imipramine and levodopa

imipramine has been researched along with levodopa in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199031 (73.81)18.7374
1990's1 (2.38)18.2507
2000's4 (9.52)29.6817
2010's6 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Anand, M; Bhargava, KP; Gupta, GP1
Bissada, NK; Finkbeiner, AE; Welch, LT1
Gershon, S; Hine, B; Wallach, MB1
Benkert, O1
Brambilla, F; Guastalla, A; Maffei, C; Nobile, P; Ponzano, M; Rovere, C; Scarone, S1
Baldini, A; Ciottoli, GB; Lisciani, R1
Moore, KE; Wuerthele, SM1
Patil, PN; Rahwan, RG; Salazar, M1
Lippman, W; Pugsley, TA1
Fujiwara, M; Inoue, K; Ueki, S1
Knopp, W; Messiha, FS1
Eplov, L; Nielsen, M; Scheel-Krüger, J1
Morgan, JP; Nathan, G; Rivera-Calimlim, L; Trabert, N1
Bhaskar, EA; Bhaskar, PA; Jagannathan, K1
Angrist, B; Gershon, S; Shopsin, B1
Messiha, F; Morgan, JP; Rivera-Calimlim, L; Sundaresan, PR; Trabert, N1
Fukushima, N1
Fujiwara, M; Ibii, N; Inoue, K; Kataoka, Y; Ueki, S1
Bizière, K; Kan, JP; Roncucci, R; Wermuth, CG; Worms, P1
Braz, S; Ferreira, TM; Silveira Filho, NG; Troncone, LR; Tufik, S1
Carvey, PM; Goetz, CG; Klawans, HL; Tanner, CM1
Díez de los Rios, A; Labajos, M; Morell, M; Souviron, A1
Ginestet, D1
Chase, TN1
Markham, CH1
Chapman, B; Feldman, JM1
Hori, A; Kariya, T; Nakagawara, M; Watanabe, A1
Dalphrase, F; DeFeudis, FV; Deniard, MJ; Grognet, A; Meignen, J; Roux, E1
Deguchi, T; Sakai, Y1
Edwards, M1
Golbe, LI; Nieforth, KA1

Reviews

3 review(s) available for imipramine and levodopa

ArticleYear
Uropharmacology: X. Central nervous system stimulants and depressants.
    Urology, 1979, Volume: 13, Issue:4

    Topics: Amphetamines; Anesthetics; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Baclofen; Benzodiazepines; Central Nervous System Agents; Chloral Hydrate; Humans; Imipramine; Levodopa; Meperidine; Meprobamate; Morphine; Nortriptyline; Paraldehyde; Phenothiazines; Phenytoin; Picrotoxin; Reserpine; Strychnine; Urinary Tract

1979
Serotonergic mechanisms and extrapyramidal function in man.
    Advances in neurology, 1974, Volume: 5

    Topics: 5-Hydroxytryptophan; Carbidopa; Cerebellar Diseases; Creutzfeldt-Jakob Syndrome; Down Syndrome; Extrapyramidal Tracts; Fenclonine; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Imipramine; Levodopa; Muscular Diseases; Paralysis; Parkinson Disease; Parkinson Disease, Secondary; Probenecid; Reserpine; Serotonin; Spinal Cord Diseases; Tetrabenazine; Time Factors

1974
[Therapy of Parkinsonism. II].
    La Clinica terapeutica, 1974, Nov-30, Volume: 71, Issue:4

    Topics: Amantadine; Amitriptyline; Humans; Imipramine; Levodopa; Parkinson Disease; Physical Therapy Modalities

1974

Trials

2 trial(s) available for imipramine and levodopa

ArticleYear
Studies on pituitary hormones and releasing hormones in depression and sexual impotence.
    Progress in brain research, 1975, Volume: 42

    Topics: 5-Hydroxytryptophan; Benserazide; Bipolar Disorder; Clinical Trials as Topic; Depression; Erectile Dysfunction; Female; Fenclonine; Humans; Imipramine; Insulin; Levodopa; Male; Pituitary Hormone-Releasing Hormones; Pituitary Hormones

1975
Catecholaminergic drugs in chronic schizophrenia.
    Neuropsychobiology, 1979, Volume: 5, Issue:4

    Topics: Adult; Apomorphine; Carbidopa; Chronic Disease; Clinical Trials as Topic; Drug Therapy, Combination; Follicle Stimulating Hormone; Growth Hormone; Humans; Hydrazines; Imipramine; Levodopa; Luteinizing Hormone; Male; Middle Aged; Placebos; Schizophrenia, Disorganized; Testosterone

1979

Other Studies

37 other study(ies) available for imipramine and levodopa

ArticleYear
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Modification of electroshock fighting by drugs known to interact with dopaminergic and noradrenergic neurons in normal and brain lesioned rats.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:7

    Topics: Aggression; Amantadine; Animals; Apomorphine; Brain; Ditiocarb; Dopamine; Electroshock; Humans; Imipramine; Levodopa; Male; Neurons; Norepinephrine; Rats; Reserpine

1977
Involvement of biogenic amines in drug-induced aggressive pecking in chicks.
    Psychopharmacologia, 1975, Sep-17, Volume: 43, Issue:3

    Topics: Aggression; Animals; Animals, Newborn; Antidepressive Agents; Biogenic Amines; Chickens; Dextroamphetamine; Dopamine; Female; Fenclonine; Haloperidol; Humans; Imipramine; Iprindole; Levodopa; Male; Methysergide; Pargyline; Phentolamine; Propranolol; Serotonin

1975
Behavioral study on the interactions between trazodone and L-dopa.
    Pharmacological research communications, 1979, Volume: 11, Issue:3

    Topics: Animals; Behavior, Animal; Drug Interactions; Female; Haloperidol; Imipramine; Levodopa; Male; Mice; Muscle Rigidity; Piperazines; Time Factors; Trazodone

1979
Studies on the mechanisms of L-dopa-induced depletion of 5-hydroxytryptamine in the mouse brain.
    Life sciences, 1977, May-15, Volume: 20, Issue:10

    Topics: Amines; Animals; Benztropine; Biological Transport; Brain; Clomipramine; Cocaine; Dihydroxyphenylalanine; Dopamine; Imipramine; Levodopa; Male; Mice; Mice, Inbred ICR; Serotonin; Tryptophan

1977
Binding of 14C-imipramine by pigmented and non-pigmented tissues.
    European journal of pharmacology, 1976, Volume: 38, Issue:2

    Topics: Animals; Brain; Female; Imipramine; In Vitro Techniques; Iris; Levodopa; Male; Melanins; Pigmentation; Rabbits; Time Factors

1976
Effects of viloxazine, an antidepressant agent, on biogenic amine uptake mechanisms and related activities.
    Canadian journal of physiology and pharmacology, 1976, Volume: 54, Issue:4

    Topics: Amitriptyline; Animals; Apomorphine; Biogenic Amines; Brain; Desipramine; Drug Synergism; Gastric Juice; Imipramine; In Vitro Techniques; Levodopa; Mice; Morpholines; Myocardium; Norepinephrine; Oxotremorine; Pupil; Rats; Reflex; Reserpine; Serotonin; Tyramine; Viloxazine

1976
[Behavioral pharmacology of a new antidepressant, lopramine].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1976, Volume: 72, Issue:5

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Apomorphine; Avoidance Learning; Blepharoptosis; Body Temperature; Catalepsy; Dibenzazepines; Drug Synergism; Emotions; Humans; Imipramine; Lethal Dose 50; Levodopa; Male; Methamphetamine; Mice; Motor Activity; Muscle Relaxation; Oxotremorine; Physostigmine; Rats; Stereotyped Behavior

1976
A study of endogenous dopamine metabolism in Gilles de la Tourette's disease.
    Diseases of the nervous system, 1976, Volume: 37, Issue:8

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Dopamine; Epinephrine; Haloperidol; Homovanillic Acid; Humans; Imipramine; Levodopa; Male; Tourette Syndrome

1976
The effect of amitriptyline, desipramine and imipramine on the vivo brain synthesis of 3H-noradrenaline from 3H-L-dopa in the rat.
    Psychopharmacologia, 1975, Volume: 41, Issue:3

    Topics: 3-Methoxy-4-hydroxyphenylethanol; 3,4-Dihydroxyphenylacetic Acid; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Benserazide; Brain; Chromatography, Thin Layer; Desipramine; Dopamine; Imipramine; Levodopa; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Normetanephrine; Rats; Tryptamines

1975
Imipramine-caused interference with levodopa absorption from the gastrointestinal tract in rats.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 192, Issue:2

    Topics: Animals; Biological Transport; Carbon Radioisotopes; Depression, Chemical; Duodenum; Gastric Mucosa; Ileum; Imipramine; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Jejunum; Levodopa; Male; Rats; Time Factors

1975
Augmenting procedures during L-dopa therapy for Parkinsonism.
    The Journal of the Association of Physicians of India, 1975, Volume: 23, Issue:1

    Topics: Antacids; Dextroamphetamine; Drug Synergism; Female; Humans; Imipramine; Levodopa; Male; Middle Aged; Parkinson Disease; Propranolol

1975
Drugs, diagnosis, and disease.
    Research publications - Association for Research in Nervous and Mental Disease, 1975, Volume: 54

    Topics: Acetylcholine; Amphetamines; Bipolar Disorder; Humans; Imipramine; Levodopa; Lithium; Methylphenidate; Monoamine Oxidase Inhibitors; Psychoses, Substance-Induced; Schizophrenia; Time Factors

1975
Imipramine-mediated interference with levodopa absorption from the gastrointestinal tract in man.
    Neurology, 1975, Volume: 25, Issue:11

    Topics: Adult; Depression, Chemical; Dopamine; Gastric Juice; Homovanillic Acid; Humans; Imipramine; Intestinal Absorption; Levodopa; Male; Polyethylene Glycols; Vanilmandelic Acid

1975
[Role of brain biogenic amines in the central thermoregulatory mechanism of the rat (author's transl)].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1975, Volume: 50, Issue:4

    Topics: Adaptation, Physiological; Animals; Biogenic Amines; Blood Glucose; Body Temperature Regulation; Cerebral Ventricles; Dopamine; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Haloperidol; Hydroxydopamines; Hypothermia; Imipramine; Isoproterenol; Levodopa; Male; Norepinephrine; Oxygen Consumption; Phenoxybenzamine; Phenylephrine; Propranolol; Rats; Rectum; Serotonin; Skin Temperature

1975
[Behavior pharmacology of maprotiline, a new antidepressant].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1975, Volume: 71, Issue:8

    Topics: Aggression; Amitriptyline; Animals; Anthracenes; Apomorphine; Behavior, Animal; Body Temperature; Catalepsy; Escape Reaction; Eyelids; Haloperidol; Humans; Imipramine; Levodopa; Maprotiline; Methamphetamine; Mice; Motor Activity; Oxotremorine; Physostigmine; Rats; Reserpine; Sleep; Tetrabenazine

1975
SR 95191, a selective inhibitor of type A monoamine oxidase with dopaminergic properties. I. Psychopharmacological profile in rodents.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1

    Topics: 5-Hydroxytryptophan; Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Body Temperature; Catalepsy; Clorgyline; Drug Interactions; Female; Haloperidol; Imipramine; Levodopa; Male; Mice; Moclobemide; Monoamine Oxidase Inhibitors; Motor Activity; Nomifensine; Oxotremorine; Pargyline; Piperidines; Pyridazines; Rats; Rats, Inbred Strains; Reserpine; Selegiline; Stereotyped Behavior

1987
Reversal of the increase in apomorphine-induced stereotypy and aggression in REM sleep deprived rats by dopamine agonist pretreatments.
    Psychopharmacology, 1988, Volume: 94, Issue:1

    Topics: Aggression; Amphetamine; Animals; Apomorphine; Bromocriptine; Carbidopa; Dopamine; Imipramine; Levodopa; Male; Nomifensine; Rats; Rats, Inbred Strains; Sleep Deprivation; Sleep, REM; Stereotyped Behavior

1988
Drug-induced myoclonus.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Anesthetics; Animals; Anti-Bacterial Agents; Antidepressive Agents; Bismuth; Carbidopa; Electroencephalography; Gasoline; Guinea Pigs; Humans; Hydrocarbons, Brominated; Imipramine; Levodopa; Methysergide; Models, Biological; Myoclonus; Parkinson Disease; Sleep

1986
Noradrenaline as a possible mediator of angiotensin II induced fluid transport in rat ileum in vitro.
    Revista espanola de fisiologia, 1986, Volume: 42, Issue:1

    Topics: Adrenalectomy; Angiotensin II; Animals; Body Water; Ileum; Imipramine; Intestinal Absorption; Levodopa; Male; Nephrectomy; Norepinephrine; Phentolamine; Rats; Rats, Inbred Strains; Sodium Chloride; Stimulation, Chemical

1986
The psychiatrist attitudes and therapeutic means when faced with resistant depressions.
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1974, Volume: 7, Issue:4

    Topics: Amitriptyline; Amphetamine; Antidepressive Agents; Autistic Disorder; Depression; Drug Resistance; Drug Therapy, Combination; Humans; Imipramine; Levodopa; Lithium; Suicide; Thyrotropin-Releasing Hormone

1974
The "on-off" side effect of L-DOPA.
    Advances in neurology, 1974, Volume: 5

    Topics: Age Factors; Amitriptyline; Aromatic Amino Acid Decarboxylase Inhibitors; Athetosis; Carbidopa; Catechol O-Methyltransferase Inhibitors; Chlordiazepoxide; Chorea; Desipramine; Diazepam; Dietary Proteins; Enzyme Inhibitors; Female; Humans; Imipramine; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Physical Exertion; Picolinic Acids; Prochlorperazine; Sex Factors; Stress, Psychological

1974
Mechanisms of catecholamine inactivation by the endocrine pancreas.
    Diabetes, 1974, Volume: 23, Issue:9

    Topics: Animals; Catechol O-Methyltransferase Inhibitors; Catecholamines; Cells, Cultured; Cocaine; Cricetinae; Culture Media; Dopamine; Drug Synergism; Imipramine; Insulin; Insulin Secretion; Islets of Langerhans; Levodopa; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nortriptyline; Pargyline; Rabbits; Rats; Species Specificity; Stimulation, Chemical; Tranylcypromine

1974
Effects of imipramine on behavior and brain norepinephrine metabolism in tetrabenazine treated rats: comparative study of a single administration with repeated administrations of imipramine.
    Folia psychiatrica et neurologica japonica, 1983, Volume: 37, Issue:4

    Topics: alpha-Methyltyrosine; Animals; Benserazide; Brain Chemistry; Drug Interactions; Glycols; Imipramine; Levodopa; Male; Methoxyhydroxyphenylglycol; Methyltyrosines; Rats; Rats, Inbred Strains; Tetrabenazine

1983
Pharmacological comparison of the potential antidepressant UP 614-04 with viloxazine and imipramine; behavioral studies.
    General pharmacology, 1982, Volume: 13, Issue:5

    Topics: Animals; Anticonvulsants; Antidepressive Agents; Apomorphine; Behavior, Animal; Body Temperature; Drug Interactions; Humans; Imipramine; Levodopa; Male; Mice; Morpholines; Motor Activity; Rats; Reserpine; Stereotyped Behavior; Tetrabenazine; Viloxazine

1982
[Effects of mianserin on functions of ascending and descending monoaminergic systems, using experimental models (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1980, Volume: 76, Issue:3

    Topics: 5-Hydroxytryptophan; Afferent Pathways; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Chlorpromazine; Dibenzazepines; Efferent Pathways; Imipramine; Levodopa; Male; Mianserin; Mice; Models, Neurological; Motor Activity; Rats; Reflex; Self Stimulation

1980
Adverse interaction of levodopa with tricyclic antidepressants.
    The Practitioner, 1982, Volume: 226, Issue:1370

    Topics: Aged; Amitriptyline; Carbidopa; Drug Combinations; Drug Interactions; Female; Humans; Imipramine; Levodopa; Parkinson Disease

1982
Retrospective study of drug response in 87 patients with progressive supranuclear palsy.
    Clinical neuropharmacology, 1993, Volume: 16, Issue:4

    Topics: Amitriptyline; Carbidopa; Humans; Imipramine; Levodopa; Retrospective Studies; Supranuclear Palsy, Progressive

1993