imipramine has been researched along with nortriptyline in 317 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 243 (76.66) | 18.7374 |
| 1990's | 26 (8.20) | 18.2507 |
| 2000's | 24 (7.57) | 29.6817 |
| 2010's | 18 (5.68) | 24.3611 |
| 2020's | 6 (1.89) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Dudley, MW; Kane, JM; Miller, FP; Sorensen, SM | 1 |
| Chiang, GH; Unger, SH | 1 |
| Medina-Hernández, MJ; Quiñones-Torrelo, C; Sagrado, S; Villanueva-Camañas, RM | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Ikeda, K; Kobayashi, T; Washiyama, K | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Goetz, RM; Karpowich, NK; Law, CJ; Reith, ME; Wang, DN; Zhen, J; Zhou, Z | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Dalvie, D; Loi, CM; Smith, DA | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Cardoso, FC; Duggan, PJ; Kuiper, MJ; Lewis, RJ; Schmit, M; Tuck, KL | 1 |
| Modestin, J; Petrin, A | 1 |
| Hollister, LE | 3 |
| Bissada, NK; Finkbeiner, AE; Welch, LT | 1 |
| Richelson, E | 1 |
| Aherne, GW; Marks, V; Mould, G; Stout, G | 1 |
| Levine, RM; Maickel, RP; Spaulding, JH; Zabik, JE | 1 |
| Bickel, MH | 1 |
| Braithwaite, R | 1 |
| Hullin, RP | 1 |
| Dorrity, F; Jobson, K; Linnoila, M | 1 |
| Dujovne, CA; Ueda, I; Yasuhara, H | 1 |
| Oei, LS; Rodstein, M | 1 |
| Hedley, LR; Wallach, MB | 1 |
| Gupta, R; Molnar, G; Wallace, J | 1 |
| Chodera, A; Godlewski, J; Konkiewicz, B; Nowakowska, E | 1 |
| Aherne, GW; Marks, V; Mould, GP; Stout, G | 1 |
| Biggs, JT; Petit, JM; Spiker, DG; Ziegler, VE | 1 |
| Adams, RF; Schmidt, GJ; Vandemark, FL | 1 |
| Davis, CM; Fenimore, DC; Meyer, CJ | 1 |
| Bailey, DN; Jatlow, PI; Langou, RA; Van Dyke, C | 1 |
| Lohmann, HJ; Miles, DG; Proelss, HF | 1 |
| Bourgeois, ML; Tignol, J | 1 |
| Goedde, HW; Schloot, W | 1 |
| Lauer, JW | 1 |
| Baum, T; Butz, F; Much, DR; Peters, JR | 1 |
| Andreasen, PB; Christiansen, J; Gram, LF; Overo, KF | 1 |
| Stewart, MJ; Watson, ID | 1 |
| Cooper, TB; Friedman, MJ; Green, R; Ives, JO; Nies, A; Ravaris, CL; Robinson, DS | 1 |
| Maayani, S; Rehavi, M; Sokolovsky, M | 1 |
| Davis, CM; Fenimore, DC; Hsu, F; Meyer, CJ; Zlatkis, A | 1 |
| Baba, O; Fujiwara, J; Hanaoka, M; Ishino, H; Sasaki, K | 1 |
| Breyer, U; Villumsen, K | 1 |
| Burrows, GD; Davies, B; Hunt, D; Scoggins, BA; Sloman, JG; Vohra, J | 1 |
| Detaevernier, MR; Dryon, L; Massart, DL | 1 |
| Banazdkiewicz, W; Mrozikiewicz, A | 1 |
| Banaszkiewicz, W; Mrozikiewicz, A | 1 |
| Persson, G; Siwers, B | 1 |
| Burrows, GD; Sloman, G; Vohra, J | 1 |
| Brignone, A; Genco, S; Puca, FM; Serlenga, L; Specchio, LM | 1 |
| Henry, BW; Overall, JE; Woodward, JA | 1 |
| Huang, CL; Liu, SJ; Waters, IW | 1 |
| Bobkiewicz, T; Chodera, A; Nowakowska, E; Okulicz-Kozaryn, I | 1 |
| Oksenkrug, GF | 1 |
| Maas, JW | 1 |
| Bobkiewicz, T; Chodera, A; Drutel, B; Szpunar, K | 1 |
| Bridges, JW; Dent, JG; Johnson, P | 1 |
| Levy, HB | 1 |
| Field, SL; Murray, M | 1 |
| Ho, IK; McCaslin, PP; Smith, TG; Yu, XZ | 1 |
| Graf, U; van Schaik, N | 1 |
| Ackerman, SH; Banay-Schwartz, M; Russ, MJ; Shindledecker, RD; Smith, GP | 1 |
| Kantor, SJ | 1 |
| Stein, MB; Uhde, TW | 1 |
| Batzri, S | 1 |
| Perel, JM; Somogyi, GT | 1 |
| Eckert, ED; Hatsukami, D; Mitchell, JE; Pomeroy, C; Pyle, RL; Zimmerman, R | 1 |
| Richens, A; Tedstone, JE; Tsanaclis, LM; Williams, J; Wilson, JF | 1 |
| Aberg-Wistedt, A; Asberg, M; Bertilsson, L; Mårtensson, B; Montero, D; Wägner, A | 1 |
| Arita, M; Izumi, F; Takara, H; Wada, A | 1 |
| Armour, M; Friedhoff, AJ; Georgotas, A; McCue, RE; Schweitzer, J | 1 |
| Dorey, RC; Preskorn, SH; Widener, PK | 1 |
| Balon, R; Berchou, R; Ortiz, A; Pohl, R; Rainey, JM; Yeragani, VK | 1 |
| Bowden, CL; Brunswick, D; Carl, J; Frazer, A; Hanin, I; Kocsis, JH; Koslow, SH; Robins, E | 1 |
| Domínguez-Gil, A; Fernández de Gatta, MM; García, MJ; Gutierrez, JR; Tamayo, M | 1 |
| Abbiati, GA; Angelico, P; Testa, R | 1 |
| Abbiati, G; Ibba, M; Schiavi, S; Testa, R | 1 |
| Collins, C; Hu, M; Izutsu, A; Jaklitsch, A; Pankey, S; Pirio, M; Singh, P | 1 |
| Ananth, J | 1 |
| Draper, BM; Manoharan, A | 1 |
| Adan, F; Allen, D; Coccaro, EF; Cooper, TB | 1 |
| Fredrickson, ER; Schneider, LS; Severson, JA; Sloane, RB | 1 |
| Berman, CW; McGrath, PJ; Stewart, JW | 1 |
| Bigger, JT; Giardina, EG; Glassman, AH; Roose, SP; Walsh, BT; Woodring, S | 1 |
| Lydiard, RB | 1 |
| Kalin, NH; Wamboldt, MZ; Weiler, SJ | 1 |
| Borenstein, M; Brenner, R; Cooper, TB; Kane, JM; Lieberman, JA; Steinberg, H; Suckow, RF | 1 |
| Bigger, JT; Brem, RF; Giardina, EG; Johnson, LL; Vita, J | 1 |
| Frisk-Holmberg, M; van der Kleijn, E | 1 |
| al-Sarraj, S; Beckett, AH | 1 |
| De Leenheer, A; Heyndrickx, A | 1 |
| Tuomisto, J | 1 |
| Coffer, AI; McDowall, RD; Robinson, AE | 1 |
| Coull, DC; Johnston, AW; Skinner, C | 1 |
| Lewis, SA; Oswald, I | 2 |
| Loew, D; Taeschler, M | 1 |
| Zingales, I | 1 |
| König, J; Mlejnkovà, M; Rysànek, K; Spànkovà, H | 1 |
| Mlejnkova, M; Rysánek, K; Spánkova, H; Synek, P | 1 |
| Cater, BR; Chapman, D; Hawes, SM; Saville, J | 1 |
| Mlejnková, M; Spánková, H; Svehla, C | 1 |
| Brittain, RT | 1 |
| Garattini, S; Jori, A; Paglialunga, S | 1 |
| Randrup, A; Scheel-Krüger, J | 1 |
| Otten, U; Zetler, G | 1 |
| Nybäck, H; Schubert, J; Sedvall, G | 1 |
| Sturman, G | 1 |
| Schrold, J | 2 |
| Lapin, IP; Oxenkrug, GF | 1 |
| Fraser, MS; Parkin, JM | 1 |
| Karobath, M | 1 |
| Kümpel, Q; Mlcáková, K; Thomasová, E | 1 |
| Imai, S; Ogura, C; Okuma, T; Uchida, Y; Yogi, H | 1 |
| Benesová, O; Rysánek, K; Spánková, H | 1 |
| Horn, AS; Trace, RC | 1 |
| Christiansen, J; Gram, LF; Overo, KF | 2 |
| Lapin, IP; Oksenkrug, GF | 1 |
| Gripenberg, J | 1 |
| Forsythe, WI; Merrett, JD; Redmond, A | 1 |
| Bonaccorsi, A; Garattini, S; Jori, A; Samanin, R | 1 |
| Chapman, B; Feldman, JM | 1 |
| Asberg, M | 1 |
| Berner, P; Kryspin-Exner, K; Poeldinger, W | 1 |
| Fung, HL; Ow, YH | 1 |
| O'Malley, K; Sawyer, PR; Stevenson, IH | 1 |
| König, J; Mlejnková, M; Rysánek, K; Spánková, H; Synek, P | 1 |
| Gaut, ZN | 1 |
| Gaffney, T; Gard, H; Hanenson, I; Knapp, D; Walle, T | 2 |
| Connor, JD; Crawford, IL; Pardridge, WM | 1 |
| Barker, GA; Brown, TC; Dunlop, ME; Loughnan, PM | 1 |
| Boulu, R; Dupeyron, JP; Rossignol, P | 1 |
| Browning, M; O'Malley, K; Stevenson, I; Turnbull, MJ | 1 |
| Dandiya, PC; Kulkarni, SK | 1 |
| Mattila, MJ; Saarnivaara, L | 1 |
| Hall, P | 1 |
| Furlong, FW; Luby, ED | 1 |
| Hills, NF; Milner, G | 1 |
| Forsythe, WI; Merrett, JD | 1 |
| Deza, PC; Marjerrison, G; Silzer, JC | 1 |
| Holt, NF; Kessell, A; Pearce, TA | 1 |
| Gram, LF; Overo, KF | 1 |
| Borg, KO; Lagerström, PO; Westerlund, D | 1 |
| Montanini, R | 1 |
| Maickel, RP; Sokol, GH | 1 |
| Attree, T; Sawyer, P; Turnbull, MJ | 1 |
| Korman, MG; Mushin, G; Sedal, L; Williams, PO | 1 |
| Webb, WL | 1 |
| Orrenius, S; Sjöqvist, F; von Bahr, C | 1 |
| Gram, LF | 3 |
| Oates, JA; Shand, DG | 1 |
| Appel, P; Eckel, K; Harrer, G | 1 |
| Hrbek, J; Navrátil, J | 1 |
| Ahonen, A; Pentilä, A | 1 |
| Bodi, T; Dykyj, R; Mapp, Y; Nodine, JH; Siegler, PE | 1 |
| Azarnoff, DL; Borgå, O; Forshell, GP; Sjöqvist, F | 1 |
| Rohte, O | 3 |
| Renyi, AL; Ross, SB | 1 |
| Dodge, GA; Logue, MA; Schildkraut, JJ | 1 |
| Scanlon, FJ | 1 |
| Gross, R; Linker, H; Reuter, H | 1 |
| Greeff, K; Wagner, J | 2 |
| Opitz, K; Schniedermann, W | 1 |
| Eckhardt, SB; Hite, G; Maxwell, RA | 1 |
| Paceltová, L; Sedivec, V; Valenová, Z | 1 |
| Núnek, K | 1 |
| Ose, E | 1 |
| Horioka, T; Kaneko, H; Masuda, Y; Murai, K; Nakamura, H | 1 |
| Voelkel, A | 1 |
| Kaeser, HE | 1 |
| Feighner, J; Robins, E; Schuckit, M | 1 |
| Avni, J; Edelstein, EL; Khazan, N; Sulman, FG | 1 |
| Corsico, N; Martelli, EA; Segre, AD; Tóth, E | 1 |
| Borchert, U; Opitz, K | 2 |
| Teien, A | 1 |
| Ashford, A; Ross, JW | 1 |
| Ahtee, L; Paasonen, MK | 1 |
| Andrási, F; Borsy, J | 1 |
| Milner, G | 1 |
| Cowell, P | 1 |
| Henderson, JK; Redman, CE; Stark, P; Turk, JA | 1 |
| Serry, D; Serry, M | 1 |
| Chaplin, E; Eckhardt, SB; Keenan, PD; Maxwell, RA; Roth, B | 1 |
| Beattie, RR; Freeman, JW; Mundy, GR; Ryan, C | 1 |
| Capitanucci, P; Fioretti, MC | 1 |
| Ferreira, TA; Mendes, JF | 1 |
| Angel, C; Roberts, AJ | 1 |
| Rasmussen, J | 1 |
| Angst, J; Poeldinger, W | 1 |
| Schmitt, H | 1 |
| Hammer, W; Sjöqvist, F | 1 |
| Ropert, R; Sivadon, P | 1 |
| Bergès, J; Ropert, R | 1 |
| Schechter, MD | 1 |
| Bianchetti, G; Dugas, M; Morselli, PL | 1 |
| Boyer, WF; Friedel, RO | 1 |
| Berken, GH; Stern, WC; Weinstein, DO | 1 |
| Aronstam, RS | 1 |
| Bruno, RL; Glassman, AH; Roose, SP; Siris, SG; Walsh, BT; Wright, LB | 1 |
| Gram, LF; Kragh-Sørensen, P; Kristensen, CB; Møller, M; Pedersen, OL; Thayssen, P | 1 |
| Cutler, NR; Narang, PK | 1 |
| Audus, KL; Gordon, MA | 1 |
| Biegon, A | 1 |
| Orsulak, PJ; Sink, M; Weed, J | 1 |
| Itoh, M; Nakao, H; Notomi, A; Yufu, N | 1 |
| Hrdina, PD | 1 |
| Beierle, FA; Hubbard, RW | 1 |
| Henauer, SA; Hollister, LE | 1 |
| Gold, MS; Pottash, AC | 1 |
| Bjerre, M; Gram, LF; Kragh-Sørensen, P; Kristensen, CB; Møller, M; Petersen, OL; Thayssen, P | 1 |
| Bjerre, M; Gram, LF; Kragh-Sørensen, P; Kristensen, CB; Møller, M; Pedersen, OL; Thayssen, P | 1 |
| Asnis, GM; Endicott, J; Halbreich, U; Nathan, RS; Novacenko, H; Ostrow, L; Sachar, EJ | 1 |
| Vinet, B | 1 |
| Briley, MS; Langer, SZ; Sette, M | 1 |
| Adler, L; Angrist, B; Lautin, A; Rotrosen, J | 1 |
| Bagri, S; Fawcett, J; Javaid, JI; Sabelli, HC | 1 |
| Amsterdam, J; Brunswick, D; Mendels, J | 1 |
| Kragh-Sørensen, P | 1 |
| Montgomery, SA | 1 |
| Alexopoulos, GS; Shamoian, CA | 1 |
| Mendlewicz, J; Razavi, D | 1 |
| Lyskowksi, J; Nasrallah, HA; Schroeder, D | 1 |
| Keller, JM; Kwong, TC; Martinez, R | 1 |
| Cullen, K; Glassman, AH; Roose, SP; Walsh, BT | 1 |
| Friedel, RO | 1 |
| Ettigi, P; Friedel, RO; Joseph, A; Narasimhachari, N; Saady, JJ | 1 |
| Kabra, PM; Mar, NA; Marton, LJ | 1 |
| Bannister, SJ; Dolan, JW; Snyder, LR; van der Wal, S | 1 |
| Bowers, LD; Breutzmann, DA | 1 |
| Reed, K | 1 |
| Bazán, E; Fuentes, JA; Galindo, A; Guillamón, A; Somoza, E; Valencia, A | 1 |
| Dixon, R; Marin, D | 1 |
| Chinn, DM; Crouch, DJ; Jennison, TA; Peat, MA; Thatcher, GW | 1 |
| Jones, S; Turner, P | 1 |
| Cosbey, SH; Craig, I; Gill, R | 1 |
| Alderton, HR | 1 |
| Abel, EL | 1 |
| Arndt, S; Perry, PJ; Zeilmann, C | 1 |
| Coutts, RT | 1 |
| el-Yazigi, A; Raines, DA | 1 |
| Wahba, WW; Winek, CL; Zaveri, NR | 1 |
| De Meester, I; Desnyder, R; Maes, M; Meltzer, HY; Ranjan, R; Scharpe, S | 1 |
| Baba, A; Hori, T; Kurita, H; Piletz, JE; Sasaki, M; Shiraishi, H; Suzuki, T | 1 |
| Roesler, TA; Wamboldt, MZ; Yancey, AG | 1 |
| Blomgren, B; Dahlin, KL; Lâstbom, L; Ryrfeldt, A | 1 |
| Ebihara, I; Koide, H; Nakamura, T; Shimada, N | 1 |
| Ahn, DK; Kim, YS; Park, JS | 1 |
| Guardiola, A; Pereira, KR; Rotta, NT; Terra, AR | 1 |
| Ballesta, J; de la Torre, R; González, S; Ortuño, J; Pascual, JA | 1 |
| Holterman, K; Ohshima, T; Pounder, DJ; Takayasu, T | 1 |
| Cerniglia, CE; Dovichi, NJ; Hansen, EB; Li, XF; Liu, CS; Roos, P | 1 |
| Meyers, BS | 1 |
| Bohlin, K; Cotgreave, IA; Dahlin, KL; Ryrfeldt, A; Strindlund, J | 1 |
| Bolanos, S; Bytautiene, E; Fulep, E; Garfield, RE; Saade, GR; Vedernikov, Y | 1 |
| Taylor, MA | 1 |
| Hatsuda, S; Hayashi, T; Kimura, H; Matsubara, M; Miura, K; Mori, T; Murakami, H; Ohara, M; Ohta, T; Sugita, S; Suzuki, S; Terashima, M | 1 |
| Hayashida, M; Jinno, K; Kawazoe, M; Saito, Y; Takeichi, T | 1 |
| Araújo, GM; Batista e Silva, CM; Hassón-Voloch, A; Louro, SR; Nery da Matta, A; Nunes-Tavares, N | 1 |
| RAVN, J | 1 |
| HORDERN, A | 1 |
| POLLITT, J | 1 |
| HOVE, H | 1 |
| METYS, J; METYSOVA, J; VOTAVA, Z | 1 |
| METYS, J; METYSOVA, J | 1 |
| Amitai, Y; Frischer, H | 2 |
| Banaschewski, T; Heise, CA; Himpel, S; Rothenberger, A | 1 |
| Cantú, MD; Carrilho, E; Lacerda, CA; Lanças, FM; Queiroz, ME; Toso, DR | 1 |
| Guo, B; He, MM; Li, C; Liu, H; Shen, H; Wang, L; Wrighton, SA | 1 |
| Alves, C; Fernandes, C; Lanças, FM; Rodrigues, JC; Santos-Neto, AJ | 1 |
| Nałecz-Jawecki, G | 1 |
| Fulda, S; Himmerich, H; Plümäkers, B; Rink, L; Sheldrick, AJ | 1 |
| Furutani, K; Inanobe, A; Kurachi, Y; Ohno, Y; Yamakawa, Y | 1 |
| Atayee, RS; Best, BM; Bordson, SJ; Ma, JD | 1 |
| Berm, EJJ; Brummel-Mulder, E; Hak, E; Maring, JG; Paardekooper, J; Wilffert, B | 1 |
| Breaud, AR; Clarke, WA; Crutchfield, CA | 1 |
| Cipriani, A; Coghill, D; Cohen, D; Cuijpers, P; Del Giovane, C; Hazell, P; Hetrick, SE; Leucht, S; Liu, L; Liu, Y; Michael, KD; Pu, J; Qin, B; Ravindran, AV; Whittington, C; Xie, P; Yang, L; Zhang, Y; Zhou, X | 1 |
| Caldara, M; Marmiroli, N | 1 |
| Augusti, R; Nascentes, CC; Oliveira, FM; Scheel, GL; Tarley, CRT | 1 |
| Aree, T | 1 |
| Haastrup, MB; Holgersen, NK; Lundstrøm, NH | 1 |
| Giles, R; Girard, MFC; Hopfgartner, G; Knight, P | 1 |
| Yamini, Y; Zamani, R | 1 |
30 review(s) available for imipramine and nortriptyline
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Correlation between plasma concentration and clinical effect of neuroleptics and antidepressants].
Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Fluphenazine; Humans; Imipramine; Nortriptyline; Perazine; Phenelzine; Thioridazine | 1976 |
Tricyclic antidepressants (first of two parts).
Topics: Aged; Amines; Amitriptyline; Antidepressive Agents, Tricyclic; Chemical Phenomena; Chemistry; Child; Depression; Desipramine; Doxepin; Humans; Imipramine; Kinetics; Neurotransmitter Agents; Nortriptyline; Protriptyline | 1978 |
Uropharmacology: X. Central nervous system stimulants and depressants.
Topics: Amphetamines; Anesthetics; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Baclofen; Benzodiazepines; Central Nervous System Agents; Chloral Hydrate; Humans; Imipramine; Levodopa; Meperidine; Meprobamate; Morphine; Nortriptyline; Paraldehyde; Phenothiazines; Phenytoin; Picrotoxin; Reserpine; Strychnine; Urinary Tract | 1979 |
Poisoning by tricyclic antidepressant drugs: general and pharmacokinetic considerations.
Topics: Accidents, Home; Adolescent; Adult; Aged; Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Brain Chemistry; Child; Child, Preschool; Desipramine; Dibenzazepines; Drug Interactions; Female; Humans; Imipramine; Infant; Intestinal Absorption; Kinetics; Liver; Lung; Male; Mice; Middle Aged; Nortriptyline; Opipramol; Poisoning; Protein Binding; Rats; Suicide | 1975 |
Blood levels of tricyclic antidepressant drugs: assay procedures, reproducibility and relationship to therapeutic outcome and side effects.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Interactions; Female; Humans; Imipramine; Kinetics; Nortriptyline; Protein Binding; Protriptyline | 1977 |
[Psychopharmacogentics].
Topics: Adult; Animals; Antidepressive Agents, Tricyclic; Asian People; Dose-Response Relationship, Drug; Drug Hypersensitivity; Ethanol; Female; Guinea Pigs; Horses; Humans; Imipramine; Isoniazid; Male; Middle Aged; Monoamine Oxidase Inhibitors; Nortriptyline; Pharmacogenetics; Polymorphism, Genetic; Pregnancy; Psychotropic Drugs; Racial Groups; Rats; Species Specificity; Swine; Twins; White People | 1976 |
Clomipramine: an antiobsessive drug.
Topics: Anxiety; Behavior Therapy; Clinical Trials as Topic; Clomipramine; Compulsive Behavior; Depressive Disorder; Diazepam; Haloperidol; Humans; Imipramine; Nortriptyline; Obsessive Behavior; Obsessive-Compulsive Disorder; Phobic Disorders; Psychological Tests | 1986 |
Tricyclic antidepressants--blood level measurements and clinical outcome: an APA Task Force report. Task Force on the Use of Laboratory Tests in Psychiatry.
Topics: Antidepressive Agents, Tricyclic; Blood Chemical Analysis; Clinical Trials as Topic; Depressive Disorder; Desipramine; Hospitalization; Humans; Imipramine; Laboratories; Nortriptyline; Outcome and Process Assessment, Health Care; Research Design | 1985 |
Tricyclic-resistant depression: treatment resistance or inadequate treatment?
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Humans; Imipramine; Intestinal Absorption; Kinetics; Nortriptyline; Patient Compliance | 1985 |
[Monoamines and the pharmacological effects of tricyclic antidepressive agents].
Topics: Amitriptyline; Antidepressive Agents; Brain; Brain Chemistry; Central Nervous System; Chemical Phenomena; Chemistry; Desipramine; Humans; Hydroxyindoleacetic Acid; Imipramine; Methyltransferases; Monoamine Oxidase; Norepinephrine; Nortriptyline; Receptors, Drug; Serotonin | 1972 |
Individualization of treatment with tricyclic compounds.
Topics: Animals; Antidepressive Agents; Chromatography, Gas; Clomipramine; Depression; Drug Interactions; Electrocardiography; Humans; Imipramine; Kinetics; Norepinephrine; Nortriptyline; Rats; Serotonin; Time Factors | 1974 |
Antidepressant and antipsychotic plasma levels.
Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Chromatography; Dose-Response Relationship, Drug; Humans; Imipramine; Monitoring, Physiologic; Nortriptyline | 1984 |
Plasma level monitoring of antidepressants: theoretical basis and clinical application.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Genetic Variation; Humans; Imipramine; Kinetics; Nortriptyline; Oxidation-Reduction; Patient Compliance; Pharmacogenetics | 1984 |
Implications of dosing tricyclic antidepressants and benzodiazepines in geriatrics.
Topics: Adipose Tissue; Adult; Aged; Aging; Amitriptyline; Antidepressive Agents, Tricyclic; Anxiety Disorders; Benzodiazepines; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Gastric Mucosa; Glomerular Filtration Rate; Humans; Imipramine; Kinetics; Middle Aged; Nordazepam; Nortriptyline | 1984 |
The clinical application of tricyclic antidepressant pharmacokinetics and plasma levels.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Desipramine; Doxepin; Heart; Humans; Imipramine; Nortriptyline; Protriptyline | 1980 |
The use of clinical kinetic data in treatment with antidepressant drugs.
Topics: Adult; Affective Symptoms; Aged; Drug Therapy, Combination; Female; Humans; Imipramine; Kinetics; Male; Middle Aged; Nortriptyline; Perphenazine | 1980 |
Pharmacokinetics and clinical response to tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depression; Humans; Imipramine; Kinetics; Nortriptyline | 1980 |
Measurement of serum drug levels in the assessment of antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Depression; Humans; Imipramine; Nortriptyline | 1980 |
Tricyclic medication in children and the QT interval: case report and discussion.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Child; Contraindications; Desipramine; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrocardiography; Electrocardiography, Ambulatory; Exercise Test; Female; Humans; Imipramine; Long QT Syndrome; Nortriptyline; Practice Guidelines as Topic | 1995 |
Tricyclic antidepressant concentrations in plasma: an estimate of their sensitivity and specificity as a predictor of response.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline; ROC Curve; Sensitivity and Specificity | 1994 |
Polymorphism in the metabolism of drugs, including antidepressant drugs: comments on phenotyping.
Topics: Clomipramine; Cytochromes; Dealkylation; Depressive Disorder; Desipramine; Dextromethorphan; Drug Interactions; Female; Humans; Hydroxylation; Imipramine; Isoenzymes; Male; Mephenytoin; Nortriptyline; Phenotype; Polymorphism, Genetic | 1994 |
Cardiovascular effects of tricyclic antidepressants in childhood asthma: a case series and review.
Topics: Adolescent; Anti-Inflammatory Agents; Antidepressive Agents, Tricyclic; Anxiety Disorders; Asthma; Blood Pressure; Bronchodilator Agents; Cardiovascular System; Child; Depressive Disorder; Desipramine; Electrocardiography; Female; Heart Rate; Humans; Imipramine; Male; Nortriptyline; Treatment Outcome | 1997 |
Depression and dementia: comorbidities, identification, and treatment.
Topics: Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Benzamides; Citalopram; Clomipramine; Cognition Disorders; Comorbidity; Dementia; Depression; Female; Fluoxetine; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Neuropsychological Tests; Nortriptyline; Selective Serotonin Reuptake Inhibitors; Sertraline | 1998 |
THE ANTIDEPRESSANT DRUGS.
Topics: Amitriptyline; Antidepressive Agents; Central Nervous System Stimulants; Depression; Depressive Disorder; Desipramine; Drug Therapy; Epidemiology; Humans; Imipramine; Mental Disorders; Monoamine Oxidase Inhibitors; Nortriptyline; Phenelzine; Psychopharmacology | 1965 |
The safety of non-stimulant agents for the treatment of attention-deficit hyperactivity disorder.
Topics: Adrenergic alpha-Agonists; Adult; Antidepressive Agents, Tricyclic; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Bupropion; Child; Clonidine; Desipramine; Guanfacine; Humans; Imipramine; Nortriptyline; Propylamines | 2005 |
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.
Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Confounding Factors, Epidemiologic; Depressive Disorder, Major; Desipramine; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Evidence-Based Medicine; Fluoxetine; Humans; Imipramine; Mianserin; Mirtazapine; Nortriptyline; Paroxetine; Piperazines; Randomized Controlled Trials as Topic; Research Design; Sertraline; Treatment Outcome; Triazoles; Venlafaxine Hydrochloride | 2016 |
The effect of smoking on the plasma concentration of tricyclic antidepressants: a systematic review.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Imipramine; Nortriptyline; Smoking | 2022 |
25 trial(s) available for imipramine and nortriptyline
| Article | Year |
|---|---|
Blood levels of tricyclic antidepressant drugs: assay procedures, reproducibility and relationship to therapeutic outcome and side effects.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Interactions; Female; Humans; Imipramine; Kinetics; Nortriptyline; Protein Binding; Protriptyline | 1977 |
Plasma and erythrocyte levels of tricyclic antidepressants in depressed patients.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Biopharmaceutics; Clinical Trials as Topic; Depression; Desipramine; Doxepin; Erythrocytes; Humans; Imipramine; Middle Aged; Nortriptyline | 1978 |
The effect of tricyclic antidepressant compounds on patients with passive-dependent personality traits.
Topics: Adult; Antidepressive Agents, Tricyclic; Body Weight; Clinical Trials as Topic; Dependency, Psychological; Female; Humans; Imipramine; Male; Middle Aged; MMPI; Nortriptyline; Personality; Personality Inventory; Surveys and Questionnaires | 1976 |
Plasma tryptophan to large neutral amino acid ratios in depressed and normal subjects.
Topics: Adolescent; Adult; Amino Acids; Blood-Brain Barrier; Depressive Disorder; Desipramine; Double-Blind Method; Eating; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Tryptophan | 1990 |
Imipramine equivalents.
Topics: Antidepressive Agents; Clinical Trials as Topic; Humans; Imipramine; Nortriptyline; Research Design; Terminology as Topic | 1990 |
Triiodothyronine potentiation of tricyclic antidepressant treatment in patients with panic disorder.
Topics: Adult; Anxiety Disorders; Arousal; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imipramine; Male; Nortriptyline; Panic; Pilot Projects; Single-Blind Method; Triiodothyronine | 1990 |
Response to alternative antidepressants in imipramine nonresponders with bulimia nervosa.
Topics: Adolescent; Adult; Antidepressive Agents; Bulimia; Clinical Trials as Topic; Desipramine; Feeding Behavior; Female; Fluoxetine; Humans; Imipramine; Monoamine Oxidase Inhibitors; Nortriptyline; Random Allocation | 1989 |
Effects of antidepressant treatments on platelet tritiated imipramine binding in major depressive disorder.
Topics: Adult; Aged; Alanine; Antidepressive Agents; Blood Platelets; Carrier Proteins; Depressive Disorder; Electroconvulsive Therapy; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Outcome and Process Assessment, Health Care; Psychiatric Status Rating Scales; Receptors, Drug; Receptors, Neurotransmitter; Receptors, Serotonin; Zimeldine | 1987 |
Clinical and treatment effects on 3H-clonidine and 3H-imipramine binding in elderly depressed patients.
Topics: Blood Platelets; Carrier Proteins; Clonidine; Depressive Disorder; Double-Blind Method; Humans; Imidazoline Receptors; Imipramine; Kinetics; Middle Aged; Nortriptyline; Phenelzine; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-2; Receptors, Drug; Receptors, Neurotransmitter | 1987 |
Sodium lactate infusions after treatment with tricyclic antidepressants: behavioral and physiological findings.
Topics: Antidepressive Agents, Tricyclic; Arousal; Clinical Trials as Topic; Desipramine; Double-Blind Method; Doxepin; Fear; Humans; Imipramine; Isoproterenol; Lactates; Lactic Acid; Nortriptyline; Panic; Psychological Tests | 1988 |
Clomipramine: an antiobsessive drug.
Topics: Anxiety; Behavior Therapy; Clinical Trials as Topic; Clomipramine; Compulsive Behavior; Depressive Disorder; Diazepam; Haloperidol; Humans; Imipramine; Nortriptyline; Obsessive Behavior; Obsessive-Compulsive Disorder; Phobic Disorders; Psychological Tests | 1986 |
Tricyclic antidepressants--blood level measurements and clinical outcome: an APA Task Force report. Task Force on the Use of Laboratory Tests in Psychiatry.
Topics: Antidepressive Agents, Tricyclic; Blood Chemical Analysis; Clinical Trials as Topic; Depressive Disorder; Desipramine; Hospitalization; Humans; Imipramine; Laboratories; Nortriptyline; Outcome and Process Assessment, Health Care; Research Design | 1985 |
Enuresis and psychoactive drugs.
Topics: Adolescent; Amitriptyline; Child; Child, Preschool; Chlordiazepoxide; Clinical Trials as Topic; Dibenzazepines; Enuresis; Female; Humans; Imipramine; Male; Nortriptyline; Placebos | 1972 |
Therapy possibilities for therapy-resistant depressions.
Topics: Amitriptyline; Antidepressive Agents; Chronic Disease; Clinical Trials as Topic; Depression; Desipramine; Drug Resistance; Drug Therapy, Combination; Electroconvulsive Therapy; Humans; Imipramine; Nortriptyline; Remission, Spontaneous; Time Factors; Tranquilizing Agents | 1974 |
Lithium in the control of mania.
Topics: Adult; Amitriptyline; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Desipramine; Female; Humans; Imipramine; Lithium; Male; Middle Aged; Nortriptyline; Thioridazine; Tranylcypromine; Trifluoperazine | 1967 |
A double-blind assessment of antidepressants in the treatment of 212 enuretic patients.
Topics: Clinical Trials as Topic; Desipramine; Enuresis; Epilepsy; Female; Humans; Humidity; Imipramine; Male; Mental Disorders; Nortriptyline; Sex Factors; Temperature | 1968 |
A controlled trial of imipramine ('Tofranil') and nortriptyline ('Allegron') in the treatment of enuresis.
Topics: Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Enuresis; Female; Humans; Imipramine; Male; Nortriptyline | 1969 |
Verbal behaviour changes with depression treatment.
Topics: Adolescent; Adult; Amitriptyline; Analysis of Variance; Antidepressive Agents; Clinical Trials as Topic; Depression; Desipramine; Female; Humans; Imipramine; Interpersonal Relations; Interview, Psychological; Male; Middle Aged; Nortriptyline; Placebos; Psychiatric Status Rating Scales; Self Concept; Verbal Behavior | 1969 |
A controlled study of nortriptyline and imipramine.
Topics: Anxiety; Body Weight; Clinical Trials as Topic; Depression; Female; Humans; Imipramine; Nortriptyline; Psychiatric Status Rating Scales; Sleep Initiation and Maintenance Disorders; Socioeconomic Factors; Time Factors | 1970 |
A variable dose phase 3, human bioassay of nortriptyline.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Desipramine; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline | 1965 |
[Comparative clinical trial of nortriptyline in the treatment of depressive states].
Topics: Adult; Antidepressive Agents; Female; Humans; Imipramine; Male; Mental Disorders; Nortriptyline | 1966 |
Cardiovascular effect of imipramine and nortriptyline in elderly patients.
Topics: Aged; Blood Pressure; Electrocardiography; Female; Hemodynamics; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Placebos; Time Factors | 1981 |
Dose-dependent kinetics of imipramine in elderly patients.
Topics: Aged; Depressive Disorder; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Kinetics; Male; Nortriptyline; Psychiatric Status Rating Scales | 1981 |
Pharmacokinetics and clinical response to tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depression; Humans; Imipramine; Kinetics; Nortriptyline | 1980 |
[Use of drugs in attention deficit hyperactivity disorders].
Topics: Analysis of Variance; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Electroencephalography; Female; Humans; Imipramine; Male; Methylphenidate; Neurologic Examination; Nortriptyline | 1997 |
266 other study(ies) available for imipramine and nortriptyline
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
2,4-Dihydro-3H-1,2,4-triazole-3-thiones as potential antidepressant agents.
Topics: Animals; Antidepressive Agents; Desipramine; gamma-Aminobutyric Acid; Male; Mice; Monoamine Oxidase Inhibitors; Norepinephrine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Triazoles | 1988 |
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship | 1981 |
Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography.
Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Enzyme Inhibitors; Histamine H1 Antagonists; Micelles; Models, Biological; Norepinephrine; Rats; Receptors, Adrenergic, alpha-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Structure-Activity Relationship | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Electrophysiology; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Proteins; Heart; Humans; Myocardium; Oocytes; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; RNA, Messenger; Xenopus laevis | 2004 |
LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake.
Topics: Amino Acid Sequence; Animals; Antidepressive Agents, Tricyclic; Bacterial Proteins; Binding Sites; Caenorhabditis elegans Proteins; Cell Line; Conserved Sequence; Crystallography, X-Ray; Desipramine; Dopamine; Dopamine Uptake Inhibitors; Drosophila Proteins; Humans; Leucine; Models, Molecular; Molecular Sequence Data; Neurotransmitter Uptake Inhibitors; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Plasma Membrane Neurotransmitter Transport Proteins; Protein Binding; Protein Conformation; Selective Serotonin Reuptake Inhibitors; Sequence Homology, Amino Acid; Serotonin | 2007 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Which metabolites circulate?
Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain.
Topics: | 2022 |
Tricyclic antidepressants and histamine H1 receptors.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Atropine; Benztropine; Cells, Cultured; Clozapine; Cyproheptadine; Desipramine; Doxepin; Haloperidol; Histamine H1 Antagonists; Hydroxyzine; Imipramine; Mice; Neoplasms, Experimental; Neuroblastoma; Nortriptyline; Protriptyline; Receptors, Histamine; Receptors, Histamine H1; Receptors, Muscarinic | 1979 |
Radioimmunoassay for nortriptyline and amitriptyline.
Topics: Amitriptyline; Humans; Imipramine; Nortriptyline; Radioimmunoassay; Tritium | 1977 |
Interactions of tricyclic antidepressant drugs with deprivation-induced fluid consumption by rats.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Doxepin; Drinking Behavior; Fenclonine; Imipramine; Male; Methyltyrosines; Nortriptyline; Protriptyline; Rats; Water Deprivation | 1977 |
The role of plasma level monitoring of tricyclic antidepressant drugs as an aid to treatment.
Topics: Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline | 1979 |
Relationship between surface activity and toxicity to Chang liver cultures of tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Cells, Cultured; Clomipramine; Doxepin; Glucuronidase; Humans; Imipramine; L-Lactate Dehydrogenase; Liver; Nortriptyline; Surface Tension | 1979 |
Cardiovascular side effects of long-term therapy with tricyclic antidepressants in the aged.
Topics: Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovascular System; Electrocardiography; Female; Heart Block; Heart Failure; Humans; Imipramine; Male; Myocardial Infarction; Nortriptyline; Thiothixene | 1979 |
Monitoring tricyclic antidepressant plasma concentrations.
Topics: Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Humans; Imipramine; Nortriptyline | 1979 |
The effects of antihistamines in a modified behavioral despair test.
Topics: Amitriptyline; Animals; Behavior, Animal; Histamine Antagonists; Imipramine; Immersion; Male; Mice; Motor Activity; Nortriptyline | 1979 |
Guidelines for clinical use in interpreting tricyclic plasma levels.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Dose-Response Relationship, Drug; Humans; Imipramine; Maprotiline; Nortriptyline | 1979 |
The effect of tricyclic antidepressants (TA) on the circulatory system in primary arterial hypertension.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Catecholamines; Hemodynamics; Humans; Hypertension; Imipramine; Nortriptyline | 1979 |
Radioimmunoassay of amitriptyline and nortriptyline in body fluids.
Topics: Amitriptyline; Animals; Cross Reactions; Humans; Imipramine; Nortriptyline; Radioimmunoassay; Saliva; Sheep | 1978 |
Tricyclic antidepressant overdose: incidence of symptoms.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Doxepin; Electrocardiography; Heart; Humans; Imipramine; Nortriptyline | 1977 |
Liquid-chromatographic procedure for tricyclic drugs and their metabolites in plasma.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Desipramine; Humans; Imipramine; Nortriptyline | 1978 |
Determination of drugs in plasma by high-performance thin-layer chromatography.
Topics: Amitriptyline; Chlorpromazine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Desipramine; Humans; Imipramine; Nortriptyline; Phenobarbital; Phenytoin; Psychotropic Drugs; Spectrophotometry, Ultraviolet | 1978 |
Tricyclic antidepressants: plasma levels and clinical findings in overdose.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Electrocardiography; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline | 1978 |
High-performance liquid-chromatographic simultaneous determination of commonly used tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline | 1978 |
[Blood levels of tricyclics and evolution of depressive syndrome during therapy].
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Humans; Imipramine; Nortriptyline | 1978 |
Tricyclic antidepressants and cardiac conduction: changes in ventricular automaticity.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Blood Pressure; Dogs; Female; Heart Atria; Heart Conduction System; Heart Rate; Heart Ventricles; Imipramine; Male; Nitroglycerin; Nortriptyline | 1976 |
Comparison of single dose kinetics of imipramine, nortriptyline and antipyrine in man.
Topics: Administration, Oral; Adult; Antipyrine; Female; Half-Life; Humans; Imipramine; Infusions, Parenteral; Kinetics; Liver Circulation; Male; Models, Biological; Nortriptyline | 1976 |
Assay of tricyclic structured drugs and their metabolites in urine by high-performance liquid chromatography.
Topics: Amitriptyline; Chlorpromazine; Chromatography, High Pressure Liquid; Dibenzocycloheptenes; Humans; Imipramine; Nortriptyline; Protriptyline | 1977 |
Relationship between age and tricyclic antidepressant plasma levels.
Topics: Administration, Oral; Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Body Weight; Depression; Desipramine; Female; Half-Life; Heart; Humans; Imipramine; Male; Middle Aged; Nortriptyline | 1977 |
Tricyclic antidepressants as antimuscarinic drugs: in vivo and in vitro studies.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Body Temperature; Brain; Cholinesterase Inhibitors; Imipramine; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Nortriptyline; Parasympatholytics; Pupil; Receptors, Muscarinic; Scopolamine; Time Factors; Tremor | 1977 |
High-performance thin-layer chromatographic determination of psychopharmacologic agents in blood serum.
Topics: Amitriptyline; Chlorpromazine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Desipramine; Humans; Imipramine; Methods; Nortriptyline; Psychotropic Drugs; Spectrophotometry, Ultraviolet | 1977 |
Effect of flupenthixol on depression with special reference to combination use with tricyclic antidepressants. An uncontrolled pilot study with 45 patients.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Clomipramine; Depression; Drug Evaluation; Drug Therapy, Combination; Female; Flupenthixol; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Pilot Projects; Thioxanthenes; Trimipramine | 1976 |
Measurement of plasma levels of tricylic psychoactive drugs and their metabolites by UV reflectance photometry of thin layer chromatograms.
Topics: Amitriptyline; Chromatography, Thin Layer; Clozapine; Desipramine; Humans; Imipramine; Methods; Nortriptyline; Perazine; Psychotropic Drugs; Spectrophotometry, Ultraviolet | 1976 |
Cardiac effects of different tricyclic antidepressant drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Bundle of His; Doxepin; Electrocardiography; Heart Conduction System; Heart Rate; Humans; Imipramine; Nortriptyline; Substance-Related Disorders | 1976 |
The separation of some tricyclic antidepressants by high-performance liquid chromatography.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Desipramine; Imipramine; Microchemistry; Nortriptyline; Protriptyline; Trimipramine | 1976 |
The influence of some antidepressant drugs on cardiac function. III. Influence on the isolated heart and isolated coronary blood vessels.
Topics: Amitriptyline; Animals; Cats; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Heart; Imipramine; Myocardial Contraction; Nortriptyline | 1976 |
The influence of some antidepressant drugs on cardiac function. IV. Influence of blood supply of the heart in situ.
Topics: Amitriptyline; Animals; Cats; Coronary Circulation; Dose-Response Relationship, Drug; Female; Heart; Heart Rate; Imipramine; Male; Myocardial Contraction; Nortriptyline | 1976 |
The risk of potentiating effect of local anaesthesia with adrenalin in patients treated with tricyclic antidepressants.
Topics: Adult; Aged; Amitriptyline; Anesthesia, Local; Blood Pressure; Drug Interactions; Epinephrine; Female; Humans; Imipramine; Lidocaine; Male; Membranes; Middle Aged; Nortriptyline; Pulse; Time Factors | 1975 |
Assessment of cardiovascular side effects of therapeutic doses of tricyclic anti-depressant drugs.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Blood Pressure; Depression, Chemical; Doxepin; Electrocardiography; Female; Heart Conduction System; Heart Rate; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Physical Exertion; Stimulation, Chemical | 1975 |
[Modifications induced by antidepressant drugs on the vestibulo-ocular reflex in man].
Topics: Amitriptyline; Antidepressive Agents; Eye Movements; Humans; Imipramine; Nortriptyline; Phenelzine; Reflex; Reflex, Oculocardiac; Trazodone; Vestibule, Labyrinth | 1975 |
Patterns of symptom change in anxious depressed outpatients treated with different drugs.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Depression; Desipramine; Diazepam; Drug Combinations; Fluphenazine; Humans; Imipramine; Mental Disorders; Nortriptyline; Perphenazine; Thioridazine; Thiothixene; Tranquilizing Agents; Trifluoperazine | 1975 |
Interactions of tricyclic antidepressants and barbiturates in barbiturate-tolerant and nontolerant rats.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Barbiturates; Brain Chemistry; Desipramine; Drug Interactions; Drug Tolerance; Imipramine; Male; Microsomes, Liver; Nortriptyline; Pentobarbital; Rats; Sleep; Time Factors | 1975 |
Influence of tricyclic antidepressant drugs on experimental arterial hypertension.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Female; Hexobarbital; Hypertension; Imipramine; Kidney; Male; Nephrectomy; Nortriptyline; Opipramol; Rats | 1975 |
[Effect of prothixen and related compounds on serotonin absorption by human thrombocytes].
Topics: Absorption; Amitriptyline; Biological Transport; Blood Platelets; Cell Membrane Permeability; Chlorpromazine; Clomipramine; Depression, Chemical; Desipramine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Serotonin; Structure-Activity Relationship; Thioxanthenes; Triazines | 1975 |
Biogenic amines and depression. Biochemical and pharmacological separation of two types of depression.
Topics: Amitriptyline; Biogenic Amines; Depression; Desipramine; Dextroamphetamine; Humans; Hydroxyindoleacetic Acid; Imipramine; Metanephrine; Methoxyhydroxyphenylglycol; Normetanephrine; Nortriptyline; Vanilmandelic Acid | 1975 |
[Postsynaptic attack of tricyclic antidepressive agents in the circulatory system].
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Dose-Response Relationship, Drug; Female; Heart; Hemodynamics; Imipramine; Male; Norepinephrine; Nortriptyline; Opipramol; Rabbits; Rats; Receptors, Drug | 1975 |
The effects of some pharmacologically active amines on the rate of gastric emptying in rats.
Topics: Animals; Depression, Chemical; Desipramine; Dextroamphetamine; Imipramine; Male; Nortriptyline; Parasympatholytics; Rats; Rats, Inbred Strains; Stomach; Structure-Activity Relationship | 1976 |
Minimal brain dysfunction/specific learning disability: a clinical approach for the primary physician.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Dextroamphetamine; Family Practice; Humans; Imipramine; Learning Disabilities; Methylphenidate; Nortriptyline; Primary Health Care; Terminology as Topic | 1976 |
Inhibition and metabolite complexation of rat hepatic microsomal cytochrome P450 by tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Desipramine; Hydroxylation; Imipramine; Male; Microsomes, Liver; Nortriptyline; Rats; Rats, Inbred Strains; Steroid 16-alpha-Hydroxylase; Testosterone | 1992 |
Amitriptyline prevents N-methyl-D-aspartate (NMDA)-induced toxicity, does not prevent NMDA-induced elevations of extracellular glutamate, but augments kainate-induced elevations of glutamate.
Topics: Amitriptyline; Animals; Cell Death; Cells, Cultured; Extracellular Matrix; Glutamates; Imipramine; Kainic Acid; Lethal Dose 50; N-Methylaspartate; Neurons; Nortriptyline; Quisqualic Acid; Rats; Rats, Inbred Strains; Taurine | 1992 |
Genotoxicity evaluation of five tricyclic antidepressants in the wing somatic mutation and recombination test in Drosophila melanogaster.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; DNA; Dose-Response Relationship, Drug; Drosophila melanogaster; Imipramine; Mutagenicity Tests; Nortriptyline; Protriptyline; Recombination, Genetic | 1991 |
Tricyclic antidepressants and acid secretory response of rabbit gastric cells.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Bucladesine; Carbachol; Cyclic AMP; Gastric Acid; Gastric Mucosa; Histamine; Imipramine; Nortriptyline; Oxygen Consumption; Parietal Cells, Gastric; Rabbits; Receptors, Histamine; Time Factors | 1985 |
Antagonism by tricyclic antidepressants of the muscarinic receptors located on the adrenergic nerve endings in rabbit heart atrium.
Topics: Animals; Antidepressive Agents, Tricyclic; Atropine; Desipramine; Electric Stimulation; Heart; Imipramine; Male; Norepinephrine; Nortriptyline; Oxotremorine; Parasympatholytics; Rabbits; Receptors, Muscarinic; Sympathetic Nervous System | 1989 |
External quality assurance of tricyclic antidepressant measurements in serum: eight years of progress?
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Chromatography, High Pressure Liquid; Desipramine; Humans; Imipramine; Nortriptyline; Quality Control | 1989 |
Inhibition of 22Na influx by tricyclic and tetracyclic antidepressants and binding of [3H]imipramine in bovine adrenal medullary cells.
Topics: Adrenal Medulla; Amitriptyline; Animals; Anthracenes; Calcium; Carrier Proteins; Catecholamines; Cattle; Cells, Cultured; Imipramine; Kinetics; Maprotiline; Mianserin; Nortriptyline; Receptors, Drug; Receptors, Neurotransmitter; Sodium; Sodium Radioisotopes; Structure-Activity Relationship; Tritium | 1987 |
Results compared for tricyclic antidepressants as assayed by liquid chromatography and enzyme immunoassay.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Humans; Imipramine; Immunoenzyme Techniques; Nortriptyline | 1988 |
Cerebrospinal fluid levels of amitriptyline, nortriptyline, imipramine and desmethylimipramine. Relationship to plasma levels and treatment outcome.
Topics: Amitriptyline; Bipolar Disorder; Depressive Disorder; Desipramine; Double-Blind Method; Female; Gas Chromatography-Mass Spectrometry; Humans; Imipramine; Male; Nortriptyline; Psychiatric Status Rating Scales | 1985 |
High levels of tricyclic antidepressants in conventional therapy: determinant factors.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline; Risk Factors | 1988 |
Effect of citalopram, amineptine, imipramine and nortriptyline on stress-induced (footshock) analgesia in rats.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Citalopram; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Electroshock; Hindlimb; Imipramine; Male; Nortriptyline; Pain; Propylamines; Rats; Rats, Inbred Strains | 1987 |
Effects of oral administration of nortriptyline, imipramine and citalopram on morphine hot-plate and tail-immersion analgesia in rats.
Topics: Analgesia; Animals; Antidepressive Agents; Citalopram; Drug Interactions; Imipramine; Male; Morphine; Nortriptyline; Propylamines; Rats; Reaction Time | 1987 |
Quantitative homogeneous enzyme immunoassays for amitriptyline, nortriptyline, imipramine, and desipramine.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Cross Reactions; Desipramine; Humans; Imipramine; Immunoenzyme Techniques; Methods; Nortriptyline | 1986 |
Neutropenia with cross-intolerance between two tricyclic antidepressant agents.
Topics: Adult; Agranulocytosis; Cross Reactions; Depression; Female; Humans; Imipramine; Neutropenia; Nortriptyline | 1987 |
Plasma-serum differences in the assessment of tricyclic antidepressant blood levels.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Humans; Imipramine; Nortriptyline; Plasma | 1987 |
3H-imipramine binding in depressed elderly: relationship to family history and clinical response.
Topics: Aged; Blood Platelets; Depressive Disorder; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Psychotherapy; Tritium | 1986 |
Doses and blood levels of tricyclic antidepressants.
Topics: Adult; Depressive Disorder; Drug Administration Schedule; Female; Humans; Imipramine; Middle Aged; Nortriptyline | 1987 |
Tricyclic antidepressants in depressed patients with cardiac conduction disease.
Topics: Antidepressive Agents, Tricyclic; Bundle-Branch Block; Depressive Disorder; Electrocardiography; Female; Heart Block; Heart Conduction System; Humans; Hypotension, Orthostatic; Imipramine; Male; Middle Aged; Nortriptyline; Prospective Studies | 1987 |
Consistent reversal of abnormal DSTs after different antidepressant therapies in a patient with dementia.
Topics: Amitriptyline; Antidepressive Agents; Dementia; Depressive Disorder; Dexamethasone; Humans; Hydrocortisone; Imipramine; Male; Middle Aged; Nortriptyline; Trazodone | 1985 |
Tricyclic antidepressant and metabolite levels in chronic renal failure.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Chromatography, Liquid; Depression; Desipramine; Female; Half-Life; Humans; Imipramine; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Nortriptyline; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis | 1985 |
Effect of imipramine and nortriptyline on left ventricular function and blood pressure in patients treated for arrhythmias.
Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Drug Administration Schedule; Electrocardiography; Female; Heart Ventricles; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Posture; Stroke Volume | 1985 |
The relationship between the lipophilic nature of tricyclic neuroleptics and antidepressants, and histamine release.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Chlorpromazine; Chlorprothixene; Clopenthixol; Desipramine; Fluphenazine; Histamine Release; Imipramine; Kinetics; Male; Mast Cells; Methotrimeprazine; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Rats; Solvents; Structure-Activity Relationship; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1972 |
Metabolism of amitriptyline, nortriptyline, imipramine and desipramine to yield hydroxylamines.
Topics: Amitriptyline; Animals; Chromatography, Gas; Chromatography, Thin Layer; Desipramine; Guinea Pigs; Hydroxylamines; Imipramine; In Vitro Techniques; Mass Spectrometry; Microsomes, Liver; Mitochondria, Liver; Nortriptyline; Rabbits | 1973 |
Identification of phenothiazine derivatives and analogs by x-ray diffraction. II. Active substances in pharmaceutical formulations.
Topics: Amitriptyline; Chlorprothixene; Crystallization; Dibenzazepines; Fluphenazine; Imipramine; Methods; Methotrimeprazine; Nortriptyline; Opipramol; Perphenazine; Phenothiazines; Picrates; Prochlorperazine; Promazine; Promethazine; Quaternary Ammonium Compounds; Thioridazine; Triflupromazine; X-Ray Diffraction | 1971 |
A new modification for studying 5-HT uptake by blood platelets: a re-evaluation of tricyclic antidepressants as uptake inhibitors.
Topics: Amitriptyline; Animals; Blood Platelets; Carbon Radioisotopes; Chlorpromazine; Desipramine; Dibenzazepines; Doxepin; Imipramine; In Vitro Techniques; Kinetics; Models, Biological; Nortriptyline; Promazine; Rabbits; Serotonin; Synaptosomes; Temperature; Trifluoperazine; Triflupromazine | 1974 |
Toxicology of some autopsy cases involving tricyclic antidepressant drugs.
Topics: Adult; Amitriptyline; Antidepressive Agents; Autopsy; Brain Chemistry; Desipramine; Dibenzazepines; Ethanol; Female; Humans; Imipramine; Kidney; Liver; Lung; Male; Middle Aged; Nortriptyline; Protein Binding; Spleen; Stomach | 1974 |
Antagonism of the hypotensive action of bethanidine and debrisoquine by tricyclic antidepressants.
Topics: Adult; Aged; Amidines; Amitriptyline; Antidepressive Agents; Antihypertensive Agents; Blood Pressure; Drug Antagonism; Female; Guanidines; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Quinolines | 1969 |
Overdose of tricyclic antidepressants and REM sleep rebound.
Topics: Amitriptyline; Antidepressive Agents; Dreams; Electroencephalography; Electromyography; Electrooculography; Humans; Imipramine; Nortriptyline; Sleep, REM; Time Factors | 1970 |
[The effect of tricyclic antidepressants on rabbit 5-hydroxytryptophan hyperthermia].
Topics: Animals; Antidepressive Agents; Desipramine; Fever; Imipramine; Nortriptyline; Rabbits; Serotonin; Tryptophan | 1966 |
Systematic identification of psychotropic drugs by thin layer chromatography. II.
Topics: Amitriptyline; Chlorpromazine; Chlorprothixene; Chromatography, Thin Layer; Desipramine; Female; Humans; Imipramine; Male; Meprobamate; Nortriptyline; Phenothiazines; Schizophrenia; Silicon Dioxide; Thioridazine; Tranquilizing Agents | 1968 |
Overdose of tricyclic anti-depressants and deductions concerning their cerebral action.
Topics: Adolescent; Adult; Amitriptyline; Brain; Brain Chemistry; Dreams; Electroencephalography; Female; Humans; Imipramine; Neurons; Nortriptyline; Protein Biosynthesis; Sleep; Sleep, REM; Substance Withdrawal Syndrome | 1969 |
Effect of tricyclic antidepressants on phosphodiesterase. Correlation between aggregability and thrombocyte metabolism.
Topics: Antidepressive Agents; Blood Platelets; Chlorpromazine; Dibenzothiepins; Imipramine; Nortriptyline; Phosphoric Diester Hydrolases; Platelet Adhesiveness; Serotonin | 1973 |
Effect of drugs on the activity of thrombocytes 3,5-cyclic AMP phosphodiesterase.
Topics: 1-Propanol; Adenosine Diphosphate; Adenosine Monophosphate; Aminophylline; Blood Platelets; Caffeine; Chlorpromazine; Cyclic AMP; Desipramine; Dibenzothiepins; Epinephrine; Imipramine; Nortriptyline; Phosphoric Diester Hydrolases; Piperazines; Platelet Adhesiveness | 1974 |
Lipid phase transitions and drug interactions.
Topics: Amitriptyline; Binding Sites; Calorimetry; Desipramine; Electron Spin Resonance Spectroscopy; Imipramine; Kinetics; Magnetic Resonance Spectroscopy; Membranes, Artificial; Models, Biological; Molecular Conformation; Morphinans; Morphine; Nortriptyline; Palmitic Acids; Phosphatidylcholines; Structure-Activity Relationship; Temperature; Thermodynamics | 1974 |
The effect of tricyclic antidepressive drugs on adrenaline and adenosine diphosphate induced platelet aggregation.
Topics: Adenine Nucleotides; Amitriptyline; Antidepressive Agents; Blood Platelets; Epinephrine; Imipramine; Nortriptyline | 1966 |
The intracerebral effects of noradrenaline and its modification by drugs in the mouse.
Topics: Amitriptyline; Animals; Antidepressive Agents; Ataxia; Atropine; Body Temperature; Brain; Central Nervous System; Chlordiazepoxide; Chlorpheniramine; Chlorpromazine; Diazepam; Drug Antagonism; Haloperidol; Histamine H1 Antagonists; Imipramine; Male; Mice; Norepinephrine; Nortriptyline; Pentobarbital; Phenytoin; Piperazines; Trihexyphenidyl | 1966 |
Effect of antidepressant and adrenergic blocking drugs on hyperthermia induced by reserpine.
Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Body Temperature; Chlorisondamine; Chlorpromazine; Desipramine; Ethanolamines; Female; Fever; Hydrazines; Imipramine; Monoamine Oxidase Inhibitors; Norepinephrine; Nortriptyline; Phenoxybenzamine; Phentolamine; Propranolol; Rats; Reserpine; Sympatholytics; Tetrabenazine | 1967 |
Evidence for a cholinergic mechanism in brain involved in the tetrabenazine reversal by thymoleptic drugs.
Topics: Animals; Antidepressive Agents; Brain; Desipramine; Imipramine; Male; Motor Activity; Nortriptyline; Parasympathetic Nervous System; Rats; Reserpine; Tetrabenazine | 1969 |
[Aggressiveness of the rat following combined treatment with monomaime oxidase inhibitors and other psychotropic drugs, especially thymoleptics].
Topics: Aggression; Alkaloids; Amitriptyline; Amphetamine; Animals; Anthracenes; Body Temperature; Central Nervous System; Desipramine; Dibenzazepines; Dihydroxyphenylalanine; Humans; Hydrazines; Imipramine; Indoles; Iproniazid; Isocarboxazid; Male; Nortriptyline; Opipramol; Pargyline; Phenelzine; Rats; Stimulation, Chemical; Tranylcypromine | 1969 |
Effect of antidepressant drugs on accumulation and disappearance of monoamines formed in vivo from labelled precursors in mouse brain.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Carbon Isotopes; Desipramine; Dopamine; Imipramine; Male; Mice; Norepinephrine; Nortriptyline; Serotonin; Tritium; Tryptophan; Tyrosine | 1970 |
Modification by a tricyclic series of compounds of the noradrenaline effect on the cat nictitating membrane.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cats; Desipramine; Dibenzazepines; Drug Synergism; Imipramine; Nictitating Membrane; Norepinephrine; Nortriptyline | 1971 |
Behavioural effects od d-amphetamine alone and in combination with antidepressants, antihistamines or other psychotropic drugs in young chicks.
Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Chickens; Chlorpheniramine; Cocaine; Desipramine; Dextroamphetamine; Diphenhydramine; Drug Antagonism; Drug Interactions; Histamine H1 Antagonists; Imipramine; Male; Nortriptyline; Promethazine | 1972 |
Effect of dimethyl and monomethyl tricyclic antidepressants on central 5-hydroxytryptamine processes in the frog.
Topics: Amitriptyline; Animals; Antidepressive Agents; Anura; Brain; Desipramine; Dibenzazepines; Imipramine; Male; Muscle Contraction; Nortriptyline; Rana temporaria; Serotonin | 1971 |
Poisoning as a complication of enuresis.
Topics: Amitriptyline; Antidepressive Agents; Child, Preschool; Enuresis; Humans; Imipramine; Ipecac; Nortriptyline; Seizures; Tachycardia | 1972 |
[Tricyclic anti-depressant drugs and dopamine sensitive adenylcyclase from rat caudate nuclei].
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amitriptyline; Animals; Antidepressive Agents; Basal Metabolism; Caudate Nucleus; Chlorpromazine; Desipramine; Dopamine; Imipramine; Nortriptyline; Rats; Stimulation, Chemical | 1974 |
Confusional states in elderly mental patients treated with antidepressants.
Topics: Aged; Amitriptyline; Cognition Disorders; Confusion; Depression; Drug Therapy, Combination; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Tranquilizing Agents | 1974 |
Combined thyroid (triiodothyronine)-tricyclic antidepressant treatment in depressive states.
Topics: Adjustment Disorders; Adult; Amitriptyline; Antidepressive Agents; Anxiety; Bipolar Disorder; Blood Pressure; Depression; Desipramine; Drug Therapy, Combination; Female; Humans; Imipramine; Male; Middle Aged; Motor Activity; Nortriptyline; Pulse; Time Factors; Triiodothyronine; Verbal Behavior | 1974 |
Comparison of the effects of tetracyclic and tricyclic antidepressants on the serotonin uptake by human thrombocytes in vitro.
Topics: Antidepressive Agents; Blood Platelets; Desipramine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Serotonin | 1974 |
Structure-activity relations for the inhibition of 5-hydroxytryptamine uptake by tricyclic antidepressants into synaptosomes from serotoninergic neurones in rat brain homogenates.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain Chemistry; Chlorpromazine; Hypothalamus; Imipramine; In Vitro Techniques; Iprindole; Methylation; Neurons; Nortriptyline; Promazine; Rats; Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Synaptosomes | 1974 |
Pharmacokinetic interaction between neuroleptics and tricyclic antidepressants in the rat.
Topics: Animals; Brain; Carbon Radioisotopes; Chlorpromazine; Chromatography, Thin Layer; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Erythrocytes; Feces; Glucuronates; Heart; Imipramine; Injections, Intraperitoneal; Male; Nortriptyline; Perphenazine; Rats | 1974 |
[Differentiation of secondary and tertiary tricyclic antidepressants in frogs].
Topics: Amitriptyline; Animals; Antidepressive Agents; Anura; Imipramine; Male; Nortriptyline; Phenelzine; Rana temporaria; Reserpine | 1972 |
Incorporation of imipramine into isolated rat peritoneal mast cells in vitro.
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Binding Sites; Calcium; Cell Membrane Permeability; Chlorpromazine; Cocaine; Depression, Chemical; Desipramine; Dibenzazepines; Female; Guanethidine; Hydrogen-Ion Concentration; Imipramine; Leukocytes; Male; Mast Cells; Nortriptyline; Rats; Receptors, Drug; Reserpine; Serotonin; Temperature | 1974 |
Mechanisms of catecholamine inactivation by the endocrine pancreas.
Topics: Animals; Catechol O-Methyltransferase Inhibitors; Catecholamines; Cells, Cultured; Cocaine; Cricetinae; Culture Media; Dopamine; Drug Synergism; Imipramine; Insulin; Insulin Secretion; Islets of Langerhans; Levodopa; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nortriptyline; Pargyline; Rabbits; Rats; Species Specificity; Stimulation, Chemical; Tranylcypromine | 1974 |
[Pharmacokinetic interaction between neuroleptics and antidepressive agents: organ reactions and models of metabolism].
Topics: Animals; Carbon Isotopes; Drug Interactions; Imipramine; Nortriptyline; Perphenazine; Rats | 1972 |
Functional group contribution in ion-pair extraction of tricyclic amines.
Topics: Amitriptyline; Bromides; Chemical Phenomena; Chemistry; Chlorates; Chlorides; Desipramine; Imipramine; Iodides; Ions; Mathematics; Naphthalenes; Nitrates; Nortriptyline; Spectrophotometry, Ultraviolet; Tosyl Compounds | 1972 |
Proceedings: Effect of tricyclic antidepressants on drug metabolism.
Topics: Adult; Amitriptyline; Animals; Antidepressive Agents; Antipyrine; Desipramine; Dibenzazepines; Female; Half-Life; Hexobarbital; Humans; Imipramine; Liver; Male; Nortriptyline; Rats | 1972 |
Relationship between substances strengthening of the thrombocyte cell membrane on the aggregation of thrombocytes and on the uptake and release of serotonin.
Topics: Adenosine Diphosphate; Amitriptyline; Benzothiepins; Blood Platelets; Cell Membrane; Cell Membrane Permeability; Chlorpromazine; Colorimetry; Desipramine; Epinephrine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Phentolamine; Piperazines; Platelet Adhesiveness; Propranolol; Receptors, Adrenergic; Serotonin; Serotonin Antagonists; Spectrometry, Fluorescence; Tranquilizing Agents | 1972 |
Binding of cyproheptadine-(N-methyl- 14 C) by human blood platelets: inhibition by phenothiazines and tricyclic antidepressants.
Topics: Amitriptyline; Blood Platelets; Carbon Isotopes; Centrifugation; Chlorpromazine; Cyproheptadine; Desipramine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Phenothiazines; Platelet Adhesiveness; Promethazine | 1973 |
Studies on the disposition of amitriptyline and other tricyclic antidepressant drugs in man as it relates to the management of the overdosed patient.
Topics: Adult; Amitriptyline; Antidepressive Agents; Charcoal; Chromatography, Gas; Desipramine; Female; Gastric Juice; Humans; Imipramine; Male; Mass Spectrometry; Nortriptyline; Poisoning | 1973 |
Permeability changes in the blood-brain barrier induced by nortriptyline and chlorpromazine.
Topics: Amitriptyline; Animals; Autoradiography; Blood-Brain Barrier; Brain; Capillaries; Carbon Radioisotopes; Cell Membrane Permeability; Cerebral Cortex; Chlorpromazine; Desipramine; Diphenhydramine; Dopamine; Imipramine; In Vitro Techniques; Inulin; Male; Mannitol; Molecular Weight; Nortriptyline; Rats; Tritium | 1973 |
The use of sodium bicarbonate in the treatment of tricyclic antidepressant-induced arrhythmias.
Topics: Acid-Base Equilibrium; Acidosis; Amitriptyline; Animals; Antidepressive Agents; Arrhythmias, Cardiac; Bicarbonates; Blood Proteins; Carbon Dioxide; Child, Preschool; Dibenzazepines; Dogs; Female; Humans; Hydrogen-Ion Concentration; Imipramine; Infant; Male; Nortriptyline; Protein Binding; Respiration, Artificial | 1973 |
[Evaluation of central antireserpine effect by the use of light blink reflex (author's transl)].
Topics: Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Chlorpromazine; Chlorprothixene; Desipramine; Dibenzazepines; Dibenzocycloheptenes; Diethylamines; Dimethylamines; Ethylenediamines; Glycolates; Imipramine; Light; Nortriptyline; Propylamines; Rabbits; Reflex; Reserpine | 1973 |
Stimulation of drug metabolism in man by tricyclic antidepressants.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Amitriptyline; Amobarbital; Analysis of Variance; Antidepressive Agents; Antipyrine; Desipramine; Dibenzazepines; Female; Half-Life; Humans; Hydrocortisone; Hydroxycorticosteroids; Imipramine; Male; Nortriptyline; Stimulation, Chemical; Time Factors | 1973 |
Qualitative and quantitative studies on the disposition of amitriptyline and other tricyclic antidepressant drugs in man as it relates to the management of the overdosed patient.
Topics: Absorption; Adult; Aged; Amitriptyline; Antidepressive Agents; Bile; Body Fluids; Charcoal; Chromatography, Gas; Female; Gastric Juice; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Suicide | 1973 |
Effects of antidepressant agents on open field behaviour in rats.
Topics: Animals; Behavior, Animal; Desipramine; Humans; Imipramine; Male; Nortriptyline; Pargyline; Rats; Stereotyped Behavior; Time Factors; Tranylcypromine | 1973 |
Comparison of tricyclic antidepressants in rabbits: antinociception and potentiation of the noradrenaline pressor responses.
Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Aorta; Blood Pressure; Chlorpromazine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Doxepin; Drug Synergism; Imipramine; In Vitro Techniques; Iprindole; Lithium; Morphine; Norepinephrine; Nortriptyline; Opipramol; Rabbits; Succinimides; Time Factors | 1974 |
Differential diagnosis and treatment of depression in the elderly.
Topics: Adjustment Disorders; Aged; Antidepressive Agents; Circadian Rhythm; Dementia; Depression; Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Ethanol; Humans; Imipramine; Iprindole; Middle Aged; Monoamine Oxidase Inhibitors; Nortriptyline; Orphenadrine; Physiognomy; Piperazines; Thioxanthenes | 1974 |
Drug interaction: inhibitory effect of neuroleptics on metabolism of tricyclic antidepressants in man.
Topics: Adult; Carbon Isotopes; Chlorpromazine; Drug Interactions; Ethanol; Female; Haloperidol; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Perphenazine; Piperazines; Tranquilizing Agents | 1972 |
Fluorimetric determinations by ion pair extraction. 3. Extraction constants of ion pairs between anthracene-2-sulphonate and mono- and divalent amines.
Topics: Amines; Amitriptyline; Anthracenes; Desipramine; Dibenzazepines; Emetine; Hydrocarbons, Halogenated; Imipramine; Ions; Nortriptyline; Prenylamine; Spectrometry, Fluorescence; Sulfonic Acids | 1972 |
[Neuropsychiatric aspects of male sterility].
Topics: Amitriptyline; Depression; Dibenzazepines; Frustration; Humans; Imipramine; Infertility, Male; Male; Monoamine Oxidase Inhibitors; Neurotic Disorders; Nortriptyline; Personality Disorders | 1972 |
Toxic interactions of d-amphetamine and tricyclic antidepressants in mice.
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Dextroamphetamine; Drug Antagonism; Drug Interactions; Drug Synergism; Imipramine; Injections, Intraperitoneal; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Nortriptyline; Promazine; Time Factors | 1972 |
Interaction between digoxin and tricyclic antidepressants in the rat.
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Heart; Heart Arrest; Imipramine; Male; Nortriptyline; Rats; Reserpine; Stress, Physiological | 1972 |
Overdosage of tricyclic antidepressants. A report of two deaths and a prospective study of 24 patients.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents; Arrhythmias, Cardiac; Bundle-Branch Block; Electrocardiography; Female; Fever of Unknown Origin; Heart Block; Heart Conduction System; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Prospective Studies; Psychoses, Substance-Induced; Seizures | 1972 |
The use of psychopharmacological drugs in the aged.
Topics: Affective Symptoms; Aged; Antidepressive Agents; Anxiety; Barbiturates; Butyrophenones; Dementia; Desipramine; Dextroamphetamine; Diazepam; Humans; Imipramine; Isocarboxazid; Mental Disorders; Monoamine Oxidase Inhibitors; Nortriptyline; Phenelzine; Phenothiazines; Phytotherapy; Piperazines; Plants, Medicinal; Rauwolfia; Thiothixene; Tranquilizing Agents; Tranylcypromine; Xanthenes | 1971 |
Interaction of imipramine, desmethylimipramine, nortriptyline and 1-naphthol with microsomal preparations.
Topics: Animals; Desipramine; Drug Interactions; Hydroxylation; Imipramine; Microsomes, Liver; Naphthalenes; Naphthols; Nortriptyline; Rats | 1971 |
[Drug interactions: blocking effect of neuroleptics on the metabolism of tricyclic antidepressive agents].
Topics: Carbon Isotopes; Drug Interactions; Humans; Imipramine; Nortriptyline; Perphenazine; Tranquilizing Agents | 1971 |
Metabolism of propranolol by rat liver microsomes and its inhibition by phenothiazine and tricyclic antidepressant drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Desipramine; Imipramine; Kinetics; Liver; Male; Metabolism; Microsomes, Liver; NAD; NADP; Nitrogen; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Propranolol; Rats; Subcellular Fractions; Trifluoperazine; Triflupromazine | 1971 |
[Changes in tonus of the bladder and its sphincter under thymoleptic treatment. Cystomanometric measurements in man].
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Carbachol; Desipramine; Dibenzazepines; Enuresis; Humans; Imipramine; Manometry; Middle Aged; Muscle Tonus; Nortriptyline; Pressure; Urinary Bladder; Water-Electrolyte Balance | 1971 |
Pharmacotherapy in the premenstrual tension.
Topics: Adolescent; Adult; Bipolar Disorder; Chlorpromazine; Depression; Female; Humans; Imipramine; Neurotic Disorders; Nortriptyline; Premenstrual Syndrome; Social Adjustment | 1971 |
Effect of some drugs on the uptake of monoamines and their precursors in the mouse Paneth cells.
Topics: 5-Hydroxytryptophan; Amines; Amitriptyline; Amphetamine; Animals; Binding Sites; Catecholamines; Chlorpromazine; Cocaine; Colon; Cytoplasmic Granules; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Duodenum; Female; Guanethidine; Ileum; Imipramine; Jejunum; Male; Methyltyrosines; Mice; Microscopy, Fluorescence; Nortriptyline; Pargyline; Peptide Biosynthesis; Promazine; Reserpine; Serotonin; Tyrosine | 1971 |
Plasma protein binding of tricyclic anti-depressants in man.
Topics: Amitriptyline; Antidepressive Agents; Blood Proteins; Carbon Isotopes; Desipramine; Humans; Imipramine; Nortriptyline; Phenytoin; Protein Binding; Temperature; Tritium | 1969 |
Studies of the influence of some psychotropic substances on the grooming behaviour of white mice.
Topics: Amitriptyline; Animals; Aspirin; Charcoal; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Female; Grooming; Haloperidol; Imipramine; Iproniazid; Metronidazole; Mice; Nortriptyline; Psychopharmacology | 1969 |
Inhibition of the uptake of tritiated 5-hydroxytryptamine in brain tissue.
Topics: Amitriptyline; Animals; Antidepressive Agents; Antimetabolites; Brain; Cocaine; Desipramine; Imipramine; In Vitro Techniques; Mice; Nortriptyline; Reserpine; Serotonin; Tritium; Tryptamines | 1969 |
Effects of tricyclic antidepressants on the uptake and mabolism of intracisternally administered norepinephrine-H3 in rat brain.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Brain Chemistry; Cell Membrane; Cerebral Ventricles; Desipramine; Imipramine; Injections; Injections, Intraperitoneal; Male; Mitochondria; Norepinephrine; Normetanephrine; Nortriptyline; Rats; Tritium | 1969 |
Use of antidepressant drugs during the first trimester.
Topics: Amitriptyline; Desipramine; Embryo, Mammalian; Female; Gestational Age; Humans; Imipramine; Nortriptyline; Pregnancy | 1969 |
[A possible mechanism of disaggregation of ADP-induced aggregates by imipramin and structurally related compouds].
Topics: Adenine Nucleotides; Amitriptyline; Blood Platelets; Chlorpromazine; Desipramine; Diphenhydramine; Humans; Imipramine; Nortriptyline; Optical Rotatory Dispersion; Platelet Adhesiveness; Promazine; Promethazine | 1969 |
[Cardiodepressive and local anesthetic effect of thymoleptics. Comparative studies with imipramine, desipramine, amitriptyline, nortriptyline and melitracene].
Topics: Amitriptyline; Anesthetics, Local; Animals; Anthracenes; Cornea; Depression, Chemical; Desipramine; Drug Synergism; Guinea Pigs; Heart Rate; Imipramine; In Vitro Techniques; Norepinephrine; Nortriptyline; Rabbits; Time Factors; Tyramine | 1969 |
[Thymoleptics and lipolysis].
Topics: Adipose Tissue; Amitriptyline; Animals; Antidepressive Agents; Cocaine; Depression, Chemical; Desipramine; Dibenzazepines; Fatty Acids, Nonesterified; Imipramine; In Vitro Techniques; Lipid Metabolism; Male; Norepinephrine; Nortriptyline; Photometry; Rats; Stimulation, Chemical; Tranquilizing Agents | 1969 |
Kinetic and thermodynamic considerations regarding the inhibition by tricyclic antidepressants of the uptake of tritiated norepinephrine by the adrenergic nerves in rabbit aortic strips.
Topics: Animals; Antidepressive Agents; Aorta; Desipramine; Energy Transfer; Female; Imipramine; Kinetics; Male; Muscle Contraction; Muscles; Neurons; Norepinephrine; Nortriptyline; Protein Binding; Rabbits; Sympathetic Nervous System; Tritium; Tyramine | 1970 |
Persistent extrapyramidal oral dyskinesias following treatment with thymoleptics.
Topics: Aged; Amitriptyline; Antidepressive Agents; Depressive Disorder, Major; Facial Muscles; Female; Humans; Imipramine; Lip; Middle Aged; Movement Disorders; Nortriptyline; Tongue | 1970 |
[Current problems of endogenous depression].
Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Convulsive Therapy; Depression; Desipramine; Fluphenazine; Humans; Imipramine; Methotrimeprazine; Nortriptyline; Perphenazine; Thioridazine | 1970 |
[Clinical antidepressant drug therapy].
Topics: Amitriptyline; Antidepressive Agents; Depression; Desipramine; Dibenzazepines; Humans; Imipramine; Nortriptyline; Prognosis | 1970 |
Aggressive behaviour in chicks induced by tricyclic antidepressants.
Topics: Aggression; Animals; Behavior, Animal; Chickens; Desipramine; Dibenzazepines; Dibenzocycloheptenes; Female; Humans; Imipramine; Male; Motor Activity; Nortriptyline | 1970 |
Noveril (dibenzepin)--another new antidepressive.
Topics: Amitriptyline; Antidepressive Agents; Depression; Dibenzazepines; Humans; Imipramine; Nortriptyline | 1970 |
Antianxiety and anti-depressant drugs.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Depression; Desipramine; Dibenzoxepins; Humans; Imipramine; Nortriptyline; Tranquilizing Agents | 1970 |
Observation of the grooming behaviour of reserpinized white mice as a method for investigating reserpine antagonism and synergism.
Topics: Administration, Oral; Animals; Antidepressive Agents; Blepharoptosis; Charcoal; Desipramine; Dextroamphetamine; Dibenzazepines; Drug Synergism; Female; Grooming; Imipramine; Injections, Intravenous; Iproniazid; Methods; Mice; Nortriptyline; Propylamines; Reserpine | 1970 |
[Pharmacological studies of a new antidepressant nortriptyline (Noritren)].
Topics: Amitriptyline; Animals; Behavior, Animal; Body Temperature; Brain Chemistry; Cats; Chlorpromazine; Conditioning, Classical; Electroencephalography; Haloperidol; Imipramine; Mice; Norepinephrine; Nortriptyline; Perphenazine; Rats; Reserpine; Serotonin; Sleep | 1970 |
[Complications caused by anonymous preclinical medication].
Topics: Amitriptyline; Antidepressive Agents; Barbiturates; Bromides; Cannabis; Chlordiazepoxide; Delirium; Depression; Female; Hallucinogens; Haloperidol; Humans; Imipramine; Lysergic Acid Diethylamide; Male; Nortriptyline; Phenacetin; Self Medication; Substance-Related Disorders | 1970 |
[Animal experiments to study the cardiotoxic effect of thymoleptics].
Topics: Amitriptyline; Animals; Blood Pressure; Cats; Desipramine; Drug Synergism; Epinephrine; Heart; Heart Failure; Humans; Imipramine; Nortriptyline; Tranquilizing Agents | 1971 |
[Therapy of polyneuritides].
Topics: Butyrophenones; Chlorpromazine; Glucocorticoids; Humans; Hypoxia; Imipramine; Methotrimeprazine; Nortriptyline; Pain; Polyneuropathies; Tranquilizing Agents; Vitamin B Complex | 1971 |
Tricyclic antidepressants and monoamine oxidase inhibitors.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amitriptyline; Animals; Depression; Desipramine; Drug Synergism; Female; Fever; Humans; Hypertension; Hypotension; Imipramine; Isocarboxazid; Male; Middle Aged; Monoamine Oxidase Inhibitors; Nortriptyline; Phenelzine; Seizures | 1971 |
Comparative study of imipramine, amitriptyline and their desmethyl analogues in the hypothyroid rat.
Topics: Amitriptyline; Animals; Blepharoptosis; Desipramine; Exploratory Behavior; Female; Hypothyroidism; Imipramine; Motor Activity; Nortriptyline; Posture; Propylthiouracil; Psychopharmacology; Rats; Sympathomimetics; Tetrabenazine | 1967 |
Mechanism of inhibition of experimental inflammation by antidepressant drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents; Carrageenan; Catecholamines; Desipramine; Dextrans; Drug Synergism; Edema; Female; Formaldehyde; Imipramine; Nortriptyline; Rats | 1967 |
[On the management of pain using antidepressive agents].
Topics: Amitriptyline; Antidepressive Agents; Desipramine; Humans; Imipramine; Nortriptyline; Pain | 1967 |
[Nortriptyline poisoning].
Topics: Adult; Amitriptyline; Desipramine; Female; Humans; Imipramine; Nortriptyline | 1967 |
Tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Desipramine; Dibenzazepines; Enuresis; Humans; Imipramine; Nortriptyline; Opipramol | 1968 |
Toxicity of depressant and antidepressant drugs in hyperthyroid mice.
Topics: Animals; Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Female; Hyperthyroidism; Imipramine; Meprobamate; Mice; Nortriptyline; Oxygen Consumption; Perphenazine; Phenothiazines; Reserpine; Sympathomimetics; Tranquilizing Agents | 1968 |
Studies of the influence of some psychotropic substances on the grooming behaviour of white mice.
Topics: Amitriptyline; Animals; Aspirin; Charcoal; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Grooming; Haloperidol; Imipramine; Iproniazid; Metronidazole; Mice; Nortriptyline; Sodium Chloride; Solvents; Tranquilizing Agents | 1968 |
Potentiation of 5-hydroxytryptamine release from platelets by desmethylation of chlorpromazine and related agents.
Topics: Amitriptyline; Animals; Blood Platelets; Chlorpromazine; Drug Synergism; Imipramine; Methylation; Nortriptyline; Rabbits; Serotonin | 1968 |
[On the analgesic affect of thymoleptics].
Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Codeine; Desipramine; Dibenzazepines; Humans; Imipramine; Male; Mice; Nortriptyline; Phosphates; Quinones; Tranquilizing Agents | 1968 |
[Investigation of gastric ulcer inhibiting and secreto-inhibitory actions of thymoleptics in rats].
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Gastric Juice; Imipramine; Nortriptyline; Rats; Stomach Ulcer | 1968 |
The effect of antidepressants and "tranquilizers" on the response of mice to ethanol.
Topics: Accidents, Traffic; Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Coma; Desipramine; Diazepam; Dibenzazepines; Drug Synergism; Ethanol; Humans; Imipramine; Methylphenidate; Mice; Nortriptyline; Phenelzine; Phenobarbital; Reflex; Substance-Related Disorders; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1968 |
The interactions of noradnamine and imipramine-like antidepressant drugs.
Topics: Animals; Antidepressive Agents; Brain Chemistry; Cerebral Ventricles; Dibenzocycloheptenes; Hypothermia; Imipramine; Male; Mice; Norepinephrine; Nortriptyline; Seizures; Serotonin; Sympathomimetics | 1969 |
Sensitivity and specificity of positive reinforcing areas to neurosedatives, antidepressants and stimulants.
Topics: Animals; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Electric Stimulation; Electrodes; Hypothalamus; Imipramine; Male; Mesencephalon; Nortriptyline; Rats; Self Stimulation; Spinal Cord | 1969 |
Masked depression and the use of antidepressants in general practice.
Topics: Adult; Age Factors; Amitriptyline; Antidepressive Agents; Depression; Family Practice; Female; Humans; Imipramine; Iproniazid; Male; Middle Aged; Nortriptyline; Phenelzine; Retrospective Studies; Sex Factors; Tranylcypromine | 1969 |
Molecular features affecting the potency of tricyclic antidepressants and structurally related compounds as inhibitors of the uptake of tritiated norepinephrine by rabbit aortic strips.
Topics: Amitriptyline; Animals; Antidepressive Agents; Aorta; Benzazepines; Carbazoles; Chemical Phenomena; Chemistry; Dibenzocycloheptenes; Imipramine; In Vitro Techniques; Kinetics; Models, Chemical; Norepinephrine; Nortriptyline; Rabbits; Stereoisomerism | 1969 |
Nocturnal enuresis in children.
Topics: Child; Child, Preschool; Dextroamphetamine; Enuresis; Humans; Imipramine; Nortriptyline; Parasympatholytics; Psychotherapy; Sympathomimetics | 1969 |
Cardiac abnormalities in poisoning with tricyclic antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents; Arrhythmias, Cardiac; Desipramine; Electrocardiography; Female; Heart; Humans; Imipramine; Nortriptyline | 1969 |
[Research on the mechanisms of the protective activity against gastric ulcer of psychoactive drugs: effects of nortriptyline, imipramine and chlorpromazine on gastric secretion].
Topics: Animals; Atropine; Chlorpromazine; Gastric Juice; Imipramine; Nortriptyline; Rats; Stomach Ulcer | 1965 |
Effect of electroshock and antidepressant drugs on cerebrovascular permeability to cocaine in the rat.
Topics: Amitriptyline; Animals; Antidepressive Agents; Blood-Brain Barrier; Chlorpromazine; Cocaine; Electric Stimulation; Electroshock; Female; Imipramine; Injections, Intravenous; Nortriptyline; Rats | 1966 |
Poisoning by amitriptyline, imipramine and nortriptyline.
Topics: Amitriptyline; Animals; Antidepressive Agents; Humans; Imipramine; Mice; Nortriptyline | 1966 |
[Comparative clinical experiences with Protriptyline in depressive conditions of various origins].
Topics: Amitriptyline; Antidepressive Agents; Depression; Desipramine; Dibenzazepines; Humans; Imipramine; Nortriptyline; Opipramol | 1966 |
[Restraining action of antidepressive agents of the imipramine group on the cardiovascular centers].
Topics: Action Potentials; Amitriptyline; Amygdala; Animals; Antidepressive Agents; Blood Pressure; Carotid Arteries; Cats; Desipramine; Hypertension; Hypothalamus; Imipramine; Medulla Oblongata; Mesencephalon; Nictitating Membrane; Nortriptyline; Rats; Sciatic Nerve; Splanchnic Nerves | 1967 |
Plasma levels of monomethylated tricyclic antidepressants during treatment with imipramine-like compounds.
Topics: Adult; Amitriptyline; Desipramine; Female; Humans; Imipramine; Male; Nortriptyline | 1967 |
[Clinical studies of a new antidepressive agent, nortriptyline].
Topics: Adolescent; Adult; Aged; Amitriptyline; Depression; Desipramine; Humans; Imipramine; Middle Aged; Neurotic Disorders; Nortriptyline | 1967 |
[Place of nortriptyline in the group of antidepressants; clinical and electroencephalographic considerations].
Topics: Amitriptyline; Depression; Humans; Imipramine; Nortriptyline | 1967 |
Effect of neuroleptics and tricyclic antidepressants upon d-amphetamine discrimination.
Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dextroamphetamine; Discrimination, Psychological; Dose-Response Relationship, Drug; Fluphenazine; Haloperidol; Imipramine; Male; Nortriptyline; Promethazine; Rats; Sodium Chloride; Thioridazine; Trifluoperazine | 1980 |
The contribution of pharmacokinetics to the best use of benzodiazepines and antidepressants.
Topics: Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Benzodiazepines; Depressive Disorder; Half-Life; Humans; Imipramine; Kinetics; Metabolic Clearance Rate; Nortriptyline | 1982 |
Therapeutic drug monitoring of psychotropic drugs in children.
Topics: Adolescent; Adult; Age Factors; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Child; Child, Preschool; Chlorpromazine; Clomipramine; Dose-Response Relationship, Drug; Half-Life; Haloperidol; Humans; Imipramine; Kinetics; Mental Disorders; Nortriptyline | 1983 |
Weight gain. A side-effect of tricyclic antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Appetite; Body Weight; Depressive Disorder; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Retrospective Studies | 1984 |
Interactions of tricyclic antidepressants with a synaptic ion channel.
Topics: Acetylcholine; Amitriptyline; Amphibian Venoms; Animals; Antidepressive Agents, Tricyclic; Binding Sites; Desipramine; Electric Organ; Fishes; Imipramine; Ion Channels; Nortriptyline; Phencyclidine; Receptors, Nicotinic | 1981 |
Comparison of imipramine- and nortriptyline-induced orthostatic hypotension: a meaningful difference.
Topics: Humans; Hypotension, Orthostatic; Imipramine; Middle Aged; Nortriptyline; Receptors, Adrenergic, alpha | 1981 |
Effect of tricyclic antidepressant drugs on lymphocyte membrane structure.
Topics: Animals; Antidepressive Agents, Tricyclic; Cell Membrane; Cells, Cultured; Desipramine; Dose-Response Relationship, Drug; Fluorescent Dyes; Imipramine; Lymphocytes; Male; Mice; Nortriptyline; Protriptyline; Spleen; Temperature; Time Factors | 1984 |
The complex binding of tricyclic antidepressants to rat brain: the case of nortriptyline.
Topics: Animals; Autoradiography; Binding Sites; Brain; Desipramine; Imipramine; Nortriptyline; Rats | 1984 |
Blood collection tubes for tricyclic antidepressant drugs: a reevaluation.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Blood Preservation; Blood Proteins; Blood Specimen Collection; Desipramine; Humans; Imipramine; Nortriptyline; Plasma | 1984 |
Simultaneous measurement of various antidepressants in the plasma of depressed patients by high performance liquid chromatography.
Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents; Chromatography, High Pressure Liquid; Clomipramine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline | 1984 |
3H-imipramine binding sites in brain down-regulated by chronic nortriptyline and haloperidol but not mianserin treatment.
Topics: Animals; Cerebral Cortex; Dibenzazepines; Haloperidol; Hippocampus; Imipramine; Male; Mianserin; Nortriptyline; Rats; Rats, Inbred Strains; Time Factors; Tritium | 1984 |
Liquid chromatographic separation of antidepressant drugs: I. Tricyclics.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Promazine; Protriptyline | 1983 |
Cimetidine interaction with imipramine and nortriptyline.
Topics: Adult; Biological Availability; Cimetidine; Desipramine; Drug Interactions; Humans; Imipramine; Kinetics; Male; Nortriptyline | 1984 |
Depression: diagnosis and treatment with tricyclic antidepressants.
Topics: Age Factors; Antidepressive Agents, Tricyclic; Black People; Chromatography, High Pressure Liquid; Depressive Disorder; Dexamethasone; Heart Diseases; Humans; Hypotension; Imipramine; Nortriptyline; Psychotherapy; Thyrotropin; Thyrotropin-Releasing Hormone | 1981 |
The dexamethasone suppression test in depressive illness: clinical correlates.
Topics: Depressive Disorder; Desipramine; Dexamethasone; Diagnosis, Differential; Double-Blind Method; Doxepin; Electroconvulsive Therapy; Female; Humans; Hydrocortisone; Imipramine; Male; Mianserin; Middle Aged; Nortriptyline; Phenelzine; Psychiatric Status Rating Scales; Selegiline | 1982 |
Column deactivation in analysis for underivatized tricyclic antidepressants by gas chromatography with use of a nitrogen detector.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Desipramine; Humans; Imipramine; Nitrogen; Nortriptyline | 1983 |
Complex inhibition of [3H]imipramine binding by serotonin and nontricyclic serotonin uptake blockers.
Topics: Amitriptyline; Animals; Binding, Competitive; Cerebral Cortex; Clomipramine; Desipramine; Imipramine; Male; Nortriptyline; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists | 1983 |
Pharmacologic treatment of childhood depressive disorders.
Topics: Child; Depressive Disorder; Humans; Imipramine; Nortriptyline | 1983 |
Differential effects of tricyclic antidepressants on mean arterial pressure in a hypertensive patient.
Topics: Blood Pressure; Depressive Disorder; Humans; Hypertension; Hypotension, Orthostatic; Imipramine; Male; Middle Aged; Nortriptyline; Phenelzine | 1983 |
The methylphenidate test for differentiating desipramine-responsive from nortriptyline-responsive depression.
Topics: Adolescent; Adult; Amitriptyline; Depressive Disorder; Desipramine; Emotions; Humans; Imipramine; Methylphenidate; Middle Aged; Norepinephrine; Nortriptyline | 1983 |
Plasma concentrations of tricyclic antidepressants in clinical practice.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biotransformation; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Humans; Imipramine; Nortriptyline | 1982 |
Tricyclic antidepressants and cardiac patients with pacemakers.
Topics: Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Desipramine; Female; Heart Rate; Humans; Imipramine; Male; Nortriptyline; Pacemaker, Artificial; Sick Sinus Syndrome | 1982 |
Tricyclic antidepressant plasma levels: the state of the art and clinical prospects.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biotransformation; Bipolar Disorder; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Imipramine; Nortriptyline | 1982 |
TCA-induced mania: differences between switchers and nonswitchers.
Topics: Adult; Affective Disorders, Psychotic; Age Factors; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Desipramine; Doxepin; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Protriptyline | 1982 |
Bonded-phase extraction of plasma tricyclic antidepressant drugs for gas chromatographic analysis.
Topics: Acetates; Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Desipramine; Humans; Imipramine; Methods; Nortriptyline | 1982 |
Reversible loss of nocturnal penile tumescence during depression: a preliminary report.
Topics: Aged; Depressive Disorder; Erectile Dysfunction; Humans; Imipramine; Libido; Male; Middle Aged; Nortriptyline; Sleep Stages; Sleep, REM | 1982 |
The relationship of therapeutic response to antidepressant plasma levels: an update.
Topics: Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents; Biological Availability; Depressive Disorder; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Patient Compliance; Protriptyline | 1982 |
Evidence for in vivo methylation of the secondary amino antidepressant desipramine to imipramine in humans.
Topics: Amitriptyline; Biotransformation; Depressive Disorder; Desipramine; Humans; Imipramine; Methylation; Nortriptyline | 1982 |
Simultaneous liquid chromatographic analysis of amitriptyline, nortriptyline, imipramine, desipramine, doxepin, and nordoxepin.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline | 1981 |
Liquid-chromatographic analysis for common tricyclic antidepressant drugs and their metabolites in serum or plasma with the technicon "FAST-LC" system.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Autoanalysis; Chromatography, High Pressure Liquid; Desipramine; Doxepin; Humans; Imipramine; Nortriptyline; Protriptyline | 1981 |
Reversed-phase liquid chromatography and gas chromatography/mass fragmentography compared for determination of tricyclic antidepressant drugs.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Gas Chromatography-Mass Spectrometry; Humans; Imipramine; Nortriptyline | 1981 |
Tricyclic antidepressant blood levels: eight practical questions.
Topics: Age Factors; Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Dose-Response Relationship, Drug; Humans; Imipramine; Intestinal Absorption; Nortriptyline | 1981 |
Antidepressants inhibit enkephalin binding to synaptosome-enriched fractions of rat brain.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Imipramine; Male; Nortriptyline; Rats; Rats, Inbred Strains; Synaptosomes; Viloxazine | 1981 |
Tricyclic antidepressants: a simplified approach for the routine clinical monitoring of parent drug and metabolites in plasma using HPLC.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Humans; Imipramine; Monitoring, Physiologic; Nortriptyline | 1981 |
Quantitative analysis for tricyclic antidepressant drugs in plasma or serum by gas chromatography-chemical-ionization mass spectrometry.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Desipramine; Female; Gas Chromatography-Mass Spectrometry; Humans; Imipramine; Male; Middle Aged; Nortriptyline | 1980 |
An external quality-control scheme for tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Blood Chemical Analysis; Desipramine; Humans; Imipramine; Laboratories; Nortriptyline; Quality Control; United Kingdom | 1980 |
Novel solid-phase extraction strategy for the isolation of basic drugs from whole blood. Preliminary study using commercially available extraction cartridges.
Topics: Adsorption; Animals; Blood Chemical Analysis; Cation Exchange Resins; Chromatography; Gas Chromatography-Mass Spectrometry; Imipramine; Nortriptyline; Pharmaceutical Preparations; Propranolol; Quinine; Sheep; Solubility | 1995 |
Alpha-adrenergic receptors mediate imipramine/alarm substance-induced reaction in rats.
Topics: Animals; Arousal; Brain; Citalopram; Clonidine; Dose-Response Relationship, Drug; Imipramine; Male; Norepinephrine; Nortriptyline; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-2; Receptors, GABA; Reserpine; Serotonin; Yohimbine | 1994 |
Concurrent liquid chromatographic measurement of fluoxetine, amitriptyline, imipramine, and their active metabolites norfluoxetine, nortriptyline, and desipramine in plasma.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Desipramine; Fluoxetine; Humans; Imipramine; Indicators and Reagents; Nortriptyline; Spectrophotometry, Ultraviolet | 1993 |
The study of tricyclic antidepressants in formalin-fixed human liver and formalin solutions.
Topics: Amitriptyline; Cryopreservation; Desipramine; Drug Overdose; Drug Stability; Embalming; Evaluation Studies as Topic; Forensic Medicine; Formaldehyde; Humans; Imipramine; Liver; Methylation; Nortriptyline; Poisoning; Temperature; Time Factors | 1993 |
Alterations in plasma dipeptidyl peptidase IV enzyme activity in depression and schizophrenia: effects of antidepressants and antipsychotic drugs.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Dipeptidyl Peptidase 4; Dose-Response Relationship, Drug; Female; Fluoxetine; Haloperidol; Humans; Hydrocortisone; Imipramine; Male; Middle Aged; Nortriptyline; Perphenazine; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology | 1996 |
The Pisa syndrome (pleurothotonus) during antidepressant therapy.
Topics: Amitriptyline; Antidepressive Agents; Biperiden; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline; Orientation; Postural Balance; Posture | 1997 |
Acute lung failure induced by tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Overdose; Imipramine; Lung; Maprotiline; Mianserin; Microscopy, Electron; Nortriptyline; Organ Size; Perfusion; Pulmonary Edema; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley | 1997 |
Elevated levels of erythropoietin in cerebrospinal fluid of depressed patients.
Topics: Antidepressive Agents, Tricyclic; Cerebrovascular Disorders; Depression; Erythropoietin; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline | 1998 |
Central NO is involved in the antinociceptive action of intracisternal antidepressants in freely moving rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Arginine; Desipramine; Electric Stimulation; Electromyography; Enzyme Inhibitors; Imipramine; Jaw; Locomotion; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociceptors; Nortriptyline; Rats; Rats, Sprague-Dawley; Reflex | 1998 |
Quantitative determination of tricyclic antidepressants and their metabolites in plasma by solid-phase extraction (Bond-Elut TCA) and separation by capillary gas chromatography with nitrogen-phosphorous detection.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Desipramine; Drug Monitoring; Humans; Imipramine; Linear Models; Nortriptyline; Promazine; Sensitivity and Specificity | 1998 |
Stability of tricyclic antidepressants in formalin solutions.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Drug Stability; Forensic Medicine; Formaldehyde; Imipramine; Nortriptyline; Substance Abuse Detection; Time Factors | 1998 |
Nonaqueous capillary electrophoretic separation and thermo-optical absorbance detection of five tricyclic antidepressants and metabolism of amitriptyline by Cunninghamella elegans.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Cunninghamella; Desipramine; Electrophoresis, Capillary; Imipramine; Molecular Structure; Nortriptyline | 1998 |
Amitriptyline-induced loss of tight junction integrity in a human endothelial--smooth muscle cell bi-layer model.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Coculture Techniques; Desipramine; Electric Impedance; Endothelium, Vascular; Fluorescent Antibody Technique, Indirect; Formazans; Humans; Imipramine; Muscle, Smooth, Vascular; Nortriptyline; Spectrometry, Fluorescence; Tetrazolium Salts; Tight Junctions; Umbilical Cord | 1999 |
Effect of fluoxetine on contractile activity of pregnant rat uterine rings.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Tricyclic; Dose-Response Relationship, Drug; Female; Fluoxetine; Imipramine; Isometric Contraction; Nortriptyline; Pregnancy; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Uterine Contraction; Uterus | 2000 |
Medication treatment versus cognitive behavior therapy.
Topics: Ambulatory Care; Antidepressive Agents; Cognitive Behavioral Therapy; Depressive Disorder; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Research Design; Severity of Illness Index; Treatment Outcome | 2000 |
Electrophysiologic analysis of antidepressant drug effects on the GABA(A) receptor complex based upon antagonist-induced encephalographic power spectrum changes.
Topics: Animals; Antidepressive Agents; Desipramine; Electroencephalography; Fluoxetine; Fourier Analysis; GABA Antagonists; Hippocampus; Imipramine; Male; Nortriptyline; Pentylenetetrazole; Rats; Rats, Wistar; Trazodone | 2000 |
Sample preparation with fiber-in-tube solid-phase microextraction for capillary electrophoretic separation of tricyclic antidepressant drugs in human urine.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Imipramine; Nortriptyline; Specimen Handling | 2001 |
Inhibition of acetylcholinesterase from Electrophorus electricus (L.) by tricyclic antidepressants.
Topics: Acetylcholinesterase; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cholinesterase Inhibitors; Coloring Agents; Electrophorus; Imipramine; Molecular Structure; Nortriptyline; Propidium; Protein Binding; Spectrometry, Fluorescence | 2002 |
[TREATMENT OF ENDOGENOUS DEPRESSIONS WITH ANTIDEPRESSIVE AGENTS AND ELECTROSHOCK AND TREATMENT BEFORE 1937].
Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Electroconvulsive Therapy; Electroshock; Humans; Imipramine; Mental Disorders; Monoamine Oxidase Inhibitors; Nortriptyline; Psychotherapy | 1964 |
THE DIAGNOSIS AND MANAGEMENT OF DEPRESSION.
Topics: Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Classification; Depression; Depressive Disorder; Desipramine; Diagnosis; Drug Therapy; Humans; Imipramine; Monoamine Oxidase Inhibitors; Nortriptyline; Tyramine | 1965 |
[MEDICAL ANTIDEPRESSIVE TREATMENT. NORTRIPTYLINE EVALUATED IN COMPARISON WITH AMITRIPTYLINE AND IMIPRAMINE].
Topics: Adolescent; Amitriptyline; Antidepressive Agents; Depression; Depressive Disorder; Geriatrics; Imipramine; Nortriptyline; Toxicology | 1965 |
ATTEMPT TO DIFFERENTIATE THYMOLEPTICS AND NEUROLEPTICS BY MEANS OF THEIR INFLUENCE ON THE EFFECTS OF RESERPINE.
Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; Body Temperature; Chlorpromazine; Chlorprothixene; Desipramine; Eyelids; Imipramine; Mice; Nortriptyline; Peptic Ulcer; Pharmacology; Rats; Research; Reserpine; Toxicology; Tranquilizing Agents | 1964 |
PHARMACOLOGICAL PROPERTIES OF THE DESMETHYL DERIVATIVES OF SOME ANTIDEPRESSANTS OF IMIPRAMINE TYPE.
Topics: Amitriptyline; Animals; Antidepressive Agents; Caffeine; Desipramine; Hypothermia; Hypothermia, Induced; Imipramine; Injections, Intraperitoneal; Mice; Nortriptyline; Pentylenetetrazole; Peptic Ulcer; Rats; Research; Reserpine; Selective Serotonin Reuptake Inhibitors; Serotonin; Strychnine; Toxicology; Tranquilizing Agents | 1965 |
Excess fatality from desipramine and dosage recommendations.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Databases, Factual; Desipramine; Drug Overdose; Humans; Imipramine; Nortriptyline; United Kingdom; United States | 2004 |
Excess fatality from desipramine in children and adolescents.
Topics: Adolescent; Amitriptyline; Child; Desipramine; Doxepin; Humans; Imipramine; Incidence; Mortality; Nortriptyline; Prevalence; Substance-Related Disorders | 2006 |
Optimization of solid-phase microextraction procedures for the determination of tricyclic antidepressants and anticonvulsants in plasma samples by liquid chromatography.
Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Chromatography, Liquid; Desipramine; Epoxy Compounds; Humans; Hydrogen-Ion Concentration; Imipramine; Lamotrigine; Nortriptyline; Phenobarbital; Phenylethylmalonamide; Polyurethanes; Primidone; Reproducibility of Results; Sensitivity and Specificity; Silanes; Time Factors; Triazines | 2006 |
Comparative metabolic capabilities and inhibitory profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17.
Topics: Atomoxetine Hydrochloride; Cocaine; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Debrisoquin; Dextromethorphan; Enzyme Inhibitors; Ethanolamines; Fluoxetine; Humans; Hydroxylation; Imipramine; Kinetics; Microsomes; Molecular Structure; Nortriptyline; Polymorphism, Single Nucleotide; Propylamines; Quinidine; Recombinant Proteins; Thioridazine; Tramadol | 2007 |
Analysis of tricyclic antidepressant drugs in plasma by means of solid-phase microextraction-liquid chromatography-mass spectrometry.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Blood Chemical Analysis; Chromatography, Liquid; Clomipramine; Desipramine; Humans; Imipramine; Nortriptyline; Solid Phase Microextraction; Spectrometry, Mass, Electrospray Ionization | 2007 |
In vitro biotransformation of amitriptyline and imipramine with rat hepatic S9 fraction: evaluation of the toxicity with Spirotox and Thamnotoxkit F Tests.
Topics: Amitriptyline; Animals; Anostraca; Biotransformation; Ciliophora; Desipramine; Imipramine; Lethal Dose 50; Liver; Male; Nortriptyline; Rats; Rats, Sprague-Dawley; Toxicity Tests; Water Pollutants, Chemical | 2008 |
IFN-gamma reduction by tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cyclohexanols; Cytokines; Depressive Disorder; Desipramine; Desvenlafaxine Succinate; Female; Humans; Imipramine; In Vitro Techniques; Interferon-gamma; Male; Nortriptyline; Venlafaxine Hydrochloride | 2010 |
Pharmacophore modeling for hERG channel facilitation.
Topics: Animals; Atenolol; Chlorpheniramine; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoxetine; Haloperidol; Humans; Hydrophobic and Hydrophilic Interactions; Imipramine; Metoprolol; Nortriptyline; Potassium Channel Blockers; Promethazine; Propranolol; Quantitative Structure-Activity Relationship; Sotalol; Terfenadine; Verapamil; Xenopus laevis | 2012 |
Tricyclic antidepressants: is your patient taking them? Observations on adherence and unreported use using prescriber-reported medication lists and urine drug testing.
Topics: Adolescent; Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Drug Interactions; Female; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Pain; Retrospective Studies; Sex Factors; Young Adult | 2014 |
A simple dried blood spot method for therapeutic drug monitoring of the tricyclic antidepressants amitriptyline, nortriptyline, imipramine, clomipramine, and their active metabolites using LC-MS/MS.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biotransformation; Calibration; Chromatography, Liquid; Clomipramine; Depressive Disorder, Major; Dried Blood Spot Testing; Drug Monitoring; Hematocrit; Humans; Imipramine; Limit of Detection; Nortriptyline; Reproducibility of Results; Tandem Mass Spectrometry | 2015 |
Quantification of Tricyclic Antidepressants in Serum Using Liquid Chromatography Electrospray Tandem Mass Spectrometry (HPLC-ESI-MS/MS).
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Desipramine; Humans; Imipramine; Nortriptyline; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2016 |
Tricyclic antidepressants inhibit Candida albicans growth and biofilm formation.
Topics: Amphotericin B; Antidepressive Agents, Tricyclic; Antifungal Agents; Biofilms; Candida; Candida albicans; Candida glabrata; Doxepin; Drug Repositioning; Drug Synergism; Fungal Proteins; Gene Expression Regulation, Fungal; Humans; Hyphae; Imipramine; Inactivation, Metabolic; Microsomes, Liver; Nortriptyline; Plankton | 2018 |
Supramolecular microextraction combined with paper spray ionization mass spectrometry for sensitive determination of tricyclic antidepressants in urine.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Doxepin; Humans; Imipramine; Liquid Phase Microextraction; Macromolecular Substances; Mass Spectrometry; Molecular Structure; Nortriptyline; Paper | 2020 |
β-Cyclodextrin Inclusion Complexation With Tricyclic Antidepressants Desipramine and Imipramine: A Structural Chemistry Perspective.
Topics: Antidepressive Agents, Tricyclic; beta-Cyclodextrins; Desipramine; Imipramine; Nortriptyline | 2020 |
Effects of the LC mobile phase in vacuum differential mobility spectrometry-mass spectrometry for the selective analysis of antidepressant drugs in human plasma.
Topics: Acetonitriles; Amitriptyline; Antidepressive Agents; Desipramine; Humans; Imipramine; Maprotiline; Mass Spectrometry; Methanol; Nortriptyline; Reproducibility of Results; Spectrum Analysis; Vacuum; Venlafaxine Hydrochloride | 2022 |
On-Chip Electromembrane Surrounded Solid Phase Microextraction for Determination of Tricyclic Antidepressants from Biological Fluids Using Poly(3,4-ethylenedioxythiophene)-Graphene Oxide Nanocomposite as a Fiber Coating.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Humans; Imipramine; Limit of Detection; Maprotiline; Nanocomposites; Nortriptyline; Reproducibility of Results; Sertraline; Solid Phase Microextraction | 2023 |