imipramine and mifepristone

imipramine has been researched along with mifepristone in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19902 (15.38)18.7374
1990's2 (15.38)18.2507
2000's3 (23.08)29.6817
2010's6 (46.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bree, F; Durand, G; Gardier, A; Rouzeau, JD; Tillement, JP1
Baumann, P; Bree, F; Duche, JC; Eap, CB; Tillement, JP1
Duche, JC; Gomas, E; Herve, F; Tillement, JP1
Boukef, MF; Duché, JC; Jolliet-Riant, P; Simon, N; Tillement, JP1
Budziszewska, B; Jaworska-Feil, L; Kajta, M; Lasoń, W1
Huang, SD; Jiang, HD; Li, J; Sun, DL; Wu, PS; Ye, YJ1
Flak, JN; Herman, JP; McKlveen, J; Myers, B; Rice, T; Solomon, MB; Ulrich-Lai, Y; Wick, D; Wulsin, AC1

Reviews

1 review(s) available for imipramine and mifepristone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

12 other study(ies) available for imipramine and mifepristone

ArticleYear
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
    Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18

    Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride

2005
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of drug binding capacities of three AAG glycan variants of human origin.
    Progress in clinical and biological research, 1989, Volume: 300

    Topics: Dialysis; Estrenes; Humans; Imipramine; Immunodiffusion; Mifepristone; Orosomucoid; Pharmaceutical Preparations; Polysaccharides; Warfarin

1989
Comparison of drug binding capacities of two AAG peptidic variants of human origin.
    Progress in clinical and biological research, 1989, Volume: 300

    Topics: Dialysis; Dose-Response Relationship, Drug; Estrenes; Genetic Variation; Humans; Imipramine; In Vitro Techniques; Mifepristone; Orosomucoid; Sialic Acids

1989
Evidence for differences in the binding of drugs to the two main genetic variants of human alpha 1-acid glycoprotein.
    British journal of clinical pharmacology, 1993, Volume: 36, Issue:3

    Topics: Genetic Variation; Humans; Imipramine; In Vitro Techniques; Mifepristone; Orosomucoid; Protein Binding; Warfarin

1993
The genetic variant A of human alpha 1-acid glycoprotein limits the blood to brain transfer of drugs it binds.
    Life sciences, 1998, Volume: 62, Issue:14

    Topics: Animals; Blood-Brain Barrier; Chlorpromazine; Disopyramide; Genetic Variation; Humans; Imipramine; Male; Methadone; Mifepristone; Orosomucoid; Pharmacokinetics; Propranolol; Protein Binding; Rats; Rats, Wistar

1998
Antidepressant drugs inhibit glucocorticoid receptor-mediated gene transcription - a possible mechanism.
    British journal of pharmacology, 2000, Volume: 130, Issue:6

    Topics: Amantadine; Animals; Antidepressive Agents; Cell Line, Transformed; Chloramphenicol O-Acetyltransferase; Cocaine; Corticosterone; Cyclic AMP; Cyclic GMP; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Estrenes; Gene Expression Regulation; Imipramine; Lithium Chloride; Memantine; Mifepristone; Protein Kinase Inhibitors; Pyrrolidinones; Receptors, Glucocorticoid; Receptors, Steroid; Sulfonamides; Tamoxifen; Thionucleotides; Time Factors; Transcription, Genetic; Type C Phospholipases

2000
Stereoselective protein binding of tetrahydropalmatine enantiomers in human plasma, HSA, and AGP, but not in rat plasma.
    Chirality, 2010, Volume: 22, Issue:6

    Topics: Animals; Berberine Alkaloids; Binding, Competitive; Drug Interactions; Humans; Ibuprofen; Imipramine; Male; Mifepristone; Orosomucoid; Plasma; Protein Binding; Rats; Rats, Sprague-Dawley; Serum Albumin; Stereoisomerism; Substrate Specificity; Warfarin

2010
The selective glucocorticoid receptor antagonist CORT 108297 decreases neuroendocrine stress responses and immobility in the forced swim test.
    Hormones and behavior, 2014, Volume: 65, Issue:4

    Topics: Animals; Antidepressive Agents, Tricyclic; Aza Compounds; Behavior, Animal; Corticosterone; Heterocyclic Compounds, 4 or More Rings; Hormone Antagonists; Imipramine; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Stress, Psychological

2014