imipramine has been researched along with methimazole in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Biassoni, R; Vaccari, A | 1 |
| Hale, SE; Masters, BS; Nordin, DJ; Williams, DE; Ziegler, DM | 1 |
| Buxeraud, J; Comby, F; Raby, C; Rousseau, A | 1 |
| Benoit, E; Buronfosse, T; Lattard, V; Lilaz-Michel, C; Longin-Sauvageon, C | 1 |
| Lawton, MP; Overby, LH; Philpot, RM; Wyatt, MK | 1 |
| Adali, O; Carver, GC; Philpot, RM | 1 |
1 review(s) available for imipramine and methimazole
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
12 other study(ies) available for imipramine and methimazole
| Article | Year |
|---|---|
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Selective effects of thiol reagents on the binding sites for imipramine and neurotransmitter amines in the rat brain.
Topics: Animals; Brain; Carrier Proteins; Dithionitrobenzoic Acid; Dithiothreitol; Ethylmaleimide; Hydroxymercuribenzoates; Imipramine; Male; Mercaptoethanol; Methimazole; Propylthiouracil; Rats; Receptors, Dopamine; Receptors, Drug; Receptors, Neurotransmitter; Serotonin; Spiperone; Sulfhydryl Reagents | 1985 |
Rabbit lung flavin-containing monooxygenase is immunochemically and catalytically distinct from the liver enzyme.
Topics: Aniline Compounds; Animals; Chlorpromazine; Cross Reactions; Cysteamine; Female; Guinea Pigs; Imipramine; Immunodiffusion; Liver; Lung; Methimazole; Oxygenases; Pregnancy; Rabbits; Substrate Specificity; Swine | 1984 |
Spectroscopic analysis of charge transfer complex formation and peroxidase inhibition with tricyclic antidepressant drugs: potential anti-thyroid action.
Topics: Antidepressive Agents, Tricyclic; Antithyroid Agents; Clomipramine; Desipramine; Horseradish Peroxidase; Imipramine; Iodine; Kinetics; Methimazole; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1996 |
Expression of two different FMOs in sheep liver.
Topics: Amino Acid Sequence; Animals; Binding Sites; Female; Gene Expression; Imipramine; Kinetics; Methimazole; Methionine; Methylamines; Microsomes, Liver; Molecular Sequence Data; Oxygenases; Sheep | 1998 |
Identification of amino acid residues associated with modulation of flavin-containing monooxygenase (FMO) activity by imipramine: structure/function studies with FMO1 from pig and rabbit.
Topics: Amino Acid Substitution; Amino Acids; Animals; Catalysis; Enzyme Activation; Genetic Vectors; Imipramine; Methimazole; Mutagenesis, Site-Directed; Oxygenases; Rabbits; Recombinant Fusion Proteins; Structure-Activity Relationship; Swine | 1998 |
Modulation of human flavin-containing monooxygenase 3 activity by tricyclic antidepressants and other agents: importance of residue 428.
Topics: Amines; Amino Acid Substitution; Antidepressive Agents, Tricyclic; Catalysis; Chlorpromazine; Enzyme Activation; Humans; Imipramine; Lysine; Magnesium Chloride; Mercuric Chloride; Methimazole; Mutagenesis, Site-Directed; Oxygenases; Threonine | 1998 |