imipramine has been researched along with morphine in 131 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 82 (62.60) | 18.7374 |
1990's | 11 (8.40) | 18.2507 |
2000's | 25 (19.08) | 29.6817 |
2010's | 13 (9.92) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
Anderson, VB; Geyer, HM; Kruse, H; Ong, HH; Profitt, JA; Spaulding, TC; Wilker, JC | 1 |
Strassburg, CP; Tukey, RH | 1 |
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
Duffy, EM; Jorgensen, WL | 1 |
Topliss, JG; Yoshida, F | 1 |
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
Chang, TK; Ensom, MH; Kiang, TK | 1 |
Nagashima, R; Nishikawa, T; Tobita, M | 1 |
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Campillo, NE; Guerra, A; Páez, JA | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Fitzsimons, JT; Loker, JE; Smith, PA; Walker, RJ | 1 |
Bissada, NK; Finkbeiner, AE; Welch, LT | 1 |
Bates, A; Shuster, L; Yu, G | 1 |
Kelder, D; Ross, SB | 1 |
Bhattacharya, SK | 1 |
Pickens, R; Thompson, T | 1 |
Poignant, JC; Rismondo, N | 1 |
Celsen, B; Huppertz, A; Kuschinsky, K | 1 |
Kunihara, M; Nakano, M; Ohyama, M | 1 |
Ambrogi, F; Cassano, GB; Marazziti, D; Rotondo, A | 1 |
Alvarez, L; Asher, K; Bergman, SA; Thut, PD; Wynn, RL | 1 |
Gastmeier, K; Hass, M; Kuteifan, K; Schott, H | 1 |
Kuschinsky, K; Wenzel, J | 1 |
Berman, EF; Fujimoto, JM; Schaus, P | 1 |
Reny-Palasse, V; Rips, R | 1 |
Abbiati, G; Ibba, M; Schiavi, S; Testa, R | 1 |
Besson, JM; Butler, SH; Godefroy, F; Weil-Fugazza, J | 1 |
Bickel, MH; Di Francesco, C | 1 |
Hancock, S; Picker, M; Poling, A; Wallace, S | 1 |
Dews, PB; Lehr, E; Morse, WH | 1 |
Bell, S; Jhamandas, K; Sutak, M | 1 |
Schuster, CR; Wilson, MC | 1 |
Goldberg, SR; Hoffmeister, F | 1 |
Colhoun, E; Dubas, T; Lundy, P; Parker, JM | 1 |
Carroll, BJ; Sharp, PT | 1 |
Ahtee, L; Kääriäinen, I | 1 |
Greengard, P; Quinn, GP; Reid, MB | 1 |
Hartmann, E | 1 |
Kaniike, K; Kurogochi, Y | 1 |
Cater, BR; Chapman, D; Hawes, SM; Saville, J | 1 |
Mennear, JH; Rudzik, AD | 1 |
Dhalla, NS | 1 |
Gigon, PL; Gillette, JR; Gram, TE | 1 |
Mattila, MJ; Saarnivaara, L | 2 |
Saarnivaara, L | 1 |
Oldendorf, WH | 1 |
Gillette, JR; Hamrick, M; Stripp, B; Zampaglione, N | 1 |
Dubileĭ, PV; Urazaeva, ZV | 1 |
Kowa, Y; Nakama, M; Ochiai, T | 1 |
Kocher, R; Rohrer, G | 1 |
Männistö, PT; Saarnivaara, L | 1 |
Kaneto, H; Koida, M; Tsuchie, F | 1 |
Mann, WA; Ridley, PT | 1 |
McMillan, DE | 1 |
Gershon, S; Sanghvi, I | 1 |
Zakusov, VV | 1 |
Abe, A; Fujimura, H; Go, K; Hayashi, M; Tsurumi, K | 1 |
Knoll, J; Zsilla, G | 1 |
Ciofalo, FR | 1 |
Baden, MM; Valanju, NN; Valanju, SN; Verma, SK | 1 |
Domino, EF; Wilson, AE | 1 |
Delini-Stula, A | 1 |
Burov, IuV; Kurochkin, IG | 2 |
Bhalla, TN; Bhargava, KP; Kohli, RP; Sinha, JN | 1 |
Drew, WG; Fink, M; White, RP | 1 |
Kleinrok, Z; Langwiński, R; Ozimek, H | 1 |
Kreppel, E | 1 |
Bauer, BG; Brodie, DA; Lotti, VJ | 1 |
Imamura, H; Maruyama, Y; Nakanishi, M | 1 |
Eidelberg, E; Schwartz, AS | 1 |
Burov, IuV | 1 |
Senault, B | 1 |
Katz, MH; Krop, S; Yen, HC | 1 |
Kiplinger, GF | 1 |
Laplace, JP; Ruckebusch, Y | 1 |
Ibrahim, I; Sulman, FG; Weller, CP | 1 |
Nott, MW | 1 |
Banaru, A; Chiosa, L; Dumitrescu, S | 1 |
Winter, D | 1 |
Mulé, SJ | 1 |
Blumberg, AG; Heaton, AM | 1 |
Haas, H; Jantos, W | 1 |
Sharman, DF | 1 |
Collins, RJ; Simonton, VR | 1 |
Pálosi, E; Szporny, L | 1 |
Scuvée-Moreau, JJ; Svensson, TH | 1 |
Frischknecht, HR; Sieber, B; Waser, PG | 1 |
Kato, S; Yanagita, T | 1 |
Gibert-Rahola, J; Maldonado, R; Mico, JA; Roques, BP; Tejedor-Real, P | 1 |
Fukase, H; Fukuzaki, K; Koja, T; Lukas, SE; Nagata, R | 1 |
Kuribara, H | 1 |
Atcheson, R; Lambert, DG; Rowbotham, DJ | 1 |
Mendez, M; Miranda, HF; Pinardi, G; Sierralta, F | 1 |
Huang, NY; Layer, RT; Skolnick, P; Strakhova, M | 1 |
Sahebgharani, M; Valizadeh, S; Zarrindast, M | 1 |
Sahebgharani, M; Shaverdian, S; Zarrindast, MR | 1 |
Sahebgharani, M; Zarrindast, M | 1 |
Burchell, B; Riley, RJ; Soars, MG | 1 |
Bruins Slot, LA; Colpaert, FC; Koek, W; Ribet, JP; Tarayre, JP | 1 |
Adl, M; Bahreini, T; Zarrindast, MR | 1 |
Assié, MB; Bardin, L; Carilla-Durand, E; Colpaert, FC; Cosi, C; Koek, W; Pauwels, PJ; Tarayre, JP; Vacher, B; Wiesenfeld-Hallin, Z; Xu, XJ | 1 |
Torkaman-Boutorabi, A; Zarrindast, MR | 1 |
JACOBSEN, P | 1 |
BROSSARD, M; QUASTEL, JH | 1 |
ENDROECZI, E; KORANYI, L; LISSAK, K | 1 |
ASKEW, BM | 1 |
KOBAYASHI, T | 1 |
France, CP; McMahon, LR; Sell, SL | 1 |
Gibert-Rahola, J; Gutiérrez, M; Micó, JA; Ortega-Alvaro, A | 1 |
Farazifard, R; Javan, M; Safarpour, F; Sheibani, V | 1 |
Fukazawa, Y; Kiguchi, N; Kishioka, S; Kobayashi, Y; Maeda, T; Ozaki, M; Saika, F | 1 |
Cao, J; Mao, RR; Tian, M; Wang, LP; Xu, L; Zhou, QX | 1 |
Ando, A; Higashi, E; Iwano, S; Miyamoto, Y; Murayama, N; Yamazaki, H | 1 |
Harada, S; Matsuura, W; Tokuyama, S | 1 |
Guo, D; Guo, J; Huang, S; Li, Q; Polli, JE; Shu, Y; Xiong, Z; Ye, Z; Zhang, W; Zhou, H; Zhu, P | 1 |
6 review(s) available for imipramine and morphine
Article | Year |
---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Uropharmacology: X. Central nervous system stimulants and depressants.
Topics: Amphetamines; Anesthetics; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Baclofen; Benzodiazepines; Central Nervous System Agents; Chloral Hydrate; Humans; Imipramine; Levodopa; Meperidine; Meprobamate; Morphine; Nortriptyline; Paraldehyde; Phenothiazines; Phenytoin; Picrotoxin; Reserpine; Strychnine; Urinary Tract | 1979 |
An experimental analysis of behavioral factors in drug dependence.
Topics: Administration, Oral; Alcoholism; Amphetamine; Animals; Behavior, Animal; Cannabis; Chlorpromazine; Cocaine; Dextroamphetamine; Drinking Behavior; Dronabinol; Ethanol; Humans; Imipramine; Injections, Intravenous; Macaca mulatta; Morphine; Pentobarbital; Reinforcement Schedule; Secobarbital; Social Environment; Substance-Related Disorders; Time Factors | 1975 |
Pharmacological studies of sleep and dreaming: chemical and clinical relationships.
Topics: Amitriptyline; Amphetamine; Antidepressive Agents; Atropine; Chloralose; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Diazepam; Diphenhydramine; Dreams; Glutethimide; Humans; Hypnotics and Sedatives; Imipramine; Lysergic Acid Diethylamide; Meprobamate; Methaqualone; Morphine; Nialamide; Pentobarbital; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tranylcypromine; Triiodothyronine; Tryptophan | 1969 |
1 trial(s) available for imipramine and morphine
Article | Year |
---|---|
[Treatment of severe chronic pains with a combination of thymoleptics and neuroleptics (author's transl)].
Topics: Adult; Antidepressive Agents; Atropine; Chlorpromazine; Clinical Trials as Topic; Clomipramine; Drug Combinations; Female; Haloperidol; Humans; Imipramine; Male; Methotrimeprazine; Middle Aged; Morphine; Neoplasms; Pain; Papaverine; Tranquilizing Agents | 1974 |
124 other study(ies) available for imipramine and morphine
Article | Year |
---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Tricyclics with analgesic and antidepressant activity. 1. [[(Alkylamino)ethyl]thio]dibenz[b,f]oxepins and 10,11-dihydro derivatives.
Topics: Amphetamine; Analgesics; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chemical Phenomena; Chemistry; Dibenzoxepins; Mice | 1980 |
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
5-hydroxytryptamine as a possible inhibitory neurotransmitter in the central nervous system of the leech, Haemopis sanguisuga.
Topics: Central Nervous System; Ganglia; Imipramine; Leeches; Microscopy, Electron; Microscopy, Fluorescence; Morphine; Neurons; Serotonin | 1975 |
Sensitization to cocaine stimulation in mice.
Topics: Animals; Brain Chemistry; Cocaine; Cycloheximide; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Female; Imipramine; Male; Mice; Mice, Inbred A; Mice, Inbred BALB C; Mice, Inbred C57BL; Morphine; Motor Activity; Norepinephrine; Reserpine; Species Specificity; Stimulation, Chemical; Time Factors | 1977 |
Release of 3H-noradrenaline from the rat vas deferens under various in vitro conditions.
Topics: Aminobenzoates; Amphetamine; Anesthetics, Local; Animals; Calcium; Choline; Desipramine; Dose-Response Relationship, Drug; Imipramine; Male; Morphine; Norepinephrine; Potassium; Rats; Reserpine; Sodium; Vas Deferens; Veratridine | 1979 |
Imipramine-induced potentiation of morphine analgesia in the rat: role of brain monoamines.
Topics: Analgesia; Animals; Biogenic Amines; Drug Synergism; Female; Imipramine; Male; Morphine; Rats | 1978 |
[Influence of the administration of psychopharmacological compounds on the take up time of an alimentary material in the hamster and a study of the associated behaviour (author's transl)].
Topics: Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Clonidine; Cricetinae; Dextroamphetamine; Diazepam; Feeding Behavior; Fenfluramine; Humans; Imipramine; Male; Meprobamate; Mesocricetus; Morphine; Motor Activity; Phenobarbital; Piribedil; Psychotropic Drugs; Stereotyped Behavior; Sulpiride; Time Factors | 1975 |
Studies on dopamine kinetics in rat brain tissue under the influence of morphine.
Topics: Animals; Apomorphine; Corpus Striatum; Dextroamphetamine; Dopamine; Humans; Imipramine; In Vitro Techniques; Kinetics; Morphine; Morphine Dependence; Naloxone; Potassium; Rats; Sensory Receptor Cells; Stereotyped Behavior | 1975 |
Central monoaminergic mechanisms in mice and analgesic activity of spiradoline mesylate, a selective kappa-opioid receptor agonist.
Topics: Analgesics; Animals; Brain; Clomipramine; Desipramine; Fenclonine; Imipramine; Male; Mice; Mice, Inbred ICR; Morphine; Norepinephrine; Phenoxybenzamine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Reserpine; Serotonin | 1992 |
Analgesia by nefopam: does it act through serotonin?
Topics: Analgesia; Blood Platelets; Desipramine; Dose-Response Relationship, Drug; Humans; Imipramine; Morphine; Nefopam; Orphenadrine; Serotonin Antagonists | 1991 |
Imipramine-fentanyl antinociception in a rabbit tooth pulp model.
Topics: Analgesics; Animals; Carbon Dioxide; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Electric Stimulation; Female; Fentanyl; Imipramine; Injections, Intravenous; Kinetics; Male; Morphine; Naloxone; Nociceptors; Rabbits; Respiration | 1991 |
[Pain therapy for urologic cancer patients at the Potsdam district hospital--initial results].
Topics: Aged; Amitriptyline; Analgesics; Analgesics, Opioid; Aspirin; Carbamazepine; Codeine; Dipyrone; Drug Therapy, Combination; Haloperidol; Humans; Imipramine; Indomethacin; Meperidine; Morphine; Pain; Pain Measurement; Prospective Studies; Urologic Neoplasms | 1990 |
Interactions between imipramine and morphine on motility in rats: possible relation to antidepressant effects?
Topics: Animals; Behavior, Animal; Depressive Disorder; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Imipramine; Male; Morphine; Motor Activity; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1990 |
Comparison of the inhibition of biliary excretion produced by certain inducing agents including 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: Animals; Bile; Carbon Radioisotopes; Chlordecone; Dioxins; Drug Interactions; Imipramine; Injections, Intraperitoneal; Insecticides; Male; Mirex; Morphine; Ouabain; Pentobarbital; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred Strains; Tritium; Urethane | 1986 |
Potentiation by TRH of the effect of imipramine on the forced-swimming test.
Topics: Animals; Drug Synergism; Drug Tolerance; Imipramine; Male; Mice; Morphine; Naloxone; Phenoxybenzamine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha; Receptors, Opioid; Swimming; Thyrotropin-Releasing Hormone; Yohimbine | 1985 |
Effects of oral administration of nortriptyline, imipramine and citalopram on morphine hot-plate and tail-immersion analgesia in rats.
Topics: Analgesia; Animals; Antidepressive Agents; Citalopram; Drug Interactions; Imipramine; Male; Morphine; Nortriptyline; Propylamines; Rats; Reaction Time | 1987 |
Do acute or chronic tricyclic antidepressants modify morphine antinociception in arthritic rats?
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Arthritis; Arthritis, Experimental; Drug Synergism; Drug Therapy, Combination; Imipramine; Male; Morphine; Nociceptors; Pain; Rats; Rats, Inbred Strains; Sensory Thresholds; Vocalization, Animal | 1986 |
Uptake in vitro of lipophilic model compounds into adipose tissue preparations and lipids.
Topics: Adipose Tissue; Animals; Carbon Radioisotopes; Chlorpromazine; Glutethimide; Half-Life; Imipramine; In Vitro Techniques; Kinetics; Male; Morphine; Polychlorinated Biphenyls; Rats; Scintillation Counting; Thiopental | 1985 |
Discriminative stimulus properties of valproic acid in the pigeon.
Topics: Animals; Anticonvulsants; Columbidae; Dextroamphetamine; Discrimination Learning; Generalization, Psychological; Imipramine; Morphine; Pentylenetetrazole; Valproic Acid | 1985 |
Effects of drugs on schedule-controlled running of mice in a circular runway.
Topics: Amphetamine; Animals; Chlordiazepoxide; Chlorpromazine; Clozapine; Female; Food Deprivation; Imipramine; Mice; Morphine; Motor Activity; Pentobarbital; Reinforcement Schedule | 1985 |
Modification of precipitated morphine withdrawal syndrome by drugs affecting cholinergic mechanisms.
Topics: Animals; Atropine; Autonomic Nervous System; Diphenhydramine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Imipramine; Mecamylamine; Morphine; Morphine Dependence; Naloxone; Neurotransmitter Agents; Physostigmine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Substance Withdrawal Syndrome; Synaptic Transmission; Tolazoline | 1973 |
The effects of stimulants and depressants on cocaine self-administration behavior in the rhesus monkey.
Topics: Animals; Cocaine; Exploratory Behavior; Grooming; Haplorhini; Imipramine; Locomotion; Macaca; Male; Morphine; Motor Activity; Pentobarbital; Phenmetrazine; Self Medication; Trifluoperazine | 1973 |
A comparison of chlorpromazine, imipramine, morphine and d-amphetamine self-administration in cocaine-dependent rhesus monkeys.
Topics: Animals; Behavior, Animal; Chlorpromazine; Cocaine; Dextroamphetamine; Dose-Response Relationship, Drug; Haplorhini; Humans; Imipramine; Macaca; Morphine; Self Stimulation; Substance-Related Disorders | 1973 |
Investigation of mechanisms involved in toxic effects of narcotic analgesics.
Topics: Analgesics; Animals; Brain; Brain Chemistry; Catecholamines; Dextropropoxyphene; Drug Interactions; Female; Fenclonine; Heroin; Imipramine; Lethal Dose 50; Morphine; Naloxone; Narcotics; Norepinephrine; Pargyline; Rats; Reserpine; Tranylcypromine; Tyrosine | 1972 |
Monoamine mediation of the morphine-induced activation of mice.
Topics: 5-Hydroxytryptophan; Aniline Compounds; Animals; Atropine; Chlorpromazine; Cinnamates; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Drug Synergism; Fenclonine; Haloperidol; Imipramine; Male; Methyltyrosines; Methysergide; Mice; Monoamine Oxidase Inhibitors; Morphine; Motor Activity; Nalorphine; Pargyline; Phenoxybenzamine; Phentolamine; Reserpine | 1972 |
5-hydroxytryptamine in platelets and brain of rabbits treated chronically with imipramine, morphine or methadone.
Topics: Animals; Blood Platelets; Brain Chemistry; Hydroxyindoleacetic Acid; Imipramine; Male; Methadone; Morphine; Rabbits; Serotonin; Time Factors | 1973 |
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine | 1966 |
[Effect of psychotropic drugs on the K + -dependent phosphatase activity in guinea pig brain microsomes].
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Chlordiazepoxide; Chlorpromazine; Desipramine; Diazepam; Guinea Pigs; Histamine; Hydroxyzine; Imipramine; Meprobamate; Microsomes; Morphine; Nialamide; Phenelzine; Phenobarbital; Phenoxybenzamine; Phosphoric Monoester Hydrolases; Pilocarpine; Potassium; Procaine; Reserpine; Tranquilizing Agents | 1972 |
Lipid phase transitions and drug interactions.
Topics: Amitriptyline; Binding Sites; Calorimetry; Desipramine; Electron Spin Resonance Spectroscopy; Imipramine; Kinetics; Magnetic Resonance Spectroscopy; Membranes, Artificial; Models, Biological; Molecular Conformation; Morphinans; Morphine; Nortriptyline; Palmitic Acids; Phosphatidylcholines; Structure-Activity Relationship; Temperature; Thermodynamics | 1974 |
Potentiation of the anticonvulsant action of acetazolamide.
Topics: Acetazolamide; Amphetamine; Animals; Anticonvulsants; Caffeine; Cocaine; Desipramine; Drug Synergism; Electric Stimulation; Electroshock; Ephedrine; Histamine H1 Antagonists; Imipramine; Isoproterenol; Male; Metaraminol; Mice; Morphine; Phenethylamines; Quaternary Ammonium Compounds; Seizures; Stress, Physiological; Tranylcypromine; Tyramine | 1966 |
Mechanisms of sympathomimetic effects of dichloroisoproterenol: comparison with tyramine, nicotine and norepinephrine.
Topics: Animals; Atropine; Cocaine; Diaphragm; Drug Antagonism; Ganglionic Blockers; Guanidines; Heart; Heart Atria; Hexamethonium Compounds; Imipramine; In Vitro Techniques; Iproniazid; Isoproterenol; Morphine; Nicotine; Norepinephrine; Pentolinium Tartrate; Phenoxybenzamine; Propranolol; Rats; Sympatholytics; Tranylcypromine; Tyramine | 1967 |
Effect of drug substrates on the reduction of hepatic microsomal cytochrome P-450 by NADPH.
Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; Kinetics; Liver; Male; Microsomes; Morphine; NADP; Niacinamide; Oxidation-Reduction; Pigments, Biological; Proadifen; Rats; Sex Factors; Spectrophotometry; Transferases | 1968 |
Modification by antihistaminic drugs of the morphine analgesia in rabbits.
Topics: Analgesia; Animals; Drug Synergism; Histamine H1 Antagonists; Imipramine; Morphine; Rabbits; Reserpine | 1968 |
Influence of some drugs on the accumulation of morphine in rabbit red cells in vitro.
Topics: Analgesia; Animals; Cyproheptadine; Diphenhydramine; Dopamine; Drug Synergism; Erythrocytes; Hemolysis; Histamine H1 Antagonists; Imipramine; In Vitro Techniques; Indomethacin; Isotonic Solutions; Male; Morphine; Norepinephrine; Phenothiazines; Pyrrolidines; Rabbits; Serotonin | 1969 |
Brain uptake of metabolites and drugs following carotid arterial injections.
Topics: Acetates; Amino Acids; Animals; Antipyrine; Ascorbic Acid; Aspirin; Barbiturates; Blood-Brain Barrier; Brain; Caffeine; Chloroquine; Cyanides; Ethanol; Imipramine; Lactates; Mescaline; Morphine; Neurotransmitter Agents; Nicotine; Penicillin G; Pharmaceutical Preparations; Phenytoin; Procaine; Pyruvates; Rats | 1971 |
An approach measurement of the stoichiometric relationship between hepatic microsomal drug metabolism and the oxidation of reduced nicotinamide adenine dinucleotide phosphate.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Benzyl Compounds; Chlorine; Dealkylation; Ethylamines; Hexobarbital; Imipramine; Male; Methylamines; Microsomes, Liver; Morphine; NADP; Oxidation-Reduction; Pharmaceutical Preparations; Rats | 1972 |
[Role of the lungs in the inactivation of serotonin].
Topics: Animals; Body Temperature; Cocaine; Cyanides; Imipramine; Iodoacetates; Lung; Lysergic Acid Diethylamide; Monoamine Oxidase Inhibitors; Morphine; Potassium; Rats; Serotonin; Time Factors | 1974 |
Effects of psychotropic drugs on emotional behavior: exploratory behavior of naive rats in holed open field.
Topics: Animals; Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Defecation; Diazepam; Emotions; Exploratory Behavior; Hallucinogens; Haloperidol; Imipramine; Male; Meprobamate; Mescaline; Methamphetamine; Methods; Morphine; Motor Activity; Perphenazine; Rats; Time Factors; Tranquilizing Agents | 1972 |
Effect of lithium on the analgesia caused by morphine and two antidepressants in mice.
Topics: Analgesia; Animals; Antidepressive Agents; Dibenzocycloheptenes; Imipramine; Lithium; Male; Mice; Morphine; Motor Activity; Postural Balance; Quinones; Time Factors | 1972 |
[Tolerance and physical dependence producing liability of doxepin].
Topics: Amitriptyline; Animals; Body Weight; Diazepam; Dibenzoxepins; Drug Resistance; Humans; Imipramine; Male; Mice; Morphine; Motor Activity; Phenobarbital; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders | 1972 |
Central antisecretory action of desmethylimipramine in the rat.
Topics: Animals; Central Nervous System; Chlorpromazine; Desipramine; Gastric Juice; Gastric Mucosa; Imipramine; Injections, Intravenous; Male; Morphine; Rats; Stomach | 1973 |
Drugs and punished responding. I. Rate-dependent effects under multiple schedules.
Topics: Animals; Chlordiazepoxide; Chlorpromazine; Columbidae; Conditioning, Operant; Dextroamphetamine; Diazepam; Dronabinol; Feeding Behavior; Imipramine; Male; Meprobamate; Mescaline; Morphine; Oxazepam; Pentobarbital; Psychopharmacology; Punishment; Reinforcement Schedule; Tetrabenazine | 1973 |
Rubidium and lithium: evaluation as antidepressant and anti-manic agents.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Drug Synergism; Imipramine; Lithium; Male; Mice; Morphine; Motor Activity; Photometry; Rubidium; Time Factors | 1973 |
[The effect tranquilizers and antidepressants on the summation of impulses of different modalities].
Topics: Animals; Auditory Perception; Central Nervous System; Chlordiazepoxide; Conditioning, Classical; Depression, Chemical; Diazepam; Imipramine; Morphine; Pain; Rats; Stimulation, Chemical; Thalamus; Visual Perception | 1973 |
[Anti-inflammatory and analgesic effects of benzodiazepine derivatives].
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzazepines; Capillary Permeability; Chlorpromazine; Drug Synergism; Edema; Female; Granuloma; Imipramine; Male; Mice; Morphine; Phenylbutazone; Pyrazoles; Pyrimidines; Rats | 1973 |
Possible mechanism of the low tolerance capacity of azidomorphine and azidocodeine.
Topics: Animals; Azides; Codeine; Culture Media; Dealkylation; Drug Tolerance; Imipramine; Lethal Dose 50; Liver; Male; Morphinans; Morphine; Oxidoreductases, N-Demethylating; Rats; Rats, Inbred Strains; Time Factors | 1974 |
Methadone inhibition of 3H-5-hydroxytryptamine uptake by synaptosomes.
Topics: Animals; Brain; Centrifugation, Density Gradient; Cold Temperature; Dinitrophenols; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Kinetics; Male; Methadone; Monoamine Oxidase Inhibitors; Morphine; Naloxone; Ouabain; Potassium Chloride; Rabbits; Serotonin; Serotonin Antagonists; Sucrose; Synaptosomes; Tritium | 1974 |
Comparison of tricyclic antidepressants in rabbits: antinociception and potentiation of the noradrenaline pressor responses.
Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Aorta; Blood Pressure; Chlorpromazine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Doxepin; Drug Synergism; Imipramine; In Vitro Techniques; Iprindole; Lithium; Morphine; Norepinephrine; Nortriptyline; Opipramol; Rabbits; Succinimides; Time Factors | 1974 |
Confirmed identification of biotransformed drugs of abuse in urine.
Topics: Amphetamine; Analgesics; Barbiturates; Biotransformation; Caffeine; Cannabis; Chromatography, Gas; Chromatography, Thin Layer; Codeine; Humans; Hydrogen-Ion Concentration; Imipramine; Indicators and Reagents; Methadone; Morphine; Nicotine; Pharmaceutical Preparations; Procaine; Skin; Spectrum Analysis; Substance-Related Disorders; Tranquilizing Agents | 1972 |
Psychotropic drug influences on brain acetylcholine utilization.
Topics: Acetylcholine; Animals; Antidepressive Agents; Brain; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Hemicholinium 3; Imipramine; Lysergic Acid Diethylamide; Male; Methotrimeprazine; Morphine; Pentobarbital; Phencyclidine; Rats; Rats, Inbred Strains; Scopolamine; Tranquilizing Agents | 1972 |
Drug-induced suppression of conditioned hyperthermic and conditioned avoidance behavior response in rats.
Topics: Animals; Avoidance Learning; Behavior, Animal; Chlorpromazine; Conditioning, Psychological; Fever; Imipramine; Morphine; Phentolamine; Rats; Thioridazine | 1971 |
[Effect of psychotropic drugs on the emotional behavior of cats caused by the administration of acetylcholine into the central grey matter].
Topics: Acetylcholine; Animals; Atropine; Behavior, Animal; Benactyzine; Cats; Chlordiazepoxide; Chlorpromazine; Haloperidol; Imipramine; Meprobamate; Morphine; Tranquilizing Agents; Trifluoperazine | 1971 |
Aconitine-induced writhing: a method for assessment of analgesic activity.
Topics: Aconitum; Analgesics; Animals; Aspirin; Behavior, Animal; Chlorpromazine; Imipramine; Mephenesin; Methaqualone; Methods; Mice; Morphine; Phenoxybenzamine; Phenylbutazone; Phenytoin; Sodium Salicylate | 1969 |
Neuropharmacological analysis of agonistic actions of cyclazocine in rabbits.
Topics: Analgesics; Animals; Azocines; Cyclazocine; Drug Synergism; Drug Tolerance; Electroencephalography; Female; Heroin; Imipramine; Male; Methamphetamine; Methods; Morphine; Motor Activity; Muscles; Narcotic Antagonists; Pentazocine; Physostigmine; Rats; Scopolamine; Stimulation, Chemical | 1969 |
[Influence of some psychotropic drugs upon the action of morphine, dolantine and aminophenazone in white mice].
Topics: Aminopyrine; Animals; Drug Antagonism; Drug Synergism; Female; Imipramine; Male; Mice; Morphine; Nialamide; Silicon; Time Factors | 1969 |
[Principles and risks of drug treatment of pain].
Topics: Aminopyrine; Analgesics; Antidepressive Agents; Antipyrine; Aspirin; Codeine; Dibenzazepines; Humans; Imipramine; Levallorphan; Levorphanol; Methadone; Morphine; Pain; Phenacetin; Phenylbutazone; Pyrazoles; Salicylamides; Salicylates; Sulfonic Acids | 1969 |
Drug effects on gastric secretion and stress gastric hemorrhage in the rat.
Topics: Animals; Atropine; Autonomic Agents; Brain; Cerebral Ventricles; Chlordiazepoxide; Chlorpromazine; Dimethyl Sulfoxide; Gastric Acidity Determination; Gastric Juice; Humans; Imidazoles; Imipramine; Injections, Intravenous; Morphine; Peptic Ulcer Hemorrhage; Psychophysiologic Disorders; Rats; Stress, Psychological; Vagotomy | 1970 |
[Studies on anti-inflammatory agents. II. Analgesic and anti-edematous activities of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6, 7-tetrahydrothieno (2,3-c)pyridine (Y-3642)].
Topics: Aminopyrine; Amphetamine; Analgesics; Animals; Anti-Inflammatory Agents; Edema; Imipramine; Male; Mice; Morphine; Pain; Papaverine; Phenylbutazone; Pyridines; Rats; Salicylates; Thiophenes | 1970 |
Role of biogenic amines in morphine dependence in the rat.
Topics: Animals; Brain; Dihydroxyphenylalanine; Dopamine; Female; Humans; Imipramine; Male; Methyltyrosines; Morphine; Nalorphine; Norepinephrine; Phenylalanine; Rats; Serotonin; Substance-Related Disorders; Thiocarbamates | 1970 |
[The appearance of threat and flight reactions evoked by stimulation of the anterior hypothalamus of cats against a background of psychotropic drug action].
Topics: Aggression; Animals; Benactyzine; Cats; Chlordiazepoxide; Chlorpromazine; Electric Stimulation; Escape Reaction; Haloperidol; Humans; Hypothalamus; Imipramine; Meprobamate; Morphine; Psychopharmacology; Trifluoperazine | 1970 |
[Intraspecific aggressive behavior induced by apomorphine in the rat].
Topics: Acepromazine; Age Factors; Aggression; Amitriptyline; Animals; Apomorphine; Atropine; Behavior, Animal; Caffeine; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Diazepam; Drug Antagonism; Electroshock; Environment; Haloperidol; Humans; Hydroxyzine; Imipramine; Male; Meprobamate; Morphine; Rats; Reserpine; Sex Factors; Sound; Species Specificity; Thiazines; Thioridazine | 1970 |
Effects of various drugs on 3,4-dihydroxyphenylalanine (DL-DOPA)-induced excitation (agressive behavior) in mice.
Topics: Aggression; Animals; Antidepressive Agents; Autonomic Agents; Behavior, Animal; Bretylium Compounds; Chlordiazepoxide; Chlorpromazine; Diazepam; Dihydroxyphenylalanine; Drug Antagonism; Haloperidol; Hexobarbital; Humans; Imipramine; Iproniazid; Male; Mice; Morphine; Oxazepam; Reserpine; Tranquilizing Agents; Tranylcypromine; Trifluoperazine | 1970 |
[Effect of psychotropic substances on the behavior of cats, induced by administration of acetylcholine into the hypothalamus].
Topics: Acetylcholine; Action Potentials; Amygdala; Animals; Atropine; Behavior, Animal; Benactyzine; Cats; Chlordiazepoxide; Chlorpromazine; Depression, Chemical; Electroencephalography; Haloperidol; Hostility; Hypothalamus; Imipramine; Meprobamate; Morphine; Reticular Formation; Stimulation, Chemical; Tranquilizing Agents; Trifluoperazine | 1971 |
The effects of drugs on the rate of development of fatigue in mice.
Topics: Amphetamine; Animals; Dextroamphetamine; Fatigue; Imipramine; Male; Methods; Mice; Morphine; Pentobarbital; Phenmetrazine; Stimulation, Chemical; Swimming | 1967 |
[Pharmacologic changes in feeding behavior: food intake and rumination in sheep].
Topics: Amphetamine; Animals; Apomorphine; Atropine; Behavior, Animal; Cerebral Cortex; Chlorpromazine; Digestion; Digitalis Glycosides; Eating; Imipramine; Iproniazid; Lanatosides; Mescaline; Methylphenidate; Morphine; Ouabain; Pentobarbital; Psychopharmacology; Reticulum; Rumen; Sheep; Theophylline | 1968 |
Analgesic profile of tranquillizers in multiple screening tests in mice.
Topics: Acetaminophen; Aminopyrine; Analgesics; Animals; Aspirin; Chlorpromazine; Codeine; Diazepam; Diphenhydramine; Electric Stimulation; Haloperidol; Hot Temperature; Hydroxyzine; Imipramine; Isocarboxazid; Male; Meprobamate; Mice; Morphine; Perphenazine; Phenobarbital; Phenothiazines; Promazine; Promethazine; Reserpine; Tetrabenazine; Thiopental; Time Factors; Tranquilizing Agents | 1968 |
Potentiation of morphine analgesia by cocaine in mice.
Topics: Amphetamine; Analgesia; Animals; Cocaine; Dibucaine; Drug Synergism; Female; Imipramine; Lidocaine; Male; Mice; Morphine; Norepinephrine; Phentolamine; Procaine; Rats; Reserpine | 1968 |
The influence of imipramine on the "abstinence syndrome" to morphine in mice.
Topics: Animals; Humans; Imipramine; Male; Mice; Morphine; Nalorphine; Postural Balance; Substance Withdrawal Syndrome | 1968 |
The thyroid and the reactivity of the organism to drugs.
Topics: Amobarbital; Animals; Chlordiazepoxide; Drug Hypersensitivity; Hyperthyroidism; Imipramine; Male; Mice; Morphine; Reserpine; Thyroid Gland; Thyroid Hormones | 1968 |
Inhibition of phospholipid-facilitated calcium transport by central nervous system-acting drugs.
Topics: Amphetamine; Analgesics; Animals; Biological Transport; Brain; Calcium; Calcium Isotopes; Carbon Isotopes; Cell Membrane; Chlordiazepoxide; Chlorpromazine; Guinea Pigs; Hydrogen-Ion Concentration; Imipramine; Metals; Morphine; Nalorphine; Narcotics; Pentobarbital; Phospholipids | 1969 |
Thin-layer chromatographic detection of barbiturates, narcotics, and amphetamines in urine of patients receiving psychotropic drugs.
Topics: Amphetamine; Barbiturates; Chlorpromazine; Chromatography, Thin Layer; Cocaine; Codeine; Humans; Imipramine; Ion Exchange Resins; Meperidine; Methadone; Morphine; Narcotics; Quinine; Thioridazine; Trifluoperazine | 1969 |
[Modification of central mechanisms of action by anticholinergics].
Topics: Aggression; Amphetamine; Animals; Apomorphine; Atropine; Biperiden; Bridged-Ring Compounds; Central Nervous System; Chlorpromazine; Depression, Chemical; Drug Synergism; Esters; Female; Hexobarbital; Humans; Imipramine; Male; Mice; Morphine; Nicotine; Parasympatholytics; Pentylenetetrazole; Perphenazine; Rats; Stimulation, Chemical; Strychnine; Tremorine | 1969 |
Changes in the metabolism of 3,4-dihydroxyphenylethylamine (dopamine) in the striatum of the mouse induced by drugs.
Topics: Anesthetics; Animals; Behavior, Animal; Brain; Dopamine; Drug Antagonism; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Methylphenidate; Methyltyrosines; Mice; Mixed Function Oxygenases; Monoamine Oxidase; Morphine; Parasympatholytics; Parasympathomimetics; Pargyline; Phencyclidine; Phenylacetates; Pilocarpine; Probenecid; Reserpine; Tolazoline; Tranquilizing Agents; Tyrosine; Zoxazolamine | 1966 |
Inhibition of evoked potentials by caudate stimulation and its antagonism by centrally acting drugs.
Topics: Amphetamine; Amygdala; Animals; Bemegride; Caffeine; Cats; Caudate Nucleus; Cerebral Cortex; Chlorpromazine; Electric Stimulation; Electrophysiology; Evoked Potentials; Forelimb; Hippocampus; Hypothalamus; Imipramine; Medulla Oblongata; Mephenesin; Morphine; Neurons; Pentobarbital; Pentylenetetrazole; Picrotoxin; Reticular Formation; Strychnine; Thalamus | 1967 |
New, simple method for the informative investigation of sedatives.
Topics: Amphetamine; Animals; Chlordiazepoxide; Chlorpromazine; Diazepam; Escape Reaction; Glutethimide; Haloperidol; Hypnotics and Sedatives; Imipramine; Male; Meprobamate; Methadone; Methods; Mice; Morphine; Nialamide; Pentobarbital; Phenobarbital; Reserpine; Tubocurarine; Urethane | 1967 |
Sensitivity in vivo of central alpha 2- and opiate receptors after chronic treatment with various antidepressants.
Topics: Animals; Antidepressive Agents; Brompheniramine; Chlorpromazine; Clomipramine; Clonidine; Desipramine; Evoked Potentials; Imipramine; Iprindole; Locus Coeruleus; Male; Mianserin; Morphine; Neural Inhibition; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Opioid; Zimeldine | 1982 |
Behavioural effects of hashish in mice in comparison with other psychoactive drugs.
Topics: Aggression; Amphetamine; Animals; Behavior, Animal; Cannabis; Chlorpromazine; Diazepam; Humans; Imipramine; Male; Mice; Mice, Inbred Strains; Morphine; Motor Activity; Psychotropic Drugs; Social Behavior | 1982 |
[Comparison of the effects of several psychotropic drugs by gross behavioral observation on rhesus monkeys].
Topics: Amphetamines; Animals; Barbital; Behavior, Animal; Chlorpromazine; Cocaine; Diazepam; Female; Imipramine; Lysergic Acid Diethylamide; Macaca mulatta; Male; Morphine; Psychotropic Drugs | 1981 |
Implication of endogenous opioid system in the learned helplessness model of depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Avoidance Learning; Depression; Electroshock; Endorphins; Enkephalins; Helplessness, Learned; Hydroxamic Acids; Imipramine; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neprilysin; Phenylalanine; Protease Inhibitors; Rats; Rats, Wistar | 1995 |
Effects of morphine, naloxone, buprenorphine, butorphanol, haloperidol and imipramine on morphine withdrawal signs in cynomolgus monkeys.
Topics: Animals; Behavior, Animal; Buprenorphine; Butorphanol; Haloperidol; Imipramine; Macaca fascicularis; Male; Morphine; Morphine Dependence; Naloxone; Psychotropic Drugs; Substance Withdrawal Syndrome | 1994 |
Effects of psychotropic drugs on impairment of acquisition of shuttle avoidance produced by pretreatment with pairs of tone signal and shock in mice.
Topics: Animals; Avoidance Learning; Caffeine; Chlorpromazine; Diazepam; Electroshock; Imipramine; Male; Mice; Morphine; Nicotine; Psychotropic Drugs; Signal Detection, Psychological | 1994 |
Fentanyl inhibits the uptake of [3H]noradrenaline in cultured neuronal cells.
Topics: Adrenal Gland Neoplasms; Animals; Dose-Response Relationship, Drug; Fentanyl; Humans; Imipramine; Morphine; Naloxone; Neuroblastoma; Neurons; Norepinephrine; Pheochromocytoma; Rats; Time Factors; Tumor Cells, Cultured | 1993 |
Interaction of opioids with antidepressant-induced antinociception.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Clomipramine; Drug Combinations; Female; Imipramine; Male; Maprotiline; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pain Measurement; Random Allocation; Selective Serotonin Reuptake Inhibitors; Zimeldine | 1995 |
Chronic antidepressant treatments increase cytochrome b mRNA levels in mouse cerebral cortex.
Topics: Animals; Antidepressive Agents; Cerebral Cortex; Cytochrome b Group; Drug Administration Schedule; Electroshock; Gene Expression Regulation; Haloperidol; Imipramine; Injections, Intraperitoneal; Male; Mice; Morphine; RNA, Messenger | 1997 |
GABA(B) receptor mechanism and imipramine-induced antinociception in ligated and non-ligated mice.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Tricyclic; Baclofen; GABA Agonists; GABA Antagonists; Imipramine; Ligation; Male; Mice; Morphine; Organophosphorus Compounds; Pain Measurement; Receptors, GABA-B; Sciatic Nerve | 2000 |
Effect of imipramine on tolerance to morphine antinociception in the formalin test.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Disinfectants; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Formaldehyde; Imipramine; Injections, Intraperitoneal; Male; Mice; Morphine; Naloxone; Pain | 2000 |
Effect of alpha-adrenoceptor agents on imipramine-induced antinociception in nerve-ligated mice.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Imipramine; Ligation; Male; Mice; Morphine; Pain Measurement; Sciatic Nerve; Sciatic Neuropathy | 2001 |
Evaluation of the marmoset as a model species for drug glucuronidation.
Topics: Animals; Callithrix; Female; Glucuronates; Imipramine; Inactivation, Metabolic; Kidney; Male; Microsomes, Liver; Models, Animal; Morphine; Propofol; Rats; Rats, Sprague-Dawley; Species Specificity | 2001 |
Experimental conditions for the continuous subcutaneous infusion of four central analgesics in rats.
Topics: Acetates; Amines; Analgesics; Anesthetics, Dissociative; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Chronic Disease; Convulsants; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Hypothermia; Imipramine; Infusion Pumps, Implantable; Ketamine; Male; Morphine; Pain; Pain Measurement; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Solubility; Tetrabenazine | 2002 |
Effect of imipramine on the expression and acquisition of morphine-induced conditioned place preference in mice.
Topics: Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Imipramine; Male; Mice; Morphine; Motor Activity | 2002 |
Large-amplitude 5-HT1A receptor activation: a new mechanism of profound, central analgesia.
Topics: Acetates; Adrenergic Uptake Inhibitors; Amines; Aminopyridines; Analgesia; Analgesics; Animals; Cells, Cultured; CHO Cells; Cricetinae; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Synergism; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hyperalgesia; Imipramine; Ketamine; Male; Morphine; Pain; Pain Measurement; Pain Threshold; Piperidines; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Time Factors; Transfection | 2002 |
Effects of imipramine on the expression and development of morphine dependence in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Clonidine; Dose-Response Relationship, Drug; Imipramine; Injections, Subcutaneous; Male; Mice; Morphine; Morphine Dependence; Motor Activity; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Yohimbine | 2003 |
Cause of death in narcotic intoxication in recent years.
Topics: Cause of Death; Chlorprothixene; Heart Diseases; Humans; Imipramine; Kidney Diseases; Lung Diseases; Meperidine; Morphine; Narcotics; Shock | 1963 |
Effects of morphine and Tofranil on the incorporation of phosphate (32P) into phospolipids of rat brain slices.
Topics: Animals; Brain; Imipramine; Morphine; Phosphates; Phospholipids; Rats | 1963 |
HYPERMOTILITY EVOKED BY LESIONS OF THE SEPTUM AND ANTERIOR HYPOTHALAMUS.
Topics: Aminopyrine; Amygdala; Atropine; Body Temperature; Caudate Nucleus; Cerebral Ventricles; Chlorpromazine; Electrocoagulation; Ephedrine; Hexobarbital; Hippocampus; Hypothalamus; Hypothalamus, Anterior; Imipramine; Iproniazid; Metabolism; Morphine; Movement Disorders; Physostigmine; Rats; Research; Reserpine; Scopolamine | 1963 |
A SIMPLE SCREENING PROCEDURE FOR IMIPRAMINE-LIKE ANTIDEPRESSANT AGENTS.
Topics: 5-Hydroxytryptophan; Amitriptyline; Amphetamine; Amphetamines; Antidepressive Agents; Atropine; Bemegride; Chlorpromazine; Diethylpropion; Dihydroxyphenylalanine; Epinephrine; Hypothermia; Hypothermia, Induced; Imipramine; Indoles; Iproniazid; Lysergic Acid Diethylamide; Mice; Morphine; Nialamide; Pentylenetetrazole; Pharmacology; Phenelzine; Promethazine; Research; Reserpine | 1963 |
Drug administration to cerebral cortex of freely moving dogs.
Topics: Amobarbital; Animals; Cerebral Cortex; Dogs; Imipramine; Morphine | 1962 |
Cocaine and other indirect-acting monoamine agonists differentially attenuate a naltrexone discriminative stimulus in morphine-treated rhesus monkeys.
Topics: Amphetamine; Animals; Biogenic Monoamines; Cocaine; Discrimination Learning; Disease Models, Animal; Dopamine Agents; Dopamine Uptake Inhibitors; Drug Interactions; Imipramine; Macaca mulatta; Morphine; Morphine Dependence; Naltrexone; Narcotics; Substance Withdrawal Syndrome | 2004 |
Interactions of acute morphine with chronic imipramine and fluvoxamine treatment on the antinociceptive effect in arthritic rats.
Topics: Analgesics; Animals; Arthritis, Experimental; Drug Interactions; Fluvoxamine; Imipramine; Male; Morphine; Pain Measurement; Rats; Rats, Wistar | 2003 |
Eye-wiping test: a sensitive animal model for acute trigeminal pain studies.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Behavior, Animal; Cornea; Data Interpretation, Statistical; Disease Models, Animal; Eye; Imipramine; Irritants; Male; Morphine; Pain; Pain Measurement; Rats; Rats, Wistar; Reaction Time; Salicylates; Sodium Chloride; Trigeminal Neuralgia | 2005 |
Suppressive effect of imipramine on vincristine-induced mechanical allodynia in mice.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Tricyclic; Antineoplastic Agents, Phytogenic; Hyperalgesia; Imipramine; Male; Mice; Mice, Inbred ICR; Morphine; Pain Measurement; Sciatic Neuropathy; Vincristine | 2009 |
Interaction between behavioral despair and addictive behaviors in rats.
Topics: Animals; Behavior, Addictive; Choice Behavior; Conditioning, Classical; Depression; Disease Models, Animal; Drug Interactions; Food; Imipramine; Male; Morphine; Motor Activity; Rats; Rats, Sprague-Dawley; Swimming; Time Factors | 2011 |
Hepatic microsomal UDP-glucuronosyltransferase (UGT) activities in the microminipig.
Topics: Adult; Aged; Animals; Chromatography, Liquid; Dogs; Estradiol; Female; Glucuronides; Glucuronosyltransferase; Humans; Imipramine; Macaca fascicularis; Male; Mice, Inbred ICR; Microsomes, Liver; Middle Aged; Morphine; Propofol; Rats, Sprague-Dawley; Serotonin; Species Specificity; Swine; Swine, Miniature; Tandem Mass Spectrometry; Young Adult; Zidovudine | 2014 |
Effects of Adjuvant Analgesics on Cerebral Ischemia-Induced Mechanical Allodynia.
Topics: Amines; Analgesics; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Brain Ischemia; Carbamazepine; Chemotherapy, Adjuvant; Cyclohexanecarboxylic Acids; Cyclopropanes; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Imipramine; Indomethacin; Male; Mexiletine; Mice; Milnacipran; Morphine; Neuralgia; Paroxetine; Selective Serotonin Reuptake Inhibitors | 2016 |
Irinotecan Alters the Disposition of Morphine Via Inhibition of Organic Cation Transporter 1 (OCT1) and 2 (OCT2).
Topics: Amitriptyline; Animals; Drug Interactions; Fluoxetine; HEK293 Cells; Humans; Imipramine; Irinotecan; Mice, Inbred C57BL; Morphine; Narcotics; Ondansetron; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Tissue Distribution; Verapamil | 2018 |