imipramine and diphenhydramine

imipramine has been researched along with diphenhydramine in 74 studies

Research

Studies (74)

Timeframe	Studies, this research(%)	All Research%
pre-1990	38 (51.35)	18.7374
1990's	2 (2.70)	18.2507
2000's	19 (25.68)	29.6817
2010's	14 (18.92)	24.3611
2020's	1 (1.35)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Strassburg, CP; Tukey, RH	1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Akazawa, M; Inui, K; Masuda, S; Okuda, M; Saito, H; Urakami, Y	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Keserü, GM	1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Caron, G; Ermondi, G	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Jia, L; Sun, H	1
Alimuddin, M; Bulloch, D; Dahl, R; Grant, D; Lee, N; Peacock, M	1
Ahman, M; Holmén, AG; Wan, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Gozalbes, R; Pineda-Lucena, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Sen, S; Sinha, N	1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Huh, K; Iwata, H; Yamamoto, I	1
Gol'dovskaia, IL	1
Drew, R; Gram, TE; Siddik, ZH	1
White, JH	1
Hata, T; Hoshino, K; Kita, T; Okage, T; Yoneda, R	1
García Rodríguez, M	1
Todorov, S	1
Arita, T; Kawai, S; Miyazaki, K; Saitoh, H	1
Kameyama, T; Nagasaka, M; Yamada, K	1
el-Darawy, ZI; Mobarak, ZM	1
Bell, S; Jhamandas, K; Sutak, M	1
Kessell, A; Williams, AG	1
Hartmann, E	1
Bogaert, MG; Willems, JL	1
Gyermek, L; Hill, RT; Sigg, EB	1
Lish, PM; Peters, EL; Robbins, SI	1
Colson, SH; Tolson, WW; Umberger, EJ	1
Saarnivaara, L	1
Hata, T; Kita, T; Murakami, T	2
Schrold, J	1
Hartvig, P; Vessman, J	1
Connor, JD; Crawford, IL; Pardridge, WM	1
Gordon, JL	1
Aihara, H; Miyauchi, T; Ozawa, H; Sasajima, M; Sugawara, K	1
Vaillant, GE	2
Florio, V; Longo, VG	1
De Carolis, AS; Loizzo, A; Longo, VG	1
Gross, R; Linker, H; Reuter, H	1
Kuroume, T; Matsumura, T; Tajima, S	1
Brody, TM; McNeill, JH	1
Bhargava, LP; Dandiya, PC	1
Ibrahim, I; Sulman, FG; Weller, CP	1
Michal, F; Penglis, F	1
Bahn, S; Winer, JA	1
Kuo, CC	1
Kuo, CC; Yang, YC	1
LEME, JG; ROCHAESILVA, M	1
GUNDLACH, RH; HANKOFF, LD; PALEY, HM; RUDORFER, L	1
Finel, M; Fukami, T; Izukawa, T; Kato, Y; Nakajima, M; Oda, S; Yokoi, T	1
Quirino, JP; Wuethrich, A	1
Ansari, S; Brockmöller, J; Doetsch, DA; Jensen, O; Sachkova, A	1

Reviews

4 review(s) available for imipramine and diphenhydramine

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Psychotropic therapy and intraocular pressure]. Oftalmologicheskii zhurnal, 1975, Volume: 30, Issue:1 Topics: Amitriptyline; Analgesics; Antidepressive Agents; Chlorpromazine; Diazepam; Diphenhydramine; Eye Diseases; Glaucoma; Histamine H1 Antagonists; Humans; Imipramine; Intraocular Pressure; Lithium; Mental Disorders; Mephenesin; Meprobamate; Piperidines; Psychotropic Drugs; Secologanin Tryptamine Alkaloids; Tranquilizing Agents; Trihexyphenidyl	1975
Pharmacological studies of sleep and dreaming: chemical and clinical relationships. Biological psychiatry, 1969, Volume: 1, Issue:3 Topics: Amitriptyline; Amphetamine; Antidepressive Agents; Atropine; Chloralose; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Diazepam; Diphenhydramine; Dreams; Glutethimide; Humans; Hypnotics and Sedatives; Imipramine; Lysergic Acid Diethylamide; Meprobamate; Methaqualone; Morphine; Nialamide; Pentobarbital; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tranylcypromine; Triiodothyronine; Tryptophan	1969

Other Studies

70 other study(ies) available for imipramine and diphenhydramine

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Predicting blood-brain barrier permeation from three-dimensional molecular structure. Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11 Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules. Pharmaceutical research, 2001, Volume: 18, Issue:11 Topics: Animals; Cell Line; Dogs; Kidney; Kidney Tubules; Kinetics; Membranes; Nephrons; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substrate Specificity; Tetraethylammonium; Transfection	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Determination of log D via automated microfluidic liquid-liquid extraction. Journal of medicinal chemistry, 2008, Aug-28, Volume: 51, Issue:16 Topics: Automation; Biopharmaceutics; Microfluidic Analytical Techniques; Pharmacokinetics	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
[Hepatic allopurinol oxidizing enzyme in mice]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1975, Volume: 71, Issue:2 Topics: Aldehyde Oxidoreductases; Allopurinol; Animals; Chlorpromazine; Desipramine; Dexamethasone; Dialysis; Diphenhydramine; Hot Temperature; Imipramine; Ions; Liver; Male; Mice; Niacinamide; Oxypurinol; Testosterone; Time Factors; Vitamin K; Xanthine Oxidase	1975
Uptake and efflux of 14C-paraquat by rat lung slices: the effect of imipramine and other drugs. Toxicology and applied pharmacology, 1979, Volume: 49, Issue:3 Topics: Animals; Biogenic Amines; Central Nervous System Agents; Diphenhydramine; Dose-Response Relationship, Drug; Imipramine; In Vitro Techniques; Lung; Male; Paraquat; Propranolol; Rats	1979
The hyperactive child syndrome. American family physician, 1977, Volume: 15, Issue:4 Topics: Child; Dextroamphetamine; Diphenhydramine; Humans; Hyperkinesis; Imipramine; Methylphenidate; Pemoline; Promethazine; Thioridazine	1977
[Effect of neurotropin on SART stress (stress caused by alteration of rhythms in environmental temperature) in mice and rats]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1975, Volume: 71, Issue:2 Topics: Acetylcholine; Aminobutyrates; Animals; Body Weight; Chlorpromazine; Diazepam; Diphenhydramine; Duodenum; Galvanic Skin Response; Heart Rate; Imipramine; Male; Mice; Polysaccharides; Rats; Reserpine; Respiration; Stress, Physiological; Temperature	1975
[Antagonism of guanethidine action and the others blocking agents by diphenychydramine, imipramine and dextroamphetamine in illation with human hypertension (author's transl)]. Archivos de farmacologia y toxicologia, 1975, Volume: 1, Issue:3 Topics: Animals; Dextroamphetamine; Diphenhydramine; Guanethidine; Hypertension; Imipramine; Male; Rats; Stimulation, Chemical; Vas Deferens	1975
Effects of histaminergic drugs on the contractile activity of smooth muscles from imipramine-treated rats. Methods and findings in experimental and clinical pharmacology, 1990, Volume: 12, Issue:9 Topics: Animals; Diphenhydramine; Drug Interactions; Electric Stimulation; Histamine; Imipramine; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains	1990
Transport characteristics of propantheline across rat intestinal brush border membrane. The Journal of pharmacy and pharmacology, 1988, Volume: 40, Issue:3 Topics: Animals; Chlorpromazine; Diphenhydramine; Imipramine; In Vitro Techniques; Intestinal Mucosa; Male; Membrane Potentials; Microvilli; Potassium; Propantheline; Rats; Rats, Inbred Strains; Valinomycin	1988
Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice. Neuropharmacology, 1985, Volume: 24, Issue:4 Topics: Acridines; Amitriptyline; Animals; Antidepressive Agents; Depressive Disorder; Desipramine; Diphenhydramine; Disease Models, Animal; Electroshock; Ethanol; Humans; Imipramine; Male; Maprotiline; Mianserin; Mice; Motor Activity; Nialamide; Pargyline; Tranylcypromine	1985
The use of modified cellulose papers in routine toxicological analysis. 2. Antidepressives and antihistaminics. Die Pharmazie, 1973, Volume: 28, Issue:1 Topics: Antidepressive Agents; Chlorpheniramine; Chlorpromazine; Chromatography, Ion Exchange; Chromatography, Paper; Diphenhydramine; Histamine H1 Antagonists; Imipramine; Iproniazid; Isocarboxazid; Isoniazid; Meclizine; Methods; Methylcellulose; Promethazine; Toxicology; Tranylcypromine	1973
Modification of precipitated morphine withdrawal syndrome by drugs affecting cholinergic mechanisms. European journal of pharmacology, 1973, Volume: 24, Issue:3 Topics: Animals; Atropine; Autonomic Nervous System; Diphenhydramine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Imipramine; Mecamylamine; Morphine; Morphine Dependence; Naloxone; Neurotransmitter Agents; Physostigmine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Substance Withdrawal Syndrome; Synaptic Transmission; Tolazoline	1973
Psychotropic--hypnotic drug combination. Lancet (London, England), 1967, Sep-16, Volume: 2, Issue:7516 Topics: Depression; Diphenhydramine; Drug Synergism; Epistaxis; Humans; Imipramine; Mental Disorders; Methaqualone; Thioridazine; Tongue Diseases; Tongue, Fissured; Tranquilizing Agents	1967
Dopamine-induced neurogenic vasodilatation: antagonism at the vascular level. Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 204, Issue:1 Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Cordotomy; Diphenhydramine; Dogs; Dopamine; Dopamine Antagonists; Ergotamine; Hindlimb; Histamine; Imipramine; In Vitro Techniques; Muscle Tonus; Norepinephrine; Perfusion; Phentolamine; Synaptic Transmission; Vasodilator Agents	1973
Antagonism to reserpine induced depression by imipramine, related psychoactive drugs, and some autonomic agents. Psychopharmacologia, 1965, Feb-15, Volume: 7, Issue:2 Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Behavior, Animal; Cyproheptadine; Desipramine; Diphenhydramine; Hallucinogens; Histamine H1 Antagonists; Imipramine; Lysergic Acid Diethylamide; Mice; Promazine; Psychopharmacology; Reserpine; Serotonin	1965
Specificity of antihistamine drugs and involvement of the adrenergic system in histamine deaths in the guinea pig. The Journal of pharmacology and experimental therapeutics, 1966, Volume: 153, Issue:3 Topics: Adrenal Medulla; Aerosols; Amitriptyline; Animals; Chlorpheniramine; Chlorpromazine; Diphenhydramine; Drug Antagonism; Guinea Pigs; Histamine; Histamine H1 Antagonists; Imipramine; Phenothiazines; Shock, Septic; Sympatholytics; Tripelennamine	1966
The effects of some centrally acting drugs on the glucocorticoid induction of hepatic tyrosine transaminase. Life sciences, 1969, Nov-15, Volume: 8, Issue:22 Topics: Adrenalectomy; Amitriptyline; Animals; Chlorpheniramine; Chlorpromazine; Desipramine; Diphenhydramine; Enzyme Induction; Female; Fluocinolone Acetonide; Fluorometholone; Glucocorticoids; Hydrocortisone; Imipramine; Liver; Male; Prednisone; Proadifen; Promazine; Promethazine; Rats; Reserpine; Sex Factors; Triflupromazine; Tyrosine Transaminase	1969
Influence of some drugs on the accumulation of morphine in rabbit red cells in vitro. Annales medicinae experimentalis et biologiae Fenniae, 1969, Volume: 47, Issue:2 Topics: Analgesia; Animals; Cyproheptadine; Diphenhydramine; Dopamine; Drug Synergism; Erythrocytes; Hemolysis; Histamine H1 Antagonists; Imipramine; In Vitro Techniques; Indomethacin; Isotonic Solutions; Male; Morphine; Norepinephrine; Phenothiazines; Pyrrolidines; Rabbits; Serotonin	1969
[Introduction of mass psychology in animals to pharmacology. 6. Mutural relation in simultaneity convulsion and non-convulsin in E1-mice]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1970, Jul-20, Volume: 66, Issue:4 Topics: Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Caffeine; Camphor; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Diphenhydramine; Imipramine; Mice; Nikethamide; Pentylenetetrazole; Rodent Diseases; Seizures; Tranquilizing Agents	1970
Behavioural effects od d-amphetamine alone and in combination with antidepressants, antihistamines or other psychotropic drugs in young chicks. Psychopharmacologia, 1972, Volume: 23, Issue:2 Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Chickens; Chlorpheniramine; Cocaine; Desipramine; Dextroamphetamine; Diphenhydramine; Drug Antagonism; Drug Interactions; Histamine H1 Antagonists; Imipramine; Male; Nortriptyline; Promethazine	1972
Electron capture gas chromatography of tertiary amines after a demethylation reaction to secondary amines. II. Studies of different chloroformates and alternative hydrolysis procedures. Acta pharmaceutica Suecica, 1974, Volume: 11, Issue:2 Topics: Acylation; Amitriptyline; Chromatography, Gas; Diphenhydramine; Formates; Hydrocarbons, Brominated; Hydrocarbons, Chlorinated; Hydrolysis; Imipramine; Mass Spectrometry; Methadone; Methods; Methylamines; Propylamines; Time Factors	1974
Permeability changes in the blood-brain barrier induced by nortriptyline and chlorpromazine. Toxicology and applied pharmacology, 1973, Volume: 26, Issue:1 Topics: Amitriptyline; Animals; Autoradiography; Blood-Brain Barrier; Brain; Capillaries; Carbon Radioisotopes; Cell Membrane Permeability; Cerebral Cortex; Chlorpromazine; Desipramine; Diphenhydramine; Dopamine; Imipramine; In Vitro Techniques; Inulin; Male; Mannitol; Molecular Weight; Nortriptyline; Rats; Tritium	1973
Differential changes in potency of platelet-aggregation inhibitors after preincubation in platelet-rich plasma. Research communications in chemical pathology and pharmacology, 1974, Volume: 7, Issue:1 Topics: Adenosine Diphosphate; Amitriptyline; Animals; Caffeine; Chlorpromazine; Diphenhydramine; Dipyridamole; Imipramine; Papaverine; Plasma; Platelet Adhesiveness; Swine; Time Factors; Trifluoperazine	1974
[Pharmacological studies of lithium salts. 3. General pharmacological action of LiCl on the cardiovascular system and smooth muscles]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1974, Volume: 70, Issue:2 Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Cardiovascular System; Cats; Chlorpromazine; Diphenhydramine; Dogs; Electrocardiography; Female; Guinea Pigs; Heart; Hexamethonium Compounds; Histamine; Imipramine; In Vitro Techniques; Intestine, Small; Lithium; Mice; Muscle, Smooth; Nictitating Membrane; Oxytocin; Phentolamine; Propranolol; Rats; Reserpine; Respiration; Serotonin; Stomach; Uterus	1974
A comparison of antagonists of physostigmine-induced suppression of behavior. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 157, Issue:3 Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Chlorpromazine; Columbidae; Diphenhydramine; Haplorhini; Imipramine; Male; Mecamylamine; Muscles; Parasympatholytics; Physostigmine; Scopolamine; Trihexyphenidyl	1967
Effects of amantadine and of some synthetic antiparkinsonian drugs on the behavioral response to L-DOPA in mice. Physiology & behavior, 1971, Volume: 6, Issue:4 Topics: Amantadine; Amitriptyline; Animals; Antiparkinson Agents; Atropine; Behavior, Animal; Dihydroxyphenylalanine; Diphenhydramine; Drug Synergism; Imipramine; Mice; Orphenadrine; Parasympatholytics; Pargyline; Trihexyphenidyl	1971
Studies on the central effects of bulbocapnine. Psychopharmacologia, 1971, Volume: 22, Issue:3 Topics: 5-Hydroxytryptophan; Animals; Aporphines; Catalepsy; Cats; Cerebral Cortex; Dihydroxyphenylalanine; Diphenhydramine; Drug Antagonism; Drug Synergism; Electrodes, Implanted; Electroencephalography; Humans; Imipramine; Mice; Promethazine; Rabbits; Rats; Species Specificity; Time Factors; Trihexyphenidyl	1971
[A possible mechanism of disaggregation of ADP-induced aggregates by imipramin and structurally related compouds]. Thrombosis et diathesis haemorrhagica, 1969, Nov-15, Volume: 22, Issue:2 Topics: Adenine Nucleotides; Amitriptyline; Blood Platelets; Chlorpromazine; Desipramine; Diphenhydramine; Humans; Imipramine; Nortriptyline; Optical Rotatory Dispersion; Platelet Adhesiveness; Promazine; Promethazine	1969
[Introduction of mass psychology of animals to pharmacology. 2. New screening method of drugs acting on the central nervous system]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1969, Jul-20, Volume: 65, Issue:4 Topics: Aminobutyrates; Amphetamine; Animals; Anticonvulsants; Behavior, Animal; Carbamates; Chlordiazepoxide; Chlorpromazine; Diphenhydramine; Imidazoles; Imipramine; Male; Mice; Phenobarbital; Phenytoin; Reserpine; Tranquilizing Agents	1969
[Antiallergic action of psychotropic drugs as observed in passive cutaneous anaphylaxis]. Arerugi = [Allergy], 1970, Volume: 19, Issue:10 Topics: Animals; Chlordiazepoxide; Chlorpromazine; Cyproheptadine; Diphenhydramine; Imipramine; Injections, Intravenous; Passive Cutaneous Anaphylaxis; Rabbits	1970
The effect of various drug pretreatments on amine-induced phosphorylase activation and amine uptake. The Journal of pharmacology and experimental therapeutics, 1968, Volume: 162, Issue:1 Topics: Amitriptyline; Animals; Carbon Isotopes; Depression, Chemical; Desipramine; Diphenhydramine; Drug Synergism; Female; Glucosyltransferases; Heart; Imipramine; Isoproterenol; Methylphenidate; Myocardium; Norepinephrine; Promethazine; Propranolol; Rats; Stimulation, Chemical; Tranylcypromine; Triprolidine; Tritium; Tyramine	1968
The antiparkinsonian activity of monoamine oxidase inhibitors and other agents in rats and mice. Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 176, Issue:1 Topics: Animals; Dextroamphetamine; Diphenhydramine; Imipramine; Iproniazid; Isocarboxazid; Mice; Monoamine Oxidase Inhibitors; Nialamide; Nicotine; Nortropanes; Pargyline; Parkinson Disease; Parkinson Disease, Secondary; Perphenazine; Phenelzine; Physostigmine; Rats; Scopolamine; Sulfonic Acids; Tolazoline; Tremor; Tremorine; Trihexyphenidyl; Tryptamines	1968
Analgesic profile of tranquillizers in multiple screening tests in mice. Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 176, Issue:1 Topics: Acetaminophen; Aminopyrine; Analgesics; Animals; Aspirin; Chlorpromazine; Codeine; Diazepam; Diphenhydramine; Electric Stimulation; Haloperidol; Hot Temperature; Hydroxyzine; Imipramine; Isocarboxazid; Male; Meprobamate; Mice; Morphine; Perphenazine; Phenobarbital; Phenothiazines; Promazine; Promethazine; Reserpine; Tetrabenazine; Thiopental; Time Factors; Tranquilizing Agents	1968
Clinical significance of anticholinergic effects of imipramine-like drugs. The American journal of psychiatry, 1969, Volume: 125, Issue:11 Topics: Amitriptyline; Animals; Atropine; Columbidae; Depression; Desipramine; Diphenhydramine; Humans; Imipramine; Parasympatholytics; Scopolamine	1969
Inhibition of serotonin-induced platelet aggregation in relation to thrombus production. The Journal of pharmacology and experimental therapeutics, 1969, Volume: 166, Issue:2 Topics: Adenine Nucleotides; Animals; Atropa belladonna; Atropine; Blood Coagulation; Blood Platelets; Chlorpromazine; Densitometry; Diphenhydramine; Fibrin; Imipramine; In Vitro Techniques; Lysergic Acid Diethylamide; Methods; Plants, Medicinal; Plants, Toxic; Plasma; Serotonin Antagonists; Sheep; Thrombin; Thrombosis	1969
Loss of teeth with antidepressant drug therapy. Archives of general psychiatry, 1967, Volume: 16, Issue:2 Topics: Dental Caries; Diphenhydramine; Humans; Imipramine; Male; Middle Aged; Parkinson Disease; Psychopharmacology; Trihexyphenidyl; Xerostomia	1967
Imipramine inhibition of transient K+ current: an external open channel blocker preventing fast inactivation. Biophysical journal, 1998, Volume: 75, Issue:6 Topics: Animals; Antidepressive Agents, Tricyclic; Benztropine; Binding Sites; Biophysical Phenomena; Biophysics; Diphenhydramine; Hippocampus; Hydrogen-Ion Concentration; Imipramine; In Vitro Techniques; Ion Channel Gating; Kinetics; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Protein Conformation; Rats	1998
Inhibition of Na(+) current by imipramine and related compounds: different binding kinetics as an inactivation stabilizer and as an open channel blocker. Molecular pharmacology, 2002, Volume: 62, Issue:5 Topics: Adrenergic Uptake Inhibitors; Amino Acid Motifs; Animals; Binding Sites; Carbamazepine; Diphenhydramine; Dose-Response Relationship, Drug; Imipramine; Kinetics; Membrane Potentials; Mutation; Protein Conformation; Rats; Rats, Long-Evans; Sodium Channel Blockers; Sodium Channels	2002
ANTAGONISTIS OF BRADYKININ. Medicina experimentalis : International journal of experimental medicine, 1963, Volume: 8 Topics: Animals; Atropine; Bradykinin; Cyproheptadine; Diphenhydramine; Guanethidine; Guinea Pigs; Ileum; Imipramine; Phenothiazines; Phenoxybenzamine; Research; Sympatholytics; Thioridazine	1963
DIPHENHYDRAMINE AS AN ANTIDEPRESSANT: A NEGATIVE FINDING. Diseases of the nervous system, 1964, Volume: 25 Topics: Antidepressive Agents; Biomedical Research; Bipolar Disorder; Depressive Disorder, Major; Diphenhydramine; Drug Therapy; Imipramine; Isocarboxazid; Placebos; Psychotic Disorders; Schizophrenia; Toxicology	1964
Human UDP-glucuronosyltransferase (UGT) 2B10 in drug N-glucuronidation: substrate screening and comparison with UGT1A3 and UGT1A4. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:7 Topics: Amitriptyline; Animals; Diphenhydramine; Glucuronides; Glucuronosyltransferase; Humans; Imipramine; Kinetics; Spodoptera; Substrate Specificity	2013
Unusual stacking with electrokinetic injection of cationic analytes from micellar solutions in capillary zone electrophoresis. Analytical and bioanalytical chemistry, 2016, Volume: 408, Issue:30 Topics: Acetonitriles; Cations; Diphenhydramine; Electrophoresis, Capillary; Flow Injection Analysis; Imipramine; Kinetics; Micelles; Sodium Dodecyl Sulfate; Solutions; Static Electricity	2016
How do psychostimulants enter the human brain? Analysis of the role of the proton-organic cation antiporter. Biochemical pharmacology, 2021, Volume: 192 Topics: Antiporters; Blood-Brain Barrier; Brain; Cells, Cultured; Central Nervous System Stimulants; Diphenhydramine; Dose-Response Relationship, Drug; Humans; Imipramine; Organic Cation Transport Proteins; Proton Pumps	2021