imipramine has been researched along with carbamazepine in 95 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 27 (28.42) | 18.7374 |
1990's | 12 (12.63) | 18.2507 |
2000's | 26 (27.37) | 29.6817 |
2010's | 28 (29.47) | 24.3611 |
2020's | 2 (2.11) | 2.80 |
Authors | Studies |
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Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
Blake, JF; Curatolo, WJ; Lombardo, F | 1 |
Strassburg, CP; Tukey, RH | 1 |
Topliss, JG; Yoshida, F | 1 |
Faller, B; Wohnsland, F | 1 |
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA | 1 |
Elshorst, B; Fiebig, K; Griesinger, C; Grimme, S; Jacobs, DM; Vogtherr, M; Zahn, R | 1 |
Faassen, F; Spanings, H; Vogel, G; Vromans, H | 1 |
Chang, TK; Ensom, MH; Kiang, TK | 1 |
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL | 1 |
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Bleich, S; Kornhuber, J; Rupprecht, R; Terfloth, L; Wiltfang, J | 1 |
Ahman, M; Holmén, AG; Wan, H | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Erdmann, F; Fischer, G; Harris, R; Hopkins, S; Huang, Z; Murray, MG; Ribeill, Y; Scorneaux, B; Smitley, C; Wring, S | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Glen, RC; Lowe, R; Mitchell, JB | 1 |
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ | 1 |
Sen, S; Sinha, N | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Artursson, P; Mateus, A; Matsson, P | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E | 1 |
Acevedo, O; Dasararaju, G; Devadasan, V; Halakova, D; Jayaprakash, V; Kovacikova, L; Mohd Siddique, MU; Mondal, SK; Prnova, MS; Shilkar, D; Stefek, M; Thakur, A; Yasmin, S | 1 |
Groh, C; Rosenmayr, FW | 1 |
Brune, GG; Reimann, I | 1 |
Fletcher, HP; Schnell, RC; Wannarka, GL | 1 |
Danielson, MG; Fowler, GW; Julien, RM | 1 |
Gastmeier, K; Hass, M; Kuteifan, K; Schott, H | 1 |
Lustman, LI; Maccario, M | 1 |
Daniel, W; Netter, KJ | 2 |
Brown, CS; Cold, JA; Froemming, JH; Jabbour, JT; Self, TH; Wells, BG | 1 |
Lothman, EW; Stringer, JL | 1 |
Akamatsu, S; Kamata, N; Kawada, J; Kurata, M; Kuwae, T; Minakuchi, K; Nishida, M; Takasugi, M; Teraoka, K | 1 |
Martinez, C; Montini, C; Oliva, J; Ramirez, H | 1 |
Schramm, T; Töppel, A; Ziebarth, D | 1 |
Baudry, M; Jones, RS; Olpe, HR | 1 |
Ballenger, JC; Gold, PW; Post, RM; Rubinow, DR | 1 |
Andreeva, NI; Golovina, SM; Mashkovskiĭ, MD | 1 |
Barros, HM; Leite, JR | 1 |
Bosch, X; Esmatjes, E; Goday, A; Gomis, R; Nubiola, A; Vendrell, J; Vilardell, E | 1 |
Fischer, W; Heydenreich, F; Rabending, G; Streubel, FR | 1 |
Dailey, JW; Jobe, PC | 1 |
Heimann, H | 1 |
Lempp, R | 1 |
Frigerio, A; Morselli, PL | 1 |
Gayford, JJ; Redpath, TH | 1 |
Trautmann, A | 1 |
Suwa, K; Toru, M | 1 |
Ciccone, JR; Kanter, GL; Yerevanian, BI | 1 |
Barros, HM; Corso, CO; Pinto-Netto, LM; Tannhauser, M; Tannhauser, SL | 1 |
O'Donnell, DJ; Reiss, AL | 1 |
Okuma, T | 1 |
Campbell, M; Cueva, JE | 1 |
Baldessarini, RJ; Castillo, J; Kando, JC; Tohen, M; Zarate, C | 1 |
Akpan, NA; Imananagha, KK; Imananagha, LN | 1 |
Daniel, WA; Wójcikowski, J | 2 |
Dehpour, AR; Farahani, M; Farsam, H; Sadeghipour-Roudsari, HR; Shokrgozar, AA | 1 |
D'Aquila, PS; Peana, AT; Serra, G; Tanda, O | 1 |
Szymura-Oleksiak, J; Wasieczko, A; Wyska, E | 1 |
Bowden, CL; Evans, DL; Gergel, IP; Gyulai, L; Nemeroff, CB; Oakes, R; Pitts, CD; Sachs, GS | 1 |
Kuo, CC; Yang, YC | 1 |
Girimaji, SC; Jairam, R; Seshadri, SP; Srinath, S | 1 |
Cantú, MD; Carrilho, E; Lacerda, CA; Lanças, FM; Queiroz, ME; Toso, DR | 1 |
Aoki, M; Chiba, H; Harada, Y; Matsumiya, T; Nohara, J; Takeda, H; Tsuji, M | 1 |
Akiyama, K; Araki, H; Gomita, Y; Kawasaki, H; Kitagawa, K; Kitamura, Y; Sendo, T; Shibata, K; Suemaru, K | 1 |
Fitch, WL; Wen, B | 1 |
Prabhu, AA; Rajendiran, N; Venkatesh, G | 1 |
Huang, CS; Kuo, CC; Yang, YC | 1 |
Hage, DS; Ohnmacht, CM; Papastavros, E; Schiel, JE; Smith, QR; Tong, Z | 1 |
Holsboer, F; Perisic, T; Rein, T; Yu, S; Zimmermann, N; Zschocke, J | 1 |
Gold, PW; Goldstein, SA; Kling, MA; Licinio, J; Michelson, D; Mouro, CM; Pavlatou, MG; Wong, ML | 1 |
Buggy, DJ; Butler, M; Gallagher, HC; Gallagher, RM; Henman, MC | 1 |
Harada, S; Matsuura, W; Tokuyama, S | 1 |
Azab, AN; Nassar, A; Sharon-Granit, Y | 1 |
Borek-Dohalska, L; Fojtikova, V; Martinkova, M; Mináriková, M; Sedláček, J; Šikut, M; Stiborová, M; Vyskočilová, E | 1 |
Bach, FW; Demant, D; Finnerup, NB; Holbech, J; Jensen, TS; Sindrup, SH | 1 |
Gilmore, IS; Hanley, L; Pieterse, CL; Rungger, I; Wickramasinghe, RC | 1 |
6 review(s) available for imipramine and carbamazepine
Article | Year |
---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The side-effects of carbamazepine.
Topics: Amitriptyline; Anemia, Aplastic; Carbamazepine; Dibenzazepines; Gastrointestinal Diseases; Humans; Imipramine; Jaundice; Lupus Erythematosus, Discoid; Nausea; Nervous System Diseases; Skin Manifestations; Trigeminal Neuralgia; Vertigo | 1969 |
Psychopharmacology in child and adolescent psychiatry: a review of the past seven years. Part II.
Topics: Adolescent; Alprazolam; Anticonvulsants; Antipsychotic Agents; Anxiety, Separation; Bipolar Disorder; Carbamazepine; Child; Child Behavior Disorders; Child, Preschool; Clonidine; Clozapine; Depressive Disorder; Dose-Response Relationship, Drug; Feeding and Eating Disorders; Fluoxetine; Humans; Imipramine; Lithium; Mutism; Obsessive-Compulsive Disorder; Phenobarbital; Phenytoin; Phobic Disorders; Schizophrenia; Sleep Wake Disorders; Tranquilizing Agents | 1995 |
Venlafaxine for neuropathic pain in adults.
Topics: Adult; Analgesics, Non-Narcotic; Antidepressive Agents, Second-Generation; Carbamazepine; Humans; Imipramine; Middle Aged; Neuralgia; Off-Label Use; Patient Dropouts; Randomized Controlled Trials as Topic; Venlafaxine Hydrochloride | 2015 |
6 trial(s) available for imipramine and carbamazepine
Article | Year |
---|---|
Possible influence of carbamazepine on plasma imipramine concentrations in children with attention deficit hyperactivity disorder.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Carbamazepine; Child; Child, Preschool; Desipramine; Drug Interactions; Drug Therapy, Combination; Female; Humans; Imipramine; Male; Retrospective Studies | 1990 |
[Quantitative EEG analysis of a single dose of psychotropic drugs in healthy probands].
Topics: Adult; Arousal; Brain; Carbamazepine; Clomipramine; Desipramine; Diazepam; Electroencephalography; Evoked Potentials; Female; Haloperidol; Humans; Imipramine; Male; Psychotropic Drugs | 1986 |
Pharmacokinetic interaction between imipramine and carbamazepine in patients with major depression.
Topics: Antidepressive Agents, Tricyclic; Antimanic Agents; Biotransformation; Carbamazepine; Depressive Disorder; Drug Interactions; Female; Humans; Imipramine; Male; Middle Aged; Protein Binding; Ultrafiltration | 2001 |
Double-blind, placebo-controlled comparison of imipramine and paroxetine in the treatment of bipolar depression.
Topics: Adult; Aged; Ambulatory Care; Anticonvulsants; Antidepressive Agents, Tricyclic; Bipolar Disorder; Carbamazepine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Imipramine; Lithium; Male; Middle Aged; Paroxetine; Placebos; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Valproic Acid | 2001 |
A prospective 4-5 year follow-up of juvenile onset bipolar disorder.
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Chlorpromazine; Diagnostic and Statistical Manual of Mental Disorders; Drug Administration Schedule; Female; Follow-Up Studies; Haloperidol; Humans; Imipramine; Lithium Carbonate; Male; Phenotype; Prospective Studies; Recovery of Function; Risperidone; Secondary Prevention; Severity of Illness Index; Valproic Acid | 2004 |
Impact of etiology and duration of pain on pharmacological treatment effects in painful polyneuropathy.
Topics: Adult; Aged; Anticonvulsants; Antidepressive Agents; Carbamazepine; Diabetic Neuropathies; Female; Humans; Imipramine; Male; Middle Aged; Neuralgia; Oxcarbazepine; Polyneuropathies; Pregabalin; Retrospective Studies; Time Factors; Venlafaxine Hydrochloride | 2017 |
83 other study(ies) available for imipramine and carbamazepine
Article | Year |
---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Computation of brain-blood partitioning of organic solutes via free energy calculations.
Topics: Animals; Blood-Brain Barrier; Brain; Cattle; Cells, Cultured; Endothelium, Vascular; Membrane Lipids; Microcirculation; Molecular Conformation; Molecular Structure; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Software; Solubility; Thermodynamics | 1996 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations | 2002 |
Antimalarial drug quinacrine binds to C-terminal helix of cellular prion protein.
Topics: Antimalarials; Binding Sites; Chloroquine; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Peptide Fragments; Phenothiazines; Prions; Protein Structure, Secondary; Quinacrine; Recombinant Proteins; Structure-Activity Relationship | 2003 |
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport | 2003 |
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride | 2005 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Molecular properties of psychopharmacological drugs determining non-competitive inhibition of 5-HT3A receptors.
Topics: Binding Sites; Computer Simulation; Databases, Factual; Models, Chemical; Models, Molecular; Molecular Structure; Molecular Weight; Psychotropic Drugs; Serotonin 5-HT3 Receptor Antagonists; Structure-Activity Relationship | 2009 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
SCY-635, a novel nonimmunosuppressive analog of cyclosporine that exhibits potent inhibition of hepatitis C virus RNA replication in vitro.
Topics: Animals; Antiviral Agents; Cell Line; Cells, Cultured; Cyclophilin A; Cyclosporins; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Haplorhini; Hepacivirus; Hepatitis C; Hepatocytes; Humans; Immunosuppressive Agents; Interleukin-2; Jurkat Cells; Leukocytes, Mononuclear; Mice; Molecular Structure; Rats; RNA, Viral; Virus Replication | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results | 2011 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship | 2017 |
Non-carboxylic acid inhibitors of aldose reductase based on N-substituted thiazolidinedione derivatives.
Topics: Aldehyde Reductase; Animals; Caco-2 Cells; Catalytic Domain; Dogs; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Madin Darby Canine Kidney Cells; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Rats, Wistar; Structure-Activity Relationship; Thiazolidinediones | 2021 |
[Borderline between antiepileptic and psychopharmacological drugs (author's transl)].
Topics: Amitriptyline; Anticonvulsants; Antipsychotic Agents; Barbiturates; Carbamazepine; Child; Child Behavior Disorders; Drug Therapy, Combination; Ethosuximide; Humans; Imipramine; Nialamide; Phenothiazines; Primidone; Thioxanthenes; Tranquilizing Agents | 1975 |
[Short-term and long-term effects of psychotropic drugs in the treatment of trigeminal neuralgia (author's transl)].
Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Benperidol; Carbamazepine; Drug Therapy, Combination; Humans; Imipramine; Trigeminal Neuralgia | 1979 |
Variations of chlorpromazine-related isosteres on the glycemic response in mice.
Topics: Adrenalectomy; Animals; Blood Glucose; Carbamazepine; Chlorpromazine; Clomipramine; Cyproheptadine; Hyperglycemia; Imipramine; Insulin; Islets of Langerhans; Male; Mice; Promazine | 1979 |
The effects of antiepileptic drugs on estrogen-induced electrographic spike-wave discharge.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Clonazepam; Clorazepate Dipotassium; Diazepam; Electroencephalography; Estrogens; Ethosuximide; Female; Imipramine; Lidocaine; Male; Motor Cortex; Phenytoin; Stereotaxic Techniques; Trimethadione | 1975 |
[Pain therapy for urologic cancer patients at the Potsdam district hospital--initial results].
Topics: Aged; Amitriptyline; Analgesics; Analgesics, Opioid; Aspirin; Carbamazepine; Codeine; Dipyrone; Drug Therapy, Combination; Haloperidol; Humans; Imipramine; Indomethacin; Meperidine; Morphine; Pain; Pain Measurement; Prospective Studies; Urologic Neoplasms | 1990 |
Paroxysmal nocturnal dystonia presenting as excessive daytime somnolence.
Topics: Adult; Carbamazepine; Diagnosis, Differential; Dystonia; Electroencephalography; Evaluation Studies as Topic; Female; Humans; Imipramine; Male; Middle Aged; Phenobarbital; Sleep Stages; Sleep Wake Disorders; Trifluoperazine; Valproic Acid | 1990 |
Alteration of cytochrome P-450 by prolonged administration of imipramine and/or lithium to rats.
Topics: Animals; Carbamazepine; Cytochrome P-450 Enzyme System; Desipramine; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Hexobarbital; Imipramine; Isoenzymes; Lithium; Liver; Male; Metyrapone; Rats; Rats, Inbred Strains | 1990 |
Use of maximal dentate activation to study the effect of drugs on kindling and kindled responses.
Topics: Animals; Carbamazepine; Desipramine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Hippocampus; Imipramine; Kindling, Neurologic; Male; Molecular Structure; Rats; Rats, Inbred Strains | 1990 |
Effect of lithium carbonate administration singly or in combination with some psychotropic drugs on the radioiodide uptake by mouse thyroid.
Topics: Animals; Carbamazepine; Drug Interactions; Female; Haloperidol; Imipramine; Iodides; Iodine Radioisotopes; Lithium; Lithium Carbonate; Male; Mice; Mice, Inbred Strains; Psychotropic Drugs; Sex Factors; Thyroid Gland; Thyroxine; Triiodothyronine | 1989 |
[Pharmacotherapy of trigeminal neuralgia].
Topics: Amphetamines; Baclofen; Carbamazepine; Female; Humans; Imipramine; Male; Phenytoin; Trigeminal Neuralgia | 1989 |
[Drugs from the classes of tricyclic antidepressives and antiepileptics, nitrosatable under simulated human gastric conditions].
Topics: Carbamazepine; Dibenzazepines; Gastric Mucosa; Humans; Imipramine; In Vitro Techniques; Nitrites; Nitrosamines; Nitrosation; Nitroso Compounds; Trimipramine | 1989 |
Electrophysiological and neurochemical investigations on the action of carbamazepine on the rat hippocampus.
Topics: Anesthetics, Local; Animals; Caffeine; Carbamazepine; Depression, Chemical; Glutamates; Glutamic Acid; Hippocampus; Imipramine; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Sodium; Synaptic Transmission; Tritium | 1985 |
CSF somatostatin in affective illness and normal volunteers.
Topics: Bipolar Disorder; Carbamazepine; Depressive Disorder; Desipramine; Humans; Imipramine; Lithium; Lithium Carbonate; Somatostatin; Zimeldine | 1985 |
[Interaction of antidepressants and anticonvulsants in anticonvulsive and anti-reserpine tests].
Topics: Animals; Anticonvulsants; Antidepressive Agents; Carbamazepine; Carbazoles; Convulsants; Drug Interactions; Female; Imipramine; Male; Mice; Reserpine; Semicarbazides; Valproic Acid | 1986 |
The effects of carbamazepine on two animal models of depression.
Topics: Animals; Carbamazepine; Depressive Disorder; Disease Models, Animal; Haloperidol; Imipramine; Male; Methamphetamine; Motivation; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1987 |
Metabolic interaction between imipramine and carbamazepine in vivo and in vitro in rats.
Topics: Animals; Carbamazepine; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Drug Interactions; Imipramine; In Vitro Techniques; Male; Microsomes, Liver; Rats; Rats, Inbred Strains | 1988 |
Erythromelalgia associated with acute diabetic neuropathy: an unusual condition.
Topics: Acute Disease; Adult; Carbamazepine; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Erythromelalgia; Humans; Imipramine; Inositol; Male; Pain | 1988 |
Anticonvulsant drugs and the genetically epilepsy-prone rat.
Topics: Acoustic Stimulation; Amitriptyline; Animals; Anticonvulsants; Carbamazepine; Desipramine; Disease Models, Animal; Epilepsy; Ethosuximide; Imipramine; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1985 |
[Investigation of psychotropic substances in man].
Topics: Behavior; Carbamazepine; Dose-Response Relationship, Drug; Drug Evaluation; Electroencephalography; Humans; Hypnotics and Sedatives; Imipramine; Lysergic Acid Diethylamide; MMPI; Models, Psychological; Personality; Placebos; Psilocybin; Psychotropic Drugs | 1974 |
[German pharmacopoeia, 7th edition. IX. Delivery].
Topics: Alcohols; Amino Alcohols; Barbiturates; Blood Group Antigens; Carbamazepine; Cyclopentanes; Dexamethasone; Digitoxin; Germany, East; Glyburide; Imipramine; Immune Sera; Indocyanine Green; Infusions, Parenteral; Mephentermine; Mydriatics; Nandrolone; Parasympatholytics; Pharmacopoeias as Topic; Phenylacetates; Piperidines; Propoxycaine; Propylamines; Smallpox Vaccine; Structure-Activity Relationship; Thyroxine; Triiodothyronine | 1973 |
[Therapy of nocturnal enuresis in infancy].
Topics: Antidepressive Agents; Barbiturates; Carbamazepine; Child; Child, Preschool; Enuresis; Humans; Hydantoins; Imipramine; Psychotherapy | 1973 |
Gas chromatographic-mass spectrometric studies of tricyclic compounds used in psychiatry.
Topics: Carbamazepine; Chromatography, Gas; Imipramine; Mass Spectrometry; Tranquilizing Agents | 1973 |
[Dialysis of drugs and poisons. 2].
Topics: Acetaminophen; Aminopyrine; Amitriptyline; Aspirin; Carbamazepine; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Heroin; Humans; Imipramine; Lithium; Pargyline; Pentazocine; Phenacetin; Phenelzine; Phenytoin; Poisoning; Primidone; Promazine; Renal Dialysis; Salicylates; Tranylcypromine; Trifluoperazine | 1972 |
A case of periodic somnolence whose sleep was induced by glucose.
Topics: Adolescent; Adult; Carbamazepine; Depression; Electroencephalography; Food Preferences; Glucose; Humans; Hunger; Imipramine; Male; Mental Disorders; Paresthesia; Pedigree; Periodicity; Phenobarbital; Potassium; Psychological Tests; Sleep Wake Disorders | 1969 |
Case report of a possible interaction between neuroleptics and carbamazepine.
Topics: Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Delirium; Drug Interactions; Female; Haloperidol; Humans; Imipramine; Middle Aged; Thioridazine | 1984 |
Effects of carbamazepine or imipramine alone or in association with amphetamine on the fighting time of REM sleep-deprived rats.
Topics: Aggression; Animals; Carbamazepine; Dextroamphetamine; Humans; Imipramine; Male; Rats; Rats, Inbred Strains; Sleep Deprivation | 1984 |
Carbamazepine-induced mania in two children: case report.
Topics: Age Factors; Bipolar Disorder; Carbamazepine; Chemical Phenomena; Chemistry; Child; Depressive Disorder; Dextroamphetamine; Epilepsy, Temporal Lobe; Humans; Imipramine; Male; Risk; Structure-Activity Relationship | 1984 |
Differential sensitivity to the effects of psychotropic drugs: psychotics vs normals; Asian vs Western populations.
Topics: Bipolar Disorder; Carbamazepine; Chlorpromazine; Cross-Cultural Comparison; Dose-Response Relationship, Drug; Drug Tolerance; Electroencephalography; Humans; Imipramine; Japan; Psychotropic Drugs; Schizophrenia | 1981 |
Blood dyscrasias with carbamazepine and valproate: a pharmacoepidemiological study of 2,228 patients at risk.
Topics: Adolescent; Adult; Anemia; Carbamazepine; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; Hospitalization; Humans; Imipramine; Leukopenia; Male; Middle Aged; Pharmacoepidemiology; Prevalence; Severity of Illness Index; Thrombocytopenia; Valproic Acid | 1995 |
Thalamic pain syndrome of Dejerine-Roussy.
Topics: Adult; Carbamazepine; Cerebrovascular Disorders; Female; Hospitals, University; Humans; Imipramine; Male; Middle Aged; Nigeria; Pain; Syndrome; Thalamus | 1993 |
Contribution of lysosomal trapping to the total tissue uptake of psychotropic drugs.
Topics: 1-Naphthylamine; Amitriptyline; Ammonium Chloride; Animals; Antidepressive Agents, Tricyclic; Carbamazepine; Drug Interactions; Fluoxetine; Imipramine; Lysosomes; Male; Monensin; Phospholipids; Promazine; Psychotropic Drugs; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Sertraline; Tissue Distribution | 1997 |
Interactions between promazine and antidepressants at the level of cellular distribution.
Topics: 1-Naphthylamine; Amitriptyline; Ammonium Chloride; Animals; Antidepressive Agents; Antipsychotic Agents; Carbamazepine; Drug Interactions; Fluoxetine; Hydrogen-Ion Concentration; Imipramine; Lysosomes; Male; Promazine; Rats; Rats, Wistar; Sertraline | 1997 |
Decrease in erythrocyte:plasma lithium ratio by concurrent administration of psychotropic drugs and lithium in mice.
Topics: Animals; Antipsychotic Agents; Carbamazepine; Chlorpromazine; Drug Therapy, Combination; Erythrocytes; Haloperidol; Imipramine; Lithium; Male; Mice; Prospective Studies | 1998 |
Carbamazepine prevents imipramine-induced behavioural sensitization to the dopamine D(2)-like receptor agonist quinpirole.
Topics: Analysis of Variance; Animals; Behavior, Animal; Carbamazepine; Dopamine Agonists; Imipramine; Male; Motor Activity; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2 | 2001 |
Inhibition of Na(+) current by imipramine and related compounds: different binding kinetics as an inactivation stabilizer and as an open channel blocker.
Topics: Adrenergic Uptake Inhibitors; Amino Acid Motifs; Animals; Binding Sites; Carbamazepine; Diphenhydramine; Dose-Response Relationship, Drug; Imipramine; Kinetics; Membrane Potentials; Mutation; Protein Conformation; Rats; Rats, Long-Evans; Sodium Channel Blockers; Sodium Channels | 2002 |
Optimization of solid-phase microextraction procedures for the determination of tricyclic antidepressants and anticonvulsants in plasma samples by liquid chromatography.
Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Chromatography, Liquid; Desipramine; Epoxy Compounds; Humans; Hydrogen-Ion Concentration; Imipramine; Lamotrigine; Nortriptyline; Phenobarbital; Phenylethylmalonamide; Polyurethanes; Primidone; Reproducibility of Results; Sensitivity and Specificity; Silanes; Time Factors; Triazines | 2006 |
Antidepressants enhance the antinociceptive effects of carbamazepine in the acetic acid-induced writhing test in mice.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Carbamazepine; Cyclopropanes; Fluvoxamine; Imipramine; Male; Mice; Mice, Inbred ICR; Milnacipran; Pain; Pain Measurement | 2006 |
Chronic coadministration of carbamazepine together with imipramine produces antidepressant-like effects in an ACTH-induced animal model of treatment-resistant depression: involvement of 5-HT(2A) receptors?
Topics: Adrenocorticotropic Hormone; Amphetamines; Animals; Antidepressive Agents; Carbamazepine; Depression; Disease Models, Animal; Drug Therapy, Combination; Imipramine; Male; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A | 2008 |
Screening and characterization of reactive metabolites using glutathione ethyl ester in combination with Q-trap mass spectrometry.
Topics: Acetaminophen; Amodiaquine; Carbamazepine; Glutathione; Humans; Imipramine; Mass Spectrometry; Metabolomics; Microsomes, Liver; Phenols; Reproducibility of Results; Sensitivity and Specificity; Ticlopidine | 2009 |
Unusual spectral shifts of imipramine and carbamazepine drugs.
Topics: beta-Cyclodextrins; Carbamazepine; Hydrogen Bonding; Imipramine; Models, Molecular; Molecular Structure; Reference Standards; Solvents; Spectrometry, Fluorescence; Viscosity | 2010 |
Lidocaine, carbamazepine, and imipramine have partially overlapping binding sites and additive inhibitory effect on neuronal Na+ channels.
Topics: Anesthetics, Local; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Binding Sites; Brain; Carbamazepine; Drug Synergism; Imipramine; Lidocaine; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Sodium Channels | 2010 |
Kinetic studies of drug-protein interactions by using peak profiling and high-performance affinity chromatography: examination of multi-site interactions of drugs with human serum albumin columns.
Topics: Carbamazepine; Chromatography, Affinity; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Imipramine; Immobilized Proteins; Kinetics; Protein Binding; Serum Albumin; Temperature | 2011 |
Antidepressants inhibit DNA methyltransferase 1 through reducing G9a levels.
Topics: Animals; Antidepressive Agents; Astrocytes; Carbamazepine; Cells, Cultured; Cerebral Cortex; Citalopram; Cyclohexanols; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Glycolipids; Histone-Lysine N-Methyltransferase; Imipramine; Indoles; Maleimides; Mice; Nerve Tissue Proteins; Neural Stem Cells; Neurons; Paroxetine; Protein Interaction Mapping; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Venlafaxine Hydrochloride | 2012 |
Chronic administration of anticonvulsants but not antidepressants impairs bone strength: clinical implications.
Topics: Animals; Anticonvulsants; Antidepressive Agents; Bone and Bones; Bone Density; Carbamazepine; Femur; Fluoxetine; Imipramine; Male; Rats; Rats, Sprague-Dawley; Valproic Acid; X-Ray Microtomography | 2015 |
Effects of Adjuvant Analgesics on Cerebral Ischemia-Induced Mechanical Allodynia.
Topics: Amines; Analgesics; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Brain Ischemia; Carbamazepine; Chemotherapy, Adjuvant; Cyclohexanecarboxylic Acids; Cyclopropanes; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Imipramine; Indomethacin; Male; Mexiletine; Mice; Milnacipran; Morphine; Neuralgia; Paroxetine; Selective Serotonin Reuptake Inhibitors | 2016 |
Psychotropic drugs attenuate lipopolysaccharide-induced hypothermia by altering hypothalamic levels of inflammatory mediators in rats.
Topics: Animals; Carbamazepine; Dinoprostone; Encephalitis; Haloperidol; Hypothalamus; Hypothermia; Imipramine; Inflammation Mediators; Lipopolysaccharides; Lithium; Male; Neoplasm Proteins; Nucleocytoplasmic Transport Proteins; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2016 |
The capacity and effectiveness of diosmectite and charcoal in trapping the compounds causing the most frequent intoxications in acute medicine: A comparative study.
Topics: Adsorption; Alpha-Amanitin; Amlodipine; Antidotes; Aspirin; Carbamazepine; Charcoal; Digoxin; Ibuprofen; Imipramine; Oxazepam; Phenobarbital; Poisoning; Promethazine; Silicates; Theophylline | 2017 |
An Experimental and Theoretical Study of Laser Postionization of Femtosecond-Laser-Desorbed Drug Molecules.
Topics: Carbamazepine; Ciprofloxacin; Imipramine; Ions; Kinetics; Lasers; Models, Molecular; Molecular Conformation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Verapamil | 2020 |