Page last updated: 2024-09-04

imiloxan and prazosin

imiloxan has been researched along with prazosin in 5 studies

Compound Research Comparison

Studies
(imiloxan)
Trials
(imiloxan)
Recent Studies (post-2010)
(imiloxan)
Studies
(prazosin)
Trials
(prazosin)
Recent Studies (post-2010) (prazosin)
450217,914713682

Protein Interaction Comparison

ProteinTaxonomyimiloxan (IC50)prazosin (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)5.87
Interstitial collagenaseHomo sapiens (human)4.036
Alpha-2A adrenergic receptorHomo sapiens (human)2.638
Matrix metalloproteinase-9Homo sapiens (human)6.963
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0008
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)0.0078
Alpha-2B adrenergic receptorHomo sapiens (human)0.29
Alpha-2C adrenergic receptorHomo sapiens (human)0.647
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0008
Alpha-1D adrenergic receptorHomo sapiens (human)0.0007
Bromodomain-containing protein 2Homo sapiens (human)0.0009
Alpha-1A adrenergic receptorHomo sapiens (human)0.0006
Alpha-1B adrenergic receptorHomo sapiens (human)0.0006
5-hydroxytryptamine receptor 2BHomo sapiens (human)4.118
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0008
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)9.9
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.5849
Multidrug and toxin extrusion protein 1Homo sapiens (human)1.6

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Butler, RC; Chapleo, CB; Doxey, JC; Myers, PL; Roach, AG; Smith, CF1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Flavahan, NA; Grant, TL; Greig, J; McGrath, JC; McKean, CE; Reid, JL1
Saxena, PR; Valdivia, LF; Villalón, CM; Willems, EW1
Arulmani, U; Centurión, D; Saxena, PR; Valdivia, LF; Villalón, CM1

Other Studies

5 other study(ies) available for imiloxan and prazosin

ArticleYear
alpha-adrenoreceptor reagents. 1. Synthesis of some 1,4-benzodioxans as selective presynaptic alpha 2-adrenoreceptor antagonists and potential antidepressants.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Dioxins; Dose-Response Relationship, Drug; Idazoxan; Male; Mice; Phenylephrine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Synapses; Vas Deferens

1983
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Attempts to uncover subtypes of alpha-adrenoceptors and associated mechanisms by using sequential administration of blocking drugs.
    Clinical science (London, England : 1979), 1985, Volume: 68 Suppl 10

    Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Imidazoles; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Propranolol; Rabbits; Rats; Receptors, Adrenergic, alpha; Synaptic Transmission; Yohimbine

1985
The role of several alpha(1)- and alpha(2)-adrenoceptor subtypes mediating vasoconstriction in the canine external carotid circulation.
    British journal of pharmacology, 2001, Volume: 132, Issue:6

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Carotid Artery, External; Dogs; Female; Imidazoles; Indoles; Isoindoles; Male; Phenylephrine; Piperazines; Prazosin; Quinolizines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Regional Blood Flow; Vasoconstriction

2001
5-HT1B receptors, alpha2A/2C- and, to a lesser extent, alpha1-adrenoceptors mediate the external carotid vasoconstriction to ergotamine in vagosympathectomised dogs.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:1

    Topics: Animals; Biphenyl Compounds; Blood Pressure; Carotid Artery, External; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Ergotamine; Hypotension; Imidazoles; Indoles; Injections, Intravenous; Isoindoles; Male; Piperazines; Piperidones; Prazosin; Quinolizines; Receptor, Serotonin, 5-HT1B; Receptors, Adrenergic, alpha; Regional Blood Flow; Spiro Compounds; Sympathectomy; Vagotomy; Vasoconstriction; Yohimbine

2004