imipramine and amantadine

imipramine has been researched along with amantadine in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199015 (36.59)18.7374
1990's0 (0.00)18.2507
2000's16 (39.02)29.6817
2010's9 (21.95)24.3611
2020's1 (2.44)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Akazawa, M; Inui, K; Okuda, M; Saito, H; Urakami, Y1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Gozalbes, R; Pineda-Lucena, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Brea, JM; Companys-Alemany, J; Griñán-Ferré, C; Johnson, JW; Kurnikova, MG; Loza, MI; Pallàs, M; Patel, DS; Pérez, B; Phillips, MB; Soto, D; Sureda, FX; Turcu, AL; Vázquez, S1
Anand, M; Bhargava, KP; Gupta, GP1
Anami, K; Fukuda, T; Maruyama, Y; Morimoto, Y; Setoguchi, M; Usa, T1
Wesemann, W; Zilliken, F1
Shibasaki, H1
Shibazaki, H1
Duvoisin, RC; Yahr, MD1
Tolosa, E1
Harmon, JB; Lynes, TE; Marvel, JP; Smith, DH; Stump, JM; Vernier, VG1
Castaigne, P; Dordain, G; Laplane, D1
Birkmayer, W1
Florio, V; Longo, VG1
De Carolis, AS; Del Basso, P; Longo, VG; Ziegler, H1
Baldessarini, RJ; Vogt, M1
Hostetler, KY; Matsuzawa, Y1
Budziszewska, B; Jaworska-Feil, L; Kajta, M; Lasoń, W1
Vamvakidès, A1
Dlaboga, D; Dziedzicka-Wasylewska, M; Rogóz, Z1
Isobe, M; Iwama, T; Kawabata, M; Kubo, I; Suzuki, K; Terai, T1
Dziedzicka-Wasylewska, M; Faron-Górecka, A; Rogóz, Z; Solich, J1
Basta-Kaim, A; Budziszewska, B; Jaworska-Feil, L; Kubera, M; Lason, W; Leskiewicz, M; Maes, M; Rogóz, Z; Skuza, G; Tetich, M1
Legutko, B; Rogóz, Z; Skuza, G1
Perry, MS; Turner, AL1

Reviews

7 review(s) available for imipramine and amantadine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Parkinson's syndrome. Recent progress in the medical treatment and its pharmacological basis.
    Minnesota medicine, 1971, Volume: 54, Issue:10

    Topics: Amantadine; Atropine; Catecholamines; Dihydroxyphenylalanine; Histamine H1 Antagonists; Humans; Imipramine; Parkinson Disease; Tryptophan

1971
[Recent advances and pharmacological basis of the medical treatment of Parkinson's syndrome].
    Shinkei kenkyu no shimpo. Advances in neurological sciences, 1971, Volume: 15, Issue:4

    Topics: Amantadine; Catecholamines; Dihydroxyphenylalanine; Histamine H1 Antagonists; Humans; Imipramine; Parasympatholytics; Parkinson Disease; Tryptophan

1971
Drug therapy of parkinsonism.
    The New England journal of medicine, 1972, Jul-06, Volume: 287, Issue:1

    Topics: Amantadine; Amitriptyline; Amphetamine; Antiparkinson Agents; Dihydroxyphenylalanine; Drug Antagonism; Drug Synergism; Humans; Imipramine; Methyldopa; Monoamine Oxidase Inhibitors; Parasympatholytics; Parkinson Disease; Phenothiazines

1972
Parkinson's disease; modern treatment.
    Minnesota medicine, 1973, Volume: 56, Issue:6

    Topics: Amantadine; Amphetamine; Antidepressive Agents; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Catechol O-Methyltransferase Inhibitors; Desipramine; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Drug Combinations; Drug Incompatibility; Drug Synergism; Humans; Imipramine; Monoamine Oxidase Inhibitors; Parasympatholytics; Parkinson Disease

1973
[Therapy of Parkinsonism. II].
    La Clinica terapeutica, 1974, Nov-30, Volume: 71, Issue:4

    Topics: Amantadine; Amitriptyline; Humans; Imipramine; Levodopa; Parkinson Disease; Physical Therapy Modalities

1974
Outside the box: Medications worth considering when traditional antiepileptic drugs have failed.
    Seizure, 2017, Volume: 50

    Topics: Amantadine; Anticonvulsants; Bumetanide; Central Nervous System Stimulants; Epilepsy; Humans; Imipramine; Lidocaine; Treatment Failure; Verapamil

2017

Other Studies

34 other study(ies) available for imipramine and amantadine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 predominantly expressed in the human kidney.
    Journal of the American Society of Nephrology : JASN, 2002, Volume: 13, Issue:7

    Topics: Alternative Splicing; Amino Acid Sequence; Base Sequence; Cations; Cell Line; Cloning, Molecular; DNA, Complementary; Genetic Variation; Humans; Kidney; Molecular Sequence Data; Organic Cation Transport Proteins; Organic Cation Transporter 2; Tetraethylammonium; Tissue Distribution; Transfection

2002
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease.
    European journal of medicinal chemistry, 2022, Jun-05, Volume: 236

    Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Disease Models, Animal; Memantine; Mice; Receptors, N-Methyl-D-Aspartate

2022
Modification of electroshock fighting by drugs known to interact with dopaminergic and noradrenergic neurons in normal and brain lesioned rats.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:7

    Topics: Aggression; Amantadine; Animals; Apomorphine; Brain; Ditiocarb; Dopamine; Electroshock; Humans; Imipramine; Levodopa; Male; Neurons; Norepinephrine; Rats; Reserpine

1977
[Pharmacological studies on Y-8894. (III). Its effect on the abnormal electrocorticogram induced by destruction of the internal capsule].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 88, Issue:4

    Topics: Amantadine; Animals; Cerebral Cortex; Delta Rhythm; Electroencephalography; gamma-Aminobutyric Acid; Imipramine; Male; Morpholines; Pantothenic Acid; Rats; Rats, Inbred Lew; Theta Rhythm

1986
Adamantanamines and their derivatives as sensitizing agents for 5-hydroxytryptamine-induced contraction of smooth muscle.
    The Journal of pharmacy and pharmacology, 1967, Volume: 19, Issue:3

    Topics: Amantadine; Animals; Cocaine; Dibenzylchlorethamine; Imipramine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neuraminidase; Propylamines; Rats; Sensory Receptor Cells; Serotonin

1967
The toxicologic and pharmacologic properties of amantadine hydrochloride.
    Toxicology and applied pharmacology, 1969, Volume: 15, Issue:3

    Topics: Abnormalities, Drug-Induced; Acetylcholine; Amantadine; Analgesia; Animals; Arrhythmias, Cardiac; Blood Chemical Analysis; Blood Pressure; Central Nervous System; Depression; Dextroamphetamine; Dogs; Drug Synergism; Electrocardiography; Female; Guinea Pigs; Haplorhini; Heart Rate; Histamine; Horses; Humans; Imipramine; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Motor Activity; Nicotine; Norepinephrine; Phenethylamines; Rabbits; Rats; Reproduction; Tetrabenazine; Tritium

1969
[Amantadine. Prolonged clinical trial in 50 parkinsonian patients].
    La Nouvelle presse medicale, 1972, Feb-19, Volume: 1, Issue:8

    Topics: Adult; Aged; Amantadine; Dihydroxyphenylalanine; Drug Synergism; Female; Humans; Imipramine; Male; Middle Aged; Parkinson Disease

1972
[Conservative therapy in the Parkinson syndrome].
    Wiener medizinische Wochenschrift (1946), 1971, Nov-13, Volume: 121, Issue:46

    Topics: Amantadine; Antidepressive Agents; Dihydroxyphenylalanine; Humans; Imipramine; Injections, Intravenous; Movement Disorders; Nausea; Parasympatholytics; Parkinson Disease; Time Factors

1971
Effects of amantadine and of some synthetic antiparkinsonian drugs on the behavioral response to L-DOPA in mice.
    Physiology & behavior, 1971, Volume: 6, Issue:4

    Topics: Amantadine; Amitriptyline; Animals; Antiparkinson Agents; Atropine; Behavior, Animal; Dihydroxyphenylalanine; Diphenhydramine; Drug Synergism; Imipramine; Mice; Orphenadrine; Parasympatholytics; Pargyline; Trihexyphenidyl

1971
Central effects of 6-hydroxydopamine.
    Physiology & behavior, 1971, Volume: 7, Issue:5

    Topics: Amantadine; Amitriptyline; Amphetamine; Animals; Behavior, Animal; Brain; Brain Chemistry; Desipramine; Dopamine; Electroencephalography; Female; Humans; Hydroxydopamines; Imipramine; Male; Mice; Motor Activity; Norepinephrine; Rats; Seizures; Species Specificity; Stereotyped Behavior

1971
Uptake and release of norepinephrine by rat brain tissue fractions prepared by ultrafiltration.
    Journal of neurochemistry, 1971, Volume: 18, Issue:6

    Topics: Amantadine; Animals; Brain; Catecholamines; Cocaine; Cytoplasmic Granules; Dialysis; Filtration; Imipramine; Monoamine Oxidase; Nerve Endings; Norepinephrine; Ouabain; Phenethylamines; Potassium; Rats; Serotonin; Synapses; Synaptic Vesicles; Tritium

1971
Studies on the mechanism of drug-induced lipidosis. Cationic amphiphilic drug inhibition of lysosomal phospholipases A and C.
    Biochemical pharmacology, 1981, May-15, Volume: 30, Issue:10

    Topics: Amantadine; Aniline Compounds; Animals; Chlorphentermine; Chlorpromazine; Heptanes; Imipramine; Lipidoses; Liver; Lysosomes; Male; Pharmacology; Phospholipases; Phospholipases A; Propranolol; Rats; Tripelennamine; Type C Phospholipases

1981
Antidepressant drugs inhibit glucocorticoid receptor-mediated gene transcription - a possible mechanism.
    British journal of pharmacology, 2000, Volume: 130, Issue:6

    Topics: Amantadine; Animals; Antidepressive Agents; Cell Line, Transformed; Chloramphenicol O-Acetyltransferase; Cocaine; Corticosterone; Cyclic AMP; Cyclic GMP; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Estrenes; Gene Expression Regulation; Imipramine; Lithium Chloride; Memantine; Mifepristone; Protein Kinase Inhibitors; Pyrrolidinones; Receptors, Glucocorticoid; Receptors, Steroid; Sulfonamides; Tamoxifen; Thionucleotides; Time Factors; Transcription, Genetic; Type C Phospholipases

2000
[Effect of amantadine or 3-cyclopentyl adamantanamine on the immobility of adult or aged mice, in the forced swim test].
    Annales pharmaceutiques francaises, 2000, Volume: 58, Issue:6

    Topics: Adamantane; Aging; Amantadine; Animals; Antiparkinson Agents; Brain; Imipramine; Male; Mice; Mice, Inbred BALB C; Restraint, Physical; Stress, Psychological; Swimming

2000
Effect of combined treatment with imipramine and amantadine on the central dopamine D2 and D3 receptors in rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2003, Volume: 54, Issue:2

    Topics: Amantadine; Animals; Brain; Drug Therapy, Combination; Imipramine; Male; Protein Binding; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3

2003
'Tako-Tsubo cardiomyopathy' associated with syndrome malin: reversible left ventricular dysfunction.
    Circulation journal : official journal of the Japanese Circulation Society, 2003, Volume: 67, Issue:8

    Topics: 3-Iodobenzylguanidine; Aged; Amantadine; Antidepressive Agents, Tricyclic; Cardiomyopathies; Coronary Angiography; Humans; Imipramine; Male; Neuroleptic Malignant Syndrome; Radionuclide Imaging; Radiopharmaceuticals; Recovery of Function; Thallium Radioisotopes; Ventricular Dysfunction, Left

2003
The effect of combined treatment with imipramine and amantadine on the behavioral reactivity of central alpha1-adrenergic system in rats.
    Behavioural pharmacology, 2004, Volume: 15, Issue:2

    Topics: Administration, Oral; Adrenergic alpha-1 Receptor Agonists; Aggression; Amantadine; Amphetamine; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Binding, Competitive; Cerebral Cortex; Clonidine; Drug Interactions; Drug Therapy, Combination; Exploratory Behavior; Hyperkinesis; Imipramine; Male; Motor Activity; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1

2004
Effect of amantadine and imipramine on immunological parameters of rats subjected to a forced swimming test.
    The international journal of neuropsychopharmacology, 2006, Volume: 9, Issue:3

    Topics: Amantadine; Animals; Cell Proliferation; Corticosterone; Cytokines; Depressive Disorder; Drug Therapy, Combination; Imipramine; Immobilization; Male; Organ Size; Rats; Rats, Wistar; Spleen; Swimming; Thymus Gland

2006
Repeated co-treatment with imipramine and amantadine induces hippocampal brain-derived neurotrophic factor gene expression in rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2007, Volume: 58, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amantadine; Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Drug Therapy, Combination; Gene Expression Regulation; Hippocampus; Imipramine; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Serotonin

2007