imipramine and benztropine

imipramine has been researched along with benztropine in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199019 (63.33)18.7374
1990's2 (6.67)18.2507
2000's4 (13.33)29.6817
2010's3 (10.00)24.3611
2020's2 (6.67)2.80

Authors

AuthorsStudies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Alonso, C; Campillo, NE; Cuesta-Geijo, MÁ; Delgado, R; Gil, C; Ginex, T; Morales-Tenorio, M; Muñoz-Fontela, C1
Chen, W; Han, S; Hu, Y; Li, H; Tong, X; Yang, L; Zuo, J1
Richelson, E1
Gardos, G1
Tuomisto, J; Tuomisto, L1
Kalman, T; Warner, GM1
Moore, KE; Wuerthele, SM1
Ghosh, PK; Hrdina, PD1
Dutchak, D; Greden, JF; Tandon, R1
Aronson, A; Sellew, AP; Siris, SG1
Cutler, J; Gingerich, S; Lang, MP; Mason, S; Owen, K; Siris, SG1
Adan, F; Aronson, A; Casey, E; Cohen, M; Mandeli, J; Siris, SG1
Siris, SG; Strahan, A1
Casey, E; Cooper, TB; Frechen, K; Mandell, J; Sellew, AP; Siris, SG1
Adan, F; Aronson, A; Cohen, M; Fasano-Dube, B; Mandeli, J; Siris, SG1
Banno, V; Jones, BD; Moreau, A1
Squires, RF1
Dandiya, PC; Kulkarni, SK1
Scheel-Krüger, J1
November, M; Reardon, GT; Rifkin, A; Siris, SG1
Kulik, AV; Wilbur, R1
Bermanzohn, PC; Mason, SE; Shuwall, MA; Siris, SG1
Kuo, CC1
Bermanzohn, P; Pollack, S; Siris, S; Stronger, R1
Avci, A; Tahiroglu, AY1

Reviews

2 review(s) available for imipramine and benztropine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Potential pharmacological strategies targeting the Niemann-Pick C1 receptor and Ebola virus glycoprotein interaction.
    European journal of medicinal chemistry, 2021, Nov-05, Volume: 223

    Topics: Antibodies; Ebolavirus; Glycoproteins; Hemorrhagic Fever, Ebola; Humans; Molecular Docking Simulation; Niemann-Pick C1 Protein; Protein Binding; Small Molecule Libraries; Virus Internalization

2021

Trials

7 trial(s) available for imipramine and benztropine

ArticleYear
Imipramine-responsive panic-like symptomatology in schizophrenia/schizoaffective disorder.
    Biological psychiatry, 1989, Feb-15, Volume: 25, Issue:4

    Topics: Adult; Benztropine; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Fear; Female; Fluphenazine; Humans; Imipramine; Panic; Psychotic Disorders; Schizophrenia; Schizophrenic Psychology

1989
Postpsychotic depression and negative symptoms: an investigation of syndromal overlap.
    The American journal of psychiatry, 1988, Volume: 145, Issue:12

    Topics: Adolescent; Adult; Aged; Benztropine; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Fluphenazine; Humans; Imipramine; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Random Allocation; Schizophrenia; Schizophrenic Psychology

1988
Antidepressants in the treatment of post-psychotic depression in schizophrenia: drug interactions and other considerations.
    Clinical chemistry, 1988, Volume: 34, Issue:5

    Topics: Adult; Affective Disorders, Psychotic; Benztropine; Clinical Trials as Topic; Drug Interactions; Fluphenazine; Humans; Imipramine; Middle Aged; Schizophrenia; Time Factors; Tropanes

1988
Targeted treatment of depression-like symptoms in schizophrenia.
    Psychopharmacology bulletin, 1987, Volume: 23, Issue:1

    Topics: Benztropine; Depression; Drug Therapy, Combination; Fluphenazine; Humans; Imipramine; Schizophrenia

1987
Comparative side effects of imipramine, benztropine, or their combination in patients receiving fluphenazine decanoate.
    The American journal of psychiatry, 1983, Volume: 140, Issue:8

    Topics: Adult; Benztropine; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Fluphenazine; Humans; Imipramine; Male; Middle Aged; Tropanes

1983
Maintenance imipramine therapy for secondary depression in schizophrenia. A controlled trial.
    Archives of general psychiatry, 1994, Volume: 51, Issue:2

    Topics: Adult; Antipsychotic Agents; Benztropine; Delayed-Action Preparations; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Fluphenazine; Humans; Imipramine; Male; Middle Aged; Placebos; Psychotic Disorders; Recurrence; Schizophrenia; Schizophrenic Psychology

1994
Adjunctive imipramine for a broader group of post-psychotic depressions in schizophrenia.
    Schizophrenia research, 2000, Sep-01, Volume: 44, Issue:3

    Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benztropine; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Female; Fluphenazine; Humans; Imipramine; Male; Muscarinic Antagonists; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Time Factors

2000

Other Studies

21 other study(ies) available for imipramine and benztropine

ArticleYear
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Discovery of potent ebola entry inhibitors with (3S,4aS,8aS)-2-(3-amino-2-hydroxypropyl) decahydroisoquinoline-3-carboxamide scaffold.
    European journal of medicinal chemistry, 2022, Oct-05, Volume: 240

    Topics: Antiviral Agents; Ebolavirus; Hemorrhagic Fever, Ebola; HIV Fusion Inhibitors; Humans; Molecular Docking Simulation; Virus Internalization

2022
Tricyclic antidepressants and histamine H1 receptors.
    Mayo Clinic proceedings, 1979, Volume: 54, Issue:10

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Atropine; Benztropine; Cells, Cultured; Clozapine; Cyproheptadine; Desipramine; Doxepin; Haloperidol; Histamine H1 Antagonists; Hydroxyzine; Imipramine; Mice; Neoplasms, Experimental; Neuroblastoma; Nortriptyline; Protriptyline; Receptors, Histamine; Receptors, Histamine H1; Receptors, Muscarinic

1979
A case of withdrawal dyskinesia.
    The American journal of psychiatry, 1979, Volume: 136, Issue:8

    Topics: Benztropine; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Humans; Imipramine; Middle Aged; Substance Withdrawal Syndrome; Thioridazine

1979
The accumulation of dopamine into striatal synaptosomes, and its inhibition: comparison of crude, partially purified and purified synaptosomal preparations.
    Medical biology, 1979, Volume: 57, Issue:4

    Topics: Amphetamine; Animals; Benztropine; Chlorpromazine; Corpus Striatum; Dopamine; Imipramine; Kinetics; Nomifensine; Rats; Receptors, Dopamine; Reserpine; Subcellular Fractions; Synaptosomes

1979
Protracted vomiting following abrupt cessation of psychotropics: a case report.
    Canadian Psychiatric Association journal, 1978, Volume: 23, Issue:3

    Topics: Adult; Benztropine; Depression; Drug Therapy, Combination; Haloperidol; Humans; Imipramine; Male; Schizophrenia; Substance Withdrawal Syndrome; Tropanes; Vomiting

1978
Studies on the mechanisms of L-dopa-induced depletion of 5-hydroxytryptamine in the mouse brain.
    Life sciences, 1977, May-15, Volume: 20, Issue:10

    Topics: Amines; Animals; Benztropine; Biological Transport; Brain; Clomipramine; Cocaine; Dihydroxyphenylalanine; Dopamine; Imipramine; Levodopa; Male; Mice; Mice, Inbred ICR; Serotonin; Tryptophan

1977
Effects of tricyclic antidepressants on the content and metabolism of dopamine in the rat striatum.
    Canadian journal of physiology and pharmacology, 1977, Volume: 55, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Benztropine; Corpus Striatum; Desipramine; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Imipramine; Male; Rats; Time Factors

1977
Cholinergic syndrome following anticholinergic withdrawal in a schizophrenic patient abusing marijuana.
    The British journal of psychiatry : the journal of mental science, 1989, Volume: 154

    Topics: Adult; Benztropine; Brain; Humans; Imipramine; Male; Marijuana Abuse; Receptors, Cholinergic; Schizophrenia, Paranoid; Substance Withdrawal Syndrome; Substance-Related Disorders; Syndrome; Thiothixene; Tropanes

1989
Adjunctive imipramine maintenance treatment in schizophrenic patients with remitted postpsychotic depression.
    The American journal of psychiatry, 1989, Volume: 146, Issue:11

    Topics: Adult; Benztropine; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Fluphenazine; Humans; Imipramine; Middle Aged; Psychotic Disorders; Tranquilizing Agents

1989
Continuation and maintenance treatment trials of adjunctive imipramine therapy in patients with postpsychotic depression.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:11

    Topics: Benztropine; Depressive Disorder; Drug Therapy, Combination; Fluphenazine; Humans; Imipramine; Psychotic Disorders; Recurrence; Schizophrenia; Substance Withdrawal Syndrome

1988
Chronic central anticholinergic toxicity in manic depressive illness mimicking dementia.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1986, Volume: 31, Issue:4

    Topics: Aged; Amitriptyline; Benztropine; Bipolar Disorder; Central Nervous System Diseases; Dementia; Diagnostic Errors; Female; Humans; Imipramine; Thioridazine; Tropanes

1986
Effects of noradrenaline pump blockers on its uptake by synaptosomes from several brain regions; additional evidence for dopamine terminals in the frontal cortex.
    The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:5

    Topics: Amitriptyline; Animals; Benztropine; Biological Transport, Active; Carbon Radioisotopes; Cerebral Cortex; Desipramine; Dibenzazepines; Dopamine; Frontal Lobe; Imipramine; Mice; Norepinephrine; Synaptosomes; Tritium

1974
A preliminary report on the action of imipramine and antiparkinsonian agents on the open field behaviour of rats.
    Japanese journal of pharmacology, 1974, Volume: 24, Issue:5

    Topics: Animals; Antiparkinson Agents; Behavior, Animal; Benztropine; Dihydroxyphenylalanine; Humans; Imipramine; Male; Rats; Stereotyped Behavior; Time Factors

1974
Behavioural and biochemical comparison of amphetamine derivatives, cocaine, benztropine and tricyclic anti-depressant drugs.
    European journal of pharmacology, 1972, Volume: 18, Issue:1

    Topics: Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Benztropine; Brain; Brain Chemistry; Cocaine; Desipramine; Dopamine; Imipramine; Iproniazid; Male; Motor Activity; Nialamide; Norepinephrine; Normetanephrine; Parasympatholytics; Rats; Rats, Inbred Strains; Stimulation, Chemical; Tropanes; Tyramine

1972
Delirium and stereotypy from anticholinergic antiparkinson drugs.
    Progress in neuro-psychopharmacology & biological psychiatry, 1982, Volume: 6, Issue:1

    Topics: Adult; Aged; Benztropine; Delirium; Diazepam; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Ethchlorvynol; Female; Haloperidol; Humans; Imipramine; Phenobarbital; Psychoses, Substance-Induced; Stereotyped Behavior; Substance-Related Disorders; Tropanes

1982
Imipramine inhibition of transient K+ current: an external open channel blocker preventing fast inactivation.
    Biophysical journal, 1998, Volume: 75, Issue:6

    Topics: Animals; Antidepressive Agents, Tricyclic; Benztropine; Binding Sites; Biophysical Phenomena; Biophysics; Diphenhydramine; Hippocampus; Hydrogen-Ion Concentration; Imipramine; In Vitro Techniques; Ion Channel Gating; Kinetics; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Protein Conformation; Rats

1998
Polypharmacy and EPS in a child; a case report.
    Psychopharmacology bulletin, 2007, Volume: 40, Issue:2

    Topics: Attention Deficit Disorder with Hyperactivity; Benztropine; Bipolar Disorder; Child; Comorbidity; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Imipramine; Injections, Intramuscular; Methylphenidate; Neurologic Examination; Ocular Motility Disorders; Psychotropic Drugs; Valproic Acid

2007