imipramine has been researched along with clomipramine in 298 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 173 (58.05) | 18.7374 |
| 1990's | 68 (22.82) | 18.2507 |
| 2000's | 31 (10.40) | 29.6817 |
| 2010's | 23 (7.72) | 24.3611 |
| 2020's | 3 (1.01) | 2.80 |
| Authors | Studies |
|---|---|
| Cook, RB; Davis, DP; Eichstadt, KE; Reepmeyer, JC; Riley, PG; Wiley, RA | 1 |
| Biziere, K; Bouchet, MJ; Bourguignon, JJ; Kan, JP; Maghioros, G; Moire, C; Schlewer, G; Wermuth, CG; Worms, P | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Costanzo, MJ; Gardocki, JF; Maryanoff, BE; McComsey, DF; Nortey, SO; Schneider, CR; Setler, PE; Shank, RP | 1 |
| Bonnaud, B; Briley, M; Cousse, H; Couzinier, JP; Fauran, F; Mouzin, G; Stenger, A | 1 |
| Chiang, GH; Unger, SH | 1 |
| Högberg, T; Renyi, AL; Ross, SB; Ulff, B | 1 |
| Pajeva, I; Wiese, M | 1 |
| Medina-Hernández, MJ; Quiñones-Torrelo, C; Sagrado, S; Villanueva-Camañas, RM | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Ikeda, K; Kobayashi, T; Washiyama, K | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Gouaux, E; Singh, SK; Yamashita, A | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Choi, K; Moon, B; Park, JE; Roh, EJ; Sim, T; Song, C | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Artursson, P; Mateus, A; Matsson, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Fry, EE; Ren, J; Stuart, DI; Townsend, AR; Xiao, J; Zhao, Y | 1 |
| Alonso, C; Campillo, NE; Cuesta-Geijo, MÁ; Delgado, R; Gil, C; Ginex, T; Morales-Tenorio, M; Muñoz-Fontela, C | 1 |
| Cardoso, FC; Duggan, PJ; Kuiper, MJ; Lewis, RJ; Schmit, M; Tuck, KL | 1 |
| Chen, W; Han, S; Hu, Y; Li, H; Tong, X; Yang, L; Zuo, J | 1 |
| Nagy, A | 2 |
| Cohen, D; Weinstock, M | 1 |
| Kocher, R | 4 |
| Dresse, A; Dubois, M; Scuvée-Moreau, J | 1 |
| Fromm, GH; Glass, JD | 1 |
| Delini-Stula, A; Radeke, E; Vassout, A | 1 |
| Lüllmann-Rauch, R; Scheid, D | 1 |
| Lüllmann-Rauch, R | 2 |
| Carlsson, I; Lagerström, PO; Persson, BA | 1 |
| Franz, DN; Sangdee, C | 1 |
| Ueki, S; Yamamoto, T | 1 |
| Fletcher, HP; Schnell, RC; Wannarka, GL | 1 |
| Anlezark, G; Meldrum, B; Trimble, M | 1 |
| Johansson, R; Nagy, A | 1 |
| Korf, J; Meisch, JJ; van Wijk, M | 1 |
| Broitman, ST; Donoso, AO | 1 |
| Lassen, JB | 1 |
| Dujovne, CA; Ueda, I; Yasuhara, H | 1 |
| Briley, M; Langer, SZ; Raisman, R | 1 |
| Hole, G; Pühringer, W; Wirz-Justice, A | 1 |
| Dürst, T; Glatt, A; Klebs, K; Koella, WP | 1 |
| Alkalay, D; Carlsen, S; Volk, J | 1 |
| Bunney, WE; Gallager, DW | 1 |
| Calil, HM; Goodwin, FK; Manian, AA; Potter, WZ; Zavadil, AP | 1 |
| Johnsson, G; Lundborg, P; Welin-Fogelberg, I | 1 |
| Borg, KO; Johnsson, G; Jordö, L; Lundborg, P; Rönn, O; Welin-Fogelberg, I | 1 |
| Delini-Stula, A; Vassout, A | 2 |
| Huey, LY; Janowsky, DS; Risch, SC | 1 |
| Howarth, AT | 1 |
| Horn, AS | 1 |
| Montplaisir, J | 1 |
| Dresse, A; Fischer, P; Scuvee-Moreau, J | 1 |
| Escande, M; Gayral, L; Golberger, E; Jarrige, A; Kulik, J | 1 |
| Meltzer, HY; Stahl, SM | 1 |
| Aghamanian, GK; Davis, M; Gallager, DW | 1 |
| Buckley, JP; Jandhyala, BS; Manian, AA; Perel, JM; Steenberg, ML | 1 |
| de Gaetano, G; Garattini, S; Miragliotta, G; Roncaglioni, MC; Wielosz, M | 1 |
| Moore, KE; Wuerthele, SM | 1 |
| Anlezark, G; Meldrum, BS; Trimble, MR | 1 |
| Campbell, IC | 1 |
| Brase, DA; Loh, HH | 1 |
| Bake, B; Dencker, SJ | 1 |
| Baba, O; Fujiwara, J; Hanaoka, M; Ishino, H; Sasaki, K | 1 |
| Francesconi, R; Mager, M | 1 |
| Andrée, G; Meiser, H; Schmitt, W | 1 |
| Detaevernier, MR; Dryon, L; Massart, DL | 1 |
| de Gaetano, G; Garattini, S; Salmona, M; Wielosz, M | 1 |
| Klimek, V; Maj, J; Rawlów, A; Sarnek, J | 1 |
| Babcock, DA; Dement, WC; Mitler, MM; Narver, EL | 1 |
| Ban, TA; Gratton, L; Klingner, A; Pecknold, JC | 1 |
| Ashcroft, GW | 1 |
| Bossa, R; Dubini, F; Galatulas, I; Tofanetti, O | 1 |
| Krupp, P; Wesp, M | 1 |
| Oksenkrug, GF | 1 |
| Dubois, JP; Küng, W; Theobald, W; Wirz, B | 1 |
| Kunihara, M; Nakano, M; Ohyama, M | 1 |
| De Felipe, MC; Del Rio, J; Montero, D; Romero, G; Toscano, E | 1 |
| Alling, DW; Levenbook, L; Weinbach, EC | 1 |
| Guelfi, JD; Roth, M | 1 |
| Bertschy, G; Bizouard, P; Bonin, B; François, TH; Nezelof, S; Sechter, D; Vandel, B; Vandel, S | 1 |
| Eriksson, E; Modigh, K; Westberg, P | 1 |
| Molina, VA; Murua, VS | 1 |
| Balant, LP; Balant-Gorgia, AE; Gay, M; Gex-Fabry, M | 1 |
| Davis, JM; Dysken, MW; Kim, SW; Pandey, GN | 1 |
| Clissold, SP; Dechant, KL | 1 |
| Aizenberg, D; Hermesh, H; Karp, L; Weizman, A; Zemishlany, Z | 1 |
| Eriksson, E; Lisjö, P; Modigh, K; Westberg, P | 1 |
| Hegenscheid, B; Presber, HW | 1 |
| Black, DW; Kelly, M; Myers, C; Noyes, R | 1 |
| Mellerup, ET; Plenge, P | 2 |
| Lange, KW | 1 |
| Tiller, JW | 1 |
| Chatelain, F; Martin, P; Massol, J; Puech, AJ | 1 |
| Egeler-Peerdeman, SM; Taphoorn, MJ; Visscher, F | 1 |
| Jones, GR; Pounder, DJ | 1 |
| Møller, SE | 1 |
| Lavoie, PA; Tiberi, M | 1 |
| Belon, JP; Martin, P; Massol, J; Puech, AJ; Soubrié, P | 1 |
| Billa, JP; Dufour, P; Fabre, J; Roquebert, J | 1 |
| Fukuzako, H; Hirakawa, K; Hokazono, Y; Matsumoto, K; Tominaga, H | 1 |
| Garreau, M; Magni, G; Orofiamma, B; Palminteri, R | 1 |
| Sauter, C | 1 |
| Balant, LP; Balant-Gorgia, AE; Garrone, G | 1 |
| Danti, S; Fermanian, J; Frances, H | 1 |
| De Potter, WP; Schoups, AA | 1 |
| Ohi, K; Shimoda, K; Takahashi, K; Takahashi, S; Tsujimoto, T; Yamada, N | 1 |
| Chatelain, F; Martin, P; Massol, J; Puech, AJ; Soubrié, P | 1 |
| Ferrari, C; Marmiroli, N; Puglisi, PP; Sabatini, MA; Tedeschi, F; Truzzi, G | 1 |
| Hölzl, G; Krüger, R; Kuss, HJ; Schefold, L | 2 |
| Araki, Y; Eto, K; Fukuda, T; Inoue, B; Ogata, M | 1 |
| Bradley, D; Claggett, CE; Costa, JL; Hundal, T; Morris, SJ; Nelson, BD; Weinbach, EC | 1 |
| Briley, M; Moret, C | 1 |
| Mellerup, ET; Plenge, P; Rafaelsen, OJ | 1 |
| Garcia, MC; Kenney, RM; McDonnell, SM | 1 |
| Ishikura, Y; Ono, H; Yokota, S | 1 |
| Martin, KF; Redfern, PH | 1 |
| Eriksson, K; Marcusson, J | 1 |
| Aulakh, CS; Hill, JL; Murphy, DL; Wozniak, KM | 1 |
| Bourhim, N; Cantau, P; Carydakis, C; Castanas, E; Giraud, P; Oliver, C | 1 |
| Benkelfat, C; Galzin, AM; Langer, SZ; Loo, H; Pimoule, C; Poirier, MF; Schoemaker, H; Sechter, D; Segonzac, A; Zarifian, E | 1 |
| Bartholini, G; Depoortere, H; Lloyd, KG; Sanger, D; Zivkovic, B | 1 |
| Martin, P; Massol, J; Puech, AJ; Soubrié, P | 1 |
| Domínguez-Gil, A; Fernández de Gatta, MM; García, MJ; Gutierrez, JR; Tamayo, M | 1 |
| Hrdina, PD | 1 |
| Modigh, K | 1 |
| Baumann, P; Cuendet, C; Eap, CB | 1 |
| Belon, JP; Gaudel, G; Martin, P; Massol, J; Soubrié, P | 1 |
| Christensen, P | 1 |
| Kane, JM; Lieberman, JA; Reife, R | 1 |
| Ananth, J | 1 |
| Lei, BS | 1 |
| Dugger, D; Foa, EB; Kozak, MJ; Steketee, G | 1 |
| Riley, AJ; Riley, EJ | 1 |
| Severson, JA; Wilcox, RE; Woodward, JJ | 1 |
| el Mestikawy, S; Hamon, M; Martin, P; Simon, P; Soubrie, P; Thiebot, MH | 1 |
| Fischer, W; Heydenreich, F; Rabending, G; Streubel, FR | 1 |
| Furuta, J; Hamahara, A; Kin, H; Sano, J; Sumiya, N | 1 |
| Chuang, DM; Costa, E; Nakaki, T; Roth, BL | 1 |
| Jacob, R; Mavissakalian, M; Michelson, L; Turner, SM | 1 |
| Neziroglu, F; Volavka, J; Yaryura-Tobias, JA | 1 |
| Lingjaerde, O | 1 |
| Lamb, RJ; McMillan, DE | 1 |
| Costa, JL; Weinbach, EC; Wieder, SC | 1 |
| Anderson, RJ; Fletcher, EC; Rumack, BH; Vestal, BK; Wolfe, R | 1 |
| Balashova, MG; Lobova, EK; Smulevich, AB; Vorob'ev, VIu; Zavidovskaia, GI | 1 |
| Asberg, M | 1 |
| Kocher, R; Rohrer, G | 1 |
| Couper-Smartt, JD; Rodham, R | 1 |
| Dresse, A; Van Dorsser, W | 1 |
| Benkelfat, C; Galzin, AM; Langer, SZ; Loo, H; Poirier, MF; Schoemaker, H; Sechter, D; Segonzac, A; Zarifian, E | 1 |
| Brown, WA; Haier, RJ; Qualls, CB | 2 |
| Taylor, CB; Tearnan, BH; Telch, MJ | 1 |
| Cobb, J | 1 |
| Bianchetti, G; Dugas, M; Morselli, PL | 1 |
| Burkard, WP; Da Prada, M; Keller, HH | 1 |
| Bonetti, EP; Burkard, WP; Da Prada, M; Haefely, W; Keller, HH; Launay, JM; Schaffner, R | 1 |
| Hall, H; Lindbom, LO; Malatray, J; Ogren, SO | 1 |
| Acosta, E; Arocha, L; Gómez, F; Lechin, E; Lechin, F; Van der Dijs, B | 1 |
| Rozhanets, VV; Rusakov, DIu; Tarasova, EV; Val'dman, AV | 1 |
| Fennessy, MR; Taylor, DA; Verberne, AJ | 1 |
| Svensson, TH | 1 |
| Scuvée-Moreau, JJ; Svensson, TH | 1 |
| Mavissakalian, M; Michelson, L | 1 |
| Mehendale, HM; Morita, T | 1 |
| Larsen, OB; Møller, SE | 1 |
| Gram, LF; Kragh-Sørensen, P; Kristensen, CB; Møller, M; Pedersen, OL; Thayssen, P | 1 |
| Allerup, P; Bech, P; Gram, LF; Reisby, N | 1 |
| Elley, J; Krautwald, O; Møller, SE; Ortmann, J; Reisby, N | 1 |
| Dwyer, DM; Zilberstein, D | 1 |
| Gillin, JC; Insel, TR; Mueller, EA; Murphy, DL; Siever, LJ | 1 |
| Hess, CW | 1 |
| Battistini, N; Borghesi, R; Della Corte, L; Nardini, M; Ninci, R; Sgaragli, GP | 1 |
| Della Corte, L; Franco, C; Giovannini, MG; Nardini, M; Ninci, R; Sgaragli, GP | 1 |
| Kobayashi, A; Nakazawa, K; Sugita, S | 1 |
| Itoh, M; Nakao, H; Notomi, A; Yufu, N | 1 |
| Bonnet, JJ; Costentin, J; Lemasson, MH | 1 |
| Harrison-Read, PE; Steinberg, H | 1 |
| Constantinidis, J; Dick, P; Tissot, R | 1 |
| Vinet, B | 1 |
| Briley, MS; Langer, SZ; Sette, M | 1 |
| Paul, SM; Rehavi, M; Skolnick, P | 1 |
| Bräunlich, H; Fleck, C | 1 |
| Brown, WA; Qualls, CB | 1 |
| Meierl, G; Schmidt, WJ | 1 |
| Braithwaite, RA | 1 |
| Ziebarth, D | 1 |
| Berchou, R; Pohl, R; Rainey, JM | 1 |
| Cicardo, VH; Osman Dick, G | 1 |
| Avdulov, NA; Maĭsov, NI | 1 |
| Gauron, S; Godbillon, J | 1 |
| Górka, Z; Kwiatek, H; Pawłowski, L | 1 |
| Avdulov, NA; Dobretsov, GE; Val'dman, AV | 1 |
| Bazán, E; Fuentes, JA; Galindo, A; Guillamón, A; Somoza, E; Valencia, A | 1 |
| McGuire, PS; Seiden, LS | 1 |
| Argiolas, A; Fadda, F; Gessa, GL; Serra, G | 1 |
| Bech, P; Gram, LF; Rafaelsen, OJ; Reisby, N | 1 |
| Bergmann, R; Brust, P; Johannsen, B | 1 |
| Bastide, P; Coudert, P; Rubat, C; Tronche, P | 1 |
| Parkes, D | 1 |
| Eidelman, AI; Schimmel, MS | 1 |
| Aulakh, CS; Hulihan-Giblin, BA; Park, YD | 1 |
| Asakura, W; Matsumoto, K; Ohta, H; Watanabe, H | 1 |
| Arimoto, H; Fujii, T; Kurihara, Y; Mitsutsuka, Y | 1 |
| Helbing-Zwanenburg, B; Kamphuisen, HA; Mourtazaev, MS | 1 |
| Coutts, RT | 1 |
| Kato, T; Murashita, J; Shioiri, T; Takahashi, S; Yamada, N | 1 |
| Balon, R; Pohl, R; Ramesh, C; Yeragani, VK | 1 |
| Aulakh, CS; Hill, JL; Murphy, DL | 1 |
| Bellmann, R; Sperk, G | 1 |
| Ichikawa, J; Meltzer, HY | 1 |
| Gambarana, C; Ghiglieri, O; Graziella de Montis, M | 1 |
| Miranda, HF; Pinardi, G; Sierralta, F | 1 |
| Gentil, V; Gorenstein, C; Ito, LM; Miyakawa, E | 1 |
| Mendez, M; Miranda, HF; Pinardi, G; Sierralta, F | 1 |
| Erjavec, F; Ferjan, I | 1 |
| Buxeraud, J; Comby, F; Raby, C; Rousseau, A | 1 |
| Bech, P; Damsbo, N; Fuglum, E; Lauritzen, L; Rosenberg, C; Stage, K | 1 |
| Artigas, F; Bel, N; Casanovas, JM; Romero, L | 1 |
| Ichikawa, H; Mitsushio, H; Shirayama, Y; Takahashi, K; Takashima, M | 1 |
| DePierre, JW; Nässberger, L; Xia, Z | 1 |
| Kumazawa, T; Lee, XP; Sato, K; Suzuki, O | 1 |
| Appelkvist, EL; DePierre, JW; Nässberger, L; Xia, Z | 1 |
| Balant, L; Busquets, X; Escribá, PV; García-Sevilla, JA; Guimón, J; Walzer, C | 1 |
| Aymard, G; Diquet, B; Livi, P; Pham, YT | 1 |
| Shimizu, T | 1 |
| Bayley, PJ; Bentley, GD; Dawson, GR | 1 |
| Betz, H; Schloss, P; Sur, C | 1 |
| Bovier, P; Karege, F; Malafosse, A; Stepanian, R | 1 |
| Ballesta, J; de la Torre, R; González, S; Ortuño, J; Pascual, JA | 1 |
| Fukuda, H; Obata, T; Okubo, Y; Sasaki, Y; Sudo, Y; Suhara, T; Suzuki, K; Yoshida, K; Yoshikawa, K | 1 |
| Chang, HC; Cheng, JT; Hsieh, CH; Hsieh, JT; Law, HS | 1 |
| Chen, JX; Gershon, MD; Pan, H; Rothman, TP; Wade, PR | 1 |
| Bengtsson, BO; Ekerling, L; Link, H; Mix, E; Olsson, T; Thorell, LH; Zhu, J | 1 |
| Asbun, J; Castillo, C; Castillo, EF; Ocharan, ME; Valencia, I | 1 |
| Armario, A; Gómez, F; Graugés, P; Martín, M | 1 |
| Graham, BG; Sattely-Miller, EA; Schiffman, SS; Suggs, MS | 1 |
| Cerniglia, CE; Dovichi, NJ; Hansen, EB; Li, XF; Liu, CS; Roos, P | 1 |
| Cerniglia, CE; Dovichi, NJ; Hansen, EB; Li, XF; Liu, CS; Pinto, D | 1 |
| Meyers, BS | 1 |
| Bergstrand, A; DePierre, JW; Nässberger, L; Xia, Z | 1 |
| Gómez Gómez, JM; Teixidó Perramón, C | 1 |
| Akiskal, HS; Frare, F; Mata, B; Mengali, F; Perugi, G; Recchia, M; Serra, G; Toni, C; Vitale, B | 1 |
| Judge, R; Montgomery, SA | 1 |
| Manev, H; Manev, R; Smalheiser, NR; Uz, T | 1 |
| Bergstrand, A; DePierre, JW; Lundgren, B; Nässberger, L; Xia, Z | 1 |
| Okuyama, S; Takamori, K; Yoshida, S | 1 |
| Fernandez-Belda, F; Fortea, I; Plenge-Tellechea, F; Soler, F | 1 |
| Barańczyk-Kuźma, A; Jagiełło, J; Kuźma, M; Sawicki, J | 1 |
| Hashimoto, K; Ichimiya, T; Inoue, M; Sudo, Y; Suhara, T; Suzuki, K; Takano, A; Yasuno, F; Zhang, MR | 1 |
| DePierre, JW; Karlsson, H; Nässberger, L; Ying, G | 1 |
| Abdel-Salam, OM; El-Shenawy, SM; Nofal, SM | 1 |
| Nagaraja, MR; Sharada, S; Subhash, MN; Vinod, KY | 1 |
| Miyaoka, H; Shibuya, A; Suzuki, E; Yoshida, Y | 1 |
| Barańczyk-Kuźma, A; Gutowicz, M; Kaźmierczak, B; Kuźma, M; Sawicki, J | 1 |
| Alenezi, AM; BaHammam, AS | 1 |
| Nika, MK; Papadoyannis, IN; Samanidou, VF | 1 |
| Alves, C; Fernandes, C; Lanças, FM; Rodrigues, JC; Santos-Neto, AJ | 1 |
| Arce, R; García, C; Hernández, D; Oyola, R; Piñero, L | 1 |
| Hwang, J; Kim, SH; Lee, HW; Lee, MG; Lee, WH; Ock, J; Park, HC; Suk, K; Zheng, LT | 1 |
| Birowo, P; Jonas, U; Kedia, GT; Kuczyk, MA; Meyer, M; Rahardjo, D; Scheller, F; Taher, A; Uckert, S | 1 |
| Asselman, P; Baraitser, M; Marsden, CD; Parkes, JD | 1 |
| Booth-Genthe, CL; Grimm, SW; Guo, J; Linnenbach, AJ; Zhou, D | 1 |
| Naqvi, AZ; Rub, MA | 1 |
| Araujo Escalona, AG; Estrada-Reyes, R; Heinze, G; Ledesma Velázquez, I; Martínez-Mota, L; Martínez-Vázquez, M; Moreno, J | 1 |
| Antila, H; Castrén, E; Di Lieto, A; Lindholm, J; Rantamäki, T; Rios, M; Tessarollo, L; Vesa, L; Yanpallewar, S | 1 |
| Davarani, SS; Najarian, AM; Nojavan, S; Tabatabaei, MA | 1 |
| Ferjan, I; Lipnik-Štangelj, M | 1 |
| Ishikawa, M; Maekawa, K; Murayama, M; Nakatsu, N; Saito, K; Saito, Y; Senoo, Y; Urata, M; Yamada, H | 1 |
| Berm, EJJ; Brummel-Mulder, E; Hak, E; Maring, JG; Paardekooper, J; Wilffert, B | 1 |
| Cipriani, A; Coghill, D; Cohen, D; Cuijpers, P; Del Giovane, C; Hazell, P; Hetrick, SE; Leucht, S; Liu, L; Liu, Y; Michael, KD; Pu, J; Qin, B; Ravindran, AV; Whittington, C; Xie, P; Yang, L; Zhang, Y; Zhou, X | 1 |
| Nasiri-Aghdam, M; Nojavan, S; Rahmani, T; Shaghaghi, H; Shokri, A | 1 |
| Citterio, D; Hiruta, Y; Imai, H; Kumagai, H; Mochida, M; Nagai, Y | 1 |
22 review(s) available for imipramine and clomipramine
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Potential pharmacological strategies targeting the Niemann-Pick C1 receptor and Ebola virus glycoprotein interaction.
Topics: Antibodies; Ebolavirus; Glycoproteins; Hemorrhagic Fever, Ebola; Humans; Molecular Docking Simulation; Niemann-Pick C1 Protein; Protein Binding; Small Molecule Libraries; Virus Internalization | 2021 |
Paroxetine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in depressive illness.
Topics: Amitriptyline; Animals; Antidepressive Agents; Clomipramine; Depressive Disorder; Drug Evaluation; Drug Tolerance; Humans; Imipramine; Paroxetine; Piperidines; Serotonin Antagonists | 1991 |
[Narcolepsy].
Topics: Adolescent; Adult; Amphetamine; Cataplexy; Child; Clomipramine; Diagnosis, Differential; Female; Humans; Imipramine; Male; Mazindol; Methylphenidate; Narcolepsy; Phenmetrazine | 1990 |
Tryptophan to competing amino acids ratio in depressive disorder: relation to efficacy of antidepressive treatments.
Topics: Amino Acids; Amitriptyline; Antidepressive Agents; Brain; Brain Chemistry; Clomipramine; Depressive Disorder; Drug Therapy, Combination; Humans; Hydroxyindoleacetic Acid; Imipramine; Lithium; Metabolic Clearance Rate; Norepinephrine; Serotonin; Tryptophan; Tyrosine | 1985 |
Antidepressant drugs in anxiety disorders.
Topics: Antidepressive Agents; Anxiety Disorders; Clomipramine; Humans; Imipramine; Monoamine Oxidase Inhibitors; Obsessive-Compulsive Disorder; Panic | 1987 |
Neuromuscular effects of monoamine oxidase inhibitors.
Topics: 5-Hydroxytryptophan; Adult; Animals; Clomipramine; Clorgyline; Depressive Disorder; Female; Humans; Imipramine; Male; Middle Aged; Models, Biological; Monoamine Oxidase Inhibitors; Myoclonus; Neuromuscular Junction; Pargyline; Serotonin; Sleep, REM; Spasms, Infantile; Tranylcypromine; Trifluoperazine | 1986 |
Clomipramine: an antiobsessive drug.
Topics: Anxiety; Behavior Therapy; Clinical Trials as Topic; Clomipramine; Compulsive Behavior; Depressive Disorder; Diazepam; Haloperidol; Humans; Imipramine; Nortriptyline; Obsessive Behavior; Obsessive-Compulsive Disorder; Phobic Disorders; Psychological Tests | 1986 |
From clomipramine to mianserin: therapeutic relevance of interactions with serotonin uptake and storage, as studied in the blood platelet model.
Topics: Antidepressive Agents; Biological Transport; Blood Platelets; Blood Proteins; Citalopram; Clomipramine; Cytoplasmic Granules; Depression, Chemical; Humans; Imipramine; Kinetics; Propylamines; Protein Binding; Reserpine; Serotonin | 1985 |
Individualization of treatment with tricyclic compounds.
Topics: Animals; Antidepressive Agents; Chromatography, Gas; Clomipramine; Depression; Drug Interactions; Electrocardiography; Humans; Imipramine; Kinetics; Norepinephrine; Nortriptyline; Rats; Serotonin; Time Factors | 1974 |
Antidepressant medication in the treatment of agoraphobia: a critical review.
Topics: Agoraphobia; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior Therapy; Clomipramine; Combined Modality Therapy; Desensitization, Psychologic; Double-Blind Method; Humans; Imipramine; Monoamine Oxidase Inhibitors; Patient Compliance; Phenelzine; Phobic Disorders; Psychotherapy; Research Design; Substance Withdrawal Syndrome; Time Factors | 1983 |
Behaviour therapy in phobic and obsessional disorders.
Topics: Agoraphobia; Arousal; Behavior Therapy; Clomipramine; Cognition; Combined Modality Therapy; Desensitization, Psychologic; Humans; Imipramine; Marriage; Obsessive-Compulsive Disorder; Phobic Disorders; Professional-Patient Relations; Prognosis; Time Factors | 1983 |
Effect of chronic treatment with tricyclic antidepressant drugs on identified brain noradrenergic and serotonergic neurons.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Clonidine; Drug Interactions; Imipramine; Iontophoresis; Lysergic Acid Diethylamide; Male; Neurons; Norepinephrine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Serotonin; Yohimbine | 1980 |
Tryptophan and tyrosine availability: relation to clinical response to antidepressive pharmacotherapy.
Topics: Amitriptyline; Antidepressive Agents; Clomipramine; Depressive Disorder; Humans; Imipramine; Lithium; Prognosis; Tryptophan; Tyrosine | 1984 |
Plasma level monitoring of antidepressants: theoretical basis and clinical application.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Genetic Variation; Humans; Imipramine; Kinetics; Nortriptyline; Oxidation-Reduction; Patient Compliance; Pharmacogenetics | 1984 |
Plasma-protein binding of tricyclic antidepressants.
Topics: Aged; Antidepressive Agents, Tricyclic; Binding Sites; Blood Proteins; Clomipramine; Humans; Imipramine; Maprotiline; Protein Binding | 1980 |
Introduction to the mechanism of action of different treatments of narcolepsy.
Topics: Amphetamine; Brain; Clomipramine; Drug Therapy, Combination; Humans; Imipramine; Narcolepsy | 1994 |
Polymorphism in the metabolism of drugs, including antidepressant drugs: comments on phenotyping.
Topics: Clomipramine; Cytochromes; Dealkylation; Depressive Disorder; Desipramine; Dextromethorphan; Drug Interactions; Female; Humans; Hydroxylation; Imipramine; Isoenzymes; Male; Mephenytoin; Nortriptyline; Phenotype; Polymorphism, Genetic | 1994 |
[Narcolepsy].
Topics: Antidepressive Agents, Tricyclic; Central Nervous System Stimulants; Clomipramine; Diagnosis, Differential; HLA Antigens; Humans; Imipramine; Methylphenidate; Narcolepsy; Reference Standards | 1998 |
Depression and dementia: comorbidities, identification, and treatment.
Topics: Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Benzamides; Citalopram; Clomipramine; Cognition Disorders; Comorbidity; Dementia; Depression; Female; Fluoxetine; Fluvoxamine; Humans; Imipramine; Male; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Neuropsychological Tests; Nortriptyline; Selective Serotonin Reuptake Inhibitors; Sertraline | 1998 |
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.
Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Confounding Factors, Epidemiologic; Depressive Disorder, Major; Desipramine; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Evidence-Based Medicine; Fluoxetine; Humans; Imipramine; Mianserin; Mirtazapine; Nortriptyline; Paroxetine; Piperazines; Randomized Controlled Trials as Topic; Research Design; Sertraline; Treatment Outcome; Triazoles; Venlafaxine Hydrochloride | 2016 |
24 trial(s) available for imipramine and clomipramine
| Article | Year |
|---|---|
Proceedings: Systematic clinical studies with clomipramine in depressed psychiatric patients--III. Standard-controlled clinical trial.
Topics: Adult; Clinical Trials as Topic; Clomipramine; Depression; Dibenzazepines; Female; Humans; Imipramine; Male; Middle Aged; Psychiatric Status Rating Scales | 1976 |
The efficacy of reversible monoamine oxidase inhibitors in depressive illness.
Topics: Antidepressive Agents, Tricyclic; Benzamides; Clomipramine; Depressive Disorder; Humans; Imipramine; Moclobemide; Monoamine Oxidase Inhibitors | 1992 |
Superiority of clomipramine over imipramine in the treatment of panic disorder: a placebo-controlled trial.
Topics: Adult; Clomipramine; Diazepam; Double-Blind Method; Female; Humans; Imipramine; Male; Panic Disorder; Psychiatric Status Rating Scales | 1992 |
Platelet 3H-imipramine binding sites in obsessive-compulsive behavior.
Topics: Adult; Blood Platelets; Carrier Proteins; Clomipramine; Female; Humans; Imipramine; Male; Middle Aged; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Radioligand Assay; Receptors, Drug; Receptors, Neurotransmitter | 1991 |
Tritiated imipramine binding in obsessive-compulsive volunteers and psychiatrically normal controls.
Topics: Adult; Blood Platelets; Carrier Proteins; Clinical Trials as Topic; Clomipramine; Double-Blind Method; Female; Humans; Imipramine; Male; Multicenter Studies as Topic; Obsessive-Compulsive Disorder; Personality Tests; Receptors, Drug; Receptors, Neurotransmitter; Serotonin | 1990 |
Antidepressants, alcohol and psychomotor performance.
Topics: Antidepressive Agents; Anxiety Disorders; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Imipramine; Monoamine Oxidase Inhibitors; Prospective Studies; Psychiatric Status Rating Scales | 1990 |
Fengabine, a new GABAmimetic agent in the treatment of depressive disorders: an overview of six double-blind studies versus tricyclics.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Bipolar Disorder; Chlorophenols; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Psychiatric Status Rating Scales; Random Allocation | 1989 |
Clomipramine: an antiobsessive drug.
Topics: Anxiety; Behavior Therapy; Clinical Trials as Topic; Clomipramine; Compulsive Behavior; Depressive Disorder; Diazepam; Haloperidol; Humans; Imipramine; Nortriptyline; Obsessive Behavior; Obsessive-Compulsive Disorder; Phobic Disorders; Psychological Tests | 1986 |
[A cross-over treatment of obsessive-compulsive neurosis with imipramine and chlorimipramine].
Topics: Adolescent; Adult; Clinical Trials as Topic; Clomipramine; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Obsessive-Compulsive Disorder | 1986 |
Effects of imipramine on depression and obsessive-compulsive symptoms.
Topics: Adolescent; Adult; Aged; Clomipramine; Depressive Disorder; Humans; Imipramine; Middle Aged; Obsessive-Compulsive Disorder; Placebos | 1987 |
[Quantitative EEG analysis of a single dose of psychotropic drugs in healthy probands].
Topics: Adult; Arousal; Brain; Carbamazepine; Clomipramine; Desipramine; Diazepam; Electroencephalography; Evoked Potentials; Female; Haloperidol; Humans; Imipramine; Male; Psychotropic Drugs | 1986 |
Tricyclic antidepressants in obsessive-compulsive disorder: antiobsessional or antidepressant agents? II.
Topics: Adult; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Obsessive-Compulsive Disorder; Placebos; Psychiatric Status Rating Scales; Random Allocation | 1985 |
Clomipramine and imipramine in obsessive-compulsive disorder.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Clomipramine; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Obsessive-Compulsive Disorder | 1985 |
[Treatment of severe chronic pains with a combination of thymoleptics and neuroleptics (author's transl)].
Topics: Adult; Antidepressive Agents; Atropine; Chlorpromazine; Clinical Trials as Topic; Clomipramine; Drug Combinations; Female; Haloperidol; Humans; Imipramine; Male; Methotrimeprazine; Middle Aged; Morphine; Neoplasms; Pain; Papaverine; Tranquilizing Agents | 1974 |
Tricyclic antidepressants in obsessive-compulsive disorder. Antiobsessional or antidepressant agents?
Topics: Adolescent; Adult; Aged; Anxiety; Clinical Trials as Topic; Clomipramine; Depression; Female; Humans; Imipramine; Male; Middle Aged; Obsessive-Compulsive Disorder; Personality Inventory; Psychiatric Status Rating Scales | 1983 |
Assessment of symptom change from improvement curves on the Hamilton depression scale in trials with antidepressants.
Topics: Adult; Aged; Antidepressive Agents; Clomipramine; Depressive Disorder; Female; Humans; Imipramine; Male; Middle Aged; Psychiatric Status Rating Scales; Time Factors | 1984 |
Changes in the frequency distribution pattern of body weight in patients with major depression.
Topics: Adult; Antidepressive Agents, Tricyclic; Body Weight; Clomipramine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Hospitalization; Humans; Imipramine; Male; Middle Aged; Personality Inventory; Sex Factors; Weight Gain; Weight Loss | 1993 |
Minnesota Multiphasic Personality Inventory correlates of panic disorder with agoraphobia: changes with treatment.
Topics: Adolescent; Adult; Agoraphobia; Antidepressive Agents, Tricyclic; Clomipramine; Female; Humans; Imipramine; Male; Middle Aged; MMPI; Panic Disorder | 1995 |
Screening and treating depressed patients. A comparison of two controlled citalopram trials across treatment settings: hospitalized patients vs. patients treated by their family doctors. Danish University Antidepressant Group.
Topics: Citalopram; Clomipramine; Depressive Disorder; Family Practice; Female; Humans; Imipramine; Male; Observer Variation; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors | 1996 |
The effect of clinical outcome on platelet G proteins of major depressed patients.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Blood Platelets; Blotting, Western; Clomipramine; Depressive Disorder; Female; GTP-Binding Proteins; Humans; Imipramine; Male; Middle Aged; Paroxetine; Psychiatric Status Rating Scales; Signal Transduction; Treatment Outcome | 1998 |
Combined treatment with venlafaxine and tricyclic antidepressants in depressed patients who had partial response to clomipramine or imipramine: initial findings.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Clomipramine; Cyclohexanols; Depressive Disorder; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Imipramine; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Venlafaxine Hydrochloride | 2000 |
A prospective naturalistic study of 326 panic-agoraphobic patients treated with antidepressants.
Topics: Adult; Aged; Agoraphobia; Antidepressive Agents; Clomipramine; Demography; Female; Humans; Imipramine; Italy; Longitudinal Studies; Male; Middle Aged; Panic Disorder; Paroxetine; Patient Dropouts; Probability; Prospective Studies; Time Factors; Treatment Outcome | 2000 |
Comparative evaluation of two serotonin transporter ligands in the human brain: [(11)C](+)McN5652 and [(11)C]cyanoimipramine.
Topics: Adult; Brain; Carrier Proteins; Clomipramine; Humans; Imipramine; Injections, Intravenous; Isoquinolines; Ligands; Lung; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Organ Specificity; Radiopharmaceuticals; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Serotonin Plasma Membrane Transport Proteins; Tissue Distribution; Tomography, Emission-Computed; Whole-Body Counting | 2002 |
Nitric oxide involvement in depression during interferon-alpha therapy.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Female; Hepatitis C, Chronic; Humans; Imipramine; Interferon-alpha; Male; Nitrates; Nitric Oxide; Nitrites; Reference Values | 2003 |
253 other study(ies) available for imipramine and clomipramine
| Article | Year |
|---|---|
Novel analogs of tricyclic psychopharmacological agents.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chlorprothixene; Dihydroxyphenylalanine; Drug Interactions; Methamphetamine; Mice; Motor Activity; Serotonin | 1976 |
3-aminopyridazine derivatives with atypical antidepressant, serotonergic, and dopaminergic activities.
Topics: Animals; Antidepressive Agents; Chemical Phenomena; Chemistry; Dopamine Agents; Female; Mice; Pyridazines; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship | 1989 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Pyrroloisoquinoline antidepressants. 2. In-depth exploration of structure-activity relationships.
Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain; Catecholamines; Chemical Phenomena; Chemistry; Dopamine; Isoquinolines; Male; Molecular Conformation; Motor Activity; Norepinephrine; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Structure-Activity Relationship; Synaptosomes; Tetrabenazine | 1987 |
1-Aryl-2-(aminomethyl)cyclopropanecarboxylic acid derivatives. A new series of potential antidepressants.
Topics: Amino Acids; Animals; Antidepressive Agents; Behavior, Animal; Blepharoptosis; Cyclopropanes; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mice; Spectrophotometry, Infrared; Structure-Activity Relationship; Yohimbine | 1987 |
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship | 1981 |
Synthesis of pyridylallylamines related to zimelidine and their inhibition of neuronal monoamine uptake.
Topics: Animals; Biogenic Amines; Brain; Brompheniramine; Chemical Phenomena; Chemistry; In Vitro Techniques; Male; Mice; Molecular Conformation; Neurons; Norepinephrine; Pyridines; Serotonin; Structure-Activity Relationship; Zimeldine | 1981 |
Molecular modeling of phenothiazines and related drugs as multidrug resistance modifiers: a comparative molecular field analysis study.
Topics: Antineoplastic Agents; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Conformation; Phenothiazines; Thioxanthenes; Tumor Cells, Cultured | 1998 |
Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography.
Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Enzyme Inhibitors; Histamine H1 Antagonists; Micelles; Models, Biological; Norepinephrine; Rats; Receptors, Adrenergic, alpha-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Structure-Activity Relationship | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Inhibition of G protein-activated inwardly rectifying K+ channels by various antidepressant drugs.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Electrophysiology; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Proteins; Heart; Humans; Myocardium; Oocytes; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; RNA, Messenger; Xenopus laevis | 2004 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Antidepressant binding site in a bacterial homologue of neurotransmitter transporters.
Topics: Animals; Antidepressive Agents, Tricyclic; Bacteria; Binding Sites; Clomipramine; Crystallography, X-Ray; Drug Design; Kinetics; Models, Molecular; Plasma Membrane Neurotransmitter Transport Proteins; Protein Binding; Protein Conformation; Sequence Homology; Sodium | 2007 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics | 2012 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Synthesis and biological evaluation of novel 3,4-diaryl lactam derivatives as triple reuptake inhibitors.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Lactams; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Pyrrolidinones; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs.
Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Binding Sites; Drug Design; Ebolavirus; Glycoproteins; Models, Molecular; Protein Binding; Protein Conformation; Viral Proteins | 2018 |
Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain.
Topics: | 2022 |
Discovery of potent ebola entry inhibitors with (3S,4aS,8aS)-2-(3-amino-2-hydroxypropyl) decahydroisoquinoline-3-carboxamide scaffold.
Topics: Antiviral Agents; Ebolavirus; Hemorrhagic Fever, Ebola; HIV Fusion Inhibitors; Humans; Molecular Docking Simulation; Virus Internalization | 2022 |
Blood and brain concentrations of imipramine, clomipramine and their monomethylated metabolites after oral and intramuscular administration in rats.
Topics: Administration, Oral; Animals; Clomipramine; Desipramine; Dibenzazepines; Imipramine; Injections, Intramuscular; Male; Rats; Time Factors | 1977 |
Tricyclic antidepressant drugs as antagonists of muscarinic receptors in sympathetic ganglia.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Antidepressive Agents, Tricyclic; Cats; Clomipramine; Desipramine; Dimethylphenylpiperazinium Iodide; Ganglia, Autonomic; Ganglia, Spinal; Imipramine; Iprindole; Nictitating Membrane; Norepinephrine; Receptors, Cholinergic; Receptors, Muscarinic; Serotonin; Viloxazine | 1976 |
[The treatment of chronic pain symptoms with psychotropic drugs (author's transl)].
Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bone Diseases; Clomipramine; Drug Therapy, Combination; Haloperidol; Humans; Imipramine; Neoplasms; Neuralgia; Pain; Palliative Care; Promazine; Trimipramine | 1976 |
[Measurement of the electrophysiologic activity of monoaminergic neurons in rats].
Topics: Animals; Brain; Clomipramine; Electrophysiology; Imipramine; Male; Neurons; Norepinephrine; Rats; Serotonin | 1977 |
The effect of tricyclic antidepressants on corticofugal inhibition of the spinal trigeminal nucleus.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Brompheniramine; Cats; Cerebral Cortex; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Drug Combinations; Imipramine; Neural Inhibition; Procyclidine; Spinal Cord; Trigeminal Nerve | 1977 |
Some aspects of the psychopharmacological activity of maprotiline (Ludiomil): effects of single and repeated treatments.
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Anthracenes; Behavior, Animal; Body Temperature; Clomipramine; Depression, Chemical; Escape Reaction; Haplorhini; Head; Imipramine; Maprotiline; Mice; Muscle Contraction; Phenobarbital; Propranolol; Rats; Reserpine; Shrews | 1978 |
[The treatment of chronic low back pain with psychotropic drugs (author's transl)].
Topics: Antidepressive Agents; Back Pain; Central Nervous System; Chronic Disease; Clomipramine; Drug Therapy, Combination; Haloperidol; Humans; Imipramine; Methotrimeprazine; Peripheral Nerves; Psychotropic Drugs; Tranquilizing Agents | 1977 |
Intraalveolar foam cells associated with lipidosis-like alterations in lung and liver of rats treated with tricyclic psychotropic drugs.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chlorpromazine; Clomipramine; Dibenzocycloheptenes; Endoplasmic Reticulum; Female; Imipramine; Inclusion Bodies; Iprindole; Lipidoses; Liver; Macrophages; Male; Pulmonary Alveoli; Rats; Thioridazine | 1975 |
Retinal lipidosis in albino rats treated with chlorphentermine and with tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chlorphentermine; Clomipramine; Female; Imipramine; Inclusion Bodies; Iprindole; Male; Microscopy, Electron; Phagocytosis; Phentermine; Rats; Retina | 1976 |
Determination of chloroimipramine and its demethyl metabolite in plasma by ion-pair partition chromatography.
Topics: Alkanes; Butanols; Chromatography, Ion Exchange; Clomipramine; Desipramine; Dibenzazepines; Humans; Imipramine; Mesylates; Methyl Chloride | 1976 |
[The treatment of chronic pain with psychotropic drugs].
Topics: Clomipramine; Haloperidol; Humans; Imipramine; Methotrimeprazine; Muscle Contraction; Pain; Psychotropic Drugs; Receptors, Adrenergic, beta; Receptors, Dopamine | 1978 |
Enhancement of central norepinephrine and 5-hydroxytryptamine transmission by tricyclic antidepressants. A comparison.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cats; Clomipramine; Desipramine; Electric Stimulation; Female; Imipramine; Male; Norepinephrine; Serotonin; Stimulation, Chemical; Sympathetic Nervous System; Synaptic Transmission; Time Factors | 1979 |
Effects of drugs on hyperactivity and aggression induced by raphe lesions in rats.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Atropine; Brain Stem; Clomipramine; Desipramine; Humans; Imipramine; Male; Methyltyrosines; Motor Activity; Raphe Nuclei; Rats | 1978 |
Variations of chlorpromazine-related isosteres on the glycemic response in mice.
Topics: Adrenalectomy; Animals; Blood Glucose; Carbamazepine; Chlorpromazine; Clomipramine; Cyproheptadine; Hyperglycemia; Imipramine; Insulin; Islets of Langerhans; Male; Mice; Promazine | 1979 |
Seizure activity in photosensitive baboons following antidepressant drugs and the role of serotoninergic mechanisms.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Electroencephalography; Haplorhini; Imipramine; Isoquinolines; Maprotiline; Papio; Photic Stimulation; Seizures; Serotonin; Time Factors | 1977 |
The demethylation of imipramine and clomipramine as apparent from their plasma kinetics.
Topics: Administration, Oral; Adult; Biotransformation; Clomipramine; Dibenzazepines; Female; Half-Life; Humans; Imipramine; Injections, Intramuscular; Kinetics; Male; Methylation | 1977 |
Metabolism of 5-hydroxytryptamine and levels of tricyclic antidepressant drugs in rat brain after acute and chronic treatment.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Desipramine; Drug Administration Schedule; Imipramine; Male; Probenecid; Protriptyline; Rats; Serotonin | 1977 |
Effects of chronic imipramine and clomipramine oral administration on maternal behavior and litter development.
Topics: Animals; Body Weight; Clomipramine; Dibenzazepines; Female; Growth; Imipramine; Maternal Behavior; Motor Activity; Pregnancy; Rats; Time Factors | 1978 |
Influence of the new 5-HT-uptake inhibitor paroxetine on hypermotility in rats produced by p-chloroamphetamine (PCA) and 4,alpha-dimethyl-7-tyramine (H 77/77).
Topics: Amphetamines; Animals; Clomipramine; Dioxolanes; Drug Interactions; Female; Imipramine; Motor Activity; p-Chloroamphetamine; Piperidines; Rats; Serotonin; Time Factors; Tyramine | 1978 |
Relationship between surface activity and toxicity to Chang liver cultures of tricyclic antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Cells, Cultured; Clomipramine; Doxepin; Glucuronidase; Humans; Imipramine; L-Lactate Dehydrogenase; Liver; Nortriptyline; Surface Tension | 1979 |
High-affinity 3H-imipramine binding in rat cerebral cortex.
Topics: Amitriptyline; Animals; Binding Sites; Cerebral Cortex; Clomipramine; Desipramine; Imipramine; In Vitro Techniques; Male; Rats | 1979 |
Response to sleep deprivation as a predictor of therapeutic results with antidepressant drugs.
Topics: Antidepressive Agents, Tricyclic; Clomipramine; Depression; Female; Humans; Imipramine; Male; Maprotiline; Probability; Sleep Deprivation | 1979 |
Epileptic phenomena induced in the cat by the antidepressants maprotiline, imipramine, clomipramine, and amitriptyline.
Topics: Amitriptyline; Animals; Anthracenes; Cats; Cerebral Cortex; Clomipramine; Electroencephalography; Evoked Potentials; Female; Hippocampus; Imipramine; Male; Maprotiline; Reticular Formation; Seizures | 1979 |
A sensitive method for the simultaneous determination in biological fluids of imipramine and desipramine or clomipramine and N-desmethylclomipramine by gas chromatography mass spectrometry.
Topics: Chromatography, Gas; Clomipramine; Dealkylation; Desipramine; Humans; Imipramine; Mass Spectrometry; Methods | 1979 |
Failure of chronic lithium treatment to block tricyclic antidepressant-induced 5-HT supersensitivity.
Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Hippocampus; Imipramine; Lithium; Male; Pyramidal Tracts; Rats; Receptors, Serotonin | 1979 |
Hydroxylated metabolites of tricyclic antidepressants: preclinical assessment of activity.
Topics: Animals; Antidepressive Agents, Tricyclic; Biotransformation; Cerebral Cortex; Clomipramine; Desipramine; Hydroxylation; Imipramine; Male; Motor Activity; Norepinephrine; Rats; Reserpine; Serotonin; Synaptosomes; Tissue Distribution | 1979 |
Interaction studies between three antidepressant drugs (chlorimipramine, imipramine and zimelidine) and noradrenaline, tyramine and vagal stimulation on the heart rate and blood pressure in dogs.
Topics: Allylamine; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Blood Pressure; Clomipramine; Dogs; Drug Interactions; Electric Stimulation; Heart Rate; Imipramine; Norepinephrine; Pyridines; Tyramine; Vagus Nerve | 1979 |
Interaction studies between three antidepressant drugs (zimelidine, imipramine and chlorimipramine) and noradrenaline in healthy volunteers and some pharmacokinetics of the drugs studied.
Topics: Adult; Allylamine; Antidepressive Agents; Antidepressive Agents, Tricyclic; Blood Pressure; Chemical Phenomena; Chemistry; Clomipramine; Drug Interactions; Heart Rate; Humans; Imipramine; Male; Norepinephrine; Pyridines | 1979 |
Modulation of dopamine-mediated behavioural responses by antidepressants: effects of single and repeated treatment.
Topics: Amitriptyline; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Clomipramine; Dopamine; Humans; Hydroxydopamines; Imipramine; Male; Maprotiline; Rats; Rats, Inbred Strains; Stereotyped Behavior; Time Factors | 1979 |
Plasma levels of tricyclic antidepressants and clinical efficacy: review of the literature -- part II.
Topics: Antidepressive Agents, Tricyclic; Biotransformation; Clomipramine; Depression; Desipramine; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Doxepin; Drug Interactions; Humans; Imipramine; Maprotiline; Protriptyline | 1979 |
A simple method for the determination of therapeutic levels of clomipramine, imipramine and desipramine.
Topics: Chromatography, Thin Layer; Clomipramine; Desipramine; Dibenzazepines; Humans; Imipramine | 1977 |
Chemical, pharmacological and biochemical aspects of clomipramine. The binding of inhibitors of serotonin uptake to biological receptors.
Topics: Bridged Bicyclo Compounds; Bridged-Ring Compounds; Clomipramine; Dibenzazepines; Humans; Imipramine; Molecular Conformation; Receptors, Serotonin; Serotonin | 1977 |
[Hypersomnias. 1. Narcolepsy].
Topics: Amphetamines; Clomipramine; Humans; Imipramine; Methylphenidate; Monoamine Oxidase Inhibitors; Narcolepsy | 1977 |
Effect of tricyclic antidepressant drugs on spontaneous activity of noradrenergic neurons.
Topics: Action Potentials; Animals; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Electric Stimulation; Imipramine; Neurons; Norepinephrine; Rats; Synapses; Time Factors | 1978 |
[Convulsive incidents and EEG changes during treatment with tricyclic antidepressive agents].
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Electroencephalography; Epilepsy; Female; History of Medicine; Humans; Imipramine; Male; Middle Aged; Seizures | 1976 |
Serotonin accumulation by skeletal muscle.
Topics: Animals; Biological Transport; Chlorpheniramine; Chlorpromazine; Clomipramine; Dose-Response Relationship, Drug; Imipramine; Iprindole; Male; Muscles; Muscular Dystrophies; Procaine; Rats; Serotonin; Temperature; Urea | 1977 |
Tricyclic antidepressant drugs: attenuation of excitatory effects of d-lysergic acid diethylamide (LSD) on acoustic startle response.
Topics: Acoustic Stimulation; Animals; Antidepressive Agents, Tricyclic; Brain Chemistry; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Imipramine; Lysergic Acid Diethylamide; Male; Methyltyrosines; Rats; Reflex, Startle; Time Factors | 1977 |
Effects of several tricyclic antidepressants on the hemodynamics and myocardial contractility of the anesthetized dogs.
Topics: Animals; Antidepressive Agents, Tricyclic; Cardiac Output; Clomipramine; Desipramine; Dogs; Heart Rate; Hemodynamics; Imipramine; In Vitro Techniques; Myocardial Contraction; Time Factors | 1977 |
In vitro effect of suloctidil on 14C-5-hydroxytryptamine uptake and liberation in rat platelets.
Topics: Animals; Aspirin; Blood Platelets; Clomipramine; Dextroamphetamine; Fenfluramine; Imipramine; Kinetics; L-Lactate Dehydrogenase; Male; p-Chloroamphetamine; Propanolamines; Rats; Serotonin; Temperature | 1977 |
Studies on the mechanisms of L-dopa-induced depletion of 5-hydroxytryptamine in the mouse brain.
Topics: Amines; Animals; Benztropine; Biological Transport; Brain; Clomipramine; Cocaine; Dihydroxyphenylalanine; Dopamine; Imipramine; Levodopa; Male; Mice; Mice, Inbred ICR; Serotonin; Tryptophan | 1977 |
Effect of nomifensine on brain amines and epilepsy in photosensitive baboons.
Topics: Amines; Animals; Brain Chemistry; Clomipramine; Dose-Response Relationship, Drug; Imipramine; Isoquinolines; Maprotiline; Nomifensine; Papio; Photic Stimulation; Seizures | 1977 |
Effects of 4-methyl-alpha-ethyl-tyramine, 4, alpha-dimethyl-tyramine and tetrabenazine on the release and uptake of 5-hydroxytryptamine by human blood platelets in vitro.
Topics: Blood Platelets; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Humans; Imipramine; In Vitro Techniques; Serotonin; Temperature; Tetrabenazine; Time Factors; Tyramine | 1976 |
Comparison of the inhibition of 5-hydroxytryptamine uptake by methadone and its congeners in human platelets.
Topics: Blood Platelets; Clomipramine; Depression, Chemical; Humans; Imipramine; In Vitro Techniques; Kinetics; Methadone; Molecular Conformation; Serotonin | 1976 |
Investigation of the orthostatic reaction after intravenous administration of imipramine, chlorimipramine, and inimpramine-N-oxide.
Topics: Adult; Aged; Blood Pressure; Clomipramine; Depression; Dibenzazepines; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Imipramine; Injections, Intravenous; Male; Middle Aged | 1976 |
Effect of flupenthixol on depression with special reference to combination use with tricyclic antidepressants. An uncontrolled pilot study with 45 patients.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Clomipramine; Depression; Drug Evaluation; Drug Therapy, Combination; Female; Flupenthixol; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Pilot Projects; Thioxanthenes; Trimipramine | 1976 |
Thermoregulatory effects of monoamine potentiators and inhibitors in the rat.
Topics: Animals; Body Temperature Regulation; Clomipramine; Dibenzazepines; Dose-Response Relationship, Drug; Imipramine; Injections, Intraventricular; Male; Norepinephrine; Rats; Serotonin | 1976 |
[Psychotropic drugs and glaucoma (author's transl)].
Topics: Adult; Aged; Clomipramine; Depression; Desipramine; Dibenzocycloheptenes; Female; Fluphenazine; Glaucoma; Humans; Imipramine; Intraocular Pressure; Male; Middle Aged; Opipramol; Perazine; Psychotropic Drugs; Thiothixene; Tonometry, Ocular | 1976 |
The use of psychotropic drugs in the treatment of chronic, severe pains.
Topics: Chronic Disease; Clomipramine; Drug Evaluation; Drug Therapy, Combination; Haloperidol; Humans; Imipramine; Pain, Intractable; Psychotropic Drugs | 1976 |
The separation of some tricyclic antidepressants by high-performance liquid chromatography.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Desipramine; Imipramine; Microchemistry; Nortriptyline; Protriptyline; Trimipramine | 1976 |
Uptake of 14C-5-hydroxytryptamine by human and rat platelets and its pharmacological inhibition. A comparative kinetic analysis.
Topics: Adult; Animals; Blood Platelets; Clomipramine; Depression, Chemical; Fenfluramine; Humans; Imipramine; In Vitro Techniques; Kinetics; Male; Rats; Serotonin; Species Specificity | 1976 |
On the anticataleptic action of cyproheptadine.
Topics: Animals; Atropine; Catalepsy; Clomipramine; Cyproheptadine; Desipramine; Female; Fluphenazine; Humans; Imipramine; Male; Methyltyrosines; Pilocarpine; Pimozide; Promethazine; Rats; Reserpine; Spiperone | 1976 |
Effects of imipramine, chlorimipramine, and fluoxetine on cataplexy in dogs.
Topics: Animals; Cataplexy; Clomipramine; Dibenzazepines; Dogs; Female; Food; Humans; Imipramine; Male; Phenyl Ethers; Propylamines; Serotonin; Time Factors | 1976 |
Psychological medicine. Management of depression.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Clomipramine; Depression; Drug Interactions; Electroconvulsive Therapy; Female; Grief; Humans; Imipramine; Life Style; Lithium; Male; Phenelzine; Physician-Patient Relations; Recurrence; Social Isolation | 1975 |
[Antimitotic activity of some derivatives of imipramine].
Topics: Cells, Cultured; Clomipramine; Desipramine; Dibenzazepines; Humans; Imipramine; Lectins; Lymphocytes; Mitosis | 1975 |
Inhibition of prostaglandin synthetase by psychotropic drugs.
Topics: Amitriptyline; Animals; Anthracenes; Antidepressive Agents; Arachidonic Acids; Cattle; Chlorpromazine; Clomipramine; Desipramine; Enzyme Inhibitors; Haloperidol; Imipramine; Male; Mixed Function Oxygenases; Prostaglandins; Psychotropic Drugs; Seminal Vesicles | 1975 |
[Effect of prothixen and related compounds on serotonin absorption by human thrombocytes].
Topics: Absorption; Amitriptyline; Biological Transport; Blood Platelets; Cell Membrane Permeability; Chlorpromazine; Clomipramine; Depression, Chemical; Desipramine; Humans; Imipramine; In Vitro Techniques; Nortriptyline; Serotonin; Structure-Activity Relationship; Thioxanthenes; Triazines | 1975 |
Measurement of clomipramine, N-desmethyl-clomipramine, imipramine, and dehydroimipramine in biological fluids by selective ion monitoring, and pharmacokinetics of clomipramine.
Topics: Antidepressive Agents; Clomipramine; Dibenzazepines; Evaluation Studies as Topic; Gas Chromatography-Mass Spectrometry; Humans; Imipramine; Regression Analysis; Time Factors | 1976 |
Central monoaminergic mechanisms in mice and analgesic activity of spiradoline mesylate, a selective kappa-opioid receptor agonist.
Topics: Analgesics; Animals; Brain; Clomipramine; Desipramine; Fenclonine; Imipramine; Male; Mice; Mice, Inbred ICR; Morphine; Norepinephrine; Phenoxybenzamine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Reserpine; Serotonin | 1992 |
Effect of prenatal exposure to tianeptine on different neurotransmitter receptors and 5-HT-stimulated inositol phosphate formation in rat brain.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Female; Imipramine; Inositol Phosphates; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Dopamine D2; Receptors, Neurotransmitter; Receptors, Serotonin; Serotonin; Thiazepines | 1992 |
Binding of tricyclic antidepressant drugs to trophozoites of Giardia lamblia.
Topics: Animals; Binding Sites; Binding, Competitive; Clomipramine; Giardia lamblia; Hydrogen-Ion Concentration; Imipramine; Indicators and Reagents; Kinetics; Protozoan Proteins; Subcellular Fractions; Temperature | 1992 |
Tricyclic antidepressant plasma levels after fluoxetine addition.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged | 1992 |
Effects of chronic variable stress and antidepressant drugs on behavioral inactivity during an uncontrollable stress: interaction between both treatments.
Topics: Animals; Antidepressive Agents; Arousal; Clomipramine; Desipramine; Escape Reaction; Helplessness, Learned; Imipramine; Motor Activity; Phenelzine; Rats; Stress, Psychological | 1992 |
Persistent impairment of clomipramine demethylation in recently detoxified alcoholic patients.
Topics: Adult; Alcoholism; Clomipramine; Dealkylation; Desipramine; Female; Humans; Hydroxylation; Imipramine; Male; Middle Aged; Models, Biological | 1992 |
Painful ejaculation associated with antidepressants in four patients.
Topics: Adult; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Ejaculation; Humans; Imipramine; Male; Middle Aged; Pain; Panic Disorder | 1991 |
Higher postdexamethasone serum cortisol levels in agoraphobic than in nonagoraphobic panic disorder patients.
Topics: Adult; Agoraphobia; Clomipramine; Dexamethasone; Diagnosis, Differential; Female; Humans; Hydrocortisone; Imipramine; Male; Panic Disorder; Psychiatric Status Rating Scales | 1991 |
[Antiprotozoal effects of benzodiazepine derivatives].
Topics: Animals; Benzodiazepines; Chlorpromazine; Clomipramine; Crithidia; Desipramine; Eukaryota; Imipramine; Leishmania mexicana; Metronidazole; Trichomonas vaginalis; Trypanosoma cruzi | 1990 |
Why some depressed patients may have low platelet 3H-imipramine binding.
Topics: Antidepressive Agents; Blood Platelets; Carrier Proteins; Cell Membrane; Clomipramine; Depressive Disorder; Humans; Imipramine; Paroxetine; Piperidines; Receptors, Drug; Receptors, Neurotransmitter; Serotonin Antagonists | 1990 |
Tricyclic antidepressants, thyroid function, and their relationship with the behavioral responses in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Arousal; Avoidance Learning; Clomipramine; Conditioning, Classical; Desipramine; Diabetes Mellitus, Experimental; Escape Reaction; Helplessness, Learned; Imipramine; Male; Rats; Rats, Inbred Strains; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1990 |
[Too weak with laughing].
Topics: Adult; Cataplexy; Clomipramine; Emotions; Female; Humans; Imipramine; Male; Methylphenidate; Middle Aged; Narcolepsy; Paralysis | 1990 |
Post-mortem drug redistribution--a toxicological nightmare.
Topics: Adult; Amobarbital; Barbiturates; Clomipramine; Doxepin; Female; Flurazepam; Humans; Imipramine; Male; Middle Aged; Pentobarbital; Postmortem Changes; Secobarbital; Suicide; Tissue Distribution | 1990 |
Inhibition of fast axonal transport in bullfrog nerves by dibenzazepine and dibenzocycloheptadiene calmodulin inhibitors.
Topics: Acetylcholinesterase; Adenosine Triphosphate; Amitriptyline; Animals; Axonal Transport; Calmodulin; Clomipramine; Desipramine; Ganglia, Spinal; Imipramine; In Vitro Techniques; Microtubules; Phosphocreatine; Rana catesbeiana; Spinal Nerves | 1986 |
Helpless behavior (escape deficits) in streptozotocin-diabetic rats: resistance to antidepressant drugs.
Topics: Animals; Antidepressive Agents; Brain; Clenbuterol; Clomipramine; Conditioning, Operant; Desipramine; Diabetes Mellitus, Experimental; Electroshock; Escape Reaction; Helplessness, Learned; Imipramine; Insulin; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Triiodothyronine | 1989 |
[Evaluation of the central anticholinergic activity of antidepressants. Comparison of two experimental methods].
Topics: Animals; Antidepressive Agents, Tricyclic; Atropine; Clomipramine; Dibenzazepines; Female; Guinea Pigs; Imipramine; Male; Mice; Mice, Inbred Strains; Oxotremorine; Parasympatholytics; Tremor | 1989 |
Jerk-locked averaging and somatosensory evoked potential in tricyclic-induced myoclonus: a case report.
Topics: Adult; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials, Somatosensory; Female; Humans; Imipramine; Myoclonus; Signal Processing, Computer-Assisted | 1989 |
Cytostatic activity of commonly used tricyclic antidepressants.
Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Clomipramine; Drug Screening Assays, Antitumor; Imipramine; Mechlorethamine; Tumor Cells, Cultured | 1989 |
High blood concentrations of imipramine or clomipramine and therapeutic failure: a case report study using drug monitoring data.
Topics: Aged; Clomipramine; Debrisoquin; Depressive Disorder; Female; Humans; Hydroxylation; Imipramine; Middle Aged; Monitoring, Physiologic; Phenotype; Psychiatric Status Rating Scales | 1989 |
Effect of tricyclic antidepressant drugs in the isolation-induced social behavioural deficit test.
Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Desipramine; Imipramine; Male; Mice; Mice, Inbred Strains; Motor Activity; Reference Values; Social Behavior; Social Isolation | 1989 |
Species dependence of adaptations at the pre- and postsynaptic serotonergic receptors following long-term antidepressant drug treatment.
Topics: Adaptation, Physiological; Amitriptyline; Animals; Antidepressive Agents; Brain; Clomipramine; Imipramine; Male; Mianserin; Rabbits; Rats; Rats, Inbred Strains; Receptors, Serotonin; Synaptic Transmission | 1988 |
Chronic administration of tricyclic antidepressants suppresses hypothalamo-pituitary-adrenocortical activity in male rats.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Corticosterone; Desipramine; Dexamethasone; Dose-Response Relationship, Drug; Hypothalamo-Hypophyseal System; Imipramine; Male; Pituitary-Adrenal System; Rats; Rats, Inbred Strains | 1988 |
Impaired response of experimental diabetic mice to tricyclics: a possible beta-adrenergic mechanism.
Topics: Animals; Clenbuterol; Clomipramine; Desipramine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hypothermia, Induced; Imipramine; Male; Mice; Motor Activity; Receptors, Adrenergic, beta; Thyroxine; Triiodothyronine | 1988 |
Relationship between growth inhibition and mitochondrial function in petite-negative yeasts. II. Effects of central nervous system drugs upon pathogenic and non-pathogenic Candida species.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Candida; Cell Division; Chlorpheniramine; Chlorpromazine; Clomipramine; Cytochromes; Electrophoresis, Polyacrylamide Gel; Imipramine; Mitochondria; Oxygen Consumption; Promazine | 1985 |
Influence of neuroleptics on the metabolism of tricyclic antidepressants--in vitro experiments with rat liver microsomes.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clomipramine; Drug Interactions; Female; Haloperidol; Imipramine; In Vitro Techniques; Microsomes, Liver; Perazine; Rats; Rats, Inbred Strains | 1986 |
Effect of tricyclic drugs on mitochondrial membrane.
Topics: Adenosine Triphosphatases; Animals; Antidepressive Agents, Tricyclic; Chlorpromazine; Clomipramine; Imipramine; In Vitro Techniques; Intracellular Membranes; Male; Mitochondria, Liver; Oxygen Consumption; Permeability; Potassium; Promethazine; Rats | 1985 |
Effects of tricyclic antidepressant drugs on energy-linked reactions in mitochondria.
Topics: Adenosine Triphosphatases; Animals; Antidepressive Agents, Tricyclic; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cattle; Chromaffin Granules; Clomipramine; Energy Metabolism; Imipramine; In Vitro Techniques; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; NAD; Rats; Submitochondrial Particles | 1986 |
High- and low-affinity binding of [3H]imipramine in rat hypothalamus.
Topics: Amitriptyline; Animals; Citalopram; Clomipramine; Cyclopropanes; Hypothalamus; Imipramine; Kinetics; Male; Milnacipran; Paroxetine; Piperidines; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Sodium | 1986 |
Chlorimipramine--but not imipramine--rapidly reduces imipramine--but not paroxetine--binding in human platelets.
Topics: Blood Platelets; Clomipramine; Humans; Imipramine; Iodine; Paroxetine; Piperidines; Serotonin; Tritium | 1986 |
Pharmacological manipulation of sexual behaviour in stallions.
Topics: Animals; Clomipramine; Diazepam; Ejaculation; Fenclonine; Horses; Imipramine; Male; Naloxone; Penile Erection; Pituitary Hormone-Releasing Hormones; Sexual Behavior, Animal; Yohimbine | 1987 |
Cardiovascular effects of paroxetine, a newly developed antidepressant, in anesthetized dogs in comparison with those of imipramine, amitriptyline and clomipramine.
Topics: Amitriptyline; Anesthesia; Animals; Antidepressive Agents; Atrioventricular Node; Blood Pressure; Clomipramine; Dogs; Electrocardiography; Female; Heart Conduction System; Heart Rate; Hemodynamics; Imipramine; Male; Paroxetine; Piperidines; Respiration | 1987 |
The effect of antidepressant drugs on 24-hour rhythms of tryptophan metabolism in the rat.
Topics: Administration, Oral; Animals; Antidepressive Agents; Circadian Rhythm; Clomipramine; Imipramine; Male; Rats; Rats, Inbred Strains; Time Factors; Tryptophan; Zimeldine | 1985 |
Dissociation kinetics of [3H]paroxetine binding to rat brain consistent with a single-site model of the antidepressant binding/5-hydroxytryptamine uptake site.
Topics: Animals; Brain; Cell Membrane; Citalopram; Clomipramine; Imipramine; Kinetics; Male; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Zimeldine | 1988 |
Differential effects of long-term antidepressant treatments on 8-OHDPAT-induced increases in plasma prolactin and corticosterone in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Clomipramine; Clorgyline; Corticosterone; Imipramine; Male; Naphthalenes; Prolactin; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes; Time Factors | 1988 |
[Direct interaction of tricyclic antidepressants with opiate binding sites in the bovine adrenal medulla].
Topics: Adrenal Medulla; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cattle; Clomipramine; Cyproheptadine; Imipramine; Kinetics; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1986 |
Changes in [3H]5-HT uptake and [3H]imipramine binding in platelets after chlorimipramine in healthy volunteers. Comparison with maprotiline and amineptine.
Topics: Adult; Blood Platelets; Carrier Proteins; Clomipramine; Dibenzocycloheptenes; Female; Humans; Imipramine; Kinetics; Male; Maprotiline; Middle Aged; Receptors, Drug; Receptors, Neurotransmitter; Serotonin | 1987 |
Fengabine, a novel antidepressant GABAergic agent. I. Activity in models for antidepressant drugs and psychopharmacological profile.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Bicuculline; Chlorophenols; Clomipramine; Depressive Disorder; Disease Models, Animal; gamma-Aminobutyric Acid; Imipramine; Male; Olfactory Bulb; Rats; Receptors, GABA-A; Seizures; Sleep | 1987 |
Comparison of the metabolism of the three antidepressants amitriptyline, imipramine, and chlorimipramine in vitro in rat liver microsomes.
Topics: Amitriptyline; Animals; Chemical Phenomena; Chemistry; Clomipramine; Female; Hydroxylation; Imipramine; In Vitro Techniques; Methylation; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1986 |
Triiodothyroacetic acid (TRIAC) potentiation of antidepressant-induced reversal of learned helplessness in rats.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Clomipramine; Drug Synergism; Electroshock; Helplessness, Learned; Imipramine; Male; Penbutolol; Rats; Rats, Inbred Strains; Triiodothyronine | 1988 |
High levels of tricyclic antidepressants in conventional therapy: determinant factors.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline; Risk Factors | 1988 |
Inhibition of sodium-dependent [3H]imipramine binding in rat brain by serotonin and serotonin uptake inhibitors.
Topics: Animals; Cell Membrane; Cerebral Cortex; Clomipramine; Fluoxetine; Imipramine; Male; Rats; Receptors, Serotonin; Serotonin; Sodium; Trazodone | 1988 |
Selectivity in the binding of psychotropic drugs to the variants of alpha-1 acid glycoprotein.
Topics: Amitriptyline; Clomipramine; Desipramine; Hydrogen-Ion Concentration; Imipramine; Maprotiline; Methadone; Orosomucoid; Psychotropic Drugs; Thioridazine; Trimipramine | 1988 |
Thyroid function and reversal by antidepressant drugs of depressive-like behavior (escape deficits) in rats.
Topics: Animals; Antidepressive Agents; Brain; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Escape Reaction; Hypothyroidism; Imipramine; Male; Nialamide; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroid Gland; Triiodothyronine | 1987 |
Receptor assay based on 3H-imipramine binding.
Topics: Antidepressive Agents; Binding, Competitive; Blood Platelets; Chromatography, Thin Layer; Citalopram; Clomipramine; Humans; Imipramine; Propylamines; Radioligand Assay | 1987 |
Cyproheptadine and antidepressant-induced anorgasmia.
Topics: Adult; Clomipramine; Cyproheptadine; Depressive Disorder; Female; Humans; Imipramine; Sexual Dysfunction, Physiological | 1986 |
Subdivision of mouse brain [3H]imipramine binding based on ion dependence and serotonin sensitivity.
Topics: Animals; Binding Sites; Brain; Chromatography, High Pressure Liquid; Clomipramine; Desipramine; Imipramine; Kinetics; Mice; Potassium Chloride; Serotonin; Sodium Chloride; Synaptosomes; Tissue Distribution | 1986 |
The lesion of serotonergic neurons does not prevent antidepressant-induced reversal of escape failures produced by inescapable shocks in rats.
Topics: Animals; Antidepressive Agents; Clomipramine; Desipramine; Helplessness, Learned; Imipramine; Male; Nialamide; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin | 1986 |
Chlorimipramine--but not imipramine--rapidly reduces [3H]imipramine binding in human platelet membranes.
Topics: Amitriptyline; Blood Platelets; Cell Membrane; Clomipramine; Depressive Disorder; Humans; Imipramine; In Vitro Techniques; Kinetics | 1986 |
[Effects of tricyclic antidepressants on sleep polygraphy].
Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Clomipramine; Humans; Imipramine; Male; Sleep; Sleep, REM | 1985 |
5-Hydroxytryptamine uptake and imipramine binding sites in neurotumor NCB-20 cells.
Topics: Animals; Binding Sites; Brain; Clomipramine; Cricetinae; Cricetulus; Desipramine; Fluoxetine; Hybrid Cells; Imipramine; Iprindole; Kinetics; Mianserin; Neuroblastoma; Opipramol; Rats; Serotonin | 1985 |
Some effects of chlorimipramine and imipramine on the schedule-controlled behavior of the pigeon.
Topics: Animals; Chlorpromazine; Clomipramine; Columbidae; Conditioning, Psychological; Imipramine; Male; Punishment; Structure-Activity Relationship | 1985 |
Antidepressant drugs suppress growth of the human pathogenic protozoan Giardia lamblia.
Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Giardia; Imipramine | 1985 |
Ornade and anticholinergic toxicity: hypertension, hallucinations, and arrhythmias.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Chlorpheniramine; Clomipramine; Dibenzazepines; Drug Combinations; Electrocardiography; Female; Hallucinations; Humans; Hypertension; Imipramine; Male; Phenylpropanolamine; Quaternary Ammonium Compounds | 1974 |
Lipidosis-like ultrastructural alterations in rat lymph nodes after treatment with tricyclic antidepressants or neuroleptics.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chlorpromazine; Clomipramine; Dibenzocycloheptenes; Female; Imipramine; Inclusion Bodies; Iprindole; Lipidoses; Lymph Nodes; Lymphocytes; Male; Microscopy, Electron; Rats; Thioridazine | 1974 |
[Problems of differentiated thymoleptic therapy in phasic depressions].
Topics: Adolescent; Adult; Amitriptyline; Anthracenes; Antidepressive Agents; Azocines; Benzoates; Benzofurans; Bipolar Disorder; Clomipramine; Cyclothymic Disorder; Depression; Dibenzazepines; Dimethylamines; Dothiepin; Humans; Imipramine; Methylamines; Middle Aged; Personality Disorders; Propylamines; Schizophrenia | 1974 |
A technique for surveying side-effects of tricyclic drugs with reference to reported sexual effects.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Drug Evaluation; Erectile Dysfunction; Female; Humans; Imipramine; Libido; Male; Middle Aged; Orgasm; Sexual Behavior; Surveys and Questionnaires | 1973 |
[Comparative effects of various antidepressants on the response to noradrenaline of the deferent canal and the arterial pressure, and the response to 5-hydroxytryptamine of the rat uterus].
Topics: Amitriptyline; Animals; Antidepressive Agents; Blood Pressure; Carotid Arteries; Clomipramine; Dibenzazepines; Dose-Response Relationship, Drug; Drug Interactions; Female; Imipramine; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Orphenadrine; Quinuclidines; Rats; Serotonin; Uterus; Vas Deferens | 1974 |
[3H]Imipramine binding and [3H]5HT uptake in human blood platelets: changes after one week chlorimipramine treatment.
Topics: Adult; Blood Platelets; Carrier Proteins; Clomipramine; Female; Humans; Imipramine; In Vitro Techniques; Kinetics; Male; Middle Aged; Receptors, Drug; Receptors, Neurotransmitter; Serotonin; Tritium | 1984 |
Dexamethasone suppression test identifies subtypes of depression which respond to different antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Depression; Depression, Chemical; Desipramine; Dexamethasone; Diagnosis, Differential; Female; Humans; Imipramine; Male; Pituitary-Adrenal System | 1980 |
Therapeutic drug monitoring of psychotropic drugs in children.
Topics: Adolescent; Adult; Age Factors; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Child; Child, Preschool; Chlorpromazine; Clomipramine; Dose-Response Relationship, Drug; Half-Life; Haloperidol; Humans; Imipramine; Kinetics; Mental Disorders; Nortriptyline | 1983 |
Tricyclic antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Dopamine; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Imipramine; Male; Rats; Receptors, Dopamine; Time Factors | 1980 |
Some neuropharmacological effects of Ro 11-2465--a novel tricyclic antidepressant with potent inhibitory activity on the uptake of 5-HT.
Topics: Animals; Behavior, Animal; Blood Platelets; Brain; Clomipramine; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Imipramine; Male; Norepinephrine; Rats; Serotonin; Serotonin Antagonists | 1982 |
Cardiovascular and anticholinergic effects of zimelidine.
Topics: Amitriptyline; Animals; Antidepressive Agents; Blood Pressure; Brompheniramine; Clomipramine; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Imipramine; Male; Pyridines; Receptors, Cholinergic; Zimeldine | 1982 |
Distal colon motility as a predictor of antidepressant response to fenfluramine, imipramine and clomipramine.
Topics: Adolescent; Adult; Clomipramine; Colon; Depressive Disorder; Double-Blind Method; Female; Fenfluramine; Gastrointestinal Motility; Humans; Imipramine; Male; Middle Aged | 1983 |
[Effect of chronic administration of antidepressants on the binding of 3H-imipramine with mouse brain synaptic membranes].
Topics: Animals; Antidepressive Agents; Brain; Clomipramine; Imipramine; Male; Mice; Morphine Derivatives; Synaptic Membranes; Time Factors; Zimeldine | 1983 |
Withdrawal-like behaviour induced by inhibitors of biogenic amine reuptake in rats treated chronically with delta 9-tetrahydrocannabinol.
Topics: Animals; Biogenic Amines; Body Weight; Clomipramine; Dronabinol; Eating; Fluoxetine; Humans; Imipramine; Male; Rats; Substance Withdrawal Syndrome; Time Factors | 1980 |
Sensitivity in vivo of central alpha 2- and opiate receptors after chronic treatment with various antidepressants.
Topics: Animals; Antidepressive Agents; Brompheniramine; Chlorpromazine; Clomipramine; Clonidine; Desipramine; Evoked Potentials; Imipramine; Iprindole; Locus Coeruleus; Male; Mianserin; Morphine; Neural Inhibition; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Opioid; Zimeldine | 1982 |
Drug-specificity in the perturbation of pulmonary disposition of serotonin in rabbit in vivo.
Topics: Animals; Chlorpromazine; Clomipramine; Imipramine; Lung; Male; Propranolol; Rabbits; Radioisotope Dilution Technique; Serotonin | 1983 |
Relevance of tryptophan and tyrosine availability in endogenous and 'non-endogenous' depressives treated with imipramine or clomipramine.
Topics: Biological Availability; Clomipramine; Depression; Depressive Disorder; Humans; Imipramine; Time Factors; Tryptophan; Tyrosine | 1981 |
Antidepressants cause lethal disruption of membrane function in the human protozoan parasite Leishmania.
Topics: Animals; Cell Membrane; Clomipramine; Humans; Imipramine; Leishmania; Mice; Mice, Inbred BALB C; Proline; Species Specificity | 1984 |
Biological markers in obsessive-compulsive and affective disorders.
Topics: Blood Platelets; Clomipramine; Clonidine; Depressive Disorder; Dexamethasone; Electroencephalography; Growth Hormone; Humans; Hydrocortisone; Imipramine; Obsessive-Compulsive Disorder; Sleep | 1984 |
[Narcolepsy--epilepsy. Differential diagnosis].
Topics: Amnesia; Cataplexy; Clomipramine; Diagnosis, Differential; Electroencephalography; Epilepsy; Hallucinations; Humans; Imipramine; Narcolepsy | 1984 |
[N-dealkylation of chlorimipramine and chlorpromazine in patients undergoing chronic treatment with both drugs: preliminary results].
Topics: Chlorpromazine; Clomipramine; Depression; Dissociative Disorders; Humans; Imipramine | 1984 |
[A microanalytical gas liquid chromatography method with a nitrogen-phosphorus detector in the assay of various psychotropic drugs of tricyclic structure and of their N-demethylated metabolites].
Topics: Chlorpromazine; Chromatography, Gas; Clomipramine; Humans; Imipramine; Microchemistry; Nitrogen; Phosphorus | 1984 |
High-performance liquid chromatographic determination of imipramine and desipramine in human serum.
Topics: Chromatography, High Pressure Liquid; Clomipramine; Desipramine; Humans; Imipramine | 1984 |
Simultaneous measurement of various antidepressants in the plasma of depressed patients by high performance liquid chromatography.
Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents; Chromatography, High Pressure Liquid; Clomipramine; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Imipramine; Male; Maprotiline; Middle Aged; Nortriptyline | 1984 |
Artefactual inhibition of dopamine uptake by psychotropic drugs on striatal synaptosomal preparation.
Topics: Animals; Antidepressive Agents; Clomipramine; Corpus Striatum; Dopamine; Imipramine; In Vitro Techniques; Male; Psychotropic Drugs; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes | 1984 |
Tricyclic antidepressant drugs and individual differences in the exploratory activity of rats: contrasting effects of tertiary and secondary amine compounds.
Topics: Amines; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Exploratory Behavior; Female; Imipramine; Protriptyline; Rats; Structure-Activity Relationship | 1980 |
Antidepressants and serotonin neurons of the raphe.
Topics: Animals; Antidepressive Agents, Tricyclic; Benzofurans; Brain Stem; Citalopram; Clomipramine; Ethers; Fluvoxamine; Imipramine; Indoles; Locus Coeruleus; Male; Microscopy, Fluorescence; Norepinephrine; Oximes; Piperidines; Propylamines; Raphe Nuclei; Rats; Receptors, Serotonin; Serotonin | 1981 |
Column deactivation in analysis for underivatized tricyclic antidepressants by gas chromatography with use of a nitrogen detector.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Desipramine; Humans; Imipramine; Nitrogen; Nortriptyline | 1983 |
Complex inhibition of [3H]imipramine binding by serotonin and nontricyclic serotonin uptake blockers.
Topics: Amitriptyline; Animals; Binding, Competitive; Cerebral Cortex; Clomipramine; Desipramine; Imipramine; Male; Nortriptyline; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists | 1983 |
Subcellular distribution of high affinity [3H]imipramine binding and [3H]serotonin uptake in rat brain.
Topics: Animals; Brain; Clomipramine; Imipramine; In Vitro Techniques; Kinetics; Microsomes; Mitochondria; Rats; Serotonin; Subcellular Fractions; Synaptosomes | 1983 |
Failure of physostigmine in intoxications with tricyclic antidepressants in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Atropine; Clomipramine; Desipramine; Drug Interactions; Female; Heart Rate; Imipramine; Lethal Dose 50; Physostigmine; Rats; Rats, Inbred Strains; Respiration; Time Factors | 1982 |
On the kinetics of imipramine and related antidepressants.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Desipramine; Half-Life; Humans; Imipramine; Kinetics; Rats | 1980 |
Pituitary-adrenal disinhibition in depression: marker of a subtype with characteristic clinical features and response to treatment?
Topics: Adult; Amitriptyline; Clomipramine; Depressive Disorder; Desipramine; Dexamethasone; Female; Humans; Hydrocortisone; Imipramine; Male; Middle Aged; Pituitary-Adrenal System; Recurrence | 1981 |
Antidepressants and the control of predatory behavior.
Topics: Animals; Appetitive Behavior; Clomipramine; Dose-Response Relationship, Drug; Ferrets; Fluoxetine; Imipramine; Male; Predatory Behavior; Propylamines; Reaction Time | 1980 |
[Comparative studies of the nitrosation behavior of drugs by constant pH value and under simulated stomach conditions].
Topics: Aminopyrine; Ampicillin; Biotransformation; Clomipramine; Desipramine; Dipyrone; Ethambutol; Gastric Acidity Determination; Gastric Mucosa; Humans; Imipramine; Neoplasms; Nitrites; Nitroso Compounds; Oxacillin; Penicillins; Piperazines | 1982 |
Tricyclic antidepressants and monoamine oxidase inhibitors in the treatment of agoraphobia.
Topics: Agoraphobia; Antidepressive Agents, Tricyclic; Clomipramine; Diazepam; Double-Blind Method; Humans; Imipramine; Monoamine Oxidase Inhibitors; Panic; Phenelzine; Phobic Disorders | 1982 |
[Pressor response to the stimulation of peripheral sympathetic nerves and the posterior hypothalamus in the presence of tricyclic antidepressive agents and nomifensine in dogs].
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Clomipramine; Dogs; Electric Stimulation; Hypothalamus; Hypothalamus, Posterior; Imipramine; Isoquinolines; Nomifensine; Peripheral Nerves | 1982 |
The effects of antidepressants on aggressiveness induced by social deprivation in mice.
Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Humans; Imipramine; Maprotiline; Mice; Social Isolation | 1981 |
[Atypical antidepressants: effect on synaptosomal uptake of serotonin and GABA].
Topics: Animals; Antidepressive Agents; Brain; Carbazoles; Carbolines; Clomipramine; Depression, Chemical; Desipramine; gamma-Aminobutyric Acid; Imipramine; In Vitro Techniques; Oxazines; Piperazines; Rats; Serotonin; Synaptosomes; Trazodone | 1981 |
Determination of clomipramine or imipramine and their mono-demethylated metabolites in human blood or plasma by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Clomipramine; Humans; Imipramine | 1981 |
The dexamethasone suppression test in the identification subtypes of depression differentially responsive to antidepressants [proceedings].
Topics: Adult; Age Factors; Aged; Amitriptyline; Clomipramine; Depressive Disorder; Desipramine; Dexamethasone; Female; Humans; Hydrocortisone; Imipramine; Male; Middle Aged; Radioimmunoassay; Statistics as Topic | 1981 |
Is Ro 11-2465 (cyan-imipramine) an antagonist of postsynaptic serotonin receptors?
Topics: Amitriptyline; Animals; Clomipramine; Hindlimb; Imipramine; Lysergic Acid Diethylamide; Male; Quipazine; Rats; Rats, Inbred Strains; Reflex; Serotonin Antagonists; Spinal Cord | 1981 |
[Correlation between antidepressant membrane affinity and their effects on neuromediator reuptake].
Topics: Affinity Labels; Antidepressive Agents; Carbazoles; Clomipramine; Desipramine; Imipramine; Liposomes; Membrane Lipids; Phospholipids; Piperazines | 1981 |
Antidepressants inhibit enkephalin binding to synaptosome-enriched fractions of rat brain.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Imipramine; Male; Nortriptyline; Rats; Rats, Inbred Strains; Synaptosomes; Viloxazine | 1981 |
The effects of tricyclic antidepressants on performance under a differential-reinforcement-of-low-rates schedule in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Clomipramine; Conditioning, Operant; Desipramine; Dose-Response Relationship, Drug; Imipramine; Male; Rats; Reinforcement Schedule; Scopolamine | 1980 |
Hyposensitivity of dopamine "autoreceptors" induced by chronic administration of tricyclic antidepressants.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents, Tricyclic; Apomorphine; Caudate Nucleus; Clomipramine; Corpus Striatum; Dopamine; Imipramine; Male; Motor Activity; Rats; Receptors, Dopamine | 1980 |
The WHO Depression Scale. Relationship to the Newcastle Scales.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Clomipramine; Depressive Disorder; Female; Humans; Imipramine; Male; Middle Aged; Psychiatric Status Rating Scales; World Health Organization | 1980 |
Specific binding of [3H]imipramine indicates the presence of a specific serotonin transport system on endothelial cells of porcine brain.
Topics: Animals; Binding, Competitive; Blood-Brain Barrier; Brain; Carrier Proteins; Clomipramine; Dose-Response Relationship, Drug; Endothelium; Imipramine; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Serotonin Plasma Membrane Transport Proteins; Swine | 1995 |
Behavioural profile of two potential antidepressant pyridazine derivatives including arylpiperazinyl moieties in their structure, in mice.
Topics: 5-Hydroxytryptophan; Analgesia; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Blepharoptosis; Citalopram; Clomipramine; Drug Interactions; Fluoxetine; Hypothermia; Imipramine; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Models, Molecular; Motor Activity; Naloxone; Piperazines; Pyridazines; Reserpine; Structure-Activity Relationship; Swimming; Trazodone; Yohimbine | 1995 |
Drugs and breast milk.
Topics: Atenolol; Breast Feeding; Central Nervous System; Clomipramine; Female; Humans; Imipramine; Infant; Infant, Newborn; Male; Milk, Human | 1995 |
Differential effects of chronic antidepressant treatment on 5-HT1C receptor binding sites in Wistar rat brain.
Topics: Animals; Brain; Clomipramine; Clorgyline; Ergolines; Imipramine; Male; Rats; Rats, Wistar; Receptors, Serotonin | 1994 |
REM sleep deprivation potentiates the effects of imipramine and desipramine but not that of clomipramine in the forced swimming test.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Brain; Clomipramine; Desipramine; Imipramine; Male; Mice; Receptors, Adrenergic, alpha; Sleep Deprivation; Sleep, REM; Swimming; Yohimbine | 1993 |
Surface ionization organic mass spectrometry of imipramine, desipramine, clomipramine, and lidocaine.
Topics: Clomipramine; Desipramine; Humans; Imipramine; Lidocaine; Mass Spectrometry; Sensitivity and Specificity; Surface Properties | 1994 |
The origin of excessive daytime sleepiness in the Prader-Willi syndrome.
Topics: Adolescent; Adult; Catalepsy; Clomipramine; Female; Humans; Hypoventilation; Imipramine; Male; Middle Aged; Narcolepsy; Polysomnography; Prader-Willi Syndrome; Sleep Apnea Syndromes; Sleep, REM; Sodium Oxybate | 1993 |
Sexual dysfunction during antidepressant treatment.
Topics: Adult; Ambulatory Care; Antidepressive Agents; Anxiety Disorders; Clomipramine; Depressive Disorder; Female; Fluoxetine; Humans; Imipramine; Incidence; Male; Middle Aged; Orgasm; Pain; Patient Compliance; Retrospective Studies; Sexual Dysfunctions, Psychological | 1993 |
Attenuation of hypercortisolemia in fawn-hooded rats by antidepressant drugs.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Antidepressive Agents; Clomipramine; Clorgyline; Corticosterone; Imipramine; Male; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Species Specificity | 1993 |
Effects of antidepressant drug treatment on levels of NPY or prepro-NPY-mRNA in the rat brain.
Topics: Animals; Antidepressive Agents, Tricyclic; Blotting, Northern; Brain; Clomipramine; Desipramine; Frontal Lobe; Hippocampus; Imipramine; Male; Neuropeptide Y; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1993 |
Effect of antidepressants on striatal and accumbens extracellular dopamine levels.
Topics: Animals; Antidepressive Agents; Clomipramine; Corpus Striatum; Dopamine; Fluoxetine; Imipramine; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Time Factors | 1995 |
Desensitization of the D1 dopamine receptors in rats reproduces a model of escape deficit reverted by imipramine, fluoxetine and clomipramine.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Clomipramine; Depression; Disease Models, Animal; Escape Reaction; Fluoxetine; Imipramine; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Time Factors | 1995 |
Effect of p-chlorophenylalanine and alpha-methyltyrosine on the antinociceptive effect of antidepressant drugs.
Topics: Acetates; Acetic Acid; alpha-Methyltyrosine; Analgesia; Animals; Antidepressive Agents; Clomipramine; Drug Interactions; Fenclonine; Imipramine; Injections, Intraventricular; Maprotiline; Methyltyrosines; Mice; Norepinephrine; Random Allocation; Serotonin; Serotonin Agents; Zimeldine | 1995 |
Interaction of opioids with antidepressant-induced antinociception.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Clomipramine; Drug Combinations; Female; Imipramine; Male; Maprotiline; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pain Measurement; Random Allocation; Selective Serotonin Reuptake Inhibitors; Zimeldine | 1995 |
Characteristics of the inhibitory effect of tricyclic antidepressants on histamine release from rat peritoneal mast cells.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Binding Sites; Buffers; Calcium; Clomipramine; Desipramine; Histamine Release; Imipramine; Mast Cells; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Rats; Structure-Activity Relationship | 1996 |
Spectroscopic analysis of charge transfer complex formation and peroxidase inhibition with tricyclic antidepressant drugs: potential anti-thyroid action.
Topics: Antidepressive Agents, Tricyclic; Antithyroid Agents; Clomipramine; Desipramine; Horseradish Peroxidase; Imipramine; Iodine; Kinetics; Methimazole; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1996 |
Adaptative changes of the serotonergic system after antidepressant treatments.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Clomipramine; Clorgyline; Fluvoxamine; Frontal Lobe; Hydroxyindoleacetic Acid; Imipramine; Microdialysis; Monoamine Oxidase Inhibitors; Piperidines; Pyrimidines; Raphe Nuclei; Rats; Serotonin; Stereotaxic Techniques; Tranylcypromine; Tryptophan | 1996 |
Reduction of substance P after chronic antidepressants treatment in the striatum, substantia nigra and amygdala of the rat.
Topics: Amoxapine; Amygdala; Animals; Antidepressive Agents; Clomipramine; Corpus Striatum; Desipramine; Imipramine; Male; Mianserin; Radioimmunoassay; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Substance P; Substantia Nigra; Time Factors | 1996 |
Dysregulation of bcl-2, c-myc, and Fas expression during tricyclic antidepressant-induced apoptosis in human peripheral lymphocytes.
Topics: Antidepressive Agents, Tricyclic; Apoptosis; Cell Membrane; Citalopram; Clomipramine; fas Receptor; Gene Expression Regulation; Humans; Imipramine; Lymphocytes; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc | 1996 |
Detection of tricyclic antidepressants in whole blood by headspace solid-phase microextraction and capillary gas chromatography.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Humans; Imipramine; Male; Rats; Rats, Wistar; Sodium Hydroxide; Trimipramine; Water | 1997 |
Tricyclic antidepressant-induced lipidosis in human peripheral monocytes in vitro, as well as in a monocyte-derived cell line, as monitored by spectrofluorimetry and flow cytometry after staining with Nile red.
Topics: Antidepressive Agents, Tricyclic; Cell Line; Citalopram; Clomipramine; Flow Cytometry; Fluorescent Dyes; Humans; Imipramine; Lipidoses; Lipopolysaccharide Receptors; Microscopy, Electron; Microscopy, Fluorescence; Monocytes; Oxazines; Spectrometry, Fluorescence | 1997 |
Density of guanine nucleotide-binding proteins in platelets of patients with major depression: increased abundance of the G alpha i2 subunit and down-regulation by antidepressant drug treatment.
Topics: Adult; Antidepressive Agents; Blood Platelets; Citalopram; Clomipramine; Depressive Disorder; Dose-Response Relationship, Drug; Down-Regulation; Female; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Humans; Imipramine; Male; Middle Aged; Personality Inventory; Receptors, Adrenergic, alpha-2; Signal Transduction | 1997 |
Sensitive and rapid method for the simultaneous quantification of five antidepressants with their respective metabolites in plasma using high-performance liquid chromatography with diode-array detection.
Topics: Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Fluoxetine; Humans; Imipramine; Maprotiline; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 1997 |
The effects of selected antidepressant drugs on timing behaviour in rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Conditioning, Operant; Imipramine; Male; Rats; Zimeldine | 1998 |
Distinct effects of imipramine on 5-hydroxytryptamine uptake mediated by the recombinant rat serotonin transporter SERT1.
Topics: Allosteric Site; Animals; Antidepressive Agents, Tricyclic; Biological Transport; Carrier Proteins; Cell Line; Citalopram; Clomipramine; Desipramine; Humans; Imipramine; Kidney; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Recombinant Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sodium | 1998 |
Quantitative determination of tricyclic antidepressants and their metabolites in plasma by solid-phase extraction (Bond-Elut TCA) and separation by capillary gas chromatography with nitrogen-phosphorous detection.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Desipramine; Drug Monitoring; Humans; Imipramine; Linear Models; Nortriptyline; Promazine; Sensitivity and Specificity | 1998 |
Lung as reservoir for antidepressants in pharmacokinetic drug interactions.
Topics: Adult; Antidepressive Agents, Tricyclic; Brain; Carbon Radioisotopes; Clomipramine; Drug Interactions; Humans; Imipramine; Lung; Male; Reference Values; Selective Serotonin Reuptake Inhibitors; Tomography, Emission-Computed | 1998 |
In vivo evaluation of serotonergic agents and alpha-adrenergic blockers on premature ejaculation by inhibiting the seminal vesicle pressure response to electrical nerve stimulation.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Clomipramine; Dose-Response Relationship, Drug; Ejaculation; Electric Stimulation; Fluoxetine; Imipramine; Male; Prazosin; Pressure; Rats; Rats, Wistar; Seminal Vesicles; Serotonin; Serotonin Agents; Sexual Dysfunction, Physiological; Splanchnic Nerves; Sympatholytics | 1998 |
Guinea pig 5-HT transporter: cloning, expression, distribution, and function in intestinal sensory reception.
Topics: Amino Acid Sequence; Animals; Base Sequence; Biological Transport; Brain Stem; Carrier Proteins; Clomipramine; Cloning, Molecular; Desipramine; DNA, Complementary; Fluoxetine; Guinea Pigs; HeLa Cells; Humans; Imipramine; Intestinal Mucosa; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Nerve Tissue Proteins; Neurons; Peristalsis; Polymerase Chain Reaction; Rats; Recombinant Proteins; RNA, Messenger; Serotonin; Serotonin Plasma Membrane Transport Proteins; Transcription, Genetic; Zimeldine | 1998 |
Clomipramine and imipramine suppress clinical signs and T and B cell response to myelin proteins in experimental autoimmune neuritis in Lewis rats.
Topics: Adrenergic Uptake Inhibitors; Animals; B-Lymphocytes; Cattle; Clomipramine; Imipramine; Immunoglobulin G; Interferon-gamma; Lymphocyte Activation; Male; Myelin Proteins; Neuritis, Autoimmune, Experimental; Rats; Rats, Inbred Lew; Selective Serotonin Reuptake Inhibitors; T-Lymphocytes; Th1 Cells | 1998 |
A study of the interactions of tricyclic antidepressants with alpha 1-adrenoceptor subtypes in rat aorta and caudal arteries.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Aorta, Thoracic; Arteries; Clomipramine; Dose-Response Relationship, Drug; Drug Interactions; Imipramine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1998 |
The effect of chronic administration of antidepressants on the circadian pattern of corticosterone in the rat.
Topics: Animals; Antidepressive Agents; Circadian Rhythm; Clomipramine; Corticosterone; Desipramine; Hypothalamo-Hypophyseal System; Imipramine; Male; Phenelzine; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley | 1998 |
Effect of psychotropic drugs on taste responses in young and elderly persons.
Topics: Adult; Aged; Aging; Amitriptyline; Clomipramine; Desipramine; Doxepin; Female; Humans; Imipramine; Male; Psychotropic Drugs; Taste; Trifluoperazine | 1998 |
Nonaqueous capillary electrophoretic separation and thermo-optical absorbance detection of five tricyclic antidepressants and metabolism of amitriptyline by Cunninghamella elegans.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Cunninghamella; Desipramine; Electrophoresis, Capillary; Imipramine; Molecular Structure; Nortriptyline | 1998 |
On-line nonaqueous capillary electrophoresis and electrospray mass spectrometry of tricyclic antidepressants and metabolic profiling of amitriptyline by Cunninghamella elegans.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Calibration; Clomipramine; Cunninghamella; Desipramine; Electrophoresis, Capillary; Imipramine; Mass Spectrometry; Molecular Structure | 1998 |
Milnacipran: new preparation. Tricyclics remain first-line antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Clomipramine; Cyclopropanes; Drug Evaluation; Europe; Fluoxetine; Fluvoxamine; Humans; Imipramine; Meta-Analysis as Topic; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; United States | 1998 |
The antidepressants imipramine, clomipramine, and citalopram induce apoptosis in human acute myeloid leukemia HL-60 cells via caspase-3 activation.
Topics: Antidepressive Agents; Apoptosis; Caspase 3; Caspases; Citalopram; Clomipramine; DNA Fragmentation; Flow Cytometry; HL-60 Cells; Humans; Imipramine; In Situ Nick-End Labeling; Leukemia, Promyelocytic, Acute; Reactive Oxygen Species | 1999 |
Treatment of depression with associated anxiety: comparisons of tricyclic antidepressants and selective serotonin reuptake inhibitors.
Topics: Antidepressive Agents, Tricyclic; Anxiety Disorders; Clomipramine; Depressive Disorder, Major; Fluoxetine; Humans; Imipramine; Selective Serotonin Reuptake Inhibitors | 2000 |
Antidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitro.
Topics: Animals; Antidepressive Agents; Brain; Cell Division; Cells, Cultured; Cerebellum; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Imipramine; Nervous System; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Thymidine | 2001 |
Changes in the generation of reactive oxygen species and in mitochondrial membrane potential during apoptosis induced by the antidepressants imipramine, clomipramine, and citalopram and the effects on these changes by Bcl-2 and Bcl-X(L).
Topics: Antidepressive Agents; Apoptosis; bcl-X Protein; Cell Survival; Citalopram; Clomipramine; HL-60 Cells; Humans; Imipramine; Membrane Potentials; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Transfection | 1999 |
Availability of learned helplessness test as a model of depression compared to a forced swimming test in rats.
Topics: Amoxapine; Animals; Antidepressive Agents; Behavior, Animal; Clomipramine; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Fluvoxamine; Helplessness, Learned; Imipramine; Male; Mianserin; Motor Activity; Rats; Rats, Wistar; Swimming | 2001 |
Clomipramine and related structures as inhibitors of the skeletal sarcoplasmic reticulum Ca2+ pump.
Topics: Adenosine Triphosphate; Animals; Antidepressive Agents, Tricyclic; Calcium; Calcium-Transporting ATPases; Clomipramine; Desipramine; Enzyme Inhibitors; Imipramine; Magnesium; Muscle, Skeletal; Phosphorylation; Rabbits; Sarcoplasmic Reticulum; Trimipramine | 2000 |
[Tricyclic antidepressants as inhibitors of brain glutathione-S-transferase].
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Autopsy; Binding Sites; Brain; Clomipramine; Depressive Disorder; Doxepin; Glutathione Transferase; Humans; Imipramine | 2001 |
Tricyclic antidepressants prevent the differentiation of monocytes into macrophage-like cells in vitro.
Topics: Antidepressive Agents, Tricyclic; Antigens, Surface; Cell Differentiation; Citalopram; Clomipramine; Humans; Imipramine; Macrophages; Monocytes; Phagocytosis | 2002 |
Evaluation of the anti-inflammatory and anti-nociceptive effects of different antidepressants in the rat.
Topics: Amitriptyline; Analysis of Variance; Animals; Antidepressive Agents; Carrageenan; Clomipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Fluoxetine; Imipramine; Inflammation; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Sertraline; Trazodone | 2003 |
Cortical alpha-adrenoceptor downregulation by tricyclic antidepressants in the rat brain.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Brain; Cerebral Cortex; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Down-Regulation; Hippocampus; Imipramine; In Vitro Techniques; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Time Factors | 2003 |
Glutathione S-transferase pi as a target for tricyclic antidepressants in human brain.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Doxepin; Glutathione S-Transferase pi; Humans; Imipramine; Isoenzymes; Kinetics; Oxidation-Reduction | 2004 |
Narcolepsy in Saudi Arabia. Demographic and clinical perspective of an under-recognized disorder.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Aged; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Child; Clomipramine; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Narcolepsy; Polysomnography; Saudi Arabia | 2006 |
Development of an HPLC method for the monitoring of tricyclic antidepressants in biofluids.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Clomipramine; Doxepin; Drug Monitoring; Humans; Imipramine; Models, Chemical; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry; Time Factors; Urinalysis | 2007 |
Analysis of tricyclic antidepressant drugs in plasma by means of solid-phase microextraction-liquid chromatography-mass spectrometry.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Blood Chemical Analysis; Chromatography, Liquid; Clomipramine; Desipramine; Humans; Imipramine; Nortriptyline; Solid Phase Microextraction; Spectrometry, Mass, Electrospray Ionization | 2007 |
Photophysics and photochemistry of imipramine, desimipramine, and clomipramine in several solvents: a fluorescence, 266 nm laser flash, and theoretical study.
Topics: Clomipramine; Imipramine; Ions; Models, Chemical; Molecular Structure; Photochemistry; Solvents; Spectrometry, Fluorescence; Thermodynamics; Time Factors | 2008 |
Inhibition of glial inflammatory activation and neurotoxicity by tricyclic antidepressants.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antidepressive Agents, Tricyclic; Brain; Cell Survival; Cells, Cultured; Clomipramine; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; I-kappa B Proteins; Imipramine; Mice; Neuroglia; NF-kappaB-Inducing Kinase; Nitrites; p38 Mitogen-Activated Protein Kinases; Polysaccharides; Protein Serine-Threonine Kinases; Time Factors | 2008 |
Evaluating the role of the serotoninergic system in the control of human seminal vesicle smooth muscle-an in vitro approach.
Topics: Adrenergic alpha-Agonists; Aged; Clomipramine; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Ejaculation; Fluoxetine; Humans; Imipramine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Seminal Vesicles; Serotonin; Sexual Dysfunction, Physiological; Vas Deferens | 2009 |
Natural history, symptoms and treatment of the narcoleptic syndrome.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Cataplexy; Central Nervous System Stimulants; Clomipramine; Comorbidity; Drug Interactions; Female; Hallucinations; Humans; Imipramine; Male; Middle Aged; Narcolepsy; Sleep Paralysis; Young Adult | 1975 |
Role of human UGT2B10 in N-glucuronidation of tricyclic antidepressants, amitriptyline, imipramine, clomipramine, and trimipramine.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biocatalysis; Clomipramine; Enzyme Inhibitors; Glucuronic Acid; Glucuronides; Glucuronosyltransferase; Humans; Imipramine; Kinetics; Microsomes, Liver; Nicotine; Recombinant Proteins; Sapogenins; Trimipramine | 2010 |
Effects of pharmaceutical excipients on cloud points of amphiphilic drugs.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Bile Acids and Salts; Clomipramine; Cyclodextrins; Excipients; Fatty Acids; Imipramine; Phase Transition; Salts; Surface-Active Agents; Temperature | 2011 |
Antidepressant-like effects of an alkaloid extract of the aerial parts of Annona cherimolia in mice.
Topics: Alkaloids; Animals; Annona; Antidepressive Agents; Behavior, Animal; Brain; Clomipramine; Dopamine; Fluoxetine; Herb-Drug Interactions; Homovanillic Acid; Hydroxyindoleacetic Acid; Imipramine; Male; Medicine, Traditional; Mexico; Mice; Plant Components, Aerial; Plant Extracts; Serotonin; Swimming | 2012 |
The responsiveness of TrkB to BDNF and antidepressant drugs is differentially regulated during mouse development.
Topics: Age Factors; Animals; Antidepressive Agents; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Cell-Free System; Clomipramine; Cyclic AMP; Female; Gene Expression Regulation, Developmental; Imipramine; Male; Mice; Mice, Inbred C57BL; Models, Biological; Phosphorylation; Receptor, trkB; Signal Transduction; Time Factors | 2012 |
Electromembrane extraction combined with gas chromatography for quantification of tricyclic antidepressants in human body fluids.
Topics: Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Electrochemical Techniques; Ethers; Flame Ionization; Humans; Hydrogen-Ion Concentration; Imipramine; Limit of Detection; Membranes, Artificial; Solid Phase Extraction | 2012 |
Chronic pain treatment: the influence of tricyclic antidepressants on serotonin release and uptake in mast cells.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Biological Transport; Cells, Cultured; Chronic Pain; Clomipramine; Imipramine; Mast Cells; Rats; Rats, Wistar; Serotonin | 2013 |
Glucosylceramide and lysophosphatidylcholines as potential blood biomarkers for drug-induced hepatic phospholipidosis.
Topics: Amitriptyline; Animals; Bile Ducts; Biomarkers; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Clomipramine; Discriminant Analysis; Disease Models, Animal; Glucosylceramides; Hepatocytes; Imipramine; Least-Squares Analysis; Liver; Lysophosphatidylcholines; Lysosomal Storage Diseases; Male; Mass Spectrometry; Metabolomics; Multivariate Analysis; Predictive Value of Tests; Rats | 2014 |
A simple dried blood spot method for therapeutic drug monitoring of the tricyclic antidepressants amitriptyline, nortriptyline, imipramine, clomipramine, and their active metabolites using LC-MS/MS.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biotransformation; Calibration; Chromatography, Liquid; Clomipramine; Depressive Disorder, Major; Dried Blood Spot Testing; Drug Monitoring; Hematocrit; Humans; Imipramine; Limit of Detection; Nortriptyline; Reproducibility of Results; Tandem Mass Spectrometry | 2015 |
Combination of electromembrane extraction and electro-assisted liquid-liquid microextraction: A tandem sample preparation method.
Topics: Antidepressive Agents; Chemistry Techniques, Analytical; Chromatography, Gas; Clomipramine; Electrochemical Techniques; Humans; Hydrogen-Ion Concentration; Imipramine; Limit of Detection; Liquid Phase Microextraction; Membranes, Artificial; Solvents; Wastewater | 2018 |
A biomimetic hybrid material consisting of CaCO
Topics: Adsorption; Animals; Antidepressive Agents; Benzene Derivatives; Biomimetic Materials; Calcium Carbonate; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Clomipramine; Imipramine; Maleic Anhydrides; Microspheres; Polymers; Porosity; Proof of Concept Study; Swine | 2019 |