Compounds > imipramine

imipramine and mecamylamine

imipramine has been researched along with mecamylamine in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (36.36)	18.7374
1990's	1 (9.09)	18.2507
2000's	2 (18.18)	29.6817
2010's	4 (36.36)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Fellhauer, M	1
Bell, S; Jhamandas, K; Sutak, M	1
Vaillant, GE	1
Fekete, M	1
Ceña, V; García, AG; Montiel, C; Sánchez-García, P	1
Brodkin, JD; Ferguson, SM; Lloyd, GK; Menzaghi, F	1
Arias, HR; Feuerbach, D; Jozwiak, K; Maciejewski, R; Sullivan, CJ; Targowska-Duda, KM	1
Arias, HR; Feuerbach, D; Jozwiak, K; Moaddel, R; Rosenberg, A; Targowska-Duda, KM; Wainer, IW	1

Reviews

1 review(s) available for imipramine and mecamylamine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

10 other study(ies) available for imipramine and mecamylamine

Article	Year
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
[Drug treatment of nicotine dependence]. Medizinische Monatsschrift fur Pharmazeuten, 1990, Volume: 13, Issue:6 Topics: Clonidine; Doxepin; Humans; Imipramine; Mecamylamine; Nicotine; Smoking; Substance Withdrawal Syndrome	1990
Modification of precipitated morphine withdrawal syndrome by drugs affecting cholinergic mechanisms. European journal of pharmacology, 1973, Volume: 24, Issue:3 Topics: Animals; Atropine; Autonomic Nervous System; Diphenhydramine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Imipramine; Mecamylamine; Morphine; Morphine Dependence; Naloxone; Neurotransmitter Agents; Physostigmine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Substance Withdrawal Syndrome; Synaptic Transmission; Tolazoline	1973
A comparison of antagonists of physostigmine-induced suppression of behavior. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 157, Issue:3 Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Chlorpromazine; Columbidae; Diphenhydramine; Haplorhini; Imipramine; Male; Mecamylamine; Muscles; Parasympatholytics; Physostigmine; Scopolamine; Trihexyphenidyl	1967
A possible role of cholinergic effects in the noradrenaline potentiating action of imipramine. Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1966, Volume: 14, Issue:3 Topics: Animals; Arrhythmias, Cardiac; Bradycardia; Cats; Dogs; Electrocardiography; Female; Hexamethonium Compounds; Imipramine; Male; Mecamylamine; Neostigmine; Norepinephrine; Parasympathomimetics; Tachycardia	1966
Uptake of [3H]-nicotine and [3H]-noradrenaline by cultured chromaffin cells. British journal of pharmacology, 1984, Volume: 81, Issue:1 Topics: Adrenal Medulla; Animals; Cattle; Cell Membrane; Cells, Cultured; Chromaffin System; Cocaine; Imipramine; Mecamylamine; Nicotine; Norepinephrine; Tetracaine	1984
Antidepressant-like effects of the subtype-selective nicotinic acetylcholine receptor agonist, SIB-1508Y, in the learned helplessness rat model of depression. Psychopharmacology, 2000, Volume: 152, Issue:3 Topics: Animals; Antidepressive Agents; Avoidance Learning; Depression; Dose-Response Relationship, Drug; Imipramine; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Pyridines; Pyrrolidines; Rats; Rats, Sprague-Dawley	2000
Different interaction between tricyclic antidepressants and mecamylamine with the human alpha3beta4 nicotinic acetylcholine receptor ion channel. Neurochemistry international, 2010, Volume: 56, Issue:4 Topics: Antidepressive Agents, Tricyclic; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cell Membrane; Cells, Cultured; Humans; Imipramine; Ion Channels; Mecamylamine; Models, Molecular; Nicotinic Agonists; Nicotinic Antagonists; Protein Binding; Protein Conformation; Pyridines; Receptors, Nicotinic	2010
Tricyclic antidepressants and mecamylamine bind to different sites in the human alpha4beta2 nicotinic receptor ion channel. The international journal of biochemistry & cell biology, 2010, Volume: 42, Issue:6 Topics: Antidepressive Agents, Tricyclic; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Calcium Signaling; Cell Line; Humans; Imipramine; Ion Channels; Mecamylamine; Nicotinic Antagonists; Protein Binding; Protein Conformation; Pyridines; Receptors, Nicotinic	2010