuality; Male; Mice; Mice, Inbred Strains; Motor Activity; Paroxetine; Restraint, Physical | 1997 |
Enhanced displacement of [3H]imipramine, but not [3H]paroxetine binding by plasma from depressed patients.
Topics: Adult; Binding, Competitive; Blood Platelets; Blood Proteins; Cell Membrane; Depressive Disorder; Female; Humans; Imipramine; Immunodiffusion; Male; Middle Aged; Orosomucoid; Paroxetine; Platelet Membrane Glycoproteins; Radioligand Assay; Receptors, Serotonin; Tritium | 1997 |
Variations in [3H]imipramine and 5-HT2A but not [3H]paroxetine binding sites in suicide brains.
Topics: Adult; Aged; Amygdala; Antidepressive Agents, Tricyclic; Brain Chemistry; Carrier Proteins; Female; Frontal Lobe; Gyrus Cinguli; Hippocampus; Humans; Imipramine; Male; Middle Aged; Paroxetine; Receptors, Drug; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Suicide | 1998 |
Distribution of paroxetine in three postmortem cases.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Desipramine; Drug Interactions; Drug Overdose; Fatal Outcome; Female; Humans; Imipramine; Male; Middle Aged; Paroxetine; Suicide; Tissue Distribution | 1998 |
Inhibition by tetanus toxin of sodium-dependent, high-affinity [3H]5-hydroxytryptamine uptake in rat synaptosomes.
Topics: Animals; Biological Transport; Botulinum Toxins; Brain; Captopril; Fenfluramine; Imipramine; Kinetics; Male; Organ Specificity; Paroxetine; Phenanthrolines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sodium; Synaptosomes; Temperature; Tetanus Toxin; Tritium | 1999 |
The 5-HT2B receptor controls the overall 5-HT transport system in the 1C11 serotonergic cell line.
Topics: Animals; Carrier Proteins; Cell Differentiation; Cell Line; Clone Cells; Imipramine; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; Paroxetine; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Stem Cells | 1998 |
Pharmacoeconomic issues in the treatment of depression.
Topics: Algorithms; Antidepressive Agents; Cost of Illness; Cost-Benefit Analysis; Depression; Drug Costs; Humans; Imipramine; Models, Economic; Paroxetine; United States | 1995 |
Cost analysis of paroxetine versus imipramine in major depression.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Computer Simulation; Costs and Cost Analysis; Depressive Disorder; Humans; Imipramine; Insurance, Health, Reimbursement; Models, Economic; Paroxetine; Patient Dropouts; Recurrence; Treatment Failure; United States | 1995 |
Molecular cloning, expression and characterization of a bovine serotonin transporter.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cattle; Citalopram; Cloning, Molecular; Desipramine; Female; Fluoxetine; HeLa Cells; Humans; Imipramine; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Organ Specificity; Paroxetine; Phylogeny; Pregnancy; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin; Serotonin Plasma Membrane Transport Proteins; Transfection | 1999 |
Increased tonic activation of rat forebrain 5-HT(1A) receptors by lithium addition to antidepressant treatments.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Depressive Disorder; Drug Therapy, Combination; Free Radical Scavengers; Hippocampus; Imipramine; Lithium; Male; Monoamine Oxidase Inhibitors; Paroxetine; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Tranylcypromine | 2000 |
Are there gender differences in the temperature profile of mice after acute antidepressant administration and exposure to two animal models of depression?
Topics: Animals; Arousal; Body Temperature Regulation; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Imipramine; Male; Mice; Motivation; Motor Activity; Paroxetine; Sex Factors | 2001 |
Lack of interaction between flibanserin and antidepressants in inducing serotonergic syndrome in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Benzimidazoles; Drug Interactions; Fluoxetine; Imipramine; Male; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Serotonin Syndrome | 2001 |
Mood disorders in children and adolescents: psychopharmacological treatment.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Child; Depressive Disorder, Major; Drug Therapy, Combination; Fluoxetine; Health Services Needs and Demand; Humans; Imipramine; Mood Disorders; Paroxetine; Selective Serotonin Reuptake Inhibitors | 2001 |
Effects of Hypericum perforatum (St. John's wort) on passive avoidance in the rat: evaluation of potential neurochemical mechanisms underlying its antidepressant activity.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Avoidance Learning; Behavior, Animal; Brain Chemistry; Desipramine; Hypericum; Imipramine; Male; Muscarinic Antagonists; Norepinephrine; Paroxetine; Plant Extracts; Rats; Rats, Sprague-Dawley; Scopolamine; Serotonin | 2001 |
Effect of chronic treatment with milnacipran on sleep architecture in rats compared with paroxetine and imipramine.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Behavior, Animal; Body Weight; Cyclopropanes; Imipramine; Male; Milnacipran; Paroxetine; Rats; Selective Serotonin Reuptake Inhibitors; Sleep; Sleep Stages; Sleep, REM; Wakefulness | 2002 |
Different distributions of the 5-HT reuptake complex and the postsynaptic 5-HT(2A) receptors in Brodmann areas and brain hemispheres.
Topics: Adult; Brain Mapping; Carrier Proteins; Cerebral Cortex; Dominance, Cerebral; Gyrus Cinguli; Humans; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptors, Presynaptic; Receptors, Serotonin; Serotonin Plasma Membrane Transport Proteins | 2002 |
Paroxetine in the treatment of adolescent major depression.
Topics: Adolescent; Depressive Disorder, Major; Drug Monitoring; Humans; Imipramine; Paroxetine; Selective Serotonin Reuptake Inhibitors | 2002 |
Paroxetine in the treatment of adolescent major depression.
Topics: Adolescent; Depressive Disorder, Major; Drug Monitoring; Humans; Imipramine; Paroxetine; Selective Serotonin Reuptake Inhibitors | 2002 |
Influence of antidepressants on intracellular levels of cyclic adenosine monophosphate in human peripheral blood mononuclear cells.
Topics: Antidepressive Agents; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Imipramine; In Vitro Techniques; Leukocytes, Mononuclear; Lipopolysaccharides; Paroxetine; Phytohemagglutinins | 2003 |
Local, but not systemic, administration of serotonergic antidepressants decreases hippocampal nitric oxide synthase activity.
Topics: Animals; Cells, Cultured; Citalopram; Hippocampus; Imipramine; Male; Microdialysis; Nitric Oxide; Nitroarginine; Paroxetine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiazepines; Time Factors | 2003 |
A comparison of drug effects in latent inhibition and the forced swim test differentiates between the typical antipsychotic haloperidol, the atypical antipsychotics clozapine and olanzapine, and the antidepressants imipramine and paroxetine.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzodiazepines; Clozapine; Conditioning, Psychological; Haloperidol; Imipramine; Inhibition, Psychological; Male; Models, Animal; Olanzapine; Paroxetine; Pirenzepine; Rats; Rats, Wistar; Swimming | 2003 |
Antidepressant-like effects in various mice strains in the tail suspension test.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Bupropion; Citalopram; Depression; Desipramine; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Hindlimb Suspension; Imipramine; Male; Mice; Mice, Inbred Strains; Paroxetine; Selective Serotonin Reuptake Inhibitors; Species Specificity | 2003 |
Are selective serotonin re-uptake inhibitors associated with an increased risk of self-harm by antidepressant overdose?
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Citalopram; Cyclohexanols; Doxepin; Drug Overdose; Drug Prescriptions; Emergency Service, Hospital; Female; Fluoxetine; Humans; Imipramine; Information Services; Male; Mianserin; Mirtazapine; Paroxetine; Patient Admission; Patient Readmission; Poison Control Centers; Retrospective Studies; Risk Assessment; Scotland; Selective Serotonin Reuptake Inhibitors; Self-Injurious Behavior; Sertraline; Trazodone; Venlafaxine Hydrochloride | 2004 |
Role of the orbital cortex and of the serotonergic system in a rat model of obsessive compulsive disorder.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Frontal Lobe; Imipramine; Male; Obsessive-Compulsive Disorder; Paroxetine; Protein Binding; Random Allocation; Rats; Rats, Wistar; Serotonin; Tritium | 2005 |
Selective serotonin reuptake inhibitors induce spontaneous interneuronal activity in the leech nervous system.
Topics: Action Potentials; Adrenergic Uptake Inhibitors; Animals; Citalopram; Drug Interactions; Electric Stimulation; Fluoxetine; Ganglia, Invertebrate; Imipramine; In Vitro Techniques; Interneurons; Leeches; Membrane Potentials; Neural Networks, Computer; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin; Synapses | 2005 |
Platelet serotonergic markers as endophenotypes for obsessive-compulsive disorder.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Biomarkers; Blood Platelets; Case-Control Studies; Child; Female; Genotype; Humans; Imipramine; Inositol 1,4,5-Trisphosphate; Iodine Isotopes; Lysergic Acid Diethylamide; Male; Middle Aged; Minisatellite Repeats; Obsessive-Compulsive Disorder; Paroxetine; Radioimmunoassay; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Statistics as Topic; Statistics, Nonparametric; Tritium | 2005 |
Late developmental stage-specific role of tryptophan hydroxylase 1 in brain serotonin levels.
Topics: Animals; Antidepressive Agents; Biopterins; Brain; Chlorocebus aethiops; COS Cells; Depression; Enzyme Induction; Freezing Reaction, Cataleptic; Gene Expression Regulation, Developmental; Humans; Imipramine; Mice; Mice, Inbred Strains; Paroxetine; Raphe Nuclei; Recombinant Fusion Proteins; RNA, Messenger; Serotonin; Tryptophan; Tryptophan Hydroxylase | 2006 |
Effect of antidepressant drugs on 6-OHDA-treated mice in the FST.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Biogenic Monoamines; Cerebral Cortex; Citalopram; Depression; Desipramine; Dopamine Uptake Inhibitors; Hippocampus; Hypothalamus; Imipramine; Injections, Intraventricular; Male; Mice; Neostriatum; Oxidopamine; Paroxetine; Swimming | 2007 |
Effects of acute and chronic antidepressant treatments on memory performance: a comparison between paroxetine and imipramine.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Behavior, Animal; Drug Administration Schedule; Imipramine; Male; Maze Learning; Memory; Paroxetine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Space Perception | 2007 |
Antidepressant use and off-label prescribing in children and adolescents in Dutch general practice (2001-2005).
Topics: Adolescent; Adrenergic Uptake Inhibitors; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Child; Cyclohexanols; Depressive Disorder; Drug Labeling; Drug Prescriptions; Drug Utilization; Family Practice; Female; Humans; Imipramine; Male; Netherlands; Nocturnal Enuresis; Paroxetine; Practice Patterns, Physicians'; Selective Serotonin Reuptake Inhibitors; Tension-Type Headache; Time Factors; Venlafaxine Hydrochloride | 2007 |
In vivo effect of antidepressants on [3H]paroxetine binding to serotonin transporters in rat brain.
Topics: Animals; Antidepressive Agents, Second-Generation; Brain; Imipramine; Male; Paroxetine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Tritium | 2008 |
Involvement of pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors in the mechanism of antidepressant action.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Cells, Cultured; Citalopram; Imipramine; Neurons; Paroxetine; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Sprague-Dawley; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Selective Serotonin Reuptake Inhibitors; Signal Transduction | 2008 |
Effects of antidepressants on GluR2 Q/R site-RNA editing in modified HeLa cell line.
Topics: Adenosine Deaminase; Amitriptyline; Amyotrophic Lateral Sclerosis; Antidepressive Agents; Arginine; Cyclopropanes; Desipramine; Fluoxetine; Fluvoxamine; Glutamine; HeLa Cells; Humans; Imipramine; Milnacipran; Morpholines; Paroxetine; Reboxetine; Receptors, AMPA; RNA Editing; RNA-Binding Proteins; RNA, Messenger | 2009 |
Antidepressant stimulation of CDP-diacylglycerol synthesis does not require monoamine reuptake inhibition.
Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Cerebral Cortex; Cytidine Diphosphate Diglycerides; Diacylglycerol Cholinephosphotransferase; Dose-Response Relationship, Drug; Hippocampus; Imipramine; Male; Maprotiline; Mice; Mice, Inbred C57BL; Paroxetine; PC12 Cells; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins | 2010 |
Interaction of selective serotonin reuptake inhibitors with neuronal nicotinic acetylcholine receptors.
Topics: Antidepressive Agents, Tricyclic; Fluoxetine; Humans; Imipramine; Ion Channels; Molecular Conformation; Neurons; Paroxetine; Receptors, Cholinergic; Receptors, Nicotinic; Selective Serotonin Reuptake Inhibitors | 2010 |
Antidepressants inhibit DNA methyltransferase 1 through reducing G9a levels.
Topics: Animals; Antidepressive Agents; Astrocytes; Carbamazepine; Cells, Cultured; Cerebral Cortex; Citalopram; Cyclohexanols; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Glycolipids; Histone-Lysine N-Methyltransferase; Imipramine; Indoles; Maleimides; Mice; Nerve Tissue Proteins; Neural Stem Cells; Neurons; Paroxetine; Protein Interaction Mapping; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Venlafaxine Hydrochloride | 2012 |
Test-retest paradigm of the forced swimming test in female mice is not valid for predicting antidepressant-like activity: participation of acetylcholine and sigma-1 receptors.
Topics: Acetylcholine; Animals; Anisoles; Antidepressive Agents; Cholinergic Antagonists; Female; Forecasting; Imipramine; Mice; Mice, Inbred ICR; Motor Activity; Paroxetine; Propylamines; Receptors, sigma; Scopolamine; Stress, Psychological; Swimming | 2013 |
Effects of antidepressant drugs on synaptic protein levels and dendritic outgrowth in hippocampal neuronal cultures.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cell Enlargement; Cells, Cultured; Citalopram; Dendrites; Fluoxetine; Hippocampus; Imipramine; Nerve Tissue Proteins; Neurons; Paroxetine; Rats; Rats, Sprague-Dawley; Sertraline; Thiazepines; Tranylcypromine | 2014 |
Disruption of running activity rhythm following restricted feeding in female mice: Preventive effects of antidepressants.
Topics: Animals; Antidepressive Agents; Chronobiology Disorders; Circadian Rhythm; Feeding Behavior; Imipramine; Isoindoles; Male; Mice, Inbred ICR; Paroxetine; Piperazines; Pyrimidines; Running; Sex Characteristics | 2015 |
Effect of Imipramine, Paroxetine, and Lithium Carbonate on Neurobehavioral Changes of Streptozotocin in Rats: Impact on Glycogen Synthase Kinase-3 and Blood Glucose Level.
Topics: Animals; Behavior, Animal; Blood Glucose; Diabetes Mellitus, Experimental; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Imipramine; Lithium Carbonate; Male; Paroxetine; Rats; Rats, Sprague-Dawley; Streptozocin; Swimming | 2015 |
Restoring Study 329: results differ with the adverse event classification system used.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Humans; Imipramine; Paroxetine | 2015 |
Authors' reply to Sasich and Linden.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Humans; Imipramine; Paroxetine | 2015 |
Paroxetine and Study 329: what we already knew and when.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Humans; Imipramine; Paroxetine | 2015 |
Both paroxetine and imipramine appear to be ineffective in adolescents with major depression, furthermore doubts have risen about their safety.
Topics: Adolescent; Antidepressive Agents; Depressive Disorder, Major; Humans; Imipramine; Paroxetine | 2016 |
Comparison of the Efficiency of Adeprophen and Antidepressants of Various Groups on the Model of Reserpine-Induced Depression in Rats.
Topics: Adenine; Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Fluoxetine; Food Preferences; Imipramine; Male; Motor Activity; Paroxetine; Rats; Reserpine; Sertraline; Venlafaxine Hydrochloride | 2016 |
Effects of Adjuvant Analgesics on Cerebral Ischemia-Induced Mechanical Allodynia.
Topics: Amines; Analgesics; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Brain Ischemia; Carbamazepine; Chemotherapy, Adjuvant; Cyclohexanecarboxylic Acids; Cyclopropanes; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Imipramine; Indomethacin; Male; Mexiletine; Mice; Milnacipran; Morphine; Neuralgia; Paroxetine; Selective Serotonin Reuptake Inhibitors | 2016 |
Antidepressant-like activity of liposomal formulation containing nimodipine treatment in the tail suspension test, forced swim test and MAOB activity in mice.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Behavior, Animal; Calcium Channel Blockers; Depressive Disorder; Hindlimb Suspension; Hippocampus; Imipramine; Liposomes; Male; Mice; Monoamine Oxidase; Nimodipine; Paroxetine | 2016 |