imipramine and hypericum

imipramine has been researched along with hypericum in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (25.81)18.2507
2000's22 (70.97)29.6817
2010's1 (3.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arnoldt, KH; Hübner, WD; Vorbach, EU2
Czekalla, J; Gastpar, M; Hübner, WD; Jäger, D1
Hafner, U; Müller, WE; Rolli, M; Schäfer, C1
Hiller, KO; Kohnen, R; Philipp, M1
de Beun, R; De Vry, J; Jentzsch, KR; Maurel, S; Schreiber, R1
Ernst, E; Stevinson, C1
Thornett, A1
Bhattacharya, SK; Jaiswal, AK; Kumar, V; Singh, PN1
Woelk, H1
Cornwall , PL1
Spira, JL1
Alkhenizan, A1
Völp, A1
Mannel, M; Rommelspacher, H; Siemanowitz, B1
Butterweck, V; Korte, B; Winterhoff, H1
De Montis, MG; Gambarana, C; Giachetti, D; Masi, F; Morazzoni, P; Rinaldi, M; Tolu, PL1
Brattström, A; Käufeler, R; Meier, B1
Bürgi, S; Honegger, UE; Kientsch, U; Probst, S; Ruedeberg, C1
Misane, I; Ogren, SO1
Butterweck, V; Herkenham, M; Winterhoff, H1
Böckers, T; Butterweck, V; Korte, B; Winterhoff, H; Wittkowski, W1
Bornstein, S; Ehrhart-Bornstein, M; Frost, P; Go, V; Heber, D; Hutson, C; Licinio, J; O'Kirwan, F; Wong, ML1
De Montis, MG; Gambarana, C; Giachetti, D; Grappi, S; Leggio, B; Nanni, G; Tolu, P; Usai, M1
Butterweck, V; Simbrey, K; Winterhoff, H1
Barros, HM; Ferigolo, M; Guilhermano, LG; Ortiz, L1
Elashoff, D; Hannestad, JP; Irizarry, KJ; Licinio, J; O'Kirwan, F; Wong, ML1
Goldstein, DS; Haertter, S; Jordan, J; Luft, FC; Schroeder, C; Stoeter, M; Tank, J1
Costentin, J; do Rego, JC; Janin, F; Naudin, B; Rates, S; Viana, A1
Costentin, J; Do Rego, JC; Müller, LG; Nunes, JM; Rates, SM; Stein, AC; Stolz, ED; Viana, AF; von Poser, GL1

Reviews

2 review(s) available for imipramine and hypericum

ArticleYear
Hypericum for depression. An update of the clinical evidence.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 9, Issue:6

    Topics: Amitriptyline; Antidepressive Agents; Depression; Humans; Hypericum; Imipramine; Phytotherapy; Plants, Medicinal; Randomized Controlled Trials as Topic

1999
Efficacy and tolerability of Ze 117 St. John's wort extract in comparison with placebo, imipramine and fluoxetine for the treatment of mild to moderate depression according to ICD-10. An overview.
    Pharmacopsychiatry, 2001, Volume: 34 Suppl 1

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depression; Fluoxetine; Humans; Hypericum; Imipramine; Placebos; Plant Extracts; Randomized Controlled Trials as Topic

2001

Trials

6 trial(s) available for imipramine and hypericum

ArticleYear
Effectiveness and tolerance of the hypericum extract LI 160 in comparison with imipramine: randomized double-blind study with 135 outpatients.
    Journal of geriatric psychiatry and neurology, 1994, Volume: 7 Suppl 1

    Topics: Adult; Aged; Antidepressive Agents; Depression; Double-Blind Method; Female; Humans; Hypericum; Imipramine; Male; Middle Aged; Perylene; Plant Extracts; Plants, Medicinal; Psychometrics; Quercetin; Severity of Illness Index; Xanthenes

1994
Efficacy and tolerability of St. John's wort extract LI 160 versus imipramine in patients with severe depressive episodes according to ICD-10.
    Pharmacopsychiatry, 1997, Volume: 30 Suppl 2

    Topics: Adult; Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Method; Female; Humans; Hypericum; Imipramine; Male; Middle Aged; Perylene; Plants, Medicinal; Psychiatric Status Rating Scales; Quercetin; Xanthenes

1997
The effect of hypericum extract on cardiac conduction as seen in the electrocardiogram compared to that of imipramine.
    Pharmacopsychiatry, 1997, Volume: 30 Suppl 2

    Topics: Adult; Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Method; Electrocardiography; Female; Heart Conduction System; Humans; Hypericum; Imipramine; Male; Middle Aged; Perylene; Plants, Medicinal; Psychiatric Status Rating Scales; Quercetin; Xanthenes

1997
Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks.
    BMJ (Clinical research ed.), 1999, Dec-11, Volume: 319, Issue:7224

    Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Method; Female; Humans; Hypericum; Imipramine; Male; Middle Aged; Patient Compliance; Phytotherapy; Plants, Medicinal; Quality of Life; Treatment Outcome

1999
Comparison of St John's wort and imipramine for treating depression: randomised controlled trial.
    BMJ (Clinical research ed.), 2000, Sep-02, Volume: 321, Issue:7260

    Topics: Adult; Antidepressive Agents, Tricyclic; Depression; Double-Blind Method; Female; Humans; Hypericum; Imipramine; Male; Middle Aged; Phytotherapy; Plants, Medicinal; Psychiatric Status Rating Scales

2000
Influence of St John's wort on catecholamine turnover and cardiovascular regulation in humans.
    Clinical pharmacology and therapeutics, 2004, Volume: 76, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Uptake Inhibitors; Adult; Anthracenes; Autonomic Nervous System; Cardiovascular Physiological Phenomena; Catecholamines; Cross-Over Studies; Double-Blind Method; Female; Hemodynamics; Humans; Hypericum; Imipramine; Male; Methoxyhydroxyphenylglycol; Nitric Oxide Donors; Nitroprusside; Norepinephrine; Perylene; Posture; Supine Position

2004

Other Studies

23 other study(ies) available for imipramine and hypericum

ArticleYear
Effects of hypericum extract (LI 160) in biochemical models of antidepressant activity.
    Pharmacopsychiatry, 1997, Volume: 30 Suppl 2

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Brain; Depression; Dopamine Uptake Inhibitors; Female; Hypericum; Imipramine; Mice; Monoamine Oxidase; Perylene; Plants, Medicinal; Prefrontal Cortex; Quercetin; Rats; Receptors, Adrenergic, beta; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Synaptosomes; Xanthenes

1997
Comparison of hypericum extracts with imipramine and fluoxetine in animal models of depression and alcoholism.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 9, Issue:6

    Topics: Alcoholism; Animals; Antidepressive Agents; Depression; Drug Evaluation, Preclinical; Female; Fluoxetine; Hypericum; Imipramine; Male; Phytotherapy; Plants, Medicinal; Rats; Rats, Wistar

1999
A boost for St. John's Wort?
    Health news (Waltham, Mass.), 2000, Volume: 6, Issue:2

    Topics: Antidepressive Agents, Tricyclic; Depression; Drug Interactions; Humans; Hypericum; Imipramine; Phytotherapy; Plants, Medicinal

2000
Use of hypericum as antidepressant. Valid measure of antidepressant efficacy in primary care is needed.
    BMJ (Clinical research ed.), 2000, Apr-22, Volume: 320, Issue:7242

    Topics: Antidepressive Agents, Tricyclic; Depression; Humans; Hypericum; Imipramine; Phytotherapy; Placebos; Plants, Medicinal; Treatment Outcome

2000
Antidepressant activity of Indian Hypericum perforatum Linn in rodents.
    Indian journal of experimental biology, 1999, Volume: 37, Issue:12

    Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Female; Hypericum; Imipramine; Male; Mice; Plant Extracts; Plants, Medicinal; Rats

1999
Comparison of St John's Wort and imipramine. Remission is important outcome.
    BMJ (Clinical research ed.), 2001, Feb-24, Volume: 322, Issue:7284

    Topics: Antidepressive Agents, Tricyclic; Depressive Disorder; Humans; Hypericum; Imipramine; Phytotherapy; Plants, Medicinal; Remission Induction

2001
Comparison of St John's Wort and imipramine. Study design casts doubt on value of St John's wort in treating depression.
    BMJ (Clinical research ed.), 2001, Feb-24, Volume: 322, Issue:7284

    Topics: Antidepressive Agents, Tricyclic; Depressive Disorder; Humans; Hypericum; Imipramine; Phytotherapy; Plants, Medicinal; Research Design

2001
Comparison of St John's Wort and imipramine. Finding must be treated with caution.
    BMJ (Clinical research ed.), 2001, Feb-24, Volume: 322, Issue:7284

    Topics: Antidepressive Agents, Tricyclic; Depressive Disorder; Humans; Hypericum; Imipramine; Phytotherapy; Plants, Medicinal; Research Design

2001
Comparison of St John's Wort and imipramine. Sensitivity of assay is questionable.
    BMJ (Clinical research ed.), 2001, Feb-24, Volume: 322, Issue:7284

    Topics: Antidepressive Agents, Tricyclic; Depressive Disorder; Humans; Hypericum; Imipramine; Phytotherapy; Plants, Medicinal; Research Design; Sensitivity and Specificity; Statistics as Topic

2001
Acute and chronic actions of a dry methanolic extract of Hypericum perforatum and a hyperforin-rich extract on dopaminergic and serotonergic neurones in rat nucleus accumbens.
    Pharmacopsychiatry, 2001, Volume: 34 Suppl 1

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Bridged Bicyclo Compounds; Dopamine; Dose-Response Relationship, Drug; Hypericum; Imipramine; Male; Methanol; Microdialysis; Neurons; Nucleus Accumbens; Phloroglucinol; Plant Extracts; Rats; Rats, Inbred Strains; Serotonin; Solvents; Terpenes

2001
Pharmacological and endocrine effects of Hypericum perforatum and hypericin after repeated treatment.
    Pharmacopsychiatry, 2001, Volume: 34 Suppl 1

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Anthracenes; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antioxidants; Biflavonoids; Catechin; Corticosterone; Endocrine System; Exploratory Behavior; Hypericum; Imipramine; Luteinizing Hormone; Male; Organ Size; Perylene; Pituitary Gland; Plant Extracts; Proanthocyanidins; Rats; Rats, Inbred Strains; Seminal Vesicles; Swimming

2001
A study of the antidepressant activity of Hypericum perforatum on animal models.
    Pharmacopsychiatry, 2001, Volume: 34 Suppl 1

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bridged Bicyclo Compounds; Chronic Disease; Depression; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Electroshock; Fluoxetine; Hypericum; Imipramine; Microdialysis; Phloroglucinol; Plant Extracts; Rats; Stress, Physiological; Terpenes

2001
St. John's wort extract Ze 117 (Hypericum perforatum) inhibits norepinephrine and serotonin uptake into rat brain slices and reduces 3-adrenoceptor numbers on cultured rat brain cells.
    Pharmacopsychiatry, 2001, Volume: 34 Suppl 1

    Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Astrocytoma; Cerebral Cortex; Desipramine; Hypericum; Imipramine; Norepinephrine; Organ Culture Techniques; Plant Extracts; Rats; Receptors, Adrenergic, beta; Serotonin; Tumor Cells, Cultured

2001
Effects of Hypericum perforatum (St. John's wort) on passive avoidance in the rat: evaluation of potential neurochemical mechanisms underlying its antidepressant activity.
    Pharmacopsychiatry, 2001, Volume: 34 Suppl 1

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Avoidance Learning; Behavior, Animal; Brain Chemistry; Desipramine; Hypericum; Imipramine; Male; Muscarinic Antagonists; Norepinephrine; Paroxetine; Plant Extracts; Rats; Rats, Sprague-Dawley; Scopolamine; Serotonin

2001
St John's wort, hypericin, and imipramine: a comparative analysis of mRNA levels in brain areas involved in HPA axis control following short-term and long-term administration in normal and stressed rats.
    Molecular psychiatry, 2001, Volume: 6, Issue:5

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Anthracenes; Antidepressive Agents; Arginine Vasopressin; Brain; Brain-Derived Neurotrophic Factor; Corticosterone; Corticotropin-Releasing Hormone; Cyclic AMP Response Element-Binding Protein; Drug Administration Schedule; Glutamate Decarboxylase; Hippocampus; Hypericum; Hypothalamo-Hypophyseal System; Imipramine; In Situ Hybridization; Isoenzymes; Locus Coeruleus; Male; Paraventricular Hypothalamic Nucleus; Perylene; Pituitary Gland; Plants, Medicinal; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reference Values; Restraint, Physical; RNA, Messenger; Stress, Psychological; Transcription, Genetic; Tyrosine 3-Monooxygenase

2001
Long-term effects of St. John's wort and hypericin on monoamine levels in rat hypothalamus and hippocampus.
    Brain research, 2002, Mar-15, Volume: 930, Issue:1-2

    Topics: Animals; Anthracenes; Antidepressive Agents, Tricyclic; Biogenic Monoamines; Dopamine; Hippocampus; Hypericum; Hypothalamus; Imipramine; Kinetics; Male; Norepinephrine; Perylene; Rats; Serotonin

2002
The prototypic antidepressant drug, imipramine, but not Hypericum perforatum (St. John's Wort), reduces HPA-axis function in the rat.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2003, Volume: 35, Issue:10

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Corticosterone; Hypericum; Hypothalamus; Imipramine; Male; Pituitary Gland; Plant Extracts; Rats; Rats, Sprague-Dawley

2003
Hypericum perforatum subspecies angustifolium shows a protective activity on the consequences of unavoidable stress exposure at lower doses than Hypericum perforatum perforatum.
    Pharmacopsychiatry, 2003, Volume: 36, Issue:6

    Topics: Animals; Antidepressive Agents; Bridged Bicyclo Compounds; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Hypericum; Imipramine; Male; Phloroglucinol; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Stress, Psychological; Terpenes

2003
Extracts of St. John's wort and various constituents affect beta-adrenergic binding in rat frontal cortex.
    Life sciences, 2004, Jan-09, Volume: 74, Issue:8

    Topics: Animals; Anthracenes; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bridged Bicyclo Compounds; Cell Membrane; Fluoxetine; Frontal Lobe; Hypericum; Imipramine; Male; Perylene; Phloroglucinol; Plant Extracts; Quercetin; Radioligand Assay; Rats; Receptors, Adrenergic, beta; Terpenes

2004
Commercially available Hypericum perforatum extracts do not decrease immobility of rats in the forced swimming test.
    Progress in neuro-psychopharmacology & biological psychiatry, 2004, Volume: 28, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Hypericum; Imipramine; Male; Motor Activity; Plant Extracts; Rats; Rats, Wistar; Swimming

2004
St John's wort and imipramine-induced gene expression profiles identify cellular functions relevant to antidepressant action and novel pharmacogenetic candidates for the phenotype of antidepressant treatment response.
    Molecular psychiatry, 2004, Volume: 9, Issue:3

    Topics: Antidepressive Agents; Enzymes; Gene Expression Profiling; Gene Expression Regulation; Humans; Hypericum; Imipramine; Models, Genetic; Oligonucleotide Array Sequence Analysis; Phenotype; Plant Extracts; Proteins; Transcription, Genetic

2004
Effects of acute or 3-day treatments of Hypericum caprifoliatum Cham. & Schltdt. (Guttiferae) extract or of two established antidepressants on basal and stress-induced increase in serum and brain corticosterone levels.
    Journal of psychopharmacology (Oxford, England), 2008, Volume: 22, Issue:6

    Topics: Animals; Antidepressive Agents; Bupropion; Cerebral Cortex; Corticosterone; Cyclohexanes; Drug Administration Schedule; Humans; Hypericum; Imipramine; Mice; Mice, Inbred Strains; Motor Activity; Plant Extracts; Restraint, Physical; Swimming

2008
Uliginosin B, a phloroglucinol derivative from Hypericum polyanthemum: a promising new molecular pattern for the development of antidepressant drugs.
    Behavioural brain research, 2012, Mar-01, Volume: 228, Issue:1

    Topics: Animals; Antidepressive Agents; Benzazepines; Biogenic Monoamines; Bupropion; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fenclonine; Fluoxetine; Hypericum; Imipramine; Immobility Response, Tonic; Locomotion; Male; Mice; Mice, Inbred Strains; Phloroglucinol; Plant Extracts; Prazosin; Rats; Rats, Wistar; Receptors, Catecholamine; Sulpiride; Vesicular Monoamine Transport Proteins; Yohimbine

2012