imipramine and papaverine

imipramine has been researched along with papaverine in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199014 (50.00)18.7374
1990's1 (3.57)18.2507
2000's6 (21.43)29.6817
2010's7 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Caron, G; Ermondi, G1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Gozalbes, R; Pineda-Lucena, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Sen, S; Sinha, N1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Farbiszewski, R; Niewiarowski, S; Poplawski, A1
Bârzu, T; Brief, G; Csutak, W; Cuparencu, B; Steiner, L; Ticşa, I1
Berndt, S; Ebert, R; Schwabe, U1
Kocher, R; Rohrer, G1
Spilker, BA; van Balken, H1
Gordon, JL1
Bounameaux, Y1
Imamura, H; Maruyama, Y; Nakanishi, M1
Bertazzoli, C; Bonsignori, A; Chieli, T; Pegrassi, L; Suchowsky, GK1
Rosazza, JP; Smith, RV1
Dawson, CA; Linehan, JH; Rickaby, DA1
Halaska, M; Martan, A; Voigt, R1
MARIANI, L1
WASILEWSKA, L1
Borka-Balás, R; Donáth-Nagy, G; Gáll, Z; Vancea, S1

Reviews

1 review(s) available for imipramine and papaverine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for imipramine and papaverine

ArticleYear
[Treatment of severe chronic pains with a combination of thymoleptics and neuroleptics (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1974, Dec-31, Volume: 63, Issue:52

    Topics: Adult; Antidepressive Agents; Atropine; Chlorpromazine; Clinical Trials as Topic; Clomipramine; Drug Combinations; Female; Haloperidol; Humans; Imipramine; Male; Methotrimeprazine; Middle Aged; Morphine; Neoplasms; Pain; Papaverine; Tranquilizing Agents

1974

Other Studies

26 other study(ies) available for imipramine and papaverine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[Effect of various drugs on platelet aggregation and liberation of platelet factor 4 (anti-heparin factor)].
    Folia haematologica (Leipzig, Germany : 1928), 1969, Volume: 92, Issue:4

    Topics: Animals; Anticoagulants; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Chloroquine; Citrates; Fibrinogen; Fibrinolysis; Heparin Antagonists; Imipramine; Ouabain; Papaverine; Phentolamine; Phenylbutazone; Platelet Adhesiveness; Rabbits; Sodium Salicylate

1969
[Pharmacological analysis of erythrocyte reaction to hypobarism].
    Folia haematologica (Leipzig, Germany : 1928), 1970, Volume: 93, Issue:1

    Topics: Altitude; Amphetamine; Animals; Antidepressive Agents; Antihypertensive Agents; Atmospheric Pressure; Atropine; Benactyzine; Bone Marrow Examination; Bretylium Compounds; Dibenzylchlorethamine; Erythrocyte Count; Erythrocytes; Guanethidine; Hexamethonium Compounds; Imipramine; Mice; Nialamide; Papaverine; Reserpine; Reticulocytes

1970
Activation and inhibition of lipolysis in isolated fat cells by various inhibitors of cyclic AMP phosphodiesterase.
    Naunyn-Schmiedeberg's archives of pharmacology, 1972, Volume: 273, Issue:1

    Topics: Adipose Tissue; Animals; Binding Sites; Cattle; Cyclic AMP; Dipyridamole; Drug Antagonism; Imipramine; Lipid Metabolism; Male; Norepinephrine; Papaverine; Phosphoric Monoester Hydrolases; Phosphotransferases; Rats; Theophylline; Xanthines

1972
Formation and embolization of thrombi after electrical stimulation. On the method and evaluation of drugs.
    Thrombosis et diathesis haemorrhagica, 1973, Volume: 30, Issue:2

    Topics: Animals; Aspirin; Cats; Cranial Sinuses; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electric Stimulation; Female; Guinea Pigs; Heparin; Imipramine; Male; Mesenteric Arteries; Mesenteric Veins; Methods; Mice; Papaverine; Phenoxybenzamine; Platelet Adhesiveness; Rabbits; Rats; Streptokinase; Thromboembolism; Time Factors

1973
Differential changes in potency of platelet-aggregation inhibitors after preincubation in platelet-rich plasma.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 7, Issue:1

    Topics: Adenosine Diphosphate; Amitriptyline; Animals; Caffeine; Chlorpromazine; Diphenhydramine; Dipyridamole; Imipramine; Papaverine; Plasma; Platelet Adhesiveness; Swine; Time Factors; Trifluoperazine

1974
[Pharmacodynamic prevention of thrombosis].
    Revue medicale de Liege, 1971, Oct-01, Volume: 26, Issue:19

    Topics: Adenosine Diphosphate; Amitriptyline; Anticoagulants; Aspirin; Collagen; Dipyridamole; Guanethidine; Humans; Imipramine; Papaverine; Thrombin; Thrombosis

1971
[Studies on anti-inflammatory agents. II. Analgesic and anti-edematous activities of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6, 7-tetrahydrothieno (2,3-c)pyridine (Y-3642)].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1970, Volume: 90, Issue:3

    Topics: Aminopyrine; Amphetamine; Analgesics; Animals; Anti-Inflammatory Agents; Edema; Imipramine; Male; Mice; Morphine; Pain; Papaverine; Phenylbutazone; Pyridines; Rats; Salicylates; Thiophenes

1970
Some pharmacological properties of 4H-3-methylcarboxamide 1,3-benzoxazine-2-one (FI 6654).
    European journal of pharmacology, 1969, Volume: 6, Issue:3

    Topics: Acetylcholine; Animals; Antidepressive Agents; Arousal; Atropine; Barium; Duodenum; Electroencephalography; Guinea Pigs; Histamine; Ileum; Imipramine; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Nicotine; Oxazines; Papaverine; Physostigmine; Rabbits; Rats; Seizures; Serotonin

1969
Microbial models of mammalian metabolism.
    Journal of natural products, 1983, Volume: 46, Issue:1

    Topics: Acronine; Animals; Apomorphine; Biotransformation; Dealkylation; Ellipticines; Ergolines; Guinea Pigs; Humans; Hydroxylation; Imipramine; Mammals; Models, Biological; Papaverine; Pharmaceutical Preparations

1983
Influence of embolism and imipramine on kinetics of serotonin uptake by dog lung.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1984, Volume: 56, Issue:5

    Topics: Animals; Capillary Permeability; Dogs; Dose-Response Relationship, Drug; Endothelium; Imipramine; Kinetics; Lung; Papaverine; Pulmonary Circulation; Pulmonary Embolism; Serotonin; Ventilation-Perfusion Ratio

1984
[Drug therapy of urge incontinence in the female].
    Zentralblatt fur Gynakologie, 1993, Volume: 115, Issue:5

    Topics: Adult; Aged; Diltiazem; Female; Humans; Imipramine; Middle Aged; Oxyphenonium; Papaverine; Parasympatholytics; Sulfonium Compounds; Urinary Incontinence, Stress; Urodynamics

1993
[Drugs antagonistic to bradykinin].
    Bollettino della Societa italiana di biologia sperimentale, 1961, Dec-31, Volume: 37

    Topics: Anti-Allergic Agents; Atropine; Bradykinin; Chlorpromazine; Ergotamine; Histamine H1 Antagonists; Imipramine; Lysergic Acid Diethylamide; Papaverine; Phenylbutazone; Promazine; Promethazine

1961
[A NEW COMPLEXOMETRIC METHOD FOR THE DETERMINATION OF ORGANIC BASES].
    Acta poloniae pharmaceutica, 1963, Volume: 20

    Topics: Chemistry, Pharmaceutical; Chlorpromazine; Imipramine; Papaverine; Promethazine; Research; Succinylcholine

1963
Rapid LC-MS/MS method for determination of drotaverine in a bioequivalence study.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 98

    Topics: Chromatography, Liquid; Humans; Imipramine; Methanol; Papaverine; Plasma; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Therapeutic Equivalency

2014