imipramine and metyrapone

imipramine has been researched along with metyrapone in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's1 (8.33)18.2507
2000's2 (16.67)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Grudin, R; Moldèus, P; Orrenius, S; Vadi, H1
Daniel, W; Netter, KJ1
Illing, HP; Kunke, S; Netter, KJ1
Borg, KO; Grundin, R; Moldéus, P; Orrenius, S; Skånberg, I; von Bahr, C1
Carson, SW; Fava, GA; Jusko, WJ; Molnar, G; Morphy, MA; Perini, GI1
Barber, HE; Kitteringham, NR; Petrie, JC1
Basta-Kaim, A; Budziszewska, B; Jaworska-Feil, L; Kubera, M; Lasoń, W; Rogóz, Z; Skuza, G1
Biala, G; Boguszewska-Czubara, A; Budzynska, B; Grot, K; Kruk-Slomka, M; Michalak, A; Pekala, K1

Reviews

1 review(s) available for imipramine and metyrapone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

11 other study(ies) available for imipramine and metyrapone

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Drug metabolism in isolated rat liver cells.
    Advances in experimental medicine and biology, 1975, Volume: 58, Issue:00

    Topics: Alprenolol; Animals; Biotransformation; Carbon Monoxide; Cells, Cultured; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Fasting; Glucose; Glucuronates; Imipramine; Lactates; Liver; Methods; Metyrapone; NADP; Oxidation-Reduction; Phenobarbital; Proadifen; Protein Binding; Rats; Rotenone; Spectrum Analysis; Temperature; Tritium

1975
Alteration of cytochrome P-450 by prolonged administration of imipramine and/or lithium to rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 342, Issue:2

    Topics: Animals; Carbamazepine; Cytochrome P-450 Enzyme System; Desipramine; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Hexobarbital; Imipramine; Isoenzymes; Lithium; Liver; Male; Metyrapone; Rats; Rats, Inbred Strains

1990
On the spectral intermediate at 440 nm formed during mixed function substrate oxidation.
    Biochemical pharmacology, 1974, Sep-15, Volume: 23, Issue:18

    Topics: Acetanilides; Aniline Compounds; Animals; Barbiturates; Cytochrome P-450 Enzyme System; Desipramine; Imipramine; In Vitro Techniques; Kinetics; Male; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Pentobarbital; Proadifen; Protein Binding; Rats; Spectrophotometry, Ultraviolet

1974
The possible role of cytochrome P-450 in the liver "first pass elimination" of a beta-receptor blocking drug.
    Acta pharmacologica et toxicologica, 1974, Volume: 35, Issue:3

    Topics: Administration, Oral; Alprenolol; Animals; Biological Availability; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Depression, Chemical; Imipramine; Injections, Intravenous; Liver; Male; Methods; Metyrapone; Microsomes, Liver; Perfusion; Phenobarbital; Proadifen; Rats; Spectrophotometry; Time Factors; Tritium

1974
The metyrapone test in affective disorders and schizophrenia II. Changes upon treatment.
    Journal of affective disorders, 1984, Volume: 7, Issue:3-4

    Topics: Adult; Aged; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Cortodoxone; Depressive Disorder; Female; Humans; Hydrocortisone; Imipramine; Lithium; Male; Metyrapone; Middle Aged; Psychotic Disorders; Psychotropic Drugs; Schizophrenia

1984
The effect of chlorpromazine, metyrapone, imipramine and SKF 525-A on the hepatic first pass elimination of propranolol in the pithed rat.
    British journal of pharmacology, 1982, Volume: 77, Issue:4

    Topics: Animals; Biotransformation; Chlorpromazine; Imipramine; Kinetics; Liver; Male; Metyrapone; Proadifen; Propranolol; Rats; Rats, Inbred Strains; Spinal Cord

1982
Effect of combined treatment with imipramine and metyrapone on the immobility time, the activity of hypothalamo-pituitary-adrenocortical axis and immunological parameters in the forced swimming test in the rat.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2005, Volume: 56, Issue:1

    Topics: Animals; Corticosterone; Depressive Disorder; Drug Therapy, Combination; Hypothalamo-Hypophyseal System; Imipramine; Immobilization; Male; Metyrapone; Pituitary-Adrenal System; Rats; Rats, Wistar; Swimming

2005
Behavioral and Biochemical Impact of Chronic Unpredictable Mild Stress on the Acquisition of Nicotine Conditioned Place Preference in Rats.
    Molecular neurobiology, 2018, Volume: 55, Issue:4

    Topics: Animals; Behavior, Animal; Choice Behavior; Chronic Disease; Conditioning, Classical; Imipramine; Male; Metyrapone; Motor Activity; Nicotine; Oxidative Stress; Rats, Wistar; Stress, Psychological; Tobacco Use Disorder

2018