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imidazolyl-4-propylamine and histamine

imidazolyl-4-propylamine has been researched along with histamine in 6 studies

*Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. [MeSH]

*Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. [MeSH]

Compound Research Comparison

Studies
(imidazolyl-4-propylamine)
Trials
(imidazolyl-4-propylamine)
Recent Studies (post-2010)
(imidazolyl-4-propylamine)
Studies
(histamine)
Trials
(histamine)
Recent Studies (post-2010) (histamine)
60037,7181,3723,457

Protein Interaction Comparison

ProteinTaxonomyimidazolyl-4-propylamine (IC50)histamine (IC50)
Histamine H1 receptorRattus norvegicus (Norway rat)0.1585
Histamine H1 receptorHomo sapiens (human)0.1585

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Leurs, R; Menge, WM; Timmerman, H; Vollinga, RC1
Bakker, R; Cavoy, E; De Esch, IJ; Deltent, MF; Kitbunnadaj, R; Leurs, R; Lutz, M; Menge, WM; Spek, AL; Timmerman, H; Vollinga, RC; Zuiderveld, OP1
Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM1
Buschauer, A; Dove, S; Igel, P1
Banning, JW; Dipietro, RA; Griffith, RK1
Beck, P; Cesario, C; Mulvihill, MJ; Nigro, A; Smith, V1

Other Studies

6 other study(ies) available for imidazolyl-4-propylamine and histamine

ArticleYear
Homologs of histamine as histamine H3 receptor antagonists: a new potent and selective H3 antagonist, 4(5)-(5-aminopentyl)-1H-imidazole.
    Journal of medicinal chemistry, 1995, Jan-20, Volume: 38, Issue:2

    Topics: Animals; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; Jejunum; Magnetic Resonance Spectroscopy; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Structure-Activity Relationship

1995
Synthesis and structure-activity relationships of conformationally constrained histamine H(3) receptor agonists.
    Journal of medicinal chemistry, 2003, Dec-04, Volume: 46, Issue:25

    Topics: Binding, Competitive; Cell Line; Colorimetry; Crystallography, X-Ray; Cyclic AMP; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Imidazoles; Ligands; Molecular Conformation; Piperidines; Pyrrolidines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship

2003
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3

    Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4

2005
Histamine H4 receptor agonists.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Animals; Benzimidazoles; Binding Sites; Clozapine; Guanidines; Humans; Ligands; Mice; Oximes; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship

2010
Histamine receptor activation by unsaturated (allyl and propargyl) homologs of histamine.
    Agents and actions, 1985, Volume: 17, Issue:2

    Topics: Adrenergic Fibers; Animals; Cimetidine; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Muscle Contraction; Myocardial Contraction; Propranolol; Pyrilamine; Receptors, Histamine

1985
Regio- and stereospecific syntheses of syn- and anti-1,2-imidazolylpropylamines from the reaction of 1,1'-carbonyldiimidazole with syn- and anti-1,2-amino alcohols.
    The Journal of organic chemistry, 2004, Jul-23, Volume: 69, Issue:15

    Topics: Amino Alcohols; Histamine; Imidazoles; Molecular Structure; Oxidation-Reduction; Stereoisomerism

2004