imipramine has been researched along with cocaine in 171 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 113 (66.08) | 18.7374 |
| 1990's | 25 (14.62) | 18.2507 |
| 2000's | 24 (14.04) | 29.6817 |
| 2010's | 9 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sen, S; Sinha, N | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Butler, DE; L'Italien, YJ; Marriott, JG; Nordin, IC; Poschel, PH; Zweisler, L | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M | 1 |
| Keserü, GM | 1 |
| Li, J; Rajamani, R; Reynolds, CH; Tounge, BA | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Adkins, S; Duval, RA; Foster, JD; Hauck-Newman, A; Kulkarni, SS; Lever, JR; Parnas, ML; Sakrikar, DS; Vaughan, RA | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Cooper, RA; Dodean, RA; Hinrichs, DJ; Janowsky, A; Johnson, RA; Kelly, JX; Lane, KD; Riscoe, M; Smilkstein, MJ; Winter, R | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Jia, L; Sun, H | 1 |
| Caron, G; Ermondi, G; Visentin, S | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Dolzhenko, AT | 1 |
| Allan, D; Michell, RH | 1 |
| Bates, A; Shuster, L; Yu, G | 1 |
| Bakhanashvili, TA; Maĭsov, NI; Zharikova, AD | 1 |
| Aleksidze, NG; Bakhanashvili, TA; Maĭsov, NI; Raevskiĭ, KS | 1 |
| Oxterwalder, M; Schönenberger, E; Waser, PG | 1 |
| Gero, J; Gerová, M | 1 |
| Moore, KE; Wuerthele, SM | 1 |
| Kelder, D; Ross, SB | 1 |
| Evans, S; Steiner, G | 1 |
| Miranda, H | 1 |
| Da Prada, M; Picotti, GB; Pletscher, A | 1 |
| Pickens, R; Thompson, T | 1 |
| Davila, D; Davila, T | 1 |
| Ozawa, H; Uematsu, T | 1 |
| Conde, M; Delgado, JM; Delgado-Garcia, JM; Robles, SS | 1 |
| Anestis, DK; Gruetter, CA; Lemke, SM; Szarek, JL; Valentovic, MA | 1 |
| De Montis, G; Devoto, P; Tagliamonte, A | 1 |
| Glowniak, JV; Joyce, ME; Turner, FE; Wilson, RA | 1 |
| Benmansour, S; Brunswick, DJ; Hauptmann, M; Tejani-Butt, SM | 1 |
| D'Aquila, PS; Gessa, GL; Hmaidan, Y; Rossetti, ZL; Serra, G | 1 |
| Barrett, JE; Zhang, L | 1 |
| Gale, K; Meloni, R | 1 |
| Rudnick, G; Wall, SC | 1 |
| Brady, R; Nunes, EV; Quitkin, FM; Stewart, JW | 1 |
| Rayport, S; Sulzer, D | 1 |
| Chiba, S; Ohkubo, H | 1 |
| Frank, RA; Zubrycki, E | 1 |
| Fukuda, S; Lee, TJ; Su, C | 1 |
| Frank, RA; Nitz, D; Pommering, T | 1 |
| Ilarionov, I | 1 |
| Davis, RS; McNeill, JH | 1 |
| Gazaix, P | 1 |
| Barthel, W | 1 |
| Schuster, CR; Wilson, MC | 1 |
| Goldberg, SR; Hoffmeister, F | 1 |
| Weinstock, M | 1 |
| Coimbra, A; Guimarães, S; Osswald, W | 1 |
| Jansson, SE | 1 |
| Bevan, JA | 1 |
| Bhagat, B; Gilliam, J | 1 |
| Renyi, AL; Ross, SB | 2 |
| Gokhale, SD; Gulati, OD; Udwadia, BP | 1 |
| Mennear, JH; Rudzik, AD | 1 |
| Dhalla, NS | 1 |
| Wesemann, W; Zilliken, F | 1 |
| Gillis, CN; Schneider, FH | 1 |
| Breese, GR; Kopin, IJ; Schanberg, SM; Schildkraut, JJ | 1 |
| Fekete, M; Macsek, I | 1 |
| Kuruma, I; Segawa, T; Takagi, H; Takatsuka, K | 1 |
| Benesová, O | 1 |
| Krnjević, H; Tomljanović, D | 1 |
| Gershon, S; Sanghvi, I | 1 |
| Patil, PN | 1 |
| Bhagat, B; Friedman, E | 1 |
| Grewal, RS; Kaul, CL | 2 |
| Schrold, J | 1 |
| Angelo, LS; Junod, AF; Nicholas, TE; Strum, JM | 1 |
| Federico, R; Levi, G; Raiteri, M | 1 |
| Dubileĭ, PV; Urazaeva, ZV | 1 |
| Contreras, E; Quijada, L; Tamayo, L | 1 |
| Gripenberg, J | 1 |
| Chapman, B; Feldman, JM | 1 |
| Binini, R; Bonaccorsi, A; Garattini, S; Morselli, PL; Muscettola, G | 1 |
| Gillis, CN; Iwasawa, Y | 1 |
| Akers, TK; Hammond, RE | 1 |
| Durell, J; Kopin, IJ; Schanberg, SM; Schildkraut, JJ | 1 |
| Scheel-Krüger, J | 1 |
| Junod, AF | 2 |
| Sjöstrand, SE | 1 |
| Blackburn, KJ; French, PC; Merrills, RJ | 1 |
| Ahonen, A; Pentilä, A | 1 |
| Giachetti, A; Shore, PA | 1 |
| Gorosito, M; Sabelli, HC | 1 |
| Bruinvels, J | 2 |
| Opitz, K; Schniedermann, W | 1 |
| Vohra, MM | 1 |
| Kukk, MA | 1 |
| Quebbemann, A; Rennick, B | 1 |
| Baldessarini, RJ; Vogt, M | 1 |
| Binini, R; Bonaccorsi, A; Garattini, S; Morselli, PL; Muscettola, GB | 1 |
| Lendvai, J; Leszkovszky, GP; Takács, K; Tardos, L | 1 |
| Axelrod, J; Eccleston, D; Thoa, NB | 2 |
| Barnett, A; Greenhouse, DD; Taber, RI | 1 |
| Maître, L; Staehelin, M | 1 |
| Nott, MW | 1 |
| Barnett, A; Symchowicz, S; Taber, RI | 1 |
| Barnett, A; Staub, M; Symchowicz, S | 1 |
| Schroeder, LA; Tang, AH | 1 |
| Blumberg, AG; Heaton, AM | 1 |
| Cairncross, KD; McCulloch, MW; Mitchelson, F | 1 |
| Angel, C; Roberts, AJ | 1 |
| Gankina, EM; Maĭsov, NI | 1 |
| Ceña, V; Garcia, AG; Kirpekar, SM; Nicolas, GP; Sanchez-Garcia, P | 1 |
| Dunwiddie, TV; Yasuda, RP; Zahniser, NR | 1 |
| Lajtha, A; Reith, ME; Sershen, H | 1 |
| Ceña, V; García, AG; Montiel, C; Sánchez-García, P | 1 |
| Allen, DL; Lajtha, A; Reith, ME; Sershen, H | 1 |
| Goyal, RK; Patel, NM; Verma, SC | 1 |
| Kato, S; Yanagita, T | 1 |
| Antelman, SM; Chiodo, LA | 1 |
| Kamiya, H; Kohjimoto, Y; Saito, R; Sakurai, Y; Takano, Y | 1 |
| Catravas, JD; Gillis, CN | 1 |
| Barrett, JE; Zuccarelli, RR | 1 |
| Arqueros, L; Daniels, AJ; Gysling, K | 1 |
| Bhat, GK; Ganapathy, V; Leibach, FH; Mahesh, VB; Prasad, PD; Ramamoorthy, JD; Ramamoorthy, S | 1 |
| Galloway, GP; Knapp, T; Newmeyer, J; Smith, D; Stalcup, SA | 1 |
| Barker, EL; Blakely, RD; Kimmel, HL | 1 |
| Humphreys, CJ; Rudnick, G; Wall, SC | 1 |
| Johnson, JA; Koivunen, DG | 1 |
| Barrett, JE; Sasaki, JE; Tatham, TA | 1 |
| Klein, DF; Koenig, T; McGrath, PJ; Nunes, EV; Ocepek-Welikson, K; Quitkin, FM; Stewart, JW; Wager, S | 1 |
| Borison, RL; Cassano, GB; Diamond, BI; Marazziti, D; Pathiraja, A | 1 |
| Barros, HM; Belej, T; Manji, D; Nobrega, JN; Sioutis, S | 1 |
| Wilkins, JN | 1 |
| Eshleman, AJ; Janowsky, A; Johnson, RA; Meyers, T; Neve, KA | 1 |
| Dart, AM; Du, XJ; Esler, MD; Little, PJ; Woodcock, EA | 1 |
| Blakely, RD; Jansen, K; Richelson, E; Tatsumi, M | 1 |
| De Montis, MG; Gambarana, C; Ghiglieri, O; Masi, F; Scheggi, S; Tagliamonte, A | 1 |
| Barker, EL; Blakely, RD; Moore, KR; Rakhshan, F | 1 |
| Budziszewska, B; Jaworska-Feil, L; Kajta, M; Lasoń, W | 1 |
| AXELROD, J; INSCOE, JK | 1 |
| BOFF, E; SCHECKEL, CL | 1 |
| LUDDEN, CT; PORTER, CC; STAVORSKI, JM; STONE, CA; TOTARO, JA | 1 |
| EBLE, JN | 1 |
| DAY, M; STOCKBRIDGE, A | 1 |
| SMITH, CB | 1 |
| IVERSEN, LL | 1 |
| JACOBSON, J; URSILLO, RC | 1 |
| MATUSSEK, N; RUETHER, E | 1 |
| SIGG, EB; SIGG, TD | 1 |
| GOKHALE, SD; GULATI, OD; JOSHI, NY | 1 |
| France, CP; McMahon, LR; Sell, SL | 1 |
| France, CP; Koek, W; McMahon, LR; Sell, SL | 1 |
| Endo, S; Gomita, Y; Hamamura, T; Ishihara, T; Kuroda, S; Lee, Y; Miki, M; Miyata, S; Sagara, H; Taoka, H; Toma, K | 1 |
| Kato, M; Nishiyama, S; Oreland, L; Sakurai, E; Watanabe, T; Yanai, K | 1 |
| Guo, B; He, MM; Li, C; Liu, H; Shen, H; Wang, L; Wrighton, SA | 1 |
| Fisar, Z; Velenovská, M | 1 |
| Forrest, LR; Rudnick, G; Tavoulari, S | 1 |
| Filip, M; Frankowska, M; Gołda, A; Gruca, P; Papp, M; Wydra, K | 1 |
| De Montis, MG; Gambarana, C; Grappi, S; Marchese, G; Scheggi, S; Secci, ME | 1 |
| Fisar, Z; Hroudová, J; Raboch, J | 1 |
| Carroll, FI; McMahon, LR; Schulze, DR | 1 |
| Gouda, H; Handa, K; Hirono, S; Nakagome, I; Yamaotsu, N | 1 |
| Filip, M; Frankowska, M; Jastrzębska, J; Nowak, E; Przegaliński, E; Suder, A; Wydra, K | 1 |
1 review(s) available for imipramine and cocaine
| Article | Year |
|---|---|
An experimental analysis of behavioral factors in drug dependence.
Topics: Administration, Oral; Alcoholism; Amphetamine; Animals; Behavior, Animal; Cannabis; Chlorpromazine; Cocaine; Dextroamphetamine; Drinking Behavior; Dronabinol; Ethanol; Humans; Imipramine; Injections, Intravenous; Macaca mulatta; Morphine; Pentobarbital; Reinforcement Schedule; Secobarbital; Social Environment; Substance-Related Disorders; Time Factors | 1975 |
3 trial(s) available for imipramine and cocaine
| Article | Year |
|---|---|
Affective disorders and norepinephrine pharmacology.
Topics: Animals; Behavior; Behavior, Animal; Body Temperature; Brain; Brain Chemistry; Chlorpromazine; Clinical Trials as Topic; Cocaine; Depression; Emotions; Female; Humans; Hypothermia, Induced; Imipramine; Lithium; Male; Methyltyrosines; Middle Aged; Monoamine Oxidase Inhibitors; Norepinephrine; Normetanephrine; Placebos; Rats; Reserpine; Tetrabenazine; Vanilmandelic Acid | 1969 |
Imipramine for the treatment of cocaine and methamphetamine dependence.
Topics: Cocaine; Combined Modality Therapy; Counseling; Dose-Response Relationship, Drug; Double-Blind Method; Feasibility Studies; Female; Follow-Up Studies; Humans; Imipramine; Male; Methamphetamine; Patient Dropouts; Substance Withdrawal Syndrome; Substance-Related Disorders; Treatment Outcome | 1994 |
Imipramine treatment of cocaine abuse: possible boundaries of efficacy.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Tricyclic; Cocaine; Combined Modality Therapy; Comorbidity; Depressive Disorder; Double-Blind Method; Euphoria; Female; Humans; Imipramine; Male; Middle Aged; Motivation; Substance Withdrawal Syndrome; Substance-Related Disorders; Treatment Outcome | 1995 |
167 other study(ies) available for imipramine and cocaine
| Article | Year |
|---|---|
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Amnesia-reversal activity of a series of N-[(disubstituted-amino)alkyl] -2-oxo-1-pyrrolidineacetamides, including pramiracetam.
Topics: Amnesia; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Humans; Male; Mice; Mice, Inbred Strains; Pyrrolidines; Structure-Activity Relationship | 1984 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2002 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
A two-state homology model of the hERG K+ channel: application to ligand binding.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation | 2005 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Localization of cocaine analog [125I]RTI 82 irreversible binding to transmembrane domain 6 of the dopamine transporter.
Topics: Animals; Azides; Cocaine; Cyanogen Bromide; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Epitopes; Humans; Iodine Radioisotopes; Methionine; Protein Binding; Protein Structure, Tertiary; Protein Transport; Rats; Trypsin | 2007 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Design, synthesis, and evaluation of 10-N-substituted acridones as novel chemosensitizers in Plasmodium falciparum.
Topics: Acridones; Animals; Antimalarials; Cell Survival; Cells, Cultured; Drug Design; Drug Interactions; Drug Resistance, Multiple; Lymphocytes; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Molecular Structure; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Structure-Activity Relationship | 2007 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
[Effect of blocking the neuronal and extraneuronal uptake of bioamines on the adrenosensitizing action of tricyclic antidepressants].
Topics: Animals; Antidepressive Agents, Tricyclic; Cocaine; Dibenzazepines; Dose-Response Relationship, Drug; Imipramine; In Vitro Techniques; Male; Muscle Denervation; Muscle, Smooth; Norepinephrine; Oxazines; Rats; Testis | 1976 |
Enhanced synthesis de novo of phosphatidylinositol in lymphocytes treated with cationic amphiphilic drugs.
Topics: Amphetamine; Animals; Cetrimonium Compounds; Chlorpromazine; Cocaine; Dibucaine; Dose-Response Relationship, Drug; Fenfluramine; Imipramine; Lectins; Lymphocytes; Phenethylamines; Phosphatidylinositols; Procaine; Promethazine; Swine; Time Factors; Trifluoperazine | 1975 |
Sensitization to cocaine stimulation in mice.
Topics: Animals; Brain Chemistry; Cocaine; Cycloheximide; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Female; Imipramine; Male; Mice; Mice, Inbred A; Mice, Inbred BALB C; Mice, Inbred C57BL; Morphine; Motor Activity; Norepinephrine; Reserpine; Species Specificity; Stimulation, Chemical; Time Factors | 1977 |
[Inhibition of serotonin uptake in synaptosomes and glia cells by some pharmacological substances].
Topics: Animals; Biological Transport; Cerebral Cortex; Cocaine; Imipramine; Neuroglia; Psychotropic Drugs; Rabbits; Serotonin; Synaptosomes | 1979 |
[Tryptophan uptake by glia and synaptosomes of rabbit cerebral cortex].
Topics: Animals; Cerebral Cortex; Chlorpromazine; Cocaine; Imipramine; Kinetics; Neuroglia; Rabbits; Synaptosomes; Trifluperidol; Tryptophan | 1978 |
Autoradiography of 14C-choline uptake in endplates and skeletal muscle of mice.
Topics: Animals; Autoradiography; Chlorpromazine; Choline; Cocaine; Female; Imipramine; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Motor Endplate; Muscle Denervation; Muscles; Neuromuscular Junction; Reserpine; Time Factors | 1978 |
Mechanisms underlying overshoot dilation after sympathetic denervation.
Topics: Animals; Arteries; Cocaine; Dogs; Female; Femoral Artery; Femoral Vein; Imipramine; Male; Neurons; Norepinephrine; Sympathectomy; Sympathetic Nervous System; Vasodilation; Vasomotor System; Veins | 1978 |
Studies on the mechanisms of L-dopa-induced depletion of 5-hydroxytryptamine in the mouse brain.
Topics: Amines; Animals; Benztropine; Biological Transport; Brain; Clomipramine; Cocaine; Dihydroxyphenylalanine; Dopamine; Imipramine; Levodopa; Male; Mice; Mice, Inbred ICR; Serotonin; Tryptophan | 1977 |
Active transport of 3H-bretylium in the rat vas deferens in vitro.
Topics: Aminobenzoates; Amphetamine; Anesthetics, Local; Animals; Biological Transport, Active; Bretylium Compounds; Chlorides; Cocaine; Desipramine; Hydroxybenzoate Ethers; Hydroxydopamines; Imipramine; Lidocaine; Male; meta-Aminobenzoates; Ouabain; Rats; Reserpine; Sodium; Sympathetic Nervous System; Temperature; Vas Deferens | 1976 |
Effect of serotonin on brown adipose tissue and on its sympathetic neurons.
Topics: Adipose Tissue, Brown; Animals; Cocaine; Creatinine; Depression, Chemical; Imipramine; In Vitro Techniques; Male; Norepinephrine; Rats; Serotonin; Sympathetic Nervous System; Sympathomimetics | 1976 |
Vas deferens desensitization by noradrenaline and other drugs.
Topics: Acetylcholine; Animals; Barium; Carbachol; Cocaine; Denervation; Hydroxydopamines; Imipramine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Rats; Reserpine; Serotonin; Vas Deferens | 1976 |
Uptake and liberation of mepacrine in blood platelets.
Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Animals; Blood Platelets; Cell Membrane; Chlorpromazine; Cocaine; Cyanides; Female; Fluorides; Guinea Pigs; Imipramine; In Vitro Techniques; Male; Ouabain; Quinacrine; Reserpine; Serotonin; Temperature; Thrombin | 1976 |
Uptake and release of 3H-metaraminol by rat lung. The influence of various drugs.
Topics: Animals; Cocaine; Desipramine; Female; Imipramine; In Vitro Techniques; Lung; Metaraminol; Ouabain; Rats; Reserpine; Time Factors; Tyramine | 1975 |
[Mode of action of clonidine, a central hypotensive agent, analyzed by the interaction with various sympathomimetic agents].
Topics: Animals; Blood Pressure; Central Nervous System; Chlorpromazine; Clonidine; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Ephedrine; Guanethidine; Guinea Pigs; Haloperidol; Hexamethonium Compounds; Imipramine; In Vitro Techniques; Male; Methamphetamine; Norepinephrine; Rats; Sympathomimetics; Tyramine; Vas Deferens | 1975 |
Fatigability of caudate nucleus stimulation in cats.
Topics: Animals; Catecholamines; Cats; Caudate Nucleus; Cocaine; Differential Threshold; Electric Stimulation; Electrophysiology; Eye Movements; Habituation, Psychophysiologic; Haloperidol; Imipramine; Motor Activity; Movement; Orientation; Reserpine; Time Factors | 1976 |
Potentiation of 5-hydroxytryptamine-induced contraction in rat aorta by chlorpheniramine, citalopram and fluoxetine.
Topics: Animals; Aorta, Thoracic; Chlorpheniramine; Citalopram; Cocaine; Dose-Response Relationship, Drug; Fluoxetine; Histamine H1 Antagonists; Imipramine; In Vitro Techniques; Male; Pargyline; Rats; Rats, Sprague-Dawley; Serotonin; Vasoconstriction | 1992 |
Failure by tricyclic antidepressants to affect the increase of dopamine extracellular concentrations produced by haloperidol in the caudate and accumbens nuclei of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Antidepressive Agents, Tricyclic; Caudate Nucleus; Cocaine; Dopamine; Drug Interactions; Haloperidol; Imipramine; Male; Nucleus Accumbens; Piperazines; Rats; Rats, Inbred Strains | 1992 |
Evaluation of metaiodobenzylguanidine heart and lung extraction fraction by first-pass analysis in pigs.
Topics: 3-Iodobenzylguanidine; Animals; Cocaine; Coronary Circulation; Dipyridamole; Heart; Imipramine; Iodine Radioisotopes; Iodobenzenes; Lung; Radionuclide Imaging; Swine; Sympatholytics; Technetium Tc 99m Aggregated Albumin | 1992 |
Lack of effect of high-dose cocaine on monoamine uptake sites in rat brain measured by quantitative autoradiography.
Topics: Animals; Autoradiography; Biogenic Monoamines; Brain Chemistry; Cocaine; Imipramine; In Vitro Techniques; Male; Mazindol; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Serotonin; Serotonin Antagonists | 1992 |
Repeated treatment with imipramine potentiates cocaine-induced dopamine release and motor stimulation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Corpus Striatum; Dopamine; Drug Synergism; Homovanillic Acid; Imipramine; Male; Motor Activity; Rats; Rats, Inbred Strains; Stimulation, Chemical; Synaptic Transmission | 1991 |
Imipramine as a discriminative stimulus.
Topics: Amitriptyline; Amphetamine; Animals; Bupropion; Cocaine; Columbidae; Discrimination Learning; Dose-Response Relationship, Drug; Imipramine | 1991 |
Cocaine-induced turning behavior in rats with 6-hydroxydopamine lesions: effect of transplants of fetal substantia nigra.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Diseases; Brain Tissue Transplantation; Cocaine; Dopamine; Fetal Tissue Transplantation; Fluoxetine; Imipramine; Male; Neural Pathways; Neurotransmitter Uptake Inhibitors; Nomifensine; Oxidopamine; Piperazines; Rats; Rats, Inbred Strains; Substantia Nigra | 1991 |
Binding of the cocaine analog 2 beta-[3H] carboxymethoxy-3 beta-(4-fluorophenyl)tropane to the serotonin transporter.
Topics: Biological Transport; Blood Proteins; Carrier Proteins; Chlorides; Cocaine; Humans; Hydrogen-Ion Concentration; Imipramine; Potassium; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sodium | 1991 |
Imipramine treatment of methadone maintenance patients with affective disorder and illicit drug use.
Topics: Adult; Cocaine; Depressive Disorder; Drug Therapy, Combination; Female; Heroin Dependence; Humans; Imipramine; Male; Methadone; Pilot Projects; Substance Abuse, Intravenous; Substance-Related Disorders | 1991 |
Amphetamine and other psychostimulants reduce pH gradients in midbrain dopaminergic neurons and chromaffin granules: a mechanism of action.
Topics: Amphetamine; Animals; Cells, Cultured; Chromaffin Granules; Cocaine; Dopamine; Fenfluramine; Hydrogen-Ion Concentration; Imipramine; Immunoenzyme Techniques; Mesencephalon; Microscopy, Electron; Neurons; Phencyclidine; Psychotropic Drugs; Rats; Serotonin; Tyramine | 1990 |
Vascular responses of ophthalmic arteries to exogenous and endogenous norepinephrine.
Topics: Animals; Calcium; Cocaine; Diltiazem; Dogs; Egtazic Acid; Electric Stimulation; Hydrocortisone; Imipramine; In Vitro Techniques; Norepinephrine; Ophthalmic Artery; Perfusion; Potassium Chloride; Tyramine; Vasoconstriction | 1989 |
Chronic imipramine does not block cocaine-induced increases in brain stimulation reward.
Topics: Animals; Brain; Cocaine; Drug Interactions; Electric Stimulation; Imipramine; Male; Rats; Rats, Inbred Strains; Reward; Self Stimulation | 1989 |
Mechanisms of extraneuronal serotonin uptake in the rat aorta.
Topics: Animals; Aorta; Cocaine; Cold Temperature; Corticosterone; Desipramine; Hydroxydopamines; Imipramine; Kinetics; Male; Neurons; Norepinephrine; Oxidopamine; Pargyline; Rats; Rats, Inbred Strains; Serotonin | 1986 |
The interactive effects of cocaine and imipramine on self-stimulation train-duration thresholds.
Topics: Animals; Cocaine; Drug Synergism; Imipramine; Male; Rats; Rats, Inbred Strains; Self Stimulation; Time Factors | 1988 |
[Pharmacologic studies of a tetrahydroxazine derivative].
Topics: Amphetamine; Anesthetics, Local; Animals; Appetite; Appetite Depressants; Behavior, Animal; Cocaine; Haloperidol; Imipramine; Morpholines; Motor Activity; Phenmetrazine; Propiophenones; Rats; Rats, Inbred Strains; Reserpine | 1988 |
The cardiac effects of cocaine and certain antihistamines and antidepressants.
Topics: Animals; Antidepressive Agents; Brompheniramine; Chlorpheniramine; Cocaine; Desipramine; Guinea Pigs; Heart; Histamine H1 Antagonists; Imipramine; Nerve Endings; Norepinephrine; Tripelennamine; Triprolidine; Tyramine | 1973 |
[Catecholamines and adrenergic receptors].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Amphetamine; Catecholamines; Cocaine; Dibenzocycloheptenes; Humans; Imipramine | 1974 |
[The effect of drugs on the amine storage function of blood platelets].
Topics: Anesthetics, Local; Animals; Biological Transport; Blood Platelets; Catecholamines; Cell Membrane Permeability; Chlorpromazine; Cocaine; Desipramine; Histamine H1 Antagonists; Imipramine; Phenothiazines; Rabbits; Reserpine; Serotonin; Sympathomimetics; Tryptamines | 1969 |
The effects of stimulants and depressants on cocaine self-administration behavior in the rhesus monkey.
Topics: Animals; Cocaine; Exploratory Behavior; Grooming; Haplorhini; Imipramine; Locomotion; Macaca; Male; Morphine; Motor Activity; Pentobarbital; Phenmetrazine; Self Medication; Trifluoperazine | 1973 |
A comparison of chlorpromazine, imipramine, morphine and d-amphetamine self-administration in cocaine-dependent rhesus monkeys.
Topics: Animals; Behavior, Animal; Chlorpromazine; Cocaine; Dextroamphetamine; Dose-Response Relationship, Drug; Haplorhini; Humans; Imipramine; Macaca; Morphine; Self Stimulation; Substance-Related Disorders | 1973 |
The role of the sympathetic nervous system in mediating the action of analgesic drugs on the lens.
Topics: Amitriptyline; Amphetamine; Animals; Bretylium Compounds; Cocaine; Dopamine; Ephedrine; Epinephrine; Guanethidine; Imipramine; Iproniazid; Lens, Crystalline; Metaraminol; Methadone; Mice; Nialamide; Norepinephrine; Phenylephrine; Reserpine; Sympathetic Nervous System; Synephrine | 1968 |
The termination of action of catecholamines in the isolated venous tissue of the dog.
Topics: Animals; Autoradiography; Cocaine; Dogs; Drug Antagonism; Drug Synergism; Epinephrine; Histocytochemistry; Imipramine; Immersion; In Vitro Techniques; Iproniazid; Monoamine Oxidase Inhibitors; Neural Conduction; Norepinephrine; Oils; Perfusion; Saphenous Vein; Tritium; Veins | 1971 |
Uptake of 5-hydroxytryptamine by mast cell granules in vitro.
Topics: Adenosine Triphosphate; Amines; Amitriptyline; Animals; Chlorides; Chlorpromazine; Cocaine; Culture Media; Cyanides; Cytoplasmic Granules; Dinitrophenols; Guanethidine; Hot Temperature; Hydrazines; Imipramine; In Vitro Techniques; Inclusion Bodies; Mast Cells; Microscopy, Electron; Osmolar Concentration; Ouabain; Peritoneum; Prenylamine; Rats; Reserpine; Serotonin | 1971 |
Some structural considerations of the reactivity of vascular smooth muscle.
Topics: Angiotensin II; Animals; Aorta; Blood Vessels; Bretylium Compounds; Catecholamines; Cocaine; Diffusion; Electric Stimulation; Imipramine; Methods; Muscle Contraction; Muscle, Smooth; Neural Conduction; Neuroeffector Junction; Nicotine; Norepinephrine; Pulmonary Artery; Rabbits; Serotonin; Tritium; Tyramine | 1969 |
Effect of various procedures on the repletion of cardiac catecholamine stores after tyramine.
Topics: Adrenal Medulla; Animals; Bretylium Compounds; Cocaine; Disulfiram; Enzymes; Hydrazines; Imipramine; In Vitro Techniques; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; Radiometry; Rats; Tritium; Tyramine | 1965 |
In vivo inhibition of 3H-noradrenaline uptake by mouse brain slices in vitro.
Topics: Amitriptyline; Amphetamine; Animals; Brain; Chlordiazepoxide; Chlorpromazine; Cocaine; Desipramine; Imipramine; In Vitro Techniques; Mice; Norepinephrine; Tritium | 1966 |
Antagonism of the adrenergic neurone blocking action of guanethidine by certain antidepressant and antihistamine drugs.
Topics: Animals; Blood Pressure; Carotid Arteries; Cocaine; Dextroamphetamine; Dogs; Drug Antagonism; Guanethidine; Histamine H1 Antagonists; Hydrazines; Imipramine; Methamphetamine; Methylphenidate; Promethazine | 1966 |
Potentiation of the anticonvulsant action of acetazolamide.
Topics: Acetazolamide; Amphetamine; Animals; Anticonvulsants; Caffeine; Cocaine; Desipramine; Drug Synergism; Electric Stimulation; Electroshock; Ephedrine; Histamine H1 Antagonists; Imipramine; Isoproterenol; Male; Metaraminol; Mice; Morphine; Phenethylamines; Quaternary Ammonium Compounds; Seizures; Stress, Physiological; Tranylcypromine; Tyramine | 1966 |
Mechanisms of sympathomimetic effects of dichloroisoproterenol: comparison with tyramine, nicotine and norepinephrine.
Topics: Animals; Atropine; Cocaine; Diaphragm; Drug Antagonism; Ganglionic Blockers; Guanidines; Heart; Heart Atria; Hexamethonium Compounds; Imipramine; In Vitro Techniques; Iproniazid; Isoproterenol; Morphine; Nicotine; Norepinephrine; Pentolinium Tartrate; Phenoxybenzamine; Propranolol; Rats; Sympatholytics; Tranylcypromine; Tyramine | 1967 |
Adamantanamines and their derivatives as sensitizing agents for 5-hydroxytryptamine-induced contraction of smooth muscle.
Topics: Amantadine; Animals; Cocaine; Dibenzylchlorethamine; Imipramine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neuraminidase; Propylamines; Rats; Sensory Receptor Cells; Serotonin | 1967 |
Frequency-dependent potentiation by various drugs of the chronotropic response of isolated cat atria to sympathetic nerve stimulation.
Topics: Animals; Cats; Cocaine; Cycloparaffins; Electric Stimulation; Heart Atria; Hydrazines; Imipramine; In Vitro Techniques; Ketones; Methylphenidate; Monoamine Oxidase; Norepinephrine; Phenoxybenzamine; Transferases; Tritium | 1967 |
Norepinephrine metabolism and drugs used in the affective disorders: a possible mechanism of action.
Topics: Animals; Antidepressive Agents; Bipolar Disorder; Brain; Central Nervous System Stimulants; Chlorpromazine; Cocaine; Depression; Desipramine; Emotions; Humans; Imipramine; Lithium; Monoamine Oxidase Inhibitors; Norepinephrine; Normetanephrine; Rats; Reserpine; Tranquilizing Agents; Tritium | 1967 |
The effect of imipramine, cocaine and neostigmine on the hyperglycaemic response to noradrenaline and adrenaline.
Topics: Atropine; Blood Glucose; Blood Pressure; Catecholamines; Cocaine; Imipramine; Injections, Subcutaneous; Neostigmine | 1968 |
The influences of drugs on the uptake of 5-hydroxytryptamine by synaptic vesicles of rabbit brain stem.
Topics: Animals; Brain Stem; Cocaine; Desipramine; Imipramine; Male; Nerve Endings; Rabbits; Reserpine; Serotonin | 1968 |
The effect of antidepressant drugs and cocaine on the self-stimulation in rats.
Topics: Amitriptyline; Animals; Cocaine; Hydrazines; Imipramine; Rats; Self Stimulation; Tranylcypromine | 1968 |
The effect of some psychopharmacological agents, pronethalol and atropine on the vasodilatation of the eye bulb of rabbit due to local application of reserpine and tolazoline.
Topics: Amphetamine; Animals; Atropine; Blood Vessels; Cocaine; Conjunctiva; Depression, Chemical; Ethanolamines; Imipramine; Nialamide; Rabbits; Reserpine; Stimulation, Chemical; Tolazoline; Vasodilator Agents; Vasomotor System | 1968 |
The evaluation of central nervous system stimulants in a new laboratory test for antidepressants.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Blood Pressure; Central Nervous System Stimulants; Cocaine; Dextroamphetamine; Dogs; Drug Synergism; Imipramine; Yohimbine | 1969 |
A use of the isomeric ratio as a criterion to differentiate adrenergic receptors.
Topics: Animals; Blood Pressure; Cats; Cocaine; Imipramine; Male; Nictitating Membrane; Norepinephrine; Rats; Receptors, Drug; Spleen; Stereoisomerism; Vas Deferens | 1969 |
Factors involved in maintenance of cardiac catecholamine content: relative importance of synthesis and re-uptake.
Topics: Adrenal Medulla; Animals; Catecholamines; Cocaine; Cold Temperature; Hydrazines; Imipramine; Male; Myocardium; Norepinephrine; Pargyline; Phenoxybenzamine; Rats; Sympathetic Nervous System; Tritium | 1969 |
Is epinephrine reversal a phenomenon purely of -adrenergic block?
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Blood Pressure; Cats; Cocaine; Drug Antagonism; Epinephrine; Ergotamine; Female; Guinea Pigs; Imipramine; In Vitro Techniques; Male; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Phentolamine; Rabbits; Rats; Receptors, Adrenergic; Uterus; Vas Deferens | 1970 |
Behavioural effects od d-amphetamine alone and in combination with antidepressants, antihistamines or other psychotropic drugs in young chicks.
Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Chickens; Chlorpheniramine; Cocaine; Desipramine; Dextroamphetamine; Diphenhydramine; Drug Antagonism; Drug Interactions; Histamine H1 Antagonists; Imipramine; Male; Nortriptyline; Promethazine | 1972 |
Site and mechanism of uptake of 3H--norepinephrine by isolated perfused rat lungs.
Topics: Animals; Autoradiography; Cocaine; Deamination; Endothelium; Imipramine; Lung; Metaraminol; Methylation; Microscopy, Electron; Muscle, Smooth; Neurons; Norepinephrine; Normetanephrine; Ouabain; Potassium; Rats; Serotonin; Sodium; Temperature; Tritium | 1974 |
d-amphetamine and the release of 3H-norepinephrine from synaptosomes.
Topics: Animals; Brain; Brain Stem; Cerebral Cortex; Cocaine; Dextroamphetamine; Hypothalamus; Imipramine; In Vitro Techniques; Male; Norepinephrine; Rats; Synaptosomes; Tritium | 1974 |
[Role of the lungs in the inactivation of serotonin].
Topics: Animals; Body Temperature; Cocaine; Cyanides; Imipramine; Iodoacetates; Lung; Lysergic Acid Diethylamide; Monoamine Oxidase Inhibitors; Morphine; Potassium; Rats; Serotonin; Time Factors | 1974 |
Supersensitivity to alpha and beta effects of adrenaline induced by cocaine.
Topics: Animals; Cocaine; Dibenzylchlorethamine; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; Imipramine; In Vitro Techniques; Male; Muscle Contraction; Propranolol; Rats; Receptors, Adrenergic; Stomach; Tolazoline; Vas Deferens | 1974 |
Incorporation of imipramine into isolated rat peritoneal mast cells in vitro.
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Binding Sites; Calcium; Cell Membrane Permeability; Chlorpromazine; Cocaine; Depression, Chemical; Desipramine; Dibenzazepines; Female; Guanethidine; Hydrogen-Ion Concentration; Imipramine; Leukocytes; Male; Mast Cells; Nortriptyline; Rats; Receptors, Drug; Reserpine; Serotonin; Temperature | 1974 |
Mechanisms of catecholamine inactivation by the endocrine pancreas.
Topics: Animals; Catechol O-Methyltransferase Inhibitors; Catecholamines; Cells, Cultured; Cocaine; Cricetinae; Culture Media; Dopamine; Drug Synergism; Imipramine; Insulin; Insulin Secretion; Islets of Langerhans; Levodopa; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nortriptyline; Pargyline; Rabbits; Rats; Species Specificity; Stimulation, Chemical; Tranylcypromine | 1974 |
Uptake of desipramine by the rat vas deferens.
Topics: Animals; Cocaine; Denervation; Desipramine; Dinitrophenols; Dose-Response Relationship, Drug; Drug Synergism; Imipramine; In Vitro Techniques; Iodoacetates; Kinetics; Male; Norepinephrine; Ouabain; Rats; Temperature; Time Factors; Vas Deferens | 1972 |
Pharmacological analysis of norepinephrine and 5-hydroxytryptamine removal from the pulmonary circulation: differentiation of uptake sites for each amine.
Topics: Aminophylline; Animals; Binding Sites; Binding, Competitive; Cocaine; Hydroxydopamines; Imipramine; Lung; Norepinephrine; Normetanephrine; Pargyline; Perfusion; Phenoxybenzamine; Phentolamine; Propranolol; Rabbits; Serotonin; Vasoconstrictor Agents | 1974 |
Effect of adrenergic drugs on pulmonary responses to high-pressure oxygen.
Topics: Animals; Atmospheric Pressure; Catecholamines; Cocaine; Drug Combinations; Hemodynamics; Imipramine; Lung; Male; Oxygen; Phentolamine; Propranolol; Pulmonary Edema; Rats; Reserpine; Tyramine | 1974 |
Behavioural and biochemical comparison of amphetamine derivatives, cocaine, benztropine and tricyclic anti-depressant drugs.
Topics: Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Benztropine; Brain; Brain Chemistry; Cocaine; Desipramine; Dopamine; Imipramine; Iproniazid; Male; Motor Activity; Nialamide; Norepinephrine; Normetanephrine; Parasympatholytics; Rats; Rats, Inbred Strains; Stimulation, Chemical; Tropanes; Tyramine | 1972 |
Accumulation of 14 C-imipramine in isolated perfused rat lungs.
Topics: Animals; Binding Sites; Binding, Competitive; Biological Transport; Carbon Isotopes; Cell Membrane; Chlorpromazine; Chromatography; Cocaine; Creatinine; Imipramine; In Vitro Techniques; Iproniazid; Lung; Male; Perfusion; Rats; Serotonin; Time Factors | 1972 |
Uptake, metabolism and efflux of 14 C-5-hydroxytryptamine in isolated perfused rat lungs.
Topics: Anaerobiosis; Animals; Biological Transport; Carbon Isotopes; Chlorpromazine; Chromatography, Thin Layer; Cocaine; Glucose; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Iproniazid; Lung; Male; Norepinephrine; Osmolar Concentration; Ouabain; Perfusion; Potassium; Rats; Reserpine; Serotonin; Sodium; Tryptamines | 1972 |
Pharmacological properties of dehydroascorbic acid and ascorbic acid. Effects on the central and peripheral nervous systems in experimental animals.
Topics: Acetylcholine; Adrenal Glands; Adrenalectomy; Animals; Ascorbic Acid; Blood Pressure; Brain; Bretylium Compounds; Carbon Isotopes; Cats; Central Nervous System; Chromatography; Cocaine; Cordotomy; Dopamine; Epinephrine; Ergotamine; Female; Guanethidine; Hexamethonium Compounds; Imipramine; Male; Mice; Motor Activity; Myocardium; Neuromuscular Junction; Nictitating Membrane; Norepinephrine; Peripheral Nerves; Phenoxybenzamine; Propranolol; Rabbits; Reserpine; Salivation; Tetraethylammonium Compounds | 1970 |
5-hydroxytryptamine uptake by rat brain in vitro.
Topics: 5-Hydroxytryptophan; Adenosine Triphosphate; Animals; Brain; Carbon Isotopes; Chlorpromazine; Cocaine; Desipramine; Dinitrophenols; Dopamine; Glucose; Imipramine; In Vitro Techniques; Iodoacetates; Iproniazid; Male; Norepinephrine; Ouabain; Rats; Reserpine; Serotonin; Serotonin Antagonists; Tryptamines | 1967 |
Effect of some drugs on the uptake of monoamines and their precursors in the mouse Paneth cells.
Topics: 5-Hydroxytryptophan; Amines; Amitriptyline; Amphetamine; Animals; Binding Sites; Catecholamines; Chlorpromazine; Cocaine; Colon; Cytoplasmic Granules; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Duodenum; Female; Guanethidine; Ileum; Imipramine; Jejunum; Male; Methyltyrosines; Mice; Microscopy, Fluorescence; Nortriptyline; Pargyline; Peptide Biosynthesis; Promazine; Reserpine; Serotonin; Tyrosine | 1971 |
Studies in vitro of amine uptake mechanisms in heart.
Topics: Animals; Cocaine; Cold Temperature; Ganglia, Autonomic; Guanethidine; Hot Temperature; Imipramine; Immune Sera; In Vitro Techniques; Metaraminol; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; Octopamine; Ouabain; Rabbits; Rats; Reserpine; Tetrabenazine; Tyramine | 1966 |
Inhibition of the uptake of tritiated 5-hydroxytryptamine in brain tissue.
Topics: Amitriptyline; Animals; Antidepressive Agents; Antimetabolites; Brain; Cocaine; Desipramine; Imipramine; In Vitro Techniques; Mice; Nortriptyline; Reserpine; Serotonin; Tritium; Tryptamines | 1969 |
Evidence for biogenic amine receptors in toad sciatic nerves.
Topics: Animals; Anura; Axons; Chlorpromazine; Chlorzoxazone; Cocaine; Drug Antagonism; Epinephrine; Histamine; Imipramine; Lysergic Acid Diethylamide; Membranes; Neural Conduction; Nicotine; Nicotinic Acids; Pentolinium Tartrate; Potassium Chloride; Procaine; Sciatic Nerve; Sensory Receptor Cells; Serotonin; Sodium; Time Factors | 1969 |
The influence of harmaline and monoamines on body temperature of rats after intracisternal injection.
Topics: Alkaloids; Animals; Body Temperature; Cocaine; Depression, Chemical; Dopamine; Imipramine; Indoles; Injections; Nerve Endings; Norepinephrine; Rats; Serotonin | 1969 |
[Thymoleptics and lipolysis].
Topics: Adipose Tissue; Amitriptyline; Animals; Antidepressive Agents; Cocaine; Depression, Chemical; Desipramine; Dibenzazepines; Fatty Acids, Nonesterified; Imipramine; In Vitro Techniques; Lipid Metabolism; Male; Norepinephrine; Nortriptyline; Photometry; Rats; Stimulation, Chemical; Tranquilizing Agents | 1969 |
Effect of noradrenaline, dopamine and 5-hydroxytryptamine on body temperature in the rat after intracisternal administration.
Topics: Animals; Body Temperature; Body Temperature Regulation; Cisterna Magna; Cocaine; Dopamine; Hypothalamus; Hypothermia; Imipramine; Male; Norepinephrine; Rats; Serotonin | 1970 |
Factors affecting the contractile responses of the rat vas deferens to cocaine and tetracaine.
Topics: Animals; Cocaine; Desipramine; Electric Stimulation; Glucose; Guanethidine; Hydrogen-Ion Concentration; Imipramine; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Oxygen; Rats; Reserpine; Temperature; Tetracaine; Tyramine; Vas Deferens | 1970 |
[The significance of noradrenaline in the development of spontaneous contractile activity in smooth muscle].
Topics: Animals; Cocaine; Dogs; Guanethidine; Imipramine; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Sympathetic Nervous System; Synaptic Vesicles | 1970 |
Inhibition of renal tubular transport of catecholamines by cocaine: an organic base mechanism.
Topics: Aminohippuric Acids; Animals; Biological Transport, Active; Carbon Isotopes; Catecholamines; Chickens; Cocaine; Desipramine; Dibenzocycloheptenes; Dopamine; Epinephrine; Imipramine; Kidney Tubules; Models, Biological; Norepinephrine; Phenethylamines; Phenylacetates; Quaternary Ammonium Compounds; Renal Artery; Tyramine | 1970 |
Uptake and release of norepinephrine by rat brain tissue fractions prepared by ultrafiltration.
Topics: Amantadine; Animals; Brain; Catecholamines; Cocaine; Cytoplasmic Granules; Dialysis; Filtration; Imipramine; Monoamine Oxidase; Nerve Endings; Norepinephrine; Ouabain; Phenethylamines; Potassium; Rats; Serotonin; Synapses; Synaptic Vesicles; Tritium | 1971 |
Concentrations of desipramine in the vas deferens and potentiation of noradrenaline response.
Topics: Animals; Cocaine; Denervation; Desipramine; Drug Synergism; Imipramine; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Ouabain; Rats; Temperature; Tritium; Vas Deferens | 1971 |
[Pharmacology of diphenylalkyl-derivatives. IV. Pharmacology of a noradrenaline increasing effect of dephenylpropylamine-amine-derivatives].
Topics: Adrenalectomy; Amphetamine; Anesthetics, Local; Animals; Blepharoptosis; Blood Pressure; Cardiovascular System; Cats; Central Nervous System; Cocaine; Drug Synergism; Epinephrine; Female; Guinea Pigs; Imipramine; In Vitro Techniques; Male; Mice; Norepinephrine; Propylamines; Rats; Reserpine; Sympathetic Nervous System; Tetrabenazine; Tyramine; Vas Deferens; Vasopressins | 1967 |
Inhibition by drugs of the accumulation in vitro of 5-hydroxytryptamine in guinea-pig vas deferens.
Topics: Amitriptyline; Animals; Antidepressive Agents; Carbon Isotopes; Chlorpromazine; Cocaine; Desipramine; Guinea Pigs; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Male; Serotonin; Vas Deferens | 1968 |
A new type of drug enhancement: increased maximum response to cumulative noradrenaline in the isolated rat vas deferens.
Topics: Amitriptyline; Animals; Cocaine; Desipramine; Drug Synergism; Imipramine; Male; Muscle Contraction; Norepinephrine; Phentolamine; Rats; Vas Deferens | 1968 |
Enhancement of H3-norepinephrine accumulation in rat vas deferens by cocaine, imipramine, and desmethylimipramine.
Topics: Animals; Cocaine; Desipramine; Guanethidine; Imipramine; Male; Metaraminol; Myocardium; Norepinephrine; Rats; Reserpine; Stimulation, Chemical; Tritium; Vas Deferens | 1968 |
Potentiation of morphine analgesia by cocaine in mice.
Topics: Amphetamine; Analgesia; Animals; Cocaine; Dibucaine; Drug Synergism; Female; Imipramine; Lidocaine; Male; Mice; Morphine; Norepinephrine; Phentolamine; Procaine; Rats; Reserpine | 1968 |
The effects of drugs inhibiting catecholamine uptake on tyramine and noradrenaline-induced contractions of the isolated rat vas deferens.
Topics: Animals; Catecholamines; Cocaine; Drug Antagonism; Imipramine; Male; Muscle Contraction; Norepinephrine; Rats; Tritium; Tyramine; Vas Deferens | 1968 |
The effect of cocaine and imipramine on tyramine-induced release of noradrenaline-3H from the rat vas deferens in vitro.
Topics: Animals; Cocaine; Imipramine; In Vitro Techniques; Male; Norepinephrine; Rats; Receptors, Drug; Tritium; Tyramine; Vas Deferens | 1969 |
Anticholinergic activities of imipramine and methylphenidate.
Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Carbamates; Cats; Cocaine; Female; Imipramine; Male; Methylphenidate; Quaternary Ammonium Compounds; Salivation | 1969 |
Adrenaline reversal by CIBA 1002-Go.
Topics: Acetylcholine; Animals; Blood Pressure; Cats; Cocaine; Depression, Chemical; Dogs; Drug Synergism; Epinephrine; Female; Heart Rate; Hexamethonium Compounds; Imipramine; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Norepinephrine; Phenoxybenzamine; Piperidines; Propranolol; Pyrazoles; Rabbits; Rats; Receptors, Drug; Stimulation, Chemical; Uterus | 1969 |
Thin-layer chromatographic detection of barbiturates, narcotics, and amphetamines in urine of patients receiving psychotropic drugs.
Topics: Amphetamine; Barbiturates; Chlorpromazine; Chromatography, Thin Layer; Cocaine; Codeine; Humans; Imipramine; Ion Exchange Resins; Meperidine; Methadone; Morphine; Narcotics; Quinine; Thioridazine; Trifluoperazine | 1969 |
The accumulation of C14-serotonin in the guinea-pig vas deferens.
Topics: Animals; Biological Transport, Active; Carbon Isotopes; Cocaine; Desipramine; Dopamine; Guinea Pigs; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Kinetics; Male; Microsomes; Mitochondria, Muscle; Norepinephrine; Ouabain; Reserpine; Serotonin; Temperature; Time Factors; Tryptamines; Tyramine; Vas Deferens | 1969 |
The action of protriptyline on peripheral autonomic function.
Topics: Animals; Antidepressive Agents; Autonomic Nervous System; Blood Pressure; Cats; Cocaine; Dogs; Epinephrine; Guanethidine; Guinea Pigs; Heart; Heart Rate; Imipramine; In Vitro Techniques; Myocardium; Nictitating Membrane; Norepinephrine; Tyramine | 1965 |
Effect of electroshock and antidepressant drugs on cerebrovascular permeability to cocaine in the rat.
Topics: Amitriptyline; Animals; Antidepressive Agents; Blood-Brain Barrier; Chlorpromazine; Cocaine; Electric Stimulation; Electroshock; Female; Imipramine; Injections, Intravenous; Nortriptyline; Rats | 1966 |
[Mechanism of the inhibiting effect of atypical antidepressants and psychostimulants on the synaptosomal uptake of monoamines].
Topics: Amphetamine; Animals; Antidepressive Agents; Brompheniramine; Cerebral Cortex; Cocaine; Dopamine; Imipramine; Norepinephrine; Rats; Serotonin; Synaptosomes; Viloxazine; Zimeldine | 1983 |
Pharmacological dissection of receptor-associated and voltage-sensitive ionic channels involved in catecholamine release.
Topics: Acetylcholine; Adrenal Medulla; Animals; Catecholamines; Cattle; Cocaine; Electrolytes; Ethers; Imipramine; Ion Channels; Ionomycin; Membrane Potentials; Nicotine; Norepinephrine; Receptors, Cholinergic; Receptors, Nicotinic; Synaptic Transmission; Tetrodotoxin; Veratridine | 1983 |
Electrophysiological effects of cocaine in the rat hippocampus in vitro.
Topics: Animals; Cocaine; Culture Techniques; Desipramine; Dose-Response Relationship, Drug; Evoked Potentials; Hippocampus; Imipramine; Male; Norepinephrine; Rats; Rats, Inbred Strains; Synaptic Transmission | 1984 |
Binding of imipramine and cocaine to a model lipid membrane: comparison with binding to brain membranes.
Topics: Animals; Cerebral Cortex; Chemical Phenomena; Chemistry; Cocaine; Imipramine; Liposomes; Male; Mice; Mice, Inbred BALB C; Phosphatidylcholines; Receptors, Drug | 1984 |
Uptake of [3H]-nicotine and [3H]-noradrenaline by cultured chromaffin cells.
Topics: Adrenal Medulla; Animals; Cattle; Cell Membrane; Cells, Cultured; Chromaffin System; Cocaine; Imipramine; Mecamylamine; Nicotine; Norepinephrine; Tetracaine | 1984 |
Similarities and differences between high-affinity binding sites for cocaine and imipramine in mouse cerebral cortex.
Topics: Animals; Binding Sites; Cerebral Cortex; Cocaine; Dithiothreitol; Ethylmaleimide; Imipramine; Male; Mice; Mice, Inbred BALB C; Neurons; Phospholipases A; Phospholipases A2; Serotonin; Trypsin | 1984 |
Effect of uptake blockers on 5-hydroxytryptamine & noradrenaline induced responses on rat anococcygeus muscle.
Topics: Animals; Cocaine; Dexamethasone; Imipramine; Male; Muscles; Norepinephrine; Phentolamine; Rats; Rats, Inbred Strains; Serotonin | 1982 |
[Comparison of the effects of several psychotropic drugs by gross behavioral observation on rhesus monkeys].
Topics: Amphetamines; Animals; Barbital; Behavior, Animal; Chlorpromazine; Cocaine; Diazepam; Female; Imipramine; Lysergic Acid Diethylamide; Macaca mulatta; Male; Morphine; Psychotropic Drugs | 1981 |
Repeated antidepressant treatments induce a long-lasting dopamine autoreceptor subsensitivity: is daily treatment necessary for clinical efficacy? [proceedings].
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cocaine; Death, Sudden; Electrophysiology; Imipramine; Iprindole; Receptors, Dopamine; Statistics as Topic; Substantia Nigra; Time Factors | 1981 |
Effect of imipramine on high potassium evoked 3H-dopamine release in the rat striatum.
Topics: Animals; Calcium; Cocaine; Corpus Striatum; Dopamine; Imipramine; Male; Nomifensine; Potassium; Rats | 1981 |
Pulmonary clearance of [14C]-5-hydroxytryptamine and [3H]norepinephrine in vivo: effects of pretreatment with imipramine or cocaine.
Topics: Animals; Cocaine; Dextrans; Imipramine; Indocyanine Green; Lung; Male; Metabolic Clearance Rate; Norepinephrine; Rabbits; Serotonin | 1980 |
A comparison of the effects of d-amphetamine, cocaine, imipramine and pentobarbital on local and overall rates of responding maintained under a four-component multiple fixed-interval schedule.
Topics: Animals; Cocaine; Columbidae; Conditioning, Operant; Dextroamphetamine; Imipramine; Male; Pentobarbital; Reinforcement Schedule; Stimulation, Chemical | 1980 |
Intraneuronal site of action for imipramine in rat striatal slices.
Topics: Animals; Cocaine; Corpus Striatum; Dopamine; Imipramine; In Vitro Techniques; Kinetics; Male; Neurons; Potassium; Rats | 1980 |
Regulation of the human serotonin transporter by interleukin-1 beta.
Topics: Biological Transport; Carrier Proteins; Cell Line; Cell Membrane; Choriocarcinoma; Cocaine; Cyclic AMP; Cyclic GMP; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; Imipramine; Interleukin-1; Iodine Radioisotopes; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Pregnancy; RNA, Messenger; Serotonin; Serotonin Plasma Membrane Transport Proteins; Time Factors; Tumor Cells, Cultured; Uterine Neoplasms | 1995 |
Chimeric human and rat serotonin transporters reveal domains involved in recognition of transporter ligands.
Topics: Amino Acid Sequence; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Binding Sites; Carrier Proteins; Cocaine; Dextroamphetamine; HeLa Cells; Humans; Imipramine; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Nerve Tissue Proteins; Rats; Recombinant Fusion Proteins; Serotonin; Serotonin Plasma Membrane Transport Proteins; Species Specificity; Structure-Activity Relationship | 1994 |
Ligand binding to the serotonin transporter: equilibria, kinetics, and ion dependence.
Topics: Blood Platelets; Carrier Proteins; Chlorides; Cocaine; Dose-Response Relationship, Drug; Humans; Imipramine; Kinetics; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Binding; Regression Analysis; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sodium | 1994 |
Effect on pressor and vascular responsiveness in rabbits of drugs that decrease norepinephrine uptake.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Cardiac Output; Cocaine; Dose-Response Relationship, Drug; Heart Rate; Imipramine; Male; Norepinephrine; Rabbits; Vascular Resistance | 1994 |
The discriminative stimulus effects of methamphetamine in pigeons.
Topics: Animals; Behavior, Animal; Clonidine; Cocaine; Columbidae; Conditioning, Operant; Discrimination, Psychological; Dopamine; Dose-Response Relationship, Drug; Imipramine; Injections, Intramuscular; Male; Methamphetamine; Neurotransmitter Agents | 1995 |
Phenomenology and neurobiology of cocaine withdrawal: are they related?
Topics: Adult; Affect; Binding, Competitive; Cocaine; Female; Humans; Imipramine; Male; Psychiatric Status Rating Scales; Radioligand Assay; Substance Withdrawal Syndrome | 1995 |
Changes in serotonin and norepinephrine uptake sites after chronic cocaine: pre- vs. post-withdrawal effects.
Topics: Administration, Oral; Animals; Autoradiography; Biological Transport; Brain; Carrier Proteins; Cocaine; Drug Administration Schedule; Female; Fluoxetine; Imipramine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Organ Specificity; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Substance Withdrawal Syndrome; Substance-Related Disorders; Symporters; Time Factors; Tritium | 1996 |
Pharmacotherapy of schizophrenia patients with comorbid substance abuse.
Topics: Alcoholism; Antipsychotic Agents; Cocaine; Flupenthixol; Humans; Imipramine; Marijuana Abuse; Opioid-Related Disorders; Schizophrenia; Self Medication; Substance-Related Disorders; Tobacco Use Disorder | 1997 |
[3H]substrate- and cell-specific effects of uptake inhibitors on human dopamine and serotonin transporter-mediated efflux.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Calcium; Carrier Proteins; Cloning, Molecular; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Glioma; Half-Life; Humans; Imipramine; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Nerve Tissue Proteins; Rats; Recombinant Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Transfection; Tritium | 1998 |
Protection of neuronal uptake-1 inhibitors in ischemic and anoxic hearts by norepinephrine-dependent and -independent mechanisms.
Topics: Adrenergic Uptake Inhibitors; Animals; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Drug Interactions; Hypoxia; Imipramine; Inositol 1,4,5-Trisphosphate; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Norepinephrine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Ventricular Fibrillation | 1998 |
Pharmacological profile of neuroleptics at human monoamine transporters.
Topics: Antipsychotic Agents; Carrier Proteins; Cell Line; Chlorpromazine; Cocaine; Dibenzazepines; Dibenzothiepins; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Humans; Imipramine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Pimozide; Piperazines; Protein Binding; Radioligand Assay; Recombinant Fusion Proteins; Serotonin Plasma Membrane Transport Proteins; Symporters; Thiazoles; Triflupromazine; Tritium | 1999 |
A chronic stress that impairs reactivity in rats also decreases dopaminergic transmission in the nucleus accumbens: a microdialysis study.
Topics: Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Chronic Disease; Cocaine; Dextroamphetamine; Dopamine; Dopamine Uptake Inhibitors; Escape Reaction; Imipramine; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reference Values; Stress, Physiological; Synaptic Transmission | 1999 |
Transmembrane domain I contributes to the permeation pathway for serotonin and ions in the serotonin transporter.
Topics: Adrenergic Uptake Inhibitors; Alkaloids; Amino Acid Substitution; Animals; Aspartic Acid; Biological Transport; Calcium-Binding Proteins; Calnexin; Carrier Proteins; Cocaine; COS Cells; HeLa Cells; Humans; Imipramine; Indole Alkaloids; Intracellular Membranes; Iodine Radioisotopes; Ion Channel Gating; Membrane Glycoproteins; Membrane Potentials; Membrane Transport Proteins; Molecular Sequence Data; N,N-Dimethyltryptamine; Nerve Tissue Proteins; Oocytes; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Serotonin; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Sodium Chloride; Transfection; Tritium; Xenopus | 1999 |
Antidepressant drugs inhibit glucocorticoid receptor-mediated gene transcription - a possible mechanism.
Topics: Amantadine; Animals; Antidepressive Agents; Cell Line, Transformed; Chloramphenicol O-Acetyltransferase; Cocaine; Corticosterone; Cyclic AMP; Cyclic GMP; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Estrenes; Gene Expression Regulation; Imipramine; Lithium Chloride; Memantine; Mifepristone; Protein Kinase Inhibitors; Pyrrolidinones; Receptors, Glucocorticoid; Receptors, Steroid; Sulfonamides; Tamoxifen; Thionucleotides; Time Factors; Transcription, Genetic; Type C Phospholipases | 2000 |
THE UPTAKE AND BINDING OF CIRCULATING SEROTONIN AND THE EFFECT OF DRUGS.
Topics: Amphetamine; Amphetamines; Carbon Isotopes; Chlorpromazine; Cocaine; Guanethidine; Hydrazines; Imipramine; Indoles; Lysergic Acid Diethylamide; Metabolism; Mice; Pharmacology; Rats; Research; Reserpine; Serotonin; Tyramine | 1963 |
BEHAVIORAL EFFECTS OF INTERACTING IMIPRAMINE AND OTHER DRUGS WITH D-AMPHETAMINE, COCAINE, AND TETRABENAZINE.
Topics: Amitriptyline; Atropine; Avoidance Learning; Chlorpromazine; Cocaine; Desipramine; Dextroamphetamine; Guanethidine; Imipramine; Iproniazid; Isocarboxazid; Methylphenidate; Parasympatholytics; Pharmacology; Piperidines; Promazine; Promethazine; Rats; Research; Scopolamine; Tetrabenazine; Trihexyphenidyl; Tyramine | 1964 |
ANTAGONISM OF CERTAIN EFFECTS OF CATECHOLAMINE-DEPLETING AGENTS BY ANTIDEPRESSANT AND RELATED DRUGS.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Catecholamines; Chlorpromazine; Cocaine; Desipramine; Dogs; Dopamine; Electric Stimulation; Electrophysiology; Guanethidine; Imipramine; Metaraminol; Methylphenidate; Mice; Myocardium; Nictitating Membrane; Norepinephrine; Pharmacology; Piperidines; Promazine; Research; Reserpine; Tripelennamine; Tyrosine | 1964 |
A STUDY OF THE MECHANISMS OF THE MODIFYING ACTIONS OF COCAINE, EPHEDRINE AND IMIPRAMINE ON THE CARDIOVASCULAR RESPONSE TO NOREPINEPHRINE AND EPINEPHRINE.
Topics: Animals; Blood Pressure; Cardiovascular System; Cocaine; Dogs; Ephedrine; Epinephrine; Imipramine; Injections; Injections, Intra-Arterial; Injections, Intravenous; Norepinephrine; Pharmacology; Research | 1964 |
THE EFFECTS OF DRUGS ON THE UPTAKE OF AMINES BY MAST CELLS.
Topics: Amines; Animals; Chlorpromazine; Cocaine; Ethanolamines; Guanethidine; Hallucinogens; Histamine; Imipramine; Isoproterenol; Lysergic Acid Diethylamide; Mast Cells; Metabolism; Methysergide; Mice; Neoplasms; Neoplasms, Experimental; Norepinephrine; Pharmacology; Phenoxybenzamine; Promethazine; Research; Serotonin; Sympatholytics; Tryptamines | 1964 |
EFFECTS OF D-AMPHETAMINE UPON OPERANT BEHAVIOR OF PIGEONS: ENHANCEMENT BY RESERPINE.
Topics: Animals; Behavior, Animal; Birds; Cocaine; Columbidae; Conditioning, Psychological; Dextroamphetamine; Imipramine; Movement; Piperidines; Psychopharmacology; Research; Reserpine | 1964 |
INHIBITION OF NORADRENALINE UPTAKE BY DRUGS.
Topics: Bretylium Compounds; Carbon Isotopes; Chlorpromazine; Cocaine; Desipramine; Guanethidine; Heart; Imipramine; Monoamine Oxidase Inhibitors; Norepinephrine; Pharmacology; Rats; Research; Reserpine; Sympatholytics | 1965 |
POTENTIATION OF NOREPINEPHRINE IN THE ISOLATED VAS DEFERENS OF THE RAT BY SOME CNS STIMULANTS AND ANTIDEPRESSANTS.
Topics: Amitriptyline; Antidepressive Agents; Central Nervous System Stimulants; Chlorpromazine; Chlorprothixene; Cocaine; Desipramine; Humans; Imipramine; Male; Methylphenidate; Norepinephrine; Pharmacology; Phenmetrazine; Piperidines; Rats; Research; Tranquilizing Agents; Vas Deferens | 1965 |
[THE MECHANISM OF ACTION OF RESERPINE REVERSAL WITH DESMETHYLIMIPRAMIN].
Topics: Catecholamines; Cocaine; Imipramine; Rats; Research; Reserpine | 1965 |
SYMPATHEIC STIMULATION AND BLOCKADE OF THE URINARY BLADDER IN CAT.
Topics: Acetylcholine; Atropine; Bretylium Compounds; Cats; Choline; Cocaine; Dopamine; Electric Stimulation; Ergotamine; Guanethidine; Hexamethonium Compounds; Hypogastric Plexus; Imipramine; Methyltyrosines; Norepinephrine; Pharmacology; Phentolamine; Physostigmine; Research; Reserpine; Serotonin; Sympathetic Nervous System; Tyramine; Tyrosine; Urinary Bladder | 1964 |
ANTAGONISM OF THE BLOCKING ACTION OF BRETYLIUM AND GUANETHIDINE ON THE PRESSOR EFFECT OF PHYSOSTIGMINE IN THE RAT.
Topics: Amphetamine; Amphetamines; Blood Pressure; Bretylium Compounds; Cocaine; Dextroamphetamine; Guanethidine; Imipramine; Methylphenidate; Norepinephrine; Pharmacology; Physostigmine; Rats; Research; Reserpine; Sympatholytics; Vasoconstrictor Agents; Vasomotor System | 1965 |
Cocaine and other indirect-acting monoamine agonists differentially attenuate a naltrexone discriminative stimulus in morphine-treated rhesus monkeys.
Topics: Amphetamine; Animals; Biogenic Monoamines; Cocaine; Discrimination Learning; Disease Models, Animal; Dopamine Agents; Dopamine Uptake Inhibitors; Drug Interactions; Imipramine; Macaca mulatta; Morphine; Morphine Dependence; Naltrexone; Narcotics; Substance Withdrawal Syndrome | 2004 |
Monoaminergic drugs and directly observable signs of LAAM withdrawal in rhesus monkeys.
Topics: Adrenergic alpha-Agonists; Amphetamine; Analgesics, Opioid; Animals; Antidepressive Agents, Tricyclic; Biogenic Monoamines; Clonidine; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Haloperidol; Imipramine; Macaca mulatta; Male; Methadyl Acetate; Muscle Rigidity; Naltrexone; Narcotic Antagonists; Respiratory Mechanics; Salivation; Substance Withdrawal Syndrome | 2005 |
G(olf) protein levels in rat striatum are increased by chronic antidepressant administration and decreased by olfactory bulbectomy.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Cocaine; GTP-Binding Protein alpha Subunits; Imipramine; Male; Neostriatum; Olfactory Bulb; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Time Factors; Up-Regulation | 2006 |
Evidence for the presence of histamine uptake into the synaptosomes of rat brain.
Topics: Animals; Biological Transport; Brain; Cocaine; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Imipramine; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Receptors, Histamine; Synaptosomes | 2006 |
Comparative metabolic capabilities and inhibitory profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17.
Topics: Atomoxetine Hydrochloride; Cocaine; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Debrisoquin; Dextromethorphan; Enzyme Inhibitors; Ethanolamines; Fluoxetine; Humans; Hydroxylation; Imipramine; Kinetics; Microsomes; Molecular Structure; Nortriptyline; Polymorphism, Single Nucleotide; Propylamines; Quinidine; Recombinant Proteins; Thioridazine; Tramadol | 2007 |
Effect of cannabinoids on platelet serotonin uptake.
Topics: Adult; Arachidonic Acids; Benzoxazines; Blood Platelets; Cannabinoids; Cell Membrane; Cocaine; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Female; Humans; Imipramine; In Vitro Techniques; Male; Marijuana Smoking; Morpholines; Naphthalenes; Polyunsaturated Alkamides; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sex Characteristics; Viscosity | 2007 |
Fluoxetine (Prozac) binding to serotonin transporter is modulated by chloride and conformational changes.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Binding Sites; Chlorides; Cocaine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Fluoxetine; Ibogaine; Imipramine; Models, Chemical; Mutation; Protein Conformation; Protein Stability; Rats; RNA-Binding Proteins | 2009 |
Effects of imipramine or GABA(B) receptor ligands on the immobility, swimming and climbing in the forced swim test in rats following discontinuation of cocaine self-administration.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cocaine; Depressive Disorder; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Imipramine; Injections; Ligands; Locomotion; Male; Motivation; Rats; Rats, Wistar; Receptors, GABA-B; Self Administration; Sodium Chloride; Stress, Physiological; Swimming; Time Factors | 2010 |
Cocaine sensitization models an anhedonia-like condition in rats.
Topics: Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Cocaine; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Uptake Inhibitors; Imipramine; Male; Maze Learning; Motor Activity; Nucleus Accumbens; Phosphorylation; Pleasure; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Taste | 2011 |
Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers.
Topics: Affect; Amitriptyline; Animals; Antidepressive Agents; Antimanic Agents; Benzodiazepines; Cerebral Cortex; Citalopram; Clorgyline; Cocaine; Cyclohexanols; Desipramine; Fluoxetine; Imipramine; In Vitro Techniques; Iproniazid; Lithium; Mianserin; Mirtazapine; Mitochondria; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Morpholines; Olanzapine; Pargyline; Reboxetine; Swine; Thiazepines; Valproic Acid; Venlafaxine Hydrochloride | 2010 |
Interactions between dopamine transporter and cannabinoid receptor ligands in rhesus monkeys.
Topics: Amphetamine; Animals; Cocaine; Discrimination Learning; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Dronabinol; Female; Haloperidol; Imipramine; Macaca mulatta; Male; Piperidines; Pyrazoles; Receptors, Cannabinoid; Rimonabant; Tropanes | 2012 |
In silico study on the inhibitory interaction of drugs with wild-type CYP2D6.1 and the natural variant CYP2D6.17.
Topics: Cocaine; Computer Simulation; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Enzyme Inhibitors; Fluoxetine; Imipramine; Molecular Docking Simulation; Molecular Dynamics Simulation; Organic Chemicals; Polymorphism, Genetic; Protein Conformation; Quinidine; Regression Analysis; Stereoisomerism; Thioridazine | 2014 |
Effects of escitalopram and imipramine on cocaine reinforcement and drug-seeking behaviors in a rat model of depression.
Topics: Animals; Citalopram; Cocaine; Cocaine-Related Disorders; Cues; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Imipramine; Male; Motor Activity; Olfactory Bulb; Psychotropic Drugs; Rats, Wistar; Reinforcement, Psychology; Self Administration | 2017 |