imipramine and gamma-aminobutyric acid

imipramine has been researched along with gamma-aminobutyric acid in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199026 (48.15)18.7374
1990's7 (12.96)18.2507
2000's8 (14.81)29.6817
2010's13 (24.07)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ali, FE; Bondinell, WE; Dandridge, PA; Frazee, JS; Garvey, E; Girard, GR; Kaiser, C; Ku, TW; Lafferty, JJ; Moonsammy, GI1
Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM1
Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG1
Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K1
Anzini, M; Brogi, S; Butini, S; Campiani, G; Cappelli, A; Caselli, G; Castriconi, F; Gemma, S; Giordani, A; Giorgi, G; Giuliani, G; Lanza, M; Letari, O; Makovec, F; Manini, M; Mennuni, L; Valenti, S1
Belyakov, S; Dambrova, M; Kazoka, H; Kuznecovs, J; Lebedev, A; Liepinsh, E; Mishnev, A; Orlova, N; Ponomaryov, Y; Vavers, E; Veinberg, G; Vikainis, S; Vilskersts, R; Vorona, M; Zvejniece, L1
Bellman, K; Knegtel, RM; Settimo, L1
Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E1
Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E1
Glaeser, BS; Hare, TA; Oleweiler, DB; Vogel, WH1
Greenlee, D; Olsen, RW; Ticku, MK; Van Ness, PC1
Kutin, GV; Kutin, VP1
Bayless, JD; Lamar, EE; Olsen, RW1
Ban, M; Lee, JM; Olsen, RW1
Maĭsov, NI; Raevskiĭ, KS1
Baker, GB; Greenshaw, AJ; Martin, IL; McKenna, KF; McManus, DJ1
Iovino, M; Maj, M; Monteleone, P; Steardo, L1
Nitsch, C; von Metzler, A1
Anami, K; Maruyama, Y; Sakamori, M; Setoguchi, M; Takehara, S1
Ikeda, M; Knapp, RJ; Malatynska, E; Yamamura, HI1
Corda, MG; Fernandez Teruel, A; Longoni, B1
Ballejo, G; Calixto, JB; Strobel, GH1
Gianutsos, G; Suzdak, PD3
Bartholini, G; Depoortere, H; Lloyd, KG; Sanger, D; Zivkovic, B1
Arbilla, S; Bartholini, G; Claustre, Y; Dedek, J; Dennis, T; Langer, SZ; Lloyd, KG; Scatton, B; Zivkovic, B1
Anami, K; Fukuda, T; Maruyama, Y; Morimoto, Y; Setoguchi, M; Usa, T1
Danti, S; Martin, P; Poncelet, M; Simon, P; Soubrié, P1
Kryzhanovskiĭ, GN; Maĭsov, NI; Nikushkin, EV1
Wenk, GL1
Berrettini, WH; Gershon, ES; Goldin, LR; Nurnberger, JI1
Petty, F; Sherman, AD1
Bartholini, G; Broekkamp, C; Depoortere, H; Fournier, V; Lloyd, KG; Morselli, PL; Scatton, B; Worms, P; Zivkovic, B1
Blier, P; de Montigny, C; Tardif, D1
Avdulov, NA; Maĭsov, NI1
Alkon, DL; Anderson, MJ; Collin, C; Fass, DM; Kapetanovic, IM; Kuzirian, AJ; Matzel, LD; Nelson, TJ; Rogers, DF1
Halonen, T; Jolkkonen, J; Lepola, U; Riekkinen, P; Rimón, R1
Cooper, TB; Costa, E; Guidotti, A; Uzunov, DP1
Vamvakides, A1
Brand, L; Harvey, BH; Heenop, M; Jonker, LP; Stein, DJ1
Bruins Slot, LA; Colpaert, FC; Koek, W; Ribet, JP; Tarayre, JP1
Assié, MB; Bardin, L; Carilla-Durand, E; Colpaert, FC; Cosi, C; Koek, W; Pauwels, PJ; Tarayre, JP; Vacher, B; Wiesenfeld-Hallin, Z; Xu, XJ1
Azarmina, P; Rostami, P; Shafaghi, B; Shamsi, T; Zarrindast, MR1
Bach, FW; Jensen, TS; Rasmussen, PV; Sindrup, SH1
Borsook, D; Hama, AT1
Bansal, V; Hota, D; Pattanaik, S1
Arai, YC; Arakawa, M; Hayashi, R; Kinoshita, A; Kobayashi, K; Kondo, M; Matsubara, S; Matsubara, T; Nishida, K; Nishihara, M; Shimo, K; Suetomi, K; Suzuki, C; Tohyama, Y; Ushida, T1
Bacci, A; Méndez, P; Pazienti, A; Szabó, G1
Holland, MG; Marraffa, JM; Ryzewski, M; Sullivan, RW1
El Zahaf, NA; Salem Elhwuegi, A1
Li, J; Miao, Z; Qian, X; Ren, L; Sun, M; Xu, X; Zhai, L1
Harada, S; Matsuura, W; Tokuyama, S1
Barbosa-Filho, JM; Chaves, EMC; Dantas, LP; Honório-Júnior, JER; Lúcio, ASSC; Monteiro, VS; Nonato, DTT; Patrocínio, MCA; Sousa, CNS; Vasconcelos, SMM; Viana, GSB1

Reviews

2 review(s) available for imipramine and gamma-aminobutyric acid

ArticleYear
The role of receptor binding in drug discovery.
    Journal of natural products, 1993, Volume: 56, Issue:4

    Topics: Animals; Drug Design; Humans; Receptors, Drug

1993
Genetic factors in affective illness.
    Journal of psychiatric research, 1984, Volume: 18, Issue:4

    Topics: ABO Blood-Group System; Blood Platelets; Cholinergic Fibers; Diseases in Twins; Female; gamma-Aminobutyric Acid; Genetic Linkage; Genetic Markers; HLA Antigens; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Imipramine; Mood Disorders; Pregnancy; Sleep, REM; Twins, Monozygotic; Tyramine; X Chromosome

1984

Trials

4 trial(s) available for imipramine and gamma-aminobutyric acid

ArticleYear
The potential use of GABA agonists in psychiatric disorders: evidence from studies with progabide in animal models and clinical trials.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:6

    Topics: Adjustment Disorders; Animals; Anticonvulsants; Biogenic Amines; Brain; Clinical Trials as Topic; Corpus Striatum; Depressive Disorder; Disease Models, Animal; Dopamine; gamma-Aminobutyric Acid; Humans; Imipramine; Limbic System; Neurons; Rats

1983
Cerebrospinal fluid gamma-aminobutyric acid in patients with panic disorder.
    Biological psychiatry, 1995, Dec-01, Volume: 38, Issue:11

    Topics: Adult; Alprazolam; Antidepressive Agents, Tricyclic; Female; GABA Modulators; gamma-Aminobutyric Acid; Humans; Imipramine; Male; Middle Aged; Panic Disorder; Psychiatric Status Rating Scales; Synaptic Transmission

1995
Therapeutic outcome in neuropathic pain: relationship to evidence of nervous system lesion.
    European journal of neurology, 2004, Volume: 11, Issue:8

    Topics: Acetates; Adult; Aged; Amines; Chi-Square Distribution; Cyclohexanecarboxylic Acids; Depression; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Imipramine; Male; Middle Aged; Pain; Pain Measurement; Sensation Disorders; Trauma, Nervous System; Treatment Outcome

2004
Low-dose gabapentin as useful adjuvant to opioids for neuropathic cancer pain when combined with low-dose imipramine.
    Journal of anesthesia, 2010, Volume: 24, Issue:3

    Topics: Aged; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Imipramine; Male; Middle Aged; Neoplasms; Pain; Pain Measurement; Peripheral Nervous System Diseases

2010

Other Studies

48 other study(ies) available for imipramine and gamma-aminobutyric acid

ArticleYear
Orally active and potent inhibitors of gamma-aminobutyric acid uptake.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:5

    Topics: 4-Aminobutyrate Transaminase; Administration, Oral; Alkylation; Amino Acids; Animals; Brain; Carboxylic Acids; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Neurotransmitter; Stereoisomerism; Synaptosomes

1985
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
    Journal of medicinal chemistry, 2008, Nov-27, Volume: 51, Issue:22

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship

2008
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship

2010
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: Animals; Area Under Curve; Humans; Intestinal Absorption; Ligands; Male; Metabolic Clearance Rate; Models, Chemical; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Pyrrolidinones; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship

2013
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.
    Bioorganic & medicinal chemistry, 2013, May-15, Volume: 21, Issue:10

    Topics: Acetamides; Allosteric Regulation; Animals; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism; Structure-Activity Relationship

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
    Bioorganic & medicinal chemistry, 2016, Apr-15, Volume: 24, Issue:8

    Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Drug Design; Epilepsy; Male; Mice; Microsomes, Liver; Molecular Structure; Pilocarpine

2016
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
    Bioorganic & medicinal chemistry, 2017, 01-15, Volume: 25, Issue:2

    Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship

2017
GABA levels in cerebrospinal fluid of patients with Huntington's chorea: a preliminary report.
    Biochemical medicine, 1975, Volume: 12, Issue:4

    Topics: Adult; Aged; Aminobutyrates; Amitriptyline; Chlorpromazine; Diazepam; Female; gamma-Aminobutyric Acid; Haloperidol; Humans; Huntington Disease; Imipramine; Male; Middle Aged; Thioridazine; Time Factors

1975
Effects of drugs on gamma-aminobutyric acid receptors, uptake, release and synthesis in vitro.
    Brain research, 1978, Jan-13, Volume: 139, Issue:2

    Topics: Aminobutyrates; Animals; Astacoidea; Bicuculline; Brain; Diazepam; gamma-Aminobutyric Acid; Haloperidol; Imipramine; In Vitro Techniques; Male; Mice; Penicillin G; Pentylenetetrazole; Picrotoxin; Receptors, Drug; Synaptosomes

1978
[Complex treatment of obsessive states of different etiology].
    Vrachebnoe delo, 1978, Issue:3

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Benactyzine; Diazepam; Drug Therapy, Combination; Female; gamma-Aminobutyric Acid; Humans; Imipramine; Male; Methapyrilene; Middle Aged; Obsessive-Compulsive Disorder; Perphenazine; Trifluoperazine

1978
Calcium-induced release of gamma-aminobutyric acid from synaptosomes: effects of tranquilizer drugs.
    Journal of neurochemistry, 1977, Volume: 28, Issue:2

    Topics: Aminobutyrates; Animals; Biological Transport; Brain; Calcium; Chlorpromazine; Diazepam; gamma-Aminobutyric Acid; Haloperidol; Imipramine; Male; Mice; Synaptosomes; Tranquilizing Agents

1977
Binding of gamma-aminobutyric acid to crayfish muscle and its relationship to receptor sites.
    Molecular pharmacology, 1975, Volume: 11, Issue:5

    Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Astacoidea; Bicuculline; Binding Sites; Chlorpromazine; gamma-Aminobutyric Acid; Imipramine; In Vitro Techniques; Mercaptoethanol; Muscle Proteins; Muscles; Picrotoxin; Protein Binding

1975
[Effect of neuroleptics and antidepressants on the process of gamma-aminobutyric acid-H3 uptake by isolated rat brain nerve endings].
    Biulleten' eksperimental'noi biologii i meditsiny, 1975, Volume: 79, Issue:6

    Topics: Aminobutyrates; Animals; Antidepressive Agents; Cerebral Cortex; Chlorpromazine; Fluphenazine; gamma-Aminobutyric Acid; Imipramine; In Vitro Techniques; Male; Phenothiazines; Psychotropic Drugs; Rats; Synaptosomes; Trifluoperazine

1975
Effects of the antidepressant/antipanic drug phenelzine on GABA concentrations and GABA-transaminase activity in rat brain.
    Biochemical pharmacology, 1992, Jun-09, Volume: 43, Issue:11

    Topics: 4-Aminobutyrate Transaminase; Animals; Antidepressive Agents; Brain; Desipramine; Dose-Response Relationship, Drug; Frontal Lobe; gamma-Aminobutyric Acid; Imipramine; Male; Panic; Phenelzine; Rats; Rats, Inbred Strains; Tranylcypromine

1992
GABA, depression and the mechanism of action of antidepressant drugs: a neuroendocrine approach.
    Journal of affective disorders, 1990, Volume: 20, Issue:1

    Topics: Adult; Amitriptyline; Antidepressive Agents; Baclofen; Brain; Depressive Disorder; Fluoxetine; gamma-Aminobutyric Acid; Growth Hormone; Humans; Imipramine; Male; Middle Aged; Personality Tests; Receptors, GABA-A

1990
Monoamine content in rat brain during carcinogenesis and the influence of the CNS drugs piracetam and imipramine.
    Die Naturwissenschaften, 1985, Volume: 72, Issue:10

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Brain Neoplasms; Caudate Nucleus; Female; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Hypothalamus; Imipramine; Methylcholanthrene; Norepinephrine; Phenylacetates; Piracetam; Pyrrolidinones; Rats; Rats, Inbred Strains

1985
[Pharmacological studies on Y-8894 (VI). The effect on monoamine uptake and turnover in mouse brain].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1987, Volume: 90, Issue:1

    Topics: Animals; Biogenic Amines; Brain; Central Nervous System Stimulants; Dihydroergotoxine; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Hydroxyindoleacetic Acid; Imipramine; Male; Methoxyhydroxyphenylglycol; Mice; Morpholines; Norepinephrine; Pantothenic Acid; Serotonin

1987
Antidepressants and seizure-interactions at the GABA-receptor chloride-ionophore complex.
    Life sciences, 1988, Volume: 43, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents; Cerebral Cortex; Chlorides; Desipramine; gamma-Aminobutyric Acid; Imipramine; Ion Channels; Ionophores; Male; Mianserin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures

1988
Imipramine and GABA-stimulated chloride uptake in rat cortex.
    Biological psychiatry, 1989, Apr-01, Volume: 25, Issue:7

    Topics: Animals; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Imipramine; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A

1989
Decreased gamma-aminobutyric acid (GABA) modulatory effect on rat vas deferens neurotransmission after chronic administration of imipramine.
    Cellular and molecular neurobiology, 1989, Volume: 9, Issue:4

    Topics: Animals; Baclofen; Clonidine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Humans; Imipramine; Isoproterenol; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Synaptic Transmission; Vas Deferens

1989
Parallel changes in the sensitivity of gamma-aminobutyric acid and noradrenergic receptors following chronic administration of antidepressant and GABAergic drugs. A possible role in affective disorders.
    Neuropharmacology, 1985, Volume: 24, Issue:3

    Topics: Animals; Anticonvulsants; Antidepressive Agents; Baclofen; Cerebral Cortex; Dihydroalprenolol; gamma-Aminobutyric Acid; Hippocampus; Humans; Imipramine; Isoxazoles; Kinetics; Male; Mice; Mood Disorders; Nomifensine; Receptors, Adrenergic; Receptors, GABA-A

1985
GABAergic effects of reserpine following chronic treatment.
    Psychopharmacology, 1985, Volume: 87, Issue:2

    Topics: Animals; Baclofen; Binding, Competitive; Cerebral Cortex; Dihydroalprenolol; gamma-Aminobutyric Acid; Hippocampus; Imipramine; Isoxazoles; Male; Mice; Receptors, GABA-A; Reserpine

1985
Effect of chronic imipramine or baclofen on GABA-B binding and cyclic AMP production in cerebral cortex.
    European journal of pharmacology, 1986, Nov-12, Volume: 131, Issue:1

    Topics: Animals; Baclofen; Cerebral Cortex; Cyclic AMP; gamma-Aminobutyric Acid; Imipramine; Male; Mice; Norepinephrine; Receptors, GABA-A

1986
Fengabine, a novel antidepressant GABAergic agent. I. Activity in models for antidepressant drugs and psychopharmacological profile.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1

    Topics: Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Bicuculline; Chlorophenols; Clomipramine; Depressive Disorder; Disease Models, Animal; gamma-Aminobutyric Acid; Imipramine; Male; Olfactory Bulb; Rats; Receptors, GABA-A; Seizures; Sleep

1987
Fengabine, a novel antidepressant GABAergic agent. II. Effect on cerebral noradrenergic, serotonergic and GABAergic transmission in the rat.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1

    Topics: Animals; Antidepressive Agents; Brain; Chlorophenols; Clonidine; Dihydroalprenolol; gamma-Aminobutyric Acid; Imipramine; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin; Spiperone; Synaptic Transmission

1987
[Pharmacological studies on Y-8894. (III). Its effect on the abnormal electrocorticogram induced by destruction of the internal capsule].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 88, Issue:4

    Topics: Amantadine; Animals; Cerebral Cortex; Delta Rhythm; Electroencephalography; gamma-Aminobutyric Acid; Imipramine; Male; Morpholines; Pantothenic Acid; Rats; Rats, Inbred Lew; Theta Rhythm

1986
Noradrenergic rather than GABAergic processes as the common mediation of the antidepressant profile of GABA agonists and imipramine-like drugs in animals.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 28, Issue:3

    Topics: Animals; Antidepressive Agents; Brain; Depression; Disease Models, Animal; gamma-Aminobutyric Acid; Imipramine; Male; Muscimol; Norepinephrine; Penbutolol; Picrotoxin; Prazosin; Rats; Rats, Inbred Strains

1987
[Action of neurotropic substances on gamma-aminobutyric acid release from brain synaptosomes during K+ depolarization].
    Biulleten' eksperimental'noi biologii i meditsiny, 1985, Volume: 99, Issue:4

    Topics: Animals; Biological Transport, Active; Brain; Calcium; Chlorpromazine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Imipramine; In Vitro Techniques; Male; Phenothiazines; Potassium; Psychotropic Drugs; Rats; Synaptosomes; Trifluperidol

1985
Pharmacological manipulations of the substantia innominata-cortical cholinergic pathway.
    Neuroscience letters, 1984, Sep-28, Volume: 51, Issue:1

    Topics: Animals; Basal Ganglia; Cerebral Cortex; Choline; Enkephalins; gamma-Aminobutyric Acid; Glutamates; Imipramine; Male; Muscimol; Neural Inhibition; Neural Pathways; Neurotransmitter Agents; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Substantia Innominata

1984
Additivity of neurochemical changes in learned helplessness and imipramine.
    Behavioral and neural biology, 1982, Volume: 35, Issue:4

    Topics: Animals; Cerebral Cortex; gamma-Aminobutyric Acid; Helplessness, Learned; Hippocampus; Humans; Imipramine; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Serotonin; Septum Pellucidum; Serotonin

1982
Effects of the two antidepressant drugs mianserin and indalpine on the serotonergic system: single-cell studies in the rat.
    Psychopharmacology, 1984, Volume: 84, Issue:2

    Topics: Action Potentials; Animals; Antidepressive Agents; Dibenzazepines; gamma-Aminobutyric Acid; Hippocampus; Imipramine; Lysergic Acid Diethylamide; Male; Mianserin; Neurons; Norepinephrine; Piperidines; Pyramidal Tracts; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists

1984
[Atypical antidepressants: effect on synaptosomal uptake of serotonin and GABA].
    Biulleten' eksperimental'noi biologii i meditsiny, 1981, Volume: 92, Issue:11

    Topics: Animals; Antidepressive Agents; Brain; Carbazoles; Carbolines; Clomipramine; Depression, Chemical; Desipramine; gamma-Aminobutyric Acid; Imipramine; In Vitro Techniques; Oxazines; Piperazines; Rats; Serotonin; Synaptosomes; Trazodone

1981
GABA-mediated synaptic interaction between the visual and vestibular pathways of Hermissenda.
    Journal of neurochemistry, 1993, Volume: 61, Issue:2

    Topics: Animals; Atropine; Bicuculline; Chlorides; Chromatography, High Pressure Liquid; Electric Conductivity; gamma-Aminobutyric Acid; Hair Cells, Auditory; Imipramine; Immunohistochemistry; Membrane Potentials; Mollusca; Nicotinic Acids; Potassium; Synapses; Visual Pathways

1993
Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Oct-29, Volume: 93, Issue:22

    Topics: 20-alpha-Dihydroprogesterone; Adrenalectomy; Animals; Brain; Castration; Fluoxetine; GABA Modulators; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Imipramine; Male; Paroxetine; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley

1996
[D-cycloserine is active in the adult mouse and inactive in the aged mouse, in the forced swim test].
    Annales pharmaceutiques francaises, 1998, Volume: 56, Issue:5

    Topics: Aging; Animals; Avoidance Learning; Cycloserine; GABA Agonists; gamma-Aminobutyric Acid; Imipramine; Male; Mice; Motor Activity; Muscarinic Agonists; Psychotropic Drugs; Stress, Psychological; Swimming

1998
NMDA receptor involvement in imipramine withdrawal-associated effects on swim stress, GABA levels and NMDA receptor binding in rat hippocampus.
    Life sciences, 2002, May-24, Volume: 71, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hippocampus; Imipramine; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stress, Psychological; Substance Withdrawal Syndrome; Swimming

2002
Experimental conditions for the continuous subcutaneous infusion of four central analgesics in rats.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 72, Issue:4

    Topics: Acetates; Amines; Analgesics; Anesthetics, Dissociative; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Chronic Disease; Convulsants; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Hypothermia; Imipramine; Infusion Pumps, Implantable; Ketamine; Male; Morphine; Pain; Pain Measurement; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Solubility; Tetrabenazine

2002
Large-amplitude 5-HT1A receptor activation: a new mechanism of profound, central analgesia.
    Neuropharmacology, 2002, Volume: 43, Issue:6

    Topics: Acetates; Adrenergic Uptake Inhibitors; Amines; Aminopyridines; Analgesia; Analgesics; Animals; Cells, Cultured; CHO Cells; Cricetinae; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Synergism; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hyperalgesia; Imipramine; Ketamine; Male; Morphine; Pain; Pain Measurement; Pain Threshold; Piperidines; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Time Factors; Transfection

2002
GABAergic system and imipramine-induced impairment of memory retention in rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2004, Volume: 14, Issue:1

    Topics: Animals; Avoidance Learning; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Imipramine; Male; Memory Disorders; Rats; Rats, Wistar; Receptors, GABA-B; Retention, Psychology

2004
The effect of antinociceptive drugs tested at different times after nerve injury in rats.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:1

    Topics: Amines; Analgesics; Animals; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Imipramine; Male; Pain; Pain Measurement; Peripheral Nerve Injuries; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley; Time Factors

2005
Evaluation of ketamine, nimodipine, gabapentin and imipramine in partial sciatic nerve transection model of neuropathic pain in rat: an experimental study.
    Methods and findings in experimental and clinical pharmacology, 2007, Volume: 29, Issue:7

    Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Imipramine; Ketamine; Male; Nimodipine; Rats; Rats, Wistar; Sciatic Nerve; Sciatic Neuropathy

2007
Direct alteration of a specific inhibitory circuit of the hippocampus by antidepressants.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Nov-21, Volume: 32, Issue:47

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Biogenic Monoamines; CA1 Region, Hippocampal; Data Interpretation, Statistical; Electroencephalography; Evoked Potentials; Excitatory Postsynaptic Potentials; Female; Fluoxetine; gamma-Aminobutyric Acid; Hippocampus; Imipramine; Inhibition, Psychological; Interneurons; Male; Nerve Net; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Selective Serotonin Reuptake Inhibitors; Synaptic Transmission

2012
Compounded ointment results in severe toxicity in a pediatric patient.
    Pediatric emergency care, 2013, Volume: 29, Issue:11

    Topics: Administration, Cutaneous; Amines; Analgesics; Body Surface Area; Bradycardia; Clonidine; Combined Modality Therapy; Consciousness Disorders; Cyclohexanecarboxylic Acids; Diaper Rash; Drug Combinations; Drug Compounding; Drug Overdose; Emergencies; Gabapentin; gamma-Aminobutyric Acid; Humans; Imipramine; Infant; Intensive Care Units, Pediatric; Intubation, Intratracheal; Ketamine; Lidocaine; Male; Mefenamic Acid; Ointments; Reflex, Abnormal; Respiration Disorders; Skin Absorption

2013
The effect of GABAmimetics on the duration of immobility in the forced swim test in albino mice.
    The Libyan journal of medicine, 2014, Volume: 9, Issue:1

    Topics: Alprazolam; Animals; Depression; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; GABA Modulators; gamma-Aminobutyric Acid; Hypokinesia; Imipramine; Injections, Intraperitoneal; Male; Mice; Motor Activity; Pyridines; Stress, Psychological; Swimming; Time Factors; Vigabatrin; Zolpidem

2014
Loss of Ahi1 impairs neurotransmitter release and causes depressive behaviors in mice.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Adaptor Proteins, Vesicular Transport; Animals; Behavior, Animal; Depressive Disorder, Major; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Imipramine; Mice; Mice, Knockout; Neurotransmitter Agents; Proto-Oncogene Proteins; Serotonin

2014
Effects of Adjuvant Analgesics on Cerebral Ischemia-Induced Mechanical Allodynia.
    Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:5

    Topics: Amines; Analgesics; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Brain Ischemia; Carbamazepine; Chemotherapy, Adjuvant; Cyclohexanecarboxylic Acids; Cyclopropanes; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Imipramine; Indomethacin; Male; Mexiletine; Mice; Milnacipran; Morphine; Neuralgia; Paroxetine; Selective Serotonin Reuptake Inhibitors

2016
The anxiolytic-like effect of 6-styryl-2-pyrone in mice involves GABAergic mechanism of action.
    Metabolic brain disease, 2018, Volume: 33, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Diazepam; Flumazenil; gamma-Aminobutyric Acid; Hippocampus; Imipramine; Male; Mice; Pyrones; Styrenes

2018