Page last updated: 2024-09-04

imiloxan and idazoxan

imiloxan has been researched along with idazoxan in 7 studies

Compound Research Comparison

Studies
(imiloxan)
Trials
(imiloxan)
Recent Studies (post-2010)
(imiloxan)
Studies
(idazoxan)
Trials
(idazoxan)
Recent Studies (post-2010) (idazoxan)
450211,49940123

Protein Interaction Comparison

ProteinTaxonomyimiloxan (IC50)idazoxan (IC50)
Alpha-2A adrenergic receptorHomo sapiens (human)0.0083
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0195
Alpha-2B adrenergic receptorHomo sapiens (human)0.0195
Alpha-2C adrenergic receptorHomo sapiens (human)0.0537
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0195
Alpha-1A adrenergic receptorHomo sapiens (human)2.884
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0195

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Butler, RC; Chapleo, CB; Doxey, JC; Myers, PL; Roach, AG; Smith, CF1
Davidson, JM; Kwong, LL; Peroutka, SJ; Smith, ER1
Davidson, JM; Lee, RL; Schnur, SL; Smith, ER2
de Castro Perez, A; de Francischi, JN; Gama Duarte, ID; Romero, TR1
Khisamieva, LI; Zefirov, AL; Zefirov, TL; Ziyatdinova, NI2

Other Studies

7 other study(ies) available for imiloxan and idazoxan

ArticleYear
alpha-adrenoreceptor reagents. 1. Synthesis of some 1,4-benzodioxans as selective presynaptic alpha 2-adrenoreceptor antagonists and potential antidepressants.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Dioxins; Dose-Response Relationship, Drug; Idazoxan; Male; Mice; Phenylephrine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Synapses; Vas Deferens

1983
Differential interactions of "prosexual" drugs with 5-hydroxytryptamine1A and alpha 2-adrenergic receptors.
    Behavioral neuroscience, 1986, Volume: 100, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Brain; Dioxanes; Ejaculation; Idazoxan; Imidazoles; Indans; Male; Methoxydimethyltryptamines; Rats; Receptors, Adrenergic, alpha; Receptors, Serotonin; Stimulation, Chemical; Tetrahydronaphthalenes; Yohimbine

1986
Alpha 2-adrenoceptor antagonists and male sexual behavior: II. Erectile and ejaculatory reflexes.
    Physiology & behavior, 1987, Volume: 41, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Ejaculation; Idazoxan; Imidazoles; Male; Penile Erection; Rats; Reflex; Sexual Behavior, Animal; Yohimbine

1987
Alpha 2-adrenoceptor antagonists and male sexual behavior: I. Mating behavior.
    Physiology & behavior, 1987, Volume: 41, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dose-Response Relationship, Drug; Idazoxan; Imidazoles; Male; Rats; Sexual Behavior, Animal; Yohimbine

1987
Probable involvement of alpha(2C)-adrenoceptor subtype and endogenous opioid peptides in the peripheral antinociceptive effect induced by xylazine.
    European journal of pharmacology, 2009, Apr-17, Volume: 608, Issue:1-3

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Dinoprostone; Dose-Response Relationship, Drug; Hyperalgesia; Idazoxan; Imidazoles; Leucine; Male; Naloxone; Opioid Peptides; Pain; Pain Measurement; Rats; Rats, Wistar; Xylazine; Yohimbine

2009
Peculiar Effects of Selective Blockade of α2-Adrenoceptor Subtypes on Cardiac Chronotropy in Newborn Rats.
    Bulletin of experimental biology and medicine, 2015, Volume: 160, Issue:1

    Topics: Acridines; Adrenergic alpha-2 Receptor Antagonists; Animals; Animals, Newborn; Heart; Heart Conduction System; Heart Rate; Idazoxan; Imidazoles; Myocardial Contraction; Piperazines; Rats; Receptors, Adrenergic, alpha-2; Receptors, Presynaptic; Tachycardia

2015
Selective Blockade of α
    Bulletin of experimental biology and medicine, 2016, Volume: 162, Issue:2

    Topics: Acridines; Adrenergic alpha-2 Receptor Antagonists; Animals; Animals, Outbred Strains; Dose-Response Relationship, Drug; Heart Atria; Heart Ventricles; Idazoxan; Imidazoles; Myocardial Contraction; Piperazines; Rats; Receptors, Adrenergic, alpha-2; Tissue Culture Techniques

2016