Compounds > imipramine

imipramine and hydralazine

imipramine has been researched along with hydralazine in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (33.33)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (41.67)	29.6817
2010's	3 (25.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Balkovetz, DF; Ganapathy, V; Leibach, FH; Mahesh, VB; Tiruppathi, C	1
Medzihradsky, F; Nandhasri, PS	1
Greengard, P; Quinn, GP; Reid, MB	1
Bucher, K; Floersheim, GL	1

Reviews

1 review(s) available for imipramine and hydralazine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

11 other study(ies) available for imipramine and hydralazine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Evidence for an imipramine-sensitive serotonin transporter in human placental brush-border membranes. The Journal of biological chemistry, 1989, Feb-05, Volume: 264, Issue:4 Topics: Carrier Proteins; Cations, Monovalent; Desipramine; Female; Humans; Hydralazine; Imipramine; Kinetics; Microvilli; Placenta; Potassium Chloride; Pregnancy; Reserpine; Serotonin; Sodium Chloride	1989
Effects of some analgesics and antidepressants on the (Na + + K + )-adenosine triphosphatase from cortices of brain and kidney. Biochemical pharmacology, 1972, Aug-01, Volume: 21, Issue:15 Topics: Adenosine Triphosphatases; Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cattle; Cerebral Cortex; Chlorpromazine; Cyclazocine; Desipramine; Dose-Response Relationship, Drug; Hydralazine; Imipramine; In Vitro Techniques; Kidney; Kidney Cortex; Pentazocine; Phenazocine; Phenelzine; Potassium; Sodium; Tranylcypromine	1972
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism. Molecular pharmacology, 1966, Volume: 2, Issue:4 Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine	1966
Effects of thyroxine, oxyphenbutazone and imipramine on an inflammatory graft-versus-host reaction in chicks. Agents and actions, 1972, Volume: 2, Issue:4 Topics: Animals; Atropine; Chickens; Gold; Graft vs Host Reaction; Hydralazine; Imipramine; Inflammation; Lymphocyte Transfusion; Male; Methysergide; Oxyphenbutazone; Peptides; Thyroxine; Transplantation, Homologous	1972