imipramine has been researched along with fluoxetine in 379 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (12.14) | 18.7374 |
| 1990's | 113 (29.82) | 18.2507 |
| 2000's | 107 (28.23) | 29.6817 |
| 2010's | 101 (26.65) | 24.3611 |
| 2020's | 12 (3.17) | 2.80 |
| Authors | Studies |
|---|---|
| Costanzo, MJ; Maryanoff, BE; McComsey, DF; Nortey, SO; Shank, RP; Vaught, JL | 1 |
| Costanzo, MJ; Gardocki, JF; Maryanoff, BE; McComsey, DF; Nortey, SO; Schneider, CR; Setler, PE; Shank, RP | 1 |
| Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA | 1 |
| Keserü, GM | 1 |
| Both, FL; Elisabetsky, E; Henriques, AT; Kerber, VA; Meneghini, L | 1 |
| Caron, G; Ermondi, G | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Goetz, RM; Karpowich, NK; Law, CJ; Reith, ME; Wang, DN; Zhen, J; Zhou, Z | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Buck, LB; Petrascheck, M; Ye, X | 1 |
| Jia, L; Sun, H | 1 |
| Bleich, S; Kornhuber, J; Rupprecht, R; Terfloth, L; Wiltfang, J | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Bhosale, SH; Shelke, SM | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ | 1 |
| Sen, S; Sinha, N | 1 |
| Chatterjee, M; Kumar, A; Palit, G; Rao, KB; Sashidhara, KV; Singh, S; Verma, AK | 1 |
| Ali, S; Dutta, A; Gopishetty, B; Hazeldine, S; Johnson, M; Modi, G; Reith, M; Santra, S; Zhen, J | 1 |
| Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Bürger, C; Costa, P; de Oliveira, KN; de Souza, MM; Mazzambani, L; Mora, C; Nunes, RJ; Santin, JR | 1 |
| Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Buckley, DB; Funk, RS; Hensley, T; Kazmi, F; Loewen, GJ; Parkinson, A; Pope, C | 1 |
| Peters, JU | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Choi, K; Moon, B; Park, JE; Roh, EJ; Sim, T; Song, C | 1 |
| Alix, K; Dukat, M; Khatri, S; Schulte, MK; Worsham, J | 1 |
| Aruna Teja, G; Bhaskara Rao, K; Gupta, S; Modukuri, RK; Sashidhara, KV; Shukla, S; Singh, S | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Gupta, G; Gupta, S; Lal, J; Maikhuri, JP; Mandalapu, D; Pandey, D; Sharma, V; Sharma, VL; Shukla, M; Shukla, S; Siddiqi, MI; Singh, N; Singh, S; Tanpula, DK; Yadav, SK | 1 |
| Qin, W; Tian, S; Wold, EA; Xu, Q; Ye, N; Zhen, XC; Zhou, J | 1 |
| Bennett, JL; Fetterer, R; Pax, R | 1 |
| Górka, Z; Kwiatek, H; Maj, J; Wojtasik, E | 1 |
| Anestis, DK; Gruetter, CA; Lemke, SM; Szarek, JL; Valentovic, MA | 1 |
| Block, P; Fieve, RR; Peselow, ED; Robins, CJ; Sanfilipo, MP | 1 |
| Difiglia, C; Fieve, RR; Peselow, ED; Sanfilipo, MP | 1 |
| Maj, J; Rogóz, Z; Skuza, G; Sowińska, H | 1 |
| Bertschy, G; Bizouard, P; Bonin, B; François, TH; Nezelof, S; Sechter, D; Vandel, B; Vandel, S | 1 |
| Klein, DF; Quitkin, FM; Stewart, JW | 1 |
| Bergstrom, RF; Lemberger, L; Peyton, AL | 1 |
| Kapur, S; Mann, JJ | 1 |
| Griffin, JH; Hahn, SM | 1 |
| Bolino, F; Casacchia, M; Cupillari, M; Stratta, P | 1 |
| Gale, K; Meloni, R | 1 |
| Brøsen, K; Skjelbo, E | 1 |
| Dewan, M; Masand, P | 1 |
| Griffiths, HW; Marshall, EF; Tyrer, SP | 1 |
| Kafka, MP | 1 |
| Stokes, PE | 1 |
| Nelson, JC; Rosenstein, DL; Takeshita, J | 1 |
| Beasley, CM; Bosomworth, JC; Sayler, ME; Wernicke, JF | 1 |
| Koe, BK; Lebel, LA; Welch, WM | 1 |
| Westwick, F | 1 |
| Breese, GR; Duncan, GE; Hong, JS; Kuhn, C; Mueller, RA; Paul, IA | 1 |
| Iovino, M; Maj, M; Monteleone, P; Steardo, L | 1 |
| Asberg, M; Mårtensson, B; Montero, D; Siwers, B; Wgner, A | 1 |
| Hintz, S; Kuck, J; Peterkin, JJ; Volk, DM; Zisook, S | 1 |
| Esnaud, H; Graham, D; Habert, E; Langer, SZ | 1 |
| Ashbrook, E; Cohn, JB; Collins, G; Wernicke, JF | 1 |
| Deo, R; Levine, S; Mahadevan, K | 2 |
| Boyer, WF; Feighner, JP; Hendrickson, GG; Merideth, CH | 1 |
| Eckert, ED; Hatsukami, D; Mitchell, JE; Pomeroy, C; Pyle, RL; Zimmerman, R | 1 |
| Byerley, WF; Reimherr, FW; Ward, MF | 1 |
| Bressa, GM; Brugnoli, R; Pancheri, P | 1 |
| Albano, C; Gandolfo, C; Loeb, C | 1 |
| Decaria, C; Fairbanks, J; Hollander, E; Liebowitz, MR | 1 |
| Brady, K; Lydiard, RB; Zarzar, M | 1 |
| Eison, AS; Eison, MS; Gianutsos, G; Yocca, FD | 1 |
| Lazo, JS; Myers, CL; Pitt, BR | 1 |
| Asberg, M; Eriksson, B; Mårtensson, B; Träskman-Bendz, L; Wägner, A | 1 |
| Bergström, M; Eriksson, K; Marcusson, JO; Ross, SB | 1 |
| Aronson, CE; Brunswick, DJ; Frazer, A; Kovachich, GB | 1 |
| Broadhurst, AM; Wood, MD; Wyllie, MG | 1 |
| Brown, WA; Dornseif, BE; Wernicke, JF | 1 |
| Hrdina, PD | 1 |
| Byerley, WF; Grosser, BI; Reimherr, FW; Wood, DR | 1 |
| Lapierre, Y; Mehta, G; Surphlis, W; Telner, J | 1 |
| Poshivalov, VP; Valdman, AV | 1 |
| Ieni, JR; Meyerson, LR; Wennogle, LP | 1 |
| Andrews, P; Harder, A; Thomas, H | 1 |
| Cohen, BS; Dillon, D; Fyer, AJ; Gorman, JM; Klein, DF; Liebowitz, MR | 1 |
| Levine, S | 1 |
| Hicks, PE; Langer, SZ; Raisman, R; Schoemaker, H; Segonzac, A; Tateishi, T | 1 |
| Fisch, C | 1 |
| Lalonde, R; Vikis-Freibergs, V | 1 |
| Chuang, DM; Costa, E; Nakaki, T; Roth, BL | 1 |
| Hauser, K; Häusler, A; Meeker, JB | 1 |
| Cohn, JB; Wilcox, C | 1 |
| Hardison, CD; Stark, P | 1 |
| Fennessy, MR; Taylor, DA; Verberne, AJ | 1 |
| Enna, SJ | 1 |
| Barbaccia, ML; Chuang, DM; Costa, E; Gandolfi, O | 1 |
| Brainard, J; Byerley, B; Grosser, BI; Reimherr, FW; Wood, DR | 1 |
| Bremner, JD | 1 |
| Broekkamp, CL; Garrigou, D; Lloyd, KG | 2 |
| Meierl, G; Schmidt, WJ | 1 |
| Shopsin, B | 1 |
| Mogilnicka, E | 1 |
| Agnes, RS; Blanchard, DC; Blanchard, RJ; Griebel, G | 1 |
| Anton, SF; Revicki, DA | 1 |
| Campbell, M; Cueva, JE | 1 |
| Bastide, P; Coudert, P; Rubat, C; Tronche, P | 1 |
| Preskorn, SH | 1 |
| Pétursson, H | 1 |
| Helmeste, DM; Reist, C; Tang, SW; Vu, R | 1 |
| Iny, L; Luthe, L; Pecknold, JC; Ramdoyal, D | 1 |
| Hirschfeld, RM | 1 |
| Hietala, J; Kuoppamäki, M; Laakso, A; Pälvimäki, EP; Syvälahti, E | 1 |
| Greist, JH; Heiligenstein, JH; Jefferson, JW; Koback, K; Sayler, ME; Tollefson, GD; Tollefson, SL | 1 |
| Jordan, S; Kramer, GL; Moeller, M; Petty, F; Zukas, PK | 1 |
| Simon, G; Vonkorff, M; Wagner, E | 1 |
| Alpert, JE; Fava, M; Maddocks, A; Rosenbaum, JF | 1 |
| Asai, K; Mori, H; Nankai, M; Toru, M; Watanabe, A; Yamada, S; Yoshimoto, S | 1 |
| Hammerness, PG; Kaspi, SP; Otto, MW; Pollack, MH; Rosenbaum, JF | 1 |
| Coplan, JD; Gorman, JM; Papp, LA; Tiffon, L | 1 |
| Buysse, DJ; Dettling, J; Frank, E; Kupfer, DJ; Monk, TH; Ritenour, AM | 1 |
| Bhagwat, SV; Bhamre, S; Ravindranath, V; Shankar, SK; Williams, DE | 1 |
| el-Yazigi, A; Raines, DA | 1 |
| Beasley, CM; Holman, SL; Potvin, JH | 1 |
| Balon, R; Pohl, R; Ramesh, C; Yeragani, VK | 1 |
| Nishikawa, T; Shirayama, Y; Takahashi, K; Umino, A | 1 |
| Aulakh, CS; Hill, JL; Lesch, KP; Murphy, DL; Tolliver, TJ; Wolozin, BL | 1 |
| Sheikha, SH; Wagner, KD; Wagner, RF | 1 |
| Short, DD; Workman, EA | 1 |
| Kupfer, DJ | 1 |
| Arup, P; Behnke, K; Christiansen, PE; Geisler, A; Ipsen, E; Maach-Møller, B; Nielsen, BM; Ohrberg, SC | 1 |
| Dewar, KM; Grondin, L; Nénonéné, EK; Ohayon, M; Reader, TA | 1 |
| Ichikawa, J; Meltzer, HY | 1 |
| Gambarana, C; Ghiglieri, O; Graziella de Montis, M | 1 |
| Brieaddy, L; Cooper, B; Ferris, RM; Hollingsworth, E; Mehta, N; Rigdon, G; Soroko, F; Wang, C; Wastila, W | 1 |
| Duman, RS; Nestler, EJ; Nibuya, M | 1 |
| Kaplita, SB; Marcus, RN; Roberts, DL; Robinson, DS; Seminara, JA; Smith, JM; Stringfellow, JC | 1 |
| Grothaus, L; Heiligenstein, JH; Katon, W; Revicki, DA; Simon, GE; VonKorff, M; Wagner, EH | 1 |
| Birkett, MA; Heiligenstein, JH; Knight, DL; Nemeroff, CB; Tollefson, GD; Tollefson, SL | 1 |
| Baker, RA; Brady, LS; Herkenham, M | 1 |
| Leroi, I; Walentynowicz, MA | 1 |
| Dziedzicka-Wasylewska, M; Maj, J; Rogoz, R; Rogóz, Z; Skuza, G | 1 |
| Artigas, F; Bel, N | 1 |
| Hashimoto, K; Minabe, Y; Narita, N; Tomitaka, S | 1 |
| Altemus, M; Galliven, E; Glowa, JR; Leong, YM; Murphy, DL | 1 |
| Matsuki, N; Okada, F; Saito, H | 1 |
| Bushell, I; Newton, W | 1 |
| Hietala, J; Kuoppamäki, M; Laakso, A; Majasuo, H; Pälvimäki, EP; Roth, BL; Syvälahti, E | 1 |
| Cooper, TB; Costa, E; Guidotti, A; Uzunov, DP | 1 |
| De Meester, I; Desnyder, R; Maes, M; Meltzer, HY; Ranjan, R; Scharpe, S | 1 |
| Barros, HM; Belej, T; Manji, D; Nobrega, JN; Sioutis, S | 1 |
| Esposito, A; Gold, PW; Khatri, P; Licinio, J; Wong, ML | 1 |
| Daniel, WA; Wójcikowski, J | 3 |
| Brown, RE; Culpepper, L; Gonzales, J; Hales, RE; Keller, MB; Revicki, DA | 1 |
| Kulkarni, SK; Kumar, S | 1 |
| Agosti, V; Stewart, JW | 1 |
| Bourin, M; Redrobe, JP | 1 |
| Hatsuda, S; Matsubara, M; Miura, K; Murakami, H; Nakazawa, K; Ohara, M; Sugita, S; Suzuki, S; Terashima, M | 1 |
| Ahern, D; Ball, SE; Kao, J; Scatina, J | 1 |
| Boyer, W | 1 |
| Aymard, G; Diquet, B; Livi, P; Pham, YT | 1 |
| Koed, K; Linnet, K | 1 |
| Benjamin, LS | 1 |
| Grothaus, L; Heiligenstein, JH; Katon, W; Revicki, D; Simon, GE | 1 |
| Fundaró, A | 1 |
| Breese, GR; Carson, SW; Duncan, GE; Knapp, DJ | 1 |
| Leander, JD; Wolff, MC | 1 |
| Dewey, MJ; Holladay, JW; Yoo, SD | 1 |
| Béïque, JC; de Montigny, C; Debonnel, G; Lavoie, N | 1 |
| Ichikawa, J; Kuroki, T; Meltzer, HY | 1 |
| Chang, HC; Cheng, JT; Hsieh, CH; Hsieh, JT; Law, HS | 1 |
| Chen, JX; Gershon, MD; Pan, H; Rothman, TP; Wade, PR | 1 |
| Kovárů, H; Lisá, V; Lukásová, E; Rittich, B; Spanová, A | 1 |
| Jagadeesh, SR; Subhash, MN | 1 |
| Anton, SF; Bakish, D; Brown, RE; Feeny, D; Palmer, W; Revicki, DA; Rosser, WW | 1 |
| DeAntonio, M; Freeman, R; Pataki, C; Rao, U; Rigali, J; Schmidt-Lackner, S; Strober, M | 1 |
| Blakely, RD; Jansen, K; Richelson, E; Tatsumi, M | 1 |
| Meyers, BS | 1 |
| Agosti, V | 1 |
| Kristensen, AS; Mortensen, OV; Rudnick, G; Wiborg, O | 1 |
| Bombardelli, E; De Montis, MG; Gambarana, C; Ghiglieri, O; Giachetti, D; Tagliamonte, A; Tolu, P | 1 |
| Joffe, RT; Kamil, R; Levitt, AJ; McIntyre, R | 1 |
| de Beun, R; De Vry, J; Jentzsch, KR; Maurel, S; Schreiber, R | 1 |
| Bolanos, S; Bytautiene, E; Fulep, E; Garfield, RE; Saade, GR; Vedernikov, Y | 1 |
| Janal, MN; Klein, DF; McGrath, PJ; Petkova, E; Quitkin, FM; Stewart, JW | 1 |
| Carlson, EC; de Felipe, C; Harrison, T; Hunt, S; Oates, B; Owen, S; Rupniak, NM; Seward, E; Wheeldon, A | 1 |
| Brown, MA; Cash, TF | 1 |
| Frizelle, HP; Moriarty, DC; O'Connor, JJ | 1 |
| Dach, F; Eckeli, AL; Rodrigues, AL | 1 |
| Diaz, J; Lammers, CH; Schwartz, JC; Sokoloff, P | 1 |
| Tanum, L | 1 |
| Greenawald, MH; Tyra, JM | 1 |
| Schatzberg, AF | 1 |
| Aguerre, S; Chaouloff, F; Combourieu, I; Durand, M; Edno, L; Fernandez, F; Mormède, P | 1 |
| Hatsuda, S; Hayashi, T; Kimura, H; Matsubara, M; Miura, K; Mori, T; Murakami, H; Ohara, M; Ohta, T; Sugita, S; Suzuki, S; Terashima, M | 1 |
| Judge, R; Montgomery, SA | 1 |
| Manev, H; Manev, R; Smalheiser, NR; Uz, T | 1 |
| Gembom, E; Lesch, KP; Mossner, R; Pan, Y; Peng, W; Simantov, R | 1 |
| Bosmans, E; Kenis, G; Kubera, M; Lin, AH; Maes, M; van Bockstaele, D | 1 |
| De Montis, MG; Gambarana, C; Scheggi, S; Tagliamonte, A; Tolu, P | 1 |
| Avitsur, R; Barak, O; Bette, M; Ovadia, H; Pollak, Y; Weidenfeld, J; Weihe, E; Yirmiya, R | 1 |
| Borsini, F; Brambilla, A; Cesana, R; Grippa, N | 1 |
| Limbird, LE; McDonald, MP; Schramm, NL | 1 |
| Emslie, GJ; Mayes, TL | 1 |
| De Montis, MG; Gambarana, C; Giachetti, D; Masi, F; Morazzoni, P; Rinaldi, M; Tolu, PL | 1 |
| Brattström, A; Käufeler, R; Meier, B | 1 |
| García-Colunga, J; López-Valdés, HE | 1 |
| Barros, SV; Nascimento, FC; Netto, CA; Silva, GR; Wyse, AT; Zanatta, LM; Zugno, AI | 1 |
| Bueno, L; Delvaux, M; Fioramonti, J; Frexinos, J | 1 |
| Alva, G; Arvanitis, LA; Carreon, D; Kalali, A; Potkin, SG; Thyrum, PT; Yeh, C | 1 |
| Griebel, G; Maffrand, JP; Pascal, M; Scatton, B; Serradeil-Le Gal, C; Simiand, J; Soubrie, P; Wagnon, J | 1 |
| Hashimoto, S; Hattori, T; Kawasaki, K; Kitamura, Y; Miki, N; Mochizuki, D; Otsuka, Y; Tsujita, R; Yamada, S | 1 |
| Li, H; Meller, E; Shen, C | 1 |
| Klein, DF; Quitkin, FM; Ross, DC | 1 |
| Diaz, A; Fouilloux, C; Ortiz, S | 1 |
| De La Garza, R; Jentsch, JD; Roth, RH; Verrico, CD | 1 |
| Agerman, K; Aloyz, R; Castrén, E; Ernfors, P; Haapasalo, A; Hendolin, P; Koponen, E; Lucas, G; MacDonald, E; Nawa, H; Saarelainen, T; Sairanen, M | 1 |
| Margolis, JM; Obach, RS | 1 |
| Abdel-Salam, OM; El-Shenawy, SM; Nofal, SM | 1 |
| Boyle, JP; Hillyer, JF; Yoshino, TP | 1 |
| Horschitz, S; Hummerich, R; Schloss, P | 1 |
| Calixto, JB; Lin, J; Rodrigues, AL; Rosa, AO; Santos, AR | 1 |
| Bianchi, M; Cavanni, P; Crespi, F; Faedo, S; Heidbreder, CA; Lacroix, LP; Perdona, E; Remelli, R | 1 |
| Jeenah, FY; Joffe, BI; Moosa, MY; Panz, VR | 1 |
| Abdel-Salam, OM; Arbid, MS; Baiuomy, AR | 1 |
| Butterweck, V; Simbrey, K; Winterhoff, H | 1 |
| Anjaneyulu, M; Chopra, K; Kaur, I | 1 |
| Basta-Kaim, A; Bosmans, E; Budziszewska, B; Kajta, M; Kenis, G; Kubera, M; Maes, M; Scharpe, S | 1 |
| Bateman, DN; Chick, J; Good, AM; Kelly, CA; Masterton, G | 1 |
| Burns, MP; Connor, TJ; Harkin, A; Kelly, JP | 1 |
| Brink, CB; de Kock, SE; Harvey, BH; Stein, DJ; Viljoen, SL | 1 |
| Dashti-Khavidaki, S; Ghaeli, P; Kamkar, MZ; Mesbahi, M; Sadeghi, M; Shahsavand, E | 1 |
| Bortolanza, LB; Calixto, JB; Campos, MM; Fernandes, ES; Ferreira, J; Santos, AR | 1 |
| Gower, AJ; Lamberty, Y | 1 |
| Barros, HM; Gomez, R; Kopittke, L | 1 |
| Calviño, MA; Iscla, IR; Szczupak, L | 1 |
| Blanco, G; Dempsey, CM; Gargus, A; Mackenzie, SM; Sze, JY | 1 |
| Agnati, L; Antonelli, T; Ferraro, L; Fuxe, K; Tanganelli, S; Tomasini, MC | 1 |
| Blackmon, CL; Nykamp, DL; Roberson, AG; Schmidt, PE | 1 |
| Castrén, E; Castrén, M; Ernfors, P; Lucas, G; Sairanen, M | 1 |
| Calabrese, F; Frasca, A; Fumagalli, F; Molteni, R; Racagni, G; Riva, MA | 1 |
| Davies, CA; Deliyannides, D; Klein, DF; McGrath, PJ; Quitkin, FM; Stewart, JW; Taylor, BP | 1 |
| Cimsit, M; Eroglu, L; Ozek, M; Sumen-Secgin, G | 1 |
| Holzer, CE; Meyer, WJ; Robert, R; Rosenberg, L; Rosenberg, M; Tcheung, WJ; Thomas, C; Villarreal, C | 1 |
| Brenneman, D; Crooke, J; Malatynska, E; Pinhasov, A; Rosenthal, D | 1 |
| Caramés, E; Gabarron, E; Garcia-Bayo, I; Haro, JM; Peñarrubia-Maria, MT; Pinto-Meza, A; Serrano-Blanco, A; Soler-Vila, M | 1 |
| Berton, O; Bolanos, CA; Dileone, RJ; Graham, D; Krishnan, V; McClung, CA; Monteggia, LM; Nestler, EJ; Renthal, W; Rios, M; Russo, SJ; Self, DW; Tsankova, NM | 1 |
| Che, W; Matsumoto, K; Min-Wei, W; Murakami, Y; Song, L | 1 |
| Dhingra, D; Sharma, A | 1 |
| Higuchi, T; Honda, K; Kamijima, K; Kitahara, S; Tanaka, S; Yamada, M | 1 |
| Cano, E; Fraiz, N; Orallo, F; Yáñez, M | 1 |
| Alenezi, AM; BaHammam, AS | 1 |
| Bresnick, MG; Kim, TJ; Magyar-Russell, G; Thombs, BD | 1 |
| Alonso, R; Avenet, P; Bergis, O; Cohen, C; Decobert, M; Françon, D; Griebel, G; Keane, P; le Fur, G; Lopez-Grancha, M; Pichat, P; Santucci, V; Scatton, B; Stahl, SM; Stemmelin, J; Terranova, JP | 1 |
| Guo, B; He, MM; Li, C; Liu, H; Shen, H; Wang, L; Wrighton, SA | 1 |
| Hallifax, D; Houston, JB | 1 |
| Airan, RD; Chen, H; Deisseroth, K; Gong, Y; Meltzer, LA; Roy, M | 1 |
| Higashi, M; Hitoshi, S; Ikenaka, K; Kato, N; Kumar, A; Maruta, N | 1 |
| Hay-Schmidt, A; Larsen, MH; Mikkelsen, JD; Rønn, LC | 1 |
| Parry, BL | 1 |
| Bylund, DB; Happe, HK; Petty, F; Reed, AL | 1 |
| Duszyk, S; Gruszczynski, W; Kocur, J; Rydzynski, Z; Trendak, W | 1 |
| Hutson, PH; Murray, F; Smith, DW | 1 |
| Cheng, XM; Shen, JS; Wang, ZT; Wei, XH | 1 |
| Harvey, I; Lilford, R; Song, F | 1 |
| Acevedo, EO; Huang, CJ; Sufka, KJ; Warnick, JE | 1 |
| Belzung, C; Surget, A; Yalcin, I | 1 |
| Bobadilla Lugo, RA; Pérez-Alvarez, V; Sánchez-Ortiz, R | 1 |
| Holzer, C; Meyer, WJ; Mitchell, C; Robert, R; Rosenberg, L; Rosenberg, M; Tcheung, WJ; Thomas, C; Villarreal, C | 1 |
| Almeida, OF; Bessa, JM; Cerqueira, JJ; Ferreira, D; Marques, F; Melo, I; Palha, JA; Sousa, N | 1 |
| Baker, KB; Davis, KW; Gerhardt, B; Lanthorn, TH; Malbari, MM; Mason, SS; Pogorelov, VM; Ritter, R; Savelieva, KV; Wray, SP | 1 |
| Acco, B; de Carvalho-Netto, EF; Gomes, KS; Monte, KC; Nogueira, PJ; Nunes-de-Souza, RL | 1 |
| Haro, JM; Peñarrubia, MT; Pinto-Meza, A; Serrano-Blanco, A; Suárez, D | 1 |
| Aburakawa, Y; Aizawa, H; Hasebe, N; Kwak, S; Sawada, J; Yamashita, T | 1 |
| Bogo, MR; Bonan, CD; Cognato, Gde P; Henz, SL; Sarkis, JJ; Vuaden, FC | 1 |
| Castagné, V; Moser, P; Porsolt, RD | 1 |
| Forrest, LR; Rudnick, G; Tavoulari, S | 1 |
| Birowo, P; Jonas, U; Kedia, GT; Kuczyk, MA; Meyer, M; Rahardjo, D; Scheller, F; Taher, A; Uckert, S | 1 |
| Borato, CE; Costa, AM; Esteves, A; Swerts, CA; Swerts, MS | 1 |
| Allen, KE; Babu, KN; Hanson, KL; Kunze, KL; Nelson, WL; VandenBrink, BM | 1 |
| Kenchaiah, BK; Kumar, S; Tharyan, P | 1 |
| Arias, HR; Feuerbach, D; Jozwiak, K; Russell, M; Targowska-Duda, KM | 1 |
| De Diego, M; Fierro, R; Godoy, CG; Mennickent, S; Vega, M | 1 |
| Fisar, Z; Hroudová, J; Raboch, J | 1 |
| Fiserová, A; Kovaru, F; Kovárů, H; Lisá, V; Ondráčkova, P | 1 |
| Vicente, MA; Zangrossi, H | 2 |
| Crespi, F | 1 |
| Hess, M; Höfner, G; Wanner, KT | 1 |
| Rushlow, WJ; Sutton, LP | 1 |
| Chesnokova, V; Cosgayon, R; Farrokhi, C; Lacayo, L; Pechnick, RN; Wawrowsky, K; Zonis, S | 1 |
| Araujo Escalona, AG; Estrada-Reyes, R; Heinze, G; Ledesma Velázquez, I; Martínez-Mota, L; Martínez-Vázquez, M; Moreno, J | 1 |
| Costentin, J; Do Rego, JC; Müller, LG; Nunes, JM; Rates, SM; Stein, AC; Stolz, ED; Viana, AF; von Poser, GL | 1 |
| Furutani, K; Inanobe, A; Kurachi, Y; Ohno, Y; Yamakawa, Y | 1 |
| Abbas, G; Dar, A; Naqvi, S | 1 |
| Banasr, M; Duman, RS; Duric, V; Elsayed, M; Fournier, NM; Licznerski, P | 1 |
| Cohn, DW; Kinoshita, D; Palermo-Neto, J | 1 |
| Chen, C; Du, X; Li, J; O'Donnell, JM; Pan, J; Ruan, L; Sun, J; Wang, R; Xu, Y; Yu, Y; Zhang, L | 1 |
| Bacci, A; Méndez, P; Pazienti, A; Szabó, G | 1 |
| Amaral, VC; Campos, KF; Miguel, TT; Nunes-de-Souza, RL; Rico, JL | 1 |
| Almeida, OF; Alves, ND; Bessa, JM; Mateus-Pinheiro, A; Monteiro, S; Morais, M; Patrício, P; Pinto, L; Sousa, N | 1 |
| Gao, J; Huang, X; Luan, L; Pickard, GE; Pu, M; Ren, C; So, KF; Wu, X; Wui-Man Lau, B; Yang, J; Zhou, Y | 1 |
| Aswar, UM; Bhosale, SH; Bodhankar, SL; Kalshetti, PP; Shelke, SM | 1 |
| Bohner, LO; Costa, AP; De Lima, TC; Lino-de-Oliveira, C; Santos, EC; Silva, CF; Vieira, C | 1 |
| Almeida, OF; Bessa, JM; Marques, F; Morais, M; Palha, JA; Pinto, L; Sousa, N | 1 |
| Bagmetova, VV; Berestovitskaia, VM; Chernysheva, IuV; Merkushenkova, OV; Tiurenkov, IN | 1 |
| de Bortoli, VC; Yamashita, PS; Zangrossi, H | 1 |
| Gouda, H; Handa, K; Hirono, S; Nakagome, I; Yamaotsu, N | 1 |
| Clarke, G; Cryan, JF; Dinan, TG; Griffin, BT; O'Brien, FE | 1 |
| Cadeddu, R; Carboni, E; Ibba, M; Sadile, A | 1 |
| Cho, HY; Kim, JE; Kim, YH; Lee, BJ; Lee, CH; Lee, JG; Park, SW; Seo, MK; Seol, W | 1 |
| Aitchison, KJ; Basu, A; Fernandes, C; Moran-Gates, T; Sugden, K; Tarazi, FI; Tsapakis, EM | 1 |
| Dean, B; Everall, I; Gibbons, A; Jeon, WJ; Scarr, E; Seo, MS; Tawadros, N | 1 |
| Bum, EN; Moto, FC; Ngoupaye, GT; Taiwe, GS; Talla, E | 1 |
| Cavender, HM; Cooke, JD; Grover, LM; Lima, HK | 1 |
| Bielecka, AM; Kowalski, J; Obuchowicz, E; Paul-Samojedny, M; Pudełko, A | 1 |
| Costa, EA; Da Rocha, FF; Fajemiroye, JO; Florentino, IF; Galdino, PM; Ghedini, PC; Polepally, PR; Zjawiony, JK | 1 |
| Berghauzen-Maciejewska, K; Dziubina, A; Głowacka, U; Kolasiewicz, W; Kuter, K; Ossowska, K; Wardas, J | 1 |
| Chen, L; Guan, XT; Shao, F; Wang, W; Xie, X | 1 |
| Almeida, OF; Alves, ND; Beckers, J; Bessa, JM; Correia, JS; Irmler, M; Korostynski, M; Machado-Santos, AR; Mateus-Pinheiro, A; Morais, M; Patrício, P; Piechota, M; Pinto, L; Sousa, N; Stoffel, R | 1 |
| Calabrese, B; Halpain, S | 1 |
| Dudka, J; Kasperek, R; Nowak, G; Poleszak, E; Serefko, A; Wlaź, A; Wlaź, P; Wośko, S; Wróbel, A | 1 |
| dos Santos, J; dos Santos, TS; Lino de Oliveira, C; Marcon, JC; Possamai, F; Walber, T | 1 |
| Akena, D; Aunon, F; Musisi, S; Nakasujja, N; Ngo, VK; Wagner, GJ | 1 |
| Leal, RB; Lopes, MW; Manosso, LM; Moretti, M; Neis, VB; Rodrigues, AL | 1 |
| De Montis, MG; Ferrari, A; Gambarana, C; Pelliccia, T; Scheggi, S | 1 |
| Aboul-Fotouh, S; El-Gayar, N; Habib, M; Shaker, S | 1 |
| Gold, PW; Goldstein, SA; Kling, MA; Licinio, J; Michelson, D; Mouro, CM; Pavlatou, MG; Wong, ML | 1 |
| Dalla, C; Ferreira, C; Kokras, N; Melo, A; Pêgo, JM; Sousa, N; Ventura-Silva, AP | 1 |
| Baik, HJ; Chung, RK; Kim, DY; Lee, GY; Park, HJ; Woo, JH; Zuo, Z | 1 |
| Beltran, E; Domínguez-Andrés, J; Erburu, M; Mai, A; Muñoz-Cobo, I; Puerta, E; Suzuki, T; Tordera, RM; Valente, S | 1 |
| Dean, B; Gibbons, AS; Jeon, WJ; Scarr, E | 1 |
| Dean, B; Gibbons, A; Hopper, S; McOmish, CE; Pavey, G; Scarr, E; Udawela, M | 1 |
| Ji, L; Li, H; Liu, W; Wang, Y | 1 |
| Harro, J; Kõiv, K; O'Leary, A; Raudkivi, K | 1 |
| Oniszczuk, A; Poleszak, E; Serefko, A; Stasiuk, W; Świąder, K; Szopa, A; Wlaź, P; Wośko, S; Wyska, E | 1 |
| Bagmetova, VV; Chernysheva, YV; Ozerov, AA; Tyurenkov, IN | 1 |
| Bryk, A; Bryniarski, P; Filipczak-Bryniarska, I; Kozlowski, M; Kuszmiersz, P; Myszka, M; Nazimek, K; Nowakowski, J; Strobel, S; Tyszka, A | 1 |
| Poleszak, E; Rechberger, T; Serefko, A; Wróbel, A | 1 |
| Bi, K; Jia, Y; Liao, Z; Liu, Z; Wu, B; Xu, M; Yan, T; Zhao, X | 1 |
| Cipriani, A; Coghill, D; Cohen, D; Cuijpers, P; Del Giovane, C; Hazell, P; Hetrick, SE; Leucht, S; Liu, L; Liu, Y; Michael, KD; Pu, J; Qin, B; Ravindran, AV; Whittington, C; Xie, P; Yang, L; Zhang, Y; Zhou, X | 1 |
| Bielecka, AM; Obuchowicz, E | 1 |
| Basta-Kaim, A; Budziszewska, B; Chamera, K; Głombik, K; Lasoń, W; Ślusarczyk, J; Trojan, E | 1 |
| Alves, ND; Bessa, JM; Correia, JS; Loureiro-Campos, E; Machado-Santos, AR; Mateus-Pinheiro, A; Morais, M; Patrício, P; Pinto, L; Sousa, N | 1 |
| Basta-Kaim, A; Budziszewska, B; Chamera, K; Głombik, K; Lasoń, W; Olszanecki, R; Ślusarczyk, J; Stachowicz, A; Suski, M; Trojan, E | 1 |
| Basta-Kaim, A; Chamera, K; Głombik, K; Kotarska, K; Olszanecki, R; Ślusarczyk, J; Stachowicz, A; Suski, M; Trojan, E | 1 |
| Cirilli, R; Erburu, MM; Mai, A; Muñoz-Cobo, I; Puerta, E; Tordera, RM; Valente, S; Zwergel, C | 1 |
| Gmeiner, P; Gulbins, E; Kornhuber, J; Löber, S; Rhein, C; Tripal, P | 1 |
| Guo, D; Guo, J; Huang, S; Li, Q; Polli, JE; Shu, Y; Xiong, Z; Ye, Z; Zhang, W; Zhou, H; Zhu, P | 1 |
| Ishibashi, T; Iwadate, R; Kawai, H; Kawashima, Y; Kudo, N; Mitsumoto, A | 1 |
| Badura, J; Chelminiak, Z; Cuprys, M; Fraczek, J; Koszla, O; Koziorowski, M; Mytych, J; Solek, P; Tabecka-Lonczynska, A | 1 |
| Dias, CAGM; Gouveia, A; Maximino, C; Santos, BRD; Santos, RCD | 1 |
| Bolding, IJ; Boone, DR; Cardenas, C; DeWitt, DS; Falduto, MT; Hellmich, HL; Micci, MA; Prough, DS; Sell, SL; Torres, KEO; Weisz, HA; Willey, HE | 1 |
| Audi, EA; de Souza Fiaes, GC; Graeff, FG; Maraschin, JC; Roncon, CM; Sestile, CC; Yabiku, CT; Zangrossi, H | 1 |
| Andrade, CH; Barbosa-Filho, JM; Capibaribe, VC; Carvalho, AMR; Chaves Filho, AJM; Chaves, RC; Fonteles, MMF; Gutierrez, SJC; Macedo, DS; Mallman, ASV; Mottin, M; Oliveira, ICM; Oliveira, NF; Rebouças, MO; Sartori, DP; Silva, DMA; Sousa, FCF; Valentim, JT | 1 |
| Cao, Y; Che, F; He, W; Sun, H; Wang, Y; Yao, Z; Zhang, H | 1 |
| Antonio, CB; Barbosa, AR; Borsoi, M; Lima, MS; Medeiros, I; Neves, GA; Nunes, LED; Pranke, MA; Rates, SMK | 1 |
| Chmielarz, P; Chorązka, K; Kowalska, M; Kuśmierczyk, J; Nalepa, I; Rafa-Zabłocka, K; Satała, G | 1 |
| Aoki, K; Matsuda, Y; Nihonmatsu-Kikuchi, N; Ozawa, N; Shinba, T; Shinozaki, T; Tatebayashi, Y | 1 |
| Koziorowski, M; Mytych, J; Sołek, P; Tabęcka-Łonczyńska, A | 1 |
| Ahmed, AS; Behl, T; Bhatt, S; Chigurupati, S; Gari, SBV; Sehgal, A; Sharma, N; Singh, S | 1 |
| Joca, SRL; Lisboa, SF; Sartim, AG; Silveira, KM; Vieira, L; Wegener, G | 1 |
| Cao, Q; Rao, Y; Yang, R; Zhao, J | 1 |
| Arikawe, AP; Costa, EA; Costa, RF; Fajemiroye, JO; Moreira, CVL; Napolitano, HB; Oliveira-Silva, I; Pedrino, GR; Prado, CC; Rodrigues, ACC; Silva, LSB; Silva, ON | 1 |
26 review(s) available for imipramine and fluoxetine
| Article | Year |
|---|---|
The role of receptor binding in drug discovery.
Topics: Animals; Drug Design; Humans; Receptors, Drug | 1993 |
Polypharmacology - foe or friend?
Topics: Animals; Communicable Diseases; Drug Evaluation, Preclinical; Drug Repositioning; Humans; Polypharmacology; Safety | 2013 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Small Molecules Selectively Targeting Sigma-1 Receptor for the Treatment of Neurological Diseases.
Topics: Allosteric Regulation; Clinical Trials as Topic; Humans; Ligands; Nervous System Diseases; Piperidines; Receptors, sigma; Sigma-1 Receptor; Small Molecule Libraries | 2020 |
Melancholic/endogenous depression and response to somatic treatment and placebo.
Topics: Antidepressive Agents; Depressive Disorder; Double-Blind Method; Fluoxetine; Humans; Imipramine; Oximes; Paroxetine; Piperidines; Placebos; Prospective Studies; Psychiatric Status Rating Scales; Treatment Outcome | 1992 |
The pharmacotherapy of minor depression.
Topics: Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Imipramine; Male; Monoamine Oxidase Inhibitors; Placebos | 1992 |
The emergence of suicidal ideation and behavior during antidepressant pharmacotherapy.
Topics: Antidepressive Agents; Depressive Disorder; Desipramine; Drug Therapy, Combination; Fluoxetine; Fluvoxamine; Humans; Imipramine; Mianserin; Suicide | 1991 |
The changing horizon in the treatment of depression: scientific/clinical publication overview.
Topics: Adolescent; Ambulatory Care; Antidepressive Agents; Anxiety Disorders; Clinical Trials as Topic; Depressive Disorder; Feeding and Eating Disorders; Fluoxetine; Humans; Imipramine; Obsessive-Compulsive Disorder; Panic; Placebos | 1991 |
Depression and selective serotonin reuptake inhibitors.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depression; Fluoxetine; Humans; Imipramine; Meta-Analysis as Topic; Middle Aged; Multicenter Studies as Topic; Paroxetine; Piperidines; Serotonin Antagonists | 1990 |
Therapeutic effects of serotonin uptake inhibitors in depression.
Topics: 5-Hydroxytryptophan; Alanine; Citalopram; Depressive Disorder; Fluoxetine; Fluvoxamine; Humans; Imipramine; Oximes; Paroxetine; Piperidines; Propylamines; Serotonin; Serotonin Antagonists; Trazodone; Zimeldine | 1986 |
Psychopharmacology in child and adolescent psychiatry: a review of the past seven years. Part II.
Topics: Adolescent; Alprazolam; Anticonvulsants; Antipsychotic Agents; Anxiety, Separation; Bipolar Disorder; Carbamazepine; Child; Child Behavior Disorders; Child, Preschool; Clonidine; Clozapine; Depressive Disorder; Dose-Response Relationship, Drug; Feeding and Eating Disorders; Fluoxetine; Humans; Imipramine; Lithium; Mutism; Obsessive-Compulsive Disorder; Phenobarbital; Phenytoin; Phobic Disorders; Schizophrenia; Sleep Wake Disorders; Tranquilizing Agents | 1995 |
Comparison of the tolerability of bupropion, fluoxetine, imipramine, nefazodone, paroxetine, sertraline, and venlafaxine.
Topics: 1-Naphthylamine; Antidepressive Agents; Bupropion; Clinical Trials as Topic; Cyclohexanols; Depressive Disorder; Drug Design; Drug Tolerance; Drugs, Investigational; Fluoxetine; Humans; Imipramine; Paroxetine; Piperazines; Selective Serotonin Reuptake Inhibitors; Sertraline; Triazoles; Venlafaxine Hydrochloride | 1995 |
Guidelines for the long-term treatment of depression.
Topics: Adult; Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Combined Modality Therapy; Depressive Disorder; Drug Administration Schedule; Female; Fluoxetine; Follow-Up Studies; Humans; Imipramine; Middle Aged; Paroxetine; Placebos; Psychotherapy; Recurrence; Time Factors; Treatment Outcome | 1994 |
Atypical antidepressants versus imipramine in the treatment of major depression: a meta-analysis.
Topics: Antidepressive Agents; Bupropion; Depressive Disorder; Fluoxetine; Humans; Imipramine; Trazodone | 1993 |
Management of recurrent depression.
Topics: 1-Naphthylamine; Antidepressive Agents; Chronic Disease; Combined Modality Therapy; Depressive Disorder; Drug Administration Schedule; Fluoxetine; Humans; Imipramine; Paroxetine; Psychotherapy; Recurrence; Sertraline | 1993 |
The safety profile of nefazodone.
Topics: Adolescent; Adult; Age Factors; Aged; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Depressive Disorder; Double-Blind Method; Drug Interactions; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Mixed Function Oxygenases; Piperazines; Placebos; Sexual Dysfunctions, Psychological; Treatment Outcome; Triazoles; Weight Gain | 1996 |
Special feature: personality disorders: models for treatment and strategies for treatment development.
Topics: Adult; Behavior Therapy; Clinical Protocols; Clinical Trials as Topic; Cognitive Behavioral Therapy; Combined Modality Therapy; Comorbidity; Evaluation Studies as Topic; Fluoxetine; Humans; Imipramine; Models, Psychological; Personality Disorders; Psychopharmacology; Psychotropic Drugs; Terminology as Topic | 1997 |
Depression and dementia: comorbidities, identification, and treatment.
Topics: Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Benzamides; Citalopram; Clomipramine; Cognition Disorders; Comorbidity; Dementia; Depression; Female; Fluoxetine; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Neuropsychological Tests; Nortriptyline; Selective Serotonin Reuptake Inhibitors; Sertraline | 1998 |
Reboxetine: tolerability and safety profile in patients with major depression.
Topics: Adrenergic Uptake Inhibitors; Age Factors; Antidepressive Agents; Cytochrome P-450 Enzyme System; Depressive Disorder, Major; Drug Interactions; Fluoxetine; Humans; Imipramine; Morpholines; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Reboxetine; Therapeutic Equivalency | 2000 |
Clinical efficacy of reboxetine in major depression.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents, Tricyclic; Controlled Clinical Trials as Topic; Depressive Disorder; Fluoxetine; Humans; Imipramine; Morpholines; Norepinephrine; Panic Disorder; Placebos; Reboxetine; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 2000 |
Efficacy and tolerability of Ze 117 St. John's wort extract in comparison with placebo, imipramine and fluoxetine for the treatment of mild to moderate depression according to ICD-10. An overview.
Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depression; Fluoxetine; Humans; Hypericum; Imipramine; Placebos; Plant Extracts; Randomized Controlled Trials as Topic | 2001 |
[Old and new physiopathological concepts of irritable bowel syndrome].
Topics: Adult; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Benzyl Compounds; Biopsy; Colon; Colonic Diseases, Functional; Diarrhea; Electromyography; Female; Fluoxetine; Food Hypersensitivity; Gastrointestinal Motility; Guinea Pigs; Humans; Ileum; Imipramine; Inflammation; Male; Mental Disorders; Propylamines; Psychotherapy; Psychotropic Drugs; Rats; Selective Serotonin Reuptake Inhibitors; Sex Offenses; Time Factors | 2001 |
Perimenopausal depression.
Topics: Administration, Cutaneous; Combined Modality Therapy; Comorbidity; Depression, Postpartum; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Estrogen Replacement Therapy; Ethinyl Estradiol; Female; Fluoxetine; Humans; Imipramine; Middle Aged; Perimenopause; Progesterone; Psychiatric Status Rating Scales; Terminology as Topic; Treatment Outcome | 2008 |
Adjusted indirect comparison may be less biased than direct comparison for evaluating new pharmaceutical interventions.
Topics: Antidepressive Agents, Second-Generation; Antipsychotic Agents; Bias; Bupropion; Data Interpretation, Statistical; Drug Therapy; Fluoxetine; Haloperidol; Humans; Imipramine; Meta-Analysis as Topic; Nicotine; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Smoking Cessation; Treatment Outcome | 2008 |
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.
Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Confounding Factors, Epidemiologic; Depressive Disorder, Major; Desipramine; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Evidence-Based Medicine; Fluoxetine; Humans; Imipramine; Mianserin; Mirtazapine; Nortriptyline; Paroxetine; Piperazines; Randomized Controlled Trials as Topic; Research Design; Sertraline; Treatment Outcome; Triazoles; Venlafaxine Hydrochloride | 2016 |
Efficacy and tolerability of antidepressant drugs in treatment of depression in children and adolescents: a network meta-analysis.
Topics: Adolescent; Amitriptyline; Antidepressive Agents; Child; Depression; Depressive Disorder, Major; Duloxetine Hydrochloride; Escitalopram; Fluoxetine; Humans; Imipramine; Network Meta-Analysis; Paroxetine; Sertraline; Venlafaxine Hydrochloride | 2022 |
44 trial(s) available for imipramine and fluoxetine
| Article | Year |
|---|---|
Sociotropy and autonomy: relationship to antidepressant drug treatment response and endogenous-nonendogenous dichotomy.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Imipramine; Individuality; Internal-External Control; Interpersonal Relations; Male; Oximes; Paroxetine; Piperidines; Serotonin Antagonists | 1992 |
Melancholic/endogenous depression and response to somatic treatment and placebo.
Topics: Antidepressive Agents; Depressive Disorder; Double-Blind Method; Fluoxetine; Humans; Imipramine; Oximes; Paroxetine; Piperidines; Placebos; Prospective Studies; Psychiatric Status Rating Scales; Treatment Outcome | 1992 |
A double-blind parallel study comparing fluoxetine with imipramine in the treatment of atypical depression.
Topics: Adult; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Imipramine; Male; Personality Inventory | 1991 |
High-dose fluoxetine: efficacy and activating-sedating effects in agitated and retarded depression.
Topics: Adolescent; Adult; Aged; Depression; Drug Administration Schedule; Female; Fluoxetine; Humans; Hypnotics and Sedatives; Imipramine; Male; Middle Aged; Psychiatric Status Rating Scales; Psychomotor Agitation; Psychomotor Performance | 1991 |
A comparison of fluoxetine imipramine and placebo in patients with bipolar depressive disorder.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Imipramine; Lithium; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Random Allocation | 1989 |
A comparative trial of a new antidepressant, fluoxetine.
Topics: Clinical Trials as Topic; Double-Blind Method; Fluoxetine; Humans; Imipramine; Personality Inventory; Psychiatric Status Rating Scales | 1989 |
A double-blind comparison of fluoxetine, imipramine and placebo in outpatients with major depression.
Topics: Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Psychological Tests; Random Allocation | 1989 |
Response to alternative antidepressants in imipramine nonresponders with bulimia nervosa.
Topics: Adolescent; Adult; Antidepressive Agents; Bulimia; Clinical Trials as Topic; Desipramine; Feeding Behavior; Female; Fluoxetine; Humans; Imipramine; Monoamine Oxidase Inhibitors; Nortriptyline; Random Allocation | 1989 |
The introductory placebo washout: a retrospective evaluation.
Topics: Clinical Trials as Topic; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Fluoxetine; Humans; Imipramine; Placebo Effect; Psychiatric Status Rating Scales | 1989 |
A double-blind study of fluoxetine and imipramine in major depression.
Topics: Depressive Disorder; Double-Blind Method; Fluoxetine; Humans; Imipramine | 1989 |
Fluoxetine versus imipramine.
Topics: Depressive Disorder; Double-Blind Method; Fluoxetine; Humans; Imipramine; Random Allocation | 1989 |
Placebo response in depression: a search for predictors.
Topics: Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Placebos; Prognosis; Psychiatric Status Rating Scales; Random Allocation | 1988 |
Fluoxetine, a selective serotonin uptake inhibitor, for the treatment of outpatients with major depression.
Topics: Adult; Ambulatory Care; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Propylamines; Random Allocation | 1988 |
Effects of antidepressants on thinking styles in depressed inpatients.
Topics: Adult; Antidepressive Agents; Clinical Trials as Topic; Cognition; Female; Fluoxetine; Humans; Imipramine; Male; Mood Disorders; Personality Tests; Thinking; Trazodone | 1988 |
A comparative trial of a new antidepressant, fluoxetine.
Topics: Adult; Aged; Body Weight; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Propylamines; Tremor | 1987 |
A comparison of fluoxetine, imipramine, and placebo in patients with major depressive disorder.
Topics: Adult; Ambulatory Care; Anxiety; Body Weight; Clinical Trials as Topic; Depressive Disorder; Dizziness; Double-Blind Method; Electrocardiography; Female; Fluoxetine; Heart; Humans; Hyperhidrosis; Imipramine; Male; Middle Aged; Patient Dropouts; Placebos; Propylamines; Psychiatric Status Rating Scales; Random Allocation; Sleep Initiation and Maintenance Disorders; Sleep Stages; Xerostomia | 1985 |
A review of multicenter controlled studies of fluoxetine vs. imipramine and placebo in outpatients with major depressive disorder.
Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Ambulatory Care; Anxiety; Clinical Trials as Topic; Depressive Disorder; Female; Fluoxetine; Headache; Humans; Hyperhidrosis; Imipramine; Male; Middle Aged; Patient Dropouts; Placebos; Propylamines; Psychiatric Status Rating Scales; Sleep Initiation and Maintenance Disorders; Sleep Stages | 1985 |
Characteristics of responders to fluoxetine.
Topics: Adult; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Imipramine; Male; Propylamines; Random Allocation | 1984 |
Fluoxetine in depressed patients: a comparison with imipramine.
Topics: Adult; Aged; Ambulatory Care; Body Weight; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Propylamines; Psychiatric Status Rating Scales; Random Allocation; Xerostomia | 1984 |
Fluoxetine in panic disorder: pharmacologic and tritiated platelet imipramine and paroxetine binding study.
Topics: Adolescent; Adult; Agoraphobia; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Panic Disorder; Paroxetine; Patient Dropouts; Prospective Studies; Psychiatric Status Rating Scales | 1995 |
Is baseline agitation a relative contraindication for a selective serotonin reuptake inhibitor: a comparative trial of fluoxetine versus imipramine.
Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Contraindications; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Personality Assessment; Personality Inventory; Psychomotor Agitation; Risk Factors; Treatment Outcome | 1994 |
Cost-effectiveness comparisons using "real world" randomized trials: the case of new antidepressant drugs.
Topics: Antidepressive Agents; Cost-Benefit Analysis; Desipramine; Drug Costs; Fluoxetine; Humans; Imipramine; Patient Compliance; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; United States | 1995 |
Childhood psychopathology retrospectively assessed among adults with early onset major depression.
Topics: 1-Naphthylamine; Adolescent; Adult; Anxiety Disorders; Child; Child Behavior Disorders; Comorbidity; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Imipramine; Male; Mental Disorders; Middle Aged; Paroxetine; Personality Development; Phobic Disorders; Recurrence; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Sertraline | 1994 |
Cognitive behavior therapy for treatment-refractory panic disorder.
Topics: Adult; Alprazolam; Clonazepam; Cognitive Behavioral Therapy; Combined Modality Therapy; Female; Fluoxetine; Follow-Up Studies; Humans; Imipramine; Male; Middle Aged; Panic Disorder; Pilot Projects; Psychiatric Status Rating Scales; Psychotherapy, Group; Treatment Outcome | 1994 |
Fluoxetine compared with imipramine in the treatment of inpatient depression. A multicenter trial.
Topics: Adolescent; Adult; Aged; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Hospitalization; Hospitals, Psychiatric; Humans; Imipramine; Male; Middle Aged; Treatment Outcome | 1993 |
A comparison of fluoxetine and imipramine in the treatment of outpatients with major depressive disorder.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Personality Inventory | 1993 |
Initial antidepressant choice in primary care. Effectiveness and cost of fluoxetine vs tricyclic antidepressants.
Topics: Adult; Aged; Analysis of Variance; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cost-Benefit Analysis; Desipramine; Drug Costs; Drug Utilization; Drug Utilization Review; Family Practice; Female; Fluoxetine; Health Maintenance Organizations; Humans; Imipramine; Male; Middle Aged; Outcome Assessment, Health Care; Psychiatric Status Rating Scales; Quality of Life; Washington | 1996 |
Is there a relationship between baseline and treatment-associated changes in [3H]-IMI platelet binding and clinical response in major depression?
Topics: Adolescent; Adult; Aged; Blood Platelets; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Imipramine; Kinetics; Male; Middle Aged; Radioligand Assay; Time Factors | 1996 |
Six month follow-up of early-onset chronic depression.
Topics: 1-Naphthylamine; Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Chronic Disease; Depressive Disorder; Drug Therapy, Combination; Female; Fluoxetine; Follow-Up Studies; Humans; Imipramine; Male; Middle Aged; Patient Discharge; Prognosis; Recurrence; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome | 1996 |
Antidepressant response follows an exponential decay curve: replication and extension.
Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depressive Disorder; Fluoxetine; Humans; Imipramine; Models, Statistical; Paroxetine; Personality Inventory; Psychometrics; Pyridazines; Treatment Outcome | 1997 |
Should anxiety and insomnia influence antidepressant selection: a randomized comparison of fluoxetine and imipramine.
Topics: Adult; Aged; Anxiety Disorders; Comorbidity; Depressive Disorder; Drug Administration Schedule; Female; Fluoxetine; Follow-Up Studies; Health Maintenance Organizations; Humans; Imipramine; Linear Models; Logistic Models; Male; Middle Aged; Personality Inventory; Primary Health Care; Probability; Psychiatric Status Rating Scales; Severity of Illness Index; Sleep Initiation and Maintenance Disorders; Treatment Outcome | 1998 |
The pharmacotherapy of depressive illness in adolescents: an open-label comparison of fluoxetine with imipramine-treated historical controls.
Topics: Adolescent; Age Factors; Antidepressive Agents, Second-Generation; Cohort Studies; Depressive Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluoxetine; Hospitalization; Humans; Imipramine; Male; Patient Dropouts; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Treatment Outcome | 1999 |
One year clinical and psychosocial outcomes of early-onset chronic depression.
Topics: Adult; Age Factors; Antidepressive Agents, Tricyclic; Chronic Disease; Depressive Disorder; Female; Fluoxetine; Follow-Up Studies; Humans; Imipramine; Male; Recurrence; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Social Adjustment; Social Support; Time Factors; Treatment Outcome | 1999 |
Do depressed subjects who have failed both fluoxetine and a tricyclic antidepressant respond to the combination?
Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Drug Therapy, Combination; Fluoxetine; Humans; Imipramine; Middle Aged; Personality Inventory; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 1999 |
A placebo-controlled study of fluoxetine versus imipramine in the acute treatment of atypical depression.
Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Female; Fluoxetine; Health Status; Humans; Imipramine; Male; Middle Aged; Patient Dropouts; Personality Inventory; Placebos; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Treatment Outcome | 2000 |
Attitudes about antidepressants: influence of information about weight-related side effects.
Topics: Adolescent; Adult; Antidepressive Agents; Attitude to Health; Body Weight; Drug Information Services; Female; Fluoxetine; Humans; Imipramine; Random Allocation; Sex Factors; Weight Gain; Weight Loss | 2000 |
Effect of fluoxetine and imipramine on the pharmacokinetics and tolerability of the antipsychotic quetiapine.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Bipolar Disorder; Dibenzothiazepines; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Fluoxetine; Humans; Imipramine; Male; Metabolic Clearance Rate; Middle Aged; Psychotic Disorders; Quetiapine Fumarate; Schizophrenia | 2002 |
Open trial study of a combined antidepressant (amitryptiline, perphenazine, diazepam) versus fluoxetine or imipramine in ambulatory depressed patients.
Topics: Adolescent; Adult; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Depressive Disorder; Diazepam; Drug Combinations; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Perphenazine; Prospective Studies; Psychiatric Status Rating Scales | 2002 |
African women with depression: the effect of imipramine and fluoxetine on body mass index and leptin secretion.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Black People; Body Mass Index; Depressive Disorder; Female; Fluoxetine; Humans; Imipramine; Leptin; South Africa | 2003 |
Comparing the effects of 8-week treatment with fluoxetine and imipramine on fasting blood glucose of patients with major depressive disorder.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Blood Glucose; Depressive Disorder, Major; Double-Blind Method; Fasting; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged | 2004 |
Remission rates with 3 consecutive antidepressant trials: effectiveness for depressed outpatients.
Topics: Adult; Ambulatory Care; Antidepressive Agents; Clinical Protocols; Depressive Disorder, Major; Double-Blind Method; Drug Administration Schedule; Female; Fluoxetine; Humans; Imipramine; Male; Patient Compliance; Placebos; Psychiatric Status Rating Scales; Pyrimidines; Secondary Prevention; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 2005 |
Effectiveness and cost-effectiveness of antidepressant treatment in primary health care: a six-month randomised study comparing fluoxetine to imipramine.
Topics: Adult; Antidepressive Agents, Tricyclic; Cost-Benefit Analysis; Depressive Disorder, Major; Double-Blind Method; Female; Fluoxetine; Follow-Up Studies; Humans; Imipramine; Male; Primary Health Care; Prospective Studies; Selective Serotonin Reuptake Inhibitors | 2006 |
Treating thermally injured children suffering symptoms of acute stress with imipramine and fluoxetine: a randomized, double-blind study.
Topics: Adrenergic Uptake Inhibitors; Burns; Child; Double-Blind Method; Drug Administration Schedule; Female; Fluoxetine; Humans; Imipramine; Male; Placebos; Prospective Studies; Psychiatric Status Rating Scales; Psychotherapy; Selective Serotonin Reuptake Inhibitors; Stress Disorders, Traumatic, Acute; Stress, Psychological; Treatment Outcome | 2008 |
Fluoxetine and imipramine: are there differences in cost-utility for depression in primary care?
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Costs and Cost Analysis; Depression; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Primary Health Care; Surveys and Questionnaires | 2009 |
310 other study(ies) available for imipramine and fluoxetine
| Article | Year |
|---|---|
Pyrroloisoquinoline antidepressants. 3. A focus on serotonin.
Topics: Animals; Antidepressive Agents; Biological Assay; Biological Transport; Dose-Response Relationship, Drug; Isoquinolines; Mice; Pyrroles; Rats; Serotonin; Structure-Activity Relationship | 1990 |
Pyrroloisoquinoline antidepressants. 2. In-depth exploration of structure-activity relationships.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain; Catecholamines; Chemical Phenomena; Chemistry; Dopamine; Isoquinolines; Male; Molecular Conformation; Motor Activity; Norepinephrine; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Structure-Activity Relationship; Synaptosomes; Tetrabenazine | 1987 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations | 2002 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
Psychopharmacological profile of the alkaloid psychollatine as a 5HT2A/C serotonin modulator.
Topics: Anti-Anxiety Agents; Brazil; Diazepam; Glycosides; Indole Alkaloids; Memory; Models, Biological; Molecular Structure; Monoterpenes; Plants, Medicinal; Psychopharmacology; Psychotria; Receptors, GABA-A; Receptors, Serotonin; Serotonin Receptor Agonists | 2005 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake.
Topics: Amino Acid Sequence; Animals; Antidepressive Agents, Tricyclic; Bacterial Proteins; Binding Sites; Caenorhabditis elegans Proteins; Cell Line; Conserved Sequence; Crystallography, X-Ray; Desipramine; Dopamine; Dopamine Uptake Inhibitors; Drosophila Proteins; Humans; Leucine; Models, Molecular; Molecular Sequence Data; Neurotransmitter Uptake Inhibitors; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Plasma Membrane Neurotransmitter Transport Proteins; Protein Binding; Protein Conformation; Selective Serotonin Reuptake Inhibitors; Sequence Homology, Amino Acid; Serotonin | 2007 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
An antidepressant that extends lifespan in adult Caenorhabditis elegans.
Topics: Aging; Animals; Antidepressive Agents; Caenorhabditis elegans; Caloric Restriction; Humans; Longevity; Methiothepin; Mianserin; Octopamine; Receptors, Biogenic Amine; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Starvation | 2007 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Molecular properties of psychopharmacological drugs determining non-competitive inhibition of 5-HT3A receptors.
Topics: Binding Sites; Computer Simulation; Databases, Factual; Models, Chemical; Models, Molecular; Molecular Structure; Molecular Weight; Psychotropic Drugs; Serotonin 5-HT3 Receptor Antagonists; Structure-Activity Relationship | 2009 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Synthesis, antidepressant evaluation and QSAR studies of novel 2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(substituted phenyl)acetamides.
Topics: Acetamides; Animals; Antidepressive Agents; Linear Models; Mice; Quantitative Structure-Activity Relationship | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results | 2011 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Discovery and synthesis of novel 3-phenylcoumarin derivatives as antidepressant agents.
Topics: Animals; Antidepressive Agents; Coumarins; Dose-Response Relationship, Drug; Drug Discovery; Male; Mice; Spectrophotometry, Infrared; Stress, Physiological; Swimming | 2011 |
Further structure-activity relationship studies on 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol: identification of compounds with triple uptake inhibitory activity as potential antidepressant agents.
Topics: Animals; Antidepressive Agents; Brain; Magnetic Resonance Spectroscopy; Neurotransmitter Uptake Inhibitors; Pyrans; Rats; Structure-Activity Relationship | 2011 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Synthesis and antidepressant-like activity evaluation of sulphonamides and sulphonyl-hydrazones.
Topics: Animals; Antidepressive Agents; Hydrazones; Male; Mice; Molecular Structure; Motor Activity; Stereoisomerism; Stress, Psychological; Sulfonamides; Swimming | 2011 |
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells).
Topics: Adrenergic beta-Antagonists; Amines; Ammonium Chloride; Antidepressive Agents, Tricyclic; Atorvastatin; Cell Line, Transformed; Diuretics; Hepatocytes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imipramine; Lysosomes; Monensin; Nigericin; Propranolol; Pyrroles | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Synthesis and biological evaluation of novel 3,4-diaryl lactam derivatives as triple reuptake inhibitors.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Lactams; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Pyrrolidinones; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins | 2013 |
2-Amino-6-chloro-3,4-dihydroquinazoline: A novel 5-HT3 receptor antagonist with antidepressant character.
Topics: Amination; Animals; Antidepressive Agents; Anura; Halogenation; Hindlimb Suspension; Mice; Quinazolines; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists | 2013 |
Design and synthesis of new series of coumarin-aminopyran derivatives possessing potential anti-depressant-like activity.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Coumarins; Depression; Dose-Response Relationship, Drug; Drug Design; Fluoxetine; Male; Mice; Models, Molecular; Molecular Structure; Motor Activity; Pyrans; Structure-Activity Relationship; Swimming | 2015 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Novel aryl piperazines for alleviation of 'andropause' associated prostatic disorders and depression.
Topics: Androgen Antagonists; Andropause; Animals; Cell Line; Depression; Down-Regulation; Humans; Male; Molecular Docking Simulation; Piperazine; Piperazines; Prostatic Diseases; Rats; Receptors, Androgen | 2017 |
Effects of fluoxetine and imipramine on male Schistosoma mansoni.
Topics: Animals; Benzodiazepinones; Calcium; Drug Interactions; Fluoxetine; Imipramine; Lanthanum; Male; Muscle Contraction; Potassium; Praziquantel; Propylamines; Schistosoma mansoni; Serotonin Antagonists | 1979 |
Action of serotoninmimetics in the behavioral despair test in rats.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Haloperidol; Imipramine; Immobilization; Lysergic Acid Diethylamide; Premedication; Quipazine; Rats; Receptors, Serotonin; Serotonin | 1979 |
Potentiation of 5-hydroxytryptamine-induced contraction in rat aorta by chlorpheniramine, citalopram and fluoxetine.
Topics: Animals; Aorta, Thoracic; Chlorpheniramine; Citalopram; Cocaine; Dose-Response Relationship, Drug; Fluoxetine; Histamine H1 Antagonists; Imipramine; In Vitro Techniques; Male; Pargyline; Rats; Rats, Sprague-Dawley; Serotonin; Vasoconstriction | 1992 |
The effect of antidepressant drugs on the locomotor hyperactivity induced by MK-801, a non-competitive NMDA receptor antagonist.
Topics: Animals; Antidepressive Agents; Benzazepines; Citalopram; Dizocilpine Maleate; Fluoxetine; Imipramine; Isomerism; Male; Maprotiline; Motor Activity; Prazosin; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Sulpiride | 1992 |
Tricyclic antidepressant plasma levels after fluoxetine addition.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged | 1992 |
Quantification and mechanism of the fluoxetine and tricyclic antidepressant interaction.
Topics: Adult; Desipramine; Drug Evaluation; Drug Interactions; Fluoxetine; Humans; Imipramine; Male; Middle Aged | 1992 |
Comment: fluoxetine adverse effects and drug interactions.
Topics: Adult; Depressive Disorder; Drug Interactions; Enalapril; Female; Fluoxetine; Humans; Imipramine | 1991 |
Cocaine-induced turning behavior in rats with 6-hydroxydopamine lesions: effect of transplants of fetal substantia nigra.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Diseases; Brain Tissue Transplantation; Cocaine; Dopamine; Fetal Tissue Transplantation; Fluoxetine; Imipramine; Male; Neural Pathways; Neurotransmitter Uptake Inhibitors; Nomifensine; Oxidopamine; Piperazines; Rats; Rats, Inbred Strains; Substantia Nigra | 1991 |
Fluoxetine and norfluoxetine are potent inhibitors of P450IID6--the source of the sparteine/debrisoquine oxidation polymorphism.
Topics: Fluoxetine; Humans; Imipramine; Microsomes, Liver; Polymorphism, Genetic | 1991 |
Association of fluoxetine with suicidal ideation.
Topics: Depressive Disorder; Desipramine; Drug Therapy, Combination; Fluoxetine; Humans; Imipramine; Suicide | 1991 |
The relationship between response to fluoxetine, plasma drug levels, imipramine binding to platelet membranes and whole-blood 5-HT.
Topics: Biomarkers; Biotransformation; Blood Platelets; Carrier Proteins; Cell Membrane; Depressive Disorder; Dexamethasone; Fluoxetine; Humans; Hydrocortisone; Imipramine; Receptors, Drug; Receptors, Neurotransmitter; Serotonin | 1990 |
Successful antidepressant treatment of nonparaphilic sexual addictions and paraphilias in men.
Topics: Adult; Antidepressive Agents; Depressive Disorder; Fluoxetine; Humans; Imipramine; Lithium; Male; Masturbation; Middle Aged; Paraphilic Disorders; Psychiatric Status Rating Scales; Sexual Behavior; Sexual Dysfunctions, Psychological; Trazodone | 1991 |
Fluoxetine-induced elevation and prolongation of tricyclic levels in overdose.
Topics: Antidepressive Agents, Tricyclic; Depressive Disorder; Drug Interactions; Drug Overdose; Drug Therapy, Combination; Female; Fluoxetine; Humans; Imipramine; Middle Aged; Stimulation, Chemical; Suicide, Attempted | 1991 |
[3H] sertraline binding to rat brain membranes.
Topics: 1-Naphthylamine; Animals; Brain; Fenclonine; Fluoxetine; Imipramine; In Vitro Techniques; Male; Membranes; Naphthalenes; Paroxetine; Piperidines; Rats; Receptors, Serotonin; Serotonin Antagonists; Sertraline | 1990 |
Neural adaptation in imipramine-treated rats processed in forced swim test: assessment of time course, handling, rat strain and amine uptake.
Topics: Adaptation, Physiological; Animals; Behavior, Animal; Cerebral Cortex; Corticosterone; Dihydroalprenolol; Fluoxetine; Hippocampus; Imipramine; Ketanserin; Male; Physical Exertion; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, GABA-A; Species Specificity; Swimming | 1990 |
GABA, depression and the mechanism of action of antidepressant drugs: a neuroendocrine approach.
Topics: Adult; Amitriptyline; Antidepressive Agents; Baclofen; Brain; Depressive Disorder; Fluoxetine; gamma-Aminobutyric Acid; Growth Hormone; Humans; Imipramine; Male; Middle Aged; Personality Tests; Receptors, GABA-A | 1990 |
Effects of fluoxetine treatment of platelet 3H-imipramine binding, 5-HT uptake and 5-HT content in major depressive disorder.
Topics: Adult; Aged; Blood Platelets; Carrier Proteins; Depressive Disorder; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Receptors, Drug; Receptors, Neurotransmitter; Serotonin | 1990 |
Depression in the context of human immunodeficiency virus infection: implications for treatment.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Antidepressive Agents; Depressive Disorder; Drug Evaluation; Fluoxetine; HIV Seropositivity; Humans; Imipramine; Male; Medical Records; Middle Aged; Retrospective Studies | 1990 |
A common binding site for tricyclic and nontricyclic 5-hydroxytryptamine uptake inhibitors at the substrate recognition site of the neuronal sodium-dependent 5-hydroxytryptamine transporter.
Topics: Animals; Antidepressive Agents, Tricyclic; Binding Sites; Binding, Competitive; Biological Transport; Cerebral Cortex; Citalopram; Dose-Response Relationship, Drug; Ethylmaleimide; Fluoxetine; Imipramine; Male; Neurons; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sodium | 1989 |
Pharmacological dissection of panic and depersonalization.
Topics: Adolescent; Alprazolam; Anxiety Disorders; Depersonalization; Fear; Female; Fluoxetine; Humans; Imipramine; Manuals as Topic; Panic | 1989 |
Fluoxetine in panic disorder patients with imipramine-associated weight gain.
Topics: Adult; Agoraphobia; Depressive Disorder; Fear; Female; Fluoxetine; Humans; Imipramine; Middle Aged; Panic; Phobic Disorders; Weight Gain | 1989 |
Effects of imipramine and serotonin-2 agonists and antagonists on serotonin-2 and beta-adrenergic receptors following noradrenergic or serotonergic denervation.
Topics: 5,7-Dihydroxytryptamine; Animals; Cerebral Cortex; Cerebral Ventricles; Fluoxetine; Imipramine; Ketanserin; Kinetics; Male; Neurons; Quinolines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reference Values; Serotonin; Stereotyped Behavior | 1989 |
Translocation of protein kinase C is associated with inhibition of 5-HT uptake by cultured endothelial cells.
Topics: Animals; Biological Transport; Cattle; Cell Membrane; Cells, Cultured; Cytosol; Endothelium, Vascular; Fluoxetine; Imipramine; Kinetics; Nigericin; Protein Kinase C; Pulmonary Artery; Serotonin; Tetradecanoylphorbol Acetate | 1989 |
Characterization of [3H]paroxetine binding in rat brain.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Cerebral Cortex; Citalopram; Fluoxetine; Imipramine; Male; Paroxetine; Peptide Hydrolases; Piperidines; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tritium | 1988 |
Quantitative autoradiography of serotonin uptake sites in rat brain using [3H]cyanoimipramine.
Topics: 1-Naphthylamine; Animals; Autoradiography; Binding, Competitive; Brain; Fluoxetine; Imipramine; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Sertraline; Zimeldine | 1988 |
Examination of the relationship between the uptake system for 5-hydroxytryptamine and the high-affinity [3H]imipramine binding site--I. Inhibition by drugs.
Topics: Animals; Carrier Proteins; Catecholamines; Cerebral Cortex; Energy Metabolism; Fluoxetine; Imipramine; In Vitro Techniques; Kinetics; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, Neurotransmitter; Serotonin; Synaptosomes; Zimeldine | 1986 |
Inhibition of sodium-dependent [3H]imipramine binding in rat brain by serotonin and serotonin uptake inhibitors.
Topics: Animals; Cell Membrane; Cerebral Cortex; Clomipramine; Fluoxetine; Imipramine; Male; Rats; Receptors, Serotonin; Serotonin; Sodium; Trazodone | 1988 |
Pharmaco-ethological analysis of antidepressant drug effects.
Topics: Aggression; Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Fluoxetine; Imipramine; Iproniazid; Male; Mice; Motor Activity; Reserpine; Social Behavior; Trazodone | 1986 |
Allosteric interaction between the site labeled by [3H]imipramine and the serotonin transporter in human platelets.
Topics: Amitriptyline; Blood Platelets; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorpromazine; Ethylmaleimide; Fluoxetine; Humans; Imipramine; Kinetics; Pyrilamine; Receptors, Serotonin | 1987 |
Chlorpromazine, other amphiphilic cationic drugs and praziquantel: effects on carbohydrate metabolism of Schistosoma mansoni.
Topics: Amitriptyline; Animals; Carbohydrate Metabolism; Chlorpromazine; Fluoxetine; Glucose; Imipramine; Lactates; Praziquantel; Propranolol; Schistosoma mansoni | 1987 |
Antipanic drug effects during lactate infusion in lactate-refractory panic patients.
Topics: Adult; Agoraphobia; Alprazolam; Clonidine; Desipramine; Fear; Female; Fluoxetine; Humans; Imipramine; Lactates; Lactic Acid; Male; Panic; Phobic Disorders; Psychological Tests; Psychotropic Drugs | 1987 |
Comparative trial of a new antidepressant.
Topics: Depressive Disorder; Fluoxetine; Humans; Imipramine | 1987 |
Tryptamine, a substrate for the serotonin transporter in human platelets, modifies the dissociation kinetics of [3H]imipramine binding: possible allosteric interaction.
Topics: Allosteric Regulation; Antidepressive Agents, Tricyclic; Blood Platelets; Carrier Proteins; Desipramine; Fluoxetine; Humans; Imipramine; Serotonin; Serotonin Antagonists; Tryptamines | 1985 |
Effect of fluoxetine on the electrocardiogram.
Topics: Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents; Arrhythmias, Cardiac; Bundle-Branch Block; Doxepin; Electrocardiography; Female; Fluoxetine; Heart; Heart Conduction System; Heart Rate; Humans; Imipramine; Male; Middle Aged; Propylamines; Retrospective Studies | 1985 |
Manipulations of 5-HT activity and memory in the rat.
Topics: 5-Hydroxytryptophan; Animals; Avoidance Learning; Drug Interactions; Fenfluramine; Fluoxetine; Imipramine; Lithium; Male; Memory; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tranylcypromine | 1985 |
5-Hydroxytryptamine uptake and imipramine binding sites in neurotumor NCB-20 cells.
Topics: Animals; Binding Sites; Brain; Clomipramine; Cricetinae; Cricetulus; Desipramine; Fluoxetine; Hybrid Cells; Imipramine; Iprindole; Kinetics; Mianserin; Neuroblastoma; Opipramol; Rats; Serotonin | 1985 |
Effects of subchronic administration of psychoactive substances on the circadian rhythm of urinary corticosterone excretion in rats.
Topics: Animals; Antidepressive Agents; Circadian Rhythm; Clorgyline; Corticosterone; Fluoxetine; Imipramine; Male; Maprotiline; Pargyline; Propylamines; Rats; Trimipramine | 1985 |
Withdrawal-like behaviour induced by inhibitors of biogenic amine reuptake in rats treated chronically with delta 9-tetrahydrocannabinol.
Topics: Animals; Biogenic Amines; Body Weight; Clomipramine; Dronabinol; Eating; Fluoxetine; Humans; Imipramine; Male; Rats; Substance Withdrawal Syndrome; Time Factors | 1980 |
Brain serotonin receptors and neuropsychiatric disorders.
Topics: Animals; Brain; Desipramine; Fluoxetine; Humans; Imipramine; Kinetics; Lysergic Acid Diethylamide; Mental Disorders; Organ Specificity; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Serotonin; Schizophrenia; Serotonin | 1981 |
Modulation of neuronal serotonin uptake by a putative endogenous ligand of imipramine recognition sites.
Topics: Animals; Axons; Biological Transport; Carrier Proteins; Fluoxetine; Hippocampus; Imipramine; Kinetics; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, Neurotransmitter; Serotonin; Synaptic Membranes | 1983 |
Involvement of the amygdala in the effect of antidepressants on the passive avoidance deficit in bulbectomised rats.
Topics: Amitriptyline; Amygdala; Animals; Antidepressive Agents; Avoidance Learning; Fluoxetine; Imipramine; Male; Metergoline; Norepinephrine; Olfactory Bulb; Rats; Serotonin | 1981 |
Antidepressants and the control of predatory behavior.
Topics: Animals; Appetitive Behavior; Clomipramine; Dose-Response Relationship, Drug; Ferrets; Fluoxetine; Imipramine; Male; Predatory Behavior; Propylamines; Reaction Time | 1980 |
Second generation antidepressants.
Topics: Antidepressive Agents, Tricyclic; Catecholamines; Depressive Disorder; Double-Blind Method; Fluoxetine; Humans; Imipramine; Monoamine Oxidase Inhibitors; Nomifensine; Serotonin; Trazodone | 1980 |
Serotonin-mimetic and antidepressant drugs on passive avoidance learning by olfactory bulbectomised rats.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Clonidine; Ergolines; Fenfluramine; Fluoxetine; Imipramine; Male; Metergoline; Mianserin; Olfactory Bulb; Quipazine; Rats; Serotonin; Serotonin Antagonists | 1980 |
The effects of acute and repeated treatment with salbutamol, a beta-adrenoceptor agonist, on clonidine-induced hypoactivity in rats.
Topics: Albuterol; Animals; Clonidine; Desipramine; Drug Interactions; Exploratory Behavior; Fluoxetine; Imipramine; Male; Propranolol; Rats; Rats, Inbred Strains; Yohimbine | 1982 |
Differential modulation of antipredator defensive behavior in Swiss-Webster mice following acute or chronic administration of imipramine and fluoxetine.
Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Fluoxetine; Imipramine; Male; Mice; Mice, Inbred Strains; Panic; Selective Serotonin Reuptake Inhibitors; Time Factors | 1995 |
The use of decision analysis in the pharmacoeconomic evaluation of an antidepressant: a cost-effectiveness study of nefazodone.
Topics: Antidepressive Agents; Cost-Benefit Analysis; Decision Support Techniques; Economics, Pharmaceutical; Fluoxetine; Follow-Up Studies; Humans; Imipramine; Models, Economic; Piperazines; Treatment Outcome; Triazoles | 1995 |
Behavioural profile of two potential antidepressant pyridazine derivatives including arylpiperazinyl moieties in their structure, in mice.
Topics: 5-Hydroxytryptophan; Analgesia; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Blepharoptosis; Citalopram; Clomipramine; Drug Interactions; Fluoxetine; Hypothermia; Imipramine; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Models, Molecular; Motor Activity; Naloxone; Piperazines; Pyridazines; Reserpine; Structure-Activity Relationship; Swimming; Trazodone; Yohimbine | 1995 |
Studies of reversible and selective inhibitors of monoamine oxidase A in dysthymia.
Topics: Benzamides; Depressive Disorder; Fluoxetine; Humans; Imipramine; Moclobemide; Monoamine Oxidase Inhibitors; Placebos; Treatment Outcome | 1995 |
Serotonin uptake inhibitors modulate intracellular Ca2+ mobilization in platelets.
Topics: 1-Naphthylamine; Blood Platelets; Calcium; Calmodulin; Cells, Cultured; Fluoxetine; Humans; Imipramine; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline | 1995 |
Up-regulation of beta 1-adrenergic receptors in rat brain after chronic citalopram and fluoxetine treatments.
Topics: Adrenergic beta-1 Receptor Agonists; Animals; Autoradiography; Brain Chemistry; Citalopram; Fluoxetine; Image Processing, Computer-Assisted; Imipramine; Iodocyanopindolol; Male; Pindolol; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Up-Regulation | 1994 |
In vivo biogenic amine efflux in medial prefrontal cortex with imipramine, fluoxetine, and fluvoxamine.
Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Fluoxetine; Fluvoxamine; Imipramine; Male; Microdialysis; Norepinephrine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Serotonin | 1994 |
Platelet 3H-paroxetine binding in control subjects and depressed patients: relationship to serotonin uptake and age.
Topics: Adult; Age Factors; Binding Sites; Blood Platelets; Depressive Disorder; Desipramine; Female; Fluoxetine; Humans; Imipramine; Infant; Male; Paroxetine; Serotonin | 1994 |
Augmentation strategies with tricyclic or fluoxetine treatment in seven partially responsive panic disorder patients.
Topics: Adult; Alprazolam; Antidepressive Agents, Tricyclic; Desipramine; Drug Therapy, Combination; Female; Fluoxetine; Humans; Imipramine; Lorazepam; Male; Panic Disorder; Retrospective Studies; Treatment Outcome | 1994 |
Nocturnal and circadian body temperatures of depressed outpatients during symptomatic and recovered states.
Topics: Adult; Analysis of Variance; Body Temperature; Circadian Rhythm; Depressive Disorder; Female; Fluoxetine; Humans; Imipramine; Male; Psychiatric Status Rating Scales; Psychotherapy | 1994 |
Cerebral flavin-containing monooxygenase-mediated metabolism of antidepressants in brain: immunochemical properties and immunocytochemical localization.
Topics: Animals; Antidepressive Agents; Blotting, Western; Brain; Cytochrome P-450 Enzyme System; Female; Flavoproteins; Fluoxetine; Imipramine; Immunohistochemistry; Kinetics; Male; Microsomes; Oxidation-Reduction; Rats; Rats, Wistar | 1993 |
Concurrent liquid chromatographic measurement of fluoxetine, amitriptyline, imipramine, and their active metabolites norfluoxetine, nortriptyline, and desipramine in plasma.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Desipramine; Fluoxetine; Humans; Imipramine; Indicators and Reagents; Nortriptyline; Spectrophotometry, Ultraviolet | 1993 |
Sexual dysfunction during antidepressant treatment.
Topics: Adult; Ambulatory Care; Antidepressive Agents; Anxiety Disorders; Clomipramine; Depressive Disorder; Female; Fluoxetine; Humans; Imipramine; Incidence; Male; Middle Aged; Orgasm; Pain; Patient Compliance; Retrospective Studies; Sexual Dysfunctions, Psychological | 1993 |
p-chlorophenylalanine-reversible reduction of sigma binding sites by chronic imipramine treatment in rat brain.
Topics: Animals; Biogenic Monoamines; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Desipramine; Fenclonine; Fluoxetine; Guanidines; Hippocampus; Imipramine; Kinetics; Male; Proteins; Rats; Rats, Wistar; Receptors, sigma; Serotonin | 1993 |
Regional brain expression of serotonin transporter mRNA and its regulation by reuptake inhibiting antidepressants.
Topics: Animals; Base Sequence; Brain Chemistry; Carrier Proteins; Clorgyline; Fluoxetine; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Monoamine Oxidase Inhibitors; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Piperazines; Raphe Nuclei; Rats; Rats, Wistar; RNA, Messenger; Serotonin; Serotonin Plasma Membrane Transport Proteins | 1993 |
Fluoxetine treatment of trichotillomania and depression in a prepubertal child.
Topics: Behavior Therapy; Child; Depressive Disorder; Fluoxetine; Humans; Imipramine; Male; Puberty; Trichotillomania | 1993 |
[3H]paroxetine binding and serotonin content of rat brain: absence of changes following antidepressant treatments.
Topics: Animals; Antidepressive Agents; Brain; Chromatography, High Pressure Liquid; Fluoxetine; Imipramine; Male; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Trimipramine | 1993 |
Effect of antidepressants on striatal and accumbens extracellular dopamine levels.
Topics: Animals; Antidepressive Agents; Clomipramine; Corpus Striatum; Dopamine; Fluoxetine; Imipramine; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Time Factors | 1995 |
Desensitization of the D1 dopamine receptors in rats reproduces a model of escape deficit reverted by imipramine, fluoxetine and clomipramine.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Clomipramine; Depression; Disease Models, Animal; Escape Reaction; Fluoxetine; Imipramine; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Time Factors | 1995 |
Pharmacological properties of 403U76, a new chemical class of 5-hydroxytryptamine- and noradrenaline-reuptake inhibitor.
Topics: 5-Hydroxytryptophan; Adrenergic Uptake Inhibitors; Animals; Animals, Newborn; Benzyl Alcohols; Binding, Competitive; Dogs; Electrophysiology; Fluoxetine; Fluvoxamine; Hemodynamics; Imipramine; Male; Mice; Neurons; Norepinephrine; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Species Specificity; Synaptic Transmission; Tetrabenazine; Vocalization, Animal | 1995 |
Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus.
Topics: 1-Naphthylamine; Animals; Antidepressive Agents; Base Sequence; Blotting, Northern; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Desipramine; Electric Stimulation; Fluoxetine; Hippocampus; Imipramine; In Situ Hybridization; Male; Molecular Sequence Data; Nerve Growth Factors; Nerve Tissue Proteins; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptor, trkB; Receptors, Nerve Growth Factor; RNA, Messenger; Rolipram; Sertraline; Time Factors; Tranylcypromine | 1996 |
Effects of long-term treatment with antidepressant drugs on proopiomelanocortin and neuropeptide Y mRNA expression in the hypothalamic arcuate nucleus of rats.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Arcuate Nucleus of Hypothalamus; Fluoxetine; Gene Expression; Idazoxan; Image Processing, Computer-Assisted; Imipramine; In Situ Hybridization; Male; Neuropeptide Y; Phenelzine; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors | 1996 |
Fluoxetine-imipramine interaction.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluoxetine; Humans; Imipramine; Lithium; Suicide Prevention | 1996 |
Antidepressant drugs given repeatedly change the binding of the dopamine D2 receptor agonist, [3H]N-0437, to dopamine D2 receptors in the rat brain.
Topics: Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Corpus Striatum; Dopamine Agonists; Fluoxetine; Imipramine; Limbic System; Male; Mianserin; Protein Binding; Rats; Rats, Wistar; Receptors, Dopamine D2; Synaptic Membranes; Tetrahydronaphthalenes; Thiophenes; Up-Regulation | 1996 |
In vivo effects of the simultaneous blockade of serotonin and norepinephrine transporters on serotonergic function. Microdialysis studies.
Topics: Adrenergic Uptake Inhibitors; Animals; Carrier Proteins; Cerebral Cortex; Citalopram; Clonidine; Desipramine; Fluoxetine; Fluvoxamine; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Raphe Nuclei; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters | 1996 |
Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Brain; Desipramine; Fluoxetine; Imipramine; Male; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Selective Serotonin Reuptake Inhibitors; Stereoisomerism | 1996 |
Effects of serotonergic agents on food-restriction-induced hyperactivity.
Topics: Animals; Antidepressive Agents, Tricyclic; Body Weight; Disease Models, Animal; Eating; Female; Fenclonine; Fluoxetine; Food Deprivation; Imipramine; Motor Activity; Obsessive-Compulsive Disorder; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Weight Loss | 1996 |
Prophylactic effect of serotonin uptake inhibitors against motion sickness in Suncus murinus.
Topics: Animals; Dose-Response Relationship, Drug; Fluoxetine; Imipramine; Male; Motion Sickness; Selective Serotonin Reuptake Inhibitors | 1996 |
Study addresses question of preferred initial therapy for depression.
Topics: Antidepressive Agents, Tricyclic; Cost-Benefit Analysis; Depression; Desipramine; Drug Costs; Fluoxetine; Humans; Imipramine; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors | 1996 |
SSRI or tricyclics for depression?
Topics: Adult; Depression; Depressive Disorder; Desipramine; Family Practice; Fluoxetine; Humans; Imipramine; Randomized Controlled Trials as Topic; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 1996 |
Interactions of selective serotonin reuptake inhibitors with the serotonin 5-HT2c receptor.
Topics: Animals; Antidepressive Agents, Tricyclic; Choroid Plexus; Citalopram; Fluoxetine; Imipramine; Male; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors | 1996 |
Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography.
Topics: 20-alpha-Dihydroprogesterone; Adrenalectomy; Animals; Brain; Castration; Fluoxetine; GABA Modulators; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Imipramine; Male; Paroxetine; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley | 1996 |
Alterations in plasma dipeptidyl peptidase IV enzyme activity in depression and schizophrenia: effects of antidepressants and antipsychotic drugs.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Dipeptidyl Peptidase 4; Dose-Response Relationship, Drug; Female; Fluoxetine; Haloperidol; Humans; Hydrocortisone; Imipramine; Male; Middle Aged; Nortriptyline; Perphenazine; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology | 1996 |
Changes in serotonin and norepinephrine uptake sites after chronic cocaine: pre- vs. post-withdrawal effects.
Topics: Administration, Oral; Animals; Autoradiography; Biological Transport; Brain; Carrier Proteins; Cocaine; Drug Administration Schedule; Female; Fluoxetine; Imipramine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Organ Specificity; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Substance Withdrawal Syndrome; Substance-Related Disorders; Symporters; Time Factors; Tritium | 1996 |
Identification of hypothalamic transcripts upregulated by antidepressants.
Topics: Animals; Antidepressive Agents, Tricyclic; Fluoxetine; Gene Expression Regulation; Hypothalamus; Imipramine; Male; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Transcription, Genetic | 1996 |
Contribution of lysosomal trapping to the total tissue uptake of psychotropic drugs.
Topics: 1-Naphthylamine; Amitriptyline; Ammonium Chloride; Animals; Antidepressive Agents, Tricyclic; Carbamazepine; Drug Interactions; Fluoxetine; Imipramine; Lysosomes; Male; Monensin; Phospholipids; Promazine; Psychotropic Drugs; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Sertraline; Tissue Distribution | 1997 |
Cost-effectiveness of newer antidepressants compared with tricyclic antidepressants in managed care settings.
Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Cost Savings; Cost-Benefit Analysis; Decision Support Techniques; Depressive Disorder; Drug Costs; Fluoxetine; Health Care Costs; Health Policy; Health Services; Humans; Imipramine; Managed Care Programs; Patient Compliance; Piperazines; Probability; Quality-Adjusted Life Years; Treatment Failure; Treatment Outcome; Triazoles | 1997 |
Influence of antidepressant drugs on learning and memory paradigms in mice.
Topics: Aged; Amitriptyline; Animals; Antidepressive Agents; Depression; Female; Fluoxetine; Humans; Imipramine; Learning; Male; Memory; Mice; Muscarinic Antagonists; Scopolamine | 1996 |
Partial role of 5-HT2 and 5-HT3 receptors in the activity of antidepressants in the mouse forced swimming test.
Topics: Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Desipramine; Drug Interactions; Fluoxetine; Fluvoxamine; Imipramine; Ketanserin; Male; Maprotiline; Mice; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming | 1997 |
[A study of the effects of antidepressants on the GABAA receptor and its complex based on the drug actions on the power-spectral changes of rat hippocampal EEG induced by GABA antagonists and inverse agonists].
Topics: Animals; Antidepressive Agents; Carbolines; Depression, Chemical; Desipramine; Electroencephalography; Fluoxetine; GABA Antagonists; Hippocampus; Imipramine; Male; Norepinephrine; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, GABA-A; Serotonin; Trazodone | 1997 |
Venlafaxine: in vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs, and effects on human hepatic CYP3A4, CYP2C9 and CYP1A2.
Topics: 1-Naphthylamine; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cyclohexanols; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desipramine; Fluoxetine; Fluvoxamine; Frozen Sections; Humans; Hydroxylation; Imipramine; In Vitro Techniques; Lethal Dose 50; Microsomes, Liver; Mixed Function Oxygenases; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Venlafaxine Hydrochloride | 1997 |
Sensitive and rapid method for the simultaneous quantification of five antidepressants with their respective metabolites in plasma using high-performance liquid chromatography with diode-array detection.
Topics: Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Fluoxetine; Humans; Imipramine; Maprotiline; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 1997 |
The serotonin transporter messenger RNA level in rat brain is not regulated by antidepressants.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Blotting, Northern; Brain Chemistry; Carrier Proteins; Fluoxetine; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Rats, Wistar; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Thiazepines | 1997 |
Interactions between promazine and antidepressants at the level of cellular distribution.
Topics: 1-Naphthylamine; Amitriptyline; Ammonium Chloride; Animals; Antidepressive Agents; Antipsychotic Agents; Carbamazepine; Drug Interactions; Fluoxetine; Hydrogen-Ion Concentration; Imipramine; Lysosomes; Male; Promazine; Rats; Rats, Wistar; Sertraline | 1997 |
Pinch-induced catalepsy in mice: a useful model to investigate antidepressant or anxiolytic drugs.
Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Antidepressive Agents; Catalepsy; Female; Fluoxetine; Fluvoxamine; Imipramine; Learning; Male; Mice; Models, Psychological; Motor Activity; Ondansetron; Physical Stimulation; Reaction Time; Serotonin Antagonists; Sex Characteristics; Stereotyped Behavior | 1998 |
Differential effects of chronic antidepressant treatment on swim stress- and fluoxetine-induced secretion of corticosterone and progesterone.
Topics: Animals; Antidepressive Agents; Corticosterone; Fluoxetine; Imipramine; Male; Phenelzine; Progesterone; Rats; Rats, Sprague-Dawley; Stress, Physiological; Swimming | 1998 |
Selective serotonin reuptake inhibitors potentiate 8-OH-DPAT-induced stimulus control in the pigeon.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Citalopram; Columbidae; Conditioning, Operant; Discrimination, Psychological; Drug Synergism; Fluoxetine; Generalization, Stimulus; Imipramine; Male; Neurotransmitter Uptake Inhibitors; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists | 1998 |
Kinetic interaction between fluoxetine and imipramine as a function of elevated serum alpha-1-acid glycoprotein levels.
Topics: Animals; Antidepressive Agents, Tricyclic; Drug Interactions; Fluoxetine; Glycoproteins; Imipramine; Mice; Mice, Inbred C57BL; Selective Serotonin Reuptake Inhibitors | 1998 |
Affinities of venlafaxine and various reuptake inhibitors for the serotonin and norepinephrine transporters.
Topics: Animals; Antidepressive Agents, Second-Generation; Binding, Competitive; Brain; Carrier Proteins; Cyclohexanols; Fluoxetine; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Radioligand Assay; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Symporters; Venlafaxine Hydrochloride | 1998 |
Differential effects of chronic imipramine and fluoxetine on basal and amphetamine-induced extracellular dopamine levels in rat nucleus accumbens.
Topics: Amphetamine; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Area Under Curve; Dopamine; Dopamine Uptake Inhibitors; Extracellular Space; Fluoxetine; Imipramine; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1998 |
In vivo evaluation of serotonergic agents and alpha-adrenergic blockers on premature ejaculation by inhibiting the seminal vesicle pressure response to electrical nerve stimulation.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Clomipramine; Dose-Response Relationship, Drug; Ejaculation; Electric Stimulation; Fluoxetine; Imipramine; Male; Prazosin; Pressure; Rats; Rats, Wistar; Seminal Vesicles; Serotonin; Serotonin Agents; Sexual Dysfunction, Physiological; Splanchnic Nerves; Sympatholytics | 1998 |
Guinea pig 5-HT transporter: cloning, expression, distribution, and function in intestinal sensory reception.
Topics: Amino Acid Sequence; Animals; Base Sequence; Biological Transport; Brain Stem; Carrier Proteins; Clomipramine; Cloning, Molecular; Desipramine; DNA, Complementary; Fluoxetine; Guinea Pigs; HeLa Cells; Humans; Imipramine; Intestinal Mucosa; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Nerve Tissue Proteins; Neurons; Peristalsis; Polymerase Chain Reaction; Rats; Recombinant Proteins; RNA, Messenger; Serotonin; Serotonin Plasma Membrane Transport Proteins; Transcription, Genetic; Zimeldine | 1998 |
Estimation of apoptosis in C6 glioma cells treated with antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Apoptosis; DNA Fragmentation; Fluoxetine; Glioma; Humans; Imipramine; Tumor Cells, Cultured | 1997 |
Effect of antidepressants on intracellular Ca++ mobilization in human frontal cortex.
Topics: Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Calcium; Calcium Channel Blockers; Female; Fluoxetine; Humans; Imipramine; In Vitro Techniques; Male; Middle Aged; Prefrontal Cortex; Protein Synthesis Inhibitors; Selective Serotonin Reuptake Inhibitors; Synaptosomes | 1998 |
Modelling the cost effectiveness of antidepressant treatment in primary care.
Topics: Antidepressive Agents; Decision Support Techniques; Depressive Disorder; Female; Fluoxetine; Humans; Imipramine; Markov Chains; Models, Economic; Piperazines; Primary Health Care; Quality-Adjusted Life Years; Sensitivity and Specificity; Triazoles | 1995 |
Milnacipran: new preparation. Tricyclics remain first-line antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Clomipramine; Cyclopropanes; Drug Evaluation; Europe; Fluoxetine; Fluvoxamine; Humans; Imipramine; Meta-Analysis as Topic; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; United States | 1998 |
Pharmacological profile of neuroleptics at human monoamine transporters.
Topics: Antipsychotic Agents; Carrier Proteins; Cell Line; Chlorpromazine; Cocaine; Dibenzazepines; Dibenzothiepins; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Humans; Imipramine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Pimozide; Piperazines; Protein Binding; Radioligand Assay; Recombinant Fusion Proteins; Serotonin Plasma Membrane Transport Proteins; Symporters; Thiazoles; Triflupromazine; Tritium | 1999 |
Venlafaxine: new preparation. Just another antidepressant.
Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cyclohexanols; Depressive Disorder, Major; Double-Blind Method; Drug Evaluation; Fluoxetine; Humans; Imipramine; Meta-Analysis as Topic | 1998 |
The role of lysosomes in the cellular distribution of thioridazine and potential drug interactions.
Topics: Amitriptyline; Ammonium Chloride; Animals; Antidepressive Agents; Chromatography, High Pressure Liquid; Drug Interactions; Fluoxetine; Imipramine; In Vitro Techniques; Lysosomes; Male; Monensin; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Sertraline; Thioridazine | 1999 |
Molecular cloning, expression and characterization of a bovine serotonin transporter.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cattle; Citalopram; Cloning, Molecular; Desipramine; Female; Fluoxetine; HeLa Cells; Humans; Imipramine; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Organ Specificity; Paroxetine; Phylogeny; Pregnancy; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin; Serotonin Plasma Membrane Transport Proteins; Transfection | 1999 |
Efficacy of an Hypericum perforatum (St. John's wort) extract in preventing and reverting a condition of escape deficit in rats.
Topics: Acute Disease; Animals; Appetite; Benzazepines; Chronic Disease; Disease Models, Animal; Electroshock; Ericales; Escape Reaction; Fluoxetine; Imipramine; Male; Motor Activity; Pain; Plant Extracts; Rats; Rats, Sprague-Dawley; Stress, Psychological | 1999 |
Comparison of hypericum extracts with imipramine and fluoxetine in animal models of depression and alcoholism.
Topics: Alcoholism; Animals; Antidepressive Agents; Depression; Drug Evaluation, Preclinical; Female; Fluoxetine; Hypericum; Imipramine; Male; Phytotherapy; Plants, Medicinal; Rats; Rats, Wistar | 1999 |
Effect of fluoxetine on contractile activity of pregnant rat uterine rings.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Tricyclic; Dose-Response Relationship, Drug; Female; Fluoxetine; Imipramine; Isometric Contraction; Nortriptyline; Pregnancy; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Uterine Contraction; Uterus | 2000 |
Pharmacological blockade or genetic deletion of substance P (NK(1)) receptors attenuates neonatal vocalisation in guinea-pigs and mice.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Buspirone; Diazepam; Dose-Response Relationship, Drug; Female; Fluoxetine; Gene Deletion; Guinea Pigs; Imipramine; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Motor Activity; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Social Isolation; Stress, Psychological; Substance P; Tetrazoles; Vocalization, Animal | 2000 |
Effects of the combination of halothane and serotonin uptake blockers on synaptic transmission in the rat dentate gyrus in vitro.
Topics: Anesthetics, Inhalation; Animals; Antidepressive Agents, Tricyclic; Dentate Gyrus; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Postsynaptic Potentials; Fluoxetine; Halothane; Imipramine; In Vitro Techniques; Male; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Synaptic Transmission | 2000 |
Acute treatments with GMP produce antidepressant-like effects in mice.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Dizocilpine Maleate; Drug Synergism; Excitatory Amino Acid Antagonists; Fenclonine; Fluoxetine; Guanosine Monophosphate; Hindlimb Suspension; Imipramine; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Motor Activity; Serotonin Antagonists; Swimming; Time Factors | 2000 |
Selective increase of dopamine D3 receptor gene expression as a common effect of chronic antidepressant treatments.
Topics: Amitriptyline; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Desipramine; Dopamine; Dynorphins; Electroshock; Fluoxetine; Gene Expression; Imipramine; Islands of Calleja; Limbic System; Male; Monoamine Oxidase Inhibitors; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Substance P; Tranylcypromine | 2000 |
TCAs or SSRIs as initial therapy for depression?
Topics: Adult; Antidepressive Agents, Tricyclic; Costs and Cost Analysis; Depression; Depressive Disorder; Desipramine; Female; Fluoxetine; Humans; Imipramine; Male; Randomized Controlled Trials as Topic; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 1999 |
Strain-dependent neurochemical and neuroendocrine effects of desipramine, but not fluoxetine or imipramine, in spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Brain Chemistry; Desipramine; Fluoxetine; Imipramine; Male; Mesencephalon; Neurosecretory Systems; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, beta; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Species Specificity | 2000 |
Electrophysiologic analysis of antidepressant drug effects on the GABA(A) receptor complex based upon antagonist-induced encephalographic power spectrum changes.
Topics: Animals; Antidepressive Agents; Desipramine; Electroencephalography; Fluoxetine; Fourier Analysis; GABA Antagonists; Hippocampus; Imipramine; Male; Nortriptyline; Pentylenetetrazole; Rats; Rats, Wistar; Trazodone | 2000 |
Treatment of depression with associated anxiety: comparisons of tricyclic antidepressants and selective serotonin reuptake inhibitors.
Topics: Antidepressive Agents, Tricyclic; Anxiety Disorders; Clomipramine; Depressive Disorder, Major; Fluoxetine; Humans; Imipramine; Selective Serotonin Reuptake Inhibitors | 2000 |
Antidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitro.
Topics: Animals; Antidepressive Agents; Brain; Cell Division; Cells, Cultured; Cerebellum; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Imipramine; Nervous System; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Thymidine | 2001 |
Plasticity in serotonin uptake in primary neuronal cultures of serotonin transporter knockout mice.
Topics: Adrenergic Uptake Inhibitors; Animals; Biological Transport; Carrier Proteins; Cells, Cultured; Dopamine Uptake Inhibitors; Fluoxetine; Imipramine; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Nomifensine; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tritium | 2001 |
Anti-Inflammatory effects of antidepressants through suppression of the interferon-gamma/interleukin-10 production ratio.
Topics: 5-Hydroxytryptophan; Adult; Analysis of Variance; Antidepressive Agents; Cyclohexanols; Depressive Disorder; Female; Fluoxetine; Humans; Imipramine; Interferon-gamma; Interleukin-10; Male; Middle Aged; Venlafaxine Hydrochloride | 2001 |
Animal models for the study of antidepressant activity.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Appetite; Behavior, Animal; Depression; Disease Models, Animal; Drug Evaluation, Preclinical; Escape Reaction; Fluoxetine; Imipramine; Male; Maze Learning; Phenelzine; Rats; Rats, Sprague-Dawley; Reward; Stress, Physiological; Time Factors | 2001 |
Effects of antidepressant drugs on the behavioral and physiological responses to lipopolysaccharide (LPS) in rodents.
Topics: Adrenal Glands; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Behavior, Animal; Body Temperature; Brain; Corticosterone; Cytokines; Drug Administration Schedule; Drug Interactions; Fluoxetine; Hypothalamo-Hypophyseal System; Imipramine; Immune System; Lipopolysaccharides; Male; Neuroimmunomodulation; Rats; Rats, Inbred F344; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Spleen | 2001 |
Lack of interaction between flibanserin and antidepressants in inducing serotonergic syndrome in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Benzimidazoles; Drug Interactions; Fluoxetine; Imipramine; Male; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Serotonin Syndrome | 2001 |
The alpha(2a)-adrenergic receptor plays a protective role in mouse behavioral models of depression and anxiety.
Topics: Adrenergic Uptake Inhibitors; Animals; Anxiety; Behavior, Animal; Darkness; Depression; Disease Models, Animal; Female; Fluoxetine; Imipramine; Light; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Adrenergic, alpha-2; Selective Serotonin Reuptake Inhibitors; Spatial Behavior; Stress, Physiological; Swimming | 2001 |
Mood disorders in children and adolescents: psychopharmacological treatment.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Child; Depressive Disorder, Major; Drug Therapy, Combination; Fluoxetine; Health Services Needs and Demand; Humans; Imipramine; Mood Disorders; Paroxetine; Selective Serotonin Reuptake Inhibitors | 2001 |
A study of the antidepressant activity of Hypericum perforatum on animal models.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bridged Bicyclo Compounds; Chronic Disease; Depression; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Electroshock; Fluoxetine; Hypericum; Imipramine; Microdialysis; Phloroglucinol; Plant Extracts; Rats; Stress, Physiological; Terpenes | 2001 |
Antagonism of nicotinic acetylcholine receptors by inhibitors of monoamine uptake.
Topics: Acetylcholine; Animals; Antidepressive Agents; Biogenic Monoamines; Female; Fluoxetine; Imipramine; Membrane Potentials; Muscle, Skeletal; Neurons; Neurotransmitter Uptake Inhibitors; Oocytes; Protein Subunits; Rats; Receptors, Nicotinic; Recombinant Proteins; Xenopus laevis; Zimeldine | 2001 |
In vivo and in vitro effect of imipramine and fluoxetine on Na+,K+-ATPase activity in synaptic plasma membranes from the cerebral cortex of rats.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cerebral Cortex; Fluoxetine; Imipramine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Sodium-Potassium-Exchanging ATPase; Synaptic Membranes | 2001 |
Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antidiuretic Hormone Receptor Antagonists; Anxiety; Behavior, Animal; Depression; Feeding Behavior; Fluoxetine; Imipramine; Indoles; Kinetics; Male; Mice; Mice, Inbred BALB C; Pyrrolidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Risk Assessment; Stress, Physiological; Stress, Psychological; Time Factors | 2002 |
Neurochemical and behavioural characterization of milnacipran, a serotonin and noradrenaline reuptake inhibitor in rats.
Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Behavior, Animal; Binding, Competitive; Brain Chemistry; Conditioning, Psychological; Cyclopropanes; Dose-Response Relationship, Drug; Fear; Fluoxetine; Fluvoxamine; Imipramine; Male; Maprotiline; Microdialysis; Milnacipran; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Prefrontal Cortex; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Cell Surface; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Swimming; Synaptosomes; Time Factors | 2002 |
Repeated treatment with antidepressants differentially alters 5-HT1A agonist-stimulated [35S]GTP gamma S binding in rat brain regions.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Brain; Clorgyline; Dose-Response Relationship, Drug; Drug Administration Schedule; Fluoxetine; Guanosine 5'-O-(3-Thiotriphosphate); Imipramine; Male; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Sulfur Radioisotopes | 2002 |
A typological model for estimation of drug and placebo effects in depression.
Topics: Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder, Major; Fluoxetine; Humans; Imipramine; Models, Psychological; Placebos | 2002 |
Adaptation of monoaminergic responses to phencyclidine in nucleus accumbens and prefrontal cortex following repeated treatment with fluoxetine or imipramine.
Topics: Adaptation, Physiological; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Biogenic Monoamines; Depressive Disorder; Dopamine; Excitatory Amino Acid Antagonists; Fluoxetine; Imipramine; Male; Neostriatum; Nucleus Accumbens; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Selective Serotonin Reuptake Inhibitors; Serotonin | 2002 |
Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Cyclic AMP Response Element-Binding Protein; Female; Fluoxetine; Imipramine; Kinetics; Male; Mice; Mice, Transgenic; Neurons; Neurotrophin 3; Phosphorylation; Prefrontal Cortex; Receptor, trkB; Signal Transduction | 2003 |
Impact of nonspecific binding to microsomes and phospholipid on the inhibition of cytochrome P4502D6: implications for relating in vitro inhibition data to in vivo drug interactions.
Topics: Benzylamines; Bridged Bicyclo Compounds, Heterocyclic; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Enzyme Inhibitors; Ethanolamines; Fluoxetine; Humans; Imipramine; In Vitro Techniques; Microsomes; Phospholipids; Protein Binding; Quinidine | 2003 |
Evaluation of the anti-inflammatory and anti-nociceptive effects of different antidepressants in the rat.
Topics: Amitriptyline; Analysis of Variance; Animals; Antidepressive Agents; Carrageenan; Clomipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Fluoxetine; Imipramine; Inflammation; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Sertraline; Trazodone | 2003 |
Pharmacological and autoradiographical characterization of serotonin transporter-like activity in sporocysts of the human blood fluke, Schistosoma mansoni.
Topics: Animals; Autoradiography; Biological Transport, Active; Chlorine; Dose-Response Relationship, Drug; Fluoxetine; Gene Expression Regulation, Enzymologic; Host-Parasite Interactions; Imipramine; Oocysts; Schistosoma mansoni; Serotonin; Snails; Sodium | 2003 |
Functional coupling of serotonin and noradrenaline transporters.
Topics: Amino Acid Sequence; Animals; Antidepressive Agents; Binding, Competitive; Carrier Proteins; Cell Line; Cell Membrane; Citalopram; Fluoxetine; Humans; Imipramine; Immunoblotting; Kidney; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Recombinant Fusion Proteins; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters; Transfection; Tritium | 2003 |
Involvement of NMDA receptors and L-arginine-nitric oxide pathway in the antidepressant-like effects of zinc in mice.
Topics: Animals; Antidepressive Agents; Arginine; Ascorbic Acid; Behavior, Animal; Chlorides; Depression; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Fluoxetine; Free Radical Scavengers; Guanosine Monophosphate; Hindlimb Suspension; Imipramine; Immobilization; Ketamine; Male; Mice; Motor Activity; Nitric Oxide; Nitric Oxide Donors; Pain Measurement; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; Swimming; Time Factors; Zinc Compounds | 2003 |
Evidence that the metabotropic glutamate receptor 5 antagonist MPEP may act as an inhibitor of the norepinephrine transporter in vitro and in vivo.
Topics: Action Potentials; Adrenergic Uptake Inhibitors; Amygdala; Animals; Antidepressive Agents, Tricyclic; Binding, Competitive; Desipramine; Electrochemistry; Excitatory Amino Acid Antagonists; Fluoxetine; Humans; Imipramine; In Vitro Techniques; Locus Coeruleus; Male; Microelectrodes; Norepinephrine Plasma Membrane Transport Proteins; Pyridines; Radioligand Assay; Rats; Receptors, Kainic Acid; Symporters; Time Factors | 2003 |
Studies on the anti-inflammatory effect of fluoxetine in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Carrageenan; Celecoxib; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Edema; Fluoxetine; Foot; Imipramine; Indomethacin; Inflammation; Lactones; Melatonin; Pyrazoles; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Sulfonamides; Sulfones; Time Factors; Trazodone | 2004 |
Extracts of St. John's wort and various constituents affect beta-adrenergic binding in rat frontal cortex.
Topics: Animals; Anthracenes; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bridged Bicyclo Compounds; Cell Membrane; Fluoxetine; Frontal Lobe; Hypericum; Imipramine; Male; Perylene; Phloroglucinol; Plant Extracts; Quercetin; Radioligand Assay; Rats; Receptors, Adrenergic, beta; Terpenes | 2004 |
Antidepressant activity of quercetin, a bioflavonoid, in streptozotocin-induced diabetic mice.
Topics: Animals; Antidepressive Agents; Depression; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoxetine; Imipramine; Injections, Intraperitoneal; Male; Quercetin; Random Allocation; Rats; Treatment Outcome | 2003 |
Stimulatory effect of antidepressants on the production of IL-6.
Topics: 5-Hydroxytryptophan; Adult; Age Factors; Aging; Antidepressive Agents; Blood Cells; Cyclohexanols; Depressive Disorder; Drug Combinations; Female; Fluoxetine; Humans; Imipramine; In Vitro Techniques; Inflammation; Interleukin-6; Male; Middle Aged; Tumor Necrosis Factor-alpha; Venlafaxine Hydrochloride | 2004 |
Are selective serotonin re-uptake inhibitors associated with an increased risk of self-harm by antidepressant overdose?
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Citalopram; Cyclohexanols; Doxepin; Drug Overdose; Drug Prescriptions; Emergency Service, Hospital; Female; Fluoxetine; Humans; Imipramine; Information Services; Male; Mianserin; Mirtazapine; Paroxetine; Patient Admission; Patient Readmission; Poison Control Centers; Retrospective Studies; Risk Assessment; Scotland; Selective Serotonin Reuptake Inhibitors; Self-Injurious Behavior; Sertraline; Trazodone; Venlafaxine Hydrochloride | 2004 |
Nitric oxide synthase inhibitors augment the effects of serotonin re-uptake inhibitors in the forced swimming test.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Dose-Response Relationship, Drug; Drug Synergism; Escape Reaction; Fluoxetine; Imipramine; Immobilization; Indazoles; Male; Mice; Motor Activity; Nitric Oxide Synthase; Nitroarginine; Selective Serotonin Reuptake Inhibitors; Swimming | 2004 |
Effects of myo-inositol versus fluoxetine and imipramine pretreatments on serotonin 5HT2A and muscarinic acetylcholine receptors in human neuroblastoma cells.
Topics: Adrenergic Uptake Inhibitors; Androstadienes; Atropine; Cell Line, Tumor; Enzyme Inhibitors; Estrenes; Fluoxetine; Humans; Imipramine; Inositol; Muscarinic Antagonists; Neuroblastoma; Phosphatidylinositols; Phosphodiesterase Inhibitors; Pyrrolidinones; Receptor, Serotonin, 5-HT2A; Receptors, Muscarinic; Selective Serotonin Reuptake Inhibitors; Tritium; Wortmannin | 2004 |
Pharmacological and neurochemical evidence for antidepressant-like effects of the herbal product Catuama.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Dopamine; Dose-Response Relationship, Drug; Fluoxetine; Imipramine; In Vitro Techniques; Mice; Neurotransmitter Agents; Plant Extracts; Rats; Rats, Wistar; Serotonin; Swimming; Synaptosomes | 2004 |
Hydroxyzine prevents isolation-induced vocalization in guinea pig pups: comparison with chlorpheniramine and immepip.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Chlordiazepoxide; Chlorpheniramine; Dose-Response Relationship, Drug; Fluoxetine; Guinea Pigs; Histamine Agonists; Histamine H1 Antagonists; Hydroxyzine; Hypnotics and Sedatives; Imidazoles; Imipramine; Piperidines; Social Isolation; Vocalization, Animal | 2004 |
Opposite effects of antidepressants on unstimulated and stimulated salivary flow.
Topics: Amylases; Animals; Antidepressive Agents; Calcium; Fluoxetine; Imipramine; Male; Moclobemide; Muscarinic Agonists; Phosphates; Pilocarpine; Rats; Rats, Wistar; Saliva; Salivary Proteins and Peptides; Salivation; Xerostomia | 2005 |
Selective serotonin reuptake inhibitors induce spontaneous interneuronal activity in the leech nervous system.
Topics: Action Potentials; Adrenergic Uptake Inhibitors; Animals; Citalopram; Drug Interactions; Electric Stimulation; Fluoxetine; Ganglia, Invertebrate; Imipramine; In Vitro Techniques; Interneurons; Leeches; Membrane Potentials; Neural Networks, Computer; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin; Synapses | 2005 |
Serotonin (5HT), fluoxetine, imipramine and dopamine target distinct 5HT receptor signaling to modulate Caenorhabditis elegans egg-laying behavior.
Topics: Animals; Behavior, Animal; Caenorhabditis elegans; Dopamine; Female; Fluoxetine; Gene Deletion; Helminth Proteins; Imipramine; Oviposition; Receptors, Serotonin; Serotonin | 2005 |
Modafinil enhances the increase of extracellular serotonin levels induced by the antidepressant drugs fluoxetine and imipramine: a dual probe microdialysis study in awake rat.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzhydryl Compounds; Brain; Central Nervous System Stimulants; Depressive Disorder; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Extracellular Fluid; Fluoxetine; Imipramine; Male; Microdialysis; Modafinil; Neural Pathways; Prefrontal Cortex; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Up-Regulation; Wakefulness | 2005 |
QTc prolongation associated with combination therapy of levofloxacin, imipramine, and fluoxetine.
Topics: Anti-Infective Agents, Urinary; Antidepressive Agents; Cytochrome P-450 CYP2D6 Inhibitors; Drug Synergism; Female; Fluoxetine; Humans; Imipramine; Levofloxacin; Long QT Syndrome; Middle Aged; Ofloxacin | 2005 |
Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus.
Topics: Animals; Antidepressive Agents; Apoptosis; Brain-Derived Neurotrophic Factor; Cell Division; Dentate Gyrus; Female; Fluoxetine; Heterozygote; Imipramine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Knockout; Mice, Transgenic; Neurons; Receptor, trkB; Signal Transduction | 2005 |
Chronic fluoxetine administration inhibits extracellular signal-regulated kinase 1/2 phosphorylation in rat brain.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Cell Nucleus; Cytoplasm; Fluoxetine; Frontal Lobe; Hippocampus; Imipramine; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors | 2005 |
Antidepressant-like effect of hyperbaric oxygen treatment in forced-swimming test in rats.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depression; Fluoxetine; Hyperbaric Oxygenation; Imipramine; Male; Rats; Rats, Wistar; Swimming | 2005 |
Early treatment of acute stress disorder in children with major burn injury.
Topics: Adolescent; Adult; Antidepressive Agents; Burns; Child; Child, Preschool; Female; Fluoxetine; Humans; Imipramine; Infant; Male; Retrospective Studies; Stress Disorders, Traumatic, Acute | 2005 |
Reduction of Submissive Behavior Model for antidepressant drug activity testing: study using a video-tracking system.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Competitive Behavior; Dominance-Subordination; Feeding Behavior; Fluoxetine; Imipramine; Maprotiline; Mice; Naltrexone; Narcotic Antagonists; Rats | 2005 |
Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress.
Topics: Aggression; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depression; Dominance-Subordination; Dopamine; Fluoxetine; Gene Expression Profiling; Gene Expression Regulation; Imipramine; Limbic System; Male; Mice; Mice, Inbred C57BL; Neurons; Nucleus Accumbens; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-fos; Social Behavior; Social Isolation; Stress, Psychological; Ventral Tegmental Area | 2006 |
Impairment of the spatial learning and memory induced by learned helplessness and chronic mild stress.
Topics: Animals; Base Sequence; Brain-Derived Neurotrophic Factor; Chronic Disease; Corticosterone; Cyclic AMP Response Element-Binding Protein; DNA Primers; Fluoxetine; Imipramine; Learning; Male; Memory; Mice; Mice, Inbred ICR; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stress, Physiological | 2006 |
Antidepressant-like activity of n-hexane extract of nutmeg (Myristica fragrans) seeds in mice.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Dopamine Antagonists; Drug Interactions; Fenclonine; Fluoxetine; Hexanes; Imipramine; Male; Mice; Motor Activity; Myristica; Plant Extracts; Prazosin; Seeds; Serotonin Antagonists; Sulpiride; Swimming | 2006 |
Induction of neuroserpin expression in rat frontal cortex after chronic antidepressant treatment and electroconvulsive treatment.
Topics: Animals; Antidepressive Agents; Cyclohexanols; Electroconvulsive Therapy; Expressed Sequence Tags; Fluoxetine; Frontal Lobe; Imipramine; Male; Neuropeptides; Neuroserpin; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serpins; Sertraline; Venlafaxine Hydrochloride | 2006 |
(-)-Trans-epsilon-viniferin, a polyphenol present in wines, is an inhibitor of noradrenaline and 5-hydroxytryptamine uptake and of monoamine oxidase activity.
Topics: Animals; Benzofurans; Blood Platelets; Brain; Cell Line; Citalopram; Clorgyline; Dose-Response Relationship, Drug; Fluoxetine; Humans; Imipramine; Iproniazid; Isoenzymes; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Selegiline; Serotonin; Stilbenes; Synaptosomes; Tritium; Wine | 2006 |
Narcolepsy in Saudi Arabia. Demographic and clinical perspective of an under-recognized disorder.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Aged; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Child; Clomipramine; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Narcolepsy; Polysomnography; Saudi Arabia | 2006 |
Early treatment of acute stress symptoms in pediatric burn patients with imipramine and fluoxetine.
Topics: Antidepressive Agents; Burns; Child; Clinical Protocols; Fluoxetine; Humans; Imipramine; Pediatrics; Stress Disorders, Traumatic, Acute | 2006 |
Stimulation of the beta3-Adrenoceptor as a novel treatment strategy for anxiety and depressive disorders.
Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Aggression; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Anxiety Disorders; Behavior, Animal; Cognition; Depressive Disorder; Diazepam; Ethanol; Exploratory Behavior; Fluoxetine; Gerbillinae; Imipramine; Interpersonal Relations; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Adrenergic, beta-3; Sleep; Substance-Related Disorders; Swimming; Tetrahydronaphthalenes | 2008 |
Comparative metabolic capabilities and inhibitory profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17.
Topics: Atomoxetine Hydrochloride; Cocaine; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Debrisoquin; Dextromethorphan; Enzyme Inhibitors; Ethanolamines; Fluoxetine; Humans; Hydroxylation; Imipramine; Kinetics; Microsomes; Molecular Structure; Nortriptyline; Polymorphism, Single Nucleotide; Propylamines; Quinidine; Recombinant Proteins; Thioridazine; Tramadol | 2007 |
Saturable uptake of lipophilic amine drugs into isolated hepatocytes: mechanisms and consequences for quantitative clearance prediction.
Topics: Algorithms; Amines; Animals; Biological Transport; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Dextromethorphan; Fluoxetine; Fluvoxamine; Hepatocytes; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Imipramine; In Vitro Techniques; Kinetics; Male; Models, Biological; Propranolol; Quinine; Rats; Rats, Sprague-Dawley | 2007 |
High-speed imaging reveals neurophysiological links to behavior in an animal model of depression.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Dentate Gyrus; Depressive Disorder; Diagnostic Imaging; Disease Models, Animal; Electric Stimulation; Electrophysiology; Female; Fluoxetine; Hippocampus; Imipramine; Motor Activity; Nerve Net; Neurons; Rats; Rats, Inbred F344; Selective Serotonin Reuptake Inhibitors; Stress, Physiological | 2007 |
Antidepressant drugs reverse the loss of adult neural stem cells following chronic stress.
Topics: Animals; Antidepressive Agents; Biological Assay; Cell Death; Cells, Cultured; Chronic Disease; Corticosterone; Disease Models, Animal; Fluoxetine; Glucocorticoids; Imipramine; Lateral Ventricles; Male; Mice; Mice, Inbred ICR; Nerve Degeneration; Olfactory Bulb; Selective Serotonin Reuptake Inhibitors; Serotonin; Spheroids, Cellular; Stem Cells; Stress, Psychological; Swimming; Telencephalon | 2007 |
Temporal expression of brain-derived neurotrophic factor (BDNF) mRNA in the rat hippocampus after treatment with selective and mixed monoaminergic antidepressants.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cyclohexanols; Dentate Gyrus; Fluoxetine; GAP-43 Protein; Hippocampus; Imipramine; Male; Neuronal Plasticity; Neurotransmitter Uptake Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Synaptophysin; Time Factors; Transcription, Genetic; Venlafaxine Hydrochloride | 2008 |
Juvenile rats in the forced-swim test model the human response to antidepressant treatment for pediatric depression.
Topics: Adolescent; Age Factors; Animals; Antidepressive Agents; Child; Citalopram; Depressive Disorder; Desipramine; Disease Models, Animal; Escape Reaction; Fluoxetine; Helplessness, Learned; Humans; Imipramine; Injections, Intraperitoneal; Male; Motivation; Rats; Rats, Sprague-Dawley; Swimming; Tranylcypromine | 2008 |
Fluoxetine (prozac) in depresion of adults.
Topics: Adolescent; Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depressive Disorder; Electroencephalography; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Psychiatric Status Rating Scales | 1991 |
Chronic low dose corticosterone exposure decreased hippocampal cell proliferation, volume and induced anxiety and depression like behaviours in mice.
Topics: Adrenal Glands; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antimetabolites; Anxiety; Behavior, Animal; Bromodeoxyuridine; Cell Proliferation; Chemistry, Pharmaceutical; Corticosterone; Depression; Fluoxetine; Hippocampus; Imipramine; Immunohistochemistry; Lighting; Male; Mice; Organ Size; Swimming | 2008 |
Antidepressant effect of Yueju-Wan ethanol extract and its fractions in mice models of despair.
Topics: 1-Butanol; Acetates; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Depression; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Ethanol; Ethers; Fluoxetine; Hindlimb Suspension; Imipramine; Male; Mice; Mice, Inbred ICR; Motor Activity; Solvents; Swimming; Water | 2008 |
Modelling the anxiety-depression continuum in chicks.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Chickens; Chlordiazepoxide; Clonidine; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoxetine; Imipramine; Interleukin-6; Maprotiline; Social Isolation; Stress, Psychological | 2009 |
Mouse strain differences in the unpredictable chronic mild stress: a four-antidepressant survey.
Topics: Animals; Animals, Outbred Strains; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; Chronic Disease; Depression; Desipramine; Fluoxetine; Grooming; Imipramine; Injections, Intraperitoneal; Male; Maprotiline; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Selective Serotonin Reuptake Inhibitors; Species Specificity; Stress, Psychological; Time Factors | 2008 |
Vasoactive properties of antidepressant N-alkyl derivatives.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Aorta, Thoracic; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Fluoxetine; Imipramine; Male; Methylation; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship | 2007 |
The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling.
Topics: Affect; Analysis of Variance; Animals; Antidepressive Agents; Antidiuretic Hormone Receptor Antagonists; Behavior, Animal; Cytostatic Agents; Depression; Drug Combinations; Fluoxetine; Hippocampus; Imipramine; Indoles; Male; Methylazoxymethanol Acetate; Mitosis; Neurogenesis; Neuronal Plasticity; Prefrontal Cortex; Pyrrolidines; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological | 2009 |
Differential sensitivity to SSRI and tricyclic antidepressants in juvenile and adult mice of three strains.
Topics: Aging; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Fluoxetine; Hindlimb Suspension; Imipramine; Male; Mice; Mice, Inbred Strains; Motor Activity; Polymorphism, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Selective Serotonin Reuptake Inhibitors; Swimming; Tryptophan Hydroxylase; Vesicular Monoamine Transport Proteins | 2009 |
Contrasting effects of acute and chronic treatment with imipramine and fluoxetine on inhibitory avoidance and escape responses in mice exposed to the elevated T-maze.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Avoidance Learning; Escape Reaction; Fluoxetine; Imipramine; Male; Maze Learning; Mice; Motor Activity; Selective Serotonin Reuptake Inhibitors | 2009 |
Effects of antidepressants on GluR2 Q/R site-RNA editing in modified HeLa cell line.
Topics: Adenosine Deaminase; Amitriptyline; Amyotrophic Lateral Sclerosis; Antidepressive Agents; Arginine; Cyclopropanes; Desipramine; Fluoxetine; Fluvoxamine; Glutamine; HeLa Cells; Humans; Imipramine; Milnacipran; Morpholines; Paroxetine; Reboxetine; Receptors, AMPA; RNA Editing; RNA-Binding Proteins; RNA, Messenger | 2009 |
Influence of antidepressant drugs on Ecto-nucleotide pyrophosphatase/phosphodiesterases (E-NPPs) from salivary glands of rats.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cells, Cultured; Fluoxetine; Hydrolysis; Imipramine; Male; Moclobemide; Phosphoric Diester Hydrolases; Phosphorylation; Pyrophosphatases; Rats; Rats, Wistar; Salivary Proteins and Peptides; Submandibular Gland; Thymidine Monophosphate; Time Factors | 2009 |
Use of latency to immobility improves detection of antidepressant-like activity in the behavioral despair test in the mouse.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Fluoxetine; Imipramine; Immobilization; Male; Mice; Norepinephrine; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors; Sensitivity and Specificity; Species Specificity; Swimming | 2009 |
Fluoxetine (Prozac) binding to serotonin transporter is modulated by chloride and conformational changes.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Binding Sites; Chlorides; Cocaine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Fluoxetine; Ibogaine; Imipramine; Models, Chemical; Mutation; Protein Conformation; Protein Stability; Rats; RNA-Binding Proteins | 2009 |
Evaluating the role of the serotoninergic system in the control of human seminal vesicle smooth muscle-an in vitro approach.
Topics: Adrenergic alpha-Agonists; Aged; Clomipramine; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Ejaculation; Fluoxetine; Humans; Imipramine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Seminal Vesicles; Serotonin; Sexual Dysfunction, Physiological; Vas Deferens | 2009 |
Effects of fluoxetine and imipramine in rat fetuses treated during a critical gestational period: a macro and microscopic study.
Topics: Animals; Antidepressive Agents; Brain; Dopamine Uptake Inhibitors; Female; Fetal Weight; Fetus; Fluoxetine; Imipramine; Placenta; Pregnancy; Rats; Rats, Wistar | 2010 |
Sequential metabolism of secondary alkyl amines to metabolic-intermediate complexes: opposing roles for the secondary hydroxylamine and primary amine metabolites of desipramine, (s)-fluoxetine, and N-desmethyldiltiazem.
Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Desipramine; Diltiazem; Fluoxetine; Humans; Hydroxylamine; Hydroxylamines; Hydroxylation; Imipramine; Microsomes, Liver; Oxidoreductases, N-Demethylating; Steroid 16-alpha-Hydroxylase | 2010 |
Atypical anti-psychotics in delusional parasitosis: a retrospective case series of 20 patients.
Topics: Antipsychotic Agents; Benzodiazepines; Ectoparasitic Infestations; Female; Fluoxetine; Haloperidol; Humans; Imipramine; Male; Middle Aged; Olanzapine; Pimozide; Retrospective Studies; Risperidone; Schizophrenia, Paranoid; Sertraline | 2010 |
Interaction of selective serotonin reuptake inhibitors with neuronal nicotinic acetylcholine receptors.
Topics: Antidepressive Agents, Tricyclic; Fluoxetine; Humans; Imipramine; Ion Channels; Molecular Conformation; Neurons; Paroxetine; Receptors, Cholinergic; Receptors, Nicotinic; Selective Serotonin Reuptake Inhibitors | 2010 |
Quantitative determination of fluoxetine in human serum by high performance thin layer chromatography.
Topics: Antidepressive Agents, Second-Generation; Chromatography, Thin Layer; Fluoxetine; Humans; Imipramine; Limit of Detection; Molecular Structure; Reproducibility of Results | 2010 |
Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers.
Topics: Affect; Amitriptyline; Animals; Antidepressive Agents; Antimanic Agents; Benzodiazepines; Cerebral Cortex; Citalopram; Clorgyline; Cocaine; Cyclohexanols; Desipramine; Fluoxetine; Imipramine; In Vitro Techniques; Iproniazid; Lithium; Mianserin; Mirtazapine; Mitochondria; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Morpholines; Olanzapine; Pargyline; Reboxetine; Swine; Thiazepines; Valproic Acid; Venlafaxine Hydrochloride | 2010 |
Effect of fluoxetine or adenosine receptor NECA agonist on G-proteins of C6 glioma cells or NK immunocytes.
Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Antidepressive Agents, Tricyclic; Brain Neoplasms; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Fluoxetine; Glioma; GTP-Binding Proteins; Humans; Imipramine; Immunologic Factors; Interleukin-2; Killer Cells, Natural; Rats; Rats, Inbred F344; Selective Serotonin Reuptake Inhibitors; Signal Transduction | 2011 |
Serotonin-2C receptors in the basolateral nucleus of the amygdala mediate the anxiogenic effect of acute imipramine and fluoxetine administration.
Topics: Aminopyridines; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Anxiety Disorders; Avoidance Learning; Basolateral Nuclear Complex; Exploratory Behavior; Fluoxetine; Imipramine; Indoles; Male; Maze Learning; Neuropsychological Tests; Pyrazines; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2012 |
Influence of Neuropeptide Y and antidepressants upon cerebral monoamines involved in depression: an in vivo electrochemical study.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Anxiety; Arginine; Biogenic Monoamines; Biosensing Techniques; Brain Chemistry; Catecholamines; Depression; Electrochemistry; Fluoxetine; Imipramine; Indoles; Male; Neuropeptide Y; Neuropeptides; Oxidation-Reduction; Peptide Fragments; Rats; Rats, Wistar; Receptors, Neuropeptide Y; Selective Serotonin Reuptake Inhibitors | 2011 |
(S)- and (R)-fluoxetine as native markers in mass spectrometry (MS) binding assays addressing the serotonin transporter.
Topics: Cell Line; Chromatography, High Pressure Liquid; Fluoxetine; Humans; Imipramine; Kinetics; Protein Binding; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Tritium | 2011 |
The effects of neuropsychiatric drugs on glycogen synthase kinase-3 signaling.
Topics: Animals; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; beta Catenin; Blotting, Western; Brain; Clozapine; Fluoxetine; Glycogen Synthase Kinase 3; Haloperidol; Imipramine; Immunoprecipitation; Lithium; Male; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Valproic Acid | 2011 |
Antidepressants stimulate hippocampal neurogenesis by inhibiting p21 expression in the subgranular zone of the hipppocampus.
Topics: Animals; Antidepressive Agents; Blotting, Western; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Depression; Female; Fluoxetine; Hippocampus; Imipramine; Immunoenzyme Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; RNA, Small Interfering; Selective Serotonin Reuptake Inhibitors; Stem Cells; Swimming | 2011 |
Antidepressant-like effects of an alkaloid extract of the aerial parts of Annona cherimolia in mice.
Topics: Alkaloids; Animals; Annona; Antidepressive Agents; Behavior, Animal; Brain; Clomipramine; Dopamine; Fluoxetine; Herb-Drug Interactions; Homovanillic Acid; Hydroxyindoleacetic Acid; Imipramine; Male; Medicine, Traditional; Mexico; Mice; Plant Components, Aerial; Plant Extracts; Serotonin; Swimming | 2012 |
Uliginosin B, a phloroglucinol derivative from Hypericum polyanthemum: a promising new molecular pattern for the development of antidepressant drugs.
Topics: Animals; Antidepressive Agents; Benzazepines; Biogenic Monoamines; Bupropion; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fenclonine; Fluoxetine; Hypericum; Imipramine; Immobility Response, Tonic; Locomotion; Male; Mice; Mice, Inbred Strains; Phloroglucinol; Plant Extracts; Prazosin; Rats; Rats, Wistar; Receptors, Catecholamine; Sulpiride; Vesicular Monoamine Transport Proteins; Yohimbine | 2012 |
Pharmacophore modeling for hERG channel facilitation.
Topics: Animals; Atenolol; Chlorpheniramine; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoxetine; Haloperidol; Humans; Hydrophobic and Hydrophilic Interactions; Imipramine; Metoprolol; Nortriptyline; Potassium Channel Blockers; Promethazine; Propranolol; Quantitative Structure-Activity Relationship; Sotalol; Terfenadine; Verapamil; Xenopus laevis | 2012 |
Comparison of monoamine reuptake inhibitors for the immobility time and serotonin levels in the hippocampus and plasma of sub-chronically forced swim stressed rats.
Topics: Adrenergic Uptake Inhibitors; Animals; Cyclohexanols; Fluoxetine; Hippocampus; Imipramine; Immobilization; Male; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Stress, Psychological; Swimming; Venlafaxine Hydrochloride | 2012 |
Antidepressant effects of fibroblast growth factor-2 in behavioral and cellular models of depression.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Bromodeoxyuridine; Depressive Disorder; Disease Models, Animal; Fibroblast Growth Factor 2; Fluoxetine; Imipramine; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neuroglia; Prefrontal Cortex; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Fibroblast Growth Factor; Stress, Psychological | 2012 |
Antidepressants prevent hierarchy destabilization induced by lipopolysaccharide administration in mice: a neurobiological approach to depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cytokines; Depression; Disease Models, Animal; Fluoxetine; Humans; Imipramine; Lipopolysaccharides; Male; Mice; Serotonin; Social Behavior | 2012 |
Antidepressant-like effect of trans-resveratrol in chronic stress model: behavioral and neurochemical evidences.
Topics: Adrenal Glands; Animals; Antidepressive Agents; Body Weight; Brain; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Escape Reaction; Fluoxetine; Food Preferences; Gene Expression Regulation; Imipramine; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Stress, Psychological; Sucrose; Sweetening Agents; Time Factors; Water Deprivation | 2013 |
Direct alteration of a specific inhibitory circuit of the hippocampus by antidepressants.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Biogenic Monoamines; CA1 Region, Hippocampal; Data Interpretation, Statistical; Electroencephalography; Evoked Potentials; Excitatory Postsynaptic Potentials; Female; Fluoxetine; gamma-Aminobutyric Acid; Hippocampus; Imipramine; Inhibition, Psychological; Interneurons; Male; Nerve Net; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Selective Serotonin Reuptake Inhibitors; Synaptic Transmission | 2012 |
Ethopharmacological evaluation of the rat exposure test: a prey-predator interaction test.
Topics: Adrenergic alpha-2 Receptor Antagonists; Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents; Caffeine; Central Nervous System Stimulants; Diazepam; Escape Reaction; Factor Analysis, Statistical; Fluoxetine; Food Chain; Imipramine; Male; Mice; Motor Activity; Posture; Predatory Behavior; Rats; Rats, Long-Evans; Time Factors; Yohimbine | 2013 |
Sustained remission from depressive-like behavior depends on hippocampal neurogenesis.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Astrocytes; Behavior, Animal; Cell Proliferation; Conditioning, Psychological; Depression; Fluoxetine; Hippocampus; Imipramine; Male; Methylazoxymethanol Acetate; Neurogenesis; Neurons; Rats; Rats, Wistar; Stress, Psychological | 2013 |
Direct retino-raphe projection alters serotonergic tone and affective behavior.
Topics: Action Potentials; Affect; Animals; Behavior, Animal; Darkness; Fluoxetine; Gerbillinae; Imipramine; Male; Neural Pathways; Raphe Nuclei; Retinal Ganglion Cells; Serotonin | 2013 |
Effect of newly synthesized 1,2,4-triazino[5,6-b]indole-3-thione derivatives on olfactory bulbectomy induced depression in rats.
Topics: Acetamides; Acetanilides; Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fluoxetine; Imipramine; Male; Moclobemide; Olfaction Disorders; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Triazines | 2012 |
A proposal for refining the forced swim test in Swiss mice.
Topics: Animals; Antidepressive Agents; Apomorphine; Caffeine; Central Nervous System Stimulants; Desipramine; Disease Models, Animal; Fluoxetine; Imipramine; Immobility Response, Tonic; Male; Mice; Principal Component Analysis; Swimming; Time Factors | 2013 |
Stress-induced anhedonia is associated with hypertrophy of medium spiny neurons of the nucleus accumbens.
Topics: Anhedonia; Animals; Antidepressive Agents; Behavior, Animal; Fluoxetine; Hypertrophy; Imipramine; Male; Nucleus Accumbens; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Stress, Psychological | 2013 |
[Antidepressant properties of beta-phenylglutamic acid hydrochloride (RGPU-135, glutarone) in comparison to imipramine, tianeptine, and fluoxetine].
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Behavior, Animal; Fluoxetine; Glutamic Acid; Imipramine; Male; Mice; Rats; Thiazepines | 2013 |
5-HT1A and 5-HT2A receptor control of a panic-like defensive response in the rat dorsomedial hypothalamic nucleus.
Topics: Animals; Dorsomedial Hypothalamic Nucleus; Electric Stimulation; Escape Reaction; Fluoxetine; Imipramine; Male; Panic; Periaqueductal Gray; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2013 |
In silico study on the inhibitory interaction of drugs with wild-type CYP2D6.1 and the natural variant CYP2D6.17.
Topics: Cocaine; Computer Simulation; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Enzyme Inhibitors; Fluoxetine; Imipramine; Molecular Docking Simulation; Molecular Dynamics Simulation; Organic Chemicals; Polymorphism, Genetic; Protein Conformation; Quinidine; Regression Analysis; Stereoisomerism; Thioridazine | 2014 |
Human P-glycoprotein differentially affects antidepressant drug transport: relevance to blood-brain barrier permeability.
Topics: Amitriptyline; Animals; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Capillary Permeability; Dogs; Duloxetine Hydrochloride; Fluoxetine; Humans; Imipramine; Madin Darby Canine Kidney Cells; Mianserin; Mirtazapine; Thiophenes; Transfection | 2013 |
Antidepressants share the ability to increase catecholamine output in the bed nucleus of stria terminalis: a possible role in antidepressant therapy?
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bupropion; Citalopram; Desipramine; Dopamine; Dose-Response Relationship, Drug; Fluoxetine; Imipramine; Male; Morpholines; Norepinephrine; Rats, Sprague-Dawley; Reboxetine; Septal Nuclei; Time Factors | 2014 |
Involvement of 5-HT2C and 5-HT1A receptors of the basolateral nucleus of the amygdala in the anxiolytic effect of chronic antidepressant treatment.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Anxiety; Avoidance Learning; Exploratory Behavior; Fluoxetine; Imipramine; Male; Maze Learning; Panic; Piperazines; Pyrazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists | 2014 |
Effects of antidepressant drugs on synaptic protein levels and dendritic outgrowth in hippocampal neuronal cultures.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cell Enlargement; Cells, Cultured; Citalopram; Dendrites; Fluoxetine; Hippocampus; Imipramine; Nerve Tissue Proteins; Neurons; Paroxetine; Rats; Rats, Sprague-Dawley; Sertraline; Thiazepines; Tranylcypromine | 2014 |
Effects of antidepressant drug exposure on gene expression in the developing cerebral cortex.
Topics: Animals; Antidepressive Agents; Cerebral Cortex; Fluoxetine; Imipramine; Male; Rats; Rats, Sprague-Dawley; Transcriptome | 2014 |
Lower cortical serotonin 2A receptors in major depressive disorder, suicide and in rats after administration of imipramine.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Cerebral Cortex; Depressive Disorder, Major; Female; Fluoxetine; Frontal Lobe; Gyrus Cinguli; Humans; Imipramine; Male; Middle Aged; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Suicide; Young Adult | 2014 |
Antidepressant properties of aqueous macerate from Gladiolus dalenii corms.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Depression; Fluoxetine; Hindlimb Suspension; Imipramine; Iridaceae; Male; Medicine, African Traditional; Mice; Motor Activity; N-Methylaspartate; Phytotherapy; Plant Extracts; Receptors, N-Methyl-D-Aspartate; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Swimming | 2014 |
Antidepressants that inhibit both serotonin and norepinephrine reuptake impair long-term potentiation in hippocampus.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cyclohexanols; Fluoxetine; Hippocampus; Imipramine; Long-Term Potentiation; Male; Maprotiline; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptic Transmission; Venlafaxine Hydrochloride | 2014 |
Imipramine and fluoxetine inhibit LPS-induced activation and affect morphology of microglial cells in the rat glial culture.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Cells, Cultured; Fluoxetine; Imipramine; Interleukin-1beta; Lipopolysaccharides; Microglia; Rats; Rats, Wistar; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2014 |
Plurality of anxiety and depression alteration mechanism by oleanolic acid.
Topics: alpha-Methyltyrosine; Animals; Anti-Anxiety Agents; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Fenclonine; Fluoxetine; Hippocampus; Imipramine; Male; Mice; Monoamine Oxidase; Motor Activity; Oleanolic Acid; Pentylenetetrazole; Piperazines; Pyridines | 2014 |
Pramipexole but not imipramine or fluoxetine reverses the "depressive-like" behaviour in a rat model of preclinical stages of Parkinson's disease.
Topics: Animals; Antidepressive Agents; Benzothiazoles; Depression; Disease Models, Animal; Dopamine Agonists; Fluoxetine; Imipramine; Male; Motor Activity; Oxidopamine; Parkinson Disease; Pramipexole; Rats; Rats, Wistar; Swimming; Treatment Outcome | 2014 |
Effects of aspirin on immobile behavior and endocrine and immune changes in the forced swimming test: comparison to fluoxetine and imipramine.
Topics: Animals; Antidepressive Agents; Aspirin; Behavior, Animal; Corticosterone; Endocrine Glands; Fluoxetine; Imipramine; Immune System; Interleukin-6; Male; Rats; Rats, Sprague-Dawley; Swimming; Tumor Necrosis Factor-alpha | 2014 |
Differential and converging molecular mechanisms of antidepressants' action in the hippocampal dentate gyrus.
Topics: Acetamides; Animals; Antidepressive Agents; Chronic Disease; Dentate Gyrus; Depressive Disorder; Disease Models, Animal; Fluoxetine; Gene Expression; Imipramine; Male; Neurons; Random Allocation; Rats, Wistar; Stress, Psychological; Thiazepines; Uncertainty | 2015 |
Lithium prevents aberrant NMDA-induced F-actin reorganization in neurons.
Topics: Actins; Animals; Antidepressive Agents; Antipsychotic Agents; Cells, Cultured; Cytoskeleton; Dendrites; Dose-Response Relationship, Drug; Fluoxetine; Glycogen Synthase Kinase 3; Hippocampus; Imipramine; Lithium Chloride; N-Methylaspartate; Neurons; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Time Factors | 2014 |
The effects of ifenprodil on the activity of antidepressant drugs in the forced swim test in mice.
Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Drug Synergism; Fluoxetine; Imipramine; Mice; Morpholines; Piperidines; Reboxetine; Swimming; Thiazepines | 2014 |
Influence of enrichment on behavioral and neurogenic effects of antidepressants in Wistar rats submitted to repeated forced swim test.
Topics: Animals; Antidepressive Agents; Depressive Disorder; Disease Models, Animal; Environment; Fluoxetine; Hippocampus; Imipramine; Injections, Intraperitoneal; Male; Motor Activity; Neural Stem Cells; Neurogenesis; Psychological Tests; Random Allocation; Rats, Wistar; Swimming | 2015 |
Impact of antidepressant therapy on cognitive aspects of work, condom use, and psychosocial well-being among HIV clients in Uganda.
Topics: Adult; Antidepressive Agents; Cognition Disorders; Condoms; Depressive Disorder, Major; Developing Countries; Disability Evaluation; Employment; Female; Fluoxetine; Follow-Up Studies; Health Behavior; HIV Infections; Humans; Imipramine; Internal-External Control; Male; Middle Aged; Quality of Life; Self Efficacy; Social Stigma; Uganda | 2014 |
Agmatine enhances antidepressant potency of MK-801 and conventional antidepressants in mice.
Topics: Agmatine; Animals; Antidepressive Agents; Bupropion; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Female; Fluoxetine; Hindlimb Suspension; Imipramine; Mice; Motor Activity | 2015 |
Impramine, fluoxetine and clozapine differently affected reactivity to positive and negative stimuli in a model of motivational anhedonia in rats.
Topics: Anhedonia; Animals; Antidepressive Agents; Antipsychotic Agents; Clozapine; Dietary Sucrose; Disease Models, Animal; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Eating; Fluoxetine; Haloperidol; Imipramine; Lithium Compounds; Male; Motivation; Nucleus Accumbens; Phosphorylation; Rats, Sprague-Dawley; Stress, Psychological | 2015 |
The effects of antidepressants "fluoxetine and imipramine" on vascular abnormalities and Toll like receptor-4 expression in diabetic and non-diabetic rats exposed to chronic stress.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Blood Glucose; Blood Pressure; Blood Vessels; Body Weight; Chronic Disease; Diabetes Mellitus, Experimental; Fluoxetine; Imipramine; Insulin; Lipids; Male; Rats; Rats, Wistar; Stress, Physiological; Toll-Like Receptor 4 | 2015 |
Chronic administration of anticonvulsants but not antidepressants impairs bone strength: clinical implications.
Topics: Animals; Anticonvulsants; Antidepressive Agents; Bone and Bones; Bone Density; Carbamazepine; Femur; Fluoxetine; Imipramine; Male; Rats; Rats, Sprague-Dawley; Valproic Acid; X-Ray Microtomography | 2015 |
The positive effect on ketamine as a priming adjuvant in antidepressant treatment.
Topics: Animals; Antidepressive Agents; Anxiety; Aspartic Acid; Behavior, Animal; Brain; Depression; Depressive Disorder, Major; Disease Models, Animal; Drug Therapy, Combination; Fluoxetine; Glutamic Acid; Imipramine; Ketamine; Male; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Wistar; Stress, Psychological | 2015 |
Doxepin and imipramine but not fluoxetine reduce the activity of the rat glutamate transporter EAAT3 expressed in Xenopus oocytes.
Topics: Animals; Antidepressive Agents; Dose-Response Relationship, Drug; Doxepin; Excitatory Amino Acid Transporter 3; Female; Fluoxetine; Glutamic Acid; Imipramine; Oocytes; Protein Kinase C; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Xenopus laevis | 2015 |
Chronic stress and antidepressant induced changes in Hdac5 and Sirt2 affect synaptic plasticity.
Topics: Adult; Animals; Antidepressive Agents; Chronic Disease; Depressive Disorder; Fluoxetine; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Imipramine; Male; Mice, Inbred C57BL; Middle Aged; Morpholines; Neuronal Plasticity; Prefrontal Cortex; Reboxetine; RNA, Messenger; Sirtuins; Stress, Psychological | 2015 |
Changes in Muscarinic M2 Receptor Levels in the Cortex of Subjects with Bipolar Disorder and Major Depressive Disorder and in Rats after Treatment with Mood Stabilisers and Antidepressants.
Topics: Animals; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cerebral Cortex; Depressive Disorder, Major; Disease Models, Animal; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Muscarinic Agonists; Oxotremorine; Pirenzepine; Radiopharmaceuticals; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Tritium | 2016 |
Lower [3H]LY341495 binding to mGlu2/3 receptors in the anterior cingulate of subjects with major depressive disorder but not bipolar disorder or schizophrenia.
Topics: Amino Acids; Animals; Antidepressive Agents; Bipolar Disorder; Brain; Depressive Disorder, Major; Excitatory Amino Acid Antagonists; Female; Fluoxetine; Gyrus Cinguli; Humans; Imipramine; Male; Middle Aged; Radioligand Assay; Radionuclide Imaging; Rats; Receptors, Metabotropic Glutamate; Schizophrenia; Tritium; Xanthenes | 2016 |
The Role of Nitric Oxide in the Antidepressant Actions of 5-Aminoimidazole-4-Carboxamide-1-β-D-Ribofuranoside in Insulin-Resistant Mice.
Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Antidepressive Agents; Combined Modality Therapy; Corticosterone; Depressive Disorder; Diet, High-Fat; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Activation; Fluoxetine; Imipramine; Insulin Resistance; Ketamine; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Physical Conditioning, Animal; Prefrontal Cortex; Ribonucleotides; Triazenes | 2016 |
Antidepressants differentially affect striatal amphetamine-stimulated dopamine and serotonin release in rats with high and low novelty-oriented behaviour.
Topics: Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Corpus Striatum; Dopamine; Fluoxetine; Imipramine; Male; Microdialysis; Morpholines; Rats; Rats, Wistar; Reboxetine; Selective Serotonin Reuptake Inhibitors; Serotonin | 2016 |
Traxoprodil, a selective antagonist of the NR2B subunit of the NMDA receptor, potentiates the antidepressant-like effects of certain antidepressant drugs in the forced swim test in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Fluoxetine; Imipramine; Mice; Motor Activity; Piperidines; Receptors, N-Methyl-D-Aspartate; Swimming; Treatment Outcome | 2016 |
Comparison of the Efficiency of Adeprophen and Antidepressants of Various Groups on the Model of Reserpine-Induced Depression in Rats.
Topics: Adenine; Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Fluoxetine; Food Preferences; Imipramine; Male; Motor Activity; Paroxetine; Rats; Reserpine; Sertraline; Venlafaxine Hydrochloride | 2016 |
Repeatedly administered antidepressant drugs modulate humoral and cellular immune response in mice through action on macrophages.
Topics: Animals; Antidepressive Agents; Biomarkers; Cytokines; Depressive Disorder; Dermatitis, Contact; Fluoxetine; Imipramine; Immunity, Cellular; Immunity, Humoral; Immunosuppression Therapy; Injections, Intraperitoneal; Macrophages; Male; Mice; Mice, Inbred Strains; Moclobemide; Venlafaxine Hydrochloride | 2016 |
Fourteen-day administration of corticosterone may induce detrusor overactivity symptoms.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Depression; Disease Models, Animal; Female; Fluoxetine; Imipramine; Muscarinic Antagonists; Random Allocation; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Selective Serotonin Reuptake Inhibitors; Urinary Bladder; Urinary Bladder, Overactive | 2016 |
The effect of Schisandra chinensis extracts on depression by noradrenergic, dopaminergic, GABAergic and glutamatergic systems in the forced swim test in mice.
Topics: Adrenergic Neurons; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Dopaminergic Neurons; Dose-Response Relationship, Drug; Fluoxetine; GABAergic Neurons; Imipramine; Male; Mice; Physical Conditioning, Animal; Plant Extracts; Schisandra | 2016 |
Antidepressant drugs can modify cytotoxic action of temozolomide.
Topics: Antidepressive Agents; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell Survival; Dacarbazine; Depression; Drug Interactions; Fluoxetine; Glioblastoma; Humans; Imipramine; Temozolomide; Tranylcypromine; Tumor Hypoxia | 2017 |
Regulation of insulin receptor phosphorylation in the brains of prenatally stressed rats: New insight into the benefits of antidepressant drug treatment.
Topics: Animals; Antidepressive Agents; Brain; Depressive Disorder; Female; Fluoxetine; Gene Expression; Imipramine; Insulin; Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats, Sprague-Dawley; Receptor, Insulin; RNA, Messenger; Stress, Psychological; Thiazepines | 2017 |
Adult hippocampal neuroplasticity triggers susceptibility to recurrent depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depressive Disorder; Disease Models, Animal; Disease Susceptibility; Fluoxetine; Hippocampus; Imipramine; Male; Neuronal Plasticity; Rats; Rats, Wistar; Recurrence; Stress, Psychological | 2017 |
Evaluation of the effectiveness of chronic antidepressant drug treatments in the hippocampal mitochondria - A proteomic study in an animal model of depression.
Topics: 14-3-3 Proteins; Animals; Antidepressive Agents; Cathepsin D; COP9 Signalosome Complex; Depression; Disease Models, Animal; Dynamins; Electron Transport Complex III; Female; Fluoxetine; Hippocampus; Imipramine; Immobility Response, Tonic; Male; Mitochondria; Pregnancy; Prenatal Exposure Delayed Effects; Protein Deglycase DJ-1; Proteome; Proteomics; Rats; Stathmin; Stress, Psychological | 2017 |
Mitochondrial proteomics investigation of frontal cortex in an animal model of depression: Focus on chronic antidepressant drugs treatment.
Topics: Animals; Antidepressive Agents; Depression; Depressive Disorder; Disease Models, Animal; Female; Fluoxetine; Frontal Lobe; Imipramine; Male; Mitochondria; Pregnancy; Prenatal Exposure Delayed Effects; Proteome; Proteomics; Rats; Rats, Sprague-Dawley | 2018 |
Nucleocytoplasmic export of HDAC5 and SIRT2 downregulation: two epigenetic mechanisms by which antidepressants enhance synaptic plasticity markers.
Topics: Animals; Antidepressive Agents; Down-Regulation; Epigenesis, Genetic; Fluoxetine; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Imipramine; Male; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Prefrontal Cortex; Random Allocation; Reboxetine; Sirtuin 2 | 2018 |
Derivatization of common antidepressant drugs increases inhibition of acid sphingomyelinase and reduces induction of phospholipidosis.
Topics: Antidepressive Agents; Cell Line, Tumor; Desipramine; Fluoxetine; Humans; Imipramine; Lysosomes; Phospholipids; Sphingomyelin Phosphodiesterase | 2018 |
Irinotecan Alters the Disposition of Morphine Via Inhibition of Organic Cation Transporter 1 (OCT1) and 2 (OCT2).
Topics: Amitriptyline; Animals; Drug Interactions; Fluoxetine; HEK293 Cells; Humans; Imipramine; Irinotecan; Mice, Inbred C57BL; Morphine; Narcotics; Ondansetron; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Tissue Distribution; Verapamil | 2018 |
Antidepressants with different mechanisms of action show different chronopharmacological profiles in the tail suspension test in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Bupropion; Circadian Rhythm; Depression; Dopamine; Fluoxetine; Imipramine; Male; Mice; Mice, Inbred C57BL; Movement; Norepinephrine; Time Factors; Venlafaxine Hydrochloride | 2019 |
Neuronal life or death linked to depression treatment: the interplay between drugs and their stress-related outcomes relate to single or combined drug therapies.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cell Cycle Checkpoints; Depression; Fluoxetine; Hippocampus; Imipramine; Mice; Neurons | 2019 |
White Environment Can Be Used as an Aversive Stimulus in Zebrafish Inhibitory Avoidance Learning.
Topics: Animals; Antidepressive Agents, Tricyclic; Avoidance Learning; Female; Fluoxetine; Imipramine; Male; Maze Learning; Selective Serotonin Reuptake Inhibitors; Zebrafish | 2019 |
MicroRNA profiling identifies a novel compound with antidepressant properties.
Topics: Animals; Antidepressive Agents; Brain Injuries, Traumatic; Computational Biology; Depression; Disease Models, Animal; Estradiol; Fluoxetine; Gene Expression Regulation; Hippocampus; Humans; Imipramine; MicroRNAs; Rats; Sertraline; Sulfonamides; Thiazoles | 2019 |
Effects of the adjunctive treatment of antidepressants with opiorphin on a panic-like defensive response in rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Fluoxetine; Imipramine; Male; Maze Learning; Neprilysin; Oligopeptides; Panic Disorder; Periaqueductal Gray; Protease Inhibitors; Rats; Rats, Wistar; Salivary Proteins and Peptides | 2020 |
Involvement of monoaminergic targets in the antidepressant- and anxiolytic-like effects of the synthetic alkamide riparin IV: Elucidation of further mechanisms through pharmacological, neurochemistry and computational approaches.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Brain; Bupropion; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Imipramine; Mice; Molecular Docking Simulation; Monoamine Oxidase; Norepinephrine; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-2; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, GABA-A; Receptors, Serotonin; Receptors, Serotonin, 5-HT2; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tyramine | 2020 |
mGluR5 mediates ketamine antidepressant response in susceptible rats exposed to prenatal stress.
Topics: Animals; Antidepressive Agents; Depression; Fluoxetine; Imipramine; Ketamine; Rats | 2020 |
Intermittent repeated stress but not ketamine changes mice response to antidepressants.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Behavior, Animal; Fluoxetine; Imipramine; Ketamine; Male; Mice; Stress, Psychological | 2021 |
Antidepressants Differentially Regulate Intracellular Signaling from α1-Adrenergic Receptor Subtypes In Vitro.
Topics: Animals; Antidepressive Agents; Citalopram; Depression; Desipramine; Fluoxetine; Gene Expression Regulation; Humans; Imipramine; Mianserin; Mice; PC12 Cells; Rats; Reboxetine; Receptors, Adrenergic, alpha-1; Signal Transduction | 2021 |
Chronic antidepressant treatment rescues abnormally reduced REM sleep theta power in socially defeated rats.
Topics: Animals; Antidepressive Agents; Chronic Disease; Electroencephalography; Fluoxetine; Humans; Imipramine; Male; Rats; Sleep, REM; Stress, Psychological; Theta Rhythm | 2021 |
Molecular Consequences of Depression Treatment: A Potential In Vitro Mechanism for Antidepressants-Induced Reprotoxic Side Effects.
Topics: Amitriptyline; Animals; Antidepressive Agents; Antipsychotic Agents; Cell Line; Escitalopram; Fluoxetine; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation; Imipramine; Male; Mice; Micronuclei, Chromosome-Defective; Mirtazapine; Models, Biological; Olanzapine; Organ Specificity; Reboxetine; Reproduction; Signal Transduction; Spermatogenesis; Telomeric Repeat Binding Protein 1; Telomeric Repeat Binding Protein 2; Time Factors; Venlafaxine Hydrochloride | 2021 |
Investigation of Cochlospermum religiosum leaves for antidepressant and anxiolytic activities and its synergistic effect with imipramine and fluoxetine.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Bixaceae; Depression; Fluoxetine; Imipramine; Mice; Motor Activity; Plant Extracts; Rats; Reserpine | 2022 |
Decreased sensitivity to antidepressant drugs in Wistar Hannover rats submitted to two animal models of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Escitalopram; Fluoxetine; Imipramine; Models, Animal; Rats; Rats, Wistar; Swimming | 2023 |
A comparative analysis of depressive-like behavior: Exploring sex-related differences and insights.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Female; Fluoxetine; Hindlimb Suspension; Imipramine; Male; Mice; Swimming | 2023 |