imipramine and morphine

imipramine has been researched along with morphine in 131 studies

Research

Studies (131)

TimeframeStudies, this research(%)All Research%
pre-199082 (62.60)18.7374
1990's11 (8.40)18.2507
2000's25 (19.08)29.6817
2010's13 (9.92)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Anderson, VB; Geyer, HM; Kruse, H; Ong, HH; Profitt, JA; Spaulding, TC; Wilker, JC1
Strassburg, CP; Tukey, RH1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Chang, TK; Ensom, MH; Kiang, TK1
Nagashima, R; Nishikawa, T; Tobita, M1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Fitzsimons, JT; Loker, JE; Smith, PA; Walker, RJ1
Bissada, NK; Finkbeiner, AE; Welch, LT1
Bates, A; Shuster, L; Yu, G1
Kelder, D; Ross, SB1
Bhattacharya, SK1
Pickens, R; Thompson, T1
Poignant, JC; Rismondo, N1
Celsen, B; Huppertz, A; Kuschinsky, K1
Kunihara, M; Nakano, M; Ohyama, M1
Ambrogi, F; Cassano, GB; Marazziti, D; Rotondo, A1
Alvarez, L; Asher, K; Bergman, SA; Thut, PD; Wynn, RL1
Gastmeier, K; Hass, M; Kuteifan, K; Schott, H1
Kuschinsky, K; Wenzel, J1
Berman, EF; Fujimoto, JM; Schaus, P1
Reny-Palasse, V; Rips, R1
Abbiati, G; Ibba, M; Schiavi, S; Testa, R1
Besson, JM; Butler, SH; Godefroy, F; Weil-Fugazza, J1
Bickel, MH; Di Francesco, C1
Hancock, S; Picker, M; Poling, A; Wallace, S1
Dews, PB; Lehr, E; Morse, WH1
Bell, S; Jhamandas, K; Sutak, M1
Schuster, CR; Wilson, MC1
Goldberg, SR; Hoffmeister, F1
Colhoun, E; Dubas, T; Lundy, P; Parker, JM1
Carroll, BJ; Sharp, PT1
Ahtee, L; Kääriäinen, I1
Greengard, P; Quinn, GP; Reid, MB1
Hartmann, E1
Kaniike, K; Kurogochi, Y1
Cater, BR; Chapman, D; Hawes, SM; Saville, J1
Mennear, JH; Rudzik, AD1
Dhalla, NS1
Gigon, PL; Gillette, JR; Gram, TE1
Mattila, MJ; Saarnivaara, L2
Saarnivaara, L1
Oldendorf, WH1
Gillette, JR; Hamrick, M; Stripp, B; Zampaglione, N1
Dubileĭ, PV; Urazaeva, ZV1
Kowa, Y; Nakama, M; Ochiai, T1
Kocher, R; Rohrer, G1
Männistö, PT; Saarnivaara, L1
Kaneto, H; Koida, M; Tsuchie, F1
Mann, WA; Ridley, PT1
McMillan, DE1
Gershon, S; Sanghvi, I1
Zakusov, VV1
Abe, A; Fujimura, H; Go, K; Hayashi, M; Tsurumi, K1
Knoll, J; Zsilla, G1
Ciofalo, FR1
Baden, MM; Valanju, NN; Valanju, SN; Verma, SK1
Domino, EF; Wilson, AE1
Delini-Stula, A1
Burov, IuV; Kurochkin, IG2
Bhalla, TN; Bhargava, KP; Kohli, RP; Sinha, JN1
Drew, WG; Fink, M; White, RP1
Kleinrok, Z; Langwiński, R; Ozimek, H1
Kreppel, E1
Bauer, BG; Brodie, DA; Lotti, VJ1
Imamura, H; Maruyama, Y; Nakanishi, M1
Eidelberg, E; Schwartz, AS1
Burov, IuV1
Senault, B1
Katz, MH; Krop, S; Yen, HC1
Kiplinger, GF1
Laplace, JP; Ruckebusch, Y1
Ibrahim, I; Sulman, FG; Weller, CP1
Nott, MW1
Banaru, A; Chiosa, L; Dumitrescu, S1
Winter, D1
Mulé, SJ1
Blumberg, AG; Heaton, AM1
Haas, H; Jantos, W1
Sharman, DF1
Collins, RJ; Simonton, VR1
Pálosi, E; Szporny, L1
Scuvée-Moreau, JJ; Svensson, TH1
Frischknecht, HR; Sieber, B; Waser, PG1
Kato, S; Yanagita, T1
Gibert-Rahola, J; Maldonado, R; Mico, JA; Roques, BP; Tejedor-Real, P1
Fukase, H; Fukuzaki, K; Koja, T; Lukas, SE; Nagata, R1
Kuribara, H1
Atcheson, R; Lambert, DG; Rowbotham, DJ1
Mendez, M; Miranda, HF; Pinardi, G; Sierralta, F1
Huang, NY; Layer, RT; Skolnick, P; Strakhova, M1
Sahebgharani, M; Valizadeh, S; Zarrindast, M1
Sahebgharani, M; Shaverdian, S; Zarrindast, MR1
Sahebgharani, M; Zarrindast, M1
Burchell, B; Riley, RJ; Soars, MG1
Bruins Slot, LA; Colpaert, FC; Koek, W; Ribet, JP; Tarayre, JP1
Adl, M; Bahreini, T; Zarrindast, MR1
Assié, MB; Bardin, L; Carilla-Durand, E; Colpaert, FC; Cosi, C; Koek, W; Pauwels, PJ; Tarayre, JP; Vacher, B; Wiesenfeld-Hallin, Z; Xu, XJ1
Torkaman-Boutorabi, A; Zarrindast, MR1
JACOBSEN, P1
BROSSARD, M; QUASTEL, JH1
ENDROECZI, E; KORANYI, L; LISSAK, K1
ASKEW, BM1
KOBAYASHI, T1
France, CP; McMahon, LR; Sell, SL1
Gibert-Rahola, J; Gutiérrez, M; Micó, JA; Ortega-Alvaro, A1
Farazifard, R; Javan, M; Safarpour, F; Sheibani, V1
Fukazawa, Y; Kiguchi, N; Kishioka, S; Kobayashi, Y; Maeda, T; Ozaki, M; Saika, F1
Cao, J; Mao, RR; Tian, M; Wang, LP; Xu, L; Zhou, QX1
Ando, A; Higashi, E; Iwano, S; Miyamoto, Y; Murayama, N; Yamazaki, H1
Harada, S; Matsuura, W; Tokuyama, S1
Guo, D; Guo, J; Huang, S; Li, Q; Polli, JE; Shu, Y; Xiong, Z; Ye, Z; Zhang, W; Zhou, H; Zhu, P1

Reviews

6 review(s) available for imipramine and morphine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Uropharmacology: X. Central nervous system stimulants and depressants.
    Urology, 1979, Volume: 13, Issue:4

    Topics: Amphetamines; Anesthetics; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Baclofen; Benzodiazepines; Central Nervous System Agents; Chloral Hydrate; Humans; Imipramine; Levodopa; Meperidine; Meprobamate; Morphine; Nortriptyline; Paraldehyde; Phenothiazines; Phenytoin; Picrotoxin; Reserpine; Strychnine; Urinary Tract

1979
An experimental analysis of behavioral factors in drug dependence.
    Federation proceedings, 1975, Volume: 34, Issue:9

    Topics: Administration, Oral; Alcoholism; Amphetamine; Animals; Behavior, Animal; Cannabis; Chlorpromazine; Cocaine; Dextroamphetamine; Drinking Behavior; Dronabinol; Ethanol; Humans; Imipramine; Injections, Intravenous; Macaca mulatta; Morphine; Pentobarbital; Reinforcement Schedule; Secobarbital; Social Environment; Substance-Related Disorders; Time Factors

1975
Pharmacological studies of sleep and dreaming: chemical and clinical relationships.
    Biological psychiatry, 1969, Volume: 1, Issue:3

    Topics: Amitriptyline; Amphetamine; Antidepressive Agents; Atropine; Chloralose; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Diazepam; Diphenhydramine; Dreams; Glutethimide; Humans; Hypnotics and Sedatives; Imipramine; Lysergic Acid Diethylamide; Meprobamate; Methaqualone; Morphine; Nialamide; Pentobarbital; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tranylcypromine; Triiodothyronine; Tryptophan

1969

Trials

1 trial(s) available for imipramine and morphine

ArticleYear
[Treatment of severe chronic pains with a combination of thymoleptics and neuroleptics (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1974, Dec-31, Volume: 63, Issue:52

    Topics: Adult; Antidepressive Agents; Atropine; Chlorpromazine; Clinical Trials as Topic; Clomipramine; Drug Combinations; Female; Haloperidol; Humans; Imipramine; Male; Methotrimeprazine; Middle Aged; Morphine; Neoplasms; Pain; Papaverine; Tranquilizing Agents

1974

Other Studies

124 other study(ies) available for imipramine and morphine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Tricyclics with analgesic and antidepressant activity. 1. [[(Alkylamino)ethyl]thio]dibenz[b,f]oxepins and 10,11-dihydro derivatives.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:5

    Topics: Amphetamine; Analgesics; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chemical Phenomena; Chemistry; Dibenzoxepins; Mice

1980
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
5-hydroxytryptamine as a possible inhibitory neurotransmitter in the central nervous system of the leech, Haemopis sanguisuga.
    Comparative biochemistry and physiology. C: Comparative pharmacology, 1975, Oct-01, Volume: 52, Issue:1

    Topics: Central Nervous System; Ganglia; Imipramine; Leeches; Microscopy, Electron; Microscopy, Fluorescence; Morphine; Neurons; Serotonin

1975
Sensitization to cocaine stimulation in mice.
    Psychopharmacology, 1977, Apr-29, Volume: 52, Issue:2

    Topics: Animals; Brain Chemistry; Cocaine; Cycloheximide; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Female; Imipramine; Male; Mice; Mice, Inbred A; Mice, Inbred BALB C; Mice, Inbred C57BL; Morphine; Motor Activity; Norepinephrine; Reserpine; Species Specificity; Stimulation, Chemical; Time Factors

1977
Release of 3H-noradrenaline from the rat vas deferens under various in vitro conditions.
    Acta physiologica Scandinavica, 1979, Volume: 105, Issue:3

    Topics: Aminobenzoates; Amphetamine; Anesthetics, Local; Animals; Calcium; Choline; Desipramine; Dose-Response Relationship, Drug; Imipramine; Male; Morphine; Norepinephrine; Potassium; Rats; Reserpine; Sodium; Vas Deferens; Veratridine

1979
Imipramine-induced potentiation of morphine analgesia in the rat: role of brain monoamines.
    The Indian journal of medical research, 1978, Volume: 68

    Topics: Analgesia; Animals; Biogenic Amines; Drug Synergism; Female; Imipramine; Male; Morphine; Rats

1978
[Influence of the administration of psychopharmacological compounds on the take up time of an alimentary material in the hamster and a study of the associated behaviour (author's transl)].
    Psychopharmacologia, 1975, Jul-23, Volume: 43, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Clonidine; Cricetinae; Dextroamphetamine; Diazepam; Feeding Behavior; Fenfluramine; Humans; Imipramine; Male; Meprobamate; Mesocricetus; Morphine; Motor Activity; Phenobarbital; Piribedil; Psychotropic Drugs; Stereotyped Behavior; Sulpiride; Time Factors

1975
Studies on dopamine kinetics in rat brain tissue under the influence of morphine.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Animals; Apomorphine; Corpus Striatum; Dextroamphetamine; Dopamine; Humans; Imipramine; In Vitro Techniques; Kinetics; Morphine; Morphine Dependence; Naloxone; Potassium; Rats; Sensory Receptor Cells; Stereotyped Behavior

1975
Central monoaminergic mechanisms in mice and analgesic activity of spiradoline mesylate, a selective kappa-opioid receptor agonist.
    European journal of pharmacology, 1992, Apr-22, Volume: 214, Issue:2-3

    Topics: Analgesics; Animals; Brain; Clomipramine; Desipramine; Fenclonine; Imipramine; Male; Mice; Mice, Inbred ICR; Morphine; Norepinephrine; Phenoxybenzamine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Reserpine; Serotonin

1992
Analgesia by nefopam: does it act through serotonin?
    Drugs under experimental and clinical research, 1991, Volume: 17, Issue:5

    Topics: Analgesia; Blood Platelets; Desipramine; Dose-Response Relationship, Drug; Humans; Imipramine; Morphine; Nefopam; Orphenadrine; Serotonin Antagonists

1991
Imipramine-fentanyl antinociception in a rabbit tooth pulp model.
    Life sciences, 1991, Volume: 49, Issue:18

    Topics: Analgesics; Animals; Carbon Dioxide; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Electric Stimulation; Female; Fentanyl; Imipramine; Injections, Intravenous; Kinetics; Male; Morphine; Naloxone; Nociceptors; Rabbits; Respiration

1991
[Pain therapy for urologic cancer patients at the Potsdam district hospital--initial results].
    Zeitschrift fur Urologie und Nephrologie, 1990, Volume: 83, Issue:10

    Topics: Aged; Amitriptyline; Analgesics; Analgesics, Opioid; Aspirin; Carbamazepine; Codeine; Dipyrone; Drug Therapy, Combination; Haloperidol; Humans; Imipramine; Indomethacin; Meperidine; Morphine; Pain; Pain Measurement; Prospective Studies; Urologic Neoplasms

1990
Interactions between imipramine and morphine on motility in rats: possible relation to antidepressant effects?
    Pharmacopsychiatry, 1990, Volume: 23, Issue:6

    Topics: Animals; Behavior, Animal; Depressive Disorder; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Imipramine; Male; Morphine; Motor Activity; Rats; Rats, Inbred Strains; Stereotyped Behavior

1990
Comparison of the inhibition of biliary excretion produced by certain inducing agents including 2,3,7,8-tetrachlorodibenzo-p-dioxin.
    Journal of toxicology and environmental health, 1986, Volume: 17, Issue:4

    Topics: Animals; Bile; Carbon Radioisotopes; Chlordecone; Dioxins; Drug Interactions; Imipramine; Injections, Intraperitoneal; Insecticides; Male; Mirex; Morphine; Ouabain; Pentobarbital; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred Strains; Tritium; Urethane

1986
Potentiation by TRH of the effect of imipramine on the forced-swimming test.
    British journal of pharmacology, 1985, Volume: 85, Issue:2

    Topics: Animals; Drug Synergism; Drug Tolerance; Imipramine; Male; Mice; Morphine; Naloxone; Phenoxybenzamine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha; Receptors, Opioid; Swimming; Thyrotropin-Releasing Hormone; Yohimbine

1985
Effects of oral administration of nortriptyline, imipramine and citalopram on morphine hot-plate and tail-immersion analgesia in rats.
    Bollettino chimico farmaceutico, 1987, Volume: 126, Issue:2

    Topics: Analgesia; Animals; Antidepressive Agents; Citalopram; Drug Interactions; Imipramine; Male; Morphine; Nortriptyline; Propylamines; Rats; Reaction Time

1987
Do acute or chronic tricyclic antidepressants modify morphine antinociception in arthritic rats?
    Pain, 1986, Volume: 25, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Arthritis; Arthritis, Experimental; Drug Synergism; Drug Therapy, Combination; Imipramine; Male; Morphine; Nociceptors; Pain; Rats; Rats, Inbred Strains; Sensory Thresholds; Vocalization, Animal

1986
Uptake in vitro of lipophilic model compounds into adipose tissue preparations and lipids.
    Biochemical pharmacology, 1985, Oct-15, Volume: 34, Issue:20

    Topics: Adipose Tissue; Animals; Carbon Radioisotopes; Chlorpromazine; Glutethimide; Half-Life; Imipramine; In Vitro Techniques; Kinetics; Male; Morphine; Polychlorinated Biphenyls; Rats; Scintillation Counting; Thiopental

1985
Discriminative stimulus properties of valproic acid in the pigeon.
    Psychopharmacology, 1985, Volume: 87, Issue:4

    Topics: Animals; Anticonvulsants; Columbidae; Dextroamphetamine; Discrimination Learning; Generalization, Psychological; Imipramine; Morphine; Pentylenetetrazole; Valproic Acid

1985
Effects of drugs on schedule-controlled running of mice in a circular runway.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:1A

    Topics: Amphetamine; Animals; Chlordiazepoxide; Chlorpromazine; Clozapine; Female; Food Deprivation; Imipramine; Mice; Morphine; Motor Activity; Pentobarbital; Reinforcement Schedule

1985
Modification of precipitated morphine withdrawal syndrome by drugs affecting cholinergic mechanisms.
    European journal of pharmacology, 1973, Volume: 24, Issue:3

    Topics: Animals; Atropine; Autonomic Nervous System; Diphenhydramine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Imipramine; Mecamylamine; Morphine; Morphine Dependence; Naloxone; Neurotransmitter Agents; Physostigmine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Substance Withdrawal Syndrome; Synaptic Transmission; Tolazoline

1973
The effects of stimulants and depressants on cocaine self-administration behavior in the rhesus monkey.
    Psychopharmacologia, 1973, Aug-03, Volume: 31, Issue:4

    Topics: Animals; Cocaine; Exploratory Behavior; Grooming; Haplorhini; Imipramine; Locomotion; Macaca; Male; Morphine; Motor Activity; Pentobarbital; Phenmetrazine; Self Medication; Trifluoperazine

1973
A comparison of chlorpromazine, imipramine, morphine and d-amphetamine self-administration in cocaine-dependent rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 187, Issue:1

    Topics: Animals; Behavior, Animal; Chlorpromazine; Cocaine; Dextroamphetamine; Dose-Response Relationship, Drug; Haplorhini; Humans; Imipramine; Macaca; Morphine; Self Stimulation; Substance-Related Disorders

1973
Investigation of mechanisms involved in toxic effects of narcotic analgesics.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1972, Volume: 5, Issue:4

    Topics: Analgesics; Animals; Brain; Brain Chemistry; Catecholamines; Dextropropoxyphene; Drug Interactions; Female; Fenclonine; Heroin; Imipramine; Lethal Dose 50; Morphine; Naloxone; Narcotics; Norepinephrine; Pargyline; Rats; Reserpine; Tranylcypromine; Tyrosine

1972
Monoamine mediation of the morphine-induced activation of mice.
    British journal of pharmacology, 1972, Volume: 46, Issue:1

    Topics: 5-Hydroxytryptophan; Aniline Compounds; Animals; Atropine; Chlorpromazine; Cinnamates; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Drug Synergism; Fenclonine; Haloperidol; Imipramine; Male; Methyltyrosines; Methysergide; Mice; Monoamine Oxidase Inhibitors; Morphine; Motor Activity; Nalorphine; Pargyline; Phenoxybenzamine; Phentolamine; Reserpine

1972
5-hydroxytryptamine in platelets and brain of rabbits treated chronically with imipramine, morphine or methadone.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 277, Issue:4

    Topics: Animals; Blood Platelets; Brain Chemistry; Hydroxyindoleacetic Acid; Imipramine; Male; Methadone; Morphine; Rabbits; Serotonin; Time Factors

1973
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
    Molecular pharmacology, 1966, Volume: 2, Issue:4

    Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine

1966
[Effect of psychotropic drugs on the K + -dependent phosphatase activity in guinea pig brain microsomes].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Chlordiazepoxide; Chlorpromazine; Desipramine; Diazepam; Guinea Pigs; Histamine; Hydroxyzine; Imipramine; Meprobamate; Microsomes; Morphine; Nialamide; Phenelzine; Phenobarbital; Phenoxybenzamine; Phosphoric Monoester Hydrolases; Pilocarpine; Potassium; Procaine; Reserpine; Tranquilizing Agents

1972
Lipid phase transitions and drug interactions.
    Biochimica et biophysica acta, 1974, Aug-21, Volume: 363, Issue:1

    Topics: Amitriptyline; Binding Sites; Calorimetry; Desipramine; Electron Spin Resonance Spectroscopy; Imipramine; Kinetics; Magnetic Resonance Spectroscopy; Membranes, Artificial; Models, Biological; Molecular Conformation; Morphinans; Morphine; Nortriptyline; Palmitic Acids; Phosphatidylcholines; Structure-Activity Relationship; Temperature; Thermodynamics

1974
Potentiation of the anticonvulsant action of acetazolamide.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:12

    Topics: Acetazolamide; Amphetamine; Animals; Anticonvulsants; Caffeine; Cocaine; Desipramine; Drug Synergism; Electric Stimulation; Electroshock; Ephedrine; Histamine H1 Antagonists; Imipramine; Isoproterenol; Male; Metaraminol; Mice; Morphine; Phenethylamines; Quaternary Ammonium Compounds; Seizures; Stress, Physiological; Tranylcypromine; Tyramine

1966
Mechanisms of sympathomimetic effects of dichloroisoproterenol: comparison with tyramine, nicotine and norepinephrine.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 157, Issue:1

    Topics: Animals; Atropine; Cocaine; Diaphragm; Drug Antagonism; Ganglionic Blockers; Guanidines; Heart; Heart Atria; Hexamethonium Compounds; Imipramine; In Vitro Techniques; Iproniazid; Isoproterenol; Morphine; Nicotine; Norepinephrine; Pentolinium Tartrate; Phenoxybenzamine; Propranolol; Rats; Sympatholytics; Tranylcypromine; Tyramine

1967
Effect of drug substrates on the reduction of hepatic microsomal cytochrome P-450 by NADPH.
    Biochemical and biophysical research communications, 1968, May-23, Volume: 31, Issue:4

    Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; Kinetics; Liver; Male; Microsomes; Morphine; NADP; Niacinamide; Oxidation-Reduction; Pigments, Biological; Proadifen; Rats; Sex Factors; Spectrophotometry; Transferases

1968
Modification by antihistaminic drugs of the morphine analgesia in rabbits.
    Annales medicinae experimentalis et biologiae Fenniae, 1968, Volume: 46, Issue:1

    Topics: Analgesia; Animals; Drug Synergism; Histamine H1 Antagonists; Imipramine; Morphine; Rabbits; Reserpine

1968
Influence of some drugs on the accumulation of morphine in rabbit red cells in vitro.
    Annales medicinae experimentalis et biologiae Fenniae, 1969, Volume: 47, Issue:2

    Topics: Analgesia; Animals; Cyproheptadine; Diphenhydramine; Dopamine; Drug Synergism; Erythrocytes; Hemolysis; Histamine H1 Antagonists; Imipramine; In Vitro Techniques; Indomethacin; Isotonic Solutions; Male; Morphine; Norepinephrine; Phenothiazines; Pyrrolidines; Rabbits; Serotonin

1969
Brain uptake of metabolites and drugs following carotid arterial injections.
    Transactions of the American Neurological Association, 1971, Volume: 96

    Topics: Acetates; Amino Acids; Animals; Antipyrine; Ascorbic Acid; Aspirin; Barbiturates; Blood-Brain Barrier; Brain; Caffeine; Chloroquine; Cyanides; Ethanol; Imipramine; Lactates; Mescaline; Morphine; Neurotransmitter Agents; Nicotine; Penicillin G; Pharmaceutical Preparations; Phenytoin; Procaine; Pyruvates; Rats

1971
An approach measurement of the stoichiometric relationship between hepatic microsomal drug metabolism and the oxidation of reduced nicotinamide adenine dinucleotide phosphate.
    Molecular pharmacology, 1972, Volume: 8, Issue:2

    Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Benzyl Compounds; Chlorine; Dealkylation; Ethylamines; Hexobarbital; Imipramine; Male; Methylamines; Microsomes, Liver; Morphine; NADP; Oxidation-Reduction; Pharmaceutical Preparations; Rats

1972
[Role of the lungs in the inactivation of serotonin].
    Biulleten' eksperimental'noi biologii i meditsiny, 1974, Volume: 78, Issue:8

    Topics: Animals; Body Temperature; Cocaine; Cyanides; Imipramine; Iodoacetates; Lung; Lysergic Acid Diethylamide; Monoamine Oxidase Inhibitors; Morphine; Potassium; Rats; Serotonin; Time Factors

1974
Effects of psychotropic drugs on emotional behavior: exploratory behavior of naive rats in holed open field.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:6

    Topics: Animals; Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Defecation; Diazepam; Emotions; Exploratory Behavior; Hallucinogens; Haloperidol; Imipramine; Male; Meprobamate; Mescaline; Methamphetamine; Methods; Morphine; Motor Activity; Perphenazine; Rats; Time Factors; Tranquilizing Agents

1972
Effect of lithium on the analgesia caused by morphine and two antidepressants in mice.
    Pharmacology, 1972, Volume: 8, Issue:4

    Topics: Analgesia; Animals; Antidepressive Agents; Dibenzocycloheptenes; Imipramine; Lithium; Male; Mice; Morphine; Motor Activity; Postural Balance; Quinones; Time Factors

1972
[Tolerance and physical dependence producing liability of doxepin].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:6

    Topics: Amitriptyline; Animals; Body Weight; Diazepam; Dibenzoxepins; Drug Resistance; Humans; Imipramine; Male; Mice; Morphine; Motor Activity; Phenobarbital; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders

1972
Central antisecretory action of desmethylimipramine in the rat.
    The American journal of digestive diseases, 1973, Volume: 18, Issue:6

    Topics: Animals; Central Nervous System; Chlorpromazine; Desipramine; Gastric Juice; Gastric Mucosa; Imipramine; Injections, Intravenous; Male; Morphine; Rats; Stomach

1973
Drugs and punished responding. I. Rate-dependent effects under multiple schedules.
    Journal of the experimental analysis of behavior, 1973, Volume: 19, Issue:1

    Topics: Animals; Chlordiazepoxide; Chlorpromazine; Columbidae; Conditioning, Operant; Dextroamphetamine; Diazepam; Dronabinol; Feeding Behavior; Imipramine; Male; Meprobamate; Mescaline; Morphine; Oxazepam; Pentobarbital; Psychopharmacology; Punishment; Reinforcement Schedule; Tetrabenazine

1973
Rubidium and lithium: evaluation as antidepressant and anti-manic agents.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:1

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Drug Synergism; Imipramine; Lithium; Male; Mice; Morphine; Motor Activity; Photometry; Rubidium; Time Factors

1973
[The effect tranquilizers and antidepressants on the summation of impulses of different modalities].
    Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 75, Issue:4

    Topics: Animals; Auditory Perception; Central Nervous System; Chlordiazepoxide; Conditioning, Classical; Depression, Chemical; Diazepam; Imipramine; Morphine; Pain; Rats; Stimulation, Chemical; Thalamus; Visual Perception

1973
[Anti-inflammatory and analgesic effects of benzodiazepine derivatives].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzazepines; Capillary Permeability; Chlorpromazine; Drug Synergism; Edema; Female; Granuloma; Imipramine; Male; Mice; Morphine; Phenylbutazone; Pyrazoles; Pyrimidines; Rats

1973
Possible mechanism of the low tolerance capacity of azidomorphine and azidocodeine.
    Biochemical pharmacology, 1974, Feb-01, Volume: 23, Issue:3

    Topics: Animals; Azides; Codeine; Culture Media; Dealkylation; Drug Tolerance; Imipramine; Lethal Dose 50; Liver; Male; Morphinans; Morphine; Oxidoreductases, N-Demethylating; Rats; Rats, Inbred Strains; Time Factors

1974
Methadone inhibition of 3H-5-hydroxytryptamine uptake by synaptosomes.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 189, Issue:1

    Topics: Animals; Brain; Centrifugation, Density Gradient; Cold Temperature; Dinitrophenols; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Kinetics; Male; Methadone; Monoamine Oxidase Inhibitors; Morphine; Naloxone; Ouabain; Potassium Chloride; Rabbits; Serotonin; Serotonin Antagonists; Sucrose; Synaptosomes; Tritium

1974
Comparison of tricyclic antidepressants in rabbits: antinociception and potentiation of the noradrenaline pressor responses.
    Psychopharmacologia, 1974, Feb-27, Volume: 35, Issue:3

    Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Aorta; Blood Pressure; Chlorpromazine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Doxepin; Drug Synergism; Imipramine; In Vitro Techniques; Iprindole; Lithium; Morphine; Norepinephrine; Nortriptyline; Opipramol; Rabbits; Succinimides; Time Factors

1974
Confirmed identification of biotransformed drugs of abuse in urine.
    American journal of clinical pathology, 1972, Volume: 57, Issue:1

    Topics: Amphetamine; Analgesics; Barbiturates; Biotransformation; Caffeine; Cannabis; Chromatography, Gas; Chromatography, Thin Layer; Codeine; Humans; Hydrogen-Ion Concentration; Imipramine; Indicators and Reagents; Methadone; Morphine; Nicotine; Pharmaceutical Preparations; Procaine; Skin; Spectrum Analysis; Substance-Related Disorders; Tranquilizing Agents

1972
Psychotropic drug influences on brain acetylcholine utilization.
    Psychopharmacologia, 1972, Volume: 25, Issue:4

    Topics: Acetylcholine; Animals; Antidepressive Agents; Brain; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Hemicholinium 3; Imipramine; Lysergic Acid Diethylamide; Male; Methotrimeprazine; Morphine; Pentobarbital; Phencyclidine; Rats; Rats, Inbred Strains; Scopolamine; Tranquilizing Agents

1972
Drug-induced suppression of conditioned hyperthermic and conditioned avoidance behavior response in rats.
    Psychopharmacologia, 1971, Volume: 20, Issue:2

    Topics: Animals; Avoidance Learning; Behavior, Animal; Chlorpromazine; Conditioning, Psychological; Fever; Imipramine; Morphine; Phentolamine; Rats; Thioridazine

1971
[Effect of psychotropic drugs on the emotional behavior of cats caused by the administration of acetylcholine into the central grey matter].
    Biulleten' eksperimental'noi biologii i meditsiny, 1971, Volume: 72, Issue:12

    Topics: Acetylcholine; Animals; Atropine; Behavior, Animal; Benactyzine; Cats; Chlordiazepoxide; Chlorpromazine; Haloperidol; Imipramine; Meprobamate; Morphine; Tranquilizing Agents; Trifluoperazine

1971
Aconitine-induced writhing: a method for assessment of analgesic activity.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:1

    Topics: Aconitum; Analgesics; Animals; Aspirin; Behavior, Animal; Chlorpromazine; Imipramine; Mephenesin; Methaqualone; Methods; Mice; Morphine; Phenoxybenzamine; Phenylbutazone; Phenytoin; Sodium Salicylate

1969
Neuropharmacological analysis of agonistic actions of cyclazocine in rabbits.
    Biological psychiatry, 1969, Volume: 1, Issue:4

    Topics: Analgesics; Animals; Azocines; Cyclazocine; Drug Synergism; Drug Tolerance; Electroencephalography; Female; Heroin; Imipramine; Male; Methamphetamine; Methods; Morphine; Motor Activity; Muscles; Narcotic Antagonists; Pentazocine; Physostigmine; Rats; Scopolamine; Stimulation, Chemical

1969
[Influence of some psychotropic drugs upon the action of morphine, dolantine and aminophenazone in white mice].
    Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, 1969, Volume: 24

    Topics: Aminopyrine; Animals; Drug Antagonism; Drug Synergism; Female; Imipramine; Male; Mice; Morphine; Nialamide; Silicon; Time Factors

1969
[Principles and risks of drug treatment of pain].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Aminopyrine; Analgesics; Antidepressive Agents; Antipyrine; Aspirin; Codeine; Dibenzazepines; Humans; Imipramine; Levallorphan; Levorphanol; Methadone; Morphine; Pain; Phenacetin; Phenylbutazone; Pyrazoles; Salicylamides; Salicylates; Sulfonic Acids

1969
Drug effects on gastric secretion and stress gastric hemorrhage in the rat.
    The American journal of digestive diseases, 1970, Volume: 15, Issue:2

    Topics: Animals; Atropine; Autonomic Agents; Brain; Cerebral Ventricles; Chlordiazepoxide; Chlorpromazine; Dimethyl Sulfoxide; Gastric Acidity Determination; Gastric Juice; Humans; Imidazoles; Imipramine; Injections, Intravenous; Morphine; Peptic Ulcer Hemorrhage; Psychophysiologic Disorders; Rats; Stress, Psychological; Vagotomy

1970
[Studies on anti-inflammatory agents. II. Analgesic and anti-edematous activities of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6, 7-tetrahydrothieno (2,3-c)pyridine (Y-3642)].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1970, Volume: 90, Issue:3

    Topics: Aminopyrine; Amphetamine; Analgesics; Animals; Anti-Inflammatory Agents; Edema; Imipramine; Male; Mice; Morphine; Pain; Papaverine; Phenylbutazone; Pyridines; Rats; Salicylates; Thiophenes

1970
Role of biogenic amines in morphine dependence in the rat.
    Life sciences. Pt. 1: Physiology and pharmacology, 1970, Jun-01, Volume: 9, Issue:11

    Topics: Animals; Brain; Dihydroxyphenylalanine; Dopamine; Female; Humans; Imipramine; Male; Methyltyrosines; Morphine; Nalorphine; Norepinephrine; Phenylalanine; Rats; Serotonin; Substance-Related Disorders; Thiocarbamates

1970
[The appearance of threat and flight reactions evoked by stimulation of the anterior hypothalamus of cats against a background of psychotropic drug action].
    Biulleten' eksperimental'noi biologii i meditsiny, 1970, Volume: 69, Issue:5

    Topics: Aggression; Animals; Benactyzine; Cats; Chlordiazepoxide; Chlorpromazine; Electric Stimulation; Escape Reaction; Haloperidol; Humans; Hypothalamus; Imipramine; Meprobamate; Morphine; Psychopharmacology; Trifluoperazine

1970
[Intraspecific aggressive behavior induced by apomorphine in the rat].
    Psychopharmacologia, 1970, Volume: 18, Issue:3

    Topics: Acepromazine; Age Factors; Aggression; Amitriptyline; Animals; Apomorphine; Atropine; Behavior, Animal; Caffeine; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Diazepam; Drug Antagonism; Electroshock; Environment; Haloperidol; Humans; Hydroxyzine; Imipramine; Male; Meprobamate; Morphine; Rats; Reserpine; Sex Factors; Sound; Species Specificity; Thiazines; Thioridazine

1970
Effects of various drugs on 3,4-dihydroxyphenylalanine (DL-DOPA)-induced excitation (agressive behavior) in mice.
    Toxicology and applied pharmacology, 1970, Volume: 17, Issue:3

    Topics: Aggression; Animals; Antidepressive Agents; Autonomic Agents; Behavior, Animal; Bretylium Compounds; Chlordiazepoxide; Chlorpromazine; Diazepam; Dihydroxyphenylalanine; Drug Antagonism; Haloperidol; Hexobarbital; Humans; Imipramine; Iproniazid; Male; Mice; Morphine; Oxazepam; Reserpine; Tranquilizing Agents; Tranylcypromine; Trifluoperazine

1970
[Effect of psychotropic substances on the behavior of cats, induced by administration of acetylcholine into the hypothalamus].
    Farmakologiia i toksikologiia, 1971, Volume: 34, Issue:1

    Topics: Acetylcholine; Action Potentials; Amygdala; Animals; Atropine; Behavior, Animal; Benactyzine; Cats; Chlordiazepoxide; Chlorpromazine; Depression, Chemical; Electroencephalography; Haloperidol; Hostility; Hypothalamus; Imipramine; Meprobamate; Morphine; Reticular Formation; Stimulation, Chemical; Tranquilizing Agents; Trifluoperazine

1971
The effects of drugs on the rate of development of fatigue in mice.
    Texas reports on biology and medicine, 1967,Winter, Volume: 25, Issue:4

    Topics: Amphetamine; Animals; Dextroamphetamine; Fatigue; Imipramine; Male; Methods; Mice; Morphine; Pentobarbital; Phenmetrazine; Stimulation, Chemical; Swimming

1967
[Pharmacologic changes in feeding behavior: food intake and rumination in sheep].
    Psychopharmacologia, 1968, Volume: 12, Issue:2

    Topics: Amphetamine; Animals; Apomorphine; Atropine; Behavior, Animal; Cerebral Cortex; Chlorpromazine; Digestion; Digitalis Glycosides; Eating; Imipramine; Iproniazid; Lanatosides; Mescaline; Methylphenidate; Morphine; Ouabain; Pentobarbital; Psychopharmacology; Reticulum; Rumen; Sheep; Theophylline

1968
Analgesic profile of tranquillizers in multiple screening tests in mice.
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 176, Issue:1

    Topics: Acetaminophen; Aminopyrine; Analgesics; Animals; Aspirin; Chlorpromazine; Codeine; Diazepam; Diphenhydramine; Electric Stimulation; Haloperidol; Hot Temperature; Hydroxyzine; Imipramine; Isocarboxazid; Male; Meprobamate; Mice; Morphine; Perphenazine; Phenobarbital; Phenothiazines; Promazine; Promethazine; Reserpine; Tetrabenazine; Thiopental; Time Factors; Tranquilizing Agents

1968
Potentiation of morphine analgesia by cocaine in mice.
    European journal of pharmacology, 1968, Volume: 5, Issue:1

    Topics: Amphetamine; Analgesia; Animals; Cocaine; Dibucaine; Drug Synergism; Female; Imipramine; Lidocaine; Male; Mice; Morphine; Norepinephrine; Phentolamine; Procaine; Rats; Reserpine

1968
The influence of imipramine on the "abstinence syndrome" to morphine in mice.
    International journal of neuropharmacology, 1968, Volume: 7, Issue:2

    Topics: Animals; Humans; Imipramine; Male; Mice; Morphine; Nalorphine; Postural Balance; Substance Withdrawal Syndrome

1968
The thyroid and the reactivity of the organism to drugs.
    Revue roumaine de physiologie, 1968, Volume: 5, Issue:1

    Topics: Amobarbital; Animals; Chlordiazepoxide; Drug Hypersensitivity; Hyperthyroidism; Imipramine; Male; Mice; Morphine; Reserpine; Thyroid Gland; Thyroid Hormones

1968
Inhibition of phospholipid-facilitated calcium transport by central nervous system-acting drugs.
    Biochemical pharmacology, 1969, Volume: 18, Issue:2

    Topics: Amphetamine; Analgesics; Animals; Biological Transport; Brain; Calcium; Calcium Isotopes; Carbon Isotopes; Cell Membrane; Chlordiazepoxide; Chlorpromazine; Guinea Pigs; Hydrogen-Ion Concentration; Imipramine; Metals; Morphine; Nalorphine; Narcotics; Pentobarbital; Phospholipids

1969
Thin-layer chromatographic detection of barbiturates, narcotics, and amphetamines in urine of patients receiving psychotropic drugs.
    Journal of chromatography, 1969, May-20, Volume: 41, Issue:3

    Topics: Amphetamine; Barbiturates; Chlorpromazine; Chromatography, Thin Layer; Cocaine; Codeine; Humans; Imipramine; Ion Exchange Resins; Meperidine; Methadone; Morphine; Narcotics; Quinine; Thioridazine; Trifluoperazine

1969
[Modification of central mechanisms of action by anticholinergics].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:1

    Topics: Aggression; Amphetamine; Animals; Apomorphine; Atropine; Biperiden; Bridged-Ring Compounds; Central Nervous System; Chlorpromazine; Depression, Chemical; Drug Synergism; Esters; Female; Hexobarbital; Humans; Imipramine; Male; Mice; Morphine; Nicotine; Parasympatholytics; Pentylenetetrazole; Perphenazine; Rats; Stimulation, Chemical; Strychnine; Tremorine

1969
Changes in the metabolism of 3,4-dihydroxyphenylethylamine (dopamine) in the striatum of the mouse induced by drugs.
    British journal of pharmacology and chemotherapy, 1966, Volume: 28, Issue:2

    Topics: Anesthetics; Animals; Behavior, Animal; Brain; Dopamine; Drug Antagonism; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Methylphenidate; Methyltyrosines; Mice; Mixed Function Oxygenases; Monoamine Oxidase; Morphine; Parasympatholytics; Parasympathomimetics; Pargyline; Phencyclidine; Phenylacetates; Pilocarpine; Probenecid; Reserpine; Tolazoline; Tranquilizing Agents; Tyrosine; Zoxazolamine

1966
Inhibition of evoked potentials by caudate stimulation and its antagonism by centrally acting drugs.
    International journal of neuropharmacology, 1967, Volume: 6, Issue:5

    Topics: Amphetamine; Amygdala; Animals; Bemegride; Caffeine; Cats; Caudate Nucleus; Cerebral Cortex; Chlorpromazine; Electric Stimulation; Electrophysiology; Evoked Potentials; Forelimb; Hippocampus; Hypothalamus; Imipramine; Medulla Oblongata; Mephenesin; Morphine; Neurons; Pentobarbital; Pentylenetetrazole; Picrotoxin; Reticular Formation; Strychnine; Thalamus

1967
New, simple method for the informative investigation of sedatives.
    Psychopharmacologia, 1967, Volume: 12, Issue:1

    Topics: Amphetamine; Animals; Chlordiazepoxide; Chlorpromazine; Diazepam; Escape Reaction; Glutethimide; Haloperidol; Hypnotics and Sedatives; Imipramine; Male; Meprobamate; Methadone; Methods; Mice; Morphine; Nialamide; Pentobarbital; Phenobarbital; Reserpine; Tubocurarine; Urethane

1967
Sensitivity in vivo of central alpha 2- and opiate receptors after chronic treatment with various antidepressants.
    Journal of neural transmission, 1982, Volume: 54, Issue:1-2

    Topics: Animals; Antidepressive Agents; Brompheniramine; Chlorpromazine; Clomipramine; Clonidine; Desipramine; Evoked Potentials; Imipramine; Iprindole; Locus Coeruleus; Male; Mianserin; Morphine; Neural Inhibition; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Opioid; Zimeldine

1982
Behavioural effects of hashish in mice in comparison with other psychoactive drugs.
    General pharmacology, 1982, Volume: 13, Issue:4

    Topics: Aggression; Amphetamine; Animals; Behavior, Animal; Cannabis; Chlorpromazine; Diazepam; Humans; Imipramine; Male; Mice; Mice, Inbred Strains; Morphine; Motor Activity; Psychotropic Drugs; Social Behavior

1982
[Comparison of the effects of several psychotropic drugs by gross behavioral observation on rhesus monkeys].
    Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1981, Volume: 1, Issue:1

    Topics: Amphetamines; Animals; Barbital; Behavior, Animal; Chlorpromazine; Cocaine; Diazepam; Female; Imipramine; Lysergic Acid Diethylamide; Macaca mulatta; Male; Morphine; Psychotropic Drugs

1981
Implication of endogenous opioid system in the learned helplessness model of depression.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Avoidance Learning; Depression; Electroshock; Endorphins; Enkephalins; Helplessness, Learned; Hydroxamic Acids; Imipramine; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neprilysin; Phenylalanine; Protease Inhibitors; Rats; Rats, Wistar

1995
Effects of morphine, naloxone, buprenorphine, butorphanol, haloperidol and imipramine on morphine withdrawal signs in cynomolgus monkeys.
    Psychopharmacology, 1994, Volume: 116, Issue:4

    Topics: Animals; Behavior, Animal; Buprenorphine; Butorphanol; Haloperidol; Imipramine; Macaca fascicularis; Male; Morphine; Morphine Dependence; Naloxone; Psychotropic Drugs; Substance Withdrawal Syndrome

1994
Effects of psychotropic drugs on impairment of acquisition of shuttle avoidance produced by pretreatment with pairs of tone signal and shock in mice.
    The Japanese journal of psychiatry and neurology, 1994, Volume: 48, Issue:3

    Topics: Animals; Avoidance Learning; Caffeine; Chlorpromazine; Diazepam; Electroshock; Imipramine; Male; Mice; Morphine; Nicotine; Psychotropic Drugs; Signal Detection, Psychological

1994
Fentanyl inhibits the uptake of [3H]noradrenaline in cultured neuronal cells.
    British journal of anaesthesia, 1993, Volume: 71, Issue:4

    Topics: Adrenal Gland Neoplasms; Animals; Dose-Response Relationship, Drug; Fentanyl; Humans; Imipramine; Morphine; Naloxone; Neuroblastoma; Neurons; Norepinephrine; Pheochromocytoma; Rats; Time Factors; Tumor Cells, Cultured

1993
Interaction of opioids with antidepressant-induced antinociception.
    Psychopharmacology, 1995, Volume: 122, Issue:4

    Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Clomipramine; Drug Combinations; Female; Imipramine; Male; Maprotiline; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pain Measurement; Random Allocation; Selective Serotonin Reuptake Inhibitors; Zimeldine

1995
Chronic antidepressant treatments increase cytochrome b mRNA levels in mouse cerebral cortex.
    Journal of molecular neuroscience : MN, 1997, Volume: 9, Issue:3

    Topics: Animals; Antidepressive Agents; Cerebral Cortex; Cytochrome b Group; Drug Administration Schedule; Electroshock; Gene Expression Regulation; Haloperidol; Imipramine; Injections, Intraperitoneal; Male; Mice; Morphine; RNA, Messenger

1997
GABA(B) receptor mechanism and imipramine-induced antinociception in ligated and non-ligated mice.
    European journal of pharmacology, 2000, Oct-27, Volume: 407, Issue:1-2

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Tricyclic; Baclofen; GABA Agonists; GABA Antagonists; Imipramine; Ligation; Male; Mice; Morphine; Organophosphorus Compounds; Pain Measurement; Receptors, GABA-B; Sciatic Nerve

2000
Effect of imipramine on tolerance to morphine antinociception in the formalin test.
    Pharmacology & toxicology, 2000, Volume: 87, Issue:3

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Disinfectants; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Formaldehyde; Imipramine; Injections, Intraperitoneal; Male; Mice; Morphine; Naloxone; Pain

2000
Effect of alpha-adrenoceptor agents on imipramine-induced antinociception in nerve-ligated mice.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2001, Volume: 11, Issue:2

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Imipramine; Ligation; Male; Mice; Morphine; Pain Measurement; Sciatic Nerve; Sciatic Neuropathy

2001
Evaluation of the marmoset as a model species for drug glucuronidation.
    Xenobiotica; the fate of foreign compounds in biological systems, 2001, Volume: 31, Issue:12

    Topics: Animals; Callithrix; Female; Glucuronates; Imipramine; Inactivation, Metabolic; Kidney; Male; Microsomes, Liver; Models, Animal; Morphine; Propofol; Rats; Rats, Sprague-Dawley; Species Specificity

2001
Experimental conditions for the continuous subcutaneous infusion of four central analgesics in rats.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 72, Issue:4

    Topics: Acetates; Amines; Analgesics; Anesthetics, Dissociative; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Chronic Disease; Convulsants; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Hypothermia; Imipramine; Infusion Pumps, Implantable; Ketamine; Male; Morphine; Pain; Pain Measurement; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Solubility; Tetrabenazine

2002
Effect of imipramine on the expression and acquisition of morphine-induced conditioned place preference in mice.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 73, Issue:4

    Topics: Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Imipramine; Male; Mice; Morphine; Motor Activity

2002
Large-amplitude 5-HT1A receptor activation: a new mechanism of profound, central analgesia.
    Neuropharmacology, 2002, Volume: 43, Issue:6

    Topics: Acetates; Adrenergic Uptake Inhibitors; Amines; Aminopyridines; Analgesia; Analgesics; Animals; Cells, Cultured; CHO Cells; Cricetinae; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Synergism; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hyperalgesia; Imipramine; Ketamine; Male; Morphine; Pain; Pain Measurement; Pain Threshold; Piperidines; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Time Factors; Transfection

2002
Effects of imipramine on the expression and development of morphine dependence in mice.
    European journal of pharmacology, 2003, Jul-18, Volume: 473, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Clonidine; Dose-Response Relationship, Drug; Imipramine; Injections, Subcutaneous; Male; Mice; Morphine; Morphine Dependence; Motor Activity; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Yohimbine

2003
Cause of death in narcotic intoxication in recent years.
    Danish medical bulletin, 1963, Volume: 10

    Topics: Cause of Death; Chlorprothixene; Heart Diseases; Humans; Imipramine; Kidney Diseases; Lung Diseases; Meperidine; Morphine; Narcotics; Shock

1963
Effects of morphine and Tofranil on the incorporation of phosphate (32P) into phospolipids of rat brain slices.
    Biochemical pharmacology, 1963, Volume: 12

    Topics: Animals; Brain; Imipramine; Morphine; Phosphates; Phospholipids; Rats

1963
HYPERMOTILITY EVOKED BY LESIONS OF THE SEPTUM AND ANTERIOR HYPOTHALAMUS.
    Acta physiologica Academiae Scientiarum Hungaricae, 1963, Volume: 23

    Topics: Aminopyrine; Amygdala; Atropine; Body Temperature; Caudate Nucleus; Cerebral Ventricles; Chlorpromazine; Electrocoagulation; Ephedrine; Hexobarbital; Hippocampus; Hypothalamus; Hypothalamus, Anterior; Imipramine; Iproniazid; Metabolism; Morphine; Movement Disorders; Physostigmine; Rats; Research; Reserpine; Scopolamine

1963
A SIMPLE SCREENING PROCEDURE FOR IMIPRAMINE-LIKE ANTIDEPRESSANT AGENTS.
    Life sciences (1962), 1963, Volume: 10

    Topics: 5-Hydroxytryptophan; Amitriptyline; Amphetamine; Amphetamines; Antidepressive Agents; Atropine; Bemegride; Chlorpromazine; Diethylpropion; Dihydroxyphenylalanine; Epinephrine; Hypothermia; Hypothermia, Induced; Imipramine; Indoles; Iproniazid; Lysergic Acid Diethylamide; Mice; Morphine; Nialamide; Pentylenetetrazole; Pharmacology; Phenelzine; Promethazine; Research; Reserpine

1963
Drug administration to cerebral cortex of freely moving dogs.
    Science (New York, N.Y.), 1962, Mar-30, Volume: 135, Issue:3509

    Topics: Amobarbital; Animals; Cerebral Cortex; Dogs; Imipramine; Morphine

1962
Cocaine and other indirect-acting monoamine agonists differentially attenuate a naltrexone discriminative stimulus in morphine-treated rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 308, Issue:1

    Topics: Amphetamine; Animals; Biogenic Monoamines; Cocaine; Discrimination Learning; Disease Models, Animal; Dopamine Agents; Dopamine Uptake Inhibitors; Drug Interactions; Imipramine; Macaca mulatta; Morphine; Morphine Dependence; Naltrexone; Narcotics; Substance Withdrawal Syndrome

2004
Interactions of acute morphine with chronic imipramine and fluvoxamine treatment on the antinociceptive effect in arthritic rats.
    Neuroscience letters, 2003, Nov-27, Volume: 352, Issue:1

    Topics: Analgesics; Animals; Arthritis, Experimental; Drug Interactions; Fluvoxamine; Imipramine; Male; Morphine; Pain Measurement; Rats; Rats, Wistar

2003
Eye-wiping test: a sensitive animal model for acute trigeminal pain studies.
    Brain research. Brain research protocols, 2005, Volume: 16, Issue:1-3

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Behavior, Animal; Cornea; Data Interpretation, Statistical; Disease Models, Animal; Eye; Imipramine; Irritants; Male; Morphine; Pain; Pain Measurement; Rats; Rats, Wistar; Reaction Time; Salicylates; Sodium Chloride; Trigeminal Neuralgia

2005
Suppressive effect of imipramine on vincristine-induced mechanical allodynia in mice.
    Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:7

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Tricyclic; Antineoplastic Agents, Phytogenic; Hyperalgesia; Imipramine; Male; Mice; Mice, Inbred ICR; Morphine; Pain Measurement; Sciatic Neuropathy; Vincristine

2009
Interaction between behavioral despair and addictive behaviors in rats.
    Physiology & behavior, 2011, Jan-10, Volume: 102, Issue:1

    Topics: Animals; Behavior, Addictive; Choice Behavior; Conditioning, Classical; Depression; Disease Models, Animal; Drug Interactions; Food; Imipramine; Male; Morphine; Motor Activity; Rats; Rats, Sprague-Dawley; Swimming; Time Factors

2011
Hepatic microsomal UDP-glucuronosyltransferase (UGT) activities in the microminipig.
    Biopharmaceutics & drug disposition, 2014, Volume: 35, Issue:6

    Topics: Adult; Aged; Animals; Chromatography, Liquid; Dogs; Estradiol; Female; Glucuronides; Glucuronosyltransferase; Humans; Imipramine; Macaca fascicularis; Male; Mice, Inbred ICR; Microsomes, Liver; Middle Aged; Morphine; Propofol; Rats, Sprague-Dawley; Serotonin; Species Specificity; Swine; Swine, Miniature; Tandem Mass Spectrometry; Young Adult; Zidovudine

2014
Effects of Adjuvant Analgesics on Cerebral Ischemia-Induced Mechanical Allodynia.
    Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:5

    Topics: Amines; Analgesics; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Brain Ischemia; Carbamazepine; Chemotherapy, Adjuvant; Cyclohexanecarboxylic Acids; Cyclopropanes; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Imipramine; Indomethacin; Male; Mexiletine; Mice; Milnacipran; Morphine; Neuralgia; Paroxetine; Selective Serotonin Reuptake Inhibitors

2016
Irinotecan Alters the Disposition of Morphine Via Inhibition of Organic Cation Transporter 1 (OCT1) and 2 (OCT2).
    Pharmaceutical research, 2018, Oct-25, Volume: 35, Issue:12

    Topics: Amitriptyline; Animals; Drug Interactions; Fluoxetine; HEK293 Cells; Humans; Imipramine; Irinotecan; Mice, Inbred C57BL; Morphine; Narcotics; Ondansetron; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Tissue Distribution; Verapamil

2018