imipramine and mirtazapine

imipramine has been researched along with mirtazapine in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	8 (21.05)	18.2507
2000's	19 (50.00)	29.6817
2010's	9 (23.68)	24.3611
2020's	2 (5.26)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Buck, LB; Petrascheck, M; Ye, X	1
Lombardo, F; Obach, RS; Waters, NJ	1
Kenny, PW; Toulmin, A; Wood, JM	1
Ahman, M; Holmén, AG; Wan, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Alix, K; Dukat, M; Khatri, S; Schulte, MK; Worsham, J	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Gubbels, DG; Peeters, BW; van der Heijden, R; Vanderheyden, PM	1
Bruijn, JA; de Man, KJ; Man in 't Veld, AJ; Pepplinkhuizen, L; Tulen, JH; van den Meiracker, AH	1
Bruijn, JA; Moleman, P; Mulder, PG; van de Wetering, BJ; van den Broek, WW; van der Mast, RC; van Hulst, AM	1
Pinder, RM; Zivkov, M	1
Barkin, RL; Fawcett, J	1
Bruijn, JA; Moleman, P; Mulder, PG; van den Broek, WW	3
Keller, MB	1
Biggio, G; Dazzi, L; Jentsch, JD; Ladu, S; Pira, L; Rivano, A; Spiga, F; Vacca, G	1
Biggio, G; Dazzi, L; Ladu, S; Pisu, MG; Serra, M; Vacca, G	1
Biggio, G; Dazzi, L; Jentsch, JD; Pisu, MG; Serra, M; Spiga, F	1
Biggio, G; Dazzi, L; Ladu, S; Pira, L; Rivano, A; Spiga, F; Vacca, G	1
Bateman, DN; Chick, J; Good, AM; Kelly, CA; Masterton, G	1
Birkenhäger, TK; Bruijn, JA; Moleman, P; van den Broek, WW; Vulto, AG	1
Legutko, B; Rogóz, Z; Skuza, G	1
Akbiyik, DI; Alkis, N; Cankurtaran, ES; Ozalp, E; Soygur, H; Turhan, L	1
Birkenhäger, TK; Bruijn, JA; Mulder, PG; Sukul, YR; van den Broek, WW	1
Fisar, Z; Hroudová, J; Raboch, J	1
Clarke, G; Cryan, JF; Dinan, TG; Griffin, BT; O'Brien, FE	1
Cipriani, A; Coghill, D; Cohen, D; Cuijpers, P; Del Giovane, C; Hazell, P; Hetrick, SE; Leucht, S; Liu, L; Liu, Y; Michael, KD; Pu, J; Qin, B; Ravindran, AV; Whittington, C; Xie, P; Yang, L; Zhang, Y; Zhou, X	1
Engel, D; Gabilan, NH; Lieberknecht, V; Rodrigues, ALS	1
Koziorowski, M; Mytych, J; Sołek, P; Tabęcka-Łonczyńska, A	1

Reviews

4 review(s) available for imipramine and mirtazapine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Efficacy issues with antidepressants. The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 6 Topics: Absenteeism; Age Factors; Amitriptyline; Antidepressive Agents; Combined Modality Therapy; Controlled Clinical Trials as Topic; Depressive Disorder; Follow-Up Studies; Humans; Imipramine; Mianserin; Mirtazapine; Outcome Assessment, Health Care; Placebos; Psychiatric Status Rating Scales; Psychotherapy; Severity of Illness Index; Treatment Outcome; Work	1997
The long-term treatment of depression. The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 17 Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Chronic Disease; Combined Modality Therapy; Depressive Disorder; Drug Administration Schedule; Humans; Imipramine; Mianserin; Mirtazapine; Psychotherapy; Secondary Prevention; Selective Serotonin Reuptake Inhibitors	1999
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis. Lancet (London, England), 2016, Aug-27, Volume: 388, Issue:10047 Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Confounding Factors, Epidemiologic; Depressive Disorder, Major; Desipramine; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Evidence-Based Medicine; Fluoxetine; Humans; Imipramine; Mianserin; Mirtazapine; Nortriptyline; Paroxetine; Piperazines; Randomized Controlled Trials as Topic; Research Design; Sertraline; Treatment Outcome; Triazoles; Venlafaxine Hydrochloride	2016

Trials

6 trial(s) available for imipramine and mirtazapine

Article	Year
Cardiovascular variability in major depressive disorder and effects of imipramine or mirtazapine (Org 3770). Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:2 Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Arousal; Blood Pressure; Depressive Disorder; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Imipramine; Male; Mianserin; Middle Aged; Mirtazapine; Parasympathetic Nervous System; Signal Processing, Computer-Assisted; Sympathetic Nervous System; Vagus Nerve	1996
A double-blind, fixed blood-level study comparing mirtazapine with imipramine in depressed in-patients. Psychopharmacology, 1996, Volume: 127, Issue:3 Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Mianserin; Middle Aged; Mirtazapine; Psychiatric Status Rating Scales	1996
Comparison of 2 treatment strategies for depressed inpatients: imipramine and lithium addition or mirtazapine and lithium addition. The Journal of clinical psychiatry, 1998, Volume: 59, Issue:12 Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Confidence Intervals; Depressive Disorder; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Hospitalization; Humans; Imipramine; Lithium; Male; Mianserin; Middle Aged; Mirtazapine; Patient Dropouts; Research Design; Survival Analysis; Treatment Outcome	1998
Depressed in-patients respond differently to imipramine and mirtazapine. Pharmacopsychiatry, 1999, Volume: 32, Issue:3 Topics: Adrenergic alpha-Antagonists; Adult; Analysis of Variance; Antidepressive Agents, Tricyclic; Anxiety; Chi-Square Distribution; Depression; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Likelihood Functions; Male; Mianserin; Middle Aged; Mirtazapine; Sleep Wake Disorders; Treatment Outcome	1999
Imipramine dose in relation to therapeutic plasma level: are clinical trials using imipramine as a positive control flawed? Psychopharmacology, 2005, Volume: 181, Issue:3 Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fluvoxamine; Humans; Imipramine; Male; Metabolic Clearance Rate; Mianserin; Middle Aged; Mirtazapine; Treatment Outcome	2005
Mirtazapine improves sleep and lowers anxiety and depression in cancer patients: superiority over imipramine. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2008, Volume: 16, Issue:11 Topics: Adaptation, Psychological; Adjustment Disorders; Adrenergic alpha-Antagonists; Adult; Antidepressive Agents, Tricyclic; Anxiety Disorders; Depressive Disorder, Major; Female; Histamine H1 Antagonists; Humans; Imipramine; Male; Mianserin; Middle Aged; Mirtazapine; Neoplasms; Pain; Pain Measurement; Psychometrics; Self-Assessment; Single-Blind Method; Sleep; Sleep Wake Disorders; Stress, Psychological	2008

Other Studies

28 other study(ies) available for imipramine and mirtazapine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
An antidepressant that extends lifespan in adult Caenorhabditis elegans. Nature, 2007, Nov-22, Volume: 450, Issue:7169 Topics: Aging; Animals; Antidepressive Agents; Caenorhabditis elegans; Caloric Restriction; Humans; Longevity; Methiothepin; Mianserin; Octopamine; Receptors, Biogenic Amine; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Starvation	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Toward prediction of alkane/water partition coefficients. Journal of medicinal chemistry, 2008, Jul-10, Volume: 51, Issue:13 Topics: Alkanes; Central Nervous System; Molecular Structure; Static Electricity; Surface Properties; Water	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3 Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
2-Amino-6-chloro-3,4-dihydroquinazoline: A novel 5-HT3 receptor antagonist with antidepressant character. Bioorganic & medicinal chemistry letters, 2013, Nov-01, Volume: 23, Issue:21 Topics: Amination; Animals; Antidepressive Agents; Anura; Halogenation; Hindlimb Suspension; Mice; Quinazolines; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Effects of chronic antidepressant treatment on the hypothalamic-pituitary-adrenal axis of Wistar rats. Annals of the New York Academy of Sciences, 1994, Nov-30, Volume: 746 Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Body Weight; Corticosterone; Hippocampus; Hypothalamo-Hypophyseal System; Imipramine; Kinetics; Male; Mianserin; Mirtazapine; Pituitary-Adrenal System; Rats; Rats, Wistar; Receptors, Glucocorticoid; Reference Values	1994
Imipramine and mirtazapine are less effective than expected. Psychopharmacology, 1997, Volume: 129, Issue:3 Topics: Antidepressive Agents, Tricyclic; Depressive Disorder; Humans; Imipramine; Mianserin; Mirtazapine	1997
Inhibition of stress- or anxiogenic-drug-induced increases in dopamine release in the rat prefrontal cortex by long-term treatment with antidepressant drugs. Journal of neurochemistry, 2001, Volume: 76, Issue:4 Topics: Animals; Antidepressive Agents; Anxiety; Carbolines; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Electroshock; GABA Antagonists; Imipramine; Male; Mianserin; Microdialysis; Mirtazapine; Neurons; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Time Factors	2001
Long-term treatment with antidepressant drugs reduces the sensitivity of cortical cholinergic neurons to the activating actions of stress and the anxiogenic drug FG 7142. Neuropharmacology, 2001, Volume: 41, Issue:2 Topics: Acetylcholine; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Carbolines; Cholinergic Fibers; GABA Antagonists; Imipramine; Male; Mianserin; Mirtazapine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Stress, Physiological	2001
Treatment of mood-congruent psychotic depression with imipramine. Journal of affective disorders, 2001, Volume: 66, Issue:2-3 Topics: Adolescent; Adult; Affect; Aged; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Imipramine; Male; Mianserin; Middle Aged; Mirtazapine; Personality Inventory; Psychiatric Status Rating Scales; Psychotic Disorders; Treatment Outcome	2001
Prevention of the stress-induced increase in frontal cortical dopamine efflux of freely moving rats by long-term treatment with antidepressant drugs. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2001, Volume: 11, Issue:5 Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Dopamine; Electroshock; Extracellular Space; Frontal Lobe; Imipramine; Male; Mianserin; Microdialysis; Mirtazapine; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Steroids; Stress, Psychological	2001
Chronic treatment with imipramine or mirtazapine antagonizes stress- and FG7142-induced increase in cortical norepinephrine output in freely moving rats. Synapse (New York, N.Y.), 2002, Volume: 43, Issue:1 Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Carbolines; Cerebral Cortex; Depression; Dose-Response Relationship, Drug; Drug Administration Schedule; Electric Stimulation; GABA Antagonists; Imipramine; Male; Mianserin; Mirtazapine; Norepinephrine; Rats; Receptors, GABA-A; Stress, Physiological	2002
Are selective serotonin re-uptake inhibitors associated with an increased risk of self-harm by antidepressant overdose? European journal of clinical pharmacology, 2004, Volume: 60, Issue:3 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Citalopram; Cyclohexanols; Doxepin; Drug Overdose; Drug Prescriptions; Emergency Service, Hospital; Female; Fluoxetine; Humans; Imipramine; Information Services; Male; Mianserin; Mirtazapine; Paroxetine; Patient Admission; Patient Readmission; Poison Control Centers; Retrospective Studies; Risk Assessment; Scotland; Selective Serotonin Reuptake Inhibitors; Self-Injurious Behavior; Sertraline; Trazodone; Venlafaxine Hydrochloride	2004
Repeated treatment with mirtazepine induces brain-derived neurotrophic factor gene expression in rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2005, Volume: 56, Issue:4 Topics: Amphetamines; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Dose-Response Relationship, Drug; Hippocampus; Imipramine; Male; Mianserin; Mirtazapine; Rats; Rats, Wistar; RNA, Messenger; Serotonin Receptor Agonists; Time Factors	2005
Trait anxiety and defensive functioning in relation to antidepressant treatment outcome. Psychopathology, 2009, Volume: 42, Issue:6 Topics: Adolescent; Adult; Aged; Antidepressive Agents; Anxiety Disorders; Depressive Disorder; Female; Humans; Imipramine; Male; Mianserin; Middle Aged; Mirtazapine; Patient Selection; Personality Assessment; Psychiatric Status Rating Scales; Regression Analysis; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome	2009
Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers. Neuro endocrinology letters, 2010, Volume: 31, Issue:5 Topics: Affect; Amitriptyline; Animals; Antidepressive Agents; Antimanic Agents; Benzodiazepines; Cerebral Cortex; Citalopram; Clorgyline; Cocaine; Cyclohexanols; Desipramine; Fluoxetine; Imipramine; In Vitro Techniques; Iproniazid; Lithium; Mianserin; Mirtazapine; Mitochondria; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Morpholines; Olanzapine; Pargyline; Reboxetine; Swine; Thiazepines; Valproic Acid; Venlafaxine Hydrochloride	2010
Human P-glycoprotein differentially affects antidepressant drug transport: relevance to blood-brain barrier permeability. The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:10 Topics: Amitriptyline; Animals; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Capillary Permeability; Dogs; Duloxetine Hydrochloride; Fluoxetine; Humans; Imipramine; Madin Darby Canine Kidney Cells; Mianserin; Mirtazapine; Thiophenes; Transfection	2013
Neuroprotective effects of mirtazapine and imipramine and their effect in pro- and anti-apoptotic gene expression in human neuroblastoma cells. Pharmacological reports : PR, 2020, Volume: 72, Issue:3 Topics: Apoptosis; bcl-Associated Death Protein; Cell Line, Tumor; Cell Survival; Humans; Imipramine; Mirtazapine; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Tumor Suppressor Protein p53	2020
Molecular Consequences of Depression Treatment: A Potential In Vitro Mechanism for Antidepressants-Induced Reprotoxic Side Effects. International journal of molecular sciences, 2021, Nov-01, Volume: 22, Issue:21 Topics: Amitriptyline; Animals; Antidepressive Agents; Antipsychotic Agents; Cell Line; Escitalopram; Fluoxetine; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation; Imipramine; Male; Mice; Micronuclei, Chromosome-Defective; Mirtazapine; Models, Biological; Olanzapine; Organ Specificity; Reboxetine; Reproduction; Signal Transduction; Spermatogenesis; Telomeric Repeat Binding Protein 1; Telomeric Repeat Binding Protein 2; Time Factors; Venlafaxine Hydrochloride	2021