Compounds > imipramine

imipramine and 8-hydroxy-2-(di-n-propylamino)tetralin

imipramine has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 60 studies

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.67)18.7374
1990's21 (35.00)18.2507
2000's27 (45.00)29.6817
2010's11 (18.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bartoccini, F; Carminati, P; Castorina, M; Di Cesare, MA; Di Serio, S; Gallo, G; Ghirardi, O; Giorgi, F; Giorgi, L; Minetti, P; Piersanti, G; Tarzia, G; Tinti, MO1
Bojarski, AJ; Chłoń-Rzepa, G; Duszyńska, B; Nikiforuk, A; Pawłowski, M; Tatarczyńska, E; Zajdel, P; Zmudzki, P1
Bugno, R; Chojnacka-Wójcik, E; Duszyńska, B; Lenda, T; Nikiforuk, A; Paluchowska, MH; Tatarczyńska, E1
Buck, LB; Petrascheck, M; Ye, X1
Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG1
Chojnacka-Wójcik, E; Dybała, M; Jurczyk, S; Nikiforuk, A; Nowak, G; Pawłowski, M; Tatarczyńska, E; Zagórska, A1
Colau, D; Dolusić, E; Frédérick, R; Larrieu, P; Masereel, B; Moineaux, L; Pilotte, L; Pochet, L; Stroobant, V; Van den Eynde, B; Wouters, J1
Anzini, M; Brogi, S; Butini, S; Campiani, G; Cappelli, A; Caselli, G; Castriconi, F; Gemma, S; Giordani, A; Giorgi, G; Giuliani, G; Lanza, M; Letari, O; Makovec, F; Manini, M; Mennuni, L; Valenti, S1
Belyakov, S; Dambrova, M; Kazoka, H; Kuznecovs, J; Lebedev, A; Liepinsh, E; Mishnev, A; Orlova, N; Ponomaryov, Y; Vavers, E; Veinberg, G; Vikainis, S; Vilskersts, R; Vorona, M; Zvejniece, L1
Bienkowski, P; Bucki, A; Jaśkowska, J; Kazek, G; Kowalski, P; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Mitka, K; Pawłowski, M; Siwek, A; Wasik, A; Wesołowska, A1
Bojarski, AJ; Bucki, A; Chłoń-Rzepa, G; Jastrzębska-Więsek, M; Kołaczkowski, M; Partyka, A; Satała, G; Wasik, A; Wesołowska, A1
Bienkowski, P; Bucki, A; Jastrzębska-Więsek, M; Kazek, G; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Partyka, A; Pawłowski, M; Siwek, A; Śniecikowska, J; Wasik, A; Wesołowska, A1
Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E1
Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E1
Bączek, T; Belka, M; Bojarski, A; Herold, F; Kleps, J; Kozioł, AE; Król, M; Nowak, G; Siwek, A; Ślifirski, G; Stachowicz, K; Szewczyk, B; Turło, J; Ulenberg, S1
Ben-Zeev, A; Lerer, B; Newman, ME1
Barrett, JE; Zhang, L1
Yamagata, A; Yamaguchi, T1
Blier, P; Chaput, Y; de Montigny, C1
Dragan, YP; Ellis, EF1
Aulakh, CS; Hill, JL; Murphy, DL; Wozniak, KM1
Hayakawa, H; Motohashi, N; Nishida, A; Shimizu, M; Yamawaki, S1
Imaizumi, M; Machida, H; Miyazaki, S1
Klimek, V; Papp, M; Willner, P1
Labow, DM; Tejani-Butt, SM1
Burnet, PW; Gold, PW; Michelson, D; Smith, MA; Sternberg, EM1
Kaviani, A; Tejani-Butt, SM; Yang, J1
McEwen, BS; Mendelson, S; Sakai, RR; Watanabe, Y1
Hashimoto, S; Kasahara, K; Nagatani, T; Takao, K1
Moryl, E; Papp, M; Przegaliński, E1
Morrison, AR; Ross, RJ; Sanford, LD; Tejani-Butt, SM1
Bijak, M; Czyrak, A; Maćkowiak, M; Tokarski, K; Wedzony, K2
Bijak, M; Dziedzicka-Wasylewska, M; Maj, J; Rogoz, R; Rogóz, Z; Skuza, G; Tokarski, T1
Marsden, CA; Mongeau, R1
Leander, JD; Wolff, MC1
Evenden, J; Meyerson, B1
Conway, MW; O'Neill, MF1
Jeanningros, R; Mazzola-Pomietto, P; Moreau, X1
Borsini, F; Brambilla, A; Cesana, R; Grippa, N1
Bijak, M; Tokarski, K; Zahorodna, A2
Arango, V; Boldrini, M; Chen, JJ; Hsiung, S; Kassir, SA; Mann, JJ; Tamir, H; Underwood, MD1
Almeida, LP; Cabral, AH; Jacob, CA; Landeira-Fernandez, J; Magierek, V; Nogueira, RL; Ramos, PL; Zangrossi, H; Zanoveli, JM1
Bijak, M; Hess, G; Zahorodna, A1
Gur, E; Lerer, B; Lifschytz, T; Newman, ME1
Bobula, B; Hess, G; Tokarski, K; Zahorodna, A1
Guimarães, FS; Joca, SR; Padovan, CM1
Araki, H; Gomita, Y; Kitamura, Y; Shibata, K; Tanizaki, Y2
Carvalho-Netto, EF; Nunes-de-Souza, RL1
Gur, E; Lerer, B; Lifschytz, T; Newman, ME; Van De Kar, LD1
Nogueira, RL; Zangrossi, H; Zanoveli, JM1
Hess, G; Tokarski, K; Zahorodna, A1
Hess, G; Zahorodna, A1
Akiyama, K; Araki, H; Gomita, Y; Hashimoto, S; Kawasaki, H; Kitagawa, K; Kitamura, Y; Sendo, T; Shibata, K; Shinomiya, K; Suemaru, K1
Legutko, B; Rogóz, Z; Skuza, G1
Burke, TF; Hensler, JG; Rossi, DV1
Arango, V; Bakalian, MJ; Galfalvy, H; Kassir, SA; Mann, JJ; Underwood, MD1
Haleem, DJ; Samad, N; Yasmin, F1

Other Studies

60 other study(ies) available for imipramine and 8-hydroxy-2-(di-n-propylamino)tetralin

ArticleYear
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.
    Journal of medicinal chemistry, 2005, Nov-03, Volume: 48, Issue:22

    Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cricetinae; Cricetulus; Drug Design; Humans; Imidazoles; Male; Models, Molecular; Motor Activity; Purines; Radioligand Assay; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triazoles

2005
7-Arylpiperazinylalkyl and 7-tetrahydroisoquinolinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and some of their purine-2,6,8-trione analogs as 5-HT(1A), 5-HT(2A), and 5-HT(7) serotonin receptor ligands.
    Bioorganic & medicinal chemistry, 2007, Aug-01, Volume: 15, Issue:15

    Topics: Animals; Body Temperature; Dose-Response Relationship, Drug; Ligands; Male; Mice; Molecular Structure; Motor Activity; Purines; Rats; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Swimming

2007
The influence of modifications in imide fragment structure on 5-HT(1A) and 5-HT(7) receptor affinity and in vivo pharmacological properties of some new 1-(m-trifluoromethylphenyl)piperazines.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Animals; Body Temperature; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Imides; Ligands; Lip; Maze Learning; Mice; Molecular Structure; Motor Activity; Piperazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Stereoisomerism; Structure-Activity Relationship; Swimming

2007
An antidepressant that extends lifespan in adult Caenorhabditis elegans.
    Nature, 2007, Nov-22, Volume: 450, Issue:7169

    Topics: Aging; Animals; Antidepressive Agents; Caenorhabditis elegans; Caloric Restriction; Humans; Longevity; Methiothepin; Mianserin; Octopamine; Receptors, Biogenic Amine; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Starvation

2007
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
    Journal of medicinal chemistry, 2008, Nov-27, Volume: 51, Issue:22

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship

2008
Synthesis and preliminary pharmacological evaluation of imidazo[2,1-f]purine-2,4-dione derivatives.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Animals; Antidepressive Agents; Body Temperature; Cerebral Cortex; Imidazoles; Male; Mice; Molecular Structure; Motor Activity; Piperazines; Protein Binding; Purines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D2; Theophylline

2009
Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.
    Journal of medicinal chemistry, 2011, Aug-11, Volume: 54, Issue:15

    Topics: Animals; Antineoplastic Agents; Biological Availability; Cell Line; Drug Design; Enzyme Inhibitors; Humans; Immunologic Factors; Indoles; Kinetics; Mice; Neoplasms; Structure-Activity Relationship; Tryptophan Oxygenase

2011
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: Animals; Area Under Curve; Humans; Intestinal Absorption; Ligands; Male; Metabolic Clearance Rate; Models, Chemical; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Pyrrolidinones; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship

2013
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.
    Bioorganic & medicinal chemistry, 2013, May-15, Volume: 21, Issue:10

    Topics: Acetamides; Allosteric Regulation; Animals; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism; Structure-Activity Relationship

2013
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia.
    Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Avoidance Learning; Benzoxazoles; Catalepsy; CHO Cells; Cricetulus; Dementia; Dopamine D2 Receptor Antagonists; HEK293 Cells; Humans; Male; Models, Molecular; Motor Activity; Radioligand Assay; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides

2014
Antidepressant- and anxiolytic-like activity of 7-phenylpiperazinylalkyl-1,3-dimethyl-purine-2,6-dione derivatives with diversified 5-HT₁A receptor functional profile.
    Bioorganic & medicinal chemistry, 2015, Jan-01, Volume: 23, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Mice; Purines; Receptor, Serotonin, 5-HT1A; Structure-Activity Relationship

2015
Novel 5-HT6 receptor antagonists/D2 receptor partial agonists targeting behavioral and psychological symptoms of dementia.
    European journal of medicinal chemistry, 2015, Mar-06, Volume: 92

    Topics: Animals; Benzamides; Dementia; Dose-Response Relationship, Drug; Drug Partial Agonism; Humans; Indoles; Ligands; Male; Models, Molecular; Molecular Structure; Piperazines; Quinolones; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin; Structure-Activity Relationship; Swimming

2015
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
    Bioorganic & medicinal chemistry, 2016, Apr-15, Volume: 24, Issue:8

    Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Drug Design; Epilepsy; Male; Mice; Microsomes, Liver; Molecular Structure; Pilocarpine

2016
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
    Bioorganic & medicinal chemistry, 2017, 01-15, Volume: 25, Issue:2

    Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship

2017
Synthesis of novel pyrido[1,2-c]pyrimidine derivatives with rigidized tryptamine moiety as potential SSRI and 5-HT
    European journal of medicinal chemistry, 2019, Mar-15, Volume: 166

    Topics: Animals; Chemistry Techniques, Synthetic; Drug Design; Ligands; Mice; Pyrimidines; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Tryptamines

2019
Chloroamphetamine did not prevent the effects of chronic antidepressants on 5-hydroxytryptamine inhibition of forskolin-stimulated adenylate cyclase in rat hippocampus.
    European journal of pharmacology, 1991, Jul-12, Volume: 207, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Antidepressive Agents; Binding Sites; Cerebral Cortex; Chlorides; Colforsin; Hippocampus; Imipramine; Lithium; Lithium Chloride; Male; p-Chloroamphetamine; Paroxetine; Piperidines; Rats; Serotonin; Synapses; Tetrahydronaphthalenes

1991
Involvement of 5-HT1A activity in the discriminative stimulus effects of imipramine.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Tricyclic; Columbidae; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Imipramine; Male; Piperazines; Prazosin; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes

1991
Serotonergic ligand binding in aging brain of experimental animals.
    Neurochemical research, 1991, Volume: 16, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Aging; Animals; Brain; Cell Membrane; Cerebellum; Choline; Hippocampus; Imipramine; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Species Specificity; Tetrahydronaphthalenes

1991
Presynaptic and postsynaptic modifications of the serotonin system by long-term administration of antidepressant treatments. An in vivo electrophysiologic study in the rat.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1991, Volume: 5, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Electric Stimulation; Electrophysiology; Hippocampus; Imipramine; Male; Neurons; Paroxetine; Piperidines; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synapses; Tetrahydronaphthalenes

1991
5-Hydroxytryptamine and the metabolism of arachidonic acid by the lipoxygenase and cyclooxygenase of washed human platelets.
    Biochemical pharmacology, 1990, Jul-15, Volume: 40, Issue:2

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Humans; Hydroxyeicosatetraenoic Acids; Imipramine; In Vitro Techniques; Lipoxygenase; Prostaglandin-Endoperoxide Synthases; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes

1990
Differential effects of long-term antidepressant treatments on 8-OHDPAT-induced increases in plasma prolactin and corticosterone in rats.
    European journal of pharmacology, 1988, Nov-08, Volume: 156, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Clomipramine; Clorgyline; Corticosterone; Imipramine; Male; Naphthalenes; Prolactin; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes; Time Factors

1988
Increase in serotonin 1A receptors in the dentate gyrus as revealed by autoradiographic analysis following repeated electroconvulsive shock but not imipramine treatment.
    Neuropsychobiology, 1994, Volume: 30, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain Mapping; Electroshock; Hippocampus; Imipramine; Male; Rats; Rats, Wistar; Receptors, Serotonin

1994
Discriminative stimulus properties of diazepam and the novel anxiolytic agent 1-amino-5-bromouracil in rats.
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:10

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Bromouracil; Clonidine; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Generalization, Stimulus; Imipramine; Male; Rats; Rats, Wistar

1994
Effects of imipramine on serotonergic and beta-adrenergic receptor binding in a realistic animal model of depression.
    Psychopharmacology, 1994, Volume: 114, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Depression; Dihydroalprenolol; Imipramine; Ketanserin; Kinetics; Male; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Serotonin; Stress, Psychological

1994
Time course of the effects of adrenalectomy and corticosterone replacement on 5-HT1A receptors and 5-HT uptake sites in the hippocampus and dorsal raphe nucleus of the rat brain: an autoradiographic analysis.
    Psychopharmacology, 1994, Volume: 113, Issue:3-4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenalectomy; Animals; Autoradiography; Corticosterone; Hippocampus; Imipramine; Male; Pyramidal Cells; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Time Factors

1994
The effect of chronic imipramine administration on the densities of 5-HT1A and 5-HT2 receptors and the abundances of 5-HT receptor and transporter mRNA in the cortex, hippocampus and dorsal raphe of three strains of rat.
    Brain research, 1994, Feb-28, Volume: 638, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Carrier Proteins; Cerebral Cortex; Drug Administration Schedule; Female; Gene Expression; Hippocampus; Imipramine; In Situ Hybridization; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Organ Specificity; Pyramidal Cells; Raphe Nuclei; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Sprague-Dawley; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Plasma Membrane Transport Proteins; Species Specificity; Tritium

1994
Time course of altered thyroid states on 5-HT1A receptors and 5-HT uptake sites in rat brain: an autoradiographic analysis.
    Neuroendocrinology, 1993, Volume: 57, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Body Weight; Brain Chemistry; Hyperthyroidism; Imipramine; Kinetics; Male; Radioimmunoassay; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Tetrodotoxin; Thyroid Gland; Thyroidectomy; Thyroxine; Triiodothyronine

1993
Stress and antidepressant effects on hippocampal and cortical 5-HT1A and 5-HT2 receptors and transport sites for serotonin.
    Brain research, 1993, Jun-25, Volume: 615, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Autoradiography; Carrier Proteins; Cerebral Cortex; Corticosterone; Hippocampus; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Restraint, Physical; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stress, Psychological; Thiazepines

1993
Role of 5-HT1A receptors in the forced swimming wheel test in reserpine-treated mice.
    Life sciences, 1993, Volume: 52, Issue:22

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Dose-Response Relationship, Drug; Drug Interactions; Imipramine; Male; Mice; Mice, Inbred ICR; Motor Activity; Propranolol; Receptors, Serotonin; Reserpine; Swimming

1993
The effect of 5-HT1A receptor ligands in a chronic mild stress model of depression.
    Neuropharmacology, 1995, Volume: 34, Issue:10

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Citalopram; Depressive Disorder; Disease Models, Animal; Imipramine; Male; Rats; Rats, Wistar; Receptors, Serotonin; Time Factors

1995
Elicited PGO waves in rats: lack of 5-HT1A inhibition in putative pontine generator region.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 53, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Electric Stimulation; Electroencephalography; Geniculate Bodies; Imipramine; Male; Microinjections; Occipital Lobe; Pons; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

1996
Imipramine increases the 5-HT1A receptor-mediated inhibition of hippocampal neurons without changing the 5-HT1A receptor binding.
    European journal of pharmacology, 1996, Jun-03, Volume: 305, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Tricyclic; Autoradiography; Baclofen; Binding, Competitive; Electric Stimulation; GABA Agonists; Hippocampus; Imipramine; Male; Neural Inhibition; Protein Binding; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists

1996
The effects of paroxetine given repeatedly on the 5-HT receptor subpopulations in the rat brain.
    Psychopharmacology, 1996, Volume: 127, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain Chemistry; Electrophysiology; Hippocampus; Imipramine; Male; Motor Activity; Paroxetine; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists

1996
Prolonged treatment with antidepressants increases the 5-HT1A-mediated inhibition of hippocampal neurons without changing the 5-HT1A receptor binding.
    Acta physiologica Hungarica, 1996, Volume: 84, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Electric Stimulation; Hippocampus; Imipramine; In Vitro Techniques; Male; Neural Inhibition; Neurons; Rats; Rats, Wistar; Receptors, Serotonin; Time Factors

1996
Effect of imipramine treatments on the 5-HT1A-receptor-mediated inhibition of panic-like behaviours in rats.
    Psychopharmacology, 1997, Volume: 131, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; Escape Reaction; Homocysteine; Imipramine; Male; Panic Disorder; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Substance Withdrawal Syndrome

1997
Selective serotonin reuptake inhibitors potentiate 8-OH-DPAT-induced stimulus control in the pigeon.
    European journal of pharmacology, 1998, Mar-12, Volume: 345, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Citalopram; Columbidae; Conditioning, Operant; Discrimination, Psychological; Drug Synergism; Fluoxetine; Generalization, Stimulus; Imipramine; Male; Neurotransmitter Uptake Inhibitors; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists

1998
The behavior of spontaneously hypertensive and Wistar Kyoto rats under a paced fixed consecutive number schedule of reinforcement.
    Pharmacology, biochemistry, and behavior, 1999, Volume: 63, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Chlordiazepoxide; Conditioning, Operant; Dextroamphetamine; Haloperidol; Hypertension; Imipramine; Piperazines; Psychotropic Drugs; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reinforcement Schedule; Species Specificity

1999
Role of 5-HT(1A) and 5-HT(1B) receptors in the mediation of behavior in the forced swim test in mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 24, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Dose-Response Relationship, Drug; Female; Imipramine; Indoles; Mice; Mice, Inbred Strains; Motor Activity; Oxadiazoles; Piperazines; Piperidines; Pyridines; Reaction Time; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming

2001
Chronic effects of triiodothyronine in combination with imipramine on 5-HT transporter, 5-HT(1A) and 5-HT(2A) receptors in adult rat brain.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 24, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Tricyclic; Body Weight; Brain; Carrier Proteins; Citalopram; Depressive Disorder; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Imipramine; Ketanserin; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Radioligand Assay; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Thyroid Gland; Time Factors; Triiodothyronine

2001
Lack of interaction between flibanserin and antidepressants in inducing serotonergic syndrome in rats.
    The international journal of neuropsychopharmacology, 2001, Volume: 4, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Benzimidazoles; Drug Interactions; Fluoxetine; Imipramine; Male; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Serotonin Syndrome

2001
Opposite effects of antidepressants and corticosterone on the sensitivity of hippocampal CA1 neurons to 5-HT1A and 5-HT4 receptor activation.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Corticosterone; Electroshock; Free Radical Scavengers; Hippocampus; Imipramine; Male; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2001
Serotonin 1A receptors, serotonin transporter binding and serotonin transporter mRNA expression in the brainstem of depressed suicide victims.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 25, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adult; Aged; Aged, 80 and over; Autoradiography; Brain Stem; Carrier Proteins; Depressive Disorder; Female; Humans; Hydrogen-Ion Concentration; Imipramine; In Situ Hybridization; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Raphe Nuclei; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; RNA, Messenger; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Sex Characteristics; Suicide

2001
Imipramine but not 5-HT(1A) receptor agonists or neuroleptics induces adaptive changes in hippocampal 5-HT(1A) and 5-HT(4) receptors.
    European journal of pharmacology, 2002, May-17, Volume: 443, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Antidepressive Agents; Antipsychotic Agents; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Clozapine; Haloperidol; Hippocampus; Imipramine; In Vitro Techniques; Male; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists

2002
Chronic imipramine enhances 5-HT(1A) and 5-HT(2) receptors-mediated inhibition of panic-like behavior in the rat dorsal periaqueductal gray.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 72, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Avoidance Learning; Electric Stimulation; Escape Reaction; Female; Imipramine; Microinjections; Panic; Periaqueductal Gray; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists

2002
Differential effects of repeated imipramine on hippocampal responsiveness to adenosine and serotonin.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2002, Volume: 12, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenosine; Adrenergic Uptake Inhibitors; Animals; Drug Administration Schedule; Drug Interactions; Excitatory Postsynaptic Potentials; Hippocampus; Imipramine; In Vitro Techniques; Membrane Potentials; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Signal Transduction

2002
Effects of triiodothyronine and imipramine on basal 5-HT levels and 5-HT(1) autoreceptor activity in rat cortex.
    European journal of pharmacology, 2002, Dec-13, Volume: 457, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Tricyclic; Autoreceptors; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Synergism; Imipramine; Male; Rats; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Triiodothyronine

2002
Adaptive changes in the reactivity of 5-HT1A and 5-HT2 receptors induced in rat frontal cortex by repeated imipramine and citalopram.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 367, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adaptation, Physiological; Administration, Topical; Amphetamines; Animals; Benzamides; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Citalopram; Cortical Synchronization; Dose-Response Relationship, Drug; Frontal Lobe; Imipramine; Male; Neurons; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT2

2003
Activation of post-synaptic 5-HT(1A) receptors in the dorsal hippocampus prevents learned helplessness development.
    Brain research, 2003, Jul-18, Volume: 978, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Drug Administration Schedule; Drug Interactions; Escape Reaction; Helplessness, Learned; Hippocampus; Imipramine; Male; Piperazines; Pyridines; Rats; Rats, Wistar; Reaction Time; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Physiological; Zimeldine

2003
5-HT(1A) receptor full agonist, 8-OH-DPAT, exerts antidepressant-like effects in the forced swim test in ACTH-treated rats.
    European journal of pharmacology, 2003, Nov-14, Volume: 481, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Dose-Response Relationship, Drug; Imipramine; Male; Rats; Rats, Wistar; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Swimming

2003
Modulation of 8-OH-DPAT-induced hypothermia by imipramine in rats.
    Journal of pharmacological sciences, 2003, Volume: 93, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Drug Synergism; Hypothermia; Hypothermia, Induced; Imipramine; Male; Rats; Rats, Wistar

2003
Use of the elevated T-maze to study anxiety in mice.
    Behavioural brain research, 2004, Jan-05, Volume: 148, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Appetite Depressants; Avoidance Learning; Caffeine; Carbolines; Central Nervous System Stimulants; Conditioning, Classical; Dose-Response Relationship, Drug; Escape Reaction; Imipramine; Inhibition, Psychological; Male; Maze Learning; Mice; Motor Activity; Random Allocation; Reaction Time; Serotonin Agents; Yohimbine

2004
Effects of triiodothyronine on 5-HT(1A) and 5-HT(1B) autoreceptor activity, and postsynaptic 5-HT(1A) receptor activity, in rat hypothalamus: lack of interaction with imipramine.
    Psychoneuroendocrinology, 2004, Volume: 29, Issue:9

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Autoreceptors; Corticosterone; Drug Interactions; Hypothalamus; Imipramine; Male; Microdialysis; Microinjections; Rats; Rats, Inbred Strains; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Serotonin Receptor Agonists; Synaptic Transmission; Triiodothyronine

2004
Chronic imipramine treatment sensitizes 5-HT1A and 5-HT 2 A receptors in the dorsal periaqueductal gray matter: evidence from the elevated T-maze test of anxiety.
    Behavioural pharmacology, 2005, Volume: 16, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antidepressive Agents, Tricyclic; Anxiety; Buspirone; Imipramine; Male; Motor Activity; Periaqueductal Gray; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin Receptor Agonists

2005
Imipramine treatment ameliorates corticosterone-induced alterations in the effects of 5-HT1A and 5-HT4 receptor activation in the CA1 area of rat hippocampus.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2006, Volume: 16, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Tricyclic; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Corticosterone; Electric Stimulation; Hippocampus; Imipramine; In Vitro Techniques; Male; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists

2006
Imipramine and citalopram reverse corticosterone-induced alterations in the effects of the activation of 5-HT(1A) and 5-HT(2) receptors in rat frontal cortex.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2006, Volume: 57, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Citalopram; Corticosterone; Depression; Frontal Lobe; Imipramine; Male; Models, Animal; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT2; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Psychological

2006
Effects of imipramine on extracellular serotonin and noradrenaline concentrations in ACTH-treated rats.
    European journal of pharmacology, 2007, Jul-02, Volume: 566, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Adrenocorticotropic Hormone; Animals; Antidepressive Agents, Tricyclic; Corticosterone; Imipramine; Male; Norepinephrine; Prefrontal Cortex; Rats; Rats, Wistar; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists

2007
Repeated co-treatment with imipramine and amantadine induces hippocampal brain-derived neurotrophic factor gene expression in rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2007, Volume: 58, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amantadine; Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Drug Therapy, Combination; Gene Expression Regulation; Hippocampus; Imipramine; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Serotonin

2007
Differential regulation of serotonin-1A receptor-stimulated [35S]GTP gamma S binding in the dorsal raphe nucleus by citalopram and escitalopram.
    European journal of pharmacology, 2008, Mar-31, Volume: 583, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Binding, Competitive; Citalopram; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Imipramine; In Vitro Techniques; Male; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists

2008
Neuron density and serotonin receptor binding in prefrontal cortex in suicide.
    The international journal of neuropsychopharmacology, 2012, Volume: 15, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adolescent; Adult; Aged; Autoradiography; Case-Control Studies; Depressive Disorder, Major; Female; Humans; Imipramine; Ketanserin; Male; Middle Aged; Neurons; Postmortem Changes; Prefrontal Cortex; Protein Binding; Receptors, Serotonin; Serotonin Agents; Suicide; Tritium; Up-Regulation; Young Adult

2012
Co-treatment with imipramine averted haloperidol-instigated tardive dyskinesia: Association with serotonin in brain regions.
    Pakistan journal of pharmaceutical sciences, 2016, Volume: 29, Issue:6 Suppl

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain; Disease Models, Animal; Haloperidol; Imipramine; Male; Mastication; Motor Activity; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin and Noradrenaline Reuptake Inhibitors; Tardive Dyskinesia; Time Factors

2016