imipramine and meperidine

imipramine has been researched along with meperidine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199018 (58.06)18.7374
1990's1 (3.23)18.2507
2000's7 (22.58)29.6817
2010's5 (16.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Nagashima, R; Nishikawa, T; Tobita, M1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Sen, S; Sinha, N1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bissada, NK; Finkbeiner, AE; Welch, LT1
Baust, W; Jörg, J; Wortmann, R; Zimmermann, A1
Gastmeier, K; Hass, M; Kuteifan, K; Schott, H1
Bromm, B; Meier, W; Scharein, E2
Wood, M1
Gong, SN; Rogers, KJ2
Gong, NC; Rogers, KJ1
Ahtee, L; Jounela, AJ; Saarnivaara, L; Simola, I1
Clark, B1
Clark, B; Thompson, JW; Widdrington, G1
Baum, T; Eckfeld, DK; Rowles, G; Shropshire, AT; Varner, LL1
Carlsson, A; Fuxe, K; Meek, JL1
Blumberg, AG; Heaton, AM1
JACOBSEN, P1
ENGELMAN, K; HORWITZ, D; LOVENBERG, W; SJOERDSMA, A1
PARE, CM1
LOB, H; POINSO, Y; SOULAYROL, R1

Reviews

4 review(s) available for imipramine and meperidine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Uropharmacology: X. Central nervous system stimulants and depressants.
    Urology, 1979, Volume: 13, Issue:4

    Topics: Amphetamines; Anesthetics; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Baclofen; Benzodiazepines; Central Nervous System Agents; Chloral Hydrate; Humans; Imipramine; Levodopa; Meperidine; Meprobamate; Morphine; Nortriptyline; Paraldehyde; Phenothiazines; Phenytoin; Picrotoxin; Reserpine; Strychnine; Urinary Tract

1979
Plasma drug binding: implications for anesthesiologists.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:7

    Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Cardiac Surgical Procedures; Chlorpromazine; Dipyridamole; Disopyramide; Etidocaine; Female; Fentanyl; Half-Life; Humans; Imipramine; Kidney Diseases; Lidocaine; Liver; Mathematics; Meperidine; Methadone; Myocardial Infarction; Orosomucoid; Prazosin; Pregnancy; Propranolol; Protein Binding; Quinidine; Serum Albumin; Sex Factors

1986

Trials

2 trial(s) available for imipramine and meperidine

ArticleYear
Pre-stimulus/post-stimulus relations in EEG spectra and their modulations by an opioid and an antidepressant.
    Electroencephalography and clinical neurophysiology, 1989, Volume: 73, Issue:3

    Topics: Adult; Delta Rhythm; Double-Blind Method; Electroencephalography; Evoked Potentials, Somatosensory; Humans; Imipramine; Male; Meperidine; Pain; Theta Rhythm

1989
Imipramine reduces experimental pain.
    Pain, 1986, Volume: 25, Issue:2

    Topics: Adult; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Dibenzoxazepines; Double-Blind Method; Electroencephalography; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Humans; Imipramine; Male; Meperidine; Pain; Placebos; Sensory Thresholds

1986

Other Studies

25 other study(ies) available for imipramine and meperidine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
[Studies on the effect of drugs on somatosensory cortical evoked potentials (author's transl)].
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:2

    Topics: Chlorpromazine; Diazepam; Dipyrone; Evoked Potentials; Humans; Imipramine; Meperidine; Methamphetamine; Phenobarbital; Somatosensory Cortex

1977
[Pain therapy for urologic cancer patients at the Potsdam district hospital--initial results].
    Zeitschrift fur Urologie und Nephrologie, 1990, Volume: 83, Issue:10

    Topics: Aged; Amitriptyline; Analgesics; Analgesics, Opioid; Aspirin; Carbamazepine; Codeine; Dipyrone; Drug Therapy, Combination; Haloperidol; Humans; Imipramine; Indomethacin; Meperidine; Morphine; Pain; Pain Measurement; Prospective Studies; Urologic Neoplasms

1990
Role of brain monoamines in the fatal hyperthermia induced by pethidine or imipramine in rabbits pretreated with pargyline.
    British journal of pharmacology, 1971, Volume: 42, Issue:4

    Topics: Animals; Brain; Brain Chemistry; Catecholamines; Fenclonine; Fever; Imipramine; Injections, Intravenous; Meperidine; Monoamine Oxidase Inhibitors; Pargyline; Rabbits; Serotonin

1971
Role of brain monoamines in the fatal hyperthermia induced by pethidine or imipramine in rabbits pretreated with a monoamine oxidase inhibitor.
    British journal of pharmacology, 1973, Volume: 48, Issue:1

    Topics: Amines; Animals; Body Temperature; Brain Chemistry; Brain Stem; Dopamine; Fenclonine; Hypernatremia; Imipramine; Male; Meperidine; Methyltyrosines; Monoamine Oxidase Inhibitors; Norepinephrine; Pargyline; Rabbits; Reserpine; Serotonin; Time Factors

1973
Mechanism of hyperthermia in the interaction between pethidine or imipramine and monoamine oxidase inhibitors.
    The Medical journal of Malaysia, 1973, Volume: 27, Issue:4

    Topics: Animals; Body Temperature Regulation; Drug Interactions; Fever; Humans; Imipramine; Male; Meperidine; Monoamine Oxidase Inhibitors; Pargyline; Rabbits

1973
Interactions of some analgesics and antidepressants with phenelzine or reserpine in the mouse.
    Pharmacology, 1974, Volume: 12, Issue:1

    Topics: Alphaprodine; Analgesics; Animals; Antidepressive Agents; Body Temperature; Drug Interactions; Fenclonine; Hypothermia; Imipramine; Isonipecotic Acids; Lethal Dose 50; Male; Meperidine; Methadone; Mice; Pentazocine; Phenelzine; Reserpine; Time Factors

1974
The in vitro inhibition of the N-demethylation of pethidine by phenelzine (Phenethylhydrazine).
    Biochemical pharmacology, 1967, Volume: 16, Issue:12

    Topics: Alkaline Phosphatase; Animals; Cytochromes; Electron Transport; Esterases; Imipramine; Kinetics; Liver; Male; Meperidine; Microsomes; NADP; Oxidoreductases; Phenelzine; Rats

1967
Analysis of the inhibition of pethidine N-demethylation by monoamine oxidase inhibitors and some other drugs with special reference to drug interactions in man.
    British journal of pharmacology, 1972, Volume: 44, Issue:1

    Topics: Amphetamine; Animals; Chlorpromazine; Desipramine; Drug Interactions; Histamine; Hydrazines; Hydrocortisone; Imipramine; Iproniazid; Male; Meperidine; Methylation; Microsomes, Liver; Monoamine Oxidase Inhibitors; Nialamide; Opipramol; Phenothiazines; Phenylhydrazines; Prednisolone; Proadifen; Promazine; Rats; Transferases

1972
Observations on models used for the evaluation of antiarrhythmic drugs.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 193, Issue:1

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atropine; Benzazepines; Bretylium Compounds; Chlorpheniramine; Diazepam; Disease Models, Animal; Dogs; Drug Antagonism; Guinea Pigs; Imipramine; Ketones; Lidocaine; Male; Meperidine; Mephentermine; Ouabain; Phentolamine; Phenytoin; Procainamide; Promazine; Promethazine; Propranolol; Quinidine

1971
Blockade of p-chloromethamphetamine induced 5-hydroxytryptamine depletion by chlorimipramine, chlorpheniramine and meperidine.
    Biochemical pharmacology, 1971, Volume: 20, Issue:3

    Topics: Amphetamine; Animals; Chlorine; Chlorpheniramine; Dibenzazepines; Imipramine; Male; Meperidine; Rats; Rats, Inbred Strains; Serotonin; Tyramine

1971
Thin-layer chromatographic detection of barbiturates, narcotics, and amphetamines in urine of patients receiving psychotropic drugs.
    Journal of chromatography, 1969, May-20, Volume: 41, Issue:3

    Topics: Amphetamine; Barbiturates; Chlorpromazine; Chromatography, Thin Layer; Cocaine; Codeine; Humans; Imipramine; Ion Exchange Resins; Meperidine; Methadone; Morphine; Narcotics; Quinine; Thioridazine; Trifluoperazine

1969
Cause of death in narcotic intoxication in recent years.
    Danish medical bulletin, 1963, Volume: 10

    Topics: Cause of Death; Chlorprothixene; Heart Diseases; Humans; Imipramine; Kidney Diseases; Lung Diseases; Meperidine; Morphine; Narcotics; Shock

1963
MONOAMINE OXIDASE INHIBITORS, TYRAMINE, AND CHESSE.
    JAMA, 1964, Jun-29, Volume: 188

    Topics: Cheese; Food Analysis; Hypertension; Imipramine; Meperidine; Monoamine Oxidase Inhibitors; Nialamide; Pharmacology; Phenelzine; Phentolamine; Toxicology; Tranylcypromine; Tyramine

1964
TOXICITY OF PSYCHOTROPIC DRUGS. SIDE-EFFECTS AND TOXIC EFFECTS OF ANTIDEPRESSANTS.
    Proceedings of the Royal Society of Medicine, 1964, Volume: 57

    Topics: Amitriptyline; Antidepressive Agents; Convulsive Therapy; Electroconvulsive Therapy; Headache; Imipramine; Meperidine; Monoamine Oxidase Inhibitors; Psychopharmacology; Psychotropic Drugs; Toxicology; Tryptophan

1964
[INCIDENTS DUE TO DRUG INTERFERENCE WITH MONOAMINE OXIDASE INHIBITORS].
    Revue de neuropsychiatrie infantile et d'hygiene mentale de l'enfance, 1964, Volume: 12

    Topics: Amphetamine; Amphetamines; Coma; Hypotension; Imipramine; Meperidine; Monoamine Oxidase Inhibitors; Nikethamide; Phenylephrine; Shock; Shock, Septic; Toxicology

1964