imidazole has been researched along with pyrimidine in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 10 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashi, M; Iguchi, Y; Iizuka, K; Kajiwara, I; Kawamura, M; Miyamoto, T; Nakazawa, M; Ohyama, I; Okada, T; Taniguchi, K; Tanouchi, T | 1 |
| Fotsch, C; St Jean, DJ | 1 |
| Cai, D; Dormer, PG; Hoerrner, RS; Javadi, GJ; Jensen, MS; Larsen, RD; Li, W; Nelson, DP | 1 |
| Ahmad, K; Beg, Y; Cho, SJ; Muddassar, M; Pasha, FA | 1 |
| Barbachyn, MR; Cai, H; Chen, H; Gage, JW; Hanna, DL; Huband, MD; Lall, MS; Lockard, M; McCurdy, SP; Mullins, LM; Owen, RM; Rauckhorst, MR; Sciotti, RJ; Starr, JT; Tomilo, M | 1 |
| Frimurer, TM; Grimstrup, M; Högberg, T; Mathiesen, JM; Nielsen, PA; Receveur, JM; Rist, Ø | 1 |
| Antonini, I; Buccioni, M; Cristalli, G; Dal Ben, D; Lambertucci, C; Marucci, G; Thomas, A; Volpini, R | 1 |
| Bonaccorso, C; Carlotti, B; Fortuna, CG; Mazzoli, A; Mazzucato, U; Miolo, G; Spalletti, A | 1 |
| Andrei, G; Balzarini, J; Johnson, C; Krishnamoorthy, P; Seley-Radtke, KL; Snoeck, R; Wauchope, OR | 1 |
| Liang, H; Xiao, S | 1 |
| Atwal, K; Blanar, M; Caringal, Y; Conder, ML; Finlay, HJ; Harper, T; Hsueh, MM; Jiang, J; Kover, A; Levesque, P; Lloyd, J; Wexler, R; Xing, D | 1 |
| Dharmaraja, J; Narayan, A; Shobana, S; Subramaniam, P | 1 |
| Carlson, HA; Goh, GB; Lexa, KW | 1 |
| Bajda, M; Bednarski, M; Bucki, A; Czopek, A; Głuch-Lutwin, M; Jastrzębska-Więsek, M; Jończyk, J; Koczurkiewicz, P; Kołaczkowski, M; Partyka, A; Pawłowski, M; Piska, K; Siwek, A; Wesołowska, A; Zagórska, A | 1 |
2 review(s) available for imidazole and pyrimidine
| Article | Year |
|---|---|
Mitigating heterocycle metabolism in drug discovery.
Topics: Animals; Biotransformation; Databases, Factual; Drug Discovery; Drug Interactions; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Pharmaceutical Preparations; Rats | 2012 |
Neuropeptide S receptor: recent updates on nonpeptide antagonist discovery.
Topics: Calcium; Cyclic AMP; Furans; Humans; Imidazoles; Models, Molecular; Neuropeptides; Pyrimidines; Quinolones; Receptors, G-Protein-Coupled | 2011 |
12 other study(ies) available for imidazole and pyrimidine
| Article | Year |
|---|---|
Highly selective inhibitors of thromboxane synthetase. 2. Pyridine derivatives.
Topics: Animals; Oxidoreductases; Pyridines; Sheep; Structure-Activity Relationship; Thromboxane-A Synthase | 1981 |
Efficient synthesis of a GABA A alpha2,3-selective allosteric modulator via a sequential Pd-catalyzed cross-coupling approach.
Topics: Allosteric Regulation; Boronic Acids; Catalysis; GABA Agonists; Imidazoles; Molecular Structure; Oxidation-Reduction; Palladium; Propanols; Pyridines; Pyrimidines; Stereoisomerism | 2005 |
3D and quantum QSAR of non-benzodiazepine compounds.
Topics: Benzodiazepines; Carbolines; Imaging, Three-Dimensional; Imidazoles; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Pyrimidines; Quantitative Structure-Activity Relationship; Software | 2008 |
5-(2-Pyrimidinyl)-imidazo[1,2-a]pyridines are antibacterial agents targeting the ATPase domains of DNA gyrase and topoisomerase IV.
Topics: Animals; Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Gram-Positive Bacteria; Imidazoles; Lung; Mice; Microbial Sensitivity Tests; Pyridines; Pyrimidines; Rats; Sepsis; Structure-Activity Relationship | 2009 |
Exploration of SAR features by modifications of thiazoleacetic acids as CRTH2 antagonists.
Topics: Animals; Benzhydryl Compounds; Binding Sites; Cell Line; Computer Simulation; Humans; Hydrogen Bonding; Imidazoles; Mice; Models, Molecular; Nitrogen; Pyrimidines; Rats; Receptors, Immunologic; Receptors, Prostaglandin; Structure-Activity Relationship; Thiazoles | 2010 |
Photochemistry and DNA-affinity of some pyrimidine-substituted styryl-azinium iodides.
Topics: Circular Dichroism; DNA; Imidazoles; Iodides; Isomerism; Pyridinium Compounds; Pyrimidines; Quantum Theory; Quinolinium Compounds; Spectrophotometry, Ultraviolet | 2011 |
Synthesis and biological evaluation of a series of thieno-expanded tricyclic purine 2'-deoxy nucleoside analogues.
Topics: Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Guanosine; HeLa Cells; Humans; Imidazoles; Purine Nucleosides; Pyrimidines; Thiophenes; Virus Replication | 2012 |
The conformational flexibility of nucleic acid bases paired in gas phase: a Car-Parrinello molecular dynamics study.
Topics: Base Pairing; Gases; Imidazoles; Molecular Dynamics Simulation; Nucleic Acids; Pyrimidines | 2012 |
Triazolo and imidazo dihydropyrazolopyrimidine potassium channel antagonists.
Topics: Animals; Cell Line; Imidazoles; Isomerism; Kv1.5 Potassium Channel; Mice; Potassium Channel Blockers; Potassium Channels; Protein Binding; Pyrazoles; Pyrimidines; Structure-Activity Relationship; Triazoles | 2013 |
Morphological and pharmacological investigation on some biopotent materials derived from substituted pyrimidine and imidazole enzyme constituents.
Topics: Animals; Antimetabolites; Antioxidants; Bacteria; Bacterial Infections; Cattle; Coordination Complexes; Copper; DNA; DNA Cleavage; Fluorouracil; Fungi; Humans; Imidazoles; Ligands; Microbial Sensitivity Tests; Mycoses; Nickel; Pyrimidines; Zinc | 2014 |
Parameter choice matters: validating probe parameters for use in mixed-solvent simulations.
Topics: 2-Propanol; Acetamides; Acetone; Acetonitriles; Bacterial Proteins; Binding Sites; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Imidazoles; Ligands; Molecular Dynamics Simulation; Molecular Probes; Protein Binding; Pyrimidines; Solvents; Thermodynamics; Thermolysin; Water | 2014 |
Characteristics of metabolic stability and the cell permeability of 2-pyrimidinyl-piperazinyl-alkyl derivatives of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione with antidepressant- and anxiolytic-like activities.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Binding Sites; Imidazoles; Maze Learning; Mice; Microsomes, Liver; Molecular Dynamics Simulation; Permeability; Phosphoric Diester Hydrolases; Piperazine; Protein Binding; Protein Structure, Tertiary; Purines; Pyrimidines; Receptor, Serotonin, 5-HT1A; Structure-Activity Relationship | 2019 |