imipramine and hexobarbital

imipramine has been researched along with hexobarbital in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	31 (79.49)	18.7374
1990's	2 (5.13)	18.2507
2000's	5 (12.82)	29.6817
2010's	1 (2.56)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Caron, G; Ermondi, G	1
Abraham, MH; Acree, WE; Ibrahim, A	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Bhattacharya, SK	1
Kästner, I	1
Ghoneim, MT; Mahfouz, M; Makar, AB	1
Chistiakov, VV; Lavretskaia, EF; Libinzon, RE; Mal'dov, DG; Ratnikov, LA	1
Bobkiewicz, T; Chodera, A; Nowakowska, E; Okulicz-Kozaryn, I	1
Chen, XH; de Zeeuw, RA; Ensing, K; Franke, JP; Temmink, A	1
Daniel, W; Netter, KJ	1
Kimishima, K; Ogura, C	1
Greengard, P; Quinn, GP; Reid, MB	1
Gigon, PL; Gillette, JR; Gram, TE	2
Gillette, JR; Hamrick, M; Sasame, H; Stripp, B; Zampaglione, N	1
Gillette, JR; Hamrick, M; Stripp, B; Zampaglione, N	1
Honma, T; Inaba, S; Kitagawa, S; Ono, K; Sasajima, K; Yamamoto, H	1
Doi, T; Kojima, S; Tsujimoto, A	1
O'Malley, K; Sawyer, PR; Stevenson, IH	1
Jori, A; Pescador, R; Pugliatti, C	1
Di Salle, E; Jori, A; Santini, V	1
Herr, F; Voith, K	1
Mészáros, C; Pálosi, E; Szporny, L	1
Nieschulz, O	1
Katz, MH; Krop, S; Yen, HC	1
Kakemi, K; Kimura, T; Konishi, R; Sezaki, H	1
Bijlani, JC; Kekre, MS; Sachdev, KS	1
Culp, HW; Gibson, WR; Marshall, FJ; McMahon, RE; Miller, WM; Mills, J	1
Eble, JN; Shriver, KL; Trepanier, DL	1
Burger, A; Siuda, JF	1
Haas, H; Jantos, W	1
Shillito, EE	1
CHIESARA, E; KATO, R; VASSANELLI, P	1
ENDROECZI, E; KORANYI, L; LISSAK, K	1
MCCANCE, I	1
BUECH, O; KUNZ, HA; MORPURGO, C; STENGER, EG; THEOBALD, W; WILHELMI, G	1

Other Studies

39 other study(ies) available for imipramine and hexobarbital

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Imipramine induced potentiation of hexobarbitone hypnosis in rat: role of serotonin. Indian journal of experimental biology, 1978, Volume: 16, Issue:3 Topics: Animals; Drug Synergism; Female; Hexobarbital; Imipramine; Male; Rats; Serotonin Antagonists; Sleep	1978
[Experimental imipramine intoxication in the albino rat]. Die Pharmazie, 1978, Volume: 33, Issue:9 Topics: Animals; Diazepam; Electroencephalography; Hexobarbital; Imipramine; Male; Rats; Time Factors	1978
Effect of some central nervous system acting drugs on rat brain and liver monoamine oxidase activity. Agents and actions, 1977, Volume: 7, Issue:2 Topics: Alcoholic Beverages; Animals; Brain; Central Nervous System; Chloralose; Diazepam; Ethanol; Hexobarbital; Imipramine; Liver; Male; Monoamine Oxidase; Rats	1977
[Interaction of psychotropic and anticonvulsive drugs]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1976, Volume: 76, Issue:8 Topics: Aminopyrine; Animals; Chlordiazepoxide; Chlorpromazine; Cytochrome P-450 Enzyme System; DNA; Hexobarbital; Imipramine; Liver; Male; Microsomes, Liver; Phenobarbital; Proteins; Rats; RNA	1976
Influence of tricyclic antidepressant drugs on experimental arterial hypertension. Archivum immunologiae et therapiae experimentalis, 1975, Volume: 23, Issue:4 Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Female; Hexobarbital; Hypertension; Imipramine; Kidney; Male; Nephrectomy; Nortriptyline; Opipramol; Rats	1975
Application of Empore C-8 extraction disks for screening urine in systematic toxicological analysis. Journal of forensic sciences, 1992, Volume: 37, Issue:2 Topics: Barbiturates; Codeine; Dexetimide; Filtration; Hexobarbital; Humans; Imipramine; Methamphetamine; Molecular Structure; Nitrazepam; Prazepam; Pyrilamine	1992
Alteration of cytochrome P-450 by prolonged administration of imipramine and/or lithium to rats. Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 342, Issue:2 Topics: Animals; Carbamazepine; Cytochrome P-450 Enzyme System; Desipramine; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Hexobarbital; Imipramine; Isoenzymes; Lithium; Liver; Male; Metyrapone; Rats; Rats, Inbred Strains	1990
Central nervous actions and screening methods of antidepressants. Folia psychiatrica et neurologica japonica, 1972, Volume: 26, Issue:4 Topics: Acetylcholine; Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Biogenic Amines; Blood Pressure; Brain Chemistry; Central Nervous System; Diazepam; Electroshock; Ethanol; Hexobarbital; Hypertension; Hypothermia, Induced; Imipramine; Iproniazid; Methamphetamine; Mice; Nialamide; Physostigmine; Piperidines; Reserpine; Tremorine	1972
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism. Molecular pharmacology, 1966, Volume: 2, Issue:4 Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine	1966
Effect of drug substrates on the reduction of hepatic microsomal cytochrome P-450 by NADPH. Biochemical and biophysical research communications, 1968, May-23, Volume: 31, Issue:4 Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; Kinetics; Liver; Male; Microsomes; Morphine; NADP; Niacinamide; Oxidation-Reduction; Pigments, Biological; Proadifen; Rats; Sex Factors; Spectrophotometry; Transferases	1968
Studies on the rate of reduction of hepatic microsomal cytochrome P-450 by reduced nicotinamide adenine dinucleotide phosphate: effect of drug substrates. Molecular pharmacology, 1969, Volume: 5, Issue:2 Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Proadifen; Rats; Sex Factors; Spectrophotometry; Time Factors; Valerates	1969
Studies of the stoichiometric relationships between the oxidation of drugs and the oxidation of reduced pyridine nucleotides by liver microsomal enzymes. Chemico-biological interactions, 1971, Volume: 3, Issue:4 Topics: Adenine Nucleotides; Aminopyrine; Cytochromes; Hexobarbital; Imipramine; Microsomes, Liver; Morphinans; NADP; Nucleotides; Oxidation-Reduction; Pharmaceutical Preparations; Pyridines	1971
An approach measurement of the stoichiometric relationship between hepatic microsomal drug metabolism and the oxidation of reduced nicotinamide adenine dinucleotide phosphate. Molecular pharmacology, 1972, Volume: 8, Issue:2 Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Benzyl Compounds; Chlorine; Dealkylation; Ethylamines; Hexobarbital; Imipramine; Male; Methylamines; Microsomes, Liver; Morphine; NADP; Oxidation-Reduction; Pharmaceutical Preparations; Rats	1972
Synthesis and preliminary pharmacology of a novel butyrophenone derivative, ID-4708. Arzneimittel-Forschung, 1974, Volume: 24, Issue:9 Topics: Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Butyrophenones; Catalepsy; Cats; Chlorpromazine; Drug Evaluation, Preclinical; Drug Synergism; Electroencephalography; Epinephrine; Haloperidol; Hexobarbital; Humans; Hydrocarbons, Fluorinated; Imipramine; Lethal Dose 50; Male; Methamphetamine; Mice; Motor Activity; Pain; Piperidines; Rats; Trifluperidol	1974
Potent inhibitory action of pilocarpine on hepatic drug metabolism. Japanese journal of pharmacology, 1972, Volume: 22, Issue:5 Topics: Aniline Compounds; Animals; Depression, Chemical; Ethylamines; Glucosephosphate Dehydrogenase; Hexobarbital; Imipramine; In Vitro Techniques; Liver; Male; Nicotine; Phenols; Pilocarpine; Proadifen; Rabbits; Spectrophotometry; Tritium	1972
Proceedings: Effect of tricyclic antidepressants on drug metabolism. British journal of pharmacology, 1972, Volume: 44, Issue:2 Topics: Adult; Amitriptyline; Animals; Antidepressive Agents; Antipyrine; Desipramine; Dibenzazepines; Female; Half-Life; Hexobarbital; Humans; Imipramine; Liver; Male; Nortriptyline; Rats	1972
Rat strain differences in the activity of hepatic microsomal enzymes. Biochemical pharmacology, 1971, Volume: 20, Issue:10 Topics: Aminopyrine; Amphetamine; Animals; Anisoles; Biotransformation; Brain; Dealkylation; Ethers; Female; Hexobarbital; Imipramine; Male; Microsomes, Liver; Nitro Compounds; Phenols; Rats; Species Specificity; Zoxazolamine	1971
Daily rhythmic variation and liver drug metabolism in rats. Biochemical pharmacology, 1971, Volume: 20, Issue:11 Topics: Aminopyrine; Animals; Anisoles; Circadian Rhythm; Corticosterone; Ethers; Female; Hexobarbital; Imipramine; Liver; Microsomes, Liver; Nitro Compounds; Phenols; Rats; Rats, Inbred Strains	1971
Psychopharmacological evaluation of a new antidepressant: butriptyline. Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 182, Issue:2 Topics: Acetylcholine; Amphetamine; Animals; Antidepressive Agents; Atropine; Body Temperature; Consummatory Behavior; Depression, Chemical; Dibenzocycloheptenes; Drug Antagonism; Drug Synergism; Escape Reaction; Ethanol; Guinea Pigs; Hexobarbital; Histamine; Ileum; Imipramine; Male; Mice; Promethazine; Rats; Reserpine; Tremorine	1969
Pharmacological studies with N-3,4,5-trimethoxybenzoyl-heptamethylene imine (N-1157), a new antidepressant agent. Arzneimittel-Forschung, 1969, Volume: 19, Issue:11 Topics: Amphetamine; Animals; Antidepressive Agents; Ataxia; Blood Pressure; Body Temperature; Catalepsy; Cats; Depression, Chemical; Dogs; Drug Synergism; Electrocardiography; Escape Reaction; Female; Hexobarbital; Humans; Imipramine; In Vitro Techniques; Liver; Male; Mice; Monoamine Oxidase Inhibitors; Nialamide; Norepinephrine; Orientation; Rabbits; Rats; Reserpine; Respiration; Stimulation, Chemical	1969
[Pharmacology of the active substances in betel. 3. Experiments with arecaidine]. Arzneimittel-Forschung, 1970, Volume: 20, Issue:2 Topics: Animals; Areca; Behavior, Animal; Bile; Blood Glucose; Blood Pressure; Caffeine; Chlorpromazine; Depression, Chemical; Diuresis; Dogs; Drug Synergism; Efficiency; Glutamates; Hexobarbital; Imipramine; Learning; Mice; Nicotinic Acids; Parasympathomimetics; Perception; Phenothiazines; Plant Extracts; Plants, Medicinal; Psychopharmacology; Rats; Reserpine; Stimulation, Chemical	1970
Effects of various drugs on 3,4-dihydroxyphenylalanine (DL-DOPA)-induced excitation (agressive behavior) in mice. Toxicology and applied pharmacology, 1970, Volume: 17, Issue:3 Topics: Aggression; Animals; Antidepressive Agents; Autonomic Agents; Behavior, Animal; Bretylium Compounds; Chlordiazepoxide; Chlorpromazine; Diazepam; Dihydroxyphenylalanine; Drug Antagonism; Haloperidol; Hexobarbital; Humans; Imipramine; Iproniazid; Male; Mice; Morphine; Oxazepam; Reserpine; Tranquilizing Agents; Tranylcypromine; Trifluoperazine	1970
Inhibitory mechanism of imipramine on barbiturate metabolism in rat liver. Chemical & pharmaceutical bulletin, 1971, Volume: 19, Issue:7 Topics: Animals; Barbiturates; Depression, Chemical; Desipramine; Hexobarbital; Imipramine; In Vitro Techniques; Liver; Male; Rats; Secobarbital; Thiopental	1971
Potentiation of hexobarbitone sleeping time by imipramine. Its possible mechanism. Indian journal of medical sciences, 1968, Volume: 22, Issue:3 Topics: Animals; Chlorpromazine; Drug Synergism; Female; Hexobarbital; Imipramine; Male; Mice; Nialamide; Sleep	1968
Demethylation studies. VI. The inhibition of hepatic microsomal oxygenation by 2,4-dichloro(6-phenylphenoxy)ethylamine and related compounds. Journal of medicinal chemistry, 1969, Volume: 12, Issue:2 Topics: Aminopyrine; Amitriptyline; Animals; Butylamines; Carbamates; Carbon Isotopes; Dextropropoxyphene; Dogs; Ethylamines; Hexobarbital; Imipramine; In Vitro Techniques; Liver; Male; Mice; Microsomes; Morphinans; Naphthalenes; Nitriles; Phenethylamines; Phenobarbital; Propylamines; Rats	1969
Aryl-substituted triazines with antidepressant activity. Journal of medicinal chemistry, 1969, Volume: 12, Issue:2 Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Dextroamphetamine; Drug Synergism; Electroshock; Hexobarbital; Imipramine; Mice; Reserpine; Sleep; Triazines	1969
o,o'-Disubstituted phenylcyclopropylamines. Journal of medicinal chemistry, 1969, Volume: 12, Issue:2 Topics: Amphetamine; Animals; Blepharoptosis; Hexobarbital; Imipramine; Mice; Motor Activity; Propylamines; Reserpine; Salivation; Seizures; Sleep; Tryptamines	1969
[Modification of central mechanisms of action by anticholinergics]. Arzneimittel-Forschung, 1969, Volume: 19, Issue:1 Topics: Aggression; Amphetamine; Animals; Apomorphine; Atropine; Biperiden; Bridged-Ring Compounds; Central Nervous System; Chlorpromazine; Depression, Chemical; Drug Synergism; Esters; Female; Hexobarbital; Humans; Imipramine; Male; Mice; Morphine; Nicotine; Parasympatholytics; Pentylenetetrazole; Perphenazine; Rats; Stimulation, Chemical; Strychnine; Tremorine	1969
A method for recording the effect of drugs on the activity of small mammals over long periods of time. British journal of pharmacology and chemotherapy, 1966, Volume: 26, Issue:1 Topics: Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Chlordiazepoxide; Chlorpromazine; Desipramine; Hexobarbital; Hypnotics and Sedatives; Imipramine; Iproniazid; Meprobamate; Mice; Reserpine	1966
Mechanism of potentiation of barbiturates and mepbrobamate actions by imipramine. Biochemical pharmacology, 1963, Volume: 12 Topics: Barbiturates; Chloral Hydrate; Hexobarbital; Imipramine; Meprobamate; Muscle Relaxants, Central; Pentobarbital	1963
HYPERMOTILITY EVOKED BY LESIONS OF THE SEPTUM AND ANTERIOR HYPOTHALAMUS. Acta physiologica Academiae Scientiarum Hungaricae, 1963, Volume: 23 Topics: Aminopyrine; Amygdala; Atropine; Body Temperature; Caudate Nucleus; Cerebral Ventricles; Chlorpromazine; Electrocoagulation; Ephedrine; Hexobarbital; Hippocampus; Hypothalamus; Hypothalamus, Anterior; Imipramine; Iproniazid; Metabolism; Morphine; Movement Disorders; Physostigmine; Rats; Research; Reserpine; Scopolamine	1963
STUDIES OF POTENTIATION OF HEXOBARBITONE INFUSED INTRAVENOUSLY. Archives internationales de pharmacodynamie et de therapie, 1964, Mar-01, Volume: 148 Topics: Anesthesia; Anesthesia, Intravenous; Anti-Anxiety Agents; Anticonvulsants; Atropine; Benactyzine; Carbamates; Carisoprodol; Chlorpromazine; Chlorprothixene; Hexobarbital; Hydroxyzine; Hypnotics and Sedatives; Imipramine; Infusions, Parenteral; Meprobamate; Mice; Pharmacology; Phenothiazines; Promazine; Research; Serotonin; Thalidomide; Tranquilizing Agents	1964
[COMPARATIVE PHARMACOLOGICAL INVESTIGATIONS WITH TOFRANIL, PERTOFRAN AND INSIDON]. Archives internationales de pharmacodynamie et de therapie, 1964, Apr-01, Volume: 148 Topics: Acetylcholine; Amphetamine; Amphetamines; Anesthetics; Animals; Antidepressive Agents; Catatonia; Cats; Chlorpromazine; Cricetinae; Desipramine; Dextroamphetamine; Epinephrine; Ethanol; Guinea Pigs; Hexobarbital; Histamine; Imipramine; Mice; Neuromuscular Junction; Norepinephrine; Opipramol; Orientation; Pharmacology; Rats; Research; Reserpine; Serotonin; Tetrabenazine; Tremor; Tyramine	1964