imidazole and pyrimidinones

imidazole has been researched along with pyrimidinones in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (33.33)	29.6817
2010's	2 (66.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Doherty, JB; Natarajan, SR	1
Basarab, GS; Eyermann, CJ; Gowravaram, M; Hill, P; Käck, H; Osimoni, E	1
Alonso de Diego, SA; Bartolomé-Nebreda, JM; Bridges, TM; Conde-Ceide, S; Conn, PJ; Daniels, JS; Jones, CK; Lavreysen, H; Lindsley, CW; López, S; Macdonald, GJ; Mackie, C; Martín-Martín, ML; Martínez-Viturro, CM; Niswender, CM; Noetzel, MJ; Stauffer, SR; Steckler, T; Tong, HM	1

Reviews

1 review(s) available for imidazole and pyrimidinones

Article	Year
P38 MAP kinase inhibitors: evolution of imidazole-based and pyrido-pyrimidin-2-one lead classes. Current topics in medicinal chemistry, 2005, Volume: 5, Issue:10 Topics: Binding Sites; Drug Design; Enzyme Inhibitors; Imidazoles; p38 Mitogen-Activated Protein Kinases; Pyridazines; Pyrimidines; Pyrimidinones; Structure-Activity Relationship	2005

Other Studies

2 other study(ies) available for imidazole and pyrimidinones

Article	Year
Design of inhibitors of Helicobacter pylori glutamate racemase as selective antibacterial agents: incorporation of imidazoles onto a core pyrazolopyrimidinedione scaffold to improve bioavailabilty. Bioorganic & medicinal chemistry letters, 2012, Sep-01, Volume: 22, Issue:17 Topics: Administration, Oral; Amino Acid Isomerases; Animals; Anti-Bacterial Agents; Biological Availability; Helicobacter Infections; Helicobacter pylori; Humans; Imidazoles; Mice; Models, Molecular; Pyrazoles; Pyrimidinones; Structure-Activity Relationship	2012
Discovery and SAR of novel series of imidazopyrimidinones and dihydroimidazopyrimidinones as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5). Bioorganic & medicinal chemistry letters, 2015, Mar-15, Volume: 25, Issue:6 Topics: Allosteric Regulation; Animals; Antipsychotic Agents; Brain; Drug Evaluation, Preclinical; Half-Life; Heterocyclic Compounds, 2-Ring; Humans; Imidazoles; Locomotion; Microsomes, Liver; Protein Binding; Pyrimidinones; Rats; Receptor, Metabotropic Glutamate 5; Structure-Activity Relationship	2015

Article

Year

Design of inhibitors of Helicobacter pylori glutamate racemase as selective antibacterial agents: incorporation of imidazoles onto a core pyrazolopyrimidinedione scaffold to improve bioavailabilty.

Bioorganic & medicinal chemistry letters, 2012, Sep-01, Volume: 22, Issue:17

Topics: Administration, Oral; Amino Acid Isomerases; Animals; Anti-Bacterial Agents; Biological Availability; Helicobacter Infections; Helicobacter pylori; Humans; Imidazoles; Mice; Models, Molecular; Pyrazoles; Pyrimidinones; Structure-Activity Relationship

2012

Discovery and SAR of novel series of imidazopyrimidinones and dihydroimidazopyrimidinones as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5).

Bioorganic & medicinal chemistry letters, 2015, Mar-15, Volume: 25, Issue:6

Topics: Allosteric Regulation; Animals; Antipsychotic Agents; Brain; Drug Evaluation, Preclinical; Half-Life; Heterocyclic Compounds, 2-Ring; Humans; Imidazoles; Locomotion; Microsomes, Liver; Protein Binding; Pyrimidinones; Rats; Receptor, Metabotropic Glutamate 5; Structure-Activity Relationship

2015