Compounds > imipramine

imipramine and lofepramine

imipramine has been researched along with lofepramine in 16 studies

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (37.50)	18.7374
1990's	5 (31.25)	18.2507
2000's	2 (12.50)	29.6817
2010's	3 (18.75)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Hopes, H; Lehmann, E	1
Healy, D; Horton, RW; Kerry, SM; Lawrence, KM; Paykel, ES; Theodorou, AE; White, W; Whitehouse, AM; Wilton-Cox, H	2
Carrón, R; Delpón, E; Pérez-Vizcaino, F; Tamargo, J	1
Leonard, BE	1
Dorman, T	1
Dutt, JE; Feighner, JP; Hendrickson, GG; Meridith, CH	1
Csanalosi, I; Rickels, K; Weise, CC; Werblowsky, J; Zal, HM	1
Dutt, JE	1
Gunnarsson, PO; Strandgården, K	1
Kelly, JP; Leonard, BE	1

Reviews

1 review(s) available for imipramine and lofepramine

Article	Year
Lofepramine: pharmacology and mode of action. International clinical psychopharmacology, 1988, Volume: 3 Suppl 2 Topics: Amitriptyline; Animals; Behavior, Animal; Brain; Chemical Phenomena; Chemistry; Dibenzazepines; Imipramine; Lofepramine; Rats; Synaptic Transmission	1988

Trials

4 trial(s) available for imipramine and lofepramine

Article	Year
Differential effects of a single dose of imipramine and lopramine in healthy subjects varying in their level of depression. Progress in neuro-psychopharmacology, 1977, Volume: 1, Issue:1-2 Topics: Adult; Clinical Trials as Topic; Depression; Dibenzazepines; Drug Evaluation; Humans; Imipramine; Lofepramine; Male; Placebos	1977
Toxicity of tricyclic antidepressants: are there important differences? The Journal of international medical research, 1985, Volume: 13, Issue:2 Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cardiovascular System; Clinical Trials as Topic; Dothiepin; Humans; Imipramine; Lofepramine; Rats; Suicide; United Kingdom	1985
A double blind comparison of lofepramine, imipramine and placebo in patients with depression. Acta psychiatrica Scandinavica, 1982, Volume: 66, Issue:2 Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Dibenzazepines; Double-Blind Method; Female; Humans; Imipramine; Lofepramine; Male; Middle Aged; Placebos	1982
Lofepramine and imipramine in unipolar depressed outpatients. A placebo controlled study. Acta psychiatrica Scandinavica, 1982, Volume: 66, Issue:2 Topics: Adult; Clinical Trials as Topic; Depressive Disorder; Dibenzazepines; Double-Blind Method; Female; Humans; Imipramine; Lofepramine; Male; Middle Aged; Outpatients; Random Allocation; Sleep Stages	1982

Other Studies

11 other study(ies) available for imipramine and lofepramine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Platelet alpha 2-adrenoceptors, defined with agonist and antagonist ligands, in depressed patients, prior to and following treatment. Journal of affective disorders, 1991, Volume: 23, Issue:3 Topics: Adrenergic alpha-Agonists; Binding, Competitive; Blood Platelets; Brimonidine Tartrate; Depressive Disorder; Electroconvulsive Therapy; Humans; Imipramine; Lofepramine; Psychiatric Status Rating Scales; Quinoxalines; Radioligand Assay; Receptors, Adrenergic; Yohimbine	1991
Effects of (S)-nafenodone, a new antidepressant, in isolated guinea-pig atrial and ventricular muscle fibres. European journal of pharmacology, 1991, Jun-18, Volume: 199, Issue:1 Topics: Action Potentials; Animals; Antidepressive Agents; Calcium; Desipramine; Female; Guinea Pigs; Heart; Heart Atria; Heart Ventricles; Imipramine; In Vitro Techniques; Isoproterenol; Lofepramine; Male; Myocardial Contraction; Naphthalenes; Papillary Muscles; Refractory Period, Electrophysiological	1991
3H-imipramine binding to previously frozen platelet membranes from depressed patients, before and after treatment. The British journal of psychiatry : the journal of mental science, 1990, Volume: 157 Topics: Adult; Blood Platelets; Cell Membrane; Cohort Studies; Depressive Disorder; Dexamethasone; Electroconvulsive Therapy; Female; Humans; Hydrocortisone; Imipramine; Lofepramine; Male; Middle Aged; Seasons	1990
On the clinical response/serum level relationship for antidepressants II: Lofepramine and imipramine. Psychopharmacology bulletin, 1982, Volume: 18, Issue:2 Topics: Depression; Dibenzazepines; Humans; Imipramine; Lofepramine	1982
Metabolism of lofepramine and imipramine in liver microsomes from rat and man. Xenobiotica; the fate of foreign compounds in biological systems, 1994, Volume: 24, Issue:8 Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Biotransformation; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Humans; Imipramine; In Vitro Techniques; Lofepramine; Male; Microsomes, Liver; Middle Aged; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet	1994
An investigation of the antidepressant properties of lofepramine and its desmethylated metabolites in the forced swim and olfactory bulbectomized rat models of depression. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 9, Issue:1-2 Topics: Animals; Antidepressive Agents, Tricyclic; Depression; Desipramine; Dose-Response Relationship, Drug; Imipramine; Lofepramine; Male; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Swimming	1999