imipramine has been researched along with methyldopa in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (53.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (14.29) | 29.6817 |
| 2010's | 9 (32.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bhattacharya, SK; Das, PK; Mukhopadhyay, SN; Reddy, PK | 1 |
| van Spanning, HW; van Zwieten, PA | 1 |
| Kilbinger, H; Racké, K; Schwörer, H | 1 |
| Modigh, K | 1 |
| Duvoisin, RC; Yahr, MD | 1 |
| Turkington, RW | 1 |
| Presthus, J | 1 |
| Fossati, C | 1 |
| Haefely, W | 1 |
| Kale, AK; Satoskar, RS | 1 |
| Kariya, T; Kobayashi, K; Kobayashi, T; Nagao, Y; Takahashi, R; Takamizawa, M; Toru, M; Tsuchiya, K | 1 |
| Bhargava, KP; Gupta, ML | 1 |
| Applebaum, SM | 1 |
| BAN, TA; DONALD, MW; SAINTJEAN, A | 1 |
6 review(s) available for imipramine and methyldopa
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drug therapy of parkinsonism.
Topics: Amantadine; Amitriptyline; Amphetamine; Antiparkinson Agents; Dihydroxyphenylalanine; Drug Antagonism; Drug Synergism; Humans; Imipramine; Methyldopa; Monoamine Oxidase Inhibitors; Parasympatholytics; Parkinson Disease; Phenothiazines | 1972 |
[Other trials with drug therapy in parkinsonism].
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Dihydroxyphenylalanine; Disulfiram; Drug Evaluation; Drug Therapy, Combination; Humans; Imipramine; Methyldopa; Monoamine Oxidase Inhibitors; Parkinson Disease; Picolinic Acids; Rats; Serine; Time Factors; Tryptophan; Tyrosine | 1973 |
[Liver damage due to drugs. I].
Topics: Arsenicals; Chemical and Drug Induced Liver Injury; Chloramphenicol; Cholestasis; Coumarins; Drug-Related Side Effects and Adverse Reactions; Erythromycin; Halothane; Humans; Imipramine; Liver; Methotrexate; Methyldopa; Nicotinic Acids; Oxacillin; Phenylbutazone; Testosterone; Tetracycline | 1974 |
[Drugs with effect on the adrenergic nerve fiber].
Topics: Aminocaproates; Amitriptyline; Amphetamine; Bretylium Compounds; Chlorpromazine; Disulfiram; Dopamine; Ephedrine; Guanethidine; Humans; Imipramine; Mental Disorders; Metaraminol; Methyldopa; Methyltyrosines; Monoamine Oxidase Inhibitors; Neurons; Norepinephrine; Octopamine; Prenylamine; Reserpine; Sympathetic Nervous System; Sympathomimetics; Tetrabenazine; Tyramine; Vascular Diseases | 1968 |
Pharmacologic agents in micturitional disorders.
Topics: Baclofen; Bethanechol Compounds; Dantrolene; Dicyclomine; Ephedrine; Flavoxate; Guanethidine; Humans; Imipramine; Mandelic Acids; Methyldopa; Neostigmine; Phenoxybenzamine; Phentolamine; Phenylephrine; Phenylpropanolamine; Propantheline; Propranolol; Quaternary Ammonium Compounds; Urinary Bladder; Urination Disorders | 1980 |
1 trial(s) available for imipramine and methyldopa
| Article | Year |
|---|---|
Prolactin secretion in patients treated with various drugs: phenothiazines, tricyclic antidepressants, reserpine, and methyldopa.
Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Clinical Trials as Topic; Fluphenazine; Humans; Hypertension; Imipramine; Injections, Intramuscular; Methyldopa; Phenothiazines; Prolactin; Promazine; Reserpine; Stimulation, Chemical; Time Factors; Tranquilizing Agents | 1972 |
21 other study(ies) available for imipramine and methyldopa
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Role of brain monoamines in the anticonvulsant effect of imipramine in albino rats.
Topics: Animals; Anticonvulsants; Apomorphine; Catecholamines; Ditiocarb; Dopamine; Drug Interactions; Electroshock; Female; Fenclonine; Haloperidol; Hydroxydopamines; Imipramine; Male; Methyldopa; Methyltyrosines; Methysergide; Norepinephrine; Phenoxybenzamine; Propranolol; Rats; Reserpine; Seizures; Serotonin | 1976 |
The interaction between alpha-methyl-dopa and tricyclic antidepressants.
Topics: Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Cats; Desipramine; Drug Interactions; Female; Imipramine; Male; Methyldopa | 1975 |
Spontaneous release of endogenous 5-hydroxytryptamine and 5-hydroxyindoleacetic acid from the isolated vascularly perfused ileum of the guinea-pig.
Topics: Animals; Calcium; Guinea Pigs; Hydroxyindoleacetic Acid; Ileum; Imipramine; In Vitro Techniques; Male; Methyldopa; Myenteric Plexus; Pargyline; Perfusion; Portal Vein; Serotonin; Tetrodotoxin; Tryptophan | 1987 |
Functional aspects of 5-hydroxytryptamine turnover in the central nervous system.
Topics: 5-Hydroxytryptophan; Acetamides; Animals; Antidepressive Agents; Brain; Catecholamines; Depression, Chemical; Dihydroxyphenylalanine; Fenclonine; Humans; Hydrazines; Imipramine; Male; Methyldopa; Motor Activity; Nialamide; Receptors, Drug; Reserpine; Serotonin; Stimulation, Chemical; Stress, Psychological; Tryptophan; Tyrosine | 1974 |
[Interaction between antidepressive and antihypertensive drugs].
Topics: Antidepressive Agents; Antihypertensive Agents; Drug Antagonism; Guanethidine; Imipramine; Methyldopa | 1970 |
Modification of the central hypotensive effect of alpha-methyldopa by reserpine, imipramine and tranylcypromine.
Topics: Animals; Blood Pressure; Cats; Depression, Chemical; Female; Imipramine; Injections, Intra-Arterial; Injections, Intravenous; Male; Methyldopa; Reserpine; Time Factors; Tranylcypromine | 1970 |
Catecholamine metabolism of manic-depressive illness.
Topics: Antidepressive Agents; Bipolar Disorder; Calcium; Catecholamines; Creatinine; Disulfiram; Dopamine; Epinephrine; Humans; Hydroxyindoleacetic Acid; Imipramine; Male; Methyldopa; Middle Aged; Norepinephrine; Phenylacetates; Psychiatric Status Rating Scales; Vanilmandelic Acid | 1968 |
A study of central adrenergic mechanisms in the regulation of the oestrous cycle of albino mice.
Topics: Animals; Catecholamines; Estrus; Female; Imipramine; Methyldopa; Methyltyrosines; Mice; Monoamine Oxidase Inhibitors; Pregnancy; Sensory Receptor Cells; Sympathetic Nervous System; Tyrosine | 1966 |
[THE PSYCHOPHYSIOLOGICAL EFFECTS OF METHYLDOPA].
Topics: Blood Pressure; Blood Pressure Determination; Depression; Depressive Disorder; Dihydroxyphenylalanine; Hypertension; Imipramine; Methyldopa; Psychopharmacology; Schizophrenia | 1963 |