imipramine has been researched along with gamma-aminobutyric acid in 54 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 26 (48.15) | 18.7374 |
1990's | 7 (12.96) | 18.2507 |
2000's | 8 (14.81) | 29.6817 |
2010's | 13 (24.07) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Ali, FE; Bondinell, WE; Dandridge, PA; Frazee, JS; Garvey, E; Girard, GR; Kaiser, C; Ku, TW; Lafferty, JJ; Moonsammy, GI | 1 |
Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM | 1 |
Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG | 1 |
Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K | 1 |
Anzini, M; Brogi, S; Butini, S; Campiani, G; Cappelli, A; Caselli, G; Castriconi, F; Gemma, S; Giordani, A; Giorgi, G; Giuliani, G; Lanza, M; Letari, O; Makovec, F; Manini, M; Mennuni, L; Valenti, S | 1 |
Belyakov, S; Dambrova, M; Kazoka, H; Kuznecovs, J; Lebedev, A; Liepinsh, E; Mishnev, A; Orlova, N; Ponomaryov, Y; Vavers, E; Veinberg, G; Vikainis, S; Vilskersts, R; Vorona, M; Zvejniece, L | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E | 1 |
Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E | 1 |
Glaeser, BS; Hare, TA; Oleweiler, DB; Vogel, WH | 1 |
Greenlee, D; Olsen, RW; Ticku, MK; Van Ness, PC | 1 |
Kutin, GV; Kutin, VP | 1 |
Bayless, JD; Lamar, EE; Olsen, RW | 1 |
Ban, M; Lee, JM; Olsen, RW | 1 |
Maĭsov, NI; Raevskiĭ, KS | 1 |
Baker, GB; Greenshaw, AJ; Martin, IL; McKenna, KF; McManus, DJ | 1 |
Iovino, M; Maj, M; Monteleone, P; Steardo, L | 1 |
Nitsch, C; von Metzler, A | 1 |
Anami, K; Maruyama, Y; Sakamori, M; Setoguchi, M; Takehara, S | 1 |
Ikeda, M; Knapp, RJ; Malatynska, E; Yamamura, HI | 1 |
Corda, MG; Fernandez Teruel, A; Longoni, B | 1 |
Ballejo, G; Calixto, JB; Strobel, GH | 1 |
Gianutsos, G; Suzdak, PD | 3 |
Bartholini, G; Depoortere, H; Lloyd, KG; Sanger, D; Zivkovic, B | 1 |
Arbilla, S; Bartholini, G; Claustre, Y; Dedek, J; Dennis, T; Langer, SZ; Lloyd, KG; Scatton, B; Zivkovic, B | 1 |
Anami, K; Fukuda, T; Maruyama, Y; Morimoto, Y; Setoguchi, M; Usa, T | 1 |
Danti, S; Martin, P; Poncelet, M; Simon, P; Soubrié, P | 1 |
Kryzhanovskiĭ, GN; Maĭsov, NI; Nikushkin, EV | 1 |
Wenk, GL | 1 |
Berrettini, WH; Gershon, ES; Goldin, LR; Nurnberger, JI | 1 |
Petty, F; Sherman, AD | 1 |
Bartholini, G; Broekkamp, C; Depoortere, H; Fournier, V; Lloyd, KG; Morselli, PL; Scatton, B; Worms, P; Zivkovic, B | 1 |
Blier, P; de Montigny, C; Tardif, D | 1 |
Avdulov, NA; Maĭsov, NI | 1 |
Alkon, DL; Anderson, MJ; Collin, C; Fass, DM; Kapetanovic, IM; Kuzirian, AJ; Matzel, LD; Nelson, TJ; Rogers, DF | 1 |
Halonen, T; Jolkkonen, J; Lepola, U; Riekkinen, P; Rimón, R | 1 |
Cooper, TB; Costa, E; Guidotti, A; Uzunov, DP | 1 |
Vamvakides, A | 1 |
Brand, L; Harvey, BH; Heenop, M; Jonker, LP; Stein, DJ | 1 |
Bruins Slot, LA; Colpaert, FC; Koek, W; Ribet, JP; Tarayre, JP | 1 |
Assié, MB; Bardin, L; Carilla-Durand, E; Colpaert, FC; Cosi, C; Koek, W; Pauwels, PJ; Tarayre, JP; Vacher, B; Wiesenfeld-Hallin, Z; Xu, XJ | 1 |
Azarmina, P; Rostami, P; Shafaghi, B; Shamsi, T; Zarrindast, MR | 1 |
Bach, FW; Jensen, TS; Rasmussen, PV; Sindrup, SH | 1 |
Borsook, D; Hama, AT | 1 |
Bansal, V; Hota, D; Pattanaik, S | 1 |
Arai, YC; Arakawa, M; Hayashi, R; Kinoshita, A; Kobayashi, K; Kondo, M; Matsubara, S; Matsubara, T; Nishida, K; Nishihara, M; Shimo, K; Suetomi, K; Suzuki, C; Tohyama, Y; Ushida, T | 1 |
Bacci, A; Méndez, P; Pazienti, A; Szabó, G | 1 |
Holland, MG; Marraffa, JM; Ryzewski, M; Sullivan, RW | 1 |
El Zahaf, NA; Salem Elhwuegi, A | 1 |
Li, J; Miao, Z; Qian, X; Ren, L; Sun, M; Xu, X; Zhai, L | 1 |
Harada, S; Matsuura, W; Tokuyama, S | 1 |
Barbosa-Filho, JM; Chaves, EMC; Dantas, LP; Honório-Júnior, JER; Lúcio, ASSC; Monteiro, VS; Nonato, DTT; Patrocínio, MCA; Sousa, CNS; Vasconcelos, SMM; Viana, GSB | 1 |
2 review(s) available for imipramine and gamma-aminobutyric acid
Article | Year |
---|---|
The role of receptor binding in drug discovery.
Topics: Animals; Drug Design; Humans; Receptors, Drug | 1993 |
Genetic factors in affective illness.
Topics: ABO Blood-Group System; Blood Platelets; Cholinergic Fibers; Diseases in Twins; Female; gamma-Aminobutyric Acid; Genetic Linkage; Genetic Markers; HLA Antigens; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Imipramine; Mood Disorders; Pregnancy; Sleep, REM; Twins, Monozygotic; Tyramine; X Chromosome | 1984 |
4 trial(s) available for imipramine and gamma-aminobutyric acid
Article | Year |
---|---|
The potential use of GABA agonists in psychiatric disorders: evidence from studies with progabide in animal models and clinical trials.
Topics: Adjustment Disorders; Animals; Anticonvulsants; Biogenic Amines; Brain; Clinical Trials as Topic; Corpus Striatum; Depressive Disorder; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Humans; Imipramine; Limbic System; Neurons; Rats | 1983 |
Cerebrospinal fluid gamma-aminobutyric acid in patients with panic disorder.
Topics: Adult; Alprazolam; Antidepressive Agents, Tricyclic; Female; GABA Modulators; gamma-Aminobutyric Acid; Humans; Imipramine; Male; Middle Aged; Panic Disorder; Psychiatric Status Rating Scales; Synaptic Transmission | 1995 |
Therapeutic outcome in neuropathic pain: relationship to evidence of nervous system lesion.
Topics: Acetates; Adult; Aged; Amines; Chi-Square Distribution; Cyclohexanecarboxylic Acids; Depression; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Imipramine; Male; Middle Aged; Pain; Pain Measurement; Sensation Disorders; Trauma, Nervous System; Treatment Outcome | 2004 |
Low-dose gabapentin as useful adjuvant to opioids for neuropathic cancer pain when combined with low-dose imipramine.
Topics: Aged; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Imipramine; Male; Middle Aged; Neoplasms; Pain; Pain Measurement; Peripheral Nervous System Diseases | 2010 |
48 other study(ies) available for imipramine and gamma-aminobutyric acid
Article | Year |
---|---|
Orally active and potent inhibitors of gamma-aminobutyric acid uptake.
Topics: 4-Aminobutyrate Transaminase; Administration, Oral; Alkylation; Amino Acids; Animals; Brain; Carboxylic Acids; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Neurotransmitter; Stereoisomerism; Synaptosomes | 1985 |
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship | 2008 |
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship | 2010 |
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
Topics: Animals; Area Under Curve; Humans; Intestinal Absorption; Ligands; Male; Metabolic Clearance Rate; Models, Chemical; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Pyrrolidinones; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship | 2013 |
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.
Topics: Acetamides; Allosteric Regulation; Animals; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism; Structure-Activity Relationship | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Drug Design; Epilepsy; Male; Mice; Microsomes, Liver; Molecular Structure; Pilocarpine | 2016 |
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship | 2017 |
GABA levels in cerebrospinal fluid of patients with Huntington's chorea: a preliminary report.
Topics: Adult; Aged; Aminobutyrates; Amitriptyline; Chlorpromazine; Diazepam; Female; gamma-Aminobutyric Acid; Haloperidol; Humans; Huntington Disease; Imipramine; Male; Middle Aged; Thioridazine; Time Factors | 1975 |
Effects of drugs on gamma-aminobutyric acid receptors, uptake, release and synthesis in vitro.
Topics: Aminobutyrates; Animals; Astacoidea; Bicuculline; Brain; Diazepam; gamma-Aminobutyric Acid; Haloperidol; Imipramine; In Vitro Techniques; Male; Mice; Penicillin G; Pentylenetetrazole; Picrotoxin; Receptors, Drug; Synaptosomes | 1978 |
[Complex treatment of obsessive states of different etiology].
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Benactyzine; Diazepam; Drug Therapy, Combination; Female; gamma-Aminobutyric Acid; Humans; Imipramine; Male; Methapyrilene; Middle Aged; Obsessive-Compulsive Disorder; Perphenazine; Trifluoperazine | 1978 |
Calcium-induced release of gamma-aminobutyric acid from synaptosomes: effects of tranquilizer drugs.
Topics: Aminobutyrates; Animals; Biological Transport; Brain; Calcium; Chlorpromazine; Diazepam; gamma-Aminobutyric Acid; Haloperidol; Imipramine; Male; Mice; Synaptosomes; Tranquilizing Agents | 1977 |
Binding of gamma-aminobutyric acid to crayfish muscle and its relationship to receptor sites.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Astacoidea; Bicuculline; Binding Sites; Chlorpromazine; gamma-Aminobutyric Acid; Imipramine; In Vitro Techniques; Mercaptoethanol; Muscle Proteins; Muscles; Picrotoxin; Protein Binding | 1975 |
[Effect of neuroleptics and antidepressants on the process of gamma-aminobutyric acid-H3 uptake by isolated rat brain nerve endings].
Topics: Aminobutyrates; Animals; Antidepressive Agents; Cerebral Cortex; Chlorpromazine; Fluphenazine; gamma-Aminobutyric Acid; Imipramine; In Vitro Techniques; Male; Phenothiazines; Psychotropic Drugs; Rats; Synaptosomes; Trifluoperazine | 1975 |
Effects of the antidepressant/antipanic drug phenelzine on GABA concentrations and GABA-transaminase activity in rat brain.
Topics: 4-Aminobutyrate Transaminase; Animals; Antidepressive Agents; Brain; Desipramine; Dose-Response Relationship, Drug; Frontal Lobe; gamma-Aminobutyric Acid; Imipramine; Male; Panic; Phenelzine; Rats; Rats, Inbred Strains; Tranylcypromine | 1992 |
GABA, depression and the mechanism of action of antidepressant drugs: a neuroendocrine approach.
Topics: Adult; Amitriptyline; Antidepressive Agents; Baclofen; Brain; Depressive Disorder; Fluoxetine; gamma-Aminobutyric Acid; Growth Hormone; Humans; Imipramine; Male; Middle Aged; Personality Tests; Receptors, GABA-A | 1990 |
Monoamine content in rat brain during carcinogenesis and the influence of the CNS drugs piracetam and imipramine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Brain Neoplasms; Caudate Nucleus; Female; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Hypothalamus; Imipramine; Methylcholanthrene; Norepinephrine; Phenylacetates; Piracetam; Pyrrolidinones; Rats; Rats, Inbred Strains | 1985 |
[Pharmacological studies on Y-8894 (VI). The effect on monoamine uptake and turnover in mouse brain].
Topics: Animals; Biogenic Amines; Brain; Central Nervous System Stimulants; Dihydroergotoxine; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Hydroxyindoleacetic Acid; Imipramine; Male; Methoxyhydroxyphenylglycol; Mice; Morpholines; Norepinephrine; Pantothenic Acid; Serotonin | 1987 |
Antidepressants and seizure-interactions at the GABA-receptor chloride-ionophore complex.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cerebral Cortex; Chlorides; Desipramine; gamma-Aminobutyric Acid; Imipramine; Ion Channels; Ionophores; Male; Mianserin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures | 1988 |
Imipramine and GABA-stimulated chloride uptake in rat cortex.
Topics: Animals; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Imipramine; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
Decreased gamma-aminobutyric acid (GABA) modulatory effect on rat vas deferens neurotransmission after chronic administration of imipramine.
Topics: Animals; Baclofen; Clonidine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Humans; Imipramine; Isoproterenol; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Synaptic Transmission; Vas Deferens | 1989 |
Parallel changes in the sensitivity of gamma-aminobutyric acid and noradrenergic receptors following chronic administration of antidepressant and GABAergic drugs. A possible role in affective disorders.
Topics: Animals; Anticonvulsants; Antidepressive Agents; Baclofen; Cerebral Cortex; Dihydroalprenolol; gamma-Aminobutyric Acid; Hippocampus; Humans; Imipramine; Isoxazoles; Kinetics; Male; Mice; Mood Disorders; Nomifensine; Receptors, Adrenergic; Receptors, GABA-A | 1985 |
GABAergic effects of reserpine following chronic treatment.
Topics: Animals; Baclofen; Binding, Competitive; Cerebral Cortex; Dihydroalprenolol; gamma-Aminobutyric Acid; Hippocampus; Imipramine; Isoxazoles; Male; Mice; Receptors, GABA-A; Reserpine | 1985 |
Effect of chronic imipramine or baclofen on GABA-B binding and cyclic AMP production in cerebral cortex.
Topics: Animals; Baclofen; Cerebral Cortex; Cyclic AMP; gamma-Aminobutyric Acid; Imipramine; Male; Mice; Norepinephrine; Receptors, GABA-A | 1986 |
Fengabine, a novel antidepressant GABAergic agent. I. Activity in models for antidepressant drugs and psychopharmacological profile.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Bicuculline; Chlorophenols; Clomipramine; Depressive Disorder; Disease Models, Animal; gamma-Aminobutyric Acid; Imipramine; Male; Olfactory Bulb; Rats; Receptors, GABA-A; Seizures; Sleep | 1987 |
Fengabine, a novel antidepressant GABAergic agent. II. Effect on cerebral noradrenergic, serotonergic and GABAergic transmission in the rat.
Topics: Animals; Antidepressive Agents; Brain; Chlorophenols; Clonidine; Dihydroalprenolol; gamma-Aminobutyric Acid; Imipramine; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin; Spiperone; Synaptic Transmission | 1987 |
[Pharmacological studies on Y-8894. (III). Its effect on the abnormal electrocorticogram induced by destruction of the internal capsule].
Topics: Amantadine; Animals; Cerebral Cortex; Delta Rhythm; Electroencephalography; gamma-Aminobutyric Acid; Imipramine; Male; Morpholines; Pantothenic Acid; Rats; Rats, Inbred Lew; Theta Rhythm | 1986 |
Noradrenergic rather than GABAergic processes as the common mediation of the antidepressant profile of GABA agonists and imipramine-like drugs in animals.
Topics: Animals; Antidepressive Agents; Brain; Depression; Disease Models, Animal; gamma-Aminobutyric Acid; Imipramine; Male; Muscimol; Norepinephrine; Penbutolol; Picrotoxin; Prazosin; Rats; Rats, Inbred Strains | 1987 |
[Action of neurotropic substances on gamma-aminobutyric acid release from brain synaptosomes during K+ depolarization].
Topics: Animals; Biological Transport, Active; Brain; Calcium; Chlorpromazine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Imipramine; In Vitro Techniques; Male; Phenothiazines; Potassium; Psychotropic Drugs; Rats; Synaptosomes; Trifluperidol | 1985 |
Pharmacological manipulations of the substantia innominata-cortical cholinergic pathway.
Topics: Animals; Basal Ganglia; Cerebral Cortex; Choline; Enkephalins; gamma-Aminobutyric Acid; Glutamates; Imipramine; Male; Muscimol; Neural Inhibition; Neural Pathways; Neurotransmitter Agents; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Substantia Innominata | 1984 |
Additivity of neurochemical changes in learned helplessness and imipramine.
Topics: Animals; Cerebral Cortex; gamma-Aminobutyric Acid; Helplessness, Learned; Hippocampus; Humans; Imipramine; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Serotonin; Septum Pellucidum; Serotonin | 1982 |
Effects of the two antidepressant drugs mianserin and indalpine on the serotonergic system: single-cell studies in the rat.
Topics: Action Potentials; Animals; Antidepressive Agents; Dibenzazepines; gamma-Aminobutyric Acid; Hippocampus; Imipramine; Lysergic Acid Diethylamide; Male; Mianserin; Neurons; Norepinephrine; Piperidines; Pyramidal Tracts; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists | 1984 |
[Atypical antidepressants: effect on synaptosomal uptake of serotonin and GABA].
Topics: Animals; Antidepressive Agents; Brain; Carbazoles; Carbolines; Clomipramine; Depression, Chemical; Desipramine; gamma-Aminobutyric Acid; Imipramine; In Vitro Techniques; Oxazines; Piperazines; Rats; Serotonin; Synaptosomes; Trazodone | 1981 |
GABA-mediated synaptic interaction between the visual and vestibular pathways of Hermissenda.
Topics: Animals; Atropine; Bicuculline; Chlorides; Chromatography, High Pressure Liquid; Electric Conductivity; gamma-Aminobutyric Acid; Hair Cells, Auditory; Imipramine; Immunohistochemistry; Membrane Potentials; Mollusca; Nicotinic Acids; Potassium; Synapses; Visual Pathways | 1993 |
Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography.
Topics: 20-alpha-Dihydroprogesterone; Adrenalectomy; Animals; Brain; Castration; Fluoxetine; GABA Modulators; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Imipramine; Male; Paroxetine; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley | 1996 |
[D-cycloserine is active in the adult mouse and inactive in the aged mouse, in the forced swim test].
Topics: Aging; Animals; Avoidance Learning; Cycloserine; GABA Agonists; gamma-Aminobutyric Acid; Imipramine; Male; Mice; Motor Activity; Muscarinic Agonists; Psychotropic Drugs; Stress, Psychological; Swimming | 1998 |
NMDA receptor involvement in imipramine withdrawal-associated effects on swim stress, GABA levels and NMDA receptor binding in rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hippocampus; Imipramine; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stress, Psychological; Substance Withdrawal Syndrome; Swimming | 2002 |
Experimental conditions for the continuous subcutaneous infusion of four central analgesics in rats.
Topics: Acetates; Amines; Analgesics; Anesthetics, Dissociative; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Chronic Disease; Convulsants; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Hypothermia; Imipramine; Infusion Pumps, Implantable; Ketamine; Male; Morphine; Pain; Pain Measurement; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Solubility; Tetrabenazine | 2002 |
Large-amplitude 5-HT1A receptor activation: a new mechanism of profound, central analgesia.
Topics: Acetates; Adrenergic Uptake Inhibitors; Amines; Aminopyridines; Analgesia; Analgesics; Animals; Cells, Cultured; CHO Cells; Cricetinae; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Synergism; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hyperalgesia; Imipramine; Ketamine; Male; Morphine; Pain; Pain Measurement; Pain Threshold; Piperidines; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Time Factors; Transfection | 2002 |
GABAergic system and imipramine-induced impairment of memory retention in rats.
Topics: Animals; Avoidance Learning; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Imipramine; Male; Memory Disorders; Rats; Rats, Wistar; Receptors, GABA-B; Retention, Psychology | 2004 |
The effect of antinociceptive drugs tested at different times after nerve injury in rats.
Topics: Amines; Analgesics; Animals; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Imipramine; Male; Pain; Pain Measurement; Peripheral Nerve Injuries; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley; Time Factors | 2005 |
Evaluation of ketamine, nimodipine, gabapentin and imipramine in partial sciatic nerve transection model of neuropathic pain in rat: an experimental study.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Imipramine; Ketamine; Male; Nimodipine; Rats; Rats, Wistar; Sciatic Nerve; Sciatic Neuropathy | 2007 |
Direct alteration of a specific inhibitory circuit of the hippocampus by antidepressants.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Biogenic Monoamines; CA1 Region, Hippocampal; Data Interpretation, Statistical; Electroencephalography; Evoked Potentials; Excitatory Postsynaptic Potentials; Female; Fluoxetine; gamma-Aminobutyric Acid; Hippocampus; Imipramine; Inhibition, Psychological; Interneurons; Male; Nerve Net; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Selective Serotonin Reuptake Inhibitors; Synaptic Transmission | 2012 |
Compounded ointment results in severe toxicity in a pediatric patient.
Topics: Administration, Cutaneous; Amines; Analgesics; Body Surface Area; Bradycardia; Clonidine; Combined Modality Therapy; Consciousness Disorders; Cyclohexanecarboxylic Acids; Diaper Rash; Drug Combinations; Drug Compounding; Drug Overdose; Emergencies; Gabapentin; gamma-Aminobutyric Acid; Humans; Imipramine; Infant; Intensive Care Units, Pediatric; Intubation, Intratracheal; Ketamine; Lidocaine; Male; Mefenamic Acid; Ointments; Reflex, Abnormal; Respiration Disorders; Skin Absorption | 2013 |
The effect of GABAmimetics on the duration of immobility in the forced swim test in albino mice.
Topics: Alprazolam; Animals; Depression; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; GABA Modulators; gamma-Aminobutyric Acid; Hypokinesia; Imipramine; Injections, Intraperitoneal; Male; Mice; Motor Activity; Pyridines; Stress, Psychological; Swimming; Time Factors; Vigabatrin; Zolpidem | 2014 |
Loss of Ahi1 impairs neurotransmitter release and causes depressive behaviors in mice.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Behavior, Animal; Depressive Disorder, Major; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Imipramine; Mice; Mice, Knockout; Neurotransmitter Agents; Proto-Oncogene Proteins; Serotonin | 2014 |
Effects of Adjuvant Analgesics on Cerebral Ischemia-Induced Mechanical Allodynia.
Topics: Amines; Analgesics; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Brain Ischemia; Carbamazepine; Chemotherapy, Adjuvant; Cyclohexanecarboxylic Acids; Cyclopropanes; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Imipramine; Indomethacin; Male; Mexiletine; Mice; Milnacipran; Morphine; Neuralgia; Paroxetine; Selective Serotonin Reuptake Inhibitors | 2016 |
The anxiolytic-like effect of 6-styryl-2-pyrone in mice involves GABAergic mechanism of action.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Diazepam; Flumazenil; gamma-Aminobutyric Acid; Hippocampus; Imipramine; Male; Mice; Pyrones; Styrenes | 2018 |