imipramine and didesipramine

imipramine has been researched along with didesipramine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's8 (53.33)18.2507
2000's3 (20.00)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glennon, RA; Roth, BL; Runyon, SP; Savage, JE; Taroua, M; Westkaemper, RB1
Bures, P; Fuksová, K; Krulík, R; Sikora, J1
Bures, P; Havránek, M; Krulík, R; Simůnková, D1
Borsini, F; D'Aranno, V; Lecci, A; Mancinelli, A; Meli, A; Stasi, MA1
Beckett, AH; Hutt, AJ; Navas, GE1
Barkai, AI; Cooper, TB; Suckow, RF1
Bjerre, M; Gram, LF; Kragh-Sørensen, P; Kvinesdal, B; Molin, J; Pedersen, OL; Reisby, N1
Argenti, D; D'Mello, AP2
Bensoussan, C; Delaforge, M; Mansuy, D1
Sequeira, DJ; Strobel, HW1
Kelly, JP; Leonard, BE1
Burke, WJ; Bylund, DB; Deupree, JD; Kozisek, ME1
Bylund, DB; Deupree, JD; Montgomery, MD1
Allen, KE; Babu, KN; Hanson, KL; Kunze, KL; Nelson, WL; VandenBrink, BM1

Other Studies

15 other study(ies) available for imipramine and didesipramine

ArticleYear
Influence of chain length and N-alkylation on the selective serotonin receptor ligand 9-(aminomethyl)-9,10-dihydroanthracene.
    Bioorganic & medicinal chemistry letters, 2001, Mar-12, Volume: 11, Issue:5

    Topics: Animals; Anthracenes; Cell Line; Ligands; Molecular Conformation; Molecular Structure; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists

2001
Methylated and demethylated tricyclic antidepressants and their binding to cell membranes.
    Drug metabolism and drug interactions, 1991, Volume: 9, Issue:3-4

    Topics: Animals; Antidepressive Agents, Tricyclic; Blood Platelets; Cattle; Cell Membrane; Dealkylation; Desipramine; Erythrocyte Membrane; Imipramine; In Vitro Techniques; Lymphocytes; Methylation; Phosphatidylserines; Phospholipids; Synaptic Membranes

1991
Changes of ligand binding after membrane phosphorylation.
    Drug metabolism and drug interactions, 1991, Volume: 9, Issue:3-4

    Topics: Animals; Antidepressive Agents, Tricyclic; Cattle; Dealkylation; Desipramine; Dibenzazepines; Humans; Imipramine; In Vitro Techniques; Kinetics; Ligands; Phosphorylation; Synaptic Membranes

1991
Effect of enantiomers of propranolol on desipramine-induced anti-immobility in the forced swimming test in the rat.
    Pharmacological research, 1991, Volume: 23, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Desipramine; Imipramine; Male; Propranolol; Rats; Rats, Inbred Strains; Stereoisomerism; Swimming

1991
Metabolism of imipramine in vitro: synthesis and characterization of N-hydroxydesmethylimipramine.
    Xenobiotica; the fate of foreign compounds in biological systems, 1983, Volume: 13, Issue:7

    Topics: Animals; Chemical Phenomena; Chemistry; Desipramine; Gas Chromatography-Mass Spectrometry; Imipramine; Magnetic Resonance Spectroscopy; Male; Microsomes, Liver; Rabbits

1983
Imipramine and its metabolites: relationship to cerebral catecholamines in rats in vivo.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:2

    Topics: Animals; Brain; Desipramine; Dopamine; Imipramine; Injections, Intraventricular; Kinetics; Male; Norepinephrine; Rats; Rats, Inbred Strains; Time Factors; Tissue Distribution

1984
Imipramine metabolites in blood of patients during therapy and after overdose.
    Clinical pharmacology and therapeutics, 1983, Volume: 33, Issue:3

    Topics: Adult; Aged; Chromatography, Thin Layer; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Kinetics; Male; Middle Aged

1983
Design of a desipramine dosing regimen for the rapid induction and maintenance of maximal cortical beta-adrenoceptor downregulation.
    Neuropharmacology, 1994, Volume: 33, Issue:9

    Topics: Animals; Brain; Cerebral Cortex; Desipramine; Down-Regulation; Imipramine; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta

1994
Particular ability of cytochromes P450 3A to form inhibitory P450-iron-metabolite complexes upon metabolic oxidation of aminodrugs.
    Biochemical pharmacology, 1995, Mar-01, Volume: 49, Issue:5

    Topics: Amines; Animals; Biotransformation; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Imipramine; Iron; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Spectrophotometry

1995
The pharmacodynamics of desipramine and desmethyldesipramine in rats.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Binding Sites; Desipramine; Dose-Response Relationship, Drug; Down-Regulation; Imipramine; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta

1994
High-performance liquid chromatographic method for the analysis of imipramine metabolism in vitro by liver and brain microsomes.
    Journal of chromatography. B, Biomedical applications, 1995, Nov-17, Volume: 673, Issue:2

    Topics: Animals; Brain; Chromatography, High Pressure Liquid; Desipramine; Hydroxylation; Imipramine; Male; Microsomes; Microsomes, Liver; Rats; Rats, Sprague-Dawley

1995
An investigation of the antidepressant properties of lofepramine and its desmethylated metabolites in the forced swim and olfactory bulbectomized rat models of depression.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 9, Issue:1-2

    Topics: Animals; Antidepressive Agents, Tricyclic; Depression; Desipramine; Dose-Response Relationship, Drug; Imipramine; Lofepramine; Male; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Swimming

1999
Appropriate dosing regimens for treating juvenile rats with desipramine for neuropharmacological and behavioral studies.
    Journal of neuroscience methods, 2007, Jun-15, Volume: 163, Issue:1

    Topics: Age Factors; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Desipramine; Dose-Response Relationship, Drug; Drug Administration Schedule; Half-Life; Imipramine; Male; Protein Binding; Rats; Rats, Sprague-Dawley; Swimming; Time Factors

2007
Pharmacological properties of the active metabolites of the antidepressants desipramine and citalopram.
    European journal of pharmacology, 2007, Dec-08, Volume: 576, Issue:1-3

    Topics: Animals; Antidepressive Agents; Citalopram; Desipramine; Imipramine; Male; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Serotonin Plasma Membrane Transport Proteins

2007
Sequential metabolism of secondary alkyl amines to metabolic-intermediate complexes: opposing roles for the secondary hydroxylamine and primary amine metabolites of desipramine, (s)-fluoxetine, and N-desmethyldiltiazem.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:6

    Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Desipramine; Diltiazem; Fluoxetine; Humans; Hydroxylamine; Hydroxylamines; Hydroxylation; Imipramine; Microsomes, Liver; Oxidoreductases, N-Demethylating; Steroid 16-alpha-Hydroxylase

2010