imipramine and maprotiline

imipramine has been researched along with maprotiline in 118 studies

Research

Studies (118)

Timeframe	Studies, this research(%)	All Research%
pre-1990	66 (55.93)	18.7374
1990's	16 (13.56)	18.2507
2000's	19 (16.10)	29.6817
2010's	14 (11.86)	24.3611
2020's	3 (2.54)	2.80

Authors

Authors	Studies
Medina-Hernández, MJ; Quiñones-Torrelo, C; Sagrado, S; Villanueva-Camañas, RM	1
Topliss, JG; Yoshida, F	1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M	1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Ikeda, K; Kobayashi, T; Washiyama, K	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahman, M; Holmén, AG; Wan, H	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Gozalbes, R; Pineda-Lucena, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Cardoso, FC; Duggan, PJ; Kuiper, MJ; Lewis, RJ; Schmit, M; Tuck, KL	1
Delini-Stula, A; Radeke, E; Vassout, A	1
Feighner, JP; Logue, JN; Sachais, BA	1
Baumann, PA; Maître, L	1
Anlezark, G; Meldrum, B; Trimble, M	1
Hole, G; Pühringer, W; Wirz-Justice, A	1
Dürst, T; Glatt, A; Klebs, K; Koella, WP	1
Gupta, R; Molnar, G; Wallace, J	1
Delini-Stula, A; Vassout, A	2
Huey, LY; Janowsky, DS; Risch, SC	1
Bolaños, J; Morillas, MG; Mundo Salvador, A; Puche, E	1
Hughes, IE; Radman, S	1
Benesová, O; Horák, J; Jelínek, R; Soucek, K	1
Bolanos, J; García Morillas, M; Mundo Salvador, A; Puche Cañas, E	1
Hughes, IE; Radwan, S	1
Gent, M; Nelson, HL; Saxena, B; Singh, AN	1
Ban, TA; Lehmann, HE; Orbach, L; Pecknold, JC	1
Claeys, M; Maenhaut, W; Markey, SP	1
Anlezark, G; Meldrum, BS; Trimble, MR	1
Mundo Salvador, A; Puche Cañas, E	2
Holt, NF; Kessell, A	1
Bothwell, S; Lieb, J; Prusoff, B; Weissman, MM	1
Chen, PO; Endo, T; Matsuda, H; Nishimori, T; Sato, K; Shibuya, T	1
Benesová, O	2
Fujiwara, M; Ibii, N; Inoue, K; Kataoka, Y; Ueki, S	1
Biamino, G; Neye, G; Neye, J; Nöring, J	1
Maj, J; Rogóz, Z; Skuza, G; Sowińska, H	1
Delini-Stula, A; Herrmann, WM; Schärer, E; Wendt, G	1
Kawasaki, H; Nuki, C; Takasaki, K; Tasaki, H; Urabe, M; Yamamoto, R	1
Goromaru, T; Hashimoto, K	1
Davies, SL; Hale, AS; Horton, RW; Katona, CL; Kelly, JS; Kerry, SM; Paykel, ES; Theodorou, AE	1
Bigajska, K; Maj, J; Papp, M; Skuza, G; Zazula, M	1
Bijak, M	1
Ichikawa, T; Koizumi, J; Suzuki, T; Terashima, Y	1
Barbaccia, ML; Costa, E; Szekely, AM	1
Arita, M; Izumi, F; Takara, H; Wada, A	1
Beliaev, BS; Brusov, OS; Factor, MI; Katasonov, AB; Lideman, RR; Zlobina, GP	1
Benkelfat, C; Galzin, AM; Langer, SZ; Loo, H; Pimoule, C; Poirier, MF; Schoemaker, H; Sechter, D; Segonzac, A; Zarifian, E	1
Domínguez-Gil, A; Fernández de Gatta, MM; García, MJ; Gutierrez, JR; Tamayo, M	1
Baumann, P; Cuendet, C; Eap, CB	1
Hasegawa, J; Hirai, S; Kinugawa, T; Kotake, H; Mashiba, H; Matsuoka, S	1
Faltus, F; Filip, V; Karen, P; Kolomazník, M; Korínková, V; Libiger, J; Molcan, J; Zapletálek, M; Zizka, V	1
Lydiard, RB	1
Hauser, K; Häusler, A; Meeker, JB	1
Carlini, EL; Del-Porto, JA; Zwicker, AP	1
Clifford, DB; Hicks, FG; Rutherford, JL; Zorumski, CF	1
Kameyama, T; Nagasaka, M; Yamada, K	1
Kawasaki, H; Ueki, S; Watanabe, S	1
Arató, M; Grof, P; Rihmer, Z; Szádóczky, E	1
Archer, T; Minor, BG; Ross, SB	1
Kane, JM; Lieberman, J	1
Gold, MS; Lydiard, RB; Pottash, AL	1
Bradford, D; Krijzer, F; Snelder, M	1
Itoh, M; Nakao, H; Notomi, A; Yufu, N	1
Feinberg, M; Genero, N; Greden, JF; Levine, S; Price, HL	1
Stapert, WG	1
Forette, F; Gomeni, R; Henry, JF; Hervy, MP; Hrdina, PD; Morselli, PL; Rovei, V	1
Braithwaite, RA	1
van der Velde, CD	1
Logue, JN; Sachais, BA	1
Rifkin, A	1
Molcan, J; Nábĕlek, L; Novotný, V	1
Faltus, F	1
Böning, J	1
Cole, JO; Orsulak, PJ; Rosenbaum, AH; Schatzberg, AF; Schildkraut, JJ	1
Coppen, A; Peet, M	1
García Morillas, M; Mundo, A; Puche, E; Saucedo, R	1
Cole, JO; Grab, EL; Maruta, T; Orsulak, PJ; Rosenbaum, AH; Schatzberg, AF; Schildkraut, JJ	1
Angst, J; Delini-Stula, A; Mikkelsen, H	1
Miranda, HF; Pinardi, G; Sierralta, F	1
Mendez, M; Miranda, HF; Pinardi, G; Sierralta, F	1
Abdel el-Latif, HA; Ammon, HP; el-Dakhakhny, M	1
Baba, A; Hori, T; Kurita, H; Piletz, JE; Sasaki, M; Shiraishi, H; Suzuki, T	1
Bourin, M; Redrobe, JP	1
Dziedzicka-Wasylewska, M; Klimek, V; Maj, J; Rogoz, R	1
Blomgren, B; Dahlin, KL; Lâstbom, L; Ryrfeldt, A	1
Aymard, G; Diquet, B; Livi, P; Pham, YT	1
Casis, O; Sánchez-Chapula, JA	1
Egashira, T; Takayama, F; Yamanaka, Y	1
Obata, T; Yamanaka, Y	1
Inoue, T; Koyama, T	1
Casis, O; Gallego, M; Sánchez-Chapula, JA	1
Hashimoto, S; Hattori, T; Kawasaki, K; Kitamura, Y; Miki, N; Mochizuki, D; Otsuka, Y; Tsujita, R; Yamada, S	1
Feltenstein, MW; Sufka, KJ	1
Brenneman, D; Crooke, J; Malatynska, E; Pinhasov, A; Rosenthal, D	1
Ikenouchi-Sugita, A; Nakamura, J; Yoshimura, R	1
Acevedo, EO; Huang, CJ; Sufka, KJ; Warnick, JE	1
Belzung, C; Surget, A; Yalcin, I	1
Aboukhatwa, MA; Undieh, AS	1
Cavender, HM; Cooke, JD; Grover, LM; Lima, HK	1
Giles, R; Girard, MFC; Hopfgartner, G; Knight, P	1
Yamini, Y; Zamani, R	1

Reviews

7 review(s) available for imipramine and maprotiline

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Neurobiochemical aspects of maprotiline (Ludiomil) action. The Journal of international medical research, 1979, Volume: 7, Issue:5 Topics: Animals; Anthracenes; Brain; Cats; Depression, Chemical; Dopamine; Heart; Humans; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Maprotiline; Norepinephrine; Rats; Serotonin; Synaptosomes; Tryptophan	1979
The efficacy of amoxapine, maprotiline, and trazodone in comparison to imipramine and amitriptyline: a review of the literature. Psychopharmacology bulletin, 1984,Spring, Volume: 20, Issue:2 Topics: Amitriptyline; Amoxapine; Anthracenes; Clinical Trials as Topic; Depression; Dibenzoxazepines; Humans; Imipramine; Maprotiline; Piperazines; Time Factors; Trazodone	1984
Plasma-protein binding of tricyclic antidepressants. Postgraduate medical journal, 1980, Volume: 56 Suppl 1 Topics: Aged; Antidepressive Agents, Tricyclic; Binding Sites; Blood Proteins; Clomipramine; Humans; Imipramine; Maprotiline; Protein Binding	1980
Therapeutic efficacy of antidepressants in agitated anxious depression--a meta-analysis of moclobemide studies. Journal of affective disorders, 1995, Oct-09, Volume: 35, Issue:1-2 Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Anxiety Disorders; Benzamides; Clinical Trials as Topic; Depressive Disorder; Female; Humans; Imipramine; Male; Maprotiline; Mianserin; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Personality Assessment; Psychomotor Agitation; Treatment Outcome	1995
[Tricyclic antidepressant, tetracyclic antidepressant]. Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59, Issue:8 Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Humans; Imipramine; Maprotiline; Selective Serotonin Reuptake Inhibitors	2001
[Review of pharmacological efficacies and side effects of antidepressants]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Volume: 65, Issue:9 Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Fluvoxamine; Humans; Imipramine; Maprotiline; Paroxetine; Sulpiride; Trazodone	2007

Trials

12 trial(s) available for imipramine and maprotiline

Article	Year
Comparisons of maprotiline with imipramine in severe depression: a multicenter controlled trial. Journal of clinical pharmacology, 1979, Volume: 19, Issue:1 Topics: Adolescent; Adult; Aged; Anthracenes; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Psychiatric Status Rating Scales	1979
Maprotiline (Ludiomil, Ciba 34,276-BA) and imipramine in depressed outpatients: a double-blind clinical study. Current therapeutic research, clinical and experimental, 1976, Volume: 19, Issue:4 Topics: Adult; Ambulatory Care; Analysis of Variance; Anthracenes; Antidepressive Agents; Anxiety; Clinical Trials as Topic; Depression; Drug Evaluation; Electroencephalography; Female; Hostility; Humans; Imipramine; Male; Maprotiline; Middle Aged; Psychiatric Status Rating Scales; Psychophysiologic Disorders; Sleep Wake Disorders	1976
A double-blind comparative clinical trial with maprotiline (Ludiomil) and imipramine in newly-admitted depressed patients. Current therapeutic research, clinical and experimental, 1976, Volume: 19, Issue:4 Topics: Adult; Aged; Ambulatory Care; Analysis of Variance; Anthracenes; Antidepressive Agents; Clinical Trials as Topic; Depression; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Psychiatric Status Rating Scales; Self-Assessment	1976
A controlled study of a tetracyclic antidepressant--maprotiline (Ludiomil). The Medical journal of Australia, 1975, Jun-21, Volume: 1, Issue:25 Topics: Adjustment Disorders; Adult; Anthracenes; Bipolar Disorder; Body Weight; Clinical Trials as Topic; Depression; Drive; Female; Humans; Imipramine; Maprotiline; Psychiatric Status Rating Scales; Time Factors	1975
A double-blind trial of maprotiline (Ludiomil) and amitriptyline in depressed outpatients. Acta psychiatrica Scandinavica, 1975, Volume: 52, Issue:4 Topics: Adult; Aged; Amitriptyline; Analysis of Variance; Anthracenes; Clinical Trials as Topic; Depression; Drug Evaluation; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Regression Analysis	1975
Pharmaco-EEG profile of levoprotiline: second example to discuss the predictive value of pharmaco-electroencephalography in early human pharmacological evaluations of psychoactive drugs. Pharmacopsychiatry, 1991, Volume: 24, Issue:6 Topics: Adult; Antidepressive Agents; Double-Blind Method; Electroencephalography; Humans; Imipramine; Male; Maprotiline	1991
[Comparison of nomifensine, maprotiline and imipramine in a double-blind study of patients with endogenous depression]. Ceskoslovenska psychiatrie, 1986, Volume: 82, Issue:2 Topics: Adult; Anthracenes; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nomifensine	1986
Lack of agreement between the salivary flow and finger-sweat print methods for the determination of the anticholinergic effects of antidepressant drugs. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1985, Volume: 18, Issue:2 Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Dermatoglyphics; Double-Blind Method; Female; Humans; Imipramine; Male; Maprotiline; Mianserin; Parasympathetic Nervous System; Salivation; Sweating	1985
The efficacy of amoxapine, maprotiline, and trazodone in comparison to imipramine and amitriptyline: a review of the literature. Psychopharmacology bulletin, 1984,Spring, Volume: 20, Issue:2 Topics: Amitriptyline; Amoxapine; Anthracenes; Clinical Trials as Topic; Depression; Dibenzoxazepines; Humans; Imipramine; Maprotiline; Piperazines; Time Factors; Trazodone	1984
Speed of onset of action of the newer antidepressants. Psychopharmacology bulletin, 1984,Spring, Volume: 20, Issue:2 Topics: Amitriptyline; Amoxapine; Antidepressive Agents; Clinical Trials as Topic; Depression; Depressive Disorder; Double-Blind Method; Humans; Imipramine; Maprotiline; Time Factors; Trazodone	1984
Maprotiline versus imipramine and placebo in neurotic depression. The Journal of clinical psychiatry, 1981, Volume: 42, Issue:4 Topics: Adolescent; Adult; Aged; Anthracenes; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Humans; Imipramine; Maprotiline; Middle Aged; Psychiatric Status Rating Scales	1981
Factors which affect antidepressant drug responses in a multicenter controlled trial [proceedings]. Psychopharmacology bulletin, 1981, Volume: 17, Issue:1 Topics: Adult; Age Factors; Anthracenes; Clinical Trials as Topic; Depressive Disorder; Humans; Imipramine; Maprotiline	1981

Other Studies

100 other study(ies) available for imipramine and maprotiline

Article	Year
Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography. Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16 Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Enzyme Inhibitors; Histamine H1 Antagonists; Micelles; Models, Biological; Norepinephrine; Rats; Receptors, Adrenergic, alpha-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Structure-Activity Relationship	1999
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4 Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity	2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2004, Volume: 29, Issue:10 Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Electrophysiology; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Proteins; Heart; Humans; Myocardium; Oocytes; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; RNA, Messenger; Xenopus laevis	2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets. Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1 Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics	2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain. RSC medicinal chemistry, 2022, Feb-23, Volume: 13, Issue:2 Topics:	2022
Some aspects of the psychopharmacological activity of maprotiline (Ludiomil): effects of single and repeated treatments. The Journal of international medical research, 1978, Volume: 6, Issue:6 Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Anthracenes; Behavior, Animal; Body Temperature; Clomipramine; Depression, Chemical; Escape Reaction; Haplorhini; Head; Imipramine; Maprotiline; Mice; Muscle Contraction; Phenobarbital; Propranolol; Rats; Reserpine; Shrews	1978
Seizure activity in photosensitive baboons following antidepressant drugs and the role of serotoninergic mechanisms. Psychopharmacology, 1977, Jan-31, Volume: 51, Issue:2 Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Electroencephalography; Haplorhini; Imipramine; Isoquinolines; Maprotiline; Papio; Photic Stimulation; Seizures; Serotonin; Time Factors	1977
Response to sleep deprivation as a predictor of therapeutic results with antidepressant drugs. The American journal of psychiatry, 1979, Volume: 136, Issue:9 Topics: Antidepressive Agents, Tricyclic; Clomipramine; Depression; Female; Humans; Imipramine; Male; Maprotiline; Probability; Sleep Deprivation	1979
Epileptic phenomena induced in the cat by the antidepressants maprotiline, imipramine, clomipramine, and amitriptyline. Biological psychiatry, 1979, Volume: 14, Issue:3 Topics: Amitriptyline; Animals; Anthracenes; Cats; Cerebral Cortex; Clomipramine; Electroencephalography; Evoked Potentials; Female; Hippocampus; Imipramine; Male; Maprotiline; Reticular Formation; Seizures	1979
Guidelines for clinical use in interpreting tricyclic plasma levels. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1979, Volume: 24, Issue:6 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Dose-Response Relationship, Drug; Humans; Imipramine; Maprotiline; Nortriptyline	1979
Modulation of dopamine-mediated behavioural responses by antidepressants: effects of single and repeated treatment. European journal of pharmacology, 1979, Oct-15, Volume: 58, Issue:4 Topics: Amitriptyline; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Clomipramine; Dopamine; Humans; Hydroxydopamines; Imipramine; Male; Maprotiline; Rats; Rats, Inbred Strains; Stereotyped Behavior; Time Factors	1979
Plasma levels of tricyclic antidepressants and clinical efficacy: review of the literature -- part II. The Journal of clinical psychiatry, 1979, Volume: 40, Issue:2 Topics: Antidepressive Agents, Tricyclic; Biotransformation; Clomipramine; Depression; Desipramine; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Doxepin; Drug Interactions; Humans; Imipramine; Maprotiline; Protriptyline	1979
[Interaction between maprotiline and imipramine with norepinephrine on rat isolated aorta (author's transl)]. Archivos de farmacologia y toxicologia, 1977, Volume: 3, Issue:3 Topics: Animals; Anthracenes; Aorta, Thoracic; Drug Antagonism; Drug Evaluation; Imipramine; Male; Maprotiline; Norepinephrine; Rats	1977
Relative toxicity of amitriptyline, imipramine, maprotiline and mianserin after intravenous infusion in conscious rabbits. British journal of clinical pharmacology, 1978, Volume: 5 Suppl 1 Topics: Amitriptyline; Animals; Anthracenes; Central Nervous System; Dibenzazepines; Dose-Response Relationship, Drug; Female; Heart; Imipramine; Male; Maprotiline; Mianserin; Rabbits	1978
Cardiotoxicity of tricyclic antidepressants and maprotiline in the chick embryo. A comparative study. Activitas nervosa superior, 1978, Volume: 20, Issue:1 Topics: Amitriptyline; Animals; Anthracenes; Antidepressive Agents, Tricyclic; Chick Embryo; Dothiepin; Heart Arrest; Imipramine; Lethal Dose 50; Maprotiline; Myocardial Contraction	1978
[Comparative study of cardiotoxicity induced by maprotiline and imipramine in vitro: mechanism of action]. Archivos de farmacologia y toxicologia, 1978, Volume: 4, Issue:1 Topics: Animals; Anthracenes; Calcium; Cell Membrane; Heart Conduction System; Heart Rate; Imipramine; In Vitro Techniques; Maprotiline; Myocardial Contraction; Myocardium; Potassium; Rats	1978
The relative toxicity of amitriptyline, imipramine, maprotiline and mianserin in rabbits in vivo. British journal of pharmacology, 1979, Volume: 65, Issue:2 Topics: Amitriptyline; Anesthesia; Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Behavior, Animal; Blood Pressure; Electrocardiography; Female; Heart Rate; Imipramine; Male; Maprotiline; Mianserin; Rabbits; Seizures	1979
Variance analysis of error in selected ion monitoring assays using various internal standards. A practical study case. Biomedical mass spectrometry, 1977, Volume: 4, Issue:2 Topics: Analysis of Variance; Chromatography, Gas; Desipramine; Imipramine; Maprotiline; Mass Spectrometry; Methods; Promazine; Regression Analysis; Time Factors	1977
Effect of nomifensine on brain amines and epilepsy in photosensitive baboons. British journal of clinical pharmacology, 1977, Volume: 4Suppl 2 Topics: Amines; Animals; Brain Chemistry; Clomipramine; Dose-Response Relationship, Drug; Imipramine; Isoquinolines; Maprotiline; Nomifensine; Papio; Photic Stimulation; Seizures	1977
[Some pharmacological effects of maprotiline (Ciba 34.276 Ba) (author's transl)]. Archivos de farmacologia y toxicologia, 1977, Volume: 3, Issue:2 Topics: Animals; Anthracenes; Blood Pressure; Female; Imipramine; In Vitro Techniques; Male; Maprotiline; Rats; Stomach; Uterus	1977
[Comparative effects maprotiline and imipramine on the in vivo uptake of H3Na of brain, heart and spleen of mice]. Archivos de farmacologia y toxicologia, 1976, Volume: 2, Issue:2 Topics: Animals; Anthracenes; Brain Chemistry; Heart; Imipramine; Maprotiline; Mice; Sodium; Spleen; Tritium	1976
Pharmacological studies of drug action on CNS, with special reference to effects of maprotiline. International journal of clinical pharmacology and biopharmacy, 1975, Volume: 11, Issue:3 Topics: Action Potentials; Amitriptyline; Animals; Anthracenes; Antiemetics; Apomorphine; Body Weight; Cats; Chlorpromazine; Crowding; Dogs; Humans; Imipramine; Male; Maprotiline; Methamphetamine; Mice; Mice, Inbred Strains; Motor Activity; Rats; Reflex; Reflex, Monosynaptic; Spatial Behavior; Spinal Cord; Stereotyped Behavior	1975
Proceedings: The effect of maprotiline and imipramine on sleep cycles in rats. Activitas nervosa superior, 1975, Volume: 17, Issue:4 Topics: Animals; Anthracenes; Imipramine; Male; Maprotiline; Rats; Sleep; Sleep Stages; Time Factors	1975
[Behavior pharmacology of maprotiline, a new antidepressant]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1975, Volume: 71, Issue:8 Topics: Aggression; Amitriptyline; Animals; Anthracenes; Apomorphine; Behavior, Animal; Body Temperature; Catalepsy; Escape Reaction; Eyelids; Haloperidol; Humans; Imipramine; Levodopa; Maprotiline; Methamphetamine; Mice; Motor Activity; Oxotremorine; Physostigmine; Rats; Reserpine; Sleep; Tetrabenazine	1975
[Proceedings: Effect of tricyclic antidepressive agents and of Nomifensin (Hoe984) on the contractile properties of the isolated papillary muscle and on the tonus of the smooth vascular muscles]. Zeitschrift fur Kardiologie, 1975, Volume: Suppl 2 Topics: Acridines; Animals; Anthracenes; Antidepressive Agents, Tricyclic; Cats; Desipramine; Imipramine; Isoquinolines; Maprotiline; Muscle Contraction; Muscle, Smooth; Papillary Muscles; Rats	1975
The effect of antidepressant drugs on the locomotor hyperactivity induced by MK-801, a non-competitive NMDA receptor antagonist. Neuropharmacology, 1992, Volume: 31, Issue:7 Topics: Animals; Antidepressive Agents; Benzazepines; Citalopram; Dizocilpine Maleate; Fluoxetine; Imipramine; Isomerism; Male; Maprotiline; Motor Activity; Prazosin; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Sulpiride	1992
[Electroencephalographic and cardiovascular effects of milnaciplan hydrochloride (TN-912), a novel antidepressant]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1991, Volume: 98, Issue:5 Topics: Animals; Antidepressive Agents; Blood Pressure; Brain; Cyclopropanes; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Electroencephalography; Guinea Pigs; Heart Rate; Imipramine; In Vitro Techniques; Male; Maprotiline; Milnacipran; Myocardial Contraction; Rats; Rats, Inbred Strains; Respiration	1991
High-affinity [3H]6-nitroquipazine binding to the 5-hydroxytryptamine transport system in rat lung. Biochemical pharmacology, 1991, Jun-01, Volume: 41, Issue:11 Topics: Animals; Biological Transport; Desipramine; Imipramine; Kinetics; Lung; Male; Maprotiline; Membranes; Quipazine; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Temperature; Tritium; Zimeldine	1991
3H-imipramine binding to freshly prepared platelet membranes in depression. Psychiatry research, 1989, Volume: 29, Issue:1 Topics: Adult; Aged; Bipolar Disorder; Blood Platelets; Carrier Proteins; Depressive Disorder; Dexamethasone; Electroconvulsive Therapy; Female; Humans; Hydrocortisone; Imipramine; Male; Maprotiline; Menopause; Middle Aged; Receptors, Drug; Receptors, Neurotransmitter; Seasons	1989
The influence of repeated treatment with imipramine, (+)- and (-)-oxaprotiline on behavioural effects of dopamine D-1 and D-2 agonists. Journal of neural transmission, 1989, Volume: 76, Issue:1 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Anthracenes; Antidepressive Agents; Benzazepines; Dopamine Agents; Drug Interactions; Ergolines; Grooming; Imipramine; Male; Maprotiline; Motor Activity; Nucleus Accumbens; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Reference Values; Stereoisomerism	1989
Antidepressant drugs potentiate the alpha 1-adrenoceptor effect in hippocampal slices. European journal of pharmacology, 1989, Jul-18, Volume: 166, Issue:2 Topics: Animals; Antidepressive Agents; Hippocampus; Imipramine; In Vitro Techniques; Male; Maprotiline; Mianserin; Neurons; Neurotransmitter Agents; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha	1989
An adult case of psychogenic alopecia universalis. The Japanese journal of psychiatry and neurology, 1989, Volume: 43, Issue:4 Topics: Adult; Alopecia; Anxiety Disorders; Depressive Disorder; Humans; Imipramine; Job Satisfaction; Male; Maprotiline; Marriage; Psychophysiologic Disorders; Self Concept; Stress, Psychological	1989
Effect of a protracted antidepressant treatment on signal transduction and [3H](-)-baclofen binding at GABAB receptors. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:1 Topics: Adenylyl Cyclases; Animals; Anthracenes; Baclofen; Cerebral Cortex; Colforsin; Desipramine; Drug Administration Schedule; Imipramine; Injections, Intraperitoneal; Kinetics; Male; Maprotiline; Rats; Rats, Inbred Strains; Receptors, GABA-A	1987
Inhibition of 22Na influx by tricyclic and tetracyclic antidepressants and binding of [3H]imipramine in bovine adrenal medullary cells. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:1 Topics: Adrenal Medulla; Amitriptyline; Animals; Anthracenes; Calcium; Carrier Proteins; Catecholamines; Cattle; Cells, Cultured; Imipramine; Kinetics; Maprotiline; Mianserin; Nortriptyline; Receptors, Drug; Receptors, Neurotransmitter; Sodium; Sodium Radioisotopes; Structure-Activity Relationship; Tritium	1987
Does platelet serotonin receptor supersensitivity accompany endogenous depression? Biological psychiatry, 1989, Feb-15, Volume: 25, Issue:4 Topics: Adult; Antidepressive Agents; Bipolar Disorder; Blood Platelets; Carbazoles; Depressive Disorder; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Platelet Aggregation; Receptors, Serotonin; Serotonin	1989
Changes in [3H]5-HT uptake and [3H]imipramine binding in platelets after chlorimipramine in healthy volunteers. Comparison with maprotiline and amineptine. Biological psychiatry, 1987, Volume: 22, Issue:3 Topics: Adult; Blood Platelets; Carrier Proteins; Clomipramine; Dibenzocycloheptenes; Female; Humans; Imipramine; Kinetics; Male; Maprotiline; Middle Aged; Receptors, Drug; Receptors, Neurotransmitter; Serotonin	1987
High levels of tricyclic antidepressants in conventional therapy: determinant factors. International journal of clinical pharmacology, therapy, and toxicology, 1988, Volume: 26, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline; Risk Factors	1988
Selectivity in the binding of psychotropic drugs to the variants of alpha-1 acid glycoprotein. Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:2 Topics: Amitriptyline; Clomipramine; Desipramine; Hydrogen-Ion Concentration; Imipramine; Maprotiline; Methadone; Orosomucoid; Psychotropic Drugs; Thioridazine; Trimipramine	1988
Comparison of the chronotropic responses to tri- and tetracyclic antidepressants in isolated sinoatrial node preparations from the rabbit. Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 289, Issue:1 Topics: Action Potentials; Animals; Anthracenes; Female; Heart Rate; Imipramine; In Vitro Techniques; Male; Maprotiline; Membrane Potentials; Mianserin; Microelectrodes; Rabbits; Sinoatrial Node	1987
Successful utilization of maprotiline in a panic disorder patient intolerant of tricyclics. Journal of clinical psychopharmacology, 1987, Volume: 7, Issue:2 Topics: Anthracenes; Drug Tolerance; Fear; Female; Humans; Imipramine; Maprotiline; Middle Aged; Panic	1987
Effects of subchronic administration of psychoactive substances on the circadian rhythm of urinary corticosterone excretion in rats. Psychoneuroendocrinology, 1985, Volume: 10, Issue:4 Topics: Animals; Antidepressive Agents; Circadian Rhythm; Clorgyline; Corticosterone; Fluoxetine; Imipramine; Male; Maprotiline; Pargyline; Propylamines; Rats; Trimipramine	1985
Acute effects of antidepressants on hippocampal seizures. Annals of neurology, 1985, Volume: 18, Issue:6 Topics: Amitriptyline; Animals; Anticonvulsants; Antidepressive Agents; Bupropion; Desipramine; Epilepsy; Hippocampus; Imipramine; Maprotiline; Propiophenones; Rats; Trazodone	1985
Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice. Neuropharmacology, 1985, Volume: 24, Issue:4 Topics: Acridines; Amitriptyline; Animals; Antidepressive Agents; Depressive Disorder; Desipramine; Diphenhydramine; Disease Models, Animal; Electroshock; Ethanol; Humans; Imipramine; Male; Maprotiline; Mianserin; Mice; Motor Activity; Nialamide; Pargyline; Tranylcypromine	1985
[Electroencephalographic study of maprotiline, a new antidepressive agent]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1974, Volume: 70, Issue:6 Topics: Acoustic Stimulation; Amitriptyline; Amygdala; Animals; Anthracenes; Antidepressive Agents; Cerebral Cortex; Chlorpromazine; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Hippocampus; Imipramine; Male; Maprotiline; Mesencephalon; Physostigmine; Rabbits; Reticular Formation; Thalamic Nuclei; Theta Rhythm	1974
Dexamethasone suppression test as a predictor of drug treatment response. Progress in neuro-psychopharmacology & biological psychiatry, 1984, Volume: 8, Issue:4-6 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Dexamethasone; Dibenzazepines; Female; Humans; Imipramine; Maprotiline	1984
Attenuation of the post-decapitation convulsions after repeated treatment of rats with desipramine, imipramine and maprotiline. Acta pharmacologica et toxicologica, 1984, Volume: 54, Issue:5 Topics: Alanine; Animals; Anticonvulsants; Antidepressive Agents; Desipramine; Imipramine; Male; Maprotiline; Rats; Rats, Inbred Strains; Time Factors; Zimeldine	1984
Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model. Neuropsychobiology, 1984, Volume: 12, Issue:4 Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Fluvoxamine; Imipramine; Male; Maprotiline; Mianserin; Oximes; Rats; Rats, Inbred Strains; Seizures; Viloxazine	1984
Simultaneous measurement of various antidepressants in the plasma of depressed patients by high performance liquid chromatography. Folia psychiatrica et neurologica japonica, 1984, Volume: 38, Issue:1 Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents; Chromatography, High Pressure Liquid; Clomipramine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline	1984
Facial EMG activity levels predict treatment outcome in depression. Psychiatry research, 1984, Volume: 13, Issue:4 Topics: Amitriptyline; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Electromyography; Facial Expression; Facial Muscles; Female; Humans; Imipramine; Maprotiline; Middle Aged; Muscle Contraction; Prognosis; Psychiatric Status Rating Scales	1984
[The child who is suddenly confused and hallucinating]. Nederlands tijdschrift voor geneeskunde, 1983, Aug-20, Volume: 127, Issue:34 Topics: Anthracenes; Child; Cognition Disorders; Confusion; Drug Synergism; Hallucinations; Humans; Imipramine; Male; Maprotiline; Promethazine	1983
Comparison of single-dose pharmacokinetics of imipramine and maprotiline in the elderly. Psychopharmacology, 1980, Volume: 70, Issue:1 Topics: Aged; Anthracenes; Biological Availability; Desipramine; Female; Half-Life; Hemodynamics; Humans; Imipramine; Kinetics; Maprotiline	1980
Maprotiline versus imipramine. The Journal of clinical psychiatry, 1982, Volume: 43, Issue:3 Topics: Anthracenes; Depressive Disorder; Humans; Imipramine; Maprotiline	1982
To the pharmacological profile of maprotiline. Activitas nervosa superior, 1982, Volume: 24, Issue:2 Topics: Abnormalities, Drug-Induced; Adult; Animals; Anthracenes; Arousal; Chick Embryo; Depressive Disorder; Dose-Response Relationship, Drug; Female; Heart Arrest; Humans; Imipramine; Male; Maprotiline; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Sleep Stages	1982
[Treatment of involutional depression with maprotiline]. Activitas nervosa superior, 1982, Volume: 24, Issue:2 Topics: Aged; Anthracenes; Depressive Disorder, Major; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged	1982
[The effect of maprotiline on target symptoms of depressive states]. Activitas nervosa superior, 1982, Volume: 24, Issue:2 Topics: Adolescent; Adult; Aged; Anthracenes; Depressive Disorder; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Psychiatric Status Rating Scales	1982
The effects of antidepressants on aggressiveness induced by social deprivation in mice. Pharmacology, biochemistry, and behavior, 1981, Volume: 14 Suppl 1 Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Humans; Imipramine; Maprotiline; Mice; Social Isolation	1981
[Paradoxical akinesia induced by antidepressant drugs (author's transl)]. Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1980, Volume: 13, Issue:6 Topics: Aged; Antidepressive Agents, Tricyclic; Catalepsy; Cataplexy; Depressive Disorder; Dyskinesia, Drug-Induced; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged	1980
Possible pathophysiological mechanisms in subtypes of unipolar depressive disorders based on differences in urinary MHPG levels [proceedings]. Psychopharmacology bulletin, 1981, Volume: 17, Issue:1 Topics: Depressive Disorder; Glycols; Humans; Hydrocortisone; Imipramine; Maprotiline; Methoxyhydroxyphenylglycol; Norepinephrine; Statistics as Topic	1981
Lithium treatment and prophylaxis in unipolar depression. Psychosomatics, 1980, Volume: 21, Issue:4 Topics: Acute Disease; Depression; Humans; Imipramine; Lithium; Maprotiline; Recurrence	1980
[Effect of the antidepressants imipramine and maprotiline on the electrically-induced contraction of rat aorta (author's transl)]. Archivos de farmacologia y toxicologia, 1980, Volume: 6, Issue:1 Topics: Animals; Anthracenes; Aorta; Drug Interactions; Electric Stimulation; Imipramine; In Vitro Techniques; Male; Maprotiline; Muscle Contraction; Muscle, Smooth, Vascular; Rats	1980
MHPG as a predictor of antidepressant response to imipramine and maprotiline. The American journal of psychiatry, 1980, Volume: 137, Issue:9 Topics: Adult; Anthracenes; Depressive Disorder; Female; Glycols; Humans; Imipramine; Male; Maprotiline; Methoxyhydroxyphenylglycol; Middle Aged	1980
Effect of p-chlorophenylalanine and alpha-methyltyrosine on the antinociceptive effect of antidepressant drugs. Pharmacology & toxicology, 1995, Volume: 77, Issue:4 Topics: Acetates; Acetic Acid; alpha-Methyltyrosine; Analgesia; Animals; Antidepressive Agents; Clomipramine; Drug Interactions; Fenclonine; Imipramine; Injections, Intraventricular; Maprotiline; Methyltyrosines; Mice; Norepinephrine; Random Allocation; Serotonin; Serotonin Agents; Zimeldine	1995
Interaction of opioids with antidepressant-induced antinociception. Psychopharmacology, 1995, Volume: 122, Issue:4 Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Clomipramine; Drug Combinations; Female; Imipramine; Male; Maprotiline; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pain Measurement; Random Allocation; Selective Serotonin Reuptake Inhibitors; Zimeldine	1995
Different effects of the antidepressant drugs imipramine, maprotiline and bupropion on insulin secretion from mouse pancreatic islets. Arzneimittel-Forschung, 1996, Volume: 46, Issue:7 Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bupropion; Female; Glucose; Imipramine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Maprotiline; Mice	1996
The Pisa syndrome (pleurothotonus) during antidepressant therapy. Biological psychiatry, 1997, Jan-15, Volume: 41, Issue:2 Topics: Amitriptyline; Antidepressive Agents; Biperiden; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline; Orientation; Postural Balance; Posture	1997
Partial role of 5-HT2 and 5-HT3 receptors in the activity of antidepressants in the mouse forced swimming test. European journal of pharmacology, 1997, May-01, Volume: 325, Issue:2-3 Topics: Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Desipramine; Drug Interactions; Fluoxetine; Fluvoxamine; Imipramine; Ketanserin; Male; Maprotiline; Mice; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming	1997
Repeated administration of antidepressant drugs affects the levels of mRNA coding for D1 and D2 dopamine receptors in the rat brain. Journal of neural transmission (Vienna, Austria : 1996), 1997, Volume: 104, Issue:4-5 Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Brain; Citalopram; Imipramine; Male; Maprotiline; Norepinephrine; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Selective Serotonin Reuptake Inhibitors	1997
Acute lung failure induced by tricyclic antidepressants. Toxicology and applied pharmacology, 1997, Volume: 146, Issue:2 Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Overdose; Imipramine; Lung; Maprotiline; Mianserin; Microscopy, Electron; Nortriptyline; Organ Size; Perfusion; Pulmonary Edema; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley	1997
Sensitive and rapid method for the simultaneous quantification of five antidepressants with their respective metabolites in plasma using high-performance liquid chromatography with diode-array detection. Journal of chromatography. B, Biomedical sciences and applications, 1997, Oct-24, Volume: 700, Issue:1-2 Topics: Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Fluoxetine; Humans; Imipramine; Maprotiline; Sensitivity and Specificity; Spectrophotometry, Ultraviolet	1997
Mechanism of block of cardiac transient outward K+ current (I(to)) by antidepressant drugs. Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:4 Topics: Action Potentials; Amitriptyline; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Binding Sites; Dose-Response Relationship, Drug; Drug Interactions; Heart Ventricles; Imipramine; Maprotiline; Mianserin; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Wistar; Structure-Activity Relationship; Trazodone; Ventricular Function	1998
The inhibition of monoamine oxidase activity by various antidepressants: differences found in various mammalian species. Japanese journal of pharmacology, 1999, Volume: 81, Issue:1 Topics: Animals; Antidepressive Agents; Binding, Competitive; Brain; Dogs; Imipramine; Isoenzymes; Kinetics; Macaca; Male; Maprotiline; Mice; Mitochondria; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nomifensine; Rats; Rats, Wistar; Species Specificity; Zimeldine	1999
Inhibition of monkey brain semicarbazide-sensitive amine oxidase by various antidepressants. Neuroscience letters, 2000, Jun-02, Volume: 286, Issue:2 Topics: Adrenergic Uptake Inhibitors; Amine Oxidase (Copper-Containing); Animals; Antidepressive Agents; Brain; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Imipramine; Macaca; Male; Maprotiline; Neurons; Nomifensine; Selective Serotonin Reuptake Inhibitors; Time Factors; Zimeldine	2000
Imipramine, mianserine and maprotiline block delayed rectifier potassium current in ventricular myocytes. Pharmacological research, 2002, Volume: 45, Issue:2 Topics: Action Potentials; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Delayed Rectifier Potassium Channels; Dose-Response Relationship, Drug; Heart Ventricles; Imipramine; Maprotiline; Mianserin; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Rats; Rats, Wistar; Ventricular Function	2002
Neurochemical and behavioural characterization of milnacipran, a serotonin and noradrenaline reuptake inhibitor in rats. Psychopharmacology, 2002, Volume: 162, Issue:3 Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Behavior, Animal; Binding, Competitive; Brain Chemistry; Conditioning, Psychological; Cyclopropanes; Dose-Response Relationship, Drug; Fear; Fluoxetine; Fluvoxamine; Imipramine; Male; Maprotiline; Microdialysis; Milnacipran; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Prefrontal Cortex; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Cell Surface; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Swimming; Synaptosomes; Time Factors	2002
Screening antidepressants in the chick separation-stress paradigm. Psychopharmacology, 2005, Volume: 181, Issue:1 Topics: Animals; Antidepressive Agents; Anxiety, Separation; Chickens; Citalopram; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Imipramine; Maprotiline; Phenelzine; Sleep Wake Disorders; Stress, Psychological	2005
Reduction of Submissive Behavior Model for antidepressant drug activity testing: study using a video-tracking system. Behavioural pharmacology, 2005, Volume: 16, Issue:8 Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Competitive Behavior; Dominance-Subordination; Feeding Behavior; Fluoxetine; Imipramine; Maprotiline; Mice; Naltrexone; Narcotic Antagonists; Rats	2005
Modelling the anxiety-depression continuum in chicks. Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:2 Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Chickens; Chlordiazepoxide; Clonidine; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoxetine; Imipramine; Interleukin-6; Maprotiline; Social Isolation; Stress, Psychological	2009
Mouse strain differences in the unpredictable chronic mild stress: a four-antidepressant survey. Behavioural brain research, 2008, Nov-03, Volume: 193, Issue:1 Topics: Animals; Animals, Outbred Strains; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; Chronic Disease; Depression; Desipramine; Fluoxetine; Grooming; Imipramine; Injections, Intraperitoneal; Male; Maprotiline; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Selective Serotonin Reuptake Inhibitors; Species Specificity; Stress, Psychological; Time Factors	2008
Antidepressant stimulation of CDP-diacylglycerol synthesis does not require monoamine reuptake inhibition. BMC neuroscience, 2010, Jan-27, Volume: 11 Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Cerebral Cortex; Cytidine Diphosphate Diglycerides; Diacylglycerol Cholinephosphotransferase; Dose-Response Relationship, Drug; Hippocampus; Imipramine; Male; Maprotiline; Mice; Mice, Inbred C57BL; Paroxetine; PC12 Cells; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins	2010
Antidepressants that inhibit both serotonin and norepinephrine reuptake impair long-term potentiation in hippocampus. Psychopharmacology, 2014, Volume: 231, Issue:23 Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cyclohexanols; Fluoxetine; Hippocampus; Imipramine; Long-Term Potentiation; Male; Maprotiline; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptic Transmission; Venlafaxine Hydrochloride	2014
Effects of the LC mobile phase in vacuum differential mobility spectrometry-mass spectrometry for the selective analysis of antidepressant drugs in human plasma. Analytical and bioanalytical chemistry, 2022, Volume: 414, Issue:24 Topics: Acetonitriles; Amitriptyline; Antidepressive Agents; Desipramine; Humans; Imipramine; Maprotiline; Mass Spectrometry; Methanol; Nortriptyline; Reproducibility of Results; Spectrum Analysis; Vacuum; Venlafaxine Hydrochloride	2022
On-Chip Electromembrane Surrounded Solid Phase Microextraction for Determination of Tricyclic Antidepressants from Biological Fluids Using Poly(3,4-ethylenedioxythiophene)-Graphene Oxide Nanocomposite as a Fiber Coating. Biosensors, 2023, Jan-14, Volume: 13, Issue:1 Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Desipramine; Humans; Imipramine; Limit of Detection; Maprotiline; Nanocomposites; Nortriptyline; Reproducibility of Results; Sertraline; Solid Phase Microextraction	2023