imipramine has been researched along with corticosterone in 129 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (14.73) | 18.7374 |
| 1990's | 18 (13.95) | 18.2507 |
| 2000's | 39 (30.23) | 29.6817 |
| 2010's | 51 (39.53) | 24.3611 |
| 2020's | 2 (1.55) | 2.80 |
| Authors | Studies |
|---|---|
| Gubernator, K; Kansy, M; Senner, F | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Caron, G; Ermondi, G | 1 |
| Carrupt, PA; Martel, S; Ottaviani, G | 1 |
| Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Andrisano, V; Barril, X; Bartolini, M; Carreiras, Mdo C; de los Ríos, C; García, AG; Huertas, O; León, R; López, B; López, MG; Luque, FJ; Marco-Contelles, J; Rodríguez-Franco, MI; Samadi, A; Villarroya, M | 1 |
| Andrisano, V; Arce, MP; Badia, A; Bartolini, M; Camps, P; Clos, MV; Dafni, T; Formosa, X; Galdeano, C; Gómez, E; Huertas, O; Isambert, N; Lavilla, R; Luque, FJ; Mancini, F; Muñoz-Torrero, D; Ramírez, L; Rodríguez-Franco, MI | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Arce, MP; Conde, S; García, AG; González-Muñoz, GC; López, B; López, MG; Pérez, C; Rodríguez-Franco, MI; Villarroya, M | 1 |
| Akamatsu, M | 1 |
| Arce, MP; Conde, S; del Barrio, L; Egea, J; García, AG; González-Muñoz, GC; León, R; López, B; López, MG; Martín-de-Saavedra, MD; Pérez, C; Rodríguez-Franco, MI; Romero, A; Villarroya, M | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
| Andrisano, V; Bartolini, M; Clos, MV; Di Pietro, O; Juárez-Jiménez, J; Lavilla, R; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Ramón, R; Viayna, E; Vicente-García, E | 1 |
| Clos, MV; Di Pietro, O; Espargaró, A; Juárez-Jiménez, J; Lavilla, R; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Sabaté, R | 1 |
| Clos, MV; Di Pietro, O; Espargaró, A; Galdeano, C; Guillou, C; Lamuela-Raventós, RM; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Ragusa, IM; Sabaté, R; Vallverdú-Queralt, A; Viayna, E | 1 |
| Artigas, A; Clos, MV; Gbedema, SY; Kelly, JM; Muñoz-Torrero, D; Pérez, B; Sola, I; Taylor, MC; Wright, CW | 1 |
| Berenguer, D; Clos, MV; Di Pietro, O; Fisa, R; Kelly, JM; Lanzoni, A; Lavilla, R; Muñoz-Torrero, D; Pérez, B; Riera, C; Sayago, H; Sola, I; Taylor, MC; Viayna, E; Vicente-García, E | 1 |
| Alencar, N; Di Pietro, O; Esteban, G; Juárez-Jiménez, J; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Sola, I; Solé, M; Szałaj, N; Unzeta, M; Vázquez, J; Viayna, E | 1 |
| Artigas, A; Clos, MV; Kelly, JM; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Sola, I; Taylor, MC; Viayna, E; Wright, CW | 1 |
| Arce, MP; Conde, S; Egea, J; Gil, C; León, R; López, MG; Monjas, L; Pérez, C; Rodríguez-Franco, MI; Villarroya, M | 1 |
| Huang, Q; Jiang, N; Li, Q; Liang, N; Liu, J; Xie, SS | 1 |
| Alcaro, S; Bagetta, D; Borges, F; Cagide, F; Oliveira, PJ; Ortuso, F; Pérez, C; Reis, J; Rodríguez-Franco, MI; Teixeira, J; Uriarte, E; Valencia, ME | 1 |
| Andrisano, V; Barniol-Xicota, M; Bartolini, M; De Simone, A; Espargaró, A; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Pivetta, D; Pont, C; Sabate, R; Sureda, FX; Turcu, AL; Vázquez, S | 1 |
| Brea, JM; Companys-Alemany, J; Griñán-Ferré, C; Johnson, JW; Kurnikova, MG; Loza, MI; Pallàs, M; Patel, DS; Pérez, B; Phillips, MB; Soto, D; Sureda, FX; Turcu, AL; Vázquez, S | 1 |
| Grota, LJ | 1 |
| Day, TA; Overstreet, DH; Schiller, GD | 1 |
| Bobkiewicz, T; Chodera, A; Nowakowska, E; Okulicz-Kozaryn, I | 1 |
| Gálfi, M; Julesz, J; Molnár, J; Vecsernyés, M | 1 |
| Brady, LS; Fox, RJ; Gold, PW; Herkenham, M; Whitfield, HJ | 1 |
| D'Aponte, D; De Franciscis, P; Gambardella, P; Greco, AM; Sticchi, R | 1 |
| Aulakh, CS; Haass, M; Hill, JL; Murphy, DL; Wozniak, KM; Zohar, J | 2 |
| Breese, GR; Duncan, GE; Hong, JS; Kuhn, C; Mueller, RA; Paul, IA | 1 |
| Abel, EL; Bilitzke, P | 1 |
| Rotsch, M; Schulz, E; Wesemann, W; Zöfel, P | 1 |
| Ohi, K; Shimoda, K; Takahashi, K; Takahashi, S; Tsujimoto, T; Yamada, N | 1 |
| Aulakh, CS; Hill, JL; Murphy, DL; Wozniak, KM | 1 |
| Fukuda, S; Lee, TJ; Su, C | 1 |
| Agnati, LF; Cintra, A; Eneroth, P; Fuxe, K; Gustafsson, JA; Härfstrand, A; Janson, AM; Kitayama, I; Ogren, SO | 1 |
| D'Aponte, D; de Franciscis, P; Gambardella, P; Greco, AM; Santangelo, F; Sticchi, R | 1 |
| Arora, RC; Meltzer, HY | 1 |
| Hauser, K; Häusler, A; Meeker, JB | 1 |
| Chan, MY; Lee, PH | 1 |
| Free, CA; Paik, VS; Shada, JD | 1 |
| Boergen, KP; Lund, OE | 1 |
| Di Salle, E; Jori, A; Santini, V | 1 |
| Agnati, LF; Andersson, K; Benfenati, F; Eneroth, P; Fredholm, B; Fuxe, K; Ogren, SO; Zini, I | 1 |
| Katz, RJ; Roth, KA | 1 |
| Gubbels, DG; Peeters, BW; van der Heijden, R; Vanderheyden, PM | 1 |
| Labow, DM; Tejani-Butt, SM | 1 |
| Budziszewska, B; Przegaliński, E | 1 |
| Agnati, LF; Biagini, G; Carani, C; Fuxe, K; Gustafsson, JA; Marrama, P; Pich, EM | 1 |
| McEwen, BS; Mendelson, S; Sakai, RR; Watanabe, Y | 1 |
| Aulakh, CS; Hill, JL; Murphy, DL | 1 |
| Breese, GR; Carson, SW; Duncan, GE; Knapp, DJ | 1 |
| Arushanian, EB; Beĭer, EV; El'bek'ian, KS | 1 |
| Armario, A; Gómez, F; Graugés, P; Martín, M | 1 |
| Arregi, A; Azpiroz, A; Beitia, G; Brain, PF; Cacho, R; Fano, E; Garmendia, L | 1 |
| Budziszewska, B; Jaworska-Feil, L; Kajta, M; Lasoń, W | 1 |
| Avitsur, R; Barak, O; Bette, M; Ovadia, H; Pollak, Y; Weidenfeld, J; Weihe, E; Yirmiya, R | 1 |
| Bijak, M; Tokarski, K; Zahorodna, A | 1 |
| Butterweck, V; Korte, B; Winterhoff, H | 1 |
| Butterweck, V; Herkenham, M; Winterhoff, H | 1 |
| Breivik, T; Pabst, R; Stephan, M; Straub, RH; von Hörsten, S | 1 |
| Connor, TJ; Dredge, K; Kelly, JP; Leonard, BE | 1 |
| GELLER, E; SCHAPIRO, S; SLATER, GG; YUWILER, A | 1 |
| Bornstein, S; Ehrhart-Bornstein, M; Frost, P; Go, V; Heber, D; Hutson, C; Licinio, J; O'Kirwan, F; Wong, ML | 1 |
| Gur, E; Lerer, B; Lifschytz, T; Newman, ME; Van De Kar, LD | 1 |
| Abe, K; Itoh, T; Tokumura, M | 1 |
| Basta-Kaim, A; Budziszewska, B; Jaworska-Feil, L; Kubera, M; Lasoń, W; Rogóz, Z; Skuza, G | 1 |
| Basta-Kaim, A; Budziszewska, B; Jaworska-Feil, L; Kubera, M; Lason, W; Leskiewicz, M; Maes, M; Rogóz, Z; Skuza, G; Tetich, M | 1 |
| Hess, G; Tokarski, K; Zahorodna, A | 1 |
| Che, W; Matsumoto, K; Min-Wei, W; Murakami, Y; Song, L | 1 |
| Hess, G; Zahorodna, A | 1 |
| Acevedo, EO; Cartwright, CM; Feltenstein, MW; Sufka, KJ; Warnick, JE; Webb, HE | 1 |
| Akiyama, K; Araki, H; Gomita, Y; Hashimoto, S; Kawasaki, H; Kitagawa, K; Kitamura, Y; Sendo, T; Shibata, K; Shinomiya, K; Suemaru, K | 1 |
| Cassanelli, A; Danielli, B; De Montis, MG; Raone, A; Rauggi, R; Scheggi, S | 1 |
| Higashi, M; Hitoshi, S; Ikenaka, K; Kato, N; Kumar, A; Maruta, N | 1 |
| Becker, C; Benoliel, JJ; Blugeot, A; Hamon, M; Rivat, C; Zeau, B | 1 |
| Hutson, PH; Murray, F; Smith, DW | 1 |
| Costentin, J; do Rego, JC; Janin, F; Naudin, B; Rates, S; Viana, A | 1 |
| Caumo, W; Detanico, BC; Elisabetsky, E; Freitas, JJ; Hidalgo, MP; Lhullier, FL; Piato, AL | 1 |
| Andres, CR; Belzung, C; Gardier, AM; Ibarguen-Vargas, Y; Leman, S; Surget, A; Vourc'h, P | 1 |
| Barish, PA; Li, G; Li, S; Lin, D; Ogle, WO; Pan, J; Shyamala, SG; Vernon, MM; Xu, Y | 1 |
| Heydendael, W; Jacobson, L | 1 |
| Duszynska, B; Hess, G; Pitra, P; Tokarski, K | 1 |
| Barichello, T; Cassol, OJ; Comim, CM; Constantino, LC; Constantino, LS; Dal-Pizzol, F; Kapczinski, F; Petronilho, F; Quevedo, J; Stertz, L | 1 |
| Alekhina, TA; Klotchkov, DV; Kuznetsova, NV; Palchikova, NA; Rjazanova, MA; Ukolova, TN | 1 |
| Andersen, ML; Andreatini, R; Araujo, P; Correia, D; Lima, MM; Louzada, FM; Martynhak, BJ; Morais, LH | 1 |
| Hoogendijk, WJ; Lucassen, PJ; Oomen, CA; Smit, AB; Spijker, S; Van Bokhoven, P | 1 |
| Domokos, Á; Mergl, Z; Mikics, É; Pintér, O; Zelena, D | 1 |
| Becker, C; Benoliel, JJ; Bernard, C; Blugeot, A; Bouvier, E; Molet, J; Mouchard, A; Rivat, C; Zeau, B | 1 |
| de Castro, GM; Diniz, L; Dos Reis, BB; Medalha, CC; Viana, MB | 1 |
| Barichello, T; Cipriano, AL; Comim, CM; Costa, CS; Generoso, JS; Milioli, G; Moreira, AP; Quevedo, J; Teixeira, AL; Vilela, MC | 1 |
| Bobula, B; Hess, G; Wabno, J | 1 |
| Beck, SG; Berton, O; Boulden, J; Challis, C; Chan, M; Deneris, E; Espallergues, J; Hahn, CG; Jochems, J; Lucki, I; Matthias, P; Petersen, T; Teegarden, SL; Veerakumar, A | 1 |
| Choi, J; Han, PL; Kim, TK; Lee, JK; Park, JY; Seo, JS; Shin, JH | 1 |
| Britto, LR; Céspedes, IC; de Castro, GM; Diniz, L; dos Santos, TB; Garcia, MC; Medalha, CC; Montesano, FT; Spadari-Bratfisch, RC; Viana, MB | 1 |
| Berk, M; Burnett, SA; Gray, LJ; Hasebe, K; McGee, SL; McGillivray, JA; Tye, SJ; Walder, K; Walker, AJ | 1 |
| Huang, Z; Mao, QQ; Qiu, FM; Zhong, XM | 1 |
| Cui, R; Li, B; Liu, L; Lv, J; Manchishi, SM; Siwela, SP; Song, Y; Sun, Z; Tang, F; Wang, L; Wang, Y; Zhao, J | 1 |
| Ardayfio, PA; Han, BS; Han, PL; Jung, BH; Kang, Y; Kang, YM; Kim, CH; Kim, KS; Kim, YJ; Lee, CH; Park, HY; Park, TS | 1 |
| Flak, JN; Herman, JP; McKlveen, J; Myers, B; Rice, T; Solomon, MB; Ulrich-Lai, Y; Wick, D; Wulsin, AC | 1 |
| Chen, L; Guan, XT; Shao, F; Wang, W; Xie, X | 1 |
| Abd-Alkhalek, HA; Abdel-tawab, AM; Aboul-Fotouh, S; El Tabbal, M; Elgarf, AS; Farrag, KA; Hammouda, GA; Hassan, AN; Kassim, SK | 1 |
| Benvenutti, R; Elisabetsky, E; Hidalgo, MP; Levandovski, R; Melo, G; Pilz, LK; Quiles, CL; Trojan, Y | 1 |
| Hussain, RJ; Jacobson, L | 1 |
| Caruncho, HJ; Fenton, EY; Fournier, NM; Kalynchuk, LE; Lussier, AL; Romay-Tallon, R | 1 |
| Buendia, I; Casas, AI; Cuadrado, A; Egea, J; Freitas, AE; Gómez-Rangel, V; Lopez, MG; Navarro, E; Ortiz, JA; Parada, E; Rodrigues, ALS; Ruiz-Nuño, A; Wojnicz, A | 1 |
| Alekhina, TA; Igonina, TN; Kuznetsova, NV; Palchikova, NA | 1 |
| Bansal, S; Dhingra, D | 1 |
| Ji, L; Li, H; Liu, W; Wang, Y | 1 |
| Chow, C; Galea, LA; Hamson, DK; Lieblich, SE; Tehrani, A; Wainwright, SR; Workman, JL | 1 |
| Ding, Q; Huang, J; Li, H; Mo, F; Shen, H; Shen, Z; Tian, X; Wang, X | 1 |
| Poleszak, E; Rechberger, T; Serefko, A; Wróbel, A | 1 |
| Ramirez, K; Sheridan, JF | 1 |
| Barichello, T; Dominguini, D; Generoso, JS; Jornada, LK; Quevedo, J; Sharin, VS; Simões, LR; Souza, LB; Teixeira, AL; Valvassori, SS | 1 |
| Berman, S; Caldwell, JL; Estrada, CM; Ghisays, V; Nguyen, ET; Solomon, MB; Streicher, J; Wulsin, AC | 1 |
| Adebesin, A; Adeoluwa, OA; Eduviere, AT; Umukoro, S | 1 |
| Balmer, NJ; Caldwell, JL; Estrada, CM; Ghisays, V; Nguyen, ET; Solomon, MB; Streicher, J | 1 |
| Adebesin, A; Ajayi, AM; Olonode, EO; Omorogbe, O; Umukoro, S | 1 |
| Elfving, B; Harvey, BH; Joca, SRL; Pereira, VS; Wegener, G | 1 |
| Bobinski, F; Cassol, OJ; Comim, CM; Dias, P; Dutra, ML; Freiberger, V; Schelder-Marzzani, SH; Schlindwein, AD; Silva, BB; Ventura, L | 1 |
| Arikawe, AP; Costa, EA; Costa, RF; Fajemiroye, JO; Moreira, CVL; Napolitano, HB; Oliveira-Silva, I; Pedrino, GR; Prado, CC; Rodrigues, ACC; Silva, LSB; Silva, ON | 1 |
2 review(s) available for imipramine and corticosterone
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
Chronic antidepressant treatment and central 5-HT synapses.
Topics: Animals; Antidepressive Agents; Carrier Proteins; Corticosterone; Cyclic AMP; Dihydroalprenolol; Hippocampus; Humans; Imipramine; Lysergic Acid Diethylamide; Pituitary Hormones, Anterior; Receptors, Drug; Receptors, Neurotransmitter; Receptors, Serotonin; Serotonin; Spiperone; Substance P | 1983 |
127 other study(ies) available for imipramine and corticosterone
| Article | Year |
|---|---|
Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes.
Topics: Absorption; Adsorption; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Permeability; Pharmacokinetics; Spectrophotometry, Ultraviolet | 1998 |
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water | 2007 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Butyrylcholinesterase; Calcium; Calcium Channel Blockers; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytosol; Dihydropyridines; Humans; Hydrogen Peroxide; Kinetics; Ligands; Models, Molecular; Peptide Fragments; Permeability; Tacrine | 2009 |
Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Drug Design; Humans; Isomerism; Membranes, Artificial; Mice; Models, Molecular; Molecular Conformation; Permeability; Protein Binding; Tacrine | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Catalytic Domain; Cattle; Cell Death; Cell Line, Tumor; Cell Survival; Cholinergic Agents; Cholinesterase Inhibitors; Esters; Glutamic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Neuroprotective Agents; Permeability; Piperidines; Protein Binding | 2009 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Agents; Butyrylcholinesterase; Calcium; Cell Death; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Okadaic Acid; Peptide Fragments; Phenothiazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
1,2,3,4-Tetrahydrobenzo[h][1,6]naphthyridines as a new family of potent peripheral-to-midgorge-site inhibitors of acetylcholinesterase: synthesis, pharmacological evaluation and mechanistic studies.
Topics: Acetylcholinesterase; Animals; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Electrophorus; Humans; Membranes, Artificial; Models, Biological; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Naphthyridines; Permeability; Protein Binding | 2014 |
Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Cholinesterase Inhibitors; Cholinesterases; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Naphthyridines; Structure-Activity Relationship; Tacrine; tau Proteins; Tauopathies | 2014 |
Shogaol-huprine hybrids: dual antioxidant and anticholinesterase agents with β-amyloid and tau anti-aggregating properties.
Topics: Acetylcholinesterase; Aminoquinolines; Amyloid beta-Peptides; Antioxidants; Catechols; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Heterocyclic Compounds, 4 or More Rings; Humans; Molecular Structure; Protein Aggregates; Protein Aggregation, Pathological; Structure-Activity Relationship; tau Proteins | 2014 |
Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprines.
Topics: Antimalarials; Antiprotozoal Agents; Humans; Molecular Structure; Structure-Activity Relationship | 2014 |
Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity.
Topics: Acetylcholinesterase; Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electrophorus; Leishmania infantum; Molecular Structure; Parasitic Sensitivity Tests; Quinolines; Rats; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosoma cruzi | 2015 |
Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors.
Topics: Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Structure-Activity Relationship | 2016 |
Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents.
Topics: Aminoquinolines; Brain; Dose-Response Relationship, Drug; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei | 2016 |
Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.
Topics: Alzheimer Disease; Animals; Brain Ischemia; Calcium Channel Blockers; Cholinesterase Inhibitors; Donepezil; Glutamates; Hippocampus; Humans; Indans; Neuroprotective Agents; Piperidines; Rats; Solid-Phase Synthesis Techniques | 2017 |
Design, synthesis and biological evaluation of new coumarin-dithiocarbamate hybrids as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cell Line, Tumor; Cholinesterase Inhibitors; Coumarins; Dose-Response Relationship, Drug; Drug Design; Humans; Kinetics; Male; Mice; Mice, Inbred Strains; Models, Molecular; Molecular Structure; Peptide Fragments; Protein Aggregates; Range of Motion, Articular; Structure-Activity Relationship; Thiocarbamates | 2018 |
Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors.
Topics: Alzheimer Disease; Blood-Brain Barrier; Cholinesterase Inhibitors; Cholinesterases; Chromones; Drug Design; Hep G2 Cells; Humans; Ligands; Molecular Docking Simulation; Molecular Targeted Therapy; Monoamine Oxidase; Monoamine Oxidase Inhibitors | 2018 |
A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors.
Topics: Acetylcholinesterase; Adamantane; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Neuroprotective Agents; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Tacrine | 2019 |
Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Disease Models, Animal; Memantine; Mice; Receptors, N-Methyl-D-Aspartate | 2022 |
Plasma corticosterone response to serotonin altering drugs in the 3-day-old rat.
Topics: 5-Hydroxytryptophan; Adrenal Cortex; Animals; Animals, Newborn; Corticosterone; Cyproheptadine; Imipramine; Neurotransmitter Agents; Rats; Serotonin | 1979 |
Centrally administered cycloheximide in rats: behavioural concomitants and modulation of amnesic effects by biogenic amines.
Topics: Amnesia; Animals; Behavior, Animal; Biogenic Amines; Brain; Conditioning, Operant; Corticosterone; Cycloheximide; Dextroamphetamine; Escape Reaction; Humans; Hydrocortisone; Imipramine; Injections, Intraventricular; Male; Memory; Motor Activity; Nerve Tissue Proteins; Protein Biosynthesis; Rats; Retention, Psychology; Time Factors; Tryptophan | 1977 |
Influence of tricyclic antidepressant drugs on experimental arterial hypertension.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Female; Hexobarbital; Hypertension; Imipramine; Kidney; Male; Nephrectomy; Nortriptyline; Opipramol; Rats | 1975 |
Central effects of tricyclic compounds on the endocrine system--an in vitro study.
Topics: Adrenocorticotropic Hormone; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cells, Cultured; Chlorpromazine; Corticosterone; Cyclic AMP; Drug Interactions; Haloperidol; Imipramine; Lypressin; Pituitary Gland; Promethazine; Rats; Rats, Wistar | 1992 |
Long-term antidepressant administration alters corticotropin-releasing hormone, tyrosine hydroxylase, and mineralocorticoid receptor gene expression in rat brain. Therapeutic implications.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Body Weight; Corticosterone; Corticotropin-Releasing Hormone; Gene Expression; Imipramine; Locus Coeruleus; Nucleic Acid Hybridization; Organ Size; Paraventricular Hypothalamic Nucleus; Pituitary Gland, Anterior; Pro-Opiomelanocortin; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Receptors, Steroid; RNA, Messenger; Secretory Rate; Time Factors; Tyrosine 3-Monooxygenase | 1991 |
Chronic administration of imipramine antagonizes deranged circadian rhythm phases in individually housed rats.
Topics: Animals; Circadian Rhythm; Corticosterone; Hydroxyindoleacetic Acid; Hypothalamus; Imipramine; Male; Rats; Rats, Inbred Strains; Serotonin; Social Environment; Social Isolation; Tryptophan | 1990 |
Differential effects of antidepressant treatments on fenfluramine-induced increases in plasma prolactin and corticosterone in rats.
Topics: Animals; Antidepressive Agents; Clorgyline; Corticosterone; Drug Interactions; Fenfluramine; Imipramine; Injections, Intravenous; Lithium; Male; Prolactin; Rats; Rats, Inbred Strains | 1991 |
Neural adaptation in imipramine-treated rats processed in forced swim test: assessment of time course, handling, rat strain and amine uptake.
Topics: Adaptation, Physiological; Animals; Behavior, Animal; Cerebral Cortex; Corticosterone; Dihydroalprenolol; Fluoxetine; Hippocampus; Imipramine; Ketanserin; Male; Physical Exertion; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, GABA-A; Species Specificity; Swimming | 1990 |
Paternal alcohol exposure: paradoxical effect in mice and rats.
Topics: Animals; Behavior, Animal; Corticosterone; Ethanol; Female; Imipramine; Male; Metergoline; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Propranolol; Rats; Sex Factors; Social Isolation; Species Specificity; Swimming; Yohimbine | 1990 |
Long-term imipramine treatment potentiates m-chlorophenylpiperazine-induced changes in prolactin but not corticosterone or growth hormone levels in rats.
Topics: Animals; Corticosterone; Drug Synergism; Growth Hormone; Imipramine; Male; Piperazines; Prolactin; Rats; Rats, Inbred Strains; Time Factors | 1989 |
Circadian rhythm of serotonin binding in rat brain--II. Influence of sleep deprivation and imipramine.
Topics: Adrenocorticotropic Hormone; Animals; Brain; Circadian Rhythm; Corticosterone; Imipramine; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Sleep Deprivation | 1986 |
Chronic administration of tricyclic antidepressants suppresses hypothalamo-pituitary-adrenocortical activity in male rats.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Corticosterone; Desipramine; Dexamethasone; Dose-Response Relationship, Drug; Hypothalamo-Hypophyseal System; Imipramine; Male; Pituitary-Adrenal System; Rats; Rats, Inbred Strains | 1988 |
Differential effects of long-term antidepressant treatments on 8-OHDPAT-induced increases in plasma prolactin and corticosterone in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Clomipramine; Clorgyline; Corticosterone; Imipramine; Male; Naphthalenes; Prolactin; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes; Time Factors | 1988 |
Mechanisms of extraneuronal serotonin uptake in the rat aorta.
Topics: Animals; Aorta; Cocaine; Cold Temperature; Corticosterone; Desipramine; Hydroxydopamines; Imipramine; Kinetics; Male; Neurons; Norepinephrine; Oxidopamine; Pargyline; Rats; Rats, Inbred Strains; Serotonin | 1986 |
Effects of chronic imipramine treatment on glucocorticoid receptor immunoreactivity in various regions of the rat brain. Evidence for selective increases of glucocorticoid receptor immunoreactivity in the locus coeruleus and in 5-hydroxytryptamine nerve c
Topics: Aldosterone; Animals; Brain; Corticosterone; Histocytochemistry; Imipramine; Locus Coeruleus; Male; Medulla Oblongata; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Reference Values; Serotonin | 1988 |
[Circadian rhythm of serum corticosterone in rats treated with imipramine].
Topics: Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Corticosterone; Imipramine; Male; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Effect of adrenalectomy and corticosterone on [3H]imipramine binding in rat blood platelets and brain.
Topics: Adrenalectomy; Animals; Blood Platelets; Brain; Corticosterone; Imipramine; In Vitro Techniques; Kinetics; Male; Rats; Rats, Inbred Strains | 1986 |
Effects of subchronic administration of psychoactive substances on the circadian rhythm of urinary corticosterone excretion in rats.
Topics: Animals; Antidepressive Agents; Circadian Rhythm; Clorgyline; Corticosterone; Fluoxetine; Imipramine; Male; Maprotiline; Pargyline; Propylamines; Rats; Trimipramine | 1985 |
Changes induced by corticosterone and adrenalectomy in synaptosomal and platelet uptake and binding of 5-HT. The relationship to [3H]imipramine binding.
Topics: Adrenalectomy; Animals; Blood Platelets; Corticosterone; Imipramine; In Vitro Techniques; Kinetics; Male; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes | 1985 |
Inhibition by phenothiazines of adenylate cyclase in adrenal and brain tissue.
Topics: Adenylyl Cyclase Inhibitors; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Brain; Cells, Cultured; Chlorpromazine; Corticosterone; Cyclic AMP; Enzyme Activation; Epinephrine; Hippocampus; Histamine; Imipramine; In Vitro Techniques; Phenothiazines; Phosphorus Radioisotopes; Tritium | 1974 |
[Drugs and glaucoma as contraindication].
Topics: Analgesics; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents; Corticosterone; Glaucoma; Humans; Imipramine; Intraocular Pressure; Sulfonamides; Tranquilizing Agents; Vasodilator Agents | 1974 |
Daily rhythmic variation and liver drug metabolism in rats.
Topics: Aminopyrine; Animals; Anisoles; Circadian Rhythm; Corticosterone; Ethers; Female; Hexobarbital; Imipramine; Liver; Microsomes, Liver; Nitro Compounds; Phenols; Rats; Rats, Inbred Strains | 1971 |
Further studies on a novel animal model of depression: therapeutic effects of a tricyclic antidepressant.
Topics: Acute Disease; Animals; Chronic Disease; Corticosterone; Defecation; Depression; Disease Models, Animal; Humans; Imipramine; Male; Motor Activity; Rats; Reaction Time | 1981 |
Effects of chronic antidepressant treatment on the hypothalamic-pituitary-adrenal axis of Wistar rats.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Body Weight; Corticosterone; Hippocampus; Hypothalamo-Hypophyseal System; Imipramine; Kinetics; Male; Mianserin; Mirtazapine; Pituitary-Adrenal System; Rats; Rats, Wistar; Receptors, Glucocorticoid; Reference Values | 1994 |
Time course of the effects of adrenalectomy and corticosterone replacement on 5-HT1A receptors and 5-HT uptake sites in the hippocampus and dorsal raphe nucleus of the rat brain: an autoradiographic analysis.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenalectomy; Animals; Autoradiography; Corticosterone; Hippocampus; Imipramine; Male; Pyramidal Cells; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Time Factors | 1994 |
The effect of long-term treatment with antidepressant drugs on the hippocampal mineralocorticoid and glucocorticoid receptors in rats.
Topics: Amitriptyline; Androstanols; Animals; Antidepressive Agents; Corticosterone; Hippocampus; Imipramine; Kinetics; Male; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Up-Regulation | 1993 |
Indole-pyruvic acid, a tryptophan ketoanalogue, antagonizes the endocrine but not the behavioral effects of repeated stress in a model of depression.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Antidepressive Agents; Arousal; Corticosterone; Depressive Disorder; Exploratory Behavior; Hippocampus; Imipramine; Immunoenzyme Techniques; Indoles; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Serotonin; Stress, Psychological | 1993 |
Stress and antidepressant effects on hippocampal and cortical 5-HT1A and 5-HT2 receptors and transport sites for serotonin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Autoradiography; Carrier Proteins; Cerebral Cortex; Corticosterone; Hippocampus; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Restraint, Physical; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stress, Psychological; Thiazepines | 1993 |
Attenuation of hypercortisolemia in fawn-hooded rats by antidepressant drugs.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Antidepressive Agents; Clomipramine; Clorgyline; Corticosterone; Imipramine; Male; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Species Specificity | 1993 |
Differential effects of chronic antidepressant treatment on swim stress- and fluoxetine-induced secretion of corticosterone and progesterone.
Topics: Animals; Antidepressive Agents; Corticosterone; Fluoxetine; Imipramine; Male; Phenelzine; Progesterone; Rats; Rats, Sprague-Dawley; Stress, Physiological; Swimming | 1998 |
[Putative contribution of the epiphyseal-adrenocortical system in the antidepressive effect of imipramine].
Topics: Adrenal Cortex; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Depression; Drug Interactions; Imipramine; Pineal Gland; Rats; Reserpine | 1998 |
The effect of chronic administration of antidepressants on the circadian pattern of corticosterone in the rat.
Topics: Animals; Antidepressive Agents; Circadian Rhythm; Clomipramine; Corticosterone; Desipramine; Hypothalamo-Hypophyseal System; Imipramine; Male; Phenelzine; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley | 1998 |
Effects of chronic mild stress (CMS) and imipramine administration, on spleen mononuclear cell proliferative response, serum corticosterone level and brain norepinephrine content in male mice.
Topics: Adrenergic Uptake Inhibitors; Animals; Brain; Cell Division; Chronic Disease; Corticosterone; Dietary Sucrose; Hippocampus; Hypothalamus; Imipramine; Male; Mice; Norepinephrine; Spleen; Stress, Physiological | 1999 |
Antidepressant drugs inhibit glucocorticoid receptor-mediated gene transcription - a possible mechanism.
Topics: Amantadine; Animals; Antidepressive Agents; Cell Line, Transformed; Chloramphenicol O-Acetyltransferase; Cocaine; Corticosterone; Cyclic AMP; Cyclic GMP; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Estrenes; Gene Expression Regulation; Imipramine; Lithium Chloride; Memantine; Mifepristone; Protein Kinase Inhibitors; Pyrrolidinones; Receptors, Glucocorticoid; Receptors, Steroid; Sulfonamides; Tamoxifen; Thionucleotides; Time Factors; Transcription, Genetic; Type C Phospholipases | 2000 |
Effects of antidepressant drugs on the behavioral and physiological responses to lipopolysaccharide (LPS) in rodents.
Topics: Adrenal Glands; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Behavior, Animal; Body Temperature; Brain; Corticosterone; Cytokines; Drug Administration Schedule; Drug Interactions; Fluoxetine; Hypothalamo-Hypophyseal System; Imipramine; Immune System; Lipopolysaccharides; Male; Neuroimmunomodulation; Rats; Rats, Inbred F344; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Spleen | 2001 |
Opposite effects of antidepressants and corticosterone on the sensitivity of hippocampal CA1 neurons to 5-HT1A and 5-HT4 receptor activation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Corticosterone; Electroshock; Free Radical Scavengers; Hippocampus; Imipramine; Male; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2001 |
Pharmacological and endocrine effects of Hypericum perforatum and hypericin after repeated treatment.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Anthracenes; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antioxidants; Biflavonoids; Catechin; Corticosterone; Endocrine System; Exploratory Behavior; Hypericum; Imipramine; Luteinizing Hormone; Male; Organ Size; Perylene; Pituitary Gland; Plant Extracts; Proanthocyanidins; Rats; Rats, Inbred Strains; Seminal Vesicles; Swimming | 2001 |
St John's wort, hypericin, and imipramine: a comparative analysis of mRNA levels in brain areas involved in HPA axis control following short-term and long-term administration in normal and stressed rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Anthracenes; Antidepressive Agents; Arginine Vasopressin; Brain; Brain-Derived Neurotrophic Factor; Corticosterone; Corticotropin-Releasing Hormone; Cyclic AMP Response Element-Binding Protein; Drug Administration Schedule; Glutamate Decarboxylase; Hippocampus; Hypericum; Hypothalamo-Hypophyseal System; Imipramine; In Situ Hybridization; Isoenzymes; Locus Coeruleus; Male; Paraventricular Hypothalamic Nucleus; Perylene; Pituitary Gland; Plants, Medicinal; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reference Values; Restraint, Physical; RNA, Messenger; Stress, Psychological; Transcription, Genetic; Tyrosine 3-Monooxygenase | 2001 |
Postnatal maternal deprivation aggravates experimental autoimmune encephalomyelitis in adult Lewis rats: reversal by chronic imipramine treatment.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Corticosterone; Encephalomyelitis, Autoimmune, Experimental; Female; Imipramine; Interferon-gamma; Interleukin-10; Interleukin-4; Maternal Deprivation; Rats; Rats, Inbred Lew; Time Factors | 2002 |
Differential effect of a single high dose of the tricyclic antidepressant imipramine on interleukin-1beta and tumor necrosis factor-alpha secretion following an in vivo lipopolysaccharide challenge in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Corticosterone; Imipramine; Interleukin-1; Interleukin-10; Lipopolysaccharides; Male; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1999 |
ADRENOCORTICAL AND ENZYMIC EFFECTS OF IMIPRAMINE AND CHLORPROMAZINE.
Topics: Adrenal Glands; Ascorbic Acid; Biochemical Phenomena; Biochemistry; Chlorpromazine; Corticosterone; Imipramine; Mixed Function Oxygenases; Pharmacology; Rats; Research; Transaminases; Tyrosine Transaminase | 1965 |
The prototypic antidepressant drug, imipramine, but not Hypericum perforatum (St. John's Wort), reduces HPA-axis function in the rat.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Corticosterone; Hypericum; Hypothalamus; Imipramine; Male; Pituitary Gland; Plant Extracts; Rats; Rats, Sprague-Dawley | 2003 |
Effects of triiodothyronine on 5-HT(1A) and 5-HT(1B) autoreceptor activity, and postsynaptic 5-HT(1A) receptor activity, in rat hypothalamus: lack of interaction with imipramine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Autoreceptors; Corticosterone; Drug Interactions; Hypothalamus; Imipramine; Male; Microdialysis; Microinjections; Rats; Rats, Inbred Strains; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Serotonin Receptor Agonists; Synaptic Transmission; Triiodothyronine | 2004 |
Effects of rolipram, a phosphodiesterase 4 inhibitor, in combination with imipramine on depressive behavior, CRE-binding activity and BDNF level in learned helplessness rats.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corpus Striatum; Corticosterone; Cyclic AMP Response Element-Binding Protein; Cyclic Nucleotide Phosphodiesterases, Type 4; Depressive Disorder; Drug Synergism; Electrophoretic Mobility Shift Assay; Electroshock; Enzyme-Linked Immunosorbent Assay; Escape Reaction; Frontal Lobe; Helplessness, Learned; Hippocampus; Imipramine; Male; Phosphodiesterase Inhibitors; Protein Binding; Rats; Rats, Sprague-Dawley; Rolipram | 2004 |
Effect of combined treatment with imipramine and metyrapone on the immobility time, the activity of hypothalamo-pituitary-adrenocortical axis and immunological parameters in the forced swimming test in the rat.
Topics: Animals; Corticosterone; Depressive Disorder; Drug Therapy, Combination; Hypothalamo-Hypophyseal System; Imipramine; Immobilization; Male; Metyrapone; Pituitary-Adrenal System; Rats; Rats, Wistar; Swimming | 2005 |
Effect of amantadine and imipramine on immunological parameters of rats subjected to a forced swimming test.
Topics: Amantadine; Animals; Cell Proliferation; Corticosterone; Cytokines; Depressive Disorder; Drug Therapy, Combination; Imipramine; Immobilization; Male; Organ Size; Rats; Rats, Wistar; Spleen; Swimming; Thymus Gland | 2006 |
Imipramine treatment ameliorates corticosterone-induced alterations in the effects of 5-HT1A and 5-HT4 receptor activation in the CA1 area of rat hippocampus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Tricyclic; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Corticosterone; Electric Stimulation; Hippocampus; Imipramine; In Vitro Techniques; Male; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists | 2006 |
Impairment of the spatial learning and memory induced by learned helplessness and chronic mild stress.
Topics: Animals; Base Sequence; Brain-Derived Neurotrophic Factor; Chronic Disease; Corticosterone; Cyclic AMP Response Element-Binding Protein; DNA Primers; Fluoxetine; Imipramine; Learning; Male; Memory; Mice; Mice, Inbred ICR; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stress, Physiological | 2006 |
Imipramine and citalopram reverse corticosterone-induced alterations in the effects of the activation of 5-HT(1A) and 5-HT(2) receptors in rat frontal cortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Citalopram; Corticosterone; Depression; Frontal Lobe; Imipramine; Male; Models, Animal; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT2; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Psychological | 2006 |
Modeling the anxiety-depression continuum hypothesis in domestic fowl chicks.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Chickens; Chlordiazepoxide; Corticosterone; Depression; Disease Models, Animal; Imipramine; Male; Social Isolation; Stress, Psychological; Vocalization, Animal | 2006 |
Effects of imipramine on extracellular serotonin and noradrenaline concentrations in ACTH-treated rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Adrenocorticotropic Hormone; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Imipramine; Male; Norepinephrine; Prefrontal Cortex; Rats; Rats, Wistar; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists | 2007 |
Hypothalamus-pituitary-adrenal modifications consequent to chronic stress exposure in an experimental model of depression in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Corticosterone; Corticotropin-Releasing Hormone; Depression; Dexamethasone; Disease Models, Animal; Escape Reaction; Gene Expression Regulation; Hypothalamo-Hypophyseal System; Imipramine; Male; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Receptors, Glucocorticoid; Stress, Psychological | 2007 |
Antidepressant drugs reverse the loss of adult neural stem cells following chronic stress.
Topics: Animals; Antidepressive Agents; Biological Assay; Cell Death; Cells, Cultured; Chronic Disease; Corticosterone; Disease Models, Animal; Fluoxetine; Glucocorticoids; Imipramine; Lateral Ventricles; Male; Mice; Mice, Inbred ICR; Nerve Degeneration; Olfactory Bulb; Selective Serotonin Reuptake Inhibitors; Serotonin; Spheroids, Cellular; Stem Cells; Stress, Psychological; Swimming; Telencephalon | 2007 |
Repeated social defeat-induced depression-like behavioral and biological alterations in rats: involvement of cholecystokinin.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Bromodeoxyuridine; Cell Proliferation; Cholecystokinin; Corticosterone; Depression; Disease Models, Animal; Dominance-Subordination; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hippocampus; Imipramine; Male; Microdialysis; Phosphopyruvate Hydratase; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Social Environment; Swimming | 2008 |
Chronic low dose corticosterone exposure decreased hippocampal cell proliferation, volume and induced anxiety and depression like behaviours in mice.
Topics: Adrenal Glands; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antimetabolites; Anxiety; Behavior, Animal; Bromodeoxyuridine; Cell Proliferation; Chemistry, Pharmaceutical; Corticosterone; Depression; Fluoxetine; Hippocampus; Imipramine; Immunohistochemistry; Lighting; Male; Mice; Organ Size; Swimming | 2008 |
Effects of acute or 3-day treatments of Hypericum caprifoliatum Cham. & Schltdt. (Guttiferae) extract or of two established antidepressants on basal and stress-induced increase in serum and brain corticosterone levels.
Topics: Animals; Antidepressive Agents; Bupropion; Cerebral Cortex; Corticosterone; Cyclohexanes; Drug Administration Schedule; Humans; Hypericum; Imipramine; Mice; Mice, Inbred Strains; Motor Activity; Plant Extracts; Restraint, Physical; Swimming | 2008 |
Antidepressant-like effects of melatonin in the mouse chronic mild stress model.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Chronic Disease; Circadian Rhythm; Corticosterone; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Hypothalamo-Hypophyseal System; Imipramine; Male; Melatonin; Mice; Mice, Inbred BALB C; Pituitary-Adrenal System; Stress, Psychological | 2009 |
Deficit in BDNF does not increase vulnerability to stress but dampens antidepressant-like effects in the unpredictable chronic mild stress.
Topics: Aggression; Animals; Antidepressive Agents, Tricyclic; Anxiety; Body Weight; Brain-Derived Neurotrophic Factor; Corticosterone; Dentate Gyrus; Eating; Exploratory Behavior; Genotype; Imipramine; Mice; Motor Activity; RNA, Messenger; Stress, Psychological; Time Factors | 2009 |
Curcumin reverses impaired cognition and neuronal plasticity induced by chronic stress.
Topics: Animals; Antidepressive Agents, Tricyclic; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Cognition Disorders; Corticosterone; Curcumin; Hippocampus; Imipramine; Learning Disabilities; Male; Maze Learning; Memory Disorders; Neuronal Plasticity; Neuroprotective Agents; Pyramidal Cells; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Space Perception; Stress, Psychological | 2009 |
Glucocorticoid status affects antidepressant regulation of locus coeruleus tyrosine hydroxylase and dorsal raphé tryptophan hydroxylase gene expression.
Topics: Adrenalectomy; Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Corticosterone; Gene Expression; Image Processing, Computer-Assisted; Imipramine; In Situ Hybridization; Locus Coeruleus; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Phenelzine; Raphe Nuclei; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Messenger; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase; Up-Regulation; Ventral Tegmental Area | 2009 |
Imipramine counteracts corticosterone-induced alterations in the effects of the activation of 5-HT(7) receptors in rat hippocampus.
Topics: Animals; Antidepressive Agents, Tricyclic; Binding Sites; Corticosterone; Dose-Response Relationship, Drug; Drug Antagonism; Hippocampus; Imipramine; In Vitro Techniques; Male; Phenols; Piperazines; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides | 2009 |
Depressive-like parameters in sepsis survivor rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Body Weight; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Disease Models, Animal; Food Preferences; Hippocampus; Imipramine; Male; Organ Size; Rats; Rats, Wistar; Sepsis | 2010 |
Effect of imipramine on nerve excitability in GC rats.
Topics: Administration, Oral; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Catatonia; Corticosterone; Disease Models, Animal; Hydroxyindoleacetic Acid; Imipramine; Male; Norepinephrine; Radioimmunoassay; Rats; Rats, Wistar; Serotonin | 2009 |
Neonatal exposure to constant light prevents anhedonia-like behavior induced by constant light exposure in adulthood.
Topics: Affective Symptoms; Age Factors; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Behavior, Animal; Corticosterone; Disease Models, Animal; Female; Food Preferences; Imipramine; Light; Male; Motor Activity; Rats; Rats, Wistar | 2011 |
Reduction in hippocampal neurogenesis after social defeat is long-lasting and responsive to late antidepressant treatment.
Topics: Adult; Animals; Antidepressive Agents, Tricyclic; Cell Differentiation; Cell Survival; Conditioning, Classical; Corticosterone; Depressive Disorder, Major; Dominance-Subordination; Doublecortin Domain Proteins; Doublecortin Protein; Hippocampus; Humans; Imipramine; Male; Microtubule-Associated Proteins; Neurogenesis; Neuropeptides; Rats; Rats, Wistar; Stress, Psychological | 2011 |
Do stress hormones connect environmental effects with behavior in the forced swim test?
Topics: Adaptation, Psychological; Adrenocorticotropic Hormone; Animals; Behavior, Animal; Body Temperature; Body Weight; Corticosterone; Darkness; Depression; Heart Rate; Hot Temperature; Imipramine; Male; Rats; Stress, Psychological; Swimming | 2011 |
Vulnerability to depression: from brain neuroplasticity to identification of biomarkers.
Topics: Animals; Antidepressive Agents, Tricyclic; Biomarkers; Brain; Brain-Derived Neurotrophic Factor; Cell Proliferation; Competitive Behavior; Corticosterone; Depressive Disorder; Hippocampus; Hypothalamo-Hypophyseal System; Imipramine; Longitudinal Studies; Male; Neuronal Plasticity; Neurons; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Social Environment; Stress, Psychological; Swimming; Taste | 2011 |
Effects of chronic corticosterone and imipramine administration on panic and anxiety-related responses.
Topics: Animals; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; Corticosterone; Escape Reaction; Imipramine; Male; Maze Learning; Motor Activity; Panic Disorder; Rats; Rats, Wistar | 2011 |
Imipramine reverses depressive-like parameters in pneumococcal meningitis survivor rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Anhedonia; Animals; Antidepressive Agents, Tricyclic; Body Weight; Corticosterone; Depressive Disorder; Eating; Exploratory Behavior; Hippocampus; Imipramine; Male; Meningitis, Pneumococcal; Motor Activity; Rats; Rats, Wistar; Streptococcus pneumoniae; Survivors; Tumor Necrosis Factor-alpha | 2012 |
Imipramine counteracts corticosterone-induced enhancement of glutamatergic transmission and impairment of long-term potentiation in the rat frontal cortex.
Topics: Animals; Corticosterone; Frontal Lobe; Glutamic Acid; Imipramine; Long-Term Potentiation; Male; Rats; Rats, Wistar; Synaptic Transmission | 2011 |
HDAC6 regulates glucocorticoid receptor signaling in serotonin pathways with critical impact on stress resilience.
Topics: Animals; Behavior, Animal; Brain; Cells, Cultured; Corticosterone; Dexamethasone; Disease Models, Animal; Gene Deletion; Gene Expression Regulation; Histone Deacetylase 6; Histone Deacetylases; HSP90 Heat-Shock Proteins; Imipramine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Chaperones; Raphe Nuclei; Receptors, Glucocorticoid; Resilience, Psychological; Serotonergic Neurons; Signal Transduction; Stress, Psychological | 2012 |
NADPH oxidase mediates depressive behavior induced by chronic stress in mice.
Topics: Acetophenones; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Antioxidants; Ascorbic Acid; Brain; Cell Line; Corticosterone; Depressive Disorder; Disease Models, Animal; Drug Administration Schedule; Gene Expression Regulation, Enzymologic; Green Fluorescent Proteins; Hindlimb Suspension; Hippocampus; Humans; Hydrogen Peroxide; Imipramine; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADPH Oxidases; Neuroblastoma; Neurons; Phosphoproteins; Reactive Oxygen Species; Restraint, Physical; RNA, Messenger; RNA, Small Interfering; Social Behavior; Superoxides; Swimming; Time Factors | 2012 |
Effects of chronic treatment with corticosterone and imipramine on fos immunoreactivity and adult hippocampal neurogenesis.
Topics: Amygdala; Animals; Corticosterone; Doublecortin Domain Proteins; Doublecortin Protein; Hippocampus; Hypothalamus; Imipramine; Male; Microtubule-Associated Proteins; Neurogenesis; Neurons; Neuropeptides; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar | 2013 |
Chronic adrenocorticotrophic hormone treatment alters tricyclic antidepressant efficacy and prefrontal monoamine tissue levels.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Biogenic Monoamines; Corticosterone; Drug Administration Schedule; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Exploratory Behavior; Freezing Reaction, Cataleptic; Grooming; Imipramine; Male; Peptide Fragments; Prefrontal Cortex; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Swimming; Time Factors | 2013 |
Antidepressant-like effects of paeoniflorin on the behavioural, biochemical, and neurochemical patterns of rats exposed to chronic unpredictable stress.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Behavior, Animal; Benzoates; Biogenic Monoamines; Brain; Bridged-Ring Compounds; Chronic Disease; Corticosterone; Glucosides; Imipramine; Male; Monoterpenes; Rats; Rats, Sprague-Dawley; Stress, Psychological | 2013 |
Additive antidepressant-like effects of fasting with imipramine via modulation of 5-HT2 receptors in the mice.
Topics: Amphetamines; Animals; Antidepressive Agents, Tricyclic; Brain; Corticosterone; CREB-Binding Protein; Fasting; Gene Expression Regulation; Imipramine; Immobility Response, Tonic; Male; Mice; Mice, Inbred ICR; Motor Activity; Norepinephrine; Receptors, Serotonin, 5-HT2; Serotonin; Serotonin Receptor Agonists; Time Factors | 2014 |
Pitx3 deficient mice as a genetic animal model of co-morbid depressive disorder and parkinsonism.
Topics: Anhedonia; Animals; Antidepressive Agents; Brain; Comorbidity; Corticosterone; Depressive Disorder; Dietary Sucrose; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking Behavior; Female; Gene Expression Regulation; Genes, fos; Homeodomain Proteins; Imipramine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Parkinsonian Disorders; Proto-Oncogene Proteins c-fos; Restraint, Physical; Stress, Psychological; Transcription Factors | 2014 |
The selective glucocorticoid receptor antagonist CORT 108297 decreases neuroendocrine stress responses and immobility in the forced swim test.
Topics: Animals; Antidepressive Agents, Tricyclic; Aza Compounds; Behavior, Animal; Corticosterone; Heterocyclic Compounds, 4 or More Rings; Hormone Antagonists; Imipramine; Male; Mifepristone; Rats; Rats, Sprague-Dawley; Stress, Psychological | 2014 |
Effects of aspirin on immobile behavior and endocrine and immune changes in the forced swimming test: comparison to fluoxetine and imipramine.
Topics: Animals; Antidepressive Agents; Aspirin; Behavior, Animal; Corticosterone; Endocrine Glands; Fluoxetine; Imipramine; Immune System; Interleukin-6; Male; Rats; Rats, Sprague-Dawley; Swimming; Tumor Necrosis Factor-alpha | 2014 |
Lipopolysaccharide repeated challenge followed by chronic mild stress protocol introduces a combined model of depression in rats: reversibility by imipramine and pentoxifylline.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Gene Expression; Hippocampus; Imipramine; Kynurenine; Lipopolysaccharides; Male; Pentoxifylline; Rats; Stress, Psychological; Tryptophan; Tumor Necrosis Factor-alpha | 2014 |
Effects of N-acetylcysteine and imipramine in a model of acute rhythm disruption in BALB/c mice.
Topics: Acetylcysteine; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Circadian Rhythm; Corticosterone; Depression; Disease Models, Animal; Imipramine; Interleukin-6; Light; Male; Mice; Mice, Inbred BALB C; Motor Activity; Photoperiod; Rest; Social Behavior; Temperature; Time Factors | 2015 |
Increased antidepressant sensitivity after prefrontal cortex glucocorticoid receptor gene deletion in mice.
Topics: Animals; Antidepressive Agents; Corticosterone; Depressive Disorder; Disease Models, Animal; Gene Knockdown Techniques; Hypothalamo-Hypophyseal System; Imipramine; Immunohistochemistry; Male; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Pituitary-Adrenal System; Prefrontal Cortex; Receptors, Glucocorticoid; Stress, Psychological; Swimming | 2015 |
Imipramine protects against the deleterious effects of chronic corticosterone on depression-like behavior, hippocampal reelin expression, and neuronal maturation.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents, Tricyclic; Cell Adhesion Molecules, Neuronal; Corticosterone; Dendrites; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Doublecortin Domain Proteins; Extracellular Matrix Proteins; Gene Expression Regulation; Hippocampus; Imipramine; Immobility Response, Tonic; Male; Mice; Mice, Neurologic Mutants; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurons; Neuropeptides; Rats; Rats, Long-Evans; Reelin Protein; Serine Endopeptidases; Swimming | 2015 |
Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice.
Topics: Agmatine; Anhedonia; Animals; Antidepressive Agents; Astrocytes; Behavior, Animal; Biomarkers; Corticosterone; Depression; Female; Hippocampus; Imipramine; Mice, Inbred C57BL; Microglia; Models, Biological; Neuronal Plasticity; Neurotransmitter Agents; NF-E2-Related Factor 2; Signal Transduction | 2016 |
[Comparative analysis of imipramine intake reactions in catatonic and wistar rats].
Topics: Acoustic Stimulation; Animals; Body Weight; Catatonia; Corpus Striatum; Corticosterone; Imipramine; Male; Norepinephrine; Rats; Rats, Wistar; Triglycerides | 2015 |
Antidepressant-like activity of plumbagin in unstressed and stressed mice.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antioxidants; Behavior, Animal; Brain; Corticosterone; Depression; Hindlimb Suspension; Imipramine; Male; Mice; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Motor Activity; Naphthoquinones; Stress, Psychological | 2015 |
The Role of Nitric Oxide in the Antidepressant Actions of 5-Aminoimidazole-4-Carboxamide-1-β-D-Ribofuranoside in Insulin-Resistant Mice.
Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Antidepressive Agents; Combined Modality Therapy; Corticosterone; Depressive Disorder; Diet, High-Fat; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Activation; Fluoxetine; Imipramine; Insulin Resistance; Ketamine; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Physical Conditioning, Animal; Prefrontal Cortex; Ribonucleotides; Triazenes | 2016 |
Testosterone has antidepressant-like efficacy and facilitates imipramine-induced neuroplasticity in male rats exposed to chronic unpredictable stress.
Topics: Animals; Antidepressive Agents; Chronic Disease; Corticosterone; Dentate Gyrus; Depression; Disease Models, Animal; Hippocampus; Hypothalamo-Hypophyseal System; Imipramine; Male; Neurogenesis; Neuronal Plasticity; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Stress, Psychological; Testosterone | 2016 |
Zinc and imipramine reverse the depression-like behavior in mice induced by chronic restraint stress.
Topics: Animals; Brain-Derived Neurotrophic Factor; Corticosterone; CREB-Binding Protein; Depression; Depressive Disorder; Drug Synergism; Hippocampus; Imipramine; Male; Mice; Receptors, G-Protein-Coupled; Receptors, N-Methyl-D-Aspartate; Restraint, Physical; Signal Transduction; Stress, Psychological; Zinc | 2016 |
Fourteen-day administration of corticosterone may induce detrusor overactivity symptoms.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Depression; Disease Models, Animal; Female; Fluoxetine; Imipramine; Muscarinic Antagonists; Random Allocation; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Selective Serotonin Reuptake Inhibitors; Urinary Bladder; Urinary Bladder, Overactive | 2016 |
Antidepressant imipramine diminishes stress-induced inflammation in the periphery and central nervous system and related anxiety- and depressive- like behaviors.
Topics: Animals; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; Corticosterone; Depression; Imipramine; Inflammation; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Myeloid Progenitor Cells; Spleen; Stress, Psychological | 2016 |
Depression-Like Adult Behaviors may be a Long-Term Result of Experimental Pneumococcal Meningitis in Wistar Rats Infants.
Topics: Animals; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Disease Models, Animal; Hippocampus; Imipramine; Male; Meningitis, Pneumococcal; Rats, Wistar; Time | 2016 |
A mixed glucocorticoid/mineralocorticoid receptor modulator dampens endocrine and hippocampal stress responsivity in male rats.
Topics: Amygdala; Animals; Corticosterone; Depression; Hippocampus; Hormones; Imipramine; Male; Motor Activity; Neurons; Paraventricular Hypothalamic Nucleus; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Psychotropic Drugs; Random Allocation; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Stress, Psychological; Thymine | 2017 |
Methyl jasmonate attenuated lipopolysaccharide-induced depressive-like behaviour in mice.
Topics: Acetates; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain; Corticosterone; Cyclopentanes; Depression; Disease Models, Animal; Imipramine; Infusions, Parenteral; Jasminum; Lipopolysaccharides; Male; Mice; Oxidative Stress; Oxylipins; Plant Extracts; Tumor Necrosis Factor-alpha | 2017 |
Differential effects of imipramine and CORT118335 (Glucocorticoid receptor modulator/mineralocorticoid receptor antagonist) on brain-endocrine stress responses and depression-like behavior in female rats.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain; Corticosterone; Depression; Depressive Disorder; Female; Hippocampus; Hypothalamo-Hypophyseal System; Hypothalamus; Imipramine; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal System; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Stress, Physiological; Stress, Psychological; Thymine | 2018 |
Methyl Jasmonate Ameliorates Unpredictable Chronic Mild Stress-Induced Behavioral and Biochemical Alterations in Mouse Brain.
Topics: Acetates; Animals; Behavior, Animal; Brain; Corticosterone; Cyclopentanes; Disease Models, Animal; Glutathione; Imipramine; Male; Malondialdehyde; Mice; Oxylipins; Stress, Psychological; Superoxide Dismutase; Treatment Outcome; Tumor Necrosis Factor-alpha | 2017 |
Esketamine and rapastinel, but not imipramine, have antidepressant-like effect in a treatment-resistant animal model of depression.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depressive Disorder, Treatment-Resistant; Disease Models, Animal; Imipramine; Ketamine; Male; Oligopeptides; Rats; Rats, Sprague-Dawley; Swimming; Treatment Outcome | 2019 |
Neonatal Immune Activation May Provoke Long-term Depressive Attributes.
Topics: Animals; Animals, Newborn; Corticosterone; Depression; Depressive Disorder; Disease Models, Animal; Hippocampus; Imipramine; Lipopolysaccharides; Mice, Inbred C57BL; Time | 2019 |
A comparative analysis of depressive-like behavior: Exploring sex-related differences and insights.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Female; Fluoxetine; Hindlimb Suspension; Imipramine; Male; Mice; Swimming | 2023 |