imipramine and disulfiram

imipramine has been researched along with disulfiram in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199014 (56.00)18.7374
1990's4 (16.00)18.2507
2000's0 (0.00)29.6817
2010's7 (28.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Kayser, C1
Kissin, B1
Barnhill, J; Boxenbaum, H; Ciraulo, DA1
Kadzielawa, K; Widy-Tyszkiewicz, E1
Dandiya, PC; Kulkarni, SK1
Gross, MM; Kissin, B1
Bhagat, B; Gilliam, J1
Presthus, J1
Chaftez, ME1
Haefely, W1
Kadzielawa, K; Widy, E1
Kariya, T; Kobayashi, K; Kobayashi, T; Nagao, Y; Takahashi, R; Takamizawa, M; Toru, M; Tsuchiya, K1
Olesen, OV1
Amabeoku, G; Chandomba, R1
Harrison, W; McGrath, PJ; Nunes, EV; Ocepek-Welikson, K; Quitkin, FM; Stewart, JP; Tricamo, E1
Amabeoku, GJ; Syce, JA1
Chabac, S; Durbin, P; Houin, G; Hulot, T; Potgieter, A; Saivin, S1
ALHA, AR; LEVONEN, E; MUKULA, AL; RUOHONEN, A; SALOMAA, E; TAMMINEN, V1

Reviews

5 review(s) available for imipramine and disulfiram

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Other trials with drug therapy in parkinsonism].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Oct-10, Volume: 93, Issue:28

    Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Dihydroxyphenylalanine; Disulfiram; Drug Evaluation; Drug Therapy, Combination; Humans; Imipramine; Methyldopa; Monoamine Oxidase Inhibitors; Parkinson Disease; Picolinic Acids; Rats; Serine; Time Factors; Tryptophan; Tyrosine

1973
Drugs in the treatment of alcoholism.
    The Medical clinics of North America, 1967, Volume: 51, Issue:5

    Topics: Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Amitriptyline; Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Disulfiram; Humans; Imipramine; Metronidazole; Tranquilizing Agents

1967
[Drugs with effect on the adrenergic nerve fiber].
    Pharmaceutica acta Helvetiae, 1968, Volume: 43, Issue:12

    Topics: Aminocaproates; Amitriptyline; Amphetamine; Bretylium Compounds; Chlorpromazine; Disulfiram; Dopamine; Ephedrine; Guanethidine; Humans; Imipramine; Mental Disorders; Metaraminol; Methyldopa; Methyltyrosines; Monoamine Oxidase Inhibitors; Neurons; Norepinephrine; Octopamine; Prenylamine; Reserpine; Sympathetic Nervous System; Sympathomimetics; Tetrabenazine; Tyramine; Vascular Diseases

1968
Clinical pharmacokinetics of acamprosate.
    Clinical pharmacokinetics, 1998, Volume: 35, Issue:5

    Topics: Acamprosate; Age Factors; Alcohol Deterrents; Animals; Desipramine; Diazepam; Disulfiram; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Food-Drug Interactions; Humans; Imipramine; Psychotropic Drugs; Sex Characteristics; Taurine

1998

Trials

1 trial(s) available for imipramine and disulfiram

ArticleYear
Imipramine treatment of alcoholism with comorbid depression.
    The American journal of psychiatry, 1993, Volume: 150, Issue:6

    Topics: Adult; Affect; Alcohol Drinking; Alcoholism; Comorbidity; Depressive Disorder; Disulfiram; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Panic Disorder; Pilot Projects; Placebos; Recurrence; Research Design

1993

Other Studies

19 other study(ies) available for imipramine and disulfiram

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[Analysis of the circadian rhythm of motor activity in white rats by using several pharmacologic agents which act on cerebral monoamines].
    Archives internationales de physiologie et de biochimie, 1978, Volume: 86, Issue:5

    Topics: Animals; Brain; Circadian Rhythm; Disulfiram; Fenclonine; Imipramine; Motor Activity; Nialamide; Norepinephrine; Rats; Reserpine; Serotonin; Sleep Stages

1978
The use of psychoactive drugs in the long-term treatment of chronic alcoholics.
    Annals of the New York Academy of Sciences, 1975, Apr-25, Volume: 252

    Topics: Alcoholism; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Chronic Disease; Depression; Diazepam; Disulfiram; Drug Synergism; Drug Therapy, Combination; Humans; Imipramine; Mental Disorders; New York City; Patient Acceptance of Health Care; Psychotherapy; Substance Withdrawal Syndrome; Substance-Related Disorders; Thioridazine

1975
Pharmacokinetic interaction of disulfiram and antidepressants.
    The American journal of psychiatry, 1985, Volume: 142, Issue:11

    Topics: Adult; Alcoholism; Desipramine; Disulfiram; Drug Interactions; Half-Life; Humans; Hydroxylation; Imipramine; Kinetics; Male; Middle Aged

1985
The influence of various pharmacological agents on the desynchronization produced by DOPA in the cerveau isolé preparation.
    Electroencephalography and clinical neurophysiology, 1970, Volume: 28, Issue:3

    Topics: Animals; Cats; Chlorpromazine; Decerebrate State; Dihydroxyphenylalanine; Disulfiram; Electroencephalography; Heart Rate; Hydrazines; Imipramine; Phenoxybenzamine; Phentolamine; Propranolol; Reserpine

1970
On the mechanism of potentiation of amphetamine induced stereotype behaviour by imipramine.
    Psychopharmacologia, 1972, Volume: 27, Issue:4

    Topics: Amphetamine; Animals; Behavior, Animal; Brain; Catecholamines; Disulfiram; Drug Synergism; Fenclonine; Humans; Imipramine; Male; Methyltyrosines; Rats; Stereotyped Behavior

1972
Drug therapy in alcoholism.
    Current psychiatric therapies, 1970, Volume: 10

    Topics: Adult; Alcoholic Intoxication; Alcoholism; Antidepressive Agents; Anxiety; Carbamates; Chlordiazepoxide; Chronic Disease; Depression; Disulfiram; Female; Humans; Imipramine; Male; Metronidazole; Pentobarbital; Psychoses, Alcoholic; Sleep, REM; Substance Withdrawal Syndrome; Tranquilizing Agents

1970
Effect of various procedures on the repletion of cardiac catecholamine stores after tyramine.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 150, Issue:1

    Topics: Adrenal Medulla; Animals; Bretylium Compounds; Cocaine; Disulfiram; Enzymes; Hydrazines; Imipramine; In Vitro Techniques; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; Radiometry; Rats; Tritium; Tyramine

1965
The influence of imipramine on the central effects of dihydroxyphenylalanine.
    Neuropharmacology, 1970, Volume: 9, Issue:5

    Topics: Animals; Blood Pressure; Brain; Cats; Chlorpromazine; Dihydroxyphenylalanine; Disulfiram; Electrodes; Electroencephalography; Gallamine Triethiodide; Heart Rate; Imipramine; Phenoxybenzamine; Phentolamine; Propranolol; Pupil; Rabbits; Reserpine

1970
Catecholamine metabolism of manic-depressive illness.
    Journal of psychiatric research, 1968, Volume: 6, Issue:3

    Topics: Antidepressive Agents; Bipolar Disorder; Calcium; Catecholamines; Creatinine; Disulfiram; Dopamine; Epinephrine; Humans; Hydroxyindoleacetic Acid; Imipramine; Male; Methyldopa; Middle Aged; Norepinephrine; Phenylacetates; Psychiatric Status Rating Scales; Vanilmandelic Acid

1968
The influence of disulfiram and calcium carbimide on the serum diphenylhydantoin. Excretion of HPPH in the urine.
    Archives of neurology, 1967, Volume: 16, Issue:6

    Topics: Acetazolamide; Adult; Aged; Alcoholism; Amitriptyline; Chlordiazepoxide; Chlorpromazine; Chromatography, Thin Layer; Cyanates; Disulfiram; Drug Synergism; Epilepsy; Humans; Hydroflumethiazide; Imipramine; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone

1967
Strychnine-induced seizures in mice: the role of noradrenaline.
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Disulfiram; Droxidopa; Idazoxan; Imipramine; Male; Mice; Pargyline; Phentolamine; Prazosin; Propranolol; Receptors, Adrenergic; Reserpine; Seizures; Strychnine

1994
Propranolol-induced seizures in mice: the role of noradrenaline.
    Cellular and molecular life sciences : CMLS, 1997, Volume: 53, Issue:8

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic Uptake Inhibitors; alpha-Methyltyrosine; Animals; Disulfiram; Droxidopa; Drug Synergism; Female; Imipramine; Isoproterenol; Male; Mice; Norepinephrine; Pargyline; Propranolol; Reserpine; Seizures

1997
[Ultra red spectroscopy in forensic chemical analysis. II. Chemical investigation in 4 fatalities: 1. Tofranil poisoning, and combination poisonings, 2. Parathion and Endrin, 3. Nicotine and parathion and 4. Pentymal, disulfiram and ethanol].
    Archiv fur Toxikologie, 1960, Volume: 18

    Topics: Amobarbital; Disulfiram; Endrin; Ethanol; Imipramine; Nicotine; Parathion; Poisoning; Spectrum Analysis

1960