imipramine and norfluoxetine

imipramine has been researched along with norfluoxetine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (63.64)18.2507
2000's2 (18.18)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Sen, S; Sinha, N1
Bergstrom, RF; Lemberger, L; Peyton, AL1
Brøsen, K; Skjelbo, E1
Griffiths, HW; Marshall, EF; Tyrer, SP1
Asberg, M; Mårtensson, B; Montero, D; Siwers, B; Wgner, A1
el-Yazigi, A; Raines, DA1
Hashimoto, K; Minabe, Y; Narita, N; Tomitaka, S1
Hietala, J; Kuoppamäki, M; Laakso, A; Majasuo, H; Pälvimäki, EP; Roth, BL; Syvälahti, E1
Guo, B; He, MM; Li, C; Liu, H; Shen, H; Wang, L; Wrighton, SA1
Allen, KE; Babu, KN; Hanson, KL; Kunze, KL; Nelson, WL; VandenBrink, BM1

Other Studies

11 other study(ies) available for imipramine and norfluoxetine

ArticleYear
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Quantification and mechanism of the fluoxetine and tricyclic antidepressant interaction.
    Clinical pharmacology and therapeutics, 1992, Volume: 51, Issue:3

    Topics: Adult; Desipramine; Drug Evaluation; Drug Interactions; Fluoxetine; Humans; Imipramine; Male; Middle Aged

1992
Fluoxetine and norfluoxetine are potent inhibitors of P450IID6--the source of the sparteine/debrisoquine oxidation polymorphism.
    British journal of clinical pharmacology, 1991, Volume: 32, Issue:1

    Topics: Fluoxetine; Humans; Imipramine; Microsomes, Liver; Polymorphism, Genetic

1991
The relationship between response to fluoxetine, plasma drug levels, imipramine binding to platelet membranes and whole-blood 5-HT.
    Progress in neuro-psychopharmacology & biological psychiatry, 1990, Volume: 14, Issue:5

    Topics: Biomarkers; Biotransformation; Blood Platelets; Carrier Proteins; Cell Membrane; Depressive Disorder; Dexamethasone; Fluoxetine; Humans; Hydrocortisone; Imipramine; Receptors, Drug; Receptors, Neurotransmitter; Serotonin

1990
Effects of fluoxetine treatment of platelet 3H-imipramine binding, 5-HT uptake and 5-HT content in major depressive disorder.
    Journal of affective disorders, 1990, Volume: 20, Issue:2

    Topics: Adult; Aged; Blood Platelets; Carrier Proteins; Depressive Disorder; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Receptors, Drug; Receptors, Neurotransmitter; Serotonin

1990
Concurrent liquid chromatographic measurement of fluoxetine, amitriptyline, imipramine, and their active metabolites norfluoxetine, nortriptyline, and desipramine in plasma.
    Therapeutic drug monitoring, 1993, Volume: 15, Issue:4

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Desipramine; Fluoxetine; Humans; Imipramine; Indicators and Reagents; Nortriptyline; Spectrophotometry, Ultraviolet

1993
Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain.
    European journal of pharmacology, 1996, Jun-20, Volume: 307, Issue:1

    Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Brain; Desipramine; Fluoxetine; Imipramine; Male; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Selective Serotonin Reuptake Inhibitors; Stereoisomerism

1996
Interactions of selective serotonin reuptake inhibitors with the serotonin 5-HT2c receptor.
    Psychopharmacology, 1996, Volume: 126, Issue:3

    Topics: Animals; Antidepressive Agents, Tricyclic; Choroid Plexus; Citalopram; Fluoxetine; Imipramine; Male; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors

1996
Comparative metabolic capabilities and inhibitory profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:8

    Topics: Atomoxetine Hydrochloride; Cocaine; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Debrisoquin; Dextromethorphan; Enzyme Inhibitors; Ethanolamines; Fluoxetine; Humans; Hydroxylation; Imipramine; Kinetics; Microsomes; Molecular Structure; Nortriptyline; Polymorphism, Single Nucleotide; Propylamines; Quinidine; Recombinant Proteins; Thioridazine; Tramadol

2007
Sequential metabolism of secondary alkyl amines to metabolic-intermediate complexes: opposing roles for the secondary hydroxylamine and primary amine metabolites of desipramine, (s)-fluoxetine, and N-desmethyldiltiazem.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:6

    Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Desipramine; Diltiazem; Fluoxetine; Humans; Hydroxylamine; Hydroxylamines; Hydroxylation; Imipramine; Microsomes, Liver; Oxidoreductases, N-Demethylating; Steroid 16-alpha-Hydroxylase

2010