imipramine and fluvoxamine

imipramine has been researched along with fluvoxamine in 100 studies

Research

Studies (100)

TimeframeStudies, this research(%)All Research%
pre-199016 (16.00)18.7374
1990's34 (34.00)18.2507
2000's33 (33.00)29.6817
2010's16 (16.00)24.3611
2020's1 (1.00)2.80

Authors

AuthorsStudies
Koe, BK; Kraska, AR; Sarges, R; Welch, WM1
Topliss, JG; Yoshida, F1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Qin, W; Tian, S; Wold, EA; Xu, Q; Ye, N; Zhen, XC; Zhou, J1
Brøsen, K; Skjelbo, E1
Avenoso, A; Campo, GM; Caputi, AP; Pollicino, MA; Spina, E1
Kapur, S; Mann, JJ1
Kellett, JM1
Broekkamp, CL; Jenck, F; Van Delft, AM1
Bradshaw, CM; Shah, K; Szabadi, E1
Greist, JH; Jefferson, JW; Kobak, KA; March, JS; Mazza, J1
Baignoli, G; Ecari, U; Gonella, G1
Azorin, JM; Bovier, P; Jeanningros, R; Tissot, R; Widmer, J1
Ballenger, JC; Kellner, C; Laird, LK; Laraia, MT; Lydiard, RB; Morton, WA; Steele, TE1
Boyer, WF; Feighner, JP; Hendrickson, GG; Meredith, CH1
Asberg, M; Eriksson, B; Mårtensson, B; Träskman-Bendz, L; Wägner, A1
Cassano, GB; Conti, L; Levine, J; Massimetti, G; Mengali, F; Waekelin, JS1
Badoe, K; Browne, M; Horn, E; Lapierre, YD; Oyewumi, LK; Roberts, N; Sarantidis, D; Tessier, P1
Wakelin, JS1
Dreyfus, JF; Guelfi, JD; Pichot, P2
Bovier, P; Gaillard, JM; Tissot, R; Widmer, J1
Dominguez, RA; Goldstein, BJ; Jacobson, AF; Steinbook, RM1
Bhat, AV; Norton, KR; Paykel, ES; Rao, B; Sireling, LI1
Coleman, BS; Itil, TM; Michael, ST; Mukherjee, S; Shrivastava, RK1
Ban, TA; Fjetland, OK; Guy, W; King, DL; Manov, G; Wilson, WH1
Bradford, D; Krijzer, F; Snelder, M1
Constantinidis, J; Dick, P; Tissot, R1
Baba, T; Lee, JW; Shibuya, T; Takada, K; Takeda, H1
Banki, CM1
Ashford, JJ1
Kasper, S; Möller, HJ; Montgomery, SA; Zondag, E1
Brady, KT; Joffe, R; Kellner, CH; Laird, LK; Lydiard, RB; Morton, WA; Steele, TE1
Jordan, S; Kramer, GL; Moeller, M; Petty, F; Zukas, PK1
Avenoso, A; Campo, GM; Caputi, AP; Pollicino, AM; Spina, E1
Ballenger, JC; Kellner, C; Laird, LK; Lydiard, RB; Morton, WA; Steele, TE; Thompson, NM1
Avenoso, A; Campo, GM; Caputi, AP; Perucca, E; Pollicino, AM; Spina, E1
Lam, RW; Maskall, DD1
Brøsen, K; Loft, S; Poulsen, HE; Rasmussen, BB; Skjelbo, E1
Brieaddy, L; Cooper, B; Ferris, RM; Hollingsworth, E; Mehta, N; Rigdon, G; Soroko, F; Wang, C; Wastila, W1
Claghorn, JL; Earl, CQ; Houser, VP; Kanter, D; Stoner, KA; Walczak, DD; Wong, LF1
Birkhimer, LJ; Fabre, L; Kapik, BM; Wong, LF; Zaborny, BA1
Artigas, F; Bel, N1
Brøsen, K1
Artigas, F; Bel, N; Casanovas, JM; Romero, L1
Bakish, D; Charbonneau, Y; Filteau, MJ; Fraser, G; Hooper, CL; Raine, D; Thibaudeau, C; West, DL1
Amin, M; Bakish, D; Nair, NP; Saxena, B; Schwartz, G; West, TE1
Bourin, M; Redrobe, JP1
Ahern, D; Ball, SE; Kao, J; Scatina, J1
Fundaró, A1
Huang, SL; Xu, ZH; Zhou, HH1
Meyers, BS1
Ekstrom, RD; Golden, RN; Lydiard, RB; Mason, GA; Miller, HL1
Iga, T; Odagiri, Y; Ohtani, H; Sato, H; Sawada, Y1
Arisaka, O; Kano, K1
Okuyama, S; Takamori, K; Yoshida, S2
Broekman, TG; de Kemp, EC; Goedhart, A; Hoogduin, CA; Moleman, P; Schaap, CP; van den Berg, PC1
Kwasucki, J; Maksymiuk, G; Olbrych-Karpińska, B; Stepień, A1
Hashimoto, S; Hattori, T; Kawasaki, K; Kitamura, Y; Miki, N; Mochizuki, D; Otsuka, Y; Tsujita, R; Yamada, S1
Bruijn, JA; Passchier, J; Pepplinkhuizen, L; Tulen, JH; Van Den Broek, WW; Volkers, AC1
Gibert-Rahola, J; Gutiérrez, M; Micó, JA; Ortega-Alvaro, A1
Bruyn, JA; Passchier, J; Pepplinkhuizen, L; Tulen, JH; van den Broek, WW; Volkers, AC1
Birkenhäger, TK; Bruijn, JA; Moleman, P; Mulder, PG; van den Broek, WW3
Avissar, S; Matuzany-Ruban, A; Schreiber, G; Tzukert, K1
Birkenhäger, TK; Bruijn, JA; Moleman, P; van den Broek, WW; Vulto, AG1
Hayashi, T; Kumamaru, E; Kunugi, H; Numakawa, T; Su, TP; Yagasaki, Y1
Higuchi, H; Sugawara, Y; Yoshida, K1
Ishida, H; Iwata, M; Kawahara, R; Shirayama, Y1
Bruijn, JA; Tulen, JH; van den Broek, WW; Volkers, AC1
Brocco, M; Dekeyne, A; Millan, MJ; Papp, M1
Aoki, M; Chiba, H; Harada, Y; Matsumiya, T; Nohara, J; Takeda, H; Tsuji, M1
Daws, LC; Frosto-Burke, T; Hensler, JG; Munn, JL; Valdez, MF1
Hazui, T; Hori, S; Matsuo, N; Miki, A; Nakano, M; Ohtani, H; Sawada, Y; Suzuki, Y; Yagi, H; Yamamoto, A1
Birkenhäger, TK; Bruijn, JA; Fekkes, D; Moleman, P; Mulder, PG; van den Broek, WW1
Hallifax, D; Houston, JB1
Ikenouchi-Sugita, A; Nakamura, J; Yoshimura, R1
Birkenhäger, TK; Heijnen, WT; Mulder, PG; van den Broek, WW1
Ara, A; Banu, N; Zafir, A1
Birkenhäger, TK; Mulder, PG; van den Broek, WW; Vermeiden, M1
Bantsiele, GB; Bentué-Ferrer, D; Bourin, M; Laviolle, B; Reymann, JM; Saïkali, S1
Aburakawa, Y; Aizawa, H; Hasebe, N; Kwak, S; Sawada, J; Yamashita, T1
Balci, F; Campbell, U; Hanania, T; Olivier, BE; Paterson, NE1
Birkenhäger, TK; Van Den Broek, WW1
Hara, H; Hayashi, E; Kinoshita, M; Kuratani, K1
Hara, H; Hayashi, E; Kinoshita, M; Kuratani, K; Shimamura, M1
Preskorn, SH1
Kasahara, J; Oka, N; Tezuka, K; Uchida, H1
Matsumoto, M; Niwa, T; Shizuku, M; Yanai, M1

Reviews

10 review(s) available for imipramine and fluvoxamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Small Molecules Selectively Targeting Sigma-1 Receptor for the Treatment of Neurological Diseases.
    Journal of medicinal chemistry, 2020, 12-24, Volume: 63, Issue:24

    Topics: Allosteric Regulation; Clinical Trials as Topic; Humans; Ligands; Nervous System Diseases; Piperidines; Receptors, sigma; Sigma-1 Receptor; Small Molecule Libraries

2020
The emergence of suicidal ideation and behavior during antidepressant pharmacotherapy.
    Archives of general psychiatry, 1991, Volume: 48, Issue:11

    Topics: Antidepressive Agents; Depressive Disorder; Desipramine; Drug Therapy, Combination; Fluoxetine; Fluvoxamine; Humans; Imipramine; Mianserin; Suicide

1991
Fluvoxamine: an antidepressant for the elderly?
    Journal of psychiatry & neuroscience : JPN, 1991, Volume: 16, Issue:2 Suppl 1

    Topics: Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder; Dothiepin; Fluvoxamine; Humans; Imipramine; Mianserin; Middle Aged; Serotonin Antagonists

1991
Therapeutic effects of serotonin uptake inhibitors in depression.
    The Journal of clinical psychiatry, 1986, Volume: 47 Suppl

    Topics: 5-Hydroxytryptophan; Alanine; Citalopram; Depressive Disorder; Fluoxetine; Fluvoxamine; Humans; Imipramine; Oximes; Paroxetine; Piperidines; Propylamines; Serotonin; Serotonin Antagonists; Trazodone; Zimeldine

1986
Fluvoxamine and tricyclic antidepressants (TCAs): how do the TCAs compare as "new" drugs with established fluvoxamine?
    International clinical psychopharmacology, 1995, Volume: 9 Suppl 4

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Binding Sites; Cost-Benefit Analysis; Depressive Disorder; Fluvoxamine; Humans; Imipramine; Selective Serotonin Reuptake Inhibitors

1995
Drug interactions and the cytochrome P450 system. The role of cytochrome P450 1A2.
    Clinical pharmacokinetics, 1995, Volume: 29 Suppl 1

    Topics: Animals; Antidepressive Agents, Second-Generation; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Fluvoxamine; Humans; Imipramine; Oxidoreductases; Selective Serotonin Reuptake Inhibitors

1995
Depression and dementia: comorbidities, identification, and treatment.
    Journal of geriatric psychiatry and neurology, 1998,Winter, Volume: 11, Issue:4

    Topics: Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Benzamides; Citalopram; Clomipramine; Cognition Disorders; Comorbidity; Dementia; Depression; Female; Fluoxetine; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Neuropsychological Tests; Nortriptyline; Selective Serotonin Reuptake Inhibitors; Sertraline

1998
[Review of pharmacological efficacies and side effects of antidepressants].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Volume: 65, Issue:9

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Fluvoxamine; Humans; Imipramine; Maprotiline; Paroxetine; Sulpiride; Trazodone

2007
Clinical psychopharmacology and medical malpractice: the four Ds.
    Journal of psychiatric practice, 2014, Volume: 20, Issue:5

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Child; Depressive Disorder; Desipramine; Fatal Outcome; Female; Fluvoxamine; Forensic Psychiatry; Humans; Imipramine; Male; Malpractice; Mental Disorders; Psychopharmacology; Schizophrenia; Thioridazine

2014

Trials

31 trial(s) available for imipramine and fluvoxamine

ArticleYear
A double-blind, placebo-controlled trial of fluvoxamine versus imipramine in outpatients with major depression.
    The Journal of clinical psychiatry, 1990, Volume: 51, Issue:5

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Fluvoxamine; Humans; Imipramine; Middle Aged; Oximes; Placebos

1990
Fluvoxamine and imipramine in the treatment of depressive patients: a double-blind controlled study.
    Current medical research and opinion, 1990, Volume: 12, Issue:3

    Topics: Adult; Aged; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Drug Administration Schedule; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Oximes

1990
Fluvoxamine, imipramine, and placebo in the treatment of depressed outpatients: effects on depression.
    Psychopharmacology bulletin, 1989, Volume: 25, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Outpatients; Oximes; Random Allocation

1989
A placebo-controlled inpatient comparison of fluvoxamine maleate and imipramine in major depression.
    International clinical psychopharmacology, 1989, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Oximes; Placebos; Psychiatric Status Rating Scales; Random Allocation

1989
Use of a standardized documentation system (BLIPS/BDP) in the conduct of a multicenter international trial comparing fluvoxamine, imipramine, and placebo.
    Psychopharmacology bulletin, 1986, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Depressive Disorder; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Multi-Institutional Systems; Oximes; Research Design

1986
Treatment of major affective disorder with fluvoxamine.
    The Journal of clinical psychiatry, 1987, Volume: 48, Issue:2

    Topics: Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Oximes; Personality Inventory; Placebos; Psychiatric Status Rating Scales; Random Allocation

1987
Fluvoxamine in the treatment of the older depressed patient; double-blind, placebo-controlled data.
    International clinical psychopharmacology, 1986, Volume: 1, Issue:3

    Topics: Aged; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Oximes; Time Factors

1986
Fluvoxamine and imipramine: results of a long-term controlled trial.
    International clinical psychopharmacology, 1987, Volume: 2, Issue:2

    Topics: Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; Humans; Imipramine; Long-Term Care; Male; Middle Aged; Oximes; Psychiatric Status Rating Scales

1987
A double-blind placebo-controlled study of fluvoxamine and imipramine in depression.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:3

    Topics: Adult; Aged; Ambulatory Care; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Nausea; Oximes; Patient Dropouts; Placebos; Psychiatric Status Rating Scales; Sleep Initiation and Maintenance Disorders; Vomiting; Xerostomia

1985
A double-blind comparison of fluvoxamine, imipramine and placebo in depressed patients.
    Journal of affective disorders, 1984, Volume: 7, Issue:3-4

    Topics: Adult; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; Humans; Imipramine; Male; Oximes; Psychological Tests

1984
A double-blind controlled clinical trial comparing fluvoxamine with imipramine.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 3

    Topics: Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Electroencephalography; Female; Fluvoxamine; Hemodynamics; Humans; Imipramine; Male; Oximes; Psychiatric Status Rating Scales

1983
A double-blind placebo-controlled study of fluvoxamine and imipramine in out-patients with primary depression.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 3

    Topics: Adult; Aged; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Electroencephalography; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Oximes; Psychiatric Status Rating Scales

1983
A double-blind clinical trial of fluvoxamine and imipramine in patients with primary depression.
    Psychopharmacology bulletin, 1984,Winter, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Oximes; Random Allocation

1984
Antidepressant efficacy in relation to item analysis and severity of depression: a placebo-controlled trial of fluvoxamine versus imipramine.
    International clinical psychopharmacology, 1995, Volume: 9 Suppl 4

    Topics: Adult; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Retrospective Studies; Severity of Illness Index; Treatment Outcome

1995
A comparison of the effects of imipramine and fluvoxamine on the thyroid axis.
    Biological psychiatry, 1994, Dec-01, Volume: 36, Issue:11

    Topics: Adult; Analysis of Variance; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Thyroid Gland; Thyroid Hormones

1994
Cardiovascular effects of imipramine, fluvoxamine, and placebo in depressed outpatients.
    The Journal of clinical psychiatry, 1993, Volume: 54, Issue:6

    Topics: Adult; Aged; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Depressive Disorder; Electrocardiography; Female; Fluvoxamine; Heart Rate; Humans; Hypotension, Orthostatic; Imipramine; Male; Middle Aged; Placebos; Pulse

1993
Fluvoxamine maleate in the treatment of depression: a single-center, double-blind, placebo-controlled comparison with imipramine in outpatients.
    Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:2

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Personality Inventory; Treatment Outcome

1996
Fluvoxamine versus imipramine and placebo: a double-blind comparison in depressed patients.
    International clinical psychopharmacology, 1996, Volume: 11, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Constipation; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Nausea; Selective Serotonin Reuptake Inhibitors

1996
A double-blind placebo-controlled trial comparing fluvoxamine and imipramine in the treatment of panic disorder with or without agoraphobia.
    Psychopharmacology bulletin, 1996, Volume: 32, Issue:1

    Topics: Adult; Agoraphobia; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fluvoxamine; Humans; Imipramine; Male; Panic Disorder; Psychiatric Status Rating Scales; Time Factors

1996
Comparison of fluvoxamine, imipramine, and placebo in the treatment of outpatients with panic disorder.
    Anxiety, 1996, Volume: 2, Issue:4

    Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Double-Blind Method; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Panic Disorder; Personality Inventory; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

1996
Noradrenergic function and clinical outcome in antidepressant pharmacotherapy.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 24, Issue:6

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Depression; Fluvoxamine; Humans; Imipramine; Melatonin; Norepinephrine; Pineal Gland; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2001
Diagnosis at the first episode to differentiate antidepressant treatment responses in patients with mood and anxiety disorders.
    Psychopharmacology, 2002, Volume: 160, Issue:1

    Topics: Adult; Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Anxiety Disorders; Diagnosis, Differential; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Mood Disorders; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2002
[Evaluation of analgesic action of fluvoxamine compared with efficacy of imipramine and tramadol for treatment of sciatica--open trial].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2002, Volume: 55, Issue:1-2

    Topics: Adult; Aged; Analgesics, Opioid; Antidepressive Agents; Female; Fluvoxamine; Follow-Up Studies; Humans; Imipramine; Male; Middle Aged; Sciatica; Tramadol; Treatment Outcome

2002
Effects of imipramine, fluvoxamine and depressive mood on autonomic cardiac functioning in major depressive disorder.
    Pharmacopsychiatry, 2004, Volume: 37, Issue:1

    Topics: Adult; Affect; Aged; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Autonomic Nervous System; Blood Pressure; Depressive Disorder, Major; Double-Blind Method; Electrocardiography; Female; Fluvoxamine; Heart; Heart Rate; Humans; Imipramine; Male; Middle Aged; Personality Inventory; Treatment Outcome

2004
A double-blind randomized study comparing imipramine with fluvoxamine in depressed inpatients.
    Psychopharmacology, 2004, Volume: 175, Issue:4

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Double-Blind Method; Female; Fluvoxamine; Humans; Imipramine; Inpatients; Male; Middle Aged; Patient Compliance; Patient Dropouts; Psychiatric Status Rating Scales; Treatment Outcome

2004
Comparison of two-phase treatment with imipramine or fluvoxamine, both followed by lithium addition, in inpatients with major depressive disorder.
    The American journal of psychiatry, 2004, Volume: 161, Issue:11

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluvoxamine; Hospitalization; Humans; Imipramine; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Treatment Outcome

2004
Imipramine dose in relation to therapeutic plasma level: are clinical trials using imipramine as a positive control flawed?
    Psychopharmacology, 2005, Volume: 181, Issue:3

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fluvoxamine; Humans; Imipramine; Male; Metabolic Clearance Rate; Mianserin; Middle Aged; Mirtazapine; Treatment Outcome

2005
[Comparison of the effectiveness of two treatment strategies in inpatients with a depressive disorder. A double-blind study of imipramine followed by lithium addition versus fluvoxamine followed by lithium addition].
    Tijdschrift voor psychiatrie, 2006, Volume: 48, Issue:4

    Topics: Adult; Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Method; Drug Synergism; Female; Fluvoxamine; Humans; Imipramine; Lithium; Male; Middle Aged; Treatment Outcome

2006
Sustained effects of phenelzine and tranylcypromine on orthostatic challenge in antidepressant-refractory depression.
    Journal of clinical psychopharmacology, 2006, Volume: 26, Issue:5

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Blood Pressure; Depressive Disorder, Major; Double-Blind Method; Drug Resistance; Female; Fluvoxamine; Humans; Hypotension, Orthostatic; Imipramine; Male; Middle Aged; Monoamine Oxidase Inhibitors; Phenelzine; Psychiatric Status Rating Scales; Tranylcypromine; Treatment Outcome

2006
Prevalence of trait anxiety in a sample of depressed inpatients and its influence on response to antidepressants.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:4

    Topics: Adult; Aged; Antidepressive Agents; Anxiety; Depressive Disorder; Diazepam; Double-Blind Method; Female; Fluvoxamine; Humans; Imipramine; Inpatients; Male; Middle Aged; Netherlands; Predictive Value of Tests; Prevalence; Psychiatric Status Rating Scales; Severity of Illness Index; Time Factors; Treatment Outcome

2010
Influence of gender and menopausal status on antidepressant treatment response in depressed inpatients.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:4

    Topics: Adult; Aged; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Female; Fluvoxamine; Humans; Imipramine; Inpatients; Linear Models; Male; Menopause; Middle Aged; Netherlands; Psychiatric Status Rating Scales; Sex Factors; Single-Blind Method; Surveys and Questionnaires; Treatment Outcome; Young Adult

2010

Other Studies

59 other study(ies) available for imipramine and fluvoxamine

ArticleYear
Nontricyclic antidepressant agents derived from cis- and trans-1-amino-4-aryltetralins.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:11

    Topics: Animals; Antidepressive Agents; Dopamine; Isomerism; Male; Naphthalenes; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Synaptosomes; Tetrahydronaphthalenes; X-Ray Diffraction

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations

2002
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
    Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Inhibitors of imipramine metabolism by human liver microsomes.
    British journal of clinical pharmacology, 1992, Volume: 34, Issue:3

    Topics: Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Fluvoxamine; Humans; Hydroxylation; Imipramine; In Vitro Techniques; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; Polymorphism, Genetic; Quinidine; Selective Serotonin Reuptake Inhibitors

1992
Interaction between fluvoxamine and imipramine/desipramine in four patients.
    Therapeutic drug monitoring, 1992, Volume: 14, Issue:3

    Topics: Depressive Disorder; Desipramine; Drug Interactions; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged

1992
The effect of antidepressants on aversive periaqueductal gray stimulation in rats.
    European journal of pharmacology, 1990, Feb-27, Volume: 177, Issue:3

    Topics: 1-Naphthylamine; Animals; Antidepressive Agents; Biogenic Monoamines; Dopamine; Dose-Response Relationship, Drug; Electric Stimulation; Fluvoxamine; Imipramine; Male; Nomifensine; Norepinephrine; Oximes; Periaqueductal Gray; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Serotonin; Sertraline

1990
Interaction between antidepressants and d-amphetamine on variable-interval performance.
    Psychopharmacology, 1990, Volume: 100, Issue:4

    Topics: Animals; Antidepressive Agents; Desipramine; Dextroamphetamine; Dose-Response Relationship, Drug; Female; Fluvoxamine; Imipramine; Oximes; Psychomotor Performance; Rats; Rats, Inbred Strains; Reinforcement Schedule; Serotonin Antagonists; Trazodone

1990
L-tyrosine and L-tryptophan membrane transport in erythrocytes and antidepressant drug choice.
    Biological psychiatry, 1990, Apr-01, Volume: 27, Issue:7

    Topics: Adult; Aged; Antidepressive Agents; Depressive Disorder; Erythrocyte Membrane; Female; Fluvoxamine; Humans; Imipramine; Male; Mianserin; Middle Aged; Monoamine Oxidase Inhibitors; Oximes; Piperidines; Receptors, Adrenergic; Receptors, Serotonin; Tryptophan; Tyrosine

1990
Evolution of red blood cell membrane transport and plasma level of L-tyrosine and L-tryptophan in depressed treated patients according to clinical improvement.
    Neuropsychobiology, 1988, Volume: 19, Issue:3

    Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Desipramine; Erythrocyte Membrane; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Oximes; Psychological Tests; Tryptophan; Tyrosine

1988
Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model.
    Neuropsychobiology, 1984, Volume: 12, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Fluvoxamine; Imipramine; Male; Maprotiline; Mianserin; Oximes; Rats; Rats, Inbred Strains; Seizures; Viloxazine

1984
Antidepressants and serotonin neurons of the raphe.
    Neuropsychobiology, 1981, Volume: 7, Issue:3

    Topics: Animals; Antidepressive Agents, Tricyclic; Benzofurans; Brain Stem; Citalopram; Clomipramine; Ethers; Fluvoxamine; Imipramine; Indoles; Locus Coeruleus; Male; Microscopy, Fluorescence; Norepinephrine; Oximes; Piperidines; Propylamines; Raphe Nuclei; Rats; Receptors, Serotonin; Serotonin

1981
[Effect of fluvoxamine, a new antidepressant drug, on monoamine dynamics in the rat cerebral limbic system and its pharmacological characteristic].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1995, Volume: 105, Issue:3

    Topics: Administration, Oral; Amygdala; Animals; Biogenic Monoamines; Fluvoxamine; Hippocampus; Hydroxyindoleacetic Acid; Imipramine; Limbic System; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin

1995
Prophylactic potential of selective reuptake inhibitors in suicidal patients.
    International clinical psychopharmacology, 1995, Volume: 9 Suppl 4

    Topics: Binding Sites; Depressive Disorder; Fluvoxamine; Frontal Lobe; Humans; Hydroxyindoleacetic Acid; Imipramine; Selective Serotonin Reuptake Inhibitors; Suicide; Suicide, Attempted

1995
In vivo biogenic amine efflux in medial prefrontal cortex with imipramine, fluoxetine, and fluvoxamine.
    Synapse (New York, N.Y.), 1994, Volume: 18, Issue:4

    Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Fluoxetine; Fluvoxamine; Imipramine; Male; Microdialysis; Norepinephrine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Serotonin

1994
Fluvoxamine-induced alterations in plasma concentrations of imipramine and desipramine in depressed patients.
    International journal of clinical pharmacology research, 1993, Volume: 13, Issue:3

    Topics: Adult; Depressive Disorder; Desipramine; Drug Interactions; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged

1993
Effect of fluvoxamine on the pharmacokinetics of imipramine and desipramine in healthy subjects.
    Therapeutic drug monitoring, 1993, Volume: 15, Issue:3

    Topics: Adult; Desipramine; Drug Interactions; Fluvoxamine; Humans; Imipramine; Male

1993
Increased plasma concentration of imipramine following augmentation with fluvoxamine.
    The American journal of psychiatry, 1993, Volume: 150, Issue:10

    Topics: Adult; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Female; Fluvoxamine; Humans; Imipramine; Male; Parasympathetic Nervous System; Stimulation, Chemical

1993
Fluvoxamine is a potent inhibitor of cytochrome P4501A2.
    Biochemical pharmacology, 1993, Mar-24, Volume: 45, Issue:6

    Topics: Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Fluvoxamine; Humans; Imipramine; Kinetics; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenacetin; Theophylline

1993
Pharmacological properties of 403U76, a new chemical class of 5-hydroxytryptamine- and noradrenaline-reuptake inhibitor.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:9

    Topics: 5-Hydroxytryptophan; Adrenergic Uptake Inhibitors; Animals; Animals, Newborn; Benzyl Alcohols; Binding, Competitive; Dogs; Electrophysiology; Fluoxetine; Fluvoxamine; Hemodynamics; Imipramine; Male; Mice; Neurons; Norepinephrine; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Species Specificity; Synaptic Transmission; Tetrabenazine; Vocalization, Animal

1995
In vivo effects of the simultaneous blockade of serotonin and norepinephrine transporters on serotonergic function. Microdialysis studies.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Animals; Carrier Proteins; Cerebral Cortex; Citalopram; Clonidine; Desipramine; Fluoxetine; Fluvoxamine; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Raphe Nuclei; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters

1996
Adaptative changes of the serotonergic system after antidepressant treatments.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Clomipramine; Clorgyline; Fluvoxamine; Frontal Lobe; Hydroxyindoleacetic Acid; Imipramine; Microdialysis; Monoamine Oxidase Inhibitors; Piperidines; Pyrimidines; Raphe Nuclei; Rats; Serotonin; Stereotaxic Techniques; Tranylcypromine; Tryptophan

1996
Partial role of 5-HT2 and 5-HT3 receptors in the activity of antidepressants in the mouse forced swimming test.
    European journal of pharmacology, 1997, May-01, Volume: 325, Issue:2-3

    Topics: Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Desipramine; Drug Interactions; Fluoxetine; Fluvoxamine; Imipramine; Ketanserin; Male; Maprotiline; Mice; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming

1997
Venlafaxine: in vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs, and effects on human hepatic CYP3A4, CYP2C9 and CYP1A2.
    British journal of clinical pharmacology, 1997, Volume: 43, Issue:6

    Topics: 1-Naphthylamine; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cyclohexanols; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desipramine; Fluoxetine; Fluvoxamine; Frozen Sections; Humans; Hydroxylation; Imipramine; In Vitro Techniques; Lethal Dose 50; Microsomes, Liver; Mixed Function Oxygenases; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Venlafaxine Hydrochloride

1997
Pinch-induced catalepsy in mice: a useful model to investigate antidepressant or anxiolytic drugs.
    Progress in neuro-psychopharmacology & biological psychiatry, 1998, Volume: 22, Issue:1

    Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Antidepressive Agents; Catalepsy; Female; Fluoxetine; Fluvoxamine; Imipramine; Learning; Male; Mice; Models, Psychological; Motor Activity; Ondansetron; Physical Stimulation; Reaction Time; Serotonin Antagonists; Sex Characteristics; Stereotyped Behavior

1998
Inhibition of imipramine N-demethylation by fluvoxamine in Chinese young men.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1996, Volume: 17, Issue:5

    Topics: Adult; Antidepressive Agents, Tricyclic; Area Under Curve; Desipramine; Drug Interactions; Fluvoxamine; Humans; Imipramine; Male; Selective Serotonin Reuptake Inhibitors

1996
Milnacipran: new preparation. Tricyclics remain first-line antidepressants.
    Prescrire international, 1998, Volume: 7, Issue:34

    Topics: Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Clomipramine; Cyclopropanes; Drug Evaluation; Europe; Fluoxetine; Fluvoxamine; Humans; Imipramine; Meta-Analysis as Topic; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; United States

1998
A comparative pharmacodynamic study of the arrhythmogenicity of antidepressants, fluvoxamine and imipramine, in guinea pigs.
    Biological & pharmaceutical bulletin, 2001, Volume: 24, Issue:5

    Topics: Animals; Antidepressive Agents; Arrhythmias, Cardiac; Electrocardiography; Fluvoxamine; Guinea Pigs; Imipramine; Male

2001
More on fluvoxamine and enuresis.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2001, Volume: 40, Issue:8

    Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Case-Control Studies; Child; Cross-Over Studies; Deamino Arginine Vasopressin; Enuresis; Female; Fluvoxamine; Humans; Imipramine; Male; Renal Agents; Treatment Outcome

2001
Availability of learned helplessness test as a model of depression compared to a forced swimming test in rats.
    Pharmacology, 2001, Volume: 63, Issue:3

    Topics: Amoxapine; Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Fluvoxamine; Helplessness, Learned; Imipramine; Male; Mianserin; Motor Activity; Rats; Rats, Wistar; Swimming

2001
Repeated treatment with imipramine, fluvoxamine and tranylcypromine decreases the number of escape failures by activating dopaminergic systems in a rat learned helplessness test.
    Life sciences, 2001, Sep-07, Volume: 69, Issue:16

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antidepressive Agents; Benzazepines; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Escape Reaction; Fluvoxamine; Helplessness, Learned; Imipramine; Male; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine; Sulpiride; Tetrahydronaphthalenes; Tranylcypromine

2001
Neurochemical and behavioural characterization of milnacipran, a serotonin and noradrenaline reuptake inhibitor in rats.
    Psychopharmacology, 2002, Volume: 162, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Behavior, Animal; Binding, Competitive; Brain Chemistry; Conditioning, Psychological; Cyclopropanes; Dose-Response Relationship, Drug; Fear; Fluoxetine; Fluvoxamine; Imipramine; Male; Maprotiline; Microdialysis; Milnacipran; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Prefrontal Cortex; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Cell Surface; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Swimming; Synaptosomes; Time Factors

2002
24-Hour motor activity after treatment with imipramine or fluvoxamine in major depressive disorder.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2002, Volume: 12, Issue:4

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Female; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Motor Activity; Time Factors

2002
Interactions of acute morphine with chronic imipramine and fluvoxamine treatment on the antinociceptive effect in arthritic rats.
    Neuroscience letters, 2003, Nov-27, Volume: 352, Issue:1

    Topics: Analgesics; Animals; Arthritis, Experimental; Drug Interactions; Fluvoxamine; Imipramine; Male; Morphine; Pain Measurement; Rats; Rats, Wistar

2003
Beta-arrestin-1 levels: reduced in leukocytes of patients with depression and elevated by antidepressants in rat brain.
    The American journal of psychiatry, 2004, Volume: 161, Issue:11

    Topics: Adult; Aged; Animals; Antidepressive Agents; Arrestins; beta-Arrestin 1; beta-Arrestins; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Depressive Disorder; Desipramine; Down-Regulation; Female; Fluvoxamine; Hippocampus; Humans; Imipramine; Leukocytes, Mononuclear; Male; Middle Aged; Psychiatric Status Rating Scales; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Severity of Illness Index

2004
Chronic antidepressants potentiate via sigma-1 receptors the brain-derived neurotrophic factor-induced signaling for glutamate release.
    The Journal of biological chemistry, 2006, May-05, Volume: 281, Issue:18

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Brain-Derived Neurotrophic Factor; Calcium Channels; Fluvoxamine; Glutamic Acid; Imipramine; Inositol 1,4,5-Trisphosphate Receptors; Neurons; Neurotransmitter Agents; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, sigma; Sigma-1 Receptor; Signal Transduction

2006
Dramatic remission of treatment-resistant depression after the cessation of tricyclic antidepressants.
    Pharmacopsychiatry, 2006, Volume: 39, Issue:3

    Topics: Adult; Antidepressive Agents, Tricyclic; Cabergoline; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Ergolines; Female; Fluvoxamine; Humans; Imipramine; Substance Withdrawal Syndrome; Treatment Outcome

2006
Hippocampal synapsin I, growth-associated protein-43, and microtubule-associated protein-2 immunoreactivity in learned helplessness rats and antidepressant-treated rats.
    Neuroscience, 2006, Sep-01, Volume: 141, Issue:3

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Fluvoxamine; GAP-43 Protein; Helplessness, Learned; Hippocampus; Imipramine; Immunohistochemistry; Male; Microtubule-Associated Proteins; Rats; Rats, Sprague-Dawley; Reaction Time; Synapsins; Time Factors

2006
Antidepressant-like properties of the anti-Parkinson agent, piribedil, in rodents: mediation by dopamine D2 receptors.
    Behavioural pharmacology, 2006, Volume: 17, Issue:7

    Topics: Aggression; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antiparkinson Agents; Behavior, Animal; Chronic Disease; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Fluvoxamine; Imipramine; Male; Mice; Motor Activity; Piribedil; Quinpirole; Raclopride; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Social Isolation; Stress, Psychological; Sucrose; Swimming

2006
Antidepressants enhance the antinociceptive effects of carbamazepine in the acetic acid-induced writhing test in mice.
    European journal of pharmacology, 2006, Nov-21, Volume: 550, Issue:1-3

    Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Carbamazepine; Cyclopropanes; Fluvoxamine; Imipramine; Male; Mice; Mice, Inbred ICR; Milnacipran; Pain; Pain Measurement

2006
Serotonin transporter function, but not expression, is dependent on brain-derived neurotrophic factor (BDNF): in vivo studies in BDNF-deficient mice.
    Journal of neurochemistry, 2007, Volume: 101, Issue:3

    Topics: Age Factors; Animals; Autoradiography; Brain-Derived Neurotrophic Factor; Dose-Response Relationship, Drug; Electrochemistry; Female; Fluvoxamine; Gene Expression; Hippocampus; Imipramine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein Binding; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sex Factors

2007
Piloerection induced by replacing fluvoxamine with milnacipran.
    British journal of clinical pharmacology, 2007, Volume: 63, Issue:6

    Topics: Adult; Antidepressive Agents; Cyclopropanes; Female; Fluvoxamine; Humans; Imipramine; Milnacipran; Models, Biological; Norepinephrine; Panic Disorder; Piloerection

2007
Lithium addition in antidepressant-resistant depression: effects on platelet 5-HT, plasma 5-HT and plasma 5-HIAA concentration.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Jun-30, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antimanic Agents; Blood Platelets; Depressive Disorder; Drug Resistance; Female; Fluvoxamine; Humans; Hydroxyindoleacetic Acid; Imipramine; Lithium Compounds; Male; Middle Aged; Psychiatric Status Rating Scales; Serotonin

2007
Saturable uptake of lipophilic amine drugs into isolated hepatocytes: mechanisms and consequences for quantitative clearance prediction.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:8

    Topics: Algorithms; Amines; Animals; Biological Transport; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Dextromethorphan; Fluoxetine; Fluvoxamine; Hepatocytes; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Imipramine; In Vitro Techniques; Kinetics; Male; Models, Biological; Propranolol; Quinine; Rats; Rats, Sprague-Dawley

2007
Invivo antioxidant status: a putative target of antidepressant action.
    Progress in neuro-psychopharmacology & biological psychiatry, 2009, Mar-17, Volume: 33, Issue:2

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antioxidants; Body Weight; Cyclohexanols; Depressive Disorder; Fluvoxamine; Food Preferences; Imipramine; Lipid Peroxidation; Protein Carbonylation; Rats; Restraint, Physical; Stress, Psychological; Swimming; Taste; Venlafaxine Hydrochloride

2009
Behavioral effects of four antidepressants on an ischemic rat model of emotional disturbances.
    Behavioural brain research, 2009, Aug-12, Volume: 201, Issue:2

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Anxiety Disorders; Behavior, Animal; Brain Ischemia; Cyclopropanes; Depressive Disorder; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Fluvoxamine; Hippocampus; Imipramine; Immobility Response, Tonic; Male; Milnacipran; Motor Activity; Rats; Rats, Wistar

2009
Effects of antidepressants on GluR2 Q/R site-RNA editing in modified HeLa cell line.
    Neuroscience research, 2009, Volume: 64, Issue:3

    Topics: Adenosine Deaminase; Amitriptyline; Amyotrophic Lateral Sclerosis; Antidepressive Agents; Arginine; Cyclopropanes; Desipramine; Fluoxetine; Fluvoxamine; Glutamine; HeLa Cells; Humans; Imipramine; Milnacipran; Morpholines; Paroxetine; Reboxetine; Receptors, AMPA; RNA Editing; RNA-Binding Proteins; RNA, Messenger

2009
The triple reuptake inhibitor DOV216,303 exhibits limited antidepressant-like properties in the differential reinforcement of low-rate 72-second responding assay, likely due to dopamine reuptake inhibition.
    Journal of psychopharmacology (Oxford, England), 2011, Volume: 25, Issue:10

    Topics: Animals; Antidepressive Agents; Aza Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bupropion; Desipramine; Diazepam; Dopamine Uptake Inhibitors; Fluvoxamine; Haloperidol; Imipramine; Male; Piperazines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology

2011
Lithium addition to a tricyclic antidepressant results in optimal efficacy.
    Acta psychiatrica Scandinavica, 2011, Volume: 123, Issue:1

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Drug Resistance; Drug Synergism; Fluvoxamine; Humans; Imipramine; Lithium Compounds; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2011
Pharmacologically distinctive behaviors other than burying marbles during the marble burying test in mice.
    Pharmacology, 2010, Volume: 86, Issue:5-6

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Bupropion; Diazepam; Exploratory Behavior; Fluvoxamine; Imipramine; Male; Mice; Motor Activity

2010
Automated experimental system capturing three behavioral components during murine forced swim test.
    Life sciences, 2011, Feb-28, Volume: 88, Issue:9-10

    Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Behavior, Animal; Bupropion; Desipramine; Equipment Design; Fluvoxamine; Image Interpretation, Computer-Assisted; Imipramine; Male; Mice; Mice, Inbred Strains; Pattern Recognition, Automated; Psychomotor Performance; Swimming; Video Recording

2011
Postischemic Anhedonia Associated with Neurodegenerative Changes in the Hippocampal Dentate Gyrus of Rats.
    Neural plasticity, 2016, Volume: 2016

    Topics: Anhedonia; Animals; Antidepressive Agents; Brain Ischemia; Cell Proliferation; Dentate Gyrus; Disease Models, Animal; Fluvoxamine; Imipramine; Male; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley

2016
Effect of Cytochrome P450 (CYP) 2D6 Genetic Polymorphism on the Inhibitory Action of Antidepressants on CYP2D6-Mediated Dopamine Formation from p-Tyramine.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2018, Volume: 21, Issue:1

    Topics: Antidepressive Agents; Brain; Cytochrome P-450 CYP2D6; Desipramine; Dopamine; Dose-Response Relationship, Drug; Fluvoxamine; Humans; Imipramine; Polymorphism, Genetic; Structure-Activity Relationship; Tyramine

2018