imipramine and milnacipran

imipramine has been researched along with milnacipran in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.70)18.7374
1990's4 (17.39)18.2507
2000's11 (47.83)29.6817
2010's6 (26.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baba, S; Horisawa, T; Kato, T; Kinomura, N; Kodo, T; Koyama, K; Masumoto, S; Matsumoto, K; Matsumoto, Y; Oki, H; Yabuuchi, K; Yoshinaga, H1
Briley, M; Moret, C2
Kawasaki, H; Nuki, C; Takasaki, K; Tasaki, H; Urabe, M; Yamamoto, R1
Bauer, M; Fauran-Clavel, MJ; LaCabanne, C; Lamure, A; Megret, C1
Adamantidis, MM; Dupuis, BA; Rouet, RH; Tisne-Versailles, J; Vincent, A1
Chartres, JP; Léger, JM; Pezous, N; Plétan, Y; Pujol-Domenech, J; Tignol, J; Tonelli, I; Tournoux, A1
Hashimoto, S; Hattori, T; Kawasaki, K; Kitamura, Y; Miki, N; Mochizuki, D; Otsuka, Y; Tsujita, R; Yamada, S1
Barbagli, B; Boissard, R; Fort, P; Gervasoni, D; Henninot, V; Luppi, PH; Panconi, E1
Ferrey, G; Tournoux, A; Van Amerongen, AP1
Conesa, A; Lopez-Ibor, JJ1
Aoki, M; Chiba, H; Harada, Y; Matsumiya, T; Nohara, J; Takeda, H; Tsuji, M1
Hazui, T; Hori, S; Matsuo, N; Miki, A; Nakano, M; Ohtani, H; Sawada, Y; Suzuki, Y; Yagi, H; Yamamoto, A1
Inoue, T; Iwamoto, N; Izumi, T; Kato, A; Kitaichi, Y; Koyama, T1
Hayashi, H; Sukma, M; Tanaka, K; Tohda, M1
Bantsiele, GB; Bentué-Ferrer, D; Bourin, M; Laviolle, B; Reymann, JM; Saïkali, S1
Aburakawa, Y; Aizawa, H; Hasebe, N; Kwak, S; Sawada, J; Yamashita, T1
Adachi-Akahane, S; Hoshiai, K; Koizumi, S; Matsumoto, M; Mitsumori, Y; Nagayama, Y; Nakamura, Y; Sugiyama, A1
Nowak, G; Pilc, A; Poleszak, E; Popik, P; Siwek, A; Szewczyk, B; Wolak, M1
Harada, S; Matsuura, W; Tokuyama, S1
Andricopulo, AD; Moda, TL; Montanari, CA1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for imipramine and milnacipran

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for imipramine and milnacipran

ArticleYear
Double-blind study of the efficacy and safety of milnacipran and imipramine in elderly patients with major depressive episode.
    Acta psychiatrica Scandinavica, 1998, Volume: 97, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Aged; Aged, 80 and over; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cyclopropanes; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Imipramine; Male; Milnacipran; Personality Inventory; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

1998
A randomised, double-blind comparison of milnacipran and imipramine in the treatment of depression.
    Journal of affective disorders, 2002, Volume: 72, Issue:1

    Topics: Adult; Aged; Antidepressive Agents; Cyclopropanes; Depressive Disorder, Major; Double-Blind Method; Drug Tolerance; Female; Follow-Up Studies; Humans; Imipramine; Male; Middle Aged; Milnacipran

2002
A comparative study of milnacipran and imipramine in the treatment of major depressive disorder.
    Current medical research and opinion, 2004, Volume: 20, Issue:6

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Cyclopropanes; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Milnacipran; Treatment Outcome

2004

Other Studies

19 other study(ies) available for imipramine and milnacipran

ArticleYear
Discovery of SMP-304, a novel benzylpiperidine derivative with serotonin transporter inhibitory activity and 5-HT
    Bioorganic & medicinal chemistry, 2017, 01-01, Volume: 25, Issue:1

    Topics: Animals; Antidepressive Agents; Cytochrome P-450 CYP2D6 Inhibitors; Dioxanes; Drug Partial Agonism; Humans; Male; Piperidines; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Serotonin Plasma Membrane Transport Proteins

2017
Effect of antidepressant drugs on monoamine synthesis in brain in vivo.
    Neuropharmacology, 1992, Volume: 31, Issue:7

    Topics: Animals; Antidepressive Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Citalopram; Clorgyline; Cyclopropanes; Desipramine; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Haloperidol; Hydrazines; Imipramine; Male; Milnacipran; Norepinephrine; Organ Specificity; Parietal Lobe; Rats; Rats, Wistar; Serotonin; Tyrosine 3-Monooxygenase

1992
[Electroencephalographic and cardiovascular effects of milnaciplan hydrochloride (TN-912), a novel antidepressant].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1991, Volume: 98, Issue:5

    Topics: Animals; Antidepressive Agents; Blood Pressure; Brain; Cyclopropanes; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Electroencephalography; Guinea Pigs; Heart Rate; Imipramine; In Vitro Techniques; Male; Maprotiline; Milnacipran; Myocardial Contraction; Rats; Rats, Inbred Strains; Respiration

1991
Differential scanning calorimetry study of the interaction of antidepressant drugs, noradrenaline, and 5-hydroxytryptamine with a membrane model.
    Journal of pharmaceutical sciences, 1990, Volume: 79, Issue:10

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Antidepressive Agents; Buffers; Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Physical; Cyclopropanes; Imipramine; Membranes, Artificial; Milnacipran; Models, Theoretical; Norepinephrine; Octanols; Piperidines; Serotonin; Solubility; Temperature

1990
Comparative in vivo and in vitro study of the cardiac effects of midalcipran and imipramine.
    Fundamental & clinical pharmacology, 1989, Volume: 3, Issue:3

    Topics: Action Potentials; Animals; Antidepressive Agents; Cyclopropanes; Electrophysiology; Female; Guinea Pigs; Heart; Imipramine; In Vitro Techniques; Infusions, Intravenous; Male; Membrane Potentials; Milnacipran; Myocardial Contraction; Papillary Muscles; Potassium

1989
High- and low-affinity binding of [3H]imipramine in rat hypothalamus.
    Journal of neurochemistry, 1986, Volume: 47, Issue:5

    Topics: Amitriptyline; Animals; Citalopram; Clomipramine; Cyclopropanes; Hypothalamus; Imipramine; Kinetics; Male; Milnacipran; Paroxetine; Piperidines; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Sodium

1986
Neurochemical and behavioural characterization of milnacipran, a serotonin and noradrenaline reuptake inhibitor in rats.
    Psychopharmacology, 2002, Volume: 162, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Behavior, Animal; Binding, Competitive; Brain Chemistry; Conditioning, Psychological; Cyclopropanes; Dose-Response Relationship, Drug; Fear; Fluoxetine; Fluvoxamine; Imipramine; Male; Maprotiline; Microdialysis; Milnacipran; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Prefrontal Cortex; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Cell Surface; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Swimming; Synaptosomes; Time Factors

2002
Effect of chronic treatment with milnacipran on sleep architecture in rats compared with paroxetine and imipramine.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 73, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Behavior, Animal; Body Weight; Cyclopropanes; Imipramine; Male; Milnacipran; Paroxetine; Rats; Selective Serotonin Reuptake Inhibitors; Sleep; Sleep Stages; Sleep, REM; Wakefulness

2002
Antidepressants enhance the antinociceptive effects of carbamazepine in the acetic acid-induced writhing test in mice.
    European journal of pharmacology, 2006, Nov-21, Volume: 550, Issue:1-3

    Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Carbamazepine; Cyclopropanes; Fluvoxamine; Imipramine; Male; Mice; Mice, Inbred ICR; Milnacipran; Pain; Pain Measurement

2006
Piloerection induced by replacing fluvoxamine with milnacipran.
    British journal of clinical pharmacology, 2007, Volume: 63, Issue:6

    Topics: Adult; Antidepressive Agents; Cyclopropanes; Female; Fluvoxamine; Humans; Imipramine; Milnacipran; Models, Biological; Norepinephrine; Panic Disorder; Piloerection

2007
Effects of co-administration of antidepressants and monoamine oxidase inhibitors on 5-HT-related behavior in rats.
    European journal of pharmacology, 2007, Jun-22, Volume: 565, Issue:1-3

    Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Cyclopropanes; Drug Interactions; Imipramine; Male; Mianserin; Milnacipran; Monoamine Oxidase Inhibitors; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Syndrome

2007
BNIP-3: a novel candidate for an intrinsic depression-related factor found in NG108-15 cells treated with Hochu-ekki-to, a traditional oriental medicine, or typical antidepressants.
    Neuroscience research, 2008, Volume: 62, Issue:1

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Apoptosis; Brain; Chromatography, High Pressure Liquid; Cyclopropanes; Depressive Disorder; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Gene Expression Profiling; Gene Expression Regulation; Hybridomas; Imipramine; Medicine, East Asian Traditional; Membrane Proteins; Mianserin; Mice; Milnacipran; Mitochondrial Proteins; Neurons; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Tumor Cells, Cultured; Up-Regulation

2008
Behavioral effects of four antidepressants on an ischemic rat model of emotional disturbances.
    Behavioural brain research, 2009, Aug-12, Volume: 201, Issue:2

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Anxiety Disorders; Behavior, Animal; Brain Ischemia; Cyclopropanes; Depressive Disorder; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Fluvoxamine; Hippocampus; Imipramine; Immobility Response, Tonic; Male; Milnacipran; Motor Activity; Rats; Rats, Wistar

2009
Effects of antidepressants on GluR2 Q/R site-RNA editing in modified HeLa cell line.
    Neuroscience research, 2009, Volume: 64, Issue:3

    Topics: Adenosine Deaminase; Amitriptyline; Amyotrophic Lateral Sclerosis; Antidepressive Agents; Arginine; Cyclopropanes; Desipramine; Fluoxetine; Fluvoxamine; Glutamine; HeLa Cells; Humans; Imipramine; Milnacipran; Morpholines; Paroxetine; Reboxetine; Receptors, AMPA; RNA Editing; RNA-Binding Proteins; RNA, Messenger

2009
In vivo canine model comparison of cardiovascular effects of antidepressants milnacipran and imipramine.
    Cardiovascular toxicology, 2010, Volume: 10, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Tricyclic; Cyclopropanes; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiologic Techniques, Cardiac; Female; Heart Conduction System; Hemodynamics; Imipramine; Infusions, Intravenous; Long QT Syndrome; Male; Milnacipran; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Time Factors; Ventricular Function

2010
Involvement of NMDA and AMPA receptors in the antidepressant-like activity of antidepressant drugs in the forced swim test.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Animals; Antidepressive Agents; Citalopram; Cyclopropanes; Imipramine; Immobility Response, Tonic; Male; Mice; Milnacipran; Morpholines; Motor Activity; N-Methylaspartate; Oxazines; Quinoxalines; Reboxetine; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate

2013
Effects of Adjuvant Analgesics on Cerebral Ischemia-Induced Mechanical Allodynia.
    Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:5

    Topics: Amines; Analgesics; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Brain Ischemia; Carbamazepine; Chemotherapy, Adjuvant; Cyclohexanecarboxylic Acids; Cyclopropanes; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Imipramine; Indomethacin; Male; Mexiletine; Mice; Milnacipran; Morphine; Neuralgia; Paroxetine; Selective Serotonin Reuptake Inhibitors

2016
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results

2011