imipramine and orphenadrine

imipramine has been researched along with orphenadrine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199018 (66.67)18.7374
1990's1 (3.70)18.2507
2000's3 (11.11)29.6817
2010's5 (18.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Sen, S; Sinha, N1
Giacomini, KM; Kido, Y; Matsson, P1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ambrogi, F; Cassano, GB; Marazziti, D; Rotondo, A1
Chandra, O; Dhawan, KN; Gupta, GP; Saxena, RC1
Clark, MS; Palfreyman, ES; Palfreyman, MG1
Hespe, W; van der Zee, P1
Dresse, A; Van Dorsser, W1
Hall, P1
Florio, V; Longo, VG1
Bhargava, KP; Dixit, KS; Sinha, JN; Srimal, RC1
Roberts, E; Varon, S; Weinstein, H1
Sangster, B; Zandberg, P2
BALLERINI, A; MAGHERINI, G; SACCHETTINI, B1
BEGHI, Q1
GILLINGHAM, FJ; KALYANARAMAN, S1
ROTH, M1
CURRAN, DA; LANCE, JW1
PERRIN, J; SCHNEIDER, J; SIFFERMANN, A; THOMALSKE, G1
BASTECKY, J1
TAIT, AC; TODRICK, A; YATES, CM1

Reviews

1 review(s) available for imipramine and orphenadrine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

26 other study(ies) available for imipramine and orphenadrine

ArticleYear
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.
    Journal of medicinal chemistry, 2011, Jul-14, Volume: 54, Issue:13

    Topics: Drug Interactions; HEK293 Cells; High-Throughput Screening Assays; Humans; Kidney; Ligands; Models, Molecular; Molecular Structure; Organic Cation Transport Proteins; Organic Cation Transporter 2; Polymorphism, Genetic; Prescription Drugs; Protein Binding; Small Molecule Libraries; Structure-Activity Relationship

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Analgesia by nefopam: does it act through serotonin?
    Drugs under experimental and clinical research, 1991, Volume: 17, Issue:5

    Topics: Analgesia; Blood Platelets; Desipramine; Dose-Response Relationship, Drug; Humans; Imipramine; Morphine; Nefopam; Orphenadrine; Serotonin Antagonists

1991
Assessment of anti-reserpine and anti-apomorphine activities of some psychic energizers in pigeons.
    Psychopharmacologia, 1969, Volume: 15, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents; Apomorphine; Columbidae; Deanol; Desipramine; Female; Hydrazines; Imipramine; Male; Opipramol; Orphenadrine; Reserpine; Vomiting

1969
Effects of benapyrzine, a new antiparkinson drug, on dopamine uptake into corpus striatum.
    European journal of pharmacology, 1974, Volume: 28, Issue:2

    Topics: Animals; Antiparkinson Agents; Benzilates; Catecholamines; Corpus Striatum; Dopamine; Ethylamines; Female; Hypothalamus; Imipramine; In Vitro Techniques; Kinetics; Orphenadrine; Propylamines; Rats; Scopolamine; Synaptosomes; Trihexyphenidyl; Tritium

1974
Influence of orphenadrine HC1 and its N-demethylated derivatives on the in vitro uptake of noradrenaline and 5-hydroxytryptamine by rat brain slices.
    Neuropharmacology, 1973, Volume: 12, Issue:9

    Topics: Animals; Brain; Carbon Radioisotopes; Desipramine; Germ-Free Life; Imipramine; In Vitro Techniques; Kinetics; Male; Norepinephrine; Orphenadrine; Rats; Serotonin

1973
[Comparative effects of various antidepressants on the response to noradrenaline of the deferent canal and the arterial pressure, and the response to 5-hydroxytryptamine of the rat uterus].
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 208, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Blood Pressure; Carotid Arteries; Clomipramine; Dibenzazepines; Dose-Response Relationship, Drug; Drug Interactions; Female; Imipramine; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Orphenadrine; Quinuclidines; Rats; Serotonin; Uterus; Vas Deferens

1974
Differential diagnosis and treatment of depression in the elderly.
    Gerontologia clinica, 1974, Volume: 16, Issue:1

    Topics: Adjustment Disorders; Aged; Antidepressive Agents; Circadian Rhythm; Dementia; Depression; Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Ethanol; Humans; Imipramine; Iprindole; Middle Aged; Monoamine Oxidase Inhibitors; Nortriptyline; Orphenadrine; Physiognomy; Piperazines; Thioxanthenes

1974
Effects of amantadine and of some synthetic antiparkinsonian drugs on the behavioral response to L-DOPA in mice.
    Physiology & behavior, 1971, Volume: 6, Issue:4

    Topics: Amantadine; Amitriptyline; Animals; Antiparkinson Agents; Atropine; Behavior, Animal; Dihydroxyphenylalanine; Diphenhydramine; Drug Synergism; Imipramine; Mice; Orphenadrine; Parasympatholytics; Pargyline; Trihexyphenidyl

1971
Central muscle relaxant activity of a dozen CNS active agents and a correlation with their psychotropic activity.
    Japanese journal of pharmacology, 1968, Volume: 18, Issue:1

    Topics: Amphetamine; Animals; Antidepressive Agents; Blood Pressure; Cats; Central Nervous System; Chlorpromazine; Desipramine; Dibenzothiazepines; Ephedrine; Female; Imipramine; Iproniazid; Male; Mephenesin; Monoamine Oxidase Inhibitors; Muscles; Orphenadrine; Phenelzine; Reflex; Thioridazine; Tranquilizing Agents

1968
Effects of imipramine on the Na+-dependent exchange and retention of gamma-aminobutyric acid by mouse brain subcellular particles.
    Biochemical pharmacology, 1971, Volume: 20, Issue:1

    Topics: Adsorption; Aminobutyrates; Animals; Biological Transport; Brain; Carbon Isotopes; Chlorpromazine; Imipramine; In Vitro Techniques; Kinetics; Mathematics; Membranes; Mice; Orphenadrine; Potassium Chloride; Receptors, Drug; Sodium Chloride; Time Factors; Tritium

1971
The influence of orphenadrine or imipramine on the hypertensive response of physostigmine in the rat.
    Acta pharmacologica et toxicologica, 1983, Volume: 52, Issue:3

    Topics: Animals; Blood Pressure; Electric Stimulation; Heart Rate; Hypothalamus; Imipramine; Male; Norepinephrine; Orphenadrine; Physostigmine; Rats; Rats, Inbred Strains; Sympathetic Nervous System

1983
The influence of physostigmine on respiratory and circulatory changes caused by overdoses of orphenadrine or imipramine in the rat.
    Acta pharmacologica et toxicologica, 1982, Volume: 50, Issue:3

    Topics: Animals; Blood Gas Analysis; Blood Pressure; Cardiac Output; Electrocardiography; Hemodynamics; Imipramine; Male; Orphenadrine; Physostigmine; Rats; Respiration

1982
[Observations of groups of psychopaths treated with various psychopharmacological drugs (reserpine with orphenadrine, imipramine, levomepromazine)].
    Rassegna di studi psichiatrici, 1960, Volume: 49

    Topics: Electroconvulsive Therapy; Humans; Imipramine; Methotrimeprazine; Orphenadrine; Psychopharmacology; Psychosurgery; Psychotherapy; Psychotic Disorders; Reserpine

1960
[PSYCHIATRIC USE OF SOME PSYCHOPHARMACOLOGICAL DRUGS IN PREGNANCY].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1963, Jun-30, Volume: 87

    Topics: Chlordiazepoxide; Chlorpromazine; Fetus; Haloperidol; Imipramine; Isocarboxazid; Meprobamate; Nialamide; Orphenadrine; Perphenazine; Pharmacology; Pregnancy; Prochlorperazine; Promazine; Psychopharmacology; Reserpine; Thalidomide; Thioridazine

1963
PARKINSON'S DISEASE.
    Physiotherapy, 1963, Dec-10, Volume: 49

    Topics: Amitriptyline; Dextroamphetamine; Humans; Imipramine; Muscle Relaxants, Central; Neurosurgery; Orphenadrine; Parasympatholytics; Parkinson Disease; Parkinsonian Disorders; Pathology; Stereotaxic Techniques; Trihexyphenidyl

1963
DEPRESSIVE AND MANIC PSYCHOSES AND ALLIED DISORDERS.
    Current medicine and drugs, 1964, Volume: 4, Issue:8

    Topics: Adolescent; Amitriptyline; Antidepressive Agents; Barbiturates; Bipolar Disorder; Depression; Electroconvulsive Therapy; Geriatrics; Haloperidol; Humans; Imipramine; Lithium; Mental Disorders; Middle Aged; Orphenadrine; Psychotherapy; Psychotic Disorders

1964
TREATMENT OF CHRONIC TENSION HEADACHE.
    Lancet (London, England), 1964, Jun-06, Volume: 1, Issue:7345

    Topics: Amitriptyline; Amobarbital; Anxiety; Anxiety Disorders; Biomedical Research; Chlordiazepoxide; Diazepam; Ergot Alkaloids; Ergotamine; Headache; Headache Disorders; Imipramine; Methysergide; Orphenadrine; Phenobarbital; Placebos; Psychosomatic Medicine; Selective Serotonin Reuptake Inhibitors; Serotonin; Tension-Type Headache; Tranquilizing Agents; Tranylcypromine; Trifluoperazine; Vasodilator Agents

1964
[MODIFICATIONS OF THE EEG DUE TO PSYCHOPHARMACOLOGICAL TREATMENT. LONG-TERM STUDIES ON MENTAL PATIENTS].
    Der Nervenarzt, 1963, Volume: 34

    Topics: Bemegride; Chlormethiazole; Chlorpromazine; Electroencephalography; Haloperidol; Humans; Hypnotics and Sedatives; Imipramine; Mental Disorders; Mentally Ill Persons; Meprobamate; Methotrimeprazine; Orphenadrine; Phenothiazines; Prochlorperazine; Psychopharmacology; Sympathomimetics; Trimeprazine

1963
[ACUTE POISONING WITH PSYCHOMIMETICS].
    Activitas nervosa superior, 1964, Volume: 6

    Topics: Amphetamine; Amphetamines; Central Nervous System Stimulants; Imipramine; Methylphenidate; Orphenadrine; Phenmetrazine; Toxicology

1964
EFFECT OF IMIPRAMINE AND SOME ANALOGUES ON THE UPTAKE OF 5-HYDROXYTRYPTAMINE BY HUMAN BLOOD PLATELETS IN VITRO.
    The Journal of pharmacy and pharmacology, 1964, Volume: 16

    Topics: Amitriptyline; Antidepressive Agents; Blood Platelets; Chlorpromazine; Desipramine; Humans; Imipramine; In Vitro Techniques; Metabolism; Orphenadrine; Pharmacology; Research; Serotonin

1964