imipramine and nadp

imipramine has been researched along with nadp in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199016 (69.57)18.7374
1990's5 (21.74)18.2507
2000's1 (4.35)29.6817
2010's1 (4.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iwasaki, K; Kato, R; Noguchi, H1
Kato, R; Sugiura, M1
Grudin, R; Moldèus, P; Orrenius, S; Vadi, H1
Kappus, H; Remmer, H1
Kitamura, S; Mishima, HK; Nikaido, H; Shimada, S; Tatsumi, K1
Bellward, GD; Morgan, RG; Szombathy, VH1
Illing, HP; Kunke, S; Netter, KJ1
Bickel, MH; Gigon, PL1
Clark, B1
Gigon, PL; Gillette, JR; Gram, TE2
Gillette, JR; Hamrick, M; Sasame, H; Stripp, B; Zampaglione, N1
Bickel, MH1
Gillette, JR; Hamrick, M; Stripp, B; Zampaglione, N1
Oates, JA; Shand, DG1
Bhagwat, SV; Bhamre, S; Boyd, MR; Ravindranath, V1
Brøsen, K; Nielsen, KK; Skjelbo, E1
Kitamura, S; Tatsumi, K1
Itoh, K; Itoh, S; Kamataki, T; Kubo, A1
Inoue, N; Kamio, H; Kitamura, S; Ohta, S; Tatsumi, K; Terada, A1
Kitamura, S; Ohta, S; Sugihara, K; Takekawa, K1
CAMPAGNOLLE, A; POUGETOUX, J; VIADER, A1
Chen, SQ; Hu, HH; Jiang, HD; Kong, LM; Qian, MR; Xu, SY; Yu, LS; Zeng, S1

Other Studies

23 other study(ies) available for imipramine and nadp

ArticleYear
Stimulatory effect of FMN and methyl viologen on cytochrome P-450 dependent reduction of tertiary amine N-oxide.
    Biochemical and biophysical research communications, 1976, Sep-07, Volume: 72, Issue:1

    Topics: Amines; Animals; Cytochrome P-450 Enzyme System; Flavin Mononucleotide; Imipramine; Kinetics; Male; Microsomes, Liver; NADP; Oxides; Paraquat; Rats; Xanthine Oxidase

1976
Reduction of tertiary amine N-oxides by rat liver mitochondria.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 200, Issue:1

    Topics: Adenosine Triphosphate; Amines; Aniline Compounds; Animals; Antimycin A; Benzothiazoles; Carbon Monoxide; Citric Acid Cycle; Cyanides; Dicarboxylic Acids; Digitonin; Imipramine; In Vitro Techniques; Male; Mitochondria, Liver; NAD; NADP; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Oxygen; Phenobarbital; Piperazines; Rats; Rotenone; Thiazoles; Tricarboxylic Acids

1977
Drug metabolism in isolated rat liver cells.
    Advances in experimental medicine and biology, 1975, Volume: 58, Issue:00

    Topics: Alprenolol; Animals; Biotransformation; Carbon Monoxide; Cells, Cultured; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Fasting; Glucose; Glucuronates; Imipramine; Lactates; Liver; Methods; Metyrapone; NADP; Oxidation-Reduction; Phenobarbital; Proadifen; Protein Binding; Rats; Rotenone; Spectrum Analysis; Temperature; Tritium

1975
Irreversible protein binding of [14-C]imipramine with rat and human liver microsomes.
    Biochemical pharmacology, 1975, May-15, Volume: 24, Issue:10

    Topics: Animals; Carbon Monoxide; Cattle; Cytochrome P-450 Enzyme Inhibitors; Epoxide Hydrolases; Humans; Imipramine; In Vitro Techniques; Male; Microsomes, Liver; NADP; Proadifen; Protein Binding; Rats; Rifampin; Serum Albumin, Bovine; Sulfhydryl Compounds; Time Factors

1975
Metabolism of drugs in the eye. Menadione-dependent reduction of tertiary amine N-oxide by preparations from bovine ocular tissues.
    Current eye research, 1989, Volume: 8, Issue:12

    Topics: Animals; Cattle; Ciliary Body; Cytosol; Eye; Imipramine; Microsomes; NADP; Oxidation-Reduction; Oxidoreductases; Quinone Reductases; Vitamin K

1989
The effects of pretreatment of mice with norethindrone on the metabolism of 14C-imipramine by the liver microsomal drug-metabolizing enzymes.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:1

    Topics: Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Cobalt; Cytochrome c Group; Cytochrome Reductases; Dealkylation; Desipramine; Female; Hydrogen-Ion Concentration; Hydroxylation; Imipramine; Methylcholanthrene; Mice; Microsomes, Liver; NADP; Norethindrone; Oxides; Phenobarbital; Proadifen; Time Factors

1974
On the spectral intermediate at 440 nm formed during mixed function substrate oxidation.
    Biochemical pharmacology, 1974, Sep-15, Volume: 23, Issue:18

    Topics: Acetanilides; Aniline Compounds; Animals; Barbiturates; Cytochrome P-450 Enzyme System; Desipramine; Imipramine; In Vitro Techniques; Kinetics; Male; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Pentobarbital; Proadifen; Protein Binding; Rats; Spectrophotometry, Ultraviolet

1974
Metabolic interconversions and binding of imipramine, imipramine-N-oxide, and desmethylimipramine in rat liver slices.
    Xenobiotica; the fate of foreign compounds in biological systems, 1971, Volume: 1, Issue:6

    Topics: Animals; Cytosol; Dealkylation; Desipramine; Female; Imipramine; In Vitro Techniques; Liver; Male; Microsomes, Liver; NADP; Nitrogen Oxides; Oxidation-Reduction; Phenobarbital; Protein Binding; Rats; Sex Factors; Temperature; Time Factors

1971
The in vitro inhibition of the N-demethylation of pethidine by phenelzine (Phenethylhydrazine).
    Biochemical pharmacology, 1967, Volume: 16, Issue:12

    Topics: Alkaline Phosphatase; Animals; Cytochromes; Electron Transport; Esterases; Imipramine; Kinetics; Liver; Male; Meperidine; Microsomes; NADP; Oxidoreductases; Phenelzine; Rats

1967
Effect of drug substrates on the reduction of hepatic microsomal cytochrome P-450 by NADPH.
    Biochemical and biophysical research communications, 1968, May-23, Volume: 31, Issue:4

    Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; Kinetics; Liver; Male; Microsomes; Morphine; NADP; Niacinamide; Oxidation-Reduction; Pigments, Biological; Proadifen; Rats; Sex Factors; Spectrophotometry; Transferases

1968
Studies on the rate of reduction of hepatic microsomal cytochrome P-450 by reduced nicotinamide adenine dinucleotide phosphate: effect of drug substrates.
    Molecular pharmacology, 1969, Volume: 5, Issue:2

    Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Proadifen; Rats; Sex Factors; Spectrophotometry; Time Factors; Valerates

1969
Studies of the stoichiometric relationships between the oxidation of drugs and the oxidation of reduced pyridine nucleotides by liver microsomal enzymes.
    Chemico-biological interactions, 1971, Volume: 3, Issue:4

    Topics: Adenine Nucleotides; Aminopyrine; Cytochromes; Hexobarbital; Imipramine; Microsomes, Liver; Morphinans; NADP; Nucleotides; Oxidation-Reduction; Pharmaceutical Preparations; Pyridines

1971
Liver metabolic reactions: tertiary amine N-dealkylation, tertiary amine N-oxidation, N-oxide reduction, and N-oxide N-dealkylation. I. Tricyclic tertiary amine drugs.
    Archives of biochemistry and biophysics, 1972, Volume: 148, Issue:1

    Topics: Amitriptyline; Animals; Carbon Isotopes; Carbon Monoxide; Chlorpromazine; Cyclic N-Oxides; Cytochromes; Dealkylation; Desipramine; Horses; Imipramine; Kinetics; Liver; Male; NADP; Organ Specificity; Oxidation-Reduction; Proadifen; Rats; Species Specificity; Subcellular Fractions; Swine; Tetrazolium Salts

1972
An approach measurement of the stoichiometric relationship between hepatic microsomal drug metabolism and the oxidation of reduced nicotinamide adenine dinucleotide phosphate.
    Molecular pharmacology, 1972, Volume: 8, Issue:2

    Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Benzyl Compounds; Chlorine; Dealkylation; Ethylamines; Hexobarbital; Imipramine; Male; Methylamines; Microsomes, Liver; Morphine; NADP; Oxidation-Reduction; Pharmaceutical Preparations; Rats

1972
Metabolism of propranolol by rat liver microsomes and its inhibition by phenothiazine and tricyclic antidepressant drugs.
    Biochemical pharmacology, 1971, Volume: 20, Issue:7

    Topics: Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Desipramine; Imipramine; Kinetics; Liver; Male; Metabolism; Microsomes, Liver; NAD; NADP; Nitrogen; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Propranolol; Rats; Subcellular Fractions; Trifluoperazine; Triflupromazine

1971
Further characterization of rat brain flavin-containing monooxygenase. Metabolism of imipramine to its N-oxide.
    Biochemical pharmacology, 1996, Jun-14, Volume: 51, Issue:11

    Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Detergents; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Imipramine; Kinetics; Microsomes; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygenases; Rabbits; Rats; Rats, Wistar; Sodium Dodecyl Sulfate; Temperature

1996
Imipramine: a model drug for P450 research.
    Methods in enzymology, 1996, Volume: 272

    Topics: Antidepressive Agents, Tricyclic; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Humans; Imipramine; In Vitro Techniques; Microsomes, Liver; Models, Biological; NADP

1996
Menadione-dependent reduction of tertiary amine N-oxide by rat liver cytosol.
    Biochemistry and molecular biology international, 1997, Volume: 42, Issue:2

    Topics: Animals; Arsenites; Carbon Monoxide; Catalase; Cytosol; Dicumarol; Hemin; Hemoglobins; Imipramine; Liver; Male; Myoglobin; NAD; NADP; Oxidation-Reduction; Potassium Cyanide; Rats; Rats, Wistar; Sodium Compounds; Vitamin K

1997
Determination of FAD-binding domain in flavin-containing monooxygenase 1 (FMO1).
    Archives of biochemistry and biophysics, 1997, Sep-15, Volume: 345, Issue:2

    Topics: Animals; Binding Sites; Flavin-Adenine Dinucleotide; Glycine; Imipramine; Kinetics; Liver; Microsomes; Mutagenesis, Site-Directed; NADP; Oxygenases; Rats; Recombinant Proteins; Saccharomyces cerevisiae; Thioamides

1997
Quinone-dependent tertiary amine N-oxide reduction in rat blood.
    Biological & pharmaceutical bulletin, 1998, Volume: 21, Issue:12

    Topics: Animals; Antidepressive Agents, Tricyclic; Heme; Imipramine; In Vitro Techniques; Liver; Male; NAD(P)H Dehydrogenase (Quinone); NADP; Oxidation-Reduction; Rats; Rats, Wistar; Time Factors

1998
Non-enzymatic reduction of aliphatic tertiary amine N-oxides mediated by the haem moiety of cytochrome P450.
    Xenobiotica; the fate of foreign compounds in biological systems, 2001, Volume: 31, Issue:1

    Topics: Amines; Animals; Catalysis; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Flavins; Heme; Imipramine; In Vitro Techniques; Male; Microsomes, Liver; NADP; Niacinamide; Oxidation-Reduction; Oxidoreductases; Rats; Rats, Sprague-Dawley; Strychnine

2001
[PROBLEMS RAISED BY THE PROLONGED USE OF NEUROLEPTICS AND ANTIDEPRESSANTS. (SIGNIFICANCE OF THE STUDY OF NEUROMUSCULAR EXCITABILITY AND THE RATIO NAPL-KGB)].
    Annales medico-psychologiques, 1964, Volume: 122

    Topics: Adenosine Triphosphate; Antidepressive Agents; Antipsychotic Agents; Blood; Central Nervous System; Chlorpromazine; Imipramine; Ion Exchange; Mental Disorders; Metabolism; NADP; Nervous System; Phenothiazines; Potassium; Psychopharmacology; Psychoses, Alcoholic; Psychotic Disorders; Schizophrenia; Sodium; Toxicology; Tranquilizing Agents

1964
Comparison of catalytical activity and stereoselectivity between the recombinant human cytochrome P450 2D6.1 and 2D6.10.
    Die Pharmazie, 2012, Volume: 67, Issue:5

    Topics: Adrenergic beta-Antagonists; Algorithms; Alleles; Antidepressive Agents, Tricyclic; Baculoviridae; Catalysis; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Data Interpretation, Statistical; Humans; Hydroxylation; Imipramine; Isoenzymes; Kinetics; NADP; Propranolol; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Substrate Specificity

2012