imipramine has been researched along with idazoxan in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 7 (50.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alexander, EJ; Bailey, DM; Castaldi, MJ; Ferrari, RA; Haubrich, DR; Luttinger, DA; Perrone, MH; Wentland, MP | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Ferrari, RA; Hamel, LT; Haubrich, DR; Perrone, MH | 1 |
| Howe, BB; Keith, RA; Salama, AI | 1 |
| Sanger, DJ | 1 |
| Amabeoku, G; Chandomba, R | 1 |
| Amabeoku, GJ | 1 |
| Hoffman, T; Jiménez-Rivera, CA; Santacana, G; Savage, DD; Segarra, O; Weiss, GK | 1 |
| Baker, RA; Brady, LS; Herkenham, M | 1 |
| McNamara, M; Nowak, G; Paul, IA; Piletz, JE; Redmond, A; Zhu, H | 1 |
| Arborelius, L; Bertilsson, L; Linnér, L; Nomikos, GG; Svensson, TH | 1 |
| Harvey, BH; Sallinen, J; Shahid, M; Uys, MM | 1 |
14 other study(ies) available for imipramine and idazoxan
| Article | Year |
|---|---|
Synthesis and antidepressant properties of novel 2-substituted 4,5-dihydro-1H-imidazole derivatives.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain; Chemical Phenomena; Chemistry; Dioxanes; Dopamine; Idazoxan; Imidazoles; Male; Mice; Muscle Contraction; Muscle, Smooth; Norepinephrine; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Structure-Activity Relationship; Tetrabenazine | 1987 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Napamezole, an alpha-2 adrenergic receptor antagonist and monoamine uptake inhibitor in vitro.
Topics: Adrenergic alpha-Antagonists; Amino Acids; Animals; Brain; Cells, Cultured; Clonidine; Dioxanes; Idazoxan; Imidazoles; Imipramine; Male; Neurotransmitter Uptake Inhibitors; Prazosin; Rats; Receptors, Adrenergic, alpha; Synaptosomes; Vas Deferens | 1990 |
Modulation of peripheral beta-1 and alpha-2 receptor sensitivities by the administration of the tricyclic antidepressant, imipramine, alone and in combination with alpha-2 antagonists to rats.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Dioxanes; Heart Rate; Hydroxydopamines; Idazoxan; Imipramine; In Vitro Techniques; Isoproterenol; Male; Oxidopamine; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Yohimbine | 1986 |
The alpha 2-adrenoceptor antagonists idazoxan and yohimbine increase rates of DRL responding in rats.
Topics: Adrenergic alpha-Agonists; Animals; Conditioning, Operant; Dextroamphetamine; Dioxanes; Dioxins; Idazoxan; Imipramine; Male; Mianserin; Rats; Rats, Inbred Strains; Reinforcement Schedule; Yohimbine | 1988 |
Strychnine-induced seizures in mice: the role of noradrenaline.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Disulfiram; Droxidopa; Idazoxan; Imipramine; Male; Mice; Pargyline; Phentolamine; Prazosin; Propranolol; Receptors, Adrenergic; Reserpine; Seizures; Strychnine | 1994 |
The involvement of noradrenaline, 5-hydroxytryptamine and acetylcholine in imipramine-induced seizures in mice.
Topics: 5-Hydroxytryptophan; Acetylcholine; alpha-Methyltyrosine; Animals; Atropine; Clonidine; Dioxanes; Droxidopa; Drug Synergism; Idazoxan; Imipramine; Male; Methyltyrosines; Mice; Norepinephrine; Pargyline; Phentolamine; Physostigmine; Prazosin; Reserpine; Seizures; Serotonin | 1993 |
Chronic imipramine treatment induces downregulation of alpha-2 receptors in rat's locus coeruleus and A2 region of the tractus solitarius.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Autoradiography; Densitometry; Dioxanes; Down-Regulation; Idazoxan; Imidazoles; Imipramine; Injections, Intraperitoneal; Locus Coeruleus; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Solitary Nucleus | 1996 |
Effects of long-term treatment with antidepressant drugs on proopiomelanocortin and neuropeptide Y mRNA expression in the hypothalamic arcuate nucleus of rats.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Arcuate Nucleus of Hypothalamus; Fluoxetine; Gene Expression; Idazoxan; Image Processing, Computer-Assisted; Imipramine; In Situ Hybridization; Male; Neuropeptide Y; Phenelzine; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors | 1996 |
Chronic imipramine treatment upregulates IR2-imidazoline receptive sites in rat brain.
Topics: Animals; Antidepressive Agents; Brain; Cell Membrane; Depression; Idazoxan; Imidazoline Receptors; Imipramine; Male; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Receptors, Drug; Tritium; Up-Regulation | 1997 |
Locus coeruleus neuronal activity and noradrenaline availability in the frontal cortex of rats chronically treated with imipramine: effect of alpha 2-adrenoceptor blockade.
Topics: Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug; Drug Synergism; Extracellular Space; Frontal Lobe; Idazoxan; Imipramine; Locus Coeruleus; Male; Neurons; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Time Factors | 1999 |
The α2C-adrenoceptor antagonist, ORM-10921, exerts antidepressant-like effects in the Flinders Sensitive Line rat.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Antidepressive Agents; Behavior, Animal; Benzofurans; Cognitive Dysfunction; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Idazoxan; Imipramine; Male; Motor Activity; Quinolizidines; Rats; Swimming | 2017 |